| Year |
Citation |
Score |
| 2024 |
Hoque MM, Gbadegoye JO, Hassan FO, Raafat A, Lebeche D. Cardiac fibrogenesis: an immuno-metabolic perspective. Frontiers in Physiology. 15: 1336551. PMID 38577624 DOI: 10.3389/fphys.2024.1336551 |
0.322 |
|
| 2023 |
Gu Q, Orgil BO, Bajpai AK, Chen Y, Ashbrook DG, Starlard-Davenport A, Towbin JA, Lebeche D, Purevjav E, Sheng H, Lu L. Expression Levels of the Gene in the Heart Are Highly Associated with Cardiac and Glucose Metabolism-Related Phenotypes and Functional Pathways. International Journal of Molecular Sciences. 24. PMID 37628941 DOI: 10.3390/ijms241612759 |
0.368 |
|
| 2023 |
Majid A, Hassan FO, Hoque MM, Gbadegoye JO, Lebeche D. Bioactive Compounds and Cardiac Fibrosis: Current Insight and Future Prospect. Journal of Cardiovascular Development and Disease. 10. PMID 37504569 DOI: 10.3390/jcdd10070313 |
0.318 |
|
| 2022 |
Cai X, Allison MA, Ambale-Venkatesh B, Jorgensen NW, Lima JAC, Muse ED, McClelland RL, Shea S, Lebeche D. Resistin and risks of incident heart failure subtypes and cardiac fibrosis: the Multi-Ethnic Study of Atherosclerosis. Esc Heart Failure. PMID 35860859 DOI: 10.1002/ehf2.14064 |
0.671 |
|
| 2021 |
Kaur K, Hadas Y, Kurian AA, Żak MM, Yoo J, Mahmood A, Girard H, Komargodski R, Io T, Santini MP, Sultana N, Kabir Sharkar MT, Magadum A, Fargnoli A, Yoon S, ... ... Lebeche D, et al. Direct Reprogramming Induces Vascular Regeneration Post Muscle Ischemic Injury. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34332145 DOI: 10.1016/j.ymthe.2021.07.014 |
0.514 |
|
| 2021 |
Zhao B, Bouchareb R, Lebeche D. Resistin deletion protects against heart failure injury by targeting DNA damage response. Cardiovascular Research. PMID 34324657 DOI: 10.1093/cvr/cvab234 |
0.311 |
|
| 2021 |
Magadum A, Singh N, Kurian AA, Sharkar MTK, Sultana N, Chepurko E, Kaur K, Żak MM, Hadas Y, Lebeche D, Sahoo S, Hajjar R, Zangi L. Therapeutic Delivery of Pip4k2c-Modified mRNA Attenuates Cardiac Hypertrophy and Fibrosis in the Failing Heart. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: 2004661. PMID 34026458 DOI: 10.1002/advs.202004661 |
0.548 |
|
| 2021 |
Singh R, Kaundal RK, Zhao B, Bouchareb R, Lebeche D. Resistin induces cardiac fibroblast-myofibroblast differentiation through JAK/STAT3 and JNK/c-Jun signaling. Pharmacological Research. 105414. PMID 33524540 DOI: 10.1016/j.phrs.2020.105414 |
0.345 |
|
| 2021 |
Dhandapany PS, Kang S, Kashyap DK, Rajagopal R, Sundaresan NR, Singh R, Thangaraj K, Jayaprakash S, Manjunath CN, Shenthar J, Lebeche D. Adiponectin receptor 1 variants contribute to hypertrophic cardiomyopathy that can be reversed by rapamycin. Science Advances. 7. PMID 33523960 DOI: 10.1126/sciadv.abb3991 |
0.306 |
|
| 2020 |
Bouchareb R, Katz M, Saadallah N, Sassi Y, Ali S, Lebeche D. Boron improves cardiac contractility and fibrotic remodeling following myocardial infarction injury. Scientific Reports. 10: 17138. PMID 33051505 DOI: 10.1038/s41598-020-73864-w |
0.414 |
|
| 2018 |
