| Year |
Citation |
Score |
| 2021 |
Jeancolas C, Matsubara YJ, Vybornyi M, Lambert CN, Blokhuis A, Alline T, Griffiths AD, Ameta S, Krishna S, Nghe P. RNA diversification by a self-reproducing ribozyme revealed by deep sequencing and kinetic modelling. Chemical Communications (Cambridge, England). PMID 34235521 DOI: 10.1039/d1cc02290c |
0.676 |
|
| 2020 |
Bounab Y, Eyer K, Dixneuf S, Rybczynska M, Chauvel C, Mistretta M, Tran T, Aymerich N, Chenon G, Llitjos JF, Venet F, Monneret G, Gillespie IA, Cortez P, Moucadel V, ... ... Griffiths AD, et al. Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap. Nature Protocols. PMID 32788719 DOI: 10.1038/S41596-020-0354-0 |
0.357 |
|
| 2020 |
Gérard A, Woolfe A, Mottet G, Reichen M, Castrillon C, Menrath V, Ellouze S, Poitou A, Doineau R, Briseno-Roa L, Canales-Herrerias P, Mary P, Rose G, Ortega C, Delincé M, ... ... Griffiths AD, et al. Author Correction: High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics. Nature Biotechnology. PMID 32444853 DOI: 10.1038/S41587-020-0563-7 |
0.37 |
|
| 2020 |
Gérard A, Woolfe A, Mottet G, Reichen M, Castrillon C, Menrath V, Ellouze S, Poitou A, Doineau R, Briseno-Roa L, Canales-Herrerias P, Mary P, Rose G, Ortega C, Delincé M, ... ... Griffiths AD, et al. High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics. Nature Biotechnology. PMID 32231335 DOI: 10.1038/S41587-020-0466-7 |
0.359 |
|
| 2018 |
Arsène S, Ameta S, Lehman N, Griffiths AD, Nghe P. Coupled catabolism and anabolism in autocatalytic RNA sets. Nucleic Acids Research. PMID 29982824 DOI: 10.1093/Nar/Gky598 |
0.349 |
|
| 2017 |
Eyer K, Doineau RCL, Castrillon CE, Briseño-Roa L, Menrath V, Mottet G, England P, Godina A, Brient-Litzler E, Nizak C, Jensen A, Griffiths AD, Bibette J, Bruhns P, Baudry J. Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring. Nature Biotechnology. PMID 28892076 DOI: 10.1038/Nbt.3964 |
0.326 |
|
| 2017 |
Obexer R, Pott M, Zeymer C, Griffiths AD, Hilvert D. Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting. Protein Engineering, Design & Selection : Peds. 30: 531. PMID 28873983 DOI: 10.1093/Protein/Gzx032 |
0.337 |
|
| 2017 |
Fenneteau J, Chauvin D, Griffiths AD, Nizak C, Cossy J. Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays. Chemical Communications (Cambridge, England). PMID 28462964 DOI: 10.1039/C7Cc01506B |
0.425 |
|
| 2017 |
Beneyton T, Thomas S, Griffiths AD, Nicaud JM, Drevelle A, Rossignol T. Droplet-based microfluidic high-throughput screening of heterologous enzymes secreted by the yeast Yarrowia lipolytica. Microbial Cell Factories. 16: 18. PMID 28143479 DOI: 10.1186/S12934-017-0629-5 |
0.417 |
|
| 2017 |
Obexer R, Godina A, Garrabou X, Mittl PR, Baker D, Griffiths AD, Hilvert D. Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase. Nature Chemistry. 9: 50-56. PMID 27995916 DOI: 10.1038/Nchem.2596 |
0.377 |
|
| 2016 |
Matsumura S, Kun Á, Ryckelynck M, Coldren F, Szilágyi A, Jossinet F, Rick C, Nghe P, Szathmáry E, Griffiths AD. Transient compartmentalization of RNA replicators prevents extinction due to parasites. Science (New York, N.Y.). 354: 1293-1296. PMID 27940874 DOI: 10.1126/Science.Aag1582 |
0.738 |
|
| 2016 |
Obexer R, Pott M, Zeymer C, Griffiths AD, Hilvert D. Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting. Protein Engineering, Design & Selection : Peds. PMID 27542390 DOI: 10.1093/Protein/Gzw032 |
