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De-Ming Chau, Ph.D. - Publications

Affiliations: 
2011 Weill Cornell Medical College, New York, NY, United States 
Area:
Biochemistry, Pharmacology, Neuroscience Biology, Oncology
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yusof HH, Lee HC, Seth EA, Wu X, Hewitt CA, Scott HS, Cheah PS, Li YM, Chau DM, Ling KH. Expression Profiling of Notch Signalling Pathway and Gamma-Secretase Activity in the Brain of Ts1Cje Mouse Model of Down Syndrome. Journal of Molecular Neuroscience : Mn. PMID 30758748 DOI: 10.1007/s12031-019-01275-2  0.496
2015 Gertsik N, Chau DM, Li YM. γ-Secretase Inhibitors and Modulators Induce Distinct Conformational Changes in the Active Sites of γ-Secretase and Signal Peptide Peptidase. Acs Chemical Biology. 10: 1925-31. PMID 26030233 DOI: 10.1021/acschembio.5b00321  0.621
2013 Chau DM, Shum D, Radu C, Bhinder B, Gin D, Gilchrist ML, Djaballah H, Li YM. A novel high throughput 1536-well notch1 γsecretase AlphaLISA assay Combinatorial Chemistry and High Throughput Screening. 16: 415-424. PMID 23448293 DOI: 10.2174/1386207311316060001  0.573
2012 Chau DM, Crump CJ, Villa JC, Scheinberg DA, Li YM. Familial Alzheimer disease presenilin-1 mutations alter the active site conformation of γ-secretase. The Journal of Biological Chemistry. 287: 17288-96. PMID 22461631 DOI: 10.1074/Jbc.M111.300483  0.576
2012 Crump CJ, am Ende CW, Ballard TE, Pozdnyakov N, Pettersson M, Chau DM, Bales KR, Li YM, Johnson DS. Development of clickable active site-directed photoaffinity probes for γ-secretase. Bioorganic & Medicinal Chemistry Letters. 22: 2997-3000. PMID 22418280 DOI: 10.1016/J.Bmcl.2012.02.027  0.557
2011 Crump CJ, Fish BA, Castro SV, Chau DM, Gertsik N, Ahn K, Stiff C, Pozdnyakov N, Bales KR, Johnson DS, Li YM. Piperidine acetic acid based γ-secretase modulators directly bind to Presenilin-1. Acs Chemical Neuroscience. 2: 705-710. PMID 22229075 DOI: 10.1021/Cn200098P  0.593
2009 Shelton CC, Zhu L, Chau D, Yang L, Wang R, Djaballah H, Zheng H, Li YM. Modulation of gamma-secretase specificity using small molecule allosteric inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 106: 20228-33. PMID 19906985 DOI: 10.1073/Pnas.0910757106  0.62
2008 Gómez-Nuñez M, Haro KJ, Dao T, Chau D, Won A, Escobar-Alvarez S, Zakhaleva V, Korontsvit T, Gin DY, Scheinberg DA. Non-natural and photo-reactive amino acids as biochemical probes of immune function. Plos One. 3: e3938. PMID 19079589 DOI: 10.1371/Journal.Pone.0003938  0.333
2007 Haro KJ, Gomez-Nunez M, Dao T, Chau D, Won A, Escobar-Alvarez S, Zakhaleva V, Korontsvit T, Gin D, Scheinberg DA. Photo-Reactive and Non-Natural Amino Acid Epitopes of Human WT1 Enhance Immunogenicity and Allow Kinetic Study of Antigen Processing. Blood. 110: 2311-2311. DOI: 10.1182/Blood.V110.11.2311.2311  0.33
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