| Year |
Citation |
Score |
| 2024 |
Sala-Rabanal M, Yurtsever Z, Berry KN, McClenaghan C, Foy AJ, Hanson A, Steinberg DF, Greven JA, Kluender CE, Alexander-Brett JM, Nichols CG, Brett TJ. Modulation of TMEM16B Channel Activity by the Calcium-Activated Chloride Channel Regulator 4 (CLCA4) in Human Cells. The Journal of Biological Chemistry. 107432. PMID 38825009 DOI: 10.1016/j.jbc.2024.107432 |
0.776 |
|
| 2020 |
Kober DL, Stuchell-Brereton MD, Kluender CE, Dean HB, Strickland MR, Steinberg DF, Nelson SS, Baban B, Holtzman DM, Frieden C, Alexander-Brett J, Roberson ED, Song Y, Brett TJ. Functional insights from biophysical study of TREM2 interactions with apoE and Aβ. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33090700 DOI: 10.1002/alz.12194 |
0.756 |
|
| 2020 |
Berry KN, Brett TJ. Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement. Cell Reports. 30: 1141-1151.e3. PMID 31995732 DOI: 10.1016/J.Celrep.2019.12.059 |
0.388 |
|
| 2019 |
Deming Y, Filipello F, Cignarella F, Cantoni C, Hsu S, Mikesell R, Li Z, Del-Aguila JL, Dube U, Farias FG, Bradley J, Budde J, Ibanez L, Fernandez MV, Blennow K, ... ... Brett TJ, et al. The gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk. Science Translational Medicine. 11. PMID 31413141 DOI: 10.1126/Scitranslmed.Aau2291 |
0.312 |
|
| 2019 |
Kober D, Kluender C, Brett T. P4-172: BIOPHYSICAL INVESTIGATION OF THE TREM2 INTERACTIONS WITH APOE AND AMYLOID BETA1-42
REVEAL TWO DISTINCT BINDING SURFACES AND A POTENTIAL ROLE FOR STREM2 AS AN INHIBITOR OF AMYLOID BETA1-42
POLYMERIZATION Alzheimer's & Dementia. 15: P1340-P1340. DOI: 10.1016/J.Jalz.2019.06.3834 |
0.715 |
|
| 2018 |
Chanthamontri CK, Jordan D, Wang W, Wu C, Lin YL, Brett TJ, Gross ML, Leung DW. Ebola Viral Protein 35 N-terminus is a Parallel Tetramer. Biochemistry. PMID 30592210 DOI: 10.1021/Acs.Biochem.8B01154 |
0.321 |
|
| 2018 |
Ohlemacher SI, Xu Y, Kober DL, Malik M, Nix JC, Brett TJ, Henderson JP. YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria. The Journal of Biological Chemistry. PMID 30355735 DOI: 10.1074/jbc.RA118.005752 |
0.735 |
|
| 2018 |
Berry KN, Kober DL, Su A, Brett TJ. Limiting Respiratory Viral Infection by Targeting Antiviral and Immunological Functions of BST-2/Tetherin: Knowledge and Gaps. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1800086. PMID 30113067 DOI: 10.1002/Bies.201800086 |
0.72 |
|
| 2017 |
Kober DL, Brett TJ. TREM2-ligand interactions in health and disease. Journal of Molecular Biology. PMID 28432014 DOI: 10.1016/J.Jmb.2017.04.004 |
0.755 |
|
| 2017 |
Sala-Rabanal M, Yurtsever Z, Berry KN, Nichols CG, Brett TJ. Modulation of TMEM16A Channel Activity by the Von Willebrand Factor Type A (VWA) domain of the Calcium-Activated Chloride Channel Regulator 1 (CLCA1). The Journal of Biological Chemistry. PMID 28420732 DOI: 10.1074/Jbc.M117.788232 |
0.784 |
|
| 2016 |
Kober DL, Alexander-Brett JM, Karch CM, Cruchaga C, Colonna M, Holtzman MJ, Brett TJ. Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms. Elife. 5. PMID 27995897 DOI: 10.7554/Elife.20391 |
0.772 |
|
| 2016 |
Yurtsever Z, Patel DA, Kober DL, Su A, Miller CA, Romero AG, Holtzman MJ, Brett TJ. First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes. Biochimica Et Biophysica Acta. PMID 27369736 DOI: 10.1016/J.Bbagen.2016.06.023 |
