Joshua Mendell - Publications

Affiliations: 
Human Genetics Johns Hopkins University, Baltimore, MD 
Area:
Genetics, Molecular Biology

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jones BT, Han J, Zhang H, Hammer RE, Evers BM, Rakheja D, Acharya A, Mendell JT. Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Genes & Development. PMID 37553261 DOI: 10.1101/gad.350906.123  0.578
2023 Jones BT, Han J, Zhang H, Hammer RE, Evers BM, Rakheja D, Acharya A, Mendell JT. Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Biorxiv : the Preprint Server For Biology. PMID 37425885 DOI: 10.1101/2023.06.26.546601  0.578
2022 Han J, Mendell JT. MicroRNA turnover: a tale of tailing, trimming, and targets. Trends in Biochemical Sciences. PMID 35811249 DOI: 10.1016/j.tibs.2022.06.005  0.517
2020 Han J, LaVigne CA, Jones BT, Zhang H, Gillett F, Mendell JT. A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming. Science (New York, N.Y.). PMID 33184234 DOI: 10.1126/science.abc9546  0.523
2019 Acharya A, Berry DC, Zhang H, Jiang Y, Jones BT, Hammer RE, Graff JM, Mendell JT. miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting . Genes & Development. PMID 31488578 DOI: 10.1101/Gad.328955.119  0.429
2019 Du Q, Hoover AR, Dozmorov I, Raj P, Khan S, Molina E, Chang TC, de la Morena MT, Cleaver OB, Mendell JT, van Oers NSC. MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary. Developmental Cell. PMID 30982661 DOI: 10.1016/J.Devcel.2019.03.012  0.521
2018 Chang TC, Mendell JT. High-Throughput Characterization of Primary microRNA Transcripts. Methods in Molecular Biology (Clifton, N.J.). 1823: 1-9. PMID 29959669 DOI: 10.1007/978-1-4939-8624-8_1  0.506
2017 Heller KN, Mendell JT, Mendell JR, Rodino-Klapac LR. MicroRNA-29 overexpression by adeno-associated virus suppresses fibrosis and restores muscle function in combination with micro-dystrophin. Jci Insight. 2. PMID 28469083 DOI: 10.1172/Jci.Insight.93309  0.347
2017 Golden RJ, Chen B, Li T, Braun J, Manjunath H, Chen X, Wu J, Schmid V, Chang TC, Kopp F, Ramirez-Martinez A, Tagliabracci VS, Chen ZJ, Xie Y, Mendell JT. An Argonaute phosphorylation cycle promotes microRNA-mediated silencing. Nature. PMID 28114302 DOI: 10.1038/Nature21025  0.504
2016 Kent OA, Mendell JT, Rottapel R. Transcriptional Regulation of miR-31 by Oncogenic KRAS Mediates Metastatic Phenotypes by Repressing RASA1. Molecular Cancer Research : McR. 14: 267-77. PMID 26747707 DOI: 10.1158/1541-7786.Mcr-15-0456  0.529
2015 Chang TC, Pertea M, Lee S, Salzberg SL, Mendell JT. Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms. Genome Research. 25: 1401-9. PMID 26290535 DOI: 10.1101/Gr.193607.115  0.513
2015 Knabel MK, Ramachandran K, Karhadkar S, Hwang HW, Creamer TJ, Chivukula RR, Sheikh F, Clark KR, Torbenson M, Montgomery RA, Cameron AM, Mendell JT, Warren DS. Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice. Plos One. 10: e0124411. PMID 25923107 DOI: 10.1371/Journal.Pone.0124411  0.793
2015 Huang TC, Renuse S, Pinto S, Kumar P, Yang Y, Chaerkady R, Godsey B, Mendell JT, Halushka MK, Civin CI, Marchionni L, Pandey A. Identification of miR-145 targets through an integrated omics analysis. Molecular Biosystems. 11: 197-207. PMID 25354783 DOI: 10.1039/C4Mb00585F  0.591
2014 Shi G, Mendell JT. Seeing through the miRage of tissue complexity. Cell Cycle (Georgetown, Tex.). 13: 2988-9. PMID 25486556 DOI: 10.4161/15384101.2014.962852  0.542
2014 Zeitels LR, Acharya A, Shi G, Chivukula D, Chivukula RR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Richardson JA, Mendell JT. Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis. Genes & Development. 28: 2585-90. PMID 25395662 DOI: 10.1101/Gad.250951.114  0.751
2014 Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nature Communications. 2: 4802. PMID 25190313 DOI: 10.1038/Ncomms5802  0.464
2014 Krzeszinski JY, Wei W, Huynh H, Jin Z, Wang X, Chang TC, Xie XJ, He L, Mangala LS, Lopez-Berestein G, Sood AK, Mendell JT, Wan Y. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2. Nature. 512: 431-5. PMID 25043055 DOI: 10.1038/Nature13375  0.324
2014 Chivukula RR, Shi G, Acharya A, Mills EW, Zeitels LR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Maitra A, Mendell JT. An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell. 157: 1104-16. PMID 24855947 DOI: 10.1016/J.Cell.2014.03.055  0.801
2013 Zeitels LR, Mendell JT. When 19 is greater than 92. Elife. 2: e01514. PMID 24137549 DOI: 10.7554/eLife.01514  0.417
2012 Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, ... ... Mendell JT, et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. The Journal of Clinical Investigation. 122: 2871-83. PMID 22820288 DOI: 10.1172/Jci63539  0.768
2012 Ribas J, Ni X, Castanares M, Liu MM, Esopi D, Yegnasubramanian S, Rodriguez R, Mendell JT, Lupold SE. A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts. Nucleic Acids Research. 40: 6821-33. PMID 22505577 DOI: 10.1093/Nar/Gks308  0.486
2012 Mendell JT, Olson EN. MicroRNAs in stress signaling and human disease. Cell. 148: 1172-87. PMID 22424228 DOI: 10.1016/J.Cell.2012.02.005  0.483
2011 Chaulk SG, Thede GL, Kent OA, Xu Z, Gesner EM, Veldhoen RA, Khanna SK, Goping IS, MacMillan AM, Mendell JT, Young HS, Fahlman RP, Glover JN. Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis. Rna Biology. 8: 1105-14. PMID 21955497 DOI: 10.4161/Rna.8.6.17410  0.585
2011 Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT, Maitra A. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Molecular Cancer Therapeutics. 10: 1470-80. PMID 21622730 DOI: 10.1158/1535-7163.Mct-11-0152  0.806
2011 Lee YN, Brandal S, Noel P, Wentzel E, Mendell JT, McDevitt MA, Kapur R, Carter M, Metcalfe DD, Takemoto CM. KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. Blood. 117: 3629-40. PMID 21273305 DOI: 10.1182/blood-2010-07-293548  0.549
2010 Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD, Maitra A, Mendell JT. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes & Development. 24: 2754-9. PMID 21159816 DOI: 10.1101/Gad.1950610  0.773
2010 Persat A, Chivukula RR, Mendell JT, Santiago JG. Quantification of global microRNA abundance by selective isotachophoresis. Analytical Chemistry. 82: 9631-5. PMID 21062022 DOI: 10.1021/Ac102496M  0.769
2010 Bui TV, Mendell JT. Myc: Maestro of MicroRNAs. Genes & Cancer. 1: 568-575. PMID 20882107 DOI: 10.1177/1947601910377491  0.5
2010 Yang Y, Chaerkady R, Kandasamy K, Huang TC, Selvan LD, Dwivedi SB, Kent OA, Mendell JT, Pandey A. Identifying targets of miR-143 using a SILAC-based proteomic approach. Molecular Biosystems. 6: 1873-82. PMID 20544124 DOI: 10.1039/C004401F  0.59
2010 Yamakuchi M, Lotterman CD, Bao C, Hruban RH, Karim B, Mendell JT, Huso D, Lowenstein CJ. P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6334-9. PMID 20308559 DOI: 10.1073/Pnas.0911082107  0.409
2009 Kent OA, Mullendore M, Wentzel EA, López-Romero P, Tan AC, Alvarez H, West K, Ochs MF, Hidalgo M, Arking DE, Maitra A, Mendell JT. A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. Cancer Biology & Therapy. 8: 2013-24. PMID 20037478 DOI: 10.4161/Cbt.8.21.9685  0.614
2009 Ribas J, Ni X, Haffner M, Wentzel EA, Salmasi AH, Chowdhury WH, Kudrolli TA, Yegnasubramanian S, Luo J, Rodriguez R, Mendell JT, Lupold SE. miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth. Cancer Research. 69: 7165-9. PMID 19738047 DOI: 10.1158/0008-5472.Can-09-1448  0.498
2009 Mendell JT. Tumors line up for a letdown. Nature Genetics. 41: 768-9. PMID 19557079 DOI: 10.1038/ng0709-768  0.529
2009 Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell. 137: 1005-17. PMID 19524505 DOI: 10.1016/J.Cell.2009.04.021  0.799
2009 Chivukula RR, Mendell JT. Abate and switch: miR-145 in stem cell differentiation. Cell. 137: 606-8. PMID 19450510 DOI: 10.1016/J.Cell.2009.04.059  0.73
2009 Lee KH, Lotterman C, Karikari C, Omura N, Feldmann G, Habbe N, Goggins MG, Mendell JT, Maitra A. Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 9: 293-301. PMID 19407485 DOI: 10.1159/000186051  0.556
2009 Hwang HW, Wentzel EA, Mendell JT. Cell-cell contact globally activates microRNA biogenesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 7016-21. PMID 19359480 DOI: 10.1073/pnas.0811523106  0.802
2009 Yang Y, Chaerkady R, Beer MA, Mendell JT, Pandey A. Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach. Proteomics. 9: 1374-84. PMID 19253296 DOI: 10.1002/Pmic.200800551  0.587
2009 Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV. C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism Nature. 458: 762-765. PMID 19219026 DOI: 10.1038/Nature07823  0.383
2009 Habbe N, Koorstra JB, Mendell JT, Offerhaus GJ, Ryu JK, Feldmann G, Mullendore ME, Goggins MG, Hong SM, Maitra A. MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. Cancer Biology & Therapy. 8: 340-6. PMID 19106647 DOI: 10.4161/cbt.8.4.7338  0.463
2008 Yu X, Lin J, Zack DJ, Mendell JT, Qian J. Analysis of regulatory network topology reveals functionally distinct classes of microRNAs. Nucleic Acids Research. 36: 6494-503. PMID 18927108 DOI: 10.1093/Nar/Gkn712  0.498
2008 Chivukula RR, Mendell JT. Circular reasoning: microRNAs and cell-cycle control. Trends in Biochemical Sciences. 33: 474-81. PMID 18774719 DOI: 10.1016/J.Tibs.2008.06.008  0.783
2008 Lotterman CD, Kent OA, Mendell JT. Functional integration of microRNAs into oncogenic and tumor suppressor pathways. Cell Cycle (Georgetown, Tex.). 7: 2493-9. PMID 18719378 DOI: 10.4161/cc.7.16.6452  0.526
2008 Chung EY, Dews M, Cozma D, Yu D, Wentzel EA, Chang TC, Schelter JM, Cleary MA, Mendell JT, Thomas-Tikhonenko A. c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster. Cancer Biology & Therapy. 7: 1758-64. PMID 18708755 DOI: 10.4161/Cbt.7.11.6722  0.687
2008 Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell. 133: 217-22. PMID 18423194 DOI: 10.1016/j.cell.2008.04.001  0.575
2008 Harris TA, Yamakuchi M, Ferlito M, Mendell JT, Lowenstein CJ. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proceedings of the National Academy of Sciences of the United States of America. 105: 1516-21. PMID 18227515 DOI: 10.1073/Pnas.0707493105  0.331
2008 Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, West KM, Dang CV, Thomas-Tikhonenko A, Mendell JT. Widespread microRNA repression by Myc contributes to tumorigenesis Nature Genetics. 40: 43-50. PMID 18066065 DOI: 10.1038/Ng.2007.30  0.755
2007 Bruchova H, Yoon D, Agarwal AM, Mendell J, Prchal JT. Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis. Experimental Hematology. 35: 1657-67. PMID 17976518 DOI: 10.1016/J.Exphem.2007.08.021  0.527
2007 Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Molecular Cell. 26: 745-52. PMID 17540599 DOI: 10.1016/J.Molcel.2007.05.010  0.548
