Barbara A. Seaton - Publications

Affiliations: 
Physiology and Biophysics Boston University, Boston, MA, United States 
Area:
Medical Biophysics
Website:
http://www.bumc.bu.edu/phys-biophys/people/faculty/seaton/

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Rynkiewicz MJ, Wu H, Cafarella TR, Nikolaidis NM, Head JF, Seaton BA, McCormack FX. Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop. Biochemistry. PMID 28719181 DOI: 10.1021/acs.biochem.6b01313  1
2016 Goh BC, Wu H, Rynkiewicz MJ, Schulten K, Seaton BA, McCormack FX. Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations. Biochemistry. PMID 27324153 DOI: 10.1021/acs.biochem.6b00048  1
2014 Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Roche MI, Seaton BA, Sharon J. Functional and structural characterization of Francisella tularensis O-antigen antibodies at the low end of antigen reactivity. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33: 235-45. PMID 25171003 DOI: 10.1089/mab.2014.0022  1
2014 Lu Z, Rynkiewicz MJ, Madico G, Li S, Yang CY, Perkins HM, Sompuram SR, Kodela V, Liu T, Morris T, Wang D, Roche MI, Seaton BA, Sharon J. B-cell epitopes in GroEL of Francisella tularensis. Plos One. 9: e99847. PMID 24968190 DOI: 10.1371/journal.pone.0099847  1
2014 Nikolaidis NM, White MR, Allen K, Tripathi S, Qi L, McDonald B, Taubenberger J, Seaton BA, McCormack FX, Crouch EC, Hartshorn KL. Mutations flanking the carbohydrate binding site of surfactant protein D confer antiviral activity for pandemic influenza A viruses. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L1036-44. PMID 24705721 DOI: 10.1152/ajplung.00035.2014  1
2013 Goh BC, Rynkiewicz MJ, Cafarella TR, White MR, Hartshorn KL, Allen K, Crouch EC, Calin O, Seeberger PH, Schulten K, Seaton BA. Molecular mechanisms of inhibition of influenza by surfactant protein D revealed by large-scale molecular dynamics simulation. Biochemistry. 52: 8527-38. PMID 24224757 DOI: 10.1021/bi4010683  1
2013 Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Wang Q, Costello CE, Zaia J, Seaton BA, Sharon J. The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide. Immunology. 140: 374-89. PMID 23844703 DOI: 10.1111/imm.12150  1
2012 Rynkiewicz MJ, Lu Z, Hui JH, Sharon J, Seaton BA. Structural analysis of a protective epitope of the Francisella tularensis O-polysaccharide. Biochemistry. 51: 5684-94. PMID 22747335 DOI: 10.1021/bi201711m  1
2012 van Eijk M, Rynkiewicz MJ, White MR, Hartshorn KL, Zou X, Schulten K, Luo D, Crouch EC, Cafarella TR, Head JF, Haagsman HP, Seaton BA. A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D. The Journal of Biological Chemistry. 287: 26666-77. PMID 22685299 DOI: 10.1074/jbc.M112.368571  1
2012 Yu P, Strug I, Cafarella TR, Seaton BA, Krantz A. Site-specific crosslinking of annexin proteins by 1,4-benzoquinone: a novel crosslinker for the formation of protein dimers and diverse protein conjugates. Organic & Biomolecular Chemistry. 10: 4500-4. PMID 22573340 DOI: 10.1039/c2ob25460c  1
2011 Crouch E, Nikolaidis N, McCormack FX, McDonald B, Allen K, Rynkiewicz MJ, Cafarella TM, White M, Lewnard K, Leymarie N, Zaia J, Seaton BA, Hartshorn KL. Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo. The Journal of Biological Chemistry. 286: 40681-92. PMID 21965658 DOI: 10.1074/jbc.M111.300673  1