0.752 |
|
| 2016 |
Liu S, Feng J, Luo J, Yang P, Brett TJ, Hu H. Eact, a small molecule activator of TMEM16A, activates TRPV1 and elicits pain- and itch-related behaviors. British Journal of Pharmacology. PMID 26756551 DOI: 10.1111/Bph.13420 |
0.345 |
|
| 2016 |
Kober DL, Alexander-Brett JM, Karch CM, Cruchaga C, Colonna M, Holtzman MJ, Brett TJ. Author response: Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms Elife. DOI: 10.7554/Elife.20391.021 |
0.755 |
|
| 2016 |
Sala-Rabanal M, Yurtsever Z, Nichols CG, Brett TJ. Secreted Human CLCA1 Activates Calcium-Dependent Chloride Currents through Direct Binding of Its VWA Domain with an Extracellular Loop of TMEM16A/Anoctamin 1 Biophysical Journal. 110: 606a. DOI: 10.1016/J.Bpj.2015.11.3235 |
0.788 |
|
| 2015 |
Kober DL, Yurtsever Z, Brett TJ. Efficient Mammalian Cell Expression and Single-step Purification of Extracellular Glycoproteins for Crystallization. Journal of Visualized Experiments : Jove. e53445. PMID 26780656 DOI: 10.3791/53445 |
0.752 |
|
| 2015 |
Sala-Rabanal M, Yurtsever Z, Berry KN, Brett TJ. Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway Diseases. Mediators of Inflammation. 2015: 497387. PMID 26612971 DOI: 10.1155/2015/497387 |
0.773 |
|
| 2015 |
Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E, Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE, Paessler S, ... ... Brett TJ, et al. PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection. Nature Immunology. PMID 26479788 DOI: 10.1038/Ni.3279 |
0.307 |
|
| 2015 |
Brett TJ. CLCA1 and TMEM16A: the link towards a potential cure for airway diseases. Expert Review of Respiratory Medicine. 9: 503-6. PMID 26296094 DOI: 10.1586/17476348.2015.1081064 |
0.336 |
|
| 2015 |
Wu K, Byers DE, Jin X, Agapov E, Alexander-Brett J, Patel AC, Cella M, Gilfilan S, Colonna M, Kober DL, Brett TJ, Holtzman MJ. TREM-2 promotes macrophage survival and lung disease after respiratory viral infection. The Journal of Experimental Medicine. 212: 681-97. PMID 25897174 DOI: 10.1084/Jem.20141732 |
0.758 |
|
| 2015 |
Yurtsever Z, Scheaffer SM, Romero AG, Holtzman MJ, Brett TJ. The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation. Acta Crystallographica. Section D, Biological Crystallography. 71: 790-9. PMID 25849390 DOI: 10.1107/S1399004715001212 |
0.754 |
|
| 2015 |
Sala-Rabanal M, Yurtsever Z, Nichols CG, Brett TJ. Secreted CLCA1 modulates TMEM16A to activate Ca(2+)-dependent chloride currents in human cells. Elife. 4. PMID 25781344 DOI: 10.7554/Elife.05875 |
0.784 |
|
| 2015 |
Sala-Rabanal M, Yurtsever Z, Nichols CG, Brett TJ. Author response: Secreted CLCA1 modulates TMEM16A to activate Ca2+-dependent chloride currents in human cells Elife. DOI: 10.7554/Elife.05875.010 |
0.75 |
|
| 2015 |
Sala-Rabanal M, Yurtsever Z, Berry KN, Brett TJ. Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway Diseases Mediators of Inflammation. 2015. DOI: 10.1155/2015/497387 |
0.762 |
|
| 2015 |
Sala-Rabanal M, Yurtsever Z, Nichols CG, Brett TJ. Secreted Human CLCA1 Activates Calcium-Dependent Chloride Currents via Interaction with TMEM16A (Anoctamin 1) Biophysical Journal. 108: 435a. DOI: 10.1016/J.Bpj.2014.11.2376 |
0.786 |
|
| 2014 |
Kober DL, Wanhainen KM, Johnson BM, Randolph DT, Holtzman MJ, Brett TJ. Preparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseases. Protein Expression and Purification. 96: 32-8. PMID 24508568 DOI: 10.1016/J.Pep.2014.01.015 |
0.769 |
|
| 2014 |
Kober D, Brett T. Structural Studies of TREM-2 Mutants Linked to Neurodegenerative Diseases Acta Crystallographica Section a Foundations and Advances. 70: C248-C248. DOI: 10.1107/S2053273314097514 |
0.774 |
|
| 2014 |
Yurtsever Z, Sala-Rabanal M, Nichols CG, Brett TJ. Mechanism of CLCA1-Mediated CACC Activation in Chronic Lung Diseases Biophysical Journal. 106: 751a. DOI: 10.1016/J.Bpj.2013.11.4136 |
0.786 |
|
| 2013 |
Combs MD, Knutsen RH, Broekelmann TJ, Toennies HM, Brett TJ, Miller CA, Kober DL, Craft CS, Atkinson JJ, Shipley JM, Trask BC, Mecham RP. Microfibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivo. The Journal of Biological Chemistry. 288: 28869-80. PMID 23963447 DOI: 10.1074/Jbc.M113.497727 |
0.73 |
|
| 2013 |
Swiecki M, Omattage NS, Brett TJ. BST-2/tetherin: structural biology, viral antagonism, and immunobiology of a potent host antiviral factor. Molecular Immunology. 54: 132-9. PMID 23274150 DOI: 10.1016/J.Molimm.2012.11.008 |
0.318 |
|
| 2012 |
Alevy YG, Patel AC, Romero AG, Patel DA, Tucker J, Roswit WT, Miller CA, Heier RF, Byers DE, Brett TJ, Holtzman MJ. IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. The Journal of Clinical Investigation. 122: 4555-68. PMID 23187130 DOI: 10.1172/Jci64896 |
0.346 |
|
| 2012 |
Yurtsever Z, Sala-Rabanal M, Randolph DT, Scheaffer SM, Roswit WT, Alevy YG, Patel AC, Heier RF, Romero AG, Nichols CG, Holtzman MJ, Brett TJ. Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation. The Journal of Biological Chemistry. 287: 42138-49. PMID 23112050 DOI: 10.1074/Jbc.M112.410282 |
0.788 |
|
| 2012 |
Doray B, Misra S, Qian Y, Brett TJ, Kornfeld S. Do GGA adaptors bind internal DXXLL motifs? Traffic (Copenhagen, Denmark). 13: 1315-25. PMID 22762444 DOI: 10.1111/J.1600-0854.2012.01396.X |
0.349 |
|
| 2011 |
Swiecki M, Scheaffer SM, Allaire M, Fremont DH, Colonna M, Brett TJ. Structural and biophysical analysis of BST-2/tetherin ectodomains reveals an evolutionary conserved design to inhibit virus release. The Journal of Biological Chemistry. 286: 2987-97. PMID 21084286 DOI: 10.1074/Jbc.M110.190538 |
0.546 |
|
| 2009 |
Patel AC, Brett TJ, Holtzman MJ. The role of CLCA proteins in inflammatory airway disease. Annual Review of Physiology. 71: 425-49. PMID 18954282 DOI: 10.1146/Annurev.Physiol.010908.163253 |
0.41 |
|
| 2006 |
Brett TJ, Legendre-Guillemin V, McPherson PS, Fremont DH. Structural definition of the F-actin-binding THATCH domain from HIP1R. Nature Structural & Molecular Biology. 13: 121-30. PMID 16415883 DOI: 10.1038/Nsmb1043 |
0.547 |
|
| 2004 |
Mishra SK, Hawryluk MJ, Brett TJ, Keyel PA, Dupin AL, Jha A, Heuser JE, Fremont DH, Traub LM. Dual engagement regulation of protein interactions with the AP-2 adaptor alpha appendage. The Journal of Biological Chemistry. 279: 46191-203. PMID 15292237 DOI: 10.1074/Jbc.M408095200 |
0.542 |
|
| 2004 |
Ota N, Brett TJ, Murphy TL, Fremont DH, Murphy KM. N-domain-dependent nonphosphorylated STAT4 dimers required for cytokine-driven activation. Nature Immunology. 5: 208-15. PMID 14704793 DOI: 10.1038/Ni1032 |
0.556 |
|
| 2002 |
Alexander JM, Nelson CA, van Berkel V, Lau EK, Studts JM, Brett TJ, Speck SH, Handel TM, Virgin HW, Fremont DH. Structural basis of chemokine sequestration by a herpesvirus decoy receptor. Cell. 111: 343-56. PMID 12419245 DOI: 10.1016/S0092-8674(02)01007-3 |
0.544 |
|
| 2002 |
Brett TJ, Traub LM, Fremont DH. Accessory protein recruitment motifs in clathrin-mediated endocytosis. Structure (London, England : 1993). 10: 797-809. PMID 12057195 DOI: 10.1016/S0969-2126(02)00784-0 |
0.557 |
|
| 2002 |
Alexander JM, Clark JL, Brett TJ, Stezowski JJ. Chiral discrimination in cyclodextrin complexes of amino acid derivatives: beta-cyclodextrin/N-acetyl-L-phenylalanine and N-acetyl-D-phenylalanine complexes. Proceedings of the National Academy of Sciences of the United States of America. 99: 5115-20. PMID 11943858 DOI: 10.1073/Pnas.072647599 |
0.653 |
|
| 2001 |
Mishra SK, Agostinelli NR, Brett TJ, Mizukami I, Ross TS, Traub LM. Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins. The Journal of Biological Chemistry. 276: 46230-6. PMID 11577110 DOI: 10.1074/Jbc.M108177200 |
0.306 |
|
| 2001 |
Rajca A, Wang H, Pawitranon V, Brett TJ, Stezowski JJ. Synthesis and structure of tetrathiophene with a chiral 1,1′-binaphthyl kink Chemical Communications. 1060-1061. DOI: 10.1039/B007355P |
0.516 |
|
| 2000 |
Brett TJ, Stezowski JJ. Structural studies of supramolecular β-cyclodextrin complexes with butyrophenone and valerophenone: An explanation for photochemical reaction modification Chemical Communications. 857-858. DOI: 10.1039/B002828M |
0.527 |
|
| 2000 |
Brett TJ, Alexander JM, Stezowski JJ. Chemical insight from crystallographic disorder-structural studies of supramolecular photochemical systems. Part 3. The β-cyclodextrin-7-hydroxy-4-methylcoumarin inclusion complex: Direct observation of photodimerization by X-ray crystallography Journal of the Chemical Society. Perkin Transactions 2. 1105-1111. DOI: 10.1039/A906042A |
0.54 |
|
| 2000 |
Brett TJ, Alexander JM, Stezowski JJ. Chemical insight from crystallographic disorder-structural studies of supramolecular photochemical systems. Part 2. The β-cyclodextrin-4,7-dimethylcoumarin inclusion complex: A new β-cyclodextrin dimer packing type, unanticipated photoproduct formation, and an examination of guest influence on β-CD dimer packing Journal of the Chemical Society. Perkin Transactions 2. 1095-1103. DOI: 10.1039/A906041C |
0.539 |
|
| 1999 |
Brett TJ, Alexander JM, Clark JL, Ross CR, Harbison GS, Stezowski JJ. Chemical insight from crystallographic disorder: Structural studies of a supramolecular β-cyclodextrin/coumarin photochemical system Chemical Communications. 1275-1276. DOI: 10.1039/A902092F |
0.641 |
|
| 1999 |
Brett TJ, Liu S, Coppens P, Stezowski JJ. The 20 K structure of p-amino-p'-nitrobiphenyl in the non-constraining environment of its β-cyclodextrin inclusion complex Chemical Communications. 551-552. DOI: 10.1039/A808832B |
0.524 |
|
| 1996 |
Brett TJ, Stezowski JJ, Selbo KM, Ross II CR, Zeng Q, Kurtz DM, Scott RA. Crystal structures ofClostridium pasteurianumrubredoxin mutants V8A and V8N Acta Crystallographica Section a Foundations of Crystallography. 52: C71-C71. DOI: 10.1107/S0108767396096213 |
0.541 |
|
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