Singh R, Moreno P, Hajjar RJ, Lebeche D. A role for calcium in resistin transcriptional activation in diabetic hearts. Scientific Reports. 8: 15633. PMID 30353146 DOI: 10.1038/s41598-018-34112-4 |
0.539 |
|
| 2018 |
Mathiyalagan P, Adamiak M, Mayourian J, Sassi Y, Liang Y, Agarwal N, Jha D, Zhang S, Kohlbrenner E, Chepurko E, Chen J, Trivieri MG, Singh R, Bouchareb R, Fish K, ... ... Lebeche D, et al. FTO-Dependent m6A Regulates Cardiac Function During Remodeling and Repair. Circulation. PMID 29997116 DOI: 10.1161/CIRCULATIONAHA.118.033794 |
0.605 |
|
| 2018 |
Rodriguez P, Sassi Y, Troncone L, Benard L, Ishikawa K, Gordon RE, Lamas S, Laborda J, Hajjar RJ, Lebeche D. Deletion of delta-like 1 homologue accelerates fibroblast-myofibroblast differentiation and induces myocardial fibrosis. European Heart Journal. PMID 29668883 DOI: 10.1093/eurheartj/ehy188 |
0.551 |
|
| 2018 |
Kawai H, Chaudhry F, Shekhar A, Petrov A, Nakahara T, Tanimoto T, Kim D, Chen J, Lebeche D, Blankenberg FG, Pak KY, Kolodgie FD, Virmani R, Sengupta P, Narula N, et al. Molecular Imaging of Apoptosis in Ischemia Reperfusion Injury With Radiolabeled Duramycin Targeting Phosphatidylethanolamine: Effective Target Uptake and Reduced Nontarget Organ Radiation Burden. Jacc. Cardiovascular Imaging. PMID 29454770 DOI: 10.1016/j.jcmg.2017.11.037 |
0.393 |
|
| 2017 |
Bidwell PA, Liu GS, Nagarajan N, Lam CK, Haghighi K, Gardner G, Cai WF, Zhao W, Mugge L, Vafiadaki E, Sanoudou D, Rubinstein J, Lebeche D, Hajjar R, Sadoshima J, et al. HAX-1 regulates SERCA2a oxidation and degradation. Journal of Molecular and Cellular Cardiology. PMID 29169992 DOI: 10.1016/J.Yjmcc.2017.11.014 |
0.526 |
|
| 2017 |
Hammoudi N, Jeong D, Singh R, Farhat A, Komajda M, Mayoux E, Hajjar R, Lebeche D. Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes. Cardiovascular Drugs and Therapy. PMID 28643218 DOI: 10.1007/s10557-017-6734-1 |
0.529 |
|
| 2017 |
Lebeche D, Hajjar R. Candesartan abrogates G protein-coupled receptors agonist-induced MAPK activation and cardiac myocyte hypertrophy. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 2: S154-S161. PMID 28095237 DOI: 10.1177/14703203010020012701 |
0.47 |
|
| 2016 |
Chen J, Hammoudi N, Benard L, Ceholski DK, Zhang S, Lebeche D, Hajjar RJ. The Probability of Inconstancy in Assessment of Cardiac Function Post-Myocardial Infarction in Mice. Cardiovascular Pharmacology: Open Access. 5. PMID 27917392 |
0.516 |
|
| 2015 |
Kang S, Dahl R, Hsieh W, Shin AC, Zsebo KM, Buettner C, Hajjar RJ, Lebeche D. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders. The Journal of Biological Chemistry. PMID 26702054 DOI: 10.1074/Jbc.M115.705012 |
0.45 |
|
| 2015 |
Ramos-Kuri M, Rapti K, Mehel H, Zhang S, Dhandapany PS, Liang L, García-Carrancá A, Bobe R, Fischmeister R, Adnot S, Lebeche D, Hajjar RJ, Lipskaia L, Chemaly ER. Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy. Biochimica Et Biophysica Acta. PMID 26260012 DOI: 10.1016/j.bbamcr.2015.08.006 |
0.434 |
|
| 2015 |