0.4 |
|
| 2016 |
Beneyton T, Wijaya IP, Postros P, Najah M, Leblond P, Couvent A, Mayot E, Griffiths AD, Drevelle A. High-throughput screening of filamentous fungi using nanoliter-range droplet-based microfluidics. Scientific Reports. 6: 27223. PMID 27270141 DOI: 10.1038/Srep27223 |
0.39 |
|
| 2016 |
Cottinet D, Condamine F, Bremond N, Griffiths AD, Rainey PB, de Visser JA, Baudry J, Bibette J. Lineage Tracking for Probing Heritable Phenotypes at Single-Cell Resolution. Plos One. 11: e0152395. PMID 27077662 DOI: 10.1371/Journal.Pone.0152395 |
0.359 |
|
| 2015 |
Woronoff G, Ryckelynck M, Wessel J, Schicke O, Griffiths AD, Soumillion P. Activity-Fed Translation (AFT) Assay: A New High-Throughput Screening Strategy for Enzymes in Droplets. Chembiochem : a European Journal of Chemical Biology. 16: 1343-9. PMID 25914325 DOI: 10.1002/Cbic.201500087 |
0.78 |
|
| 2015 |
Ryckelynck M, Baudrey S, Rick C, Marin A, Coldren F, Westhof E, Griffiths AD. Using droplet-based microfluidics to improve the catalytic properties of RNA under multiple-turnover conditions. Rna (New York, N.Y.). 21: 458-69. PMID 25605963 DOI: 10.1261/Rna.048033.114 |
0.775 |
|
| 2015 |
Leman M, Abouakil F, Griffiths AD, Tabeling P. Droplet-based microfluidics at the femtolitre scale. Lab On a Chip. 15: 753-65. PMID 25428861 DOI: 10.1039/C4Lc01122H |
0.355 |
|
| 2014 |
Najah M, Calbrix R, Mahendra-Wijaya IP, Beneyton T, Griffiths AD, Drevelle A. Droplet-based microfluidics platform for ultra-high-throughput bioprospecting of cellulolytic microorganisms. Chemistry & Biology. 21: 1722-32. PMID 25525991 DOI: 10.1016/J.Chembiol.2014.10.020 |
0.425 |
|
| 2014 |
Beneyton T, Coldren F, Baret JC, Griffiths AD, Taly V. CotA laccase: high-throughput manipulation and analysis of recombinant enzyme libraries expressed in E. coli using droplet-based microfluidics. The Analyst. 139: 3314-23. PMID 24733162 DOI: 10.1039/C4An00228H |
0.41 |
|
| 2013 |
Najah M, Mayot E, Mahendra-Wijaya IP, Griffiths AD, Ladame S, Drevelle A. New glycosidase substrates for droplet-based microfluidic screening. Analytical Chemistry. 85: 9807-14. PMID 24079367 DOI: 10.1021/Ac4022709 |
0.434 |
|
| 2013 |
Taly V, Pekin D, Benhaim L, Kotsopoulos SK, Le Corre D, Li X, Atochin I, Link DR, Griffiths AD, Pallier K, Blons H, Bouché O, Landi B, Hutchison JB, Laurent-Puig P. Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients. Clinical Chemistry. 59: 1722-31. PMID 23938455 DOI: 10.1373/Clinchem.2013.206359 |
0.304 |
|
| 2013 |
Mazutis L, Gilbert J, Ung WL, Weitz DA, Griffiths AD, Heyman JA. Single-cell analysis and sorting using droplet-based microfluidics. Nature Protocols. 8: 870-91. PMID 23558786 DOI: 10.1038/Nprot.2013.046 |
0.406 |
|
| 2012 |
Sepp A, Griffiths A. Cell-free selection of domain antibodies by in vitro compartmentalization. Methods in Molecular Biology (Clifton, N.J.). 911: 183-98. PMID 22886253 DOI: 10.1007/978-1-61779-968-6_12 |
0.366 |
|
| 2012 |
El Debs B, Utharala R, Balyasnikova IV, Griffiths AD, Merten CA. Functional single-cell hybridoma screening using droplet-based microfluidics. Proceedings of the National Academy of Sciences of the United States of America. 109: 11570-5. PMID 22753519 DOI: 10.1073/Pnas.1204514109 |
0.398 |
|
| 2012 |
Mazutis L, Griffiths AD. Selective droplet coalescence using microfluidic systems. Lab On a Chip. 12: 1800-6. PMID 22453914 DOI: 10.1039/C2Lc40121E |