2007 Chang TC, Mendell JT. microRNAs in vertebrate physiology and human disease. Annual Review of Genomics and Human Genetics. 8: 215-39. PMID 17506656 DOI: 10.1146/annurev.genom.8.080706.092351  0.508
2007 Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. British Journal of Cancer. 96: R40-4. PMID 17393584  0.808
2007 Hwang HW, Wentzel EA, Mendell JT. A hexanucleotide element directs microRNA nuclear import. Science (New York, N.Y.). 315: 97-100. PMID 17204650 DOI: 10.1126/science.1136235  0.814
2007 Chung EY, Cozma D, Yu D, Dews M, Wentzel EA, Chang T, Mendell JT, Thomas-Tikhonenko A. Pax5 Activates Oncogenic Transcription Factors of the Ets Family by Repressing the mir-15a/16-1 microRNA Cluster. Blood. 110: 346-346. DOI: 10.1182/Blood.V110.11.346.346  0.694
2006 Kent OA, Mendell JT. A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene. 25: 6188-96. PMID 17028598 DOI: 10.1038/sj.onc.1209913  0.51
2006 Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, Furth EE, Lee WM, Enders GH, Mendell JT, Thomas-Tikhonenko A. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nature Genetics. 38: 1060-5. PMID 16878133 DOI: 10.1038/Ng1855  0.661
2006 Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT, Jiang J, Schmittgen TD, Patel T. Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology. 130: 2113-29. PMID 16762633 DOI: 10.1053/j.gastro.2006.02.057  0.441
2006 Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. British Journal of Cancer. 94: 776-80. PMID 16495913 DOI: 10.1038/sj.bjc.6603023  0.808
2006 Jones KA, Phillips JD, Mendell JT, Glenn MG, Yu MK. Upregulation of SOCS-1 and Downregulation of miR-214 Correlate with Disease Course in Chronic Lymphocytic Leukemia. Blood. 108: 4313-4313. DOI: 10.1182/blood.v108.11.4313.4313  0.602
2006 Bruchova H, Gaikwad AS, Mendell J, Prchal JT. Dysregulated Expression of miRNAs in Polycythemia Vera Erythroid Progenitors. Blood. 108: 3613-3613. DOI: 10.1182/Blood.V108.11.3613.3613  0.653
2006 Yu MK, Mendell JT, Glenn MG, Chen Z, Jones KA, Phillips JD. DNA Methylation Inhibitors Upregulate MiRNA Expression in Patients with Chronic Lymphocytic Leukemia. Blood. 108: 2257-2257. DOI: 10.1182/blood.v108.11.2257.2257  0.427
2005 Mendell JT. MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle (Georgetown, Tex.). 4: 1179-84. PMID 16096373 DOI: 10.4161/cc.4.9.2032  0.593
2005 O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature. 435: 839-43. PMID 15944709 DOI: 10.1038/Nature03677  0.557
2004 Mendell JT, Sharifi NA, Meyers JL, Martinez-Murillo F, Dietz HC. Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise. Nature Genetics. 36: 1073-8. PMID 15448691 DOI: 10.1038/Ng1429  0.51
2002 Mendell JT, ap Rhys CM, Dietz HC. Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts. Science (New York, N.Y.). 298: 419-22. PMID 12228722 DOI: 10.1126/Science.1074428  0.488
2002 Mendell JT, Dietz HC. When the message goes awry: disease-producing mutations that influence mRNA content and performance. Cell. 107: 411-4. PMID 11719181 DOI: 10.1016/S0092-8674(01)00583-9  0.436
2001 Medghalchi SM, Frischmeyer PA, Mendell JT, Kelly AG, Lawler AM, Dietz HC. Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. Human Molecular Genetics. 10: 99-105. PMID 11152657 DOI: 10.1093/Hmg/10.2.99  0.508
2000 Mendell JT, Medghalchi SM, Lake RG, Noensie EN, Dietz HC. Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes. Molecular and Cellular Biology. 20: 8944-57. PMID 11073994 DOI: 10.1128/Mcb.20.23.8944-8957.2000  0.699
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