Cai WF, Liu GS, Lam CK, Florea S, Qian J, Zhao W, Pritchard T, Haghighi K, Lebeche D, Lu LJ, Deng J, Fan GC, Hajjar RJ, Kranias EG. Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility. European Journal of Heart Failure. 17: 782-93. PMID 26177627 DOI: 10.1002/Ejhf.323 |
0.515 |
|
| 2014 |
Dhandapany PS, Razzaque MA, Muthusami U, Kunnoth S, Edwards JJ, Mulero-Navarro S, Riess I, Pardo S, Sheng J, Rani DS, Rani B, Govindaraj P, Flex E, Yokota T, Furutani M, ... ... Lebeche D, et al. RAF1 mutations in childhood-onset dilated cardiomyopathy. Nature Genetics. 46: 635-9. PMID 24777450 DOI: 10.1038/Ng.2963 |
0.463 |
|
| 2013 |
Chemaly ER, Kang S, Zhang S, McCollum L, Chen J, Bénard L, Purushothaman KR, Hajjar RJ, Lebeche D. Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin. The Journal of Physiology. 591: 5337-55. PMID 24018949 DOI: 10.1113/jphysiol.2013.258731 |
0.496 |
|
| 2013 |
Karakikes I, Chaanine AH, Kang S, Mukete BN, Jeong D, Zhang S, Hajjar RJ, Lebeche D. Therapeutic cardiac-targeted delivery of miR-1 reverses pressure overload-induced cardiac hypertrophy and attenuates pathological remodeling. Journal of the American Heart Association. 2: e000078. PMID 23612897 DOI: 10.1161/JAHA.113.000078 |
0.523 |
|
| 2012 |
Balderman JA, Lee HY, Mahoney CE, Handy DE, White K, Annis S, Lebeche D, Hajjar RJ, Loscalzo J, Leopold JA. Bone morphogenetic protein-2 decreases microRNA-30b and microRNA-30c to promote vascular smooth muscle cell calcification. Journal of the American Heart Association. 1: e003905. PMID 23316327 DOI: 10.1161/Jaha.112.003905 |
0.392 |
|
| 2012 |
LaRocca TJ, Fabris F, Chen J, Benhayon D, Zhang S, McCollum L, Schecter AD, Cheung JY, Sobie EA, Hajjar RJ, Lebeche D. Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway. American Journal of Physiology. Heart and Circulatory Physiology. 303: H353-67. PMID 22610174 DOI: 10.1152/Ajpheart.01198.2011 |
0.602 |
|
| 2011 |
Chemaly ER, Hadri L, Zhang S, Kim M, Kohlbrenner E, Sheng J, Liang L, Chen J, K-Raman P, Hajjar RJ, Lebeche D. Long-term in vivo resistin overexpression induces myocardial dysfunction and remodeling in rats. Journal of Molecular and Cellular Cardiology. 51: 144-55. PMID 21549710 DOI: 10.1016/j.yjmcc.2011.04.006 |
0.468 |
|
| 2011 |
Kang S, Chemaly ER, Hajjar RJ, Lebeche D. Resistin promotes cardiac hypertrophy via the AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) and c-Jun N-terminal kinase/insulin receptor substrate 1 (JNK/IRS1) pathways. The Journal of Biological Chemistry. 286: 18465-73. PMID 21478152 DOI: 10.1074/jbc.M110.200022 |
0.515 |
|
| 2011 |
Dhandapany PS, Fabris F, Tonk R, Illaste A, Karakikes I, Sorourian M, Sheng J, Hajjar RJ, Tartaglia M, Sobie EA, Lebeche D, Gelb BD. Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes. Journal of Molecular and Cellular Cardiology. 51: 4-15. PMID 21440552 DOI: 10.1016/J.Yjmcc.2011.03.001 |
0.519 |
|
| 2010 |
Hadri L, Bobe R, Kawase Y, Ladage D, Ishikawa K, Atassi F, Lebeche D, Kranias EG, Leopold JA, Lompré AM, Lipskaia L, Hajjar RJ. SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells Molecular Therapy. 18: 1284-1292. PMID 20461063 DOI: 10.1038/Mt.2010.77 |