0.364 |
|
| 2012 |
Theberge AB, Mayot E, El Harrak A, Kleinschmidt F, Huck WT, Griffiths AD. Microfluidic platform for combinatorial synthesis in picolitre droplets. Lab On a Chip. 12: 1320-6. PMID 22344399 DOI: 10.1039/C2Lc21019C |
0.403 |
|
| 2012 |
Fallah-Araghi A, Baret JC, Ryckelynck M, Griffiths AD. A completely in vitro ultrahigh-throughput droplet-based microfluidic screening system for protein engineering and directed evolution. Lab On a Chip. 12: 882-91. PMID 22277990 DOI: 10.1039/C2Lc21035E |
0.78 |
|
| 2012 |
Najah M, Griffiths AD, Ryckelynck M. Teaching single-cell digital analysis using droplet-based microfluidics. Analytical Chemistry. 84: 1202-9. PMID 22229495 DOI: 10.1021/Ac202645M |
0.763 |
|
| 2012 |
Miller OJ, El Harrak A, Mangeat T, Baret JC, Frenz L, El Debs B, Mayot E, Samuels ML, Rooney EK, Dieu P, Galvan M, Link DR, Griffiths AD. High-resolution dose-response screening using droplet-based microfluidics. Proceedings of the National Academy of Sciences of the United States of America. 109: 378-83. PMID 22203966 DOI: 10.1073/Pnas.1113324109 |
0.322 |
|
| 2011 |
El Debs BW, Tschulena U, Griffiths AD, Merten CA. A competitive co-cultivation assay for cancer drug specificity evaluation. Journal of Biomolecular Screening. 16: 818-24. PMID 21788393 DOI: 10.1177/1087057111414898 |
0.333 |
|
| 2011 |
Pekin D, Skhiri Y, Baret JC, Le Corre D, Mazutis L, Salem CB, Millot F, El Harrak A, Hutchison JB, Larson JW, Link DR, Laurent-Puig P, Griffiths AD, Taly V. Quantitative and sensitive detection of rare mutations using droplet-based microfluidics. Lab On a Chip. 11: 2156-66. PMID 21594292 DOI: 10.1039/C1Lc20128J |
0.345 |
|
| 2011 |
Zhong Q, Bhattacharya S, Kotsopoulos S, Olson J, Taly V, Griffiths AD, Link DR, Larson JW. Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR. Lab On a Chip. 11: 2167-74. PMID 21584334 DOI: 10.1039/C1Lc20126C |
0.401 |
|
| 2011 |
Woronoff G, El Harrak A, Mayot E, Schicke O, Miller OJ, Soumillion P, Griffiths AD, Ryckelynck M. New generation of amino coumarin methyl sulfonate-based fluorogenic substrates for amidase assays in droplet-based microfluidic applications. Analytical Chemistry. 83: 2852-7. PMID 21413778 DOI: 10.1021/Ac200373N |
0.775 |
|
| 2011 |
Briseño-Roa L, Oliynyk Z, Timperley CM, Griffiths AD, Fersht AR. Highest paraoxonase turnover rate found in a bacterial phosphotriesterase variant. Protein Engineering, Design & Selection : Peds. 24: 209-11. PMID 20650962 DOI: 10.1093/Protein/Gzq046 |
0.342 |
|
| 2010 |
Vyawahare S, Griffiths AD, Merten CA. Miniaturization and parallelization of biological and chemical assays in microfluidic devices. Chemistry & Biology. 17: 1052-65. PMID 21035727 DOI: 10.1016/J.Chembiol.2010.09.007 |
0.388 |
|
| 2010 |
Baret JC, Beck Y, Billas-Massobrio I, Moras D, Griffiths AD. Quantitative cell-based reporter gene assays using droplet-based microfluidics. Chemistry & Biology. 17: 528-36. PMID 20534350 DOI: 10.1016/J.Chembiol.2010.04.010 |
0.406 |
|
| 2010 |
Clausell-Tormos J, Griffiths AD, Merten CA. An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries. Lab On a Chip. 10: 1302-7. PMID 20445884 DOI: 10.1039/B921754A |
0.406 |
|
| 2010 |
Granieri L, Baret JC, Griffiths AD, Merten CA. High-throughput screening of enzymes by retroviral display using droplet-based microfluidics. Chemistry & Biology. 17: 229-35. PMID 20338514 DOI: 10.1016/J.Chembiol.2010.02.011 |
