W Martin Kast - Publications

Affiliations: 
Genetic, Molecular, and Cell Biology University of Southern California, Los Angeles, CA, United States 
Area:
Immunology, Oncology, Cell Biology

185 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Da Silva DM, Martinez EA, Bogaert L, Kast WM. Investigation of the Optimal Prime Boost Spacing Regimen for a Cancer Therapeutic Vaccine Targeting Human Papillomavirus. Cancers. 14. PMID 36077873 DOI: 10.3390/cancers14174339  0.411
2020 Da Silva DM, Enserro DM, Mayadev J, Skeate JG, Matsuo K, Pham HQ, Lankes HA, Moxley KM, Ghamande S, Lin YG, Schilder RJ, Birrer MJ, Kast WM. Immune activation in patients with locally advanced cervical cancer treated with ipilimumab following definitive chemoradiation (GOG-9929). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32816895 DOI: 10.1158/1078-0432.Ccr-20-0776  0.387
2020 Skeate JG, Otsmaa ME, Prins R, Fernandez DJ, Da Silva DM, Kast WM. TNFSF14: LIGHTing the Way for Effective Cancer Immunotherapy. Frontiers in Immunology. 11: 922. PMID 32499782 DOI: 10.3389/Fimmu.2020.00922  0.384
2020 Thornton SM, Samararatne VD, Skeate JG, Buser C, Lühen KP, Taylor JR, Da Silva DM, Kast WM. The Essential Role of anxA2 in Langerhans Cell Birbeck Granules Formation. Cells. 9. PMID 32326440 DOI: 10.3390/Cells9040974  0.34
2020 Garrido G, Schrand B, Levay A, Rabasa Capote A, Ferrantella A, Da Silva DM, D'Eramo F, Marijt KA, Zhang Z, Kwon D, Kortylewski M, Kast WM, Dudeja V, van Hall T, Gilboa E. Vaccination against non-mutated neoantigens induced in recurrent and future tumors. Cancer Immunology Research. PMID 32295785 DOI: 10.1158/2326-6066.Cir-20-0020  0.492
2019 Da Silva DM, Skeate JG, Chavez-Juan E, Lühen KP, Wu JM, Wu CM, Kast WM, Hwang K. Therapeutic efficacy of a human papillomavirus type 16 E7 bacterial exotoxin fusion protein adjuvanted with CpG or GPI-0100 in a preclinical mouse model for HPV-associated disease. Vaccine. PMID 31010714 DOI: 10.1016/J.Vaccine.2019.04.043  0.495
2019 Melas M, Lazaris C, Schmit SL, Maoz A, Pamplona RS, Qu C, Greenson JK, Kuick R, Lejbkowicz F, Rennert HS, Walker CP, Bowen CM, Silva DMD, Kast WM, Idos GE, et al. Abstract 2332: Tumor infiltrating lymphocytes, immunoSeq, and CMS classification in the molecular epidemiology of colorectal cancer study Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2332  0.332
2018 Taylor JR, Fernandez DJ, Thornton SM, Skeate JG, Lühen KP, Da Silva DM, Langen R, Kast WM. Heterotetrameric annexin A2/S100A10 (A2t) is essential for oncogenic human papillomavirus trafficking and capsid disassembly, and protects virions from lysosomal degradation. Scientific Reports. 8: 11642. PMID 30076379 DOI: 10.1038/S41598-018-30051-2  0.368
2018 Woodham AW, Cheloha RW, Ling J, Rashidian M, Kolifrath SC, Mesyngier M, Duarte JN, Bader JM, Skeate JG, Da Silva DM, Kast WM, Ploegh HL. Nanobody-antigen conjugates elicit HPV-specific anti-tumor immune responses. Cancer Immunology Research. PMID 29792298 DOI: 10.1158/2326-6066.Cir-17-0661  0.522
2018 Skeate JG, Da Silva DM, Chavez-Juan E, Anand S, Nuccitelli R, Kast WM. Nano-Pulse Stimulation induces immunogenic cell death in human papillomavirus-transformed tumors and initiates an adaptive immune response. Plos One. 13: e0191311. PMID 29324830 DOI: 10.1371/Journal.Pone.0191311  0.398
2017 Mirandola L, Pedretti E, Figueroa JA, Chiaramonte R, Colombo M, Chapman C, Grizzi F, Patrinicola F, Kast WM, Nguyen DD, Rahman RL, Daver N, Ruvolo P, Post SM, Bresalier RS, et al. Cancer testis antigen Sperm Protein 17 as a new target for triple negative breast cancer immunotherapy. Oncotarget. 8: 74378-74390. PMID 29088794 DOI: 10.18632/Oncotarget.20102  0.375
2017 García-Hernández ML, Uribe-Uribe NO, Espinosa-González R, Kast WM, Khader SA, Rangel-Moreno J. A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression. Frontiers in Immunology. 8: 563. PMID 28567040 DOI: 10.3389/Fimmu.2017.00563  0.357
2016 Pulido MA, DerHartunian MK, Qin Z, Chung EM, Kang DS, Woodham AW, Tsou JA, Klooster R, Akbari O, Wang L, Kast WM, Liu SV, Verschuuren JJ, Aswad DW, Laird-Offringa IA. Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4. Journal of Neuroimmunology. 299: 70-78. PMID 27725125 DOI: 10.1016/J.Jneuroim.2016.09.002  0.365
2016 Woodham AW, Yan L, Skeate JG, van der Veen D, Brand HH, Wong MK, Da Silva DM, Kast WM. T cell ignorance is bliss: T cells are not tolerized by Langerhans cells presenting human papillomavirus antigens in the absence of costimulation. Papillomavirus Research. 2: 21-30. PMID 27182559 DOI: 10.1016/J.Pvr.2016.01.002  0.436
2016 Nicol AF, Brunette LL, Nuovo GJ, Grinsztejn B, Friedman RK, Veloso VG, Cunha CB, Coutinho JR, Vianna-Andrade C, Oliveira NS, Woodham AW, da Silva DM, Kast WM. Secretory leukocyte protease inhibitor expression and high-risk HPV infection in anal lesions of HIV positive patients. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27149102 DOI: 10.1097/Qai.0000000000001049  0.302
2016 Skeate JG, Woodham AW, Einstein MH, Da Silva DM, Kast WM. Current therapeutic vaccination and immunotherapy strategies for HPV-related diseases. Human Vaccines & Immunotherapeutics. 0. PMID 26835746 DOI: 10.1080/21645515.2015.1136039  0.471
2015 Da Silva DM, Woodham AW, Rijkee LK, Skeate JG, Taylor JR, Koopman ME, Brand HE, Wong MK, McKee GM, Salazar AM, Kast WM. Human papillomavirus-exposed Langerhans cells are activated by stabilized Poly-I:C. Papillomavirus Research. 1: 12-21. PMID 26665182 DOI: 10.1016/J.Pvr.2015.05.001  0.426
2015 Da Silva DM, Woodham AW, Naylor PH, Egan JE, Berinstein NL, Kast WM. Immunostimulatory Activity of the Cytokine-Based Biologic, IRX-2, on Human Papillomavirus-Exposed Langerhans Cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. PMID 26653678 DOI: 10.1089/Jir.2015.0115  0.455
2015 Skeate JG, Porras TB, Woodham AW, Jang JK, Taylor JR, Brand HE, Kelly TJ, Jung JU, Da Silva DM, Yuan W, Kast WM. Herpes Simplex Virus downregulation of secretory leukocyte protease inhibitor enhances Human Papillomavirus type 16 infection. The Journal of General Virology. PMID 26555393 DOI: 10.1099/Jgv.0.000341  0.382
2015 Bogaert L, Woodham AW, Da Silva DM, Martens A, Meyer E, Kast WM. A novel murine model for evaluating bovine papillomavirus prophylactics/therapeutics for equine sarcoid-like tumours. The Journal of General Virology. 96: 2764-8. PMID 26044793 DOI: 10.1099/Vir.0.000212  0.332
