Lao H. Saal, Ph.D. - Publications

Affiliations: 
2007 Columbia University, New York, NY 
Area:
Molecular Biology, Genetics, Bioinformatics Biology

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 She QB, Gruvberger-Saal SK, Maurer M, Chen Y, Jumppanen M, Su T, Dendy M, Lau YK, Memeo L, Horlings HM, van de Vijver MJ, Isola J, Hibshoosh H, Rosen N, Parsons R, ... Saal LH, et al. Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer. Bmc Cancer. 16: 587. PMID 27484095 DOI: 10.1186/s12885-016-2609-2  0.6
2016 Brueffer C, Saal LH. TopHat-Recondition: a post-processor for TopHat unmapped reads. Bmc Bioinformatics. 17: 199. PMID 27142976 DOI: 10.1186/s12859-016-1058-x  0.6
2016 Lasič S, Oredsson S, Partridge SC, Saal LH, Topgaard D, Nilsson M, Bryskhe K. Apparent exchange rate for breast cancer characterization Nmr in Biomedicine. DOI: 10.1002/nbm.3504  0.6
2015 Olsson E, Winter C, George A, Chen Y, Törngren T, Bendahl PO, Borg Å, Gruvberger-Saal SK, Saal LH. Mutation Screening of 1,237 Cancer Genes across Six Model Cell Lines of Basal-Like Breast Cancer. Plos One. 10: e0144528. PMID 26670335 DOI: 10.1371/journal.pone.0144528  0.6
2015 Tang ME, Dahlgren M, Brueffer C, Tjitrowirjo T, Winter C, Chen Y, Olsson E, Wang K, Törngren T, Sjöström M, Grabau D, Bendahl PO, Rydén L, Niméus E, Saal LH, et al. Remarkable similarities of chromosomal rearrangements between primary human breast cancers and matched distant metastases as revealed by whole-genome sequencing. Oncotarget. PMID 26439695 DOI: 10.18632/oncotarget.5951  0.6
2015 Mehmeti M, Allaoui R, Bergenfelz C, Saal LH, Ethier SP, Johansson ME, Jirström K, Leandersson K. Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer. Breast Cancer Research : Bcr. 17: 130. PMID 26392082 DOI: 10.1186/s13058-015-0640-x  0.6
2015 Chen Y, van de Vijver MJ, Hibshoosh H, Parsons R, Saal LH. PTEN and NEDD4 in Human Breast Carcinoma. Pathology Oncology Research : Por. PMID 26276352 DOI: 10.1007/s12253-015-9971-2  0.6
2015 Alkner S, Tang MH, Brueffer C, Dahlgren M, Chen Y, Olsson E, Winter C, Baker S, Ehinger A, Rydén L, Saal LH, Fernö M, Gruvberger-Saal SK. Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing. Breast Cancer Research : Bcr. 17: 102. PMID 26242876 DOI: 10.1186/s13058-015-0608-x  0.6
2015 Olsson E, Winter C, George A, Chen Y, Howlin J, Tang MH, Dahlgren M, Schulz R, Grabau D, van Westen D, Fernö M, Ingvar C, Rose C, Bendahl PO, Rydén L, ... ... Saal LH, et al. Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease. Embo Molecular Medicine. PMID 25987569 DOI: 10.15252/emmm.201404913  0.6
2015 Saal LH, Vallon-Christersson J, Häkkinen J, Hegardt C, Grabau D, Winter C, Brueffer C, Tang MH, Reuterswärd C, Schulz R, Karlsson A, Ehinger A, Malina J, Manjer J, Malmberg M, et al. The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine. Genome Medicine. 7: 20. PMID 25722745 DOI: 10.1186/s13073-015-0131-9  0.6