0.441 |
|
| 2010 |
Clausell-Tormos J, Griffiths AD, Merten CA. Coupling the inhibition of viral transduction with a positive fluorescence signal. Combinatorial Chemistry & High Throughput Screening. 13: 352-7. PMID 20156147 DOI: 10.2174/138620710791054312 |
0.339 |
|
| 2010 |
Agresti JJ, Antipov E, Abate AR, Ahn K, Rowat AC, Baret JC, Marquez M, Klibanov AM, Griffiths AD, Weitz DA. Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proceedings of the National Academy of Sciences of the United States of America. 107: 4004-9. PMID 20142500 DOI: 10.1073/Pnas.0910781107 |
0.423 |
|
| 2009 |
Mazutis L, Baret JC, Treacy P, Skhiri Y, Araghi AF, Ryckelynck M, Taly V, Griffiths AD. Multi-step microfluidic droplet processing: kinetic analysis of an in vitro translated enzyme. Lab On a Chip. 9: 2902-8. PMID 19789742 DOI: 10.1039/B907753G |
0.784 |
|
| 2009 |
Mazutis L, Baret JC, Griffiths AD. A fast and efficient microfluidic system for highly selective one-to-one droplet fusion. Lab On a Chip. 9: 2665-72. PMID 19704982 DOI: 10.1039/B903608C |
0.348 |
|
| 2009 |
Baret JC, Taly V, Ryckelynck M, Merten CA, Griffiths AD. [Droplets and emulsions: very high-throughput screening in biology]. Medecine Sciences : M/S. 25: 627-32. PMID 19602361 DOI: 10.1051/Medsci/2009256-7627 |
0.782 |
|
| 2009 |
Baret JC, Miller OJ, Taly V, Ryckelynck M, El-Harrak A, Frenz L, Rick C, Samuels ML, Hutchison JB, Agresti JJ, Link DR, Weitz DA, Griffiths AD. Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity. Lab On a Chip. 9: 1850-8. PMID 19532959 DOI: 10.1039/B902504A |
0.764 |
|
| 2009 |
Mazutis L, Araghi AF, Miller OJ, Baret JC, Frenz L, Janoshazi A, Taly V, Miller BJ, Hutchison JB, Link D, Griffiths AD, Ryckelynck M. Droplet-based microfluidic systems for high-throughput single DNA molecule isothermal amplification and analysis. Analytical Chemistry. 81: 4813-21. PMID 19518143 DOI: 10.1021/Ac900403Z |
0.751 |
|
| 2009 |
Granieri L, Miller OJ, Griffiths AD, Merten CA. A competition-based assay for the screening of species-specific antibiotics. The Journal of Antimicrobial Chemotherapy. 64: 62-8. PMID 19401303 DOI: 10.1093/Jac/Dkp137 |
0.354 |
|
| 2009 |
Mazutis L, Griffiths AD. Preparation of monodisperse emulsions by hydrodynamic size fractionation Applied Physics Letters. 95: 204103. DOI: 10.1063/1.3250432 |
0.343 |
|
| 2008 |
Köster S, Angilè FE, Duan H, Agresti JJ, Wintner A, Schmitz C, Rowat AC, Merten CA, Pisignano D, Griffiths AD, Weitz DA. Drop-based microfluidic devices for encapsulation of single cells. Lab On a Chip. 8: 1110-5. PMID 18584086 DOI: 10.1039/B802941E |
0.362 |
|
| 2008 |
Clausell-Tormos J, Lieber D, Baret JC, El-Harrak A, Miller OJ, Frenz L, Blouwolff J, Humphry KJ, Köster S, Duan H, Holtze C, Weitz DA, Griffiths AD, Merten CA. Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms. Chemistry & Biology. 15: 427-37. PMID 18482695 DOI: 10.1016/J.Chembiol.2008.04.004 |
0.437 |
|
| 2007 |
Kelly BT, Baret JC, Taly V, Griffiths AD. Miniaturizing chemistry and biology in microdroplets Chemical Communications. 1773-1788. PMID 17476389 DOI: 10.1039/B616252E |
0.414 |
|
| 2007 |
Taly V, Kelly BT, Griffiths AD. Droplets as microreactors for high-throughput biology Chembiochem. 8: 263-272. PMID 17226878 DOI: 10.1002/Cbic.200600425 |
0.391 |
|
| 2006 |
