Eric A. Sobie - Publications

Affiliations: 
Biophysics, Structural Biology, and Biomathematics Mount Sinai School of Medicine, New York, NY 
Area:
Physiology Biology, Pathology, Applied Mathematics

101 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gando I, Campana C, Tan RB, Cecchin F, Sobie EA, Coetzee WA. A distinct molecular mechanism by which phenytoin rescues a novel long QT 3 variant. Journal of Molecular and Cellular Cardiology. PMID 32339567 DOI: 10.1016/J.Yjmcc.2020.04.027  0.305
2020 Gong JQX, Susilo ME, Sher A, Musante CJ, Sobie EA. Quantitative analysis of variability in an integrated model of human ventricular electrophysiology and β-adrenergic signaling. Journal of Molecular and Cellular Cardiology. PMID 32330487 DOI: 10.1016/J.Yjmcc.2020.04.009  0.432
2019 Li Z, Mirams GR, Yoshinaga T, Ridder BJ, Han X, Chen JE, Stockbridge NL, Wisialowski TA, Damiano B, Severi S, Morissette P, Kowey PR, Holbrook M, Smith G, Rasmusson RL, ... ... Sobie EA, et al. General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy. Clinical Pharmacology and Therapeutics. PMID 31709525 DOI: 10.1002/Cpt.1647  0.362
2019 Jones DC, Sobie EA. Mechanistic Differences between Ca2+Sparks and Ca2Puffs Revealed Through Simulations of Heterogeneous Populations Biophysical Journal. 116: 401a. DOI: 10.1016/J.Bpj.2018.11.2167  0.309
2018 Varshneya M, Devenyi RA, Sobie EA. Slow Delayed Rectifier Current Protects Ventricular Myocytes From Arrhythmic Dynamics Across Multiple Species. Circulation. Arrhythmia and Electrophysiology. 11: e006558. PMID 30354408 DOI: 10.1161/Circep.118.006558  0.343
2018 Mora MT, Ferrero JM, Gomez JF, Sobie EA, Trenor B. Ca Cycling Impairment in Heart Failure Is Exacerbated by Fibrosis: Insights Gained From Mechanistic Simulations. Frontiers in Physiology. 9: 1194. PMID 30190684 DOI: 10.3389/Fphys.2018.01194  0.436
2018 Mayourian J, Sobie EA, Costa KD. An Introduction to Computational Modeling of Cardiac Electrophysiology and Arrhythmogenicity. Methods in Molecular Biology (Clifton, N.J.). 1816: 17-35. PMID 29987808 DOI: 10.1007/978-1-4939-8597-5_2  0.464
2018 Jones DC, Gong JQX, Sobie EA. A privileged role for neuronal Na channels in regulating ventricular [Ca] and arrhythmias. The Journal of General Physiology. PMID 29899058 DOI: 10.1085/Jgp.201812120  0.406
2018 Campana C, Gando I, Bianca Tan R, Cecchin F, Coetzee WA, Sobie EA. Population-Based Mathematical Modeling to Deduce Disease-Causing Cardiac Na+ Channel Gating Defects Biophysical Journal. 114: 634a-635a. DOI: 10.1016/J.Bpj.2017.11.3429  0.374
2017 Shim JV, Chun B, van Hasselt JGC, Birtwistle MR, Saucerman JJ, Sobie EA. Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics. Frontiers in Physiology. 8: 651. PMID 28951721 DOI: 10.3389/Fphys.2017.00651  0.366
2017 Sobie EA, Williams GSB, Lederer WJ. Ambiguous interactions between diastolic and SR Ca(2+) in the regulation of cardiac Ca(2+) release. The Journal of General Physiology. PMID 28798276 DOI: 10.1085/Jgp.201711814  0.4
2017 Mayourian J, Cashman TJ, Ceholski DK, Johnson BV, Sachs D, Kaji DA, Sahoo S, Hare JM, Hajjar RJ, Sobie EA, Costa KD. Experimental and Computational Insight into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity. Circulation Research. PMID 28642329 DOI: 10.1161/Circresaha.117.310796  0.427
2017 Mayourian J, Cashman TJ, Johnson BV, Sachs DM, Kaji DA, Sobie EA, Costa KD. Human Mesenchymal Stem Cell Paracrine Signaling Counteracts Heterocellular Coupling Effects on Cardiac Contractility and Arrhythomgenicity Biophysical Journal. 112: 162a. DOI: 10.1016/J.Bpj.2016.11.890  0.437