2015 Cirenajwis H, Ekedahl H, Lauss M, Harbst K, Carneiro A, Enoksson J, Rosengren F, Werner-Hartman L, Törngren T, Kvist A, Fredlund E, Bendahl PO, Jirström K, Lundgren L, Howlin J, ... ... Saal LH, et al. Molecular stratification of metastatic melanoma using gene expression profiling - Prediction of survival outcome and benefit from molecular targeted therapy Oncotarget. 6: 12297-12309.  0.6
2014 Harbst K, Lauss M, Cirenajwis H, Winter C, Howlin J, Törngren T, Kvist A, Nodin B, Olsson E, Häkkinen J, Jirström K, Staaf J, Lundgren L, Olsson H, Ingvar C, ... ... Saal LH, et al. Molecular and genetic diversity in the metastatic process of melanoma. The Journal of Pathology. 233: 39-50. PMID 24399611 DOI: 10.1002/path.4318  0.6
2013 Pires MM, Hopkins BD, Saal LH, Parsons RE. Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells. Cancer Biology & Therapy. 14: 246-53. PMID 23291982 DOI: 10.4161/cbt.23297  0.6
2012 Holm K, Grabau D, Lövgren K, Aradottir S, Gruvberger-Saal S, Howlin J, Saal LH, Ethier SP, Bendahl PO, Stål O, Malmström P, Fernö M, Rydén L, Hegardt C, Borg Å, et al. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes. Molecular Oncology. 6: 494-506. PMID 22766277 DOI: 10.1016/j.molonc.2012.06.002  0.6
2012 Jönsson G, Staaf J, Vallon-Christersson J, Ringnér M, Gruvberger-Saal SK, Saal LH, Holm K, Hegardt C, Arason A, Fagerholm R, Persson C, Grabau D, Johnsson E, Lövgren K, Magnusson L, et al. The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer. Cancer Research. 72: 4028-36. PMID 22706203 DOI: 10.1158/0008-5472.CAN-12-0097  0.6
2011 Olsson E, Honeth G, Bendahl PO, Saal LH, Gruvberger-Saal S, Ringnér M, Vallon-Christersson J, Jönsson G, Holm K, Lövgren K, Fernö M, Grabau D, Borg A, Hegardt C. CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers. Bmc Cancer. 11: 418. PMID 21957977 DOI: 10.1186/1471-2407-11-418  0.6
2009 Fine B, Hodakoski C, Koujak S, Su T, Saal LH, Maurer M, Hopkins B, Keniry M, Sulis ML, Mense S, Hibshoosh H, Parsons R. Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. Science (New York, N.Y.). 325: 1261-5. PMID 19729658 DOI: 10.1126/science.1173569  0.6
2009 Maurer M, Su T, Saal LH, Koujak S, Hopkins BD, Barkley CR, Wu J, Nandula S, Dutta B, Xie Y, Chin YR, Kim DI, Ferris JS, Gruvberger-Saal SK, Laakso M, et al. 3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma. Cancer Research. 69: 6299-306. PMID 19602588 DOI: 10.1158/0008-5472.CAN-09-0820  0.6
2008 Honeth G, Bendahl PO, Ringnér M, Saal LH, Gruvberger-Saal SK, Lövgren K, Grabau D, Fernö M, Borg A, Hegardt C. The CD44+/CD24- phenotype is enriched in basal-like breast tumors. Breast Cancer Research : Bcr. 10: R53. PMID 18559090 DOI: 10.1186/bcr2108  0.6
2008 Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, et al. Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. Nature Genetics. 40: 102-7. PMID 18066063 DOI: 10.1038/ng.2007.39  0.6
2007 Persson O, Krogh M, Saal LH, Englund E, Liu J, Parsons R, Mandahl N, Borg A, Widegren B, Salford LG. Microarray analysis of gliomas reveals chromosomal position-associated gene expression patterns and identifies potential immunotherapy targets. Journal of Neuro-Oncology. 85: 11-24. PMID 17634744 DOI: 10.1007/s11060-007-9383-6  0.6
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