Griffiths AD, Tawfik DS. Miniaturising the laboratory in emulsion droplets. Trends in Biotechnology. 24: 395-402. PMID 16843558 DOI: 10.1016/J.Tibtech.2006.06.009 |
0.388 |
|
| 2006 |
Miller OJ, Bernath K, Agresti JJ, Amitai G, Kelly BT, Mastrobattista E, Taly V, Magdassi S, Tawfik DS, Griffiths AD. Directed evolution by in vitro compartmentalization. Nature Methods. 3: 561-70. PMID 16791215 DOI: 10.1038/Nmeth897 |
0.352 |
|
| 2006 |
Williams R, Peisajovich SG, Miller OJ, Magdassi S, Tawfik DS, Griffiths AD. Amplification of complex gene libraries by emulsion PCR. Nature Methods. 3: 545-50. PMID 16791213 DOI: 10.1038/Nmeth896 |
0.31 |
|
| 2005 |
Mastrobattista E, Taly V, Chanudet E, Treacy P, Kelly BT, Griffiths AD. High-throughput screening of enzyme libraries: in vitro evolution of a beta-galactosidase by fluorescence-activated sorting of double emulsions. Chemistry & Biology. 12: 1291-300. PMID 16356846 DOI: 10.1016/J.Chembiol.2005.09.016 |
0.385 |
|
| 2005 |
Agresti JJ, Kelly BT, Jäschke A, Griffiths AD. Selection of ribozymes that multiple-turnover Diels-Alder cycloadditions by using in vitro compartmentalization Proceedings of the National Academy of Sciences of the United States of America. 102: 16170-16175. PMID 16260754 DOI: 10.1073/Pnas.0503733102 |
0.396 |
|
| 2005 |
Leemhuis H, Stein V, Griffiths AD, Hollfelder F. New genotype-phenotype linkages for directed evolution of functional proteins. Current Opinion in Structural Biology. 15: 472-8. PMID 16043338 DOI: 10.1016/J.Sbi.2005.07.006 |
0.325 |
|
| 2005 |
Aharoni A, Griffiths AD, Tawfik DS. High-throughput screens and selections of enzyme-encoding genes. Current Opinion in Chemical Biology. 9: 210-6. PMID 15811807 DOI: 10.1016/J.Cbpa.2005.02.002 |
0.38 |
|
| 2004 |
Cohen HM, Tawfik DS, Griffiths AD. Altering the sequence specificity of HaeIII methyltransferase by directed evolution using in vitro compartmentalization. Protein Engineering, Design & Selection : Peds. 17: 3-11. PMID 14985532 DOI: 10.1093/Protein/Gzh001 |
0.319 |
|
| 2004 |
Bernath K, Hai M, Mastrobattista E, Griffiths AD, Magdassi S, Tawfik DS. In vitro compartmentalization by double emulsions: sorting and gene enrichment by fluorescence activated cell sorting. Analytical Biochemistry. 325: 151-7. PMID 14715296 DOI: 10.1016/J.Ab.2003.10.005 |
0.371 |
|
| 2003 |
Griffiths AD, Tawfik DS. Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization. The Embo Journal. 22: 24-35. PMID 12505981 DOI: 10.1093/Emboj/Cdg014 |
0.408 |
|
| 2002 |
Sepp A, Tawfik DS, Griffiths AD. Microbead display by in vitro compartmentalisation: selection for binding using flow cytometry. Febs Letters. 532: 455-8. PMID 12482612 DOI: 10.1016/S0014-5793(02)03740-7 |
0.336 |
|
| 2002 |
Lee YF, Tawfik DS, Griffiths AD. Investigating the target recognition of DNA cytosine-5 methyltransferase Hhal by library selection using in vitro compartmentalisation Nucleic Acids Research. 30: 4937-4944. PMID 12433997 DOI: 10.1093/Nar/Gkf617 |
0.337 |
|
| 2000 |
Griffiths AD, Tawfik DS. Man-made enzymes - From design to in vitro compartmentalisation Current Opinion in Biotechnology. 11: 338-353. PMID 10975453 DOI: 10.1016/S0958-1669(00)00109-9 |
0.36 |
|
| 1998 |
Tawfik DS, Griffiths AD. Man-made cell-like compartments for molecular evolution Nature Biotechnology. 16: 652-656. PMID 9661199 DOI: 10.1038/Nbt0798-652 |
0.374 |
|
| 1998 |
Smith GP, Patel SