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Xiaoyong Yang, Ph.D. - Publications

Affiliations: 
2001 University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Cell Biology
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57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ong Q, Lim LTR, Goh C, Liao Y, Chan SE, Lim CJY, Kam V, Yap J, Tseng T, Desrouleaux R, Wang LC, Ler SG, Lim SL, Kim SY, Sobota RM, ... ... Yang X, et al. Spatiotemporal control of subcellular O-GlcNAc signaling using Opto-OGT. Nature Chemical Biology. PMID 39543398 DOI: 10.1038/s41589-024-01770-7  0.483
2024 Zhang L, Deng T, Pan S, Zhang M, Zhang Y, Yang C, Yang X, Tian G, Mi J. DeepO-GlcNAc: a web server for prediction of protein O-GlcNAcylation sites using deep learning combined with attention mechanism. Frontiers in Cell and Developmental Biology. 12: 1456728. PMID 39450274 DOI: 10.3389/fcell.2024.1456728  0.398
2022 Wang Q, Zhang B, Stutz B, Liu ZW, Horvath TL, Yang X. Ventromedial hypothalamic OGT drives adipose tissue lipolysis and curbs obesity. Science Advances. 8: eabn8092. PMID 36044565 DOI: 10.1126/sciadv.abn8092  0.309
2022 Wu J, Liu J, Lapenta K, Desrouleaux R, Li MD, Yang X. Regulation of the urea cycle by CPS1 O-GlcNAcylation in response to dietary restriction and aging. Journal of Molecular Cell Biology. PMID 35285892 DOI: 10.1093/jmcb/mjac016  0.487
2021 Mohan R, Jo S, Da Sol Chung E, Oribamise E, Lockridge A, Abrahante-Lloréns JE, Ruan HB, Yang XY, Alejandro EU. Pancreatic β-Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Metabolic Stressors in Female Mice. Cells. 10. PMID 34685781 DOI: 10.3390/cells10102801  0.346
2021 Li R, Ong Q, Wong CC, Chu ES, Sung JJ, Yang X, Yu J. O-GlcNAcylation inhibits hepatic stellate cell activation. Journal of Gastroenterology and Hepatology. PMID 34547820 DOI: 10.1111/jgh.15690  0.46
2020 Zhao M, Ren K, Xiong X, Cheng M, Zhang Z, Huang Z, Han X, Yang X, Alejandro EU, Ruan HB. Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells. Cell Reports. 32: 108013. PMID 32783937 DOI: 10.1016/J.Celrep.2020.108013  0.482
2020 Yang Y, Li X, Luan HH, Zhang B, Zhang K, Nam JH, Li Z, Fu M, Munk A, Zhang D, Wang S, Liu Y, Albuquerque JP, Ong Q, Li R, ... ... Yang X, et al. OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance. Proceedings of the National Academy of Sciences of the United States of America. PMID 32601203 DOI: 10.1073/Pnas.1916121117  0.371
2020 Da Li, Cao T, Sun X, Jin S, Di Xie, Huang X, Yang X, Carmichael GG, Taylor HS, Diano S, Huang Y. Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform. Nature Communications. 11: 342. PMID 31953394 DOI: 10.1038/S41467-019-14185-Z  0.332
2020 Yang Y, Fu M, Li MD, Zhang K, Zhang B, Wang S, Liu Y, Ni W, Ong Q, Mi J, Yang X. O-GlcNAc transferase inhibits visceral fat lipolysis and promotes diet-induced obesity. Nature Communications. 11: 181. PMID 31924761 DOI: 10.1038/S41467-019-13914-8  0.503
2020 Wang Q, Zhang B, Yang Y, Mi J, Tian G, Ong Q, Yang X. 216-OR: O-GlcNAc Transferase in the Ventromedial Hypothalamus Regulates Lipid Metabolism through Fat Depot–Specific Sympathetic Innervation Diabetes. 69. DOI: 10.2337/Db20-216-Or  0.47
2019 Zhang B, Li MD, Yin R, Liu Y, Yang Y, Mitchell-Richards KA, Nam JH, Li R, Wang L, Iwakiri Y, Chung D, Robert ME, Ehrlich BE, Bennett AM, Yu J, ... ... Yang X, et al. O-GlcNAc transferase suppresses necroptosis and liver fibrosis. Jci Insight. 4. PMID 31672932 DOI: 10.1172/Jci.Insight.127709  0.393
2019 Singh JP, Qian K, Lee JS, Zhou J, Han X, Zhang B, Ong Q, Ni W, Jiang M, Ruan HB, Li MD, Zhang K, Ding Z, Lee P, Singh K, ... ... Yang X, et al. O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth. Oncogene. PMID 31501520 DOI: 10.1038/S41388-019-0975-3  0.526
2019 Jiang M, Xu B, Li X, Shang Y, Chu Y, Wang W, Chen D, Wu N, Hu S, Zhang S, Li M, Wu K, Yang X, Liang J, Nie Y, et al. Correction: O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit. Oncogene. PMID 31160652 DOI: 10.1038/s41388-019-0834-2  0.318
2019 Li X, Gong W, Wang H, Li T, Attri KS, Lewis RE, Kalil AC, Bhinderwala F, Powers R, Yin G, Herring LE, Asara JM, Lei YL, Yang X, Rodriguez DA, et al. O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3. Immunity. 50: 1115. PMID 30995496 DOI: 10.1016/J.Immuni.2019.03.008  0.447
2019 Li X, Gong W, Wang H, Li T, Attri KS, Lewis RE, Kalil AC, Bhinderwala F, Powers R, Yin G, Herring LE, Asara JM, Lei YL, Yang X, Rodriguez DA, et al. O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3. Immunity. PMID 30770249 DOI: 10.1016/J.Immuni.2019.01.007  0.526
2019 Li R, Ong Q, Wong CC, Sung JJ, Yang X, Y J. 241 – Regulation of Hepatic Stellate Cell Activation by O-Glcnacylation Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)39934-2  0.505
2018 Li MD, Vera NB, Yang Y, Zhang B, Ni W, Ziso-Qejvanaj E, Ding S, Zhang K, Yin R, Wang S, Zhou X, Fang EX, Xu T, Erion DM, Yang X. Adipocyte OGT governs diet-induced hyperphagia and obesity. Nature Communications. 9: 5103. PMID 30504766 DOI: 10.1038/S41467-018-07461-X  0.461
2018 Ong Q, Han W, Yang X. O-GlcNAc as an Integrator of Signaling Pathways. Frontiers in Endocrinology. 9: 599. PMID 30464755 DOI: 10.3389/Fendo.2018.00599  0.568
2018 Yu F, Guo S, Li T, Ran J, Zhao W, Li D, Liu M, Yan X, Yang X, Zhu X, Zhou J. Ciliary defects caused by dysregulation of O-GlcNAc modification are associated with diabetic complications. Cell Research. PMID 30429527 DOI: 10.1038/S41422-018-0114-7  0.399
2018 Jiang M, Xu B, Li X, Shang Y, Chu Y, Wang W, Chen D, Wu N, Hu S, Zhang S, Li M, Wu K, Yang X, Liang J, Nie Y, et al. O-GlcNAcylation promotes colorectal cancer metastasis via the miR-101-O-GlcNAc/EZH2 regulatory feedback circuit. Oncogene. PMID 30093632 DOI: 10.1038/S41388-018-0435-5  0.47
2018 Qian K, Wang S, Fu M, Zhou J, Singh JP, Li MD, Yang Y, Zhang K, Wu J, Nie Y, Ruan HB, Yang X. Transcriptional regulation of -GlcNAc homeostasis is disrupted in pancreatic cancer. The Journal of Biological Chemistry. PMID 30037904 DOI: 10.1074/Jbc.Ra118.004709  0.478
2018 Shi H, Munk A, Nielsen TS, Daughtry MR, Larsson L, Li S, Høyer KF, Geisler HW, Sulek K, Kjøbsted R, Fisher T, Andersen MM, Shen Z, Hansen UK, England EM, ... ... Yang X, et al. Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity. Molecular Metabolism. PMID 29525407 DOI: 10.1016/J.Molmet.2018.02.010  0.491
2018 MOHAN R, RUAN H, YANG X, ALEJANDRO E. Pancreatic Beta Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Streptozotocin- and High-Fat Diet–Induced Diabetes in Female Mice Diabetes. 67: 83-OR. DOI: 10.2337/Db18-83-Or  0.393
2017 Ruan HB, Ma Y, Torres S, Zhang B, Feriod C, Heck RM, Qian K, Fu M, Li X, Nathanson MH, Bennett AM, Nie Y, Ehrlich BE, Yang X. Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation. Genes & Development. PMID 28903979 DOI: 10.1101/Gad.305441.117  0.503
2017 Fu M, Yang X. The sweet tooth of the circadian clock. Biochemical Society Transactions. PMID 28673939 DOI: 10.1042/Bst20160183  0.438