2015 Woodham AW, Taylor JR, Jimenez AI, Skeate JG, Schmidt T, Brand HE, Da Silva DM, Kast WM. Small molecule inhibitors of the annexin A2 heterotetramer prevent human papillomavirus type 16 infection. The Journal of Antimicrobial Chemotherapy. 70: 1686-90. PMID 25712315 DOI: 10.1093/Jac/Dkv045  0.363
2015 Yan L, Silva DM, Verma B, Gray A, Brand HE, Skeate JG, Porras TB, Kanodia S, Kast WM. Forced LIGHT expression in prostate tumors overcomes Treg mediated immunosuppression and synergizes with a prostate tumor therapeutic vaccine by recruiting effector T lymphocytes. The Prostate. 75: 280-91. PMID 25399517 DOI: 10.1002/Pros.22914  0.57
2015 Yan L, Woodham AW, Da Silva DM, Kast WM. Functional analysis of HPV-like particle-activated Langerhans cells in vitro. Methods in Molecular Biology (Clifton, N.J.). 1249: 333-50. PMID 25348318 DOI: 10.1007/978-1-4939-2013-6_25  0.46
2015 Woodham AW, Raff AB, Da Silva DM, Kast WM. Molecular analysis of human papillomavirus virus-like particle activated Langerhans cells in vitro. Methods in Molecular Biology (Clifton, N.J.). 1249: 135-49. PMID 25348303 DOI: 10.1007/978-1-4939-2013-6_10  0.415
2015 Larsen RA, Rodgers KE, Kast WM, Silva DD, Altomstone R, Meeks C, diZerga GS, Leedom JM. Topical Mucosal Vaccination with Angiotensin (1-7) and Feline Immunodeficiency Virus Induces Secretory IgA Responses Journal of Medical Microbiology and Diagnosis. 4. DOI: 10.4172/2161-0703.1000179  0.402
2014 Woodham AW, Raff AB, Raff LM, Da Silva DM, Yan L, Skeate JG, Wong MK, Lin YG, Kast WM. Inhibition of Langerhans cell maturation by human papillomavirus type 16: a novel role for the annexin A2 heterotetramer in immune suppression. Journal of Immunology (Baltimore, Md. : 1950). 192: 4748-57. PMID 24719459 DOI: 10.4049/Jimmunol.1303190  0.414
2014 Da Silva DM, Movius CA, Raff AB, Brand HE, Skeate JG, Wong MK, Kast WM. Suppression of Langerhans cell activation is conserved amongst human papillomavirus α and β genotypes, but not a µ genotype. Virology. 452: 279-86. PMID 24606705 DOI: 10.1016/J.Virol.2014.01.031  0.384
2014 Pulido MA, Lombardi V, Lee D, Wang Y, Chung E, Wang L, Kast WM, Akbari O, Laird-Offringa IA. Abstract 3623: Fluctuating antibody response and CD4-positive T-cells in a small-cell lung cancer mouse model Cancer Research. 74: 3623-3623. DOI: 10.1158/1538-7445.Am2014-3623  0.401
2013 Hoffmann M, Quabius ES, Tribius S, Hebebrand L, Görögh T, Halec G, Kahn T, Hedderich J, Röcken C, Haag J, Waterboer T, Schmitt M, Giuliano AR, Kast WM. Human papillomavirus infection in head and neck cancer: the role of the secretory leukocyte protease inhibitor. Oncology Reports. 29: 1962-8. PMID 23467841 DOI: 10.3892/Or.2013.2327  0.355
2012 Schwartz RL, Jayaratna IS, Mitra AP, Da Silva D, Kast WM, Chen M, Ma Y, Quinn DI, Dorff TB, Schuckman A. HPV status in relation to clinicopathologic variables in patients with penile cancer at Los Angeles County-USC Medical Center. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 329. PMID 27967939 DOI: 10.1200/Jco.2012.30.5_Suppl.329  0.376
2012 Pandey A, Kurup A, Shrivastava A, Radhi S, Nguyen DD, Arentz C, D'Chuna N, Hardwick F, D'Souza MJ, Jenkins M, Grizzi F, Kast WM, Cobos E, Rahman R, Chiriva-Internati M, et al. Cancer testes antigens in breast cancer: biological role, regulation, and therapeutic applicability. International Reviews of Immunology. 31: 302-20. PMID 23083343 DOI: 10.3109/08830185.2012.723511  0.328
2012 Woodham AW, Da Silva DM, Skeate JG, Raff AB, Ambroso MR, Brand HE, Isas JM, Langen R, Kast WM. The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection. Plos One. 7: e43519. PMID 22927980 DOI: 10.1371/Journal.Pone.0043519  0.367
2012 Jenkins M, Chiriva-Internati M, Mirandola L, Tonroy C, Tedjarati SS, Davis N, D'Cunha N, Tijani L, Hardwick F, Nguyen D, Kast WM, Cobos E. Perspective for prophylaxis and treatment of cervical cancer: an immunological approach. International Reviews of Immunology. 31: 3-21. PMID 22251005 DOI: 10.3109/08830185.2011.637254  0.416
2012 Chiriva-Internati M, Kast WM, Bot A. In this issue: targeting Human Papilloma Virus-associated disease, from cervical to head and neck carcinoma…and more. International Reviews of Immunology. 31: 1-2. PMID 22251004 DOI: 10.3109/08830185.2011.646203  0.384
2012 Mirandola L, Chiriva-Internati M, Montagna D, Locatelli F, Zecca M, Ranzani M, Basile A, Locati M, Cobos E, Kast WM, Asselta R, Paraboschi EM, Comi P, Chiaramonte R. Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia. The Journal of Pathology. 226: 713-22. PMID 21984373 DOI: 10.1002/Path.3015  0.324
2012 Chiriva-Internati M, Yu Y, Mirandola L, D'Cunha N, Hardwicke F, Cannon MJ, Cobos E, Kast WM. Identification of AKAP-4 as a new cancer/testis antigen for detection and immunotherapy of prostate cancer. The Prostate. 72: 12-23. PMID 21520158 DOI: 10.1002/Pros.21400  0.357
2011 Chiriva-Internati M, Mirandola L, Yu Y, Jenkins MR, Gornati R, Bernardini G, Gioia M, Chiaramonte R, Cannon MJ, Kast WM, Cobos E. Cancer testis antigen, ropporin, is a potential target for multiple myeloma immunotherapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 34: 490-9. PMID 21654522 DOI: 10.1097/Cji.0B013E31821Ca76F  0.394
2011 Mirandola L, Comi P, Cobos E, Kast WM, Chiriva-Internati M, Chiaramonte R. Notch-ing from T-cell to B-cell lymphoid malignancies. Cancer Letters. 308: 1-13. PMID 21652011 DOI: 10.1016/J.Canlet.2011.05.009  0.332
2011 Mirandola L, J Cannon M, Cobos E, Bernardini G, Jenkins MR, Kast WM, Chiriva-Internati M. Cancer testis antigens: novel biomarkers and targetable proteins for ovarian cancer. International Reviews of Immunology. 30: 127-37. PMID 21557639 DOI: 10.3109/08830185.2011.572504  0.397
2011 Chiriva-Internati M, Mirandola L, Kast WM, Jenkins MR, Cobos E, Cannon MJ. Understanding the cross-talk between ovarian tumors and immune cells: mechanisms for effective immunotherapies. International Reviews of Immunology. 30: 71-86. PMID 21557635 DOI: 10.3109/08830185.2011.561507  0.383
2011 Kanodia S, Kast WM. Perspectives for prophylactic and therapeutic vaccination for HPV-induced lesions Human Papillomavirus Vaccines. 69-79. DOI: 10.2217/EBO.11.31  0.386
2010 Gray A, Yan L, Kast WM. Prevention is better than cure: the case for clinical trials of therapeutic cancer vaccines in the prophylactic setting. Molecular Interventions. 10: 197-203. PMID 20729485 DOI: 10.1124/mi.10.4.2  0.461