2017 Gong J, Thompson WC, Musante CJ, Sobie EA. An Integrated Model of Human Beta-Adrenergic Signaling and Ventricular Electrophysiology Reveals Contributors to Positive Inotropy Biophysical Journal. 112: 403a-404a. DOI: 10.1016/J.Bpj.2016.11.2185  0.407
2016 Devenyi RA, Ortega FA, Groenendaal W, Krogh-Madsen T, Christini DJ, Sobie EA. Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility. The Journal of Physiology. PMID 27779762 DOI: 10.1113/JP273191  0.344
2016 Mayourian J, Savizky RM, Sobie EA, Costa KD. Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes. Plos Computational Biology. 12: e1005014. PMID 27454812 DOI: 10.1371/Journal.Pcbi.1005014  0.406
2016 Lee YS, Hwang M, Song JS, Li C, Joung B, Sobie EA, Pak HN. The Contribution of Ionic Currents to Rate-Dependent Action Potential Duration and Pattern of Reentry in a Mathematical Model of Human Atrial Fibrillation. Plos One. 11: e0150779. PMID 26964092 DOI: 10.1371/Journal.Pone.0150779  0.418
2016 Cummins Lancaster M, Sobie EA. Improved prediction of drug-induced Torsades de Pointes through simulations of dynamics and machine learning algorithms. Clinical Pharmacology and Therapeutics. PMID 26950176 DOI: 10.1002/Cpt.367  0.387
2016 Gong J, Sobie EA. Quantitative Predictions of Adult Human Drug Effects from Stem Cell-Derived Myocyte Physiology Biophysical Journal. 110: 586a. DOI: 10.1016/J.Bpj.2015.11.3130  0.374
2016 Shim JV, Birtwistle MR, Iyengar R, Sobie EA. Integrated Analysis for Quantitative Predictions of Drug Induced Cardiotoxicity Biophysical Journal. 110: 476a-477a. DOI: 10.1016/J.Bpj.2015.11.2549  0.367
2016 Mayourian J, Savizky RM, Sobie EA, Costa KD. Modeling Electrophysiological Interactions between Mesenchymal Stem Cells and Cardiomyocytes for Improved Cell Delivery Cardiotherapeutics Biophysical Journal. 110: 271a. DOI: 10.1016/J.Bpj.2015.11.1475  0.43
2015 Krogh-Madsen T, Sobie EA, Christini DJ. Improving cardiomyocyte model fidelity and utility via dynamic electrophysiology protocols and optimization algorithms. The Journal of Physiology. PMID 26661516 DOI: 10.1113/Jp270618  0.411
2015 Devenyi RA, Sobie EA. There and back again: Iterating between population-based modeling and experiments reveals surprising regulation of calcium transients in rat cardiac myocytes. Journal of Molecular and Cellular Cardiology. PMID 26235057 DOI: 10.1016/j.yjmcc.2015.07.016  0.36
2015 Poláková E, Illaste A, Niggli E, Sobie EA. Maximal acceleration of Ca2+ release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes. The Journal of Physiology. 593: 1495-507. PMID 25772298 DOI: 10.1113/Jphysiol.2014.278051  0.392
2015 Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, ... ... Sobie EA, et al. Na+ channel function, regulation, structure, trafficking and sequestration. The Journal of Physiology. 593: 1347-60. PMID 25772290 DOI: 10.1113/Jphysiol.2014.281428  0.336
2015 Wang X, Weinberg SH, Hao Y, Sobie EA, Smith GD. Calcium homeostasis in a local/global whole cell model of permeabilized ventricular myocytes with a Langevin description of stochastic calcium release. American Journal of Physiology. Heart and Circulatory Physiology. 308: H510-23. PMID 25485896 DOI: 10.1152/Ajpheart.00296.2014  0.631
2015 Cummins MA, Sobie EA. A Novel Classification Method with Superior Prediction of Drug Arrhythmia Risk Biophysical Journal. 108: 111a. DOI: 10.1016/J.Bpj.2014.11.628  0.403
2014 Núñez-Acosta E, Sobie EA. The ryanodine receptor patchwork: knitting calcium spark dynamics. Biophysical Journal. 107: 2749-50. PMID 25517141 DOI: 10.1016/J.Bpj.2014.10.068  0.422
2014 Josowitz R, Lu J, Falce C, D'Souza SL, Wu M, Cohen N, Dubois NC, Zhao Y, Sobie EA, Fishman GI, Gelb BD. Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression. Plos One. 9: e101316. PMID 25010565 DOI: 10.1371/Journal.Pone.0101316  0.317
2014 Cummins MA, Dalal PJ, Bugana M, Severi S, Sobie EA. Comprehensive analyses of ventricular myocyte models identify targets exhibiting favorable rate dependence. Plos Computational Biology. 10: e1003543. PMID 24675446 DOI: 10.1371/Journal.Pcbi.1003543  0.399
2014 Cummins MA, Dalal P, Bugana M, Severi S, Sobie E. Overcoming Reverse Rate Dependence in Ventricular Cell Models Biophysical Journal. 106: 644a. DOI: 10.1016/J.Bpj.2013.11.3563  0.399
2014 Illaste A, Polakova E, Niggli E, Sobie EA. Activity of Both PKA and Camkii is Required for Maximal RyR Sensitivity Under Beta-Adrenergic Stimulation Biophysical Journal. 106: 431a. DOI: 10.1016/J.Bpj.2013.11.2426  0.358
2013 Lee P, Sobie EA, Peskin CS. Computer simulation of voltage sensitive calcium ion channels in a dendritic spine. Journal of Theoretical Biology. 338: 87-93. PMID 23999286 DOI: 10.1016/J.Jtbi.2013.08.019  0.321
2013 Lee YS, Liu OZ, Hwang HS, Knollmann BC, Sobie EA. Parameter sensitivity analysis of stochastic models provides insights into cardiac calcium sparks. Biophysical Journal. 104: 1142-50. PMID 23473497 DOI: 10.1016/J.Bpj.2012.12.055  0.427
2013 Poláková E, Sobie EA. Alterations in T-tubule and dyad structure in heart disease: challenges and opportunities for computational analyses. Cardiovascular Research. 98: 233-9. PMID 23396602 DOI: 10.1093/Cvr/Cvt026  0.431
2013 Lee YS, Liu OZ, Sobie EA. Decoding myocardial Ca²⁺ signals across multiple spatial scales: a role for sensitivity analysis. Journal of Molecular and Cellular Cardiology. 58: 92-9. PMID 23026728 DOI: 10.1016/J.Yjmcc.2012.09.009  0.45
2013 Polakova E, Illaste A, Niggli E, Sobie EA. Factors Influencing Ca2+ Spark Refractoriness in Mouse Biophysical Journal. 104: 438a. DOI: 10.1016/J.Bpj.2012.11.2435  0.39
2013 Wang X, Hao Y, Weinberg SH, Sobie EA, Smith GD. Analysis of Spark Versus Non-Spark Mediated SR Calcium Leak using a Langevin Description of Stochastic Calcium Release Biophysical Journal. 104: 438a. DOI: 10.1016/J.Bpj.2012.11.2432  0.592
2013 Lee Y, Delmar M, Sobie EA. Quantitative Contributions to Electrical Propagation in 1D Cable Model Biophysical Journal. 104: 297a. DOI: 10.1016/J.Bpj.2012.11.1656  0.397
2013 Giovannini A, Severi S, Sobie E. Parametric Sensitivity Analysis of the Most Recent Computational Models of Rabbit Cardiac Pacemaking Biophysical Journal. 104: 296a. DOI: 10.1016/J.Bpj.2012.11.1652  0.428
2012 LaRocca TJ, Fabris F, Chen J, Benhayon D, Zhang S, McCollum L, Schecter AD, Cheung JY, Sobie EA, Hajjar RJ, Lebeche D. Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway. American Journal of Physiology. Heart and Circulatory Physiology. 303: H353-67. PMID 22610174 DOI: 10.1152/Ajpheart.01198.2011  0.411
2012 Sarkar AX, Christini DJ, Sobie EA. Exploiting mathematical models to illuminate electrophysiological variability between individuals. The Journal of Physiology. 590: 2555-67. PMID 22495591 DOI: 10.1113/Jphysiol.2011.223313  0.609
2012 Liu OZ, Lederer WJ, Sobie EA. Does the Goldilocks Principle apply to calcium release restitution in heart cells? Journal of Molecular and Cellular Cardiology. 52: 3-6. PMID 22056316 DOI: 10.1016/J.Yjmcc.2011.10.014  0.419
2012 Sobie EA, Lederer WJ. Dynamic local changes in sarcoplasmic reticulum calcium: physiological and pathophysiological roles. Journal of Molecular and Cellular Cardiology. 52: 304-11. PMID 21767546 DOI: 10.1016/J.Yjmcc.2011.06.024  0.364
2012 Lee Y, Liu O, Knollmann BC, Sobie EA. Parameter Sensitivity Analysis of a Stochastic Ca2+ Spark Model using Novel Computational Methods Biophysical Journal. 102: 100a-101a. DOI: 10.1016/J.Bpj.2011.11.570  0.392
2012 McGovern KR, Sobie EA. Predicting the Effects of Nonspecific Channel Blocking Drugs has Variable Success Rates Between Different Ventricular Myocyte Action Potential Models Biophysical Journal. 102: 541a. DOI: 10.1016/J.Bpj.2011.11.2954  0.339
2011 Sobie EA, Sarkar AX. Regression methods for parameter sensitivity analysis: applications to cardiac arrhythmia mechanisms. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 4657-60. PMID 22255376 DOI: 10.1109/IEMBS.2011.6091153  0.573
2011 Bao L, Kefaloyianni E, Lader J, Hong M, Morley G, Fishman GI, Sobie EA, Coetzee WA. Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system. Circulation. Arrhythmia and Electrophysiology. 4: 926-35. PMID 21984445 DOI: 10.1161/Circep.111.964643  0.354
2011 Sobie EA. Computational modeling of the cell cycle. Science Signaling. 4: tr11. PMID 21954292 DOI: 10.1126/Scisignal.2001985  0.319
2011 Williams GS, Chikando AC, Tuan HT, Sobie EA, Lederer WJ, Jafri MS. Dynamics of calcium sparks and calcium leak in the heart. Biophysical Journal. 101: 1287-96. PMID 21943409 DOI: 10.1016/J.Bpj.2011.07.021  0.418
2011 Sarkar AX, Sobie EA. Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysis. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 1749-55. PMID 21699863 DOI: 10.1016/J.Hrthm.2011.05.023  0.566
2011 Ramay HR, Liu OZ, Sobie EA. Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity. Cardiovascular Research. 91: 598-605. PMID 21613275 DOI: 10.1093/Cvr/Cvr143  0.413
2011 Sobie EA. Getting heart cells on the same wavelength: infrared triggering of Ca2+ transients in cardiac myocytes. The Journal of Physiology. 589: 1243-4. PMID 21486850 DOI: 10.1113/Jphysiol.2011.205906  0.411
2011 Dhandapany PS, Fabris F, Tonk R, Illaste A, Karakikes I, Sorourian M, Sheng J, Hajjar RJ, Tartaglia M, Sobie EA, Lebeche D, Gelb BD. Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes. Journal of Molecular and Cellular Cardiology. 51: 4-15. PMID 21440552 DOI: 10.1016/J.Yjmcc.2011.03.001  0.353
2011 Lee YS, Dun W, Boyden PA, Sobie EA. Complex and rate-dependent beat-to-beat variations in Ca2+ transients of canine Purkinje cells. Journal of Molecular and Cellular Cardiology. 50: 662-9. PMID 21232541 DOI: 10.1016/J.Yjmcc.2010.12.023  0.391
2011 Chung CY, Bien H, Sobie EA, Dasari V, McKinnon D, Rosati B, Entcheva E. Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self-organization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 851-62. PMID 21084696 DOI: 10.1096/Fj.10-168625  0.675
2011 Liu O, Ramay H, Sobie EA. B-Adrenergic Stimulation Accelerates Local Recovery of Cardiac Ca2+ Release Biophysical Journal. 100: 559a. DOI: 10.1016/J.Bpj.2010.12.3249  0.395
2011 Williams GS, Chikando AC, Lederer WJ, Sobie EA, Tuan HM, Jafri MS. Ca2+ Leak and Ca2+ Sparks in Mammalian Heart: Insights from a Computational Model Biophysical Journal. 100: 557a. DOI: 10.1016/J.Bpj.2010.12.3238  0.421
2011 Sarkar AX, Sobie EA. Using Regression-Based Model Analysis to Reconstruct and Predict Redundant Experimental Measurements Biophysical Journal. 100: 437a. DOI: 10.1016/J.Bpj.2010.12.2576  0.541
2011 McGovern KR, Sarkar AX, Sobie EA. In Silico Modeling of Changes to Ventricular Myocyte Action Potential Morphology Caused by Pharmacological Agents Biophysical Journal. 100: 159a. DOI: 10.1016/J.Bpj.2010.12.1084  0.587
2010 Hartman JM, Sobie EA, Smith GD. Spontaneous Ca2+ sparks and Ca2+ homeostasis in a minimal model of permeabilized ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1996-2008. PMID 20852058 DOI: 10.1152/Ajpheart.00293.2010  0.388
2010 Sarkar AX, Sobie EA. Regression analysis for constraining free parameters in electrophysiological models of cardiac cells. Plos Computational Biology. 6: e1000914. PMID 20824123 DOI: 10.1371/Journal.Pcbi.1000914  0.573
2010 Josephson IR, Guia A, Sobie EA, Lederer WJ, Lakatta EG, Stern MD. Physiologic gating properties of unitary cardiac L-type Ca2+ channels. Biochemical and Biophysical Research Communications. 396: 763-6. PMID 20457123 DOI: 10.1016/J.Bbrc.2010.05.016  0.422
2010 Williams GS, Smith GD, Sobie EA, Jafri MS. Models of cardiac excitation-contraction coupling in ventricular myocytes. Mathematical Biosciences. 226: 1-15. PMID 20346962 DOI: 10.1016/J.Mbs.2010.03.005  0.361
2010 Hartman JM, Sobie EA, Smith GD. Calcium Sparks and Homeostasis in a Minimal Model of Local and Global Calcium Responses in Quiescent Ventricular Myocytes Biophysical Journal. 98: 105a. DOI: 10.1016/J.Bpj.2009.12.585  0.383
2010 Lee Y, Dun W, Boyden PA, Sobie EA. Canine Purkinje Cells Exhibit Complex and Rate-Dependent Beat-To-Beat Variations in Calcium Transients Biophysical Journal. 98: 103a. DOI: 10.1016/J.Bpj.2009.12.577  0.398
2010 Fabris F, Illaste A, Park M, Adler ED, Sobie EA. Mechanisms Underlying Spontaneous Beating in Human Embryonic Stem Cell-Derived Cardiac Myocytes Biophysical Journal. 98: 99a. DOI: 10.1016/J.Bpj.2009.12.555  0.415
2010 Sarkar AX, McGovern K, Sobie EA. Understanding Pro-Arrhythmic Effects of Drugs using Computational Models and Parameter Sensitivity Analysis Biophysical Journal. 98: 530a. DOI: 10.1016/J.Bpj.2009.12.2876  0.602
2009 Sobie EA. Parameter sensitivity analysis in electrophysiological models using multivariable regression. Biophysical Journal. 96: 1264-74. PMID 19217846 DOI: 10.1016/J.Bpj.2008.10.056  0.373
2009 Sobie EA, Ramay HR. Excitation-contraction coupling gain in ventricular myocytes: insights from a parsimonious model. The Journal of Physiology. 587: 1293-9. PMID 19153162 DOI: 10.1113/Jphysiol.2008.163915  0.466
2009 Sobie EA, Wehrens XH. Computational and experimental models of Ca2+-dependent arrhythmias Drug Discovery Today: Disease Models. 6: 57-61. DOI: 10.1016/J.Ddmod.2010.04.002  0.481
2009 Lehnart SE, Ward CW, Sobie EA, Lederer W. Mutant Ryanodine Receptor-dependent Calcium Leak, RyR2 Open Probability, Calcium Sparks And Cardiac Arrhythmogenesis Biophysical Journal. 96: 550a. DOI: 10.1016/J.Bpj.2008.12.2981  0.422
2009 Williams GS, Huertas MA, Sobie EA, Smith GD, Jafri MS. A Local Control Model for Cardiac Excitation-Contraction Coupling in Rat Ventricular Myocytes: Insights into Dynamic Phenomena involving Calcium Release Biophysical Journal. 96: 518a. DOI: 10.1016/J.Bpj.2008.12.2667  0.44