2011 van Eijk M, Bruinsma L, Hartshorn KL, White MR, Rynkiewicz MJ, Seaton BA, Hemrika W, Romijn RA, van Balkom BW, Haagsman HP. Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses. The Journal of Biological Chemistry. 286: 20137-51. PMID 21489996 DOI: 10.1074/jbc.M111.224469  1
2011 Shang F, Rynkiewicz MJ, McCormack FX, Wu H, Cafarella TM, Head JF, Seaton BA. Crystallographic complexes of surfactant protein A and carbohydrates reveal ligand-induced conformational change. The Journal of Biological Chemistry. 286: 757-65. PMID 21047777 DOI: 10.1074/jbc.M110.175265  1
2010 Seaton BA, Crouch EC, McCormack FX, Head JF, Hartshorn KL, Mendelsohn R. Review: Structural determinants of pattern recognition by lung collectins. Innate Immunity. 16: 143-50. PMID 20423923 DOI: 10.1177/1753425910368716  1
2009 Shi X, Shao C, Zhang X, Zambonelli C, Redfield AG, Head JF, Seaton BA, Roberts MF. Modulation of Bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface. The Journal of Biological Chemistry. 284: 15607-18. PMID 19369255 DOI: 10.1074/jbc.M901601200  1
2008 Guo S, Zhang X, Seaton BA, Roberts MF. Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C. Biochemistry. 47: 4201-10. PMID 18345643 DOI: 10.1021/bi702269u  1
2008 Shao C, Novakovic VA, Head JF, Seaton BA, Gilbert GE. Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif. The Journal of Biological Chemistry. 283: 7230-41. PMID 18160406 DOI: 10.1074/jbc.M705195200  1
2007 Shao C, Shi X, Wehbi H, Zambonelli C, Head JF, Seaton BA, Roberts MF. Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C. The Journal of Biological Chemistry. 282: 9228-35. PMID 17213187 DOI: 10.1074/jbc.M610918200  1
2006 Shao C, Zhang F, Kemp MM, Linhardt RJ, Waisman DM, Head JF, Seaton BA. Crystallographic analysis of calcium-dependent heparin binding to annexin A2. The Journal of Biological Chemistry. 281: 31689-95. PMID 16882661 DOI: 10.1074/jbc.M604502200  1
2003 Head JF, Mealy TR, McCormack FX, Seaton BA. Crystal structure of trimeric carbohydrate recognition and neck domains of surfactant protein A. The Journal of Biological Chemistry. 278: 43254-60. PMID 12913002 DOI: 10.1074/jbc.M305628200  1
2003 Stieglitz KA, Seaton BA, Head JF, Stec B, Roberts MF. Unexpected similarity in regulation between an archaeal inositol monophosphatase/fructose bisphosphatase and chloroplast fructose bisphosphatase. Protein Science : a Publication of the Protein Society. 12: 760-7. PMID 12649434 DOI: 10.1110/ps.0236003  1
2003 Mo Y, Campos B, Mealy TR, Commodore L, Head JF, Dedman JR, Seaton BA. Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces. The Journal of Biological Chemistry. 278: 2437-43. PMID 12401794 DOI: 10.1074/jbc.M210286200  1
2002 Stieglitz KA, Johnson KA, Yang H, Roberts MF, Seaton BA, Head JF, Stec B. Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop. The Journal of Biological Chemistry. 277: 22863-74. PMID 11940584 DOI: 10.1074/jbc.M201042200  1
2001 Stieglitz KA, Seaton BA, Roberts MF. Binding of proteolytically processed phospholipase D from Streptomyces chromofuscus to phosphatidylcholine membranes facilitates vesicle aggregation and fusion. Biochemistry. 40: 13954-63. PMID 11705386 DOI: 10.1021/bi011338o  1
2001 Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF. The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution. Nature Structural Biology. 8: 710-4. PMID 11473263 DOI: 10.1038/90429  1