2010 Chiriva-Internati M, Yu Y, Mirandola L, Jenkins MR, Chapman C, Cannon M, Cobos E, Kast WM. Cancer testis antigen vaccination affords long-term protection in a murine model of ovarian cancer. Plos One. 5: e10471. PMID 20485677 DOI: 10.1371/Journal.Pone.0010471  0.474
2010 Kanodia S, Da Silva DM, Karamanukyan T, Bogaert L, Fu YX, Kast WM. Expression of LIGHT/TNFSF14 combined with vaccination against human papillomavirus Type 16 E7 induces significant tumor regression. Cancer Research. 70: 3955-64. PMID 20460520 DOI: 10.1158/0008-5472.Can-09-3773  0.47
2009 Gray A, de la Luz Garcia-Hernandez M, van West M, Kanodia S, Hubby B, Kast WM. Prostate cancer immunotherapy yields superior long-term survival in TRAMP mice when administered at an early stage of carcinogenesis prior to the establishment of tumor-associated immunosuppression at later stages. Vaccine. 27: G52-9. PMID 20006141 DOI: 10.1016/J.Vaccine.2009.09.106  0.557
2009 Fahey LM, Raff AB, Da Silva DM, Kast WM. A major role for the minor capsid protein of human papillomavirus type 16 in immune escape. Journal of Immunology (Baltimore, Md. : 1950). 183: 6151-6. PMID 19864613 DOI: 10.4049/Jimmunol.0902145  0.407
2009 Smith KA, Meisenburg BL, Tam VL, Pagarigan RR, Wong R, Joea DK, Lantzy L, Carrillo MA, Gross TM, Malyankar UM, Chiang CS, Da Silva DM, Kündig TM, Kast WM, Qiu Z, et al. Lymph node-targeted immunotherapy mediates potent immunity resulting in regression of isolated or metastatic human papillomavirus-transformed tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 6167-76. PMID 19789304 DOI: 10.1158/1078-0432.Ccr-09-0645  0.438
2009 Chiriva-Internati M, Gagliano N, Donetti E, Costa F, Grizzi F, Franceschini B, Albani E, Levi-Setti PE, Gioia M, Jenkins M, Cobos E, Kast WM. Sperm protein 17 is expressed in the sperm fibrous sheath. Journal of Translational Medicine. 7: 61. PMID 19604394 DOI: 10.1186/1479-5876-7-61  0.304
2009 Hitzeroth II, Passmore JA, Shephard E, Stewart D, Müller M, Williamson AL, Rybicki EP, Kast WM. Immunogenicity of an HPV-16 L2 DNA vaccine. Vaccine. 27: 6432-4. PMID 19559114 DOI: 10.1016/J.Vaccine.2009.06.015  0.419
2009 Leffers N, Gooden MJ, Mokhova AA, Kast WM, Boezen HM, Ten Hoor KA, Hollema H, Daemen T, van der Zee AG, Nijman HW. Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer. Gynecologic Oncology. 113: 256-63. PMID 19243813 DOI: 10.1016/J.Ygyno.2008.12.030  0.314
2009 Fahey LM, Raff AB, Da Silva DM, Kast WM. Reversal of human papillomavirus-specific T cell immune suppression through TLR agonist treatment of Langerhans cells exposed to human papillomavirus type 16. Journal of Immunology (Baltimore, Md. : 1950). 182: 2919-28. PMID 19234187 DOI: 10.4049/Jimmunol.0803645  0.413
2009 Koh YT, Gray A, Higgins SA, Hubby B, Kast WM. Androgen ablation augments prostate cancer vaccine immunogenicity only when applied after immunization. The Prostate. 69: 571-84. PMID 19143030 DOI: 10.1002/Pros.20906  0.754
2009 Raff AB, Gray A, Kast WM. Prostate stem cell antigen: a prospective therapeutic and diagnostic target. Cancer Letters. 277: 126-32. PMID 18838214 DOI: 10.1016/J.Canlet.2008.08.034  0.517
2009 Moore TV, Lyons GE, Brasic N, Roszkowski JJ, Voelkl S, Mackensen A, Kast WM, Le Poole IC, Nishimura MI. Relationship between CD8-dependent antigen recognition, T cell functional avidity, and tumor cell recognition. Cancer Immunology, Immunotherapy : Cii. 58: 719-28. PMID 18836717 DOI: 10.1007/S00262-008-0594-2  0.387
2008 Yu Y, Pilgrim P, Zhou W, Gagliano N, Frezza EE, Jenkins M, Weidanz JA, Lustgarten J, Cannon M, Bumm K, Cobos E, Kast WM, Chiriva-Internati M. rAAV/Her-2/neu loading of dendritic cells for a potent cellular-mediated MHC class I restricted immune response against ovarian cancer. Viral Immunology. 21: 435-42. PMID 19115932 DOI: 10.1089/Vim.2008.0029  0.452
2008 Kanodia S, Kast WM. Peptide-based vaccines for cancer: realizing their potential. Expert Review of Vaccines. 7: 1533-45. PMID 19053209 DOI: 10.1586/14760584.7.10.1533  0.394
2008 Yu Y, Pilgrim P, Yan J, Zhou W, Jenkins M, Gagliano N, Bumm K, Cannon M, Milzani A, Dalle-Donne I, Kast WM, Cobos E, Chiriva-Internati M. Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells. Journal of Translational Medicine. 6: 56. PMID 18834548 DOI: 10.1186/1479-5876-6-56  0.385
2008 Chiriva-Internati M, Weidanz JA, Yu Y, Frezza EE, Jenkins MR, Kennedy RC, Cobos E, Kast WM. Sperm protein 17 is a suitable target for adoptive T-cell-based immunotherapy in human ovarian cancer. Journal of Immunotherapy (Hagerstown, Md. : 1997). 31: 693-703. PMID 18779750 DOI: 10.1097/Cji.0B013E31818283D5  0.403
2008 Chiriva-Internati M, Cobos E, Da Silva DM, Kast WM. Sperm fibrous sheath proteins: a potential new class of target antigens for use in human therapeutic cancer vaccines. Cancer Immunity. 8: 8. PMID 18433090  0.311
2008 Chiriva-Internati M, Ferrari R, Prabhakar M, Yu Y, Baggoni L, Moreno J, Gagliano N, Portinaro N, Jenkins MR, Frezza EE, Hardwicke F, D'Cunha N, Kast W, Cobos E. The pituitary tumor transforming gene 1 (PTTG-1): an immunological target for multiple myeloma. Journal of Translational Medicine. 6: 15. PMID 18384692 DOI: 10.1186/1479-5876-6-15  0.38
2008 Gray A, Raff AB, Chiriva-Internati M, Chen SY, Kast WM. A paradigm shift in therapeutic vaccination of cancer patients: the need to apply therapeutic vaccination strategies in the preventive setting. Immunological Reviews. 222: 316-27. PMID 18364011 DOI: 10.1111/J.1600-065X.2008.00605.X  0.598
2008 Garcia-Hernandez Mde L, Gray A, Hubby B, Klinger OJ, Kast WM. Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity. Cancer Research. 68: 861-9. PMID 18245488 DOI: 10.1158/0008-5472.Can-07-0445  0.581
2008 Chiriva-Internati M, Ferrari R, Yu Y, Hamrick C, Gagliano N, Grizzi F, Frezza E, Jenkins MR, Hardwick F, D'Cunha N, Kast WM, Cobos E. AKAP-4: a novel cancer testis antigen for multiple myeloma. British Journal of Haematology. 140: 465-8. PMID 18217892 DOI: 10.1111/J.1365-2141.2007.06940.X  0.372
2008 Le Poole IC, ElMasri WM, Denman CJ, Kroll TM, Bommiasamy H, Lyons Eiben G, Kast WM. Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells. Cancer Immunology, Immunotherapy : Cii. 57: 789-97. PMID 18004565 DOI: 10.1007/S00262-007-0415-Z  0.443