2009 Fabris FJ, Noel O, Sobie EA. Changes In Cytosolic Ca2+ Have Greater Effects On SR Ca2+ Leak Than Changes In SR Ca2+ Biophysical Journal. 96: 277a. DOI: 10.1016/J.Bpj.2008.12.1369  0.339
2009 Ramay HR, Sobie EA. Ca2+ Spark Restitution In Ventricular Myocytes With Modified Ryanodine Receptor Gating Biophysical Journal. 96: 21a. DOI: 10.1016/J.Bpj.2008.12.1013  0.369
2008 Bridge JH, Torres NS, Sobie EA. New insights into the structure and function of couplons. The Journal of Physiology. 586: 3735. PMID 18708492 DOI: 10.1113/Jphysiol.2008.159509  0.366
2008 Lipsky R, Potts EM, Tarzami ST, Puckerin AA, Stocks J, Schecter AD, Sobie EA, Akar FG, Diversé-Pierluissi MA. beta-Adrenergic receptor activation induces internalization of cardiac Cav1.2 channel complexes through a beta-arrestin 1-mediated pathway. The Journal of Biological Chemistry. 283: 17221-6. PMID 18458091 DOI: 10.1074/Jbc.C800061200  0.393
2008 Wang LJ, Sobie EA. Mathematical model of the neonatal mouse ventricular action potential. American Journal of Physiology. Heart and Circulatory Physiology. 294: H2565-75. PMID 18408122 DOI: 10.1152/Ajpheart.01376.2007  0.394
2008 Sobie EA, Cannell MB, Bridge JH. Allosteric activation of Na+-Ca2+ exchange by L-type Ca2+ current augments the trigger flux for SR Ca2+ release in ventricular myocytes. Biophysical Journal. 94: L54-6. PMID 18223001 DOI: 10.1529/Biophysj.107.127878  0.371
2007 Ni J, Auston DA, Freilich DA, Muralidharan S, Sobie EA, Kao JP. Photochemical gating of intracellular Ca2+ release channels. Journal of the American Chemical Society. 129: 5316-7. PMID 17425315 DOI: 10.1021/Ja069361Q  0.389
2007 Sobie EA, Kao JP, Lederer WJ. Novel approach to real-time flash photolysis and confocal [Ca2+] imaging. Pflã¼Gers Archiv : European Journal of Physiology. 454: 663-73. PMID 17323075 DOI: 10.1007/S00424-007-0229-Z  0.348
2007 Williams GS, Huertas MA, Sobie EA, Jafri MS, Smith GD. A probability density approach to modeling local control of calcium-induced calcium release in cardiac myocytes. Biophysical Journal. 92: 2311-28. PMID 17237200 DOI: 10.1529/Biophysj.106.099861  0.406
2007 Collis LP, Meyers MB, Zhang J, Phoon CK, Sobie EA, Coetzee WA, Fishman GI. Expression of a sorcin missense mutation in the heart modulates excitation-contraction coupling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 475-87. PMID 17130302 DOI: 10.1096/Fj.06-6292Com  0.445
2006 Sobie EA, Song LS, Lederer WJ. Restitution of Ca(2+) release and vulnerability to arrhythmias. Journal of Cardiovascular Electrophysiology. 17: S64-S70. PMID 16686684 DOI: 10.1111/J.1540-8167.2006.00385.X  0.436
2006 Song LS, Sobie EA, McCulle S, Lederer WJ, Balke CW, Cheng H. Orphaned ryanodine receptors in the failing heart. Proceedings of the National Academy of Sciences of the United States of America. 103: 4305-10. PMID 16537526 DOI: 10.1073/Pnas.0509324103  0.443
2006 Sobie EA, Guatimosim S, Gómez-Viquez L, Song LS, Hartmann H, Saleet Jafri M, Lederer WJ. The Ca 2+ leak paradox and rogue ryanodine receptors: SR Ca 2+ efflux theory and practice. Progress in Biophysics and Molecular Biology. 90: 172-85. PMID 16326215 DOI: 10.1016/J.Pbiomolbio.2005.06.010  0.386
2005 Song LS, Guatimosim S, Gómez-Viquez L, Sobie EA, Ziman A, Hartmann H, Lederer WJ. Calcium biology of the transverse tubules in heart. Annals of the New York Academy of Sciences. 1047: 99-111. PMID 16093488 DOI: 10.1196/Annals.1341.009  0.397