2001 Capila I, Hernáiz MJ, Mo YD, Mealy TR, Campos B, Dedman JR, Linhardt RJ, Seaton BA. Annexin V--heparin oligosaccharide complex suggests heparan sulfate--mediated assembly on cell surfaces. Structure (London, England : 1993). 9: 57-64. PMID 11342135 DOI: 10.1016/S0969-2126(00)00549-9  1
2001 Kaetzel MA, Mo YD, Mealy TR, Campos B, Bergsma-Schutter W, Brisson A, Dedman JR, Seaton BA. Phosphorylation mutants elucidate the mechanism of annexin IV-mediated membrane aggregation Biochemistry. 40: 4192-4199. PMID 11300800 DOI: 10.1021/bi002507s  1
1999 Campos B, Wang S, Retzinger GS, Kaetzel MA, Seaton BA, Karin NJ, Johnson JD, Dedman JR. Mutation of highly conserved arginine residues disrupts the structure and function of Annexin V Archives of Medical Research. 30: 360-367. PMID 10596454 DOI: 10.1016/S0188-0128(99)00040-8  1
1999 Capila I, VanderNoot VA, Mealy TR, Seaton BA, Linhardt RJ. Interaction of heparin with annexin V. Febs Letters. 446: 327-30. PMID 10100868 DOI: 10.1016/S0014-5793(99)00245-8  1
1999 Wu F, Flach CR, Seaton BA, Mealy TR, Mendelsohn R. Stability of annexin V in ternary complexes with CA2+ and anionic phospholipids: IR studies of monolayer and bulk phases Biochemistry. 38: 792-799. PMID 9888820 DOI: 10.1021/bi9819677  1
1998 Seaton BA, Dedman JR. Annexins Biometals. 11: 399-404. PMID 10191502 DOI: 10.1023/A:1009205925714  1
1998 Wu F, Gericke A, Flach CR, Mealy TR, Seaton BA, Mendelsohn R. Domain structure and molecular conformation in annexin V/1,2- dimyristoyl-sn-glycero-3-phosphate/Ca2+ aqueous monolayers: A Brewster angle microscopy/infrared reflection-absorption spectroscopy study Biophysical Journal. 74: 3273-3281. PMID 9635781  1
1998 Campos B, Mo YD, Mealy TR, Li CW, Swairjo MA, Balch C, Head JF, Retzinger G, Dedman JR, Seaton BA. Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components Biochemistry. 37: 8004-8010. PMID 9609693 DOI: 10.1021/bi973142n  1
1997 Jin L, Seaton BA, Head JF. Crystal structure at 2.8 Å resolution of anabolic ornithine transcarbamylase from Escherichia coli Nature Structural Biology. 4: 622-625. PMID 9253409 DOI: 10.1038/nsb0897-622  1
1997 Rynkiewicz MJ, Seaton BA. Protein Crystallography in Medicine Advances in Molecular and Cell Biology. 22: 1-50. DOI: 10.1016/S1569-2558(08)60105-8  1
1996 Rynkiewicz MJ, Seaton BA. Chemical rescue by guanidine derivatives of an arginine-substituted site-directed mutant of Escherichia coli ornithine transcarbamylase Biochemistry. 35: 16174-16179. PMID 8973189 DOI: 10.1021/bi961311i  1
1995 Swairjo MA, Concha NO, Kaetzel MA, Dedman JR, Seaton BA. Ca2+-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V Nature Structural Biology. 2: 968-974. PMID 7583670 DOI: 10.1038/nsb1195-968  1
1994 Swairjo MA, Seaton BA, Roberts MF. Effect of vesicle composition and curvature on the dissociation of phosphatidic acid in small unilamellar vesicles--a 31P-NMR study. Biochimica Et Biophysica Acta. 1191: 354-61. PMID 8172921 DOI: 10.1016/0005-2736(94)90186-4  1
1994 Swairjo MA, Roberts MF, Campos MB, Dedman JR, Seaton BA. Annexin V binding to the outer leaflet of small unilamellar vesicles leads to altered inner-leaflet properties: 31P- and 1H-NMR studies. Biochemistry. 33: 10944-50. PMID 8086411  1
1994 Seaton BA, Head JF. Shaking hands with yourself Nature Structural Biology. 1: 350-351. PMID 7664043  1
1994 Swairjo MA, Seaton BA. Annexin structure and membrane interactions: A molecular perspective Annual Review of Biophysics and Biomolecular Structure. 23: 193-213. PMID 7522665  1