2017 Yang X, Qian K. Protein O-GlcNAcylation: emerging mechanisms and functions. Nature Reviews. Molecular Cell Biology. PMID 28488703 DOI: 10.1038/Nrm.2017.22  0.591
2016 Wang S, Yang X. Inter-organ regulation of adipose tissue browning. Cellular and Molecular Life Sciences : Cmls. PMID 27866221 DOI: 10.1007/S00018-016-2420-X  0.332
2016 Zhao L, Feng Z, Yang X, Liu J. The regulatory Roles of O-GlcNAcylation in mitochondrial Homeostasis and metabolic Syndrome. Free Radical Research. 1-20. PMID 27646831 DOI: 10.1080/10715762.2016.1239017  0.49
2016 Jiang M, Qiu Z, Zhang S, Fan X, Cai X, Xu B, Li X, Zhou J, Zhang X, Chu Y, Wang W, Liang J, Horvath T, Yang X, Wu K, et al. Elevated O-GlcNAcylation promotes gastric cancer cells proliferation by modulating cell cycle related proteins and ERK 1/2 signaling. Oncotarget. PMID 27542217 DOI: 10.18632/Oncotarget.11359  0.522
2016 Xie Z, Zhang D, Chung D, Tang Z, Huang H, Dai L, Qi S, Li J, Colak G, Chen Y, Xia C, Peng C, Ruan H, Kirkey M, Wang D, ... ... Yang X, et al. Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation. Molecular Cell. 62: 194-206. PMID 27105115 DOI: 10.1016/J.Molcel.2016.03.036  0.369
2015 Bindesbøll C, Fan Q, Nørgaard RC, MacPherson L, Ruan HB, Wu J, Pedersen TÅ, Steffensen KR, Yang X, Matthews J, Mandrup S, Nebb HI, Grønning-Wang LM. Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity. Journal of Lipid Research. 56: 771-85. PMID 25724563 DOI: 10.1194/Jlr.M049130  0.563
2015 Perry RJ, Camporez JP, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, et al. Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes. Cell. 160: 745-58. PMID 25662011 DOI: 10.1016/J.Cell.2015.01.012  0.308
2015 Singh JP, Zhang K, Wu J, Yang X. O-GlcNAc signaling in cancer metabolism and epigenetics. Cancer Letters. 356: 244-50. PMID 24769077 DOI: 10.1016/J.Canlet.2014.04.014  0.545
2014 Zhang K, Yin R, Yang X. O-GlcNAc: A Bittersweet Switch in Liver. Frontiers in Endocrinology. 5: 221. PMID 25566193 DOI: 10.3389/Fendo.2014.00221  0.47
2014 Ruan HB, Dietrich MO, Liu ZW, Zimmer MR, Li MD, Singh JP, Zhang K, Yin R, Wu J, Horvath TL, Yang X. O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat. Cell. 159: 306-17. PMID 25303527 DOI: 10.1016/J.Cell.2014.09.010  0.48
2014 Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P. Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 510: 547-51. PMID 24870244 DOI: 10.1038/Nature13267  0.376
2014 Wu J, Bowe DB, Sadlonova A, Whisenhunt TR, Hu Y, Rustgi AK, Nie Y, Paterson AJ, Yang X. O-GlcNAc transferase is critical for transducin-like enhancer of split (TLE)-mediated repression of canonical Wnt signaling. The Journal of Biological Chemistry. 289: 12168-76. PMID 24616106 DOI: 10.1074/Jbc.M114.553859  0.78
2013 Ruan HB, Nie Y, Yang X. Regulation of protein degradation by O-GlcNAcylation: crosstalk with ubiquitination. Molecular & Cellular Proteomics : McP. 12: 3489-97. PMID 23824911 DOI: 10.1074/Mcp.R113.029751  0.571
2013 Ruan HB, Singh JP, Li MD, Wu J, Yang X. Cracking the O-GlcNAc code in metabolism. Trends in Endocrinology and Metabolism: Tem. 24: 301-9. PMID 23647930 DOI: 10.1016/J.Tem.2013.02.002  0.561
2013 Li MD, Ruan HB, Hughes ME, Lee JS, Singh JP, Jones SP, Nitabach MN, Yang X. O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination. Cell Metabolism. 17: 303-10. PMID 23395176 DOI: 10.1016/J.Cmet.2012.12.015  0.561
2012 Dominy JE, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, et al. The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Molecular Cell. 48: 900-13. PMID 23142079 DOI: 10.1016/J.Molcel.2012.09.030  0.399
2012 Ruan HB, Han X, Li MD, Singh JP, Qian K, Azarhoush S, Zhao L, Bennett AM, Samuel VT, Wu J, Yates JR, Yang X. O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability. Cell Metabolism. 16: 226-37. PMID 22883232 DOI: 10.1016/J.Cmet.2012.07.006  0.535
2012 Li MD, Ruan HB, Singh JP, Zhao L, Zhao T, Azarhoush S, Wu J, Evans RM, Yang X. O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression. The Journal of Biological Chemistry. 287: 12904-12. PMID 22371499 DOI: 10.1074/Jbc.M111.303792  0.557
2011 Li MD, Yang X. A Retrospective on Nuclear Receptor Regulation of Inflammation: Lessons from GR and PPARs. Ppar Research. 2011: 742785. PMID 21941526 DOI: 10.1155/2011/742785  0.32
2011 Guinez C, Filhoulaud G, Rayah-Benhamed F, Marmier S, Dubuquoy C, Dentin R, Moldes M, Burnol AF, Yang X, Lefebvre T, Girard J, Postic C. O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver. Diabetes. 60: 1399-413. PMID 21471514 DOI: 10.2337/Db10-0452  0.554
2010 Yang X. A wheel of time: the circadian clock, nuclear receptors, and physiology. Genes & Development. 24: 741-7. PMID 20395363 DOI: 10.1101/Gad.1920710  0.308
2009 Sha H, He Y, Chen H, Wang C, Zenno A, Shi H, Yang X, Zhang X, Qi L. The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis. Cell Metabolism. 9: 556-64. PMID 19490910 DOI: 10.1016/J.Cmet.2009.04.009  0.391
2008 Yang X, Ongusaha PP, Miles PD, Havstad JC, Zhang F, So WV, Kudlow JE, Michell RH, Olefsky JM, Field SJ, Evans RM. Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance. Nature. 451: 964-9. PMID 18288188 DOI: 10.1038/Nature06668  0.751
2006 Whisenhunt TR, Yang X, Bowe DB, Paterson AJ, Van Tine BA, Kudlow JE. Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development. Glycobiology. 16: 551-63. PMID 16505006 DOI: 10.1093/Glycob/Cwj096  0.748
2003 Zhang F, Su K, Yang X, Bowe DB, Paterson AJ, Kudlow JE. O-GlcNAc modification is an endogenous inhibitor of the proteasome. Cell. 115: 715-25. PMID 14675536 DOI: 10.1016/S0092-8674(03)00974-7  0.777
2002 Yang X, Zhang F, Kudlow JE. Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression. Cell. 110: 69-80. PMID 12150998 DOI: 10.1016/S0092-8674(02)00810-3  0.778
2001 Yang X, Su K, Roos MD, Chang Q, Paterson AJ, Kudlow JE. O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability Proceedings of the National Academy of Sciences of the United States of America. 98: 6611-6616. PMID 11371615 DOI: 10.1073/Pnas.111099998  0.752
2000 Su K, Yang X, Roos MD, Paterson AJ, Kudlow JE. Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1 Biochemical Journal. 348: 281-289. PMID 10816420 DOI: 10.1042/0264-6021:3480281  0.629
2000 Chang Q, Su K, Baker JR, Yang X, Paterson AJ, Kudlow JE. Phosphorylation of human glutamine:fructose-6-phosphate amidotransferase by cAMP-dependent protein kinase at serine 205 blocks the enzyme activity Journal of Biological Chemistry. 275: 21981-21987. PMID 10806197 DOI: 10.1074/Jbc.M001049200  0.676
1999 Su K, Roos MD, Yang X, Han I, Paterson AJ, Kudlow JE. An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro Journal of Biological Chemistry. 274: 15194-15202. PMID 10329728 DOI: 10.1074/Jbc.274.21.15194  0.662
1998 Roos MD, Xie W, Su K, Clark JA, Yang X, Chin E, Paterson AJ, Kudlow JE. Streptozotocin, an analog of N-acetylglucosamine, blocks the removal of O-GlcNAc from intracellular proteins Proceedings of the Association of American Physicians. 110: 422-432. PMID 9756093  0.698
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