0.508 |
|
| 2010 |
Jin H, Hadri L, Palomeque J, Morel C, Karakikes I, Kaprielian R, Hajjar R, Lebeche D. KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling. Journal of Molecular and Cellular Cardiology. 48: 1169-79. PMID 20051248 DOI: 10.1016/J.Yjmcc.2009.12.019 |
0.597 |
|
| 2009 |
Karakikes I, Kim M, Hadri L, Sakata S, Sun Y, Zhang W, Chemaly ER, Hajjar RJ, Lebeche D. Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a. Plos One. 4: e6474. PMID 19649297 DOI: 10.1371/Journal.Pone.0006474 |
0.537 |
|
| 2009 |
Suckau L, Fechner H, Chemaly E, Krohn S, Hadri L, Kockskämper J, Westermann D, Bisping E, Ly H, Wang X, Kawase Y, Chen J, Liang L, Sipo I, Vetter R, ... ... Lebeche D, et al. Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy. Circulation. 119: 1241-52. PMID 19237664 DOI: 10.1161/CIRCULATIONAHA.108.783852 |
0.558 |
|
| 2008 |
Lebeche D, Davidoff AJ, Hajjar RJ. Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy. Nature Clinical Practice. Cardiovascular Medicine. 5: 715-24. PMID 18813212 DOI: 10.1038/ncpcardio1347 |
0.514 |
|
| 2008 |
Refaat M, Chemaly E, Lebeche D, Gwathmey JK, Hajjar RJ. Ventricular arrhythmias after left ventricular assist device implantation. Pacing and Clinical Electrophysiology : Pace. 31: 1246-52. PMID 18811803 DOI: 10.1111/j.1540-8159.2008.01173.x |
0.525 |
|
| 2008 |
Kim M, Oh JK, Sakata S, Liang I, Park W, Hajjar RJ, Lebeche D. Role of resistin in cardiac contractility and hypertrophy. Journal of Molecular and Cellular Cardiology. 45: 270-80. PMID 18597775 DOI: 10.1016/j.yjmcc.2008.05.006 |
0.601 |
|
| 2008 |
Misra P, Lebeche D, Ly H, Schwarzkopf M, Diaz G, Hajjar RJ, Schecter AD, Frangioni JV. Quantitation of CXCR4 expression in myocardial infarction using 99mTc-labeled SDF-1alpha. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 963-9. PMID 18483105 DOI: 10.2967/Jnumed.107.050054 |
0.428 |
|
| 2008 |
Kawase Y, Ly HQ, Prunier F, Lebeche D, Shi Y, Jin H, Hadri L, Yoneyama R, Hoshino K, Takewa Y, Sakata S, Peluso R, Zsebo K, Gwathmey JK, Tardif JC, et al. Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure. Journal of the American College of Cardiology. 51: 1112-9. PMID 18342232 DOI: 10.1016/J.Jacc.2007.12.014 |
0.564 |
|
| 2007 |
Sakata S, Liang L, Sakata N, Sakata Y, Chemaly ER, Lebeche D, Takewa Y, Chen J, Park WJ, Kawase Y, Hajjar RJ. Preservation of mechanical and energetic function after adenoviral gene transfer in normal rat hearts. Clinical and Experimental Pharmacology & Physiology. 34: 1300-6. PMID 17973872 DOI: 10.1111/j.1440-1681.2007.04742.x |
0.567 |
|
| 2007 |
Kühn B, del Monte F, Hajjar RJ, Chang YS, Lebeche D, Arab S, Keating MT. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nature Medicine. 13: 962-9. PMID 17632525 DOI: 10.1038/nm1619 |
0.545 |
|
| 2007 |