1993 Concha NO, Head JF, Kaetzel MA, Dedman JR, Seaton BA. Rat annexin V crystal structure: Ca2+-induced conformational changes Science. 261: 1321-1324. PMID 8362244  1
1992 Concha NO, Head JF, Kaetzel MA, Dedman JR, Seaton BA. Annexin V forms calcium-dependent trimeric units on phospholipid vesicles Febs Letters. 314: 159-162. PMID 1459245 DOI: 10.1016/0014-5793(92)80964-I  1
1991 Davenport RC, Bash PA, Seaton BA, Karplus M, Petsko GA, Ringe D. Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analogue of the intermediate on the reaction pathway. Biochemistry. 30: 5821-6. PMID 2043623  1
1990 Seaton BA, Head JF, Kaetzel MA, Dedman JR. Purification, crystallization, and preliminary X-ray diffraction analysis of rat kidney annexin V, a calcium-dependent phospholipid-binding protein Journal of Biological Chemistry. 265: 4567-4569. PMID 2307675  1
1990 Ke HM, Thorpe CM, Seaton Ba, Lipscomb WN, Marcus F. Structure refinement of fructose-1,6-bisphosphatase and its fructose 2,6-bisphosphate complex at 2.8 A resolution. Journal of Molecular Biology. 212: 513-39. PMID 2157849 DOI: 10.1016/0022-2836(90)90329-K  1
1989 Kataoka M, Head JF, Seaton BA, Engelman DM. Melittin binding causes a large calcium-dependent conformational change in calmodulin Proceedings of the National Academy of Sciences of the United States of America. 86: 6944-6948. PMID 2780551  1
1989 Kuo LC, Seaton BA. X-ray diffraction analysis on single crystals of recombinant Escherichia coli ornithine transcarbamoylase Journal of Biological Chemistry. 264: 16246-16248. PMID 2674127  1
1989 Ke H, Thorpe CM, Seaton BA, Marcus F, Lipscomb WN. Molecular structure of fructose-1,6-bisphosphatase at 2.8-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 86: 1475-9. PMID 2537975  1
1986 Seaton BA. Raman spectroscopic studies of beta-turn-containing cyclic peptides Spectrochimica Acta Part a: Molecular Spectroscopy. 42: 227-232. DOI: 10.1016/0584-8539(86)80184-2  1
1985 Seaton BA, Head JF, Engelman DM, Richards FM. Calcium-induced increase in the radius of gyration and maximum dimension of calmodulin measured by small-angle X-ray scattering Biochemistry. 24: 6740-6743. PMID 4074724  1
1985 Ringe D, Seaton BA, Gelb MH, Abeles RH. Inactivation of chymotrypsin by 5-benzyl-6-chloro-2-pyrone: 13C NMR and X-ray diffraction analyses of the inactivator-enzyme complex. Biochemistry. 24: 64-8. PMID 3994973  1
1985 Lord RC, Petsko GA, Seaton BA, Goodfriend L. Laser Raman spectroscopy of biomolecules: Structural studies of ragweed allergen Ra5 Spectrochimica Acta Part a: Molecular Spectroscopy. 41: 199-203. DOI: 10.1016/0584-8539(85)80097-0  1
1984 Seaton BA, Campbell RL, Petsko GA, Rose DR, Edelstein I, Marcus F. Preliminary X-ray crystallographic studies of pig kidney fructose-1,6-bisphosphatase. The Journal of Biological Chemistry. 259: 8915-6. PMID 6086617  1
1983 Rose DR, Seaton BA, Petsko GA, Novotný J, Margolies MN, Locke E, Haber E. Crystallization of the Fab fragment of a monoclonal anti-digoxin antibody and its complex with digoxin. Journal of Molecular Biology. 165: 203-6. PMID 6842605 DOI: 10.1016/S0022-2836(83)80252-6  1
1983 Seaton BA, Head JF, Lord RC, Petsko GA. Studies of calmodulin structure: laser raman spectroscopy of biomolecules. Biochemistry. 22: 973-8. PMID 6301532  1
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