2005 Knot HJ, Laher I, Sobie EA, Guatimosim S, Gomez-Viquez L, Hartmann H, Song LS, Lederer WJ, Graier WF, Malli R, Frieden M, Petersen OH. Twenty years of calcium imaging: cell physiology to dye for. Molecular Interventions. 5: 112-27. PMID 15821159 DOI: 10.1124/Mi.5.2.8  0.38
2005 Sobie EA, Song LS, Lederer WJ. Local recovery of Ca2+ release in rat ventricular myocytes. The Journal of Physiology. 565: 441-7. PMID 15817631 DOI: 10.1113/Jphysiol.2005.086496  0.393
2002 Guatimosim S, Dilly K, Santana LF, Saleet Jafri M, Sobie EA, Lederer WJ. Local Ca(2+) signaling and EC coupling in heart: Ca(2+) sparks and the regulation of the [Ca(2+)](i) transient. Journal of Molecular and Cellular Cardiology. 34: 941-50. PMID 12234764 DOI: 10.1006/Jmcc.2002.2032  0.401
2002 Sobie EA, Dilly KW, dos Santos Cruz J, Lederer WJ, Jafri MS. Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release. Biophysical Journal. 83: 59-78. PMID 12080100 DOI: 10.1016/S0006-3495(02)75149-7  0.39
2001 Guatimosim S, Sobie EA, dos Santos Cruz J, Martin LA, Lederer WJ. Molecular identification of a TTX-sensitive Ca(2+) current. American Journal of Physiology. Cell Physiology. 280: C1327-39. PMID 11287346 DOI: 10.1152/Ajpcell.2001.280.5.C1327  0.431
1999 Cheng DK, Tung L, Sobie EA. Nonuniform responses of transmembrane potential during electric field stimulation of single cardiac cells. The American Journal of Physiology. 277: H351-62. PMID 10409215 DOI: 10.1152/Ajpheart.1999.277.1.H351  0.579
1999 Susil RC, Sobie EA, Tung L. Separation between virtual sources modifies the response of cardiac tissue to field stimulation. Journal of Cardiovascular Electrophysiology. 10: 715-27. PMID 10355927 DOI: 10.1111/J.1540-8167.1999.Tb00248.X  0.532
1998 Riemer TL, Sobie EA, Tung L. Stretch-induced changes in arrhythmogenesis and excitability in experimentally based heart cell models. American Journal of Physiology. Heart and Circulatory Physiology. 275: H431-H442. PMID 29591568 DOI: 10.1152/ajpheart.1998.275.2.H431  0.747
1998 Sobie EA, Tung L. Postshock potential gradients and dispersion of repolarization in cells stimulated with monophasic and biphasic waveforms Journal of Cardiovascular Electrophysiology. 9: 743-756. PMID 9684722 DOI: 10.1111/J.1540-8167.1998.Tb00961.X  0.585
1998 Riemer TL, Sobie EA, Tung L. Stretch-induced changes in arrhythmogenesis and excitability in experimentally based heart cell models. The American Journal of Physiology. 275: H431-42. PMID 9683430 DOI: 10.1152/Ajpheart.1998.275.2.H431  0.743
1997 Sobie EA, Susil RC, Tung L. A generalized activating function for predicting virtual electrodes in cardiac tissue. Biophysical Journal. 73: 1410-23. PMID 9284308 DOI: 10.1016/S0006-3495(97)78173-6  0.583
1997 Fishler MG, Sobie EA, Tung L, Thakor NV. Modeling the interaction between propagating cardiac waves and monophasic and biphasic field stimuli: the importance of the induced spatial excitatory response. Journal of Cardiovascular Electrophysiology. 7: 1183-96. PMID 8985807 DOI: 10.1111/J.1540-8167.1996.Tb00497.X  0.595
1996 Fishler MG, Sobie EA, Thakor NV, Tung L. Mechanisms of cardiac cell excitation with premature monophasic and biphasic field stimuli: a model study. Biophysical Journal. 70: 1347-62. PMID 8785290 DOI: 10.1016/S0006-3495(96)79692-3  0.591
1996 Fishler MG, Sobie EA, Tung L, Thakor NV. Cardiac responses to premature monophasic and biphasic field stimuli. Results from cell and tissue modeling studies. Journal of Electrocardiology. 174-9. PMID 8656107 DOI: 10.1016/S0022-0736(95)80052-2  0.563
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