2008 Kanodia S, Da Silva DM, Kast WM. Recent advances in strategies for immunotherapy of human papillomavirus-induced lesions. International Journal of Cancer. Journal International Du Cancer. 122: 247-59. PMID 17973257 DOI: 10.1002/Ijc.23252  0.461
2008 Janetzki S, Panageas KS, Ben-Porat L, Boyer J, Britten CM, Clay TM, Kalos M, Maecker HT, Romero P, Yuan J, Kast WM, Hoos A. Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI). Cancer Immunology, Immunotherapy : Cii. 57: 303-15. PMID 17721781 DOI: 10.1007/S00262-007-0380-6  0.345
2007 Brinkman JA, Hughes SH, Stone P, Caffrey AS, Muderspach LI, Roman LD, Weber JS, Kast WM. Therapeutic vaccination for HPV induced cervical cancers. Disease Markers. 23: 337-52. PMID 17627067 DOI: 10.1155/2007/245146  0.469
2007 Chiriva-Internati M, Cobos E, Kast WM. Advances in immunotherapy of multiple myeloma: from the discovery of tumor-associated antigens to clinical trials. International Reviews of Immunology. 26: 197-222. PMID 17558744 DOI: 10.1080/08830180701365966  0.4
2007 Daftarian PM, Mansour M, Pohajdak B, Fuentes-Ortega A, Korets-Smith E, Macdonald L, Weir G, Brown RG, Kast WM. Rejection of large HPV-16 expressing tumors in aged mice by a single immunization of VacciMax encapsulated CTL/T helper peptides. Journal of Translational Medicine. 5: 26. PMID 17555571 DOI: 10.1186/1479-5876-5-26  0.491
2007 Da Silva DM, Fausch SC, Verbeek JS, Kast WM. Uptake of human papillomavirus virus-like particles by dendritic cells is mediated by Fcgamma receptors and contributes to acquisition of T cell immunity. Journal of Immunology (Baltimore, Md. : 1950). 178: 7587-97. PMID 17548594 DOI: 10.4049/Jimmunol.178.12.7587  0.454
2007 Mansour M, Pohajdak B, Kast WM, Fuentes-Ortega A, Korets-Smith E, Weir GM, Brown RG, Daftarian P. Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax. Journal of Translational Medicine. 5: 20. PMID 17451606 DOI: 10.1186/1479-5876-5-20  0.48
2007 Chiriva-Internati M, Grizzi F, Weidanz JA, Ferrari R, Yuefei Y, Velez B, Shearer MH, Lowe DB, Frezza EE, Cobos E, Kast WM, Kennedy RC. A NOD/SCID tumor model for human ovarian cancer that allows tracking of tumor progression through the biomarker Sp17. Journal of Immunological Methods. 321: 86-93. PMID 17336323 DOI: 10.1016/J.Jim.2007.01.010  0.377
2007 Kanodia S, Fahey LM, Kast WM. Mechanisms used by human papillomaviruses to escape the host immune response. Current Cancer Drug Targets. 7: 79-89. PMID 17305480 DOI: 10.2174/156800907780006869  0.396
2007 Garcia-Hernandez Mde L, Gray A, Hubby B, Kast WM. In vivo effects of vaccination with six-transmembrane epithelial antigen of the prostate: a candidate antigen for treating prostate cancer. Cancer Research. 67: 1344-51. PMID 17283172 DOI: 10.1158/0008-5472.Can-06-2996  0.609
2007 Brinkman JA, Xu X, Kast WM. The efficacy of a DNA vaccine containing inserted and replicated regions of the E7 gene for treatment of HPV-16 induced tumors. Vaccine. 25: 3437-44. PMID 17241713 DOI: 10.1016/J.Vaccine.2006.12.045  0.472
2006 Koh YT, Higgins SA, Weber JS, Kast WM. Immunological consequences of using three different clinical/laboratory techniques of emulsifying peptide-based vaccines in incomplete Freund's adjuvant. Journal of Translational Medicine. 4: 42. PMID 17059610 DOI: 10.1186/1479-5876-4-42  0.714
2006 Chiriva-Internati M, Grizzi F, Pinkston J, Morrow KJ, D'Cunha N, Frezza EE, Muzzio PC, Kast WM, Cobos E. Gamma-radiation upregulates MHC class I/II and ICAM-I molecules in multiple myeloma cell lines and primary tumors. In Vitro Cellular & Developmental Biology. Animal. 42: 89-95. PMID 16759154 DOI: 10.1290/0508054.1  0.358
2006 Daftarian P, Mansour M, Benoit AC, Pohajdak B, Hoskin DW, Brown RG, Kast WM. Eradication of established HPV 16-expressing tumors by a single administration of a vaccine composed of a liposome-encapsulated CTL-T helper fusion peptide in a water-in-oil emulsion. Vaccine. 24: 5235-44. PMID 16675074 DOI: 10.1016/J.Vaccine.2006.03.079  0.513
2006 Lyons GE, Roszkowski JJ, Man S, Yee C, Kast WM, Nishimura MI. T-cell receptor tetramer binding or the lack there of does not necessitate antigen reactivity in T-cell receptor transduced T cells. Cancer Immunology, Immunotherapy : Cii. 55: 1142-50. PMID 16374636 DOI: 10.1007/S00262-005-0103-9  0.417
2005 Da Silva DM, Kast WM. Vaccination Against Cervical Cancer: Hopes and Realities. American Journal of Cancer (Auckland, N.Z.). 4: 207-219. PMID 34566405 DOI: 10.2165/00024669-200504040-00001  0.334
2005 Warrino DE, Olson WC, Scarrow MI, D'Ambrosio-Brennan LJ, Guido RS, Da Silva DM, Kast WM, Storkus WJ. Human papillomavirus L1L2-E7 virus-like particles partially mature human dendritic cells and elicit E7-specific T-helper responses from patients with cervical intraepithelial neoplasia or cervical cancer in vitro Human Immunology. 66: 762-772. PMID 16112023 DOI: 10.1016/J.Humimm.2005.04.006  0.426
2005 Fausch SC, Fahey LM, Da Silva DM, Kast WM. Human papillomavirus can escape immune recognition through Langerhans cell phosphoinositide 3-kinase activation. Journal of Immunology (Baltimore, Md. : 1950). 174: 7172-8. PMID 15905561 DOI: 10.4049/Jimmunol.174.11.7172  0.399
2005 Brinkman JA, Caffrey AS, Muderspach LI, Roman LD, Kast WM. The impact of anti HPV vaccination on cervical cancer incidence and HPV induced cervical lesions: consequences for clinical management. European Journal of Gynaecological Oncology. 26: 129-42. PMID 15857016  0.356
2005 Roszkowski JJ, Lyons GE, Kast WM, Yee C, Van Besien K, Nishimura MI. Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor. Cancer Research. 65: 1570-6. PMID 15735047 DOI: 10.1158/0008-5472.Can-04-2076  0.411
2005 Fausch SC, Da Silva DM, Kast WM. Heterologous papillomavirus virus-like particles and human papillomavirus virus-like particle immune complexes activate human Langerhans cells. Vaccine. 23: 1720-9. PMID 15705478 DOI: 10.1016/J.Vaccine.2004.09.035  0.462
2005 Da Silva DM, Kast WM. Vaccination against cervical cancer: Hopes and realities American Journal of Cancer. 4: 207-219. DOI: 10.2165/00024669-200504040-00001  0.44
2004 Markiewicz MA, Kast WM. Progress in the development of immunotherapy of cancer using ex vivo-generated dendritic cells expressing multiple tumor antigen epitopes. Cancer Investigation. 22: 417-34. PMID 15493363 DOI: 10.1081/Cnv-200029072  0.474