Sakata S, Lebeche D, Sakata N, Sakata Y, Chemaly ER, Liang LF, Tsuji T, Takewa Y, del Monte F, Peluso R, Zsebo K, Jeong D, Park WJ, Kawase Y, Hajjar RJ. Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins. Journal of Molecular and Cellular Cardiology. 42: 852-61. PMID 17300800 DOI: 10.1016/j.yjmcc.2007.01.003 |
0.474 |
|
| 2007 |
Sakata S, Lebeche D, Sakata N, Sakata Y, Chemaly ER, Liang LF, Takewa Y, Jeong D, Park WJ, Kawase Y, Hajjar RJ. Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2356-63. PMID 17220178 DOI: 10.1152/ajpheart.01310.2006 |
0.532 |
|
| 2007 |
Sakata S, Lebeche D, Sakata Y, Sakata N, Chemaly ER, Liang L, Nakajima-Takenaka C, Tsuji T, Konishi N, del Monte F, Hajjar RJ, Takaki M. Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1204-7. PMID 17012346 DOI: 10.1152/ajpheart.00892.2006 |
0.508 |
|
| 2006 |
Lebeche D, Kaprielian R, Hajjar R. Modulation of action potential duration on myocyte hypertrophic pathways. Journal of Molecular and Cellular Cardiology. 40: 725-35. PMID 16600293 DOI: 10.1016/J.Yjmcc.2006.01.018 |
0.531 |
|
| 2006 |
Sakata S, Lebeche D, Sakata Y, Sakata N, Chemaly ER, Liang LF, Padmanabhan P, Konishi N, Takaki M, del Monte F, Hajjar RJ. Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 987-96. PMID 16503203 DOI: 10.1016/j.ymthe.2006.01.002 |
0.538 |
|
| 2005 |
Lebeche D, Dalal R, Jang M, del Monte F, Hajjar RJ. Transgenic models of heart failure: elucidation of the molecular mechanisms of heart disease. Heart Failure Clinics. 1: 219-36. PMID 17386848 DOI: 10.1016/j.hfc.2005.03.005 |
0.529 |
|
| 2005 |
Schmidt U, Zhu X, Lebeche D, Huq F, Guerrero JL, Hajjar RJ. In vivo gene transfer of parvalbumin improves diastolic function in aged rat hearts. Cardiovascular Research. 66: 318-23. PMID 15820200 DOI: 10.1016/j.cardiores.2004.06.028 |
0.575 |
|
| 2004 |
Lebeche D, Kaprielian R, del Monte F, Tomaselli G, Gwathmey JK, Schwartz A, Hajjar RJ. In vivo cardiac gene transfer of Kv4.3 abrogates the hypertrophic response in rats after aortic stenosis. Circulation. 110: 3435-43. PMID 15557376 DOI: 10.1161/01.Cir.0000148176.33730.3F |
0.548 |
|
| 2004 |
Huq F, Lebeche D, Iyer V, Liao R, Hajjar RJ. Gene transfer of parvalbumin improves diastolic dysfunction in senescent myocytes. Circulation. 109: 2780-5. PMID 15173024 DOI: 10.1161/01.CIR.0000131764.62242.96 |
0.503 |
|
| 2004 |
del Monte F, Lebeche D, Guerrero JL, Tsuji T, Doye AA, Gwathmey JK, Hajjar RJ. Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling. Proceedings of the National Academy of Sciences of the United States of America. 101: 5622-7. PMID 15044708 DOI: 10.1073/pnas.0305778101 |
0.563 |
|
| 2003 |
Okafor CC, Perreault-Micale C, Hajjar RJ, Lebeche D, Skiroman K, Jabbour G, Doye AA, Lee MX, Laste N, Gwathmey JK. Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure Bmc Physiology [Electronic Resource]. 3: 6. PMID 12873352 DOI: 10.1186/1472-6793-3-1 |
0.53 |
|
| 2003 |
Communal C, Huq F, Lebeche D, Mestel C, Gwathmey JK, Hajjar RJ. Decreased efficiency of adenovirus-mediated gene transfer in aging cardiomyocytes. Circulation. 107: 1170-5. PMID 12615797 |
0.439 |
|
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