2004 Kast WM, Levitsky H, Marincola FM. Synopsis of the 6th Walker's Cay Colloquium on Cancer Vaccines and Immunotherapy. Journal of Translational Medicine. 2: 20. PMID 15212694 DOI: 10.1186/1479-5876-2-20  0.455
2004 Warrino DE, Olson WC, Knapp WT, Scarrow MI, D'Ambrosio-Brennan LJ, Guido RS, Edwards RP, Kast WM, Storkus WJ. Disease-stage variance in functional CD4+ T-cell responses against novel pan-human leukocyte antigen-D region presented human papillomavirus-16 E7 epitopes Clinical Cancer Research. 10: 3301-3308. PMID 15161683 DOI: 10.1158/1078-0432.Ccr-03-0498  0.424
2004 Schreiber K, Cannon RE, Karrison T, Beck-Engeser G, Huo D, Tennant RW, Jensen H, Kast WM, Krausz T, Meredith SC, Chen L, Schreiber H. Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors. Oncogene. 23: 3972-9. PMID 15077191 DOI: 10.1038/Sj.Onc.1207507  0.345
2004 Brinkman JA, Fausch SC, Weber JS, Kast WM. Peptide-based vaccines for cancer immunotherapy. Expert Opinion On Biological Therapy. 4: 181-98. PMID 14998777 DOI: 10.1517/14712598.4.2.181  0.443
2004 Cassetti MC, McElhiney SP, Shahabi V, Pullen JK, Le Poole IC, Eiben GL, Smith LR, Kast WM. Antitumor efficacy of Venezuelan equine encephalitis virus replicon particles encoding mutated HPV16 E6 and E7 genes. Vaccine. 22: 520-7. PMID 14670335 DOI: 10.1016/J.Vaccine.2003.07.003  0.43
2004 Wilcox RA, Tamada K, Flies DB, Zhu G, Chapoval AI, Blazar BR, Kast WM, Chen L. Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo. Blood. 103: 177-84. PMID 12969968 DOI: 10.1182/Blood-2003-06-2184  0.367
2004 Brinkman JA, Caffrey AS, Muderspach LI, Roman LD, Kast WM. The impact of anti-HPV vaccination on cervical cancer incidence and HPV-induced cervical lesions: Consequences for clinical management Cme Journal of Gynecologic Oncology. 9: 217-230.  0.356
2003 Velders MP, Markiewicz MA, Eiben GL, Kast WM. CD4+ T cell matters in tumor immunity. International Reviews of Immunology. 22: 113-40. PMID 12962272 DOI: 10.1080/08830180305220  0.367
2003 Mitchell MS, Kast WM. Synopsis of the 5th annual Cancer Vaccines and Immunotherapy Colloquium at Walker's Cay. Cancer Immunology, Immunotherapy : Cii. 52: 655-60. PMID 12942201 DOI: 10.1007/S00262-003-0438-Z  0.397
2003 Le Poole IC, Bommiasamy H, Bocchetta M, Kast WM. Advances in prophylactic cancer vaccine research. Expert Review of Anticancer Therapy. 3: 537-45. PMID 12934665 DOI: 10.1586/14737140.3.4.537  0.434
2003 Eiben GL, da Silva DM, Fausch SC, Le Poole IC, Nishimura MI, Kast WM. Cervical cancer vaccines: recent advances in HPV research. Viral Immunology. 16: 111-21. PMID 12828864 DOI: 10.1089/088282403322017866  0.411
2003 Da Silva DM, Schiller JT, Kast WM. Heterologous boosting increases immunogenicity of chimeric papillomavirus virus-like particle vaccines. Vaccine. 21: 3219-27. PMID 12804851 DOI: 10.1016/S0264-410X(03)00237-8  0.509
2003 Le Poole IC, Bommiasamy H, Kast WM. Recent progress in tumour vaccine development. Expert Opinion On Investigational Drugs. 12: 971-81. PMID 12783601 DOI: 10.1517/13543784.12.6.971  0.417
2003 Kotecha MT, Afghan RK, Vasilikopoulou E, Wilson E, Marsh P, Kast WM, Davies DH, Caparros-Wanderley W. Enhanced tumour growth after DNA vaccination against human papilloma virus E7 oncoprotein: evidence for tumour-induced immune deviation. Vaccine. 21: 2506-15. PMID 12744885 DOI: 10.1016/S0264-410X(03)00043-4  0.473
2003 Weijzen S, Zlobin A, Braid M, Miele L, Kast WM. HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation. Journal of Cellular Physiology. 194: 356-62. PMID 12548555 DOI: 10.1002/Jcp.10217  0.323
2003 Fausch SC, Da Silva DM, Eiben GL, Le Poole IC, Kast WM. HPV protein/peptide vaccines: from animal models to clinical trials. Frontiers in Bioscience : a Journal and Virtual Library. 8: s81-91. PMID 12456298 DOI: 10.2741/1009  0.44
2003 Markiewicz MA, Kast WM. Advances in immunotherapyfor prostate cancer Advances in Cancer Research. 87: 159-194. DOI: 10.1016/S0065-230X(03)87297-4  0.342
2003 Kast WM. Session V: Strategies for immunization - Venezuelan equine encephalitis virus for treatment of cervical cancer Cancer Immunology, Immunotherapy. 52.  0.42
2002 Wakabayashi MT, Da Silva DM, Potkul RK, Kast WM. Comparison of human papillomavirus type 16 L1 chimeric virus-like particles versus L1/L2 chimeric virus-like particles in tumor prevention. Intervirology. 45: 300-7. PMID 12566713 DOI: 10.1159/000067921  0.404
2002 Le Poole IC, Gerberi MA, Kast WM. Emerging strategies in tumor vaccines. Current Opinion in Oncology. 14: 641-8. PMID 12409655 DOI: 10.1097/00001622-200211000-00009  0.456
2002 Eiben GL, Velders MP, Schreiber H, Cassetti MC, Pullen JK, Smith LR, Kast WM. Establishment of an HLA-A*0201 human papillomavirus type 16 tumor model to determine the efficacy of vaccination strategies in HLA-A*0201 transgenic mice. Cancer Research. 62: 5792-9. PMID 12384540  0.384
2002 Eiben GL, Velders MP, Kast WM. The cell-mediated immune response to human papillomavirus-induced cervical cancer: implications for immunotherapy. Advances in Cancer Research. 86: 113-48. PMID 12374277  0.319
2002 Weijzen S, Velders MP, Elmishad AG, Bacon PE, Panella JR, Nickoloff BJ, Miele L, Kast WM. The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 4273-8. PMID 12370358 DOI: 10.4049/Jimmunol.169.8.4273  0.361
2002 Fausch SC, Da Silva DM, Rudolf MP, Kast WM. Human papillomavirus virus-like particles do not activate Langerhans cells: a possible immune escape mechanism used by human papillomaviruses. Journal of Immunology (Baltimore, Md. : 1950). 169: 3242-9. PMID 12218143 DOI: 10.4049/Jimmunol.169.6.3242  0.439
2002 Keilholz U, Weber J, Finke JH, Gabrilovich DI, Kast WM, Disis ML, Kirkwood JM, Scheibenbogen C, Schlom J, Maino VC, Lyerly HK, Lee PP, Storkus W, Marincola F, Worobec A, et al. Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 25: 97-138. PMID 12074049 DOI: 10.1097/00002371-200203000-00001  0.422
2002 Salit RB, Kast WM, Velders MP. Ins and outs of clinical trials with peptide-based vaccines. Frontiers in Bioscience : a Journal and Virtual Library. 7: e204-13. PMID 11991853 DOI: 10.2741/Salit  0.453
2002 Schreiber H, Wu TH, Nachman J, Kast WM. Immunodominance and tumor escape. Seminars in Cancer Biology. 12: 25-31. PMID 11926408 DOI: 10.1006/Scbi.2001.0401  0.345
2002 Le Poole IC, Riker AI, Quevedo ME, Stennett LS, Wang E, Marincola FM, Kast WM, Robinson JK, Nickoloff BJ. Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cells. The American Journal of Pathology. 160: 521-8. PMID 11839572 DOI: 10.1016/S0002-9440(10)64871-7  0.407
2001 Visser M, Velders MP, Rudolf MP, Kast WM. Molecular characterization of melanoma-derived antigens. Methods in Molecular Medicine. 61: 31-70. PMID 22323251 DOI: 10.1385/1-59259-145-0:31  0.397
2001 Da Silva DM, Pastrana DV, Schiller JT, Kast WM. Effect of preexisting neutralizing antibodies on the anti-tumor immune response induced by chimeric human papillomavirus virus-like particle vaccines. Virology. 290: 350-60. PMID 11883199 DOI: 10.1006/Viro.2001.1179  0.468
2001 Mercader M, Bodner BK, Moser MT, Kwon PS, Park ESY, Manecke RG, Ellis TM, Wojcik EM, Yang D, Flanigan RC, Waters WB, Kast WM, Kwon ED. T cell infiltration of the prostate induced by androgen withdrawal in patients with prostate cancer Proceedings of the National Academy of Sciences of the United States of America. 98: 14565-14570. PMID 11734652 DOI: 10.1073/Pnas.251140998  0.39
2001 Velders MP, McElhiney S, Cassetti MC, Eiben GL, Higgins T, Kovacs GR, Elmishad AG, Kast WM, Smith LR. Eradication of established tumors by vaccination with Venezuelan equine encephalitis virus replicon particles delivering human papillomavirus 16 E7 RNA. Cancer Research. 61: 7861-7. PMID 11691804  0.407
2001 Velders MP, Macedo MF, Provenzano M, Elmishad AG, Holzhütter HG, Carbone M, Kast WM. Human T cell responses to endogenously presented HLA-A*0201 restricted peptides of Simian virus 40 large T antigen. Journal of Cellular Biochemistry. 82: 155-62. PMID 11400172 DOI: 10.1002/Jcb.1148  0.417
2001 Weijzen S, Meredith SC, Velders MP, Elmishad AG, Schreiber H, Kast WM. Pharmacokinetic differences between a T cell-tolerizing and a T cell-activating peptide Journal of Immunology. 166: 7151-7157. PMID 11390461 DOI: 10.4049/Jimmunol.166.12.7151  0.415
2001 Rudolf MP, Fausch SC, Da Silva DM, Kast WM. Human dendritic cells are activated by chimeric human papillomavirus type-16 virus-like particles and induce epitope-specific human T cell responses in vitro Journal of Immunology. 166: 5917-5924. PMID 11342606 DOI: 10.4049/Jimmunol.166.10.5917  0.476
2001 Gabrilovich DI, Velders MP, Sotomayor EM, Kast WM. Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells Journal of Immunology. 166: 5398-5406. PMID 11313376 DOI: 10.4049/Jimmunol.166.9.5398  0.432
2001 Velders MP, Weijzen S, Eiben GL, Elmishad AG, Kloetzel P, Higgins T, Ciccarelli RB, Evans M, Man S, Smith L, Kast WM. Defined Flanking Spacers and Enhanced Proteolysis Is Essential for Eradication of Established Tumors by an Epitope String DNA Vaccine Journal of Immunology. 166: 5366-5373. PMID 11313372 DOI: 10.4049/Jimmunol.166.9.5366  0.438
2001 Da Silva DM, Velders MP, Nieland JD, Schiller JT, Nickoloff BJ, Kast WM. Physical interaction of human papillomavirus virus-like particles with immune cells International Immunology. 13: 633-641. PMID 11312251 DOI: 10.1093/Intimm/13.5.633  0.435
2001 Small LA, Da Silva DM, de Visser KE, Velders MP, Fisher SG, Potkul RK, Kast WM. A murine model for the effects of pelvic radiation and cisplatin chemotherapy on human papillomavirus vaccine efficacy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 876s-881s. PMID 11300486  0.381
2001 Schreiber K, Wu TH, Kast WM, Schreiber H. Tracking the common ancestry of antigenically distinct cancer variants. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 871s-875s. PMID 11300485  0.323
2001 Rudolf MP, Man S, Melief CJM, Sette A, Kast WM. Human T-cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7 Clinical Cancer Research. 7. PMID 11300474  0.331
2001 Da Silva DM, Eiben GL, Fausch SC, Wakabayashi MT, Rudolf MP, Velders MP, Kast WM. Cervical cancer vaccines: Emerging concepts and developments Journal of Cellular Physiology. 186: 169-182. PMID 11169454 DOI: 10.1002/1097-4652(200102)186:2<169::Aid-Jcp1023>3.0.Co;2-H  0.465
2001 Revaz V, Benyacoub J, Kast WM, Schiller JT, De Grandi P, Nardelli-Haefliger D. Mucosal vaccination with a recombinant Salmonella typhimurium expressing human papillomavirus type 16 (HPV16) L1 virus-like particles (VLPs) or HPV16 VLPs purified from insect cells inhibits the growth of HPV16-expressing tumor cells in mice. Virology. 279: 354-60. PMID 11145916 DOI: 10.1006/Viro.2000.0717  0.467
2000 Muderspach L, Wilczynski S, Roman L, Bade L, Felix J, Small LA, Kast WM, Fascio G, Marty V, Weber J. A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive Clinical Cancer Research. 6: 3406-3416. PMID 10999722  0.381
2000 Ressing ME, van Driel WJ, Brandt RM, Kenter GG, de Jong JH, Bauknecht T, Fleuren GJ, Hoogerhout P, Offringa R, Sette A, Celis E, Grey H, Trimbos BJ, Kast WM, Melief CJ. Detection of T helper responses, but not of human papillomavirus-specific cytotoxic T lymphocyte responses, after peptide vaccination of patients with cervical carcinoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 255-66. PMID 10746552 DOI: 10.1097/00002371-200003000-00010  0.495
1999 Da Silva DM, Velders MP, Rudolf MP, Schiller JT, Kast WM. Papillomavirus virus-like particles as anticancer vaccines Current Opinion in Molecular Therapeutics. 1: 82-88. PMID 11249689  0.336
1999 Ressing ME, de Jong JH, Brandt RM, Drijfhout JW, Benckhuijsen WE, Schreuder GM, Offringa R, Kast WM, Melief CJ. Differential binding of viral peptides to HLA-A2 alleles. Implications for human papillomavirus type 16 E7 peptide-based vaccination against cervical carcinoma. European Journal of Immunology. 29: 1292-303. PMID 10229097 DOI: 10.1002/(Sici)1521-4141(199904)29:04<1292::Aid-Immu1292>3.0.Co;2-6  0.44
1999 Nieland JD, Da Silva DM, Velders MP, De Visser KE, Schiller JT, Müller M, Kast WM. Chimeric papillomavirus virus-like particles induce a murine self- antigen-specific protective and therapeutic antitumor immune response Journal of Cellular Biochemistry. 73: 145-152. PMID 10227378 DOI: 10.1002/(Sici)1097-4644(19990501)73:2<145::Aid-Jcb1>3.0.Co;2-5  0.418
1999 Rudolf MP, Nieland JD, DaSilva DM, Velders MP, Müller M, Greenstone HL, Schiller JT, Kast WM. Induction of HPV16 capsid protein-specific human T cell responses by virus-like particles Biological Chemistry. 380: 335-340. PMID 10223336  0.37
1998 Velders MP, Schreiber H, Kast WM. Active immunization against cancer cells: Impediments and advances Seminars in Oncology. 25: 697-706. PMID 9865683  0.344
1998 Vierboom MP, Feltkamp MC, Neisig A, Drijfhout JW, ter Schegget J, Neefjes JJ, Melief CJ, Kast WM. Peptide vaccination with an anchor-replaced CTL epitope protects against human papillomavirus type 16-induced tumors expressing the wild-type epitope. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 399-408. PMID 9807734 DOI: 10.1097/00002371-199811000-00001  0.318
1998 De Bruijn MLH, Greenstone HL, Vermeulen H, Melief CJM, Lowy DR, Schiller JT, Kast WM. L1-specific protection from tumor challenge elicited by HPV16 virus- like particles Virology. 250: 371-376. PMID 9792847 DOI: 10.1006/Viro.1998.9372  0.425
1998 Schoenberger SP, Jonges LE, Mooijaart RJ, Hartgers F, Toes RE, Kast WM, Melief CJ, Offringa R. Efficient direct priming of tumor-specific cytotoxic T lymphocyte in vivo by an engineered APC. Cancer Research. 58: 3094-100. PMID 9679976  0.367
1998 Toes RE, van der Voort EI, Schoenberger SP, Drijfhout JW, van Bloois L, Storm G, Kast WM, Offringa R, Melief CJ. Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 160: 4449-56. PMID 9574550  0.363
1998 Greenstone HL, Nieland JD, de Visser KE, De Bruijn ML, Kirnbauer R, Roden RB, Lowy DR, Kast WM, Schiller JT. Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model. Proceedings of the National Academy of Sciences of the United States of America. 95: 1800-5. PMID 9465097 DOI: 10.1073/Pnas.95.4.1800  0.474
1997 Visseren MJ, van der Burg SH, van der Voort EI, Brandt RM, Schrier PI, van der Bruggen P, Boon T, Melief CJ, Kast WM. Identification of HLA-A*0201-restricted CTL epitopes encoded by the tumor-specific MAGE-2 gene product. International Journal of Cancer. 73: 125-30. PMID 9334819 DOI: 10.1002/(Sici)1097-0215(19970926)73:1<125::Aid-Ijc19>3.0.Co;2-F  0.419
1997 Toes RE, Schoenberger SP, van der Voort EI, Kast WM, Hoeben RC, Melief CJ, Offringa R. Activation or frustration of anti-tumor responses by T-cell-based immune modulation. Seminars in Immunology. 9: 323-7. PMID 9327527 DOI: 10.1006/Smim.1997.0088  0.455
1997 Vierboom MP, Nijman HW, Offringa R, van der Voort EI, van Hall T, van den Broek L, Fleuren GJ, Kenemans P, Kast WM, Melief CJ. Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes. The Journal of Experimental Medicine. 186: 695-704. PMID 9271585 DOI: 10.1084/Jem.186.5.695  0.358
1997 Vennegoor CJGM, Nijman HW, Drijfhout JW, Vernie L, Verstraeten RA, Mensdorff-Pouilly Sv, Hilgers J, Verheijen RHM, Kast WM, Melief CJM, Kenemans P. Autoantibodies to p53 in ovarian cancer patients and healthy women: a comparison between whole p53 protein and 18-mer peptides for screening purposes Cancer Letters. 116: 93-101. PMID 9177463 DOI: 10.1016/S0304-3835(97)00168-7  0.323
1996 Ressing ME, Offringa R, Toes RE, Ossendorp F, de Jong JH, Brandt RM, Kast WM, Melief CJ. Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity. Immunotechnology : An International Journal of Immunological Engineering. 2: 241-51. PMID 9373306 DOI: 10.1016/S1380-2933(96)00057-7  0.529
1996 Van Driel WJ, Ressing ME, Brandt RMP, Toes REM, Fleuren GJ, Trimbos JB, Kast WM, Melief CJM. The current status of therapeutic HPV vaccine Annals of Medicine. 28: 471-477. PMID 9017105 DOI: 10.3109/07853899608999110  0.392
1996 Melief CJ, Offringa R, Toes RE, Kast WM. Peptide-based cancer vaccines. Current Opinion in Immunology. 8: 651-7. PMID 8902390 DOI: 10.1016/S0952-7915(96)80081-1  0.301
1996 Toes RE, Offringa R, Blom RJ, Melief CJ, Kast WM. Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction. Proceedings of the National Academy of Sciences of the United States of America. 93: 7855-60. PMID 8755566 DOI: 10.1073/pnas.93.15.7855  0.382
1996 Toes RE, Blom RJ, van der Voort E, Offringa R, Melief CJ, Kast WM. Protective antitumor immunity induced by immunization with completely allogeneic tumor cells. Cancer Research. 56: 3782-7. PMID 8706024  0.331
1996 Toes RE, Kast WM, Blom RJ, Bakker SC, Offringa R, Melief CJ. Efficient tumor eradication by adoptively transferred cytotoxic T-cell clones in allogeneic hosts. International Journal of Cancer. Journal International Du Cancer. 66: 686-91. PMID 8647633 DOI: 10.1002/(Sici)1097-0215(19960529)66:5<686::Aid-Ijc17>3.0.Co;2-2  0.386
1996 Toes RE, Blom RJ, Offringa R, Kast WM, Melief CJ. Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors. Journal of Immunology (Baltimore, Md. : 1950). 156: 3911-8. PMID 8621930  0.38
1996 Ressing ME, van Driel WJ, Celis E, Sette A, Brandt MP, Hartman M, Anholts JD, Schreuder GM, ter Harmsel WB, Fleuren GJ, Trimbos BJ, Kast WM, Melief CJ. Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A *0201-restricted E7-encoded epitope. Cancer Research. 56: 582-8. PMID 8564975  0.317
1996 Kast WM, Feltkamp MCW, Ressing ME, Vierboom MPM, Brandt RMP, Melief CJM. Cellular immunity against human papillomavirus associated cervical cancer Seminars in Virology. 7: 117-123. DOI: 10.1006/Smvy.1996.0015  0.44
1995 Feltkamp MCW, Vierboom MPM, Toes RM, Ossendorp F, Schegget Jt, Melief CJM, Kast WM. Competition inhibition of cytotoxic T-lymphocyte (CTL) lysis, a more sensitive method to identify candidate CTL epitopes than induction of antibody-detected MHC class I stabilization Immunology Letters. 47: 1-8. PMID 8537084 DOI: 10.1016/0165-2478(95)00052-7  0.34
1995 Van Elsas A, Nijman HW, Van der Minne CE, Mourer JS, Kast WM, Melief CJM, Schrier PI. Induction and characterization of cytotoxic T-lymphocytes recognizing a mutated p21ras peptide presented by HLA-A*0201 International Journal of Cancer. 61: 389-396. PMID 7729952 DOI: 10.1002/Ijc.2910610319  0.354
1995 Melief CJM, Kast WM. T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes Immunological Reviews. 167-177. PMID 7590825 DOI: 10.1111/J.1600-065X.1995.Tb00081.X  0.436
1995 Feltkamp MCW, Vreugdenhil GR, Vierboom MPM, Ras E, Van Der Burg SH, Ter Schegget J, Melief CJM, Kast WM. Cytotoxic T lymphocytes raised against a subdominant epitope offered as a synthetic peptide eradicate human papillomavirus type 16-induced tumors European Journal of Immunology. 25: 2638-2642. PMID 7589138 DOI: 10.1002/Eji.1830250935  0.465
1995 D'Amaro J, Houbiers JGA, Drijfhout JW, Brandt RMP, Schipper R, Bouwes Bavinck JN, Melief CJM, Kast WM. A computer program for predicting possible cytotoxic T lymphocyte epitopes based on HLA class I peptide-binding motifs Human Immunology. 43: 13-18. PMID 7558924 DOI: 10.1016/0198-8859(94)00153-H  0.352
1995 Ressing ME, Sette A, Brandt RMP, Ruppert J, Wentworth PA, Hartman M, Oseroff C, Grey HM, Melief CJM, Kast WM. Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA- A*0201-binding peptides Journal of Immunology. 154: 5934-5943. PMID 7538538  0.331
1994 Visseren MJW, Koot M, van der Voort EIH, Gravestein LA, Schoenmakers HJ, Kast WM, Zijlstra M, Melief CJM. Production of interleukin-2 by EL4 tumor cells induces natural killer cell- and T-cell-mediated immunity Journal of Immunotherapy. 15: 119-128. PMID 8136944  0.315
1994 Nijman HW, Burg SHVd, Vicrboom MPM, Houbiers JGA, Kast WM, Melief CJM. p53, a potential target for tumor-directed T cells Immunology Letters. 40: 171-178. PMID 8088874 DOI: 10.1016/0165-2478(94)90189-9  0.426
1994 Toes RE, Offringa R, Feltkamp MC, Visseren MJ, Schoenberger SP, Melief CJ, Kast WM. Tumor rejection antigens and tumor specific cytotoxic T lymphocytes. Behring Institute Mitteilungen. 72-86. PMID 7998917  0.338
1994 Feltkamp MCW, Vierboom MPM, Kast WM, Melief CJM. Efficient MHC class I-peptide binding is required but does not ensure MHC class I-restricted immunogenicity Molecular Immunology. 31: 1391-1401. PMID 7823965 DOI: 10.1016/0161-5890(94)90155-4  0.312
1993 Kast WM, Brandt RMP, Melief CJM. Strict peptide length is not required for the induction of cytotoxic T lymphocyte-mediated antiviral protection by peptide vaccination European Journal of Immunology. 23: 1189-1192. PMID 8386667 DOI: 10.1002/Eji.1830230534  0.391
1993 Houbiers JGA, Nijman HW, Van Der Burg SH, Drijfhout JW, Kenemans P, Van De Velde CJH, Brand A, Momburg F, Kast WM, Melief CJM. In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild-type p53 European Journal of Immunology. 23: 2072-2077. PMID 8370389 DOI: 10.1002/Eji.1830230905  0.413
1993 Ossevoort MA, Sijts AJ, van Veen KJ, Momburg F, Hämmerling GJ, Seelig A, Butcher GW, Howard JC, Kast WM, Melief CJ. Differential effect of transporter Tap 2 gene introduction into RMA-S cells on viral antigen processing. European Journal of Immunology. 23: 3082-8. PMID 8258321 DOI: 10.1002/Eji.1830231206  0.352
1993 Melief CJM, Kast WM. Potential immunogenicity of oncogene and tumor suppressor gene products Current Opinion in Immunology. 5: 709-713. PMID 8240732 DOI: 10.1016/0952-7915(93)90125-C  0.401
1993 Feltkamp MCW, Smits HL, Vierboom MPM, Mínnaar RP, De Jongh BM, Drijfhout JW, Ter Schegget J, Melief CJM, Kast WM. Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells European Journal of Immunology. 23: 2242-2249. PMID 7690326  0.387
1993 Nijman HW, Houbiers JGA, Vierboom MPM, Van der Burg SH, Drijfhout JW, D'Amaro J, Kenemans P, Melief CJM, Kast WM. Identification of peptide sequences that potentially trigger HLA-A2.1-restricted cytotoxic T lymphocytes European Journal of Immunology. 23: 1215-1219. PMID 7684681 DOI: 10.1002/Eji.1830230603  0.36
1993 Kast WM, Brandt RMP, Drijfhout JW, Melief CJM. Human leukocyte antigen-A2.1 restricted candidate cytotoxic t lymphocyte epitopes of human papillomavirus type 16 e6 and e7 proteins identified by using the processing-defective human cell line T2 Journal of Immunotherapy. 14: 115-120. PMID 7506573  0.315
1992 Sijts AJAM, De Bruijn MLH, Nieland JD, Kast WM, Melief CJM. Cytotoxic T lymphocytes against the antigen-processing-defective RMA-S tumor cell line European Journal of Immunology. 22: 1639-1642. PMID 1601045 DOI: 10.1002/Eji.1830220644  0.402
1992 De Bruijn MLH, Nieland JD, Schumacher TNM, Ploegh HL, Kast WM, Melief CJM. Mechanisms of induction of primary virus-specific cytotoxic T lymphocyte responses European Journal of Immunology. 22: 3013-3020. PMID 1425925 DOI: 10.1002/Eji.1830221137  0.416
1992 Melief CJM, Kast WM. Lessons from T cell responses to virus induced tumours for cancer eradication in general Cancer Surveys. 13: 81-99. PMID 1423326  0.329
1991 Melief CJM, Kast WM. Cytotoxic T lymphocyte therapy of cancer and tumor escape mechanisms Seminars in Cancer Biology. 2: 347-354. PMID 1773050  0.357
1991 Schumacher TN, De Bruijn ML, Vernie LN, Kast WM, Melief CJ, Neefjes JJ, Ploegh HL. Peptide selection by MHC class I molecules. Nature. 350: 703-6. PMID 1708852 DOI: 10.1038/350703A0  0.329
1991 De Bruijn MLH, Schumacher TNM, Nieland JD, Ploegh HL, Kast WM, Melief CJM. Peptide loading of empty major histocompatibility complex molecules on RMA-S cells allows the induction of primary cytotoxic T lymphocyte responses European Journal of Immunology. 21: 2963-2970. PMID 1660811 DOI: 10.1002/Eji.1830211210  0.37
1990 Twuyver Ev, Mooijaart RJD, Kast WM, Melief CJM, Waal LPd. Different requirements for the regulation of transplantation tolerance induction for allogeneic versus xenogeneic major histocompatibility complex antigens Human Immunology. 29: 220-228. PMID 2283336 DOI: 10.1016/0198-8859(90)90116-7  0.357
1990 Schumacher TN, Heemels MT, Neefjes JJ, Kast WM, Melief CJ, Ploegh HL. Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. Cell. 62: 563-7. PMID 2199065 DOI: 10.1016/0092-8674(90)90020-F  0.322
1989 Kast WM, Offringa R, Peters PJ, Voordouw AC, Meloen RH, van der Eb AJ, Melief CJ. Eradication of adenovirus E1-induced tumors by E1A-specific cytotoxic T lymphocytes. Cell. 59: 603-14. PMID 2555063 DOI: 10.1016/0092-8674(89)90006-8  0.371
1988 Kast WM, Van Twuyver E, Mooijaart RJD, Verveld M, Kamphuis AGA, Melief CJM, De Waal LP. Mechanism of skin allograft enhancement across and H-2 class I mutant difference. Evidence for involvement of veto cells European Journal of Immunology. 18: 2105-2108. PMID 2975604 DOI: 10.1002/Eji.1830181238  0.346
1988 Melief CJM, Boog CJP, Vasmel WLE, Boes J, Voordouw AC, Kast WM. Dendritic cells and antigen presentation in the regulation of cytotoxic T lymphocyte responses against viruses and transplantation antigens Annals of the New York Academy of Sciences. 532: 280-291. PMID 2845847 DOI: 10.1111/J.1749-6632.1988.Tb36346.X  0.377
1987 Kast WM, Voordouw AC, Leupers T, Visser JW, Melief CJ. Thymic immune response gene function in radiation chimeras reconstituted with purified hemopoietic stem cells European Journal of Immunology. 17: 471-475. PMID 3106065 DOI: 10.1002/Eji.1830170406  0.318
1985 Boog CJP, Kast WM, Marc Timmers HT, Boes J, De Waal LP, Melief CJM. Abolition of specific immune response defect by immunization with dendritic cells Nature. 318: 59-62. PMID 2932649 DOI: 10.1038/318059A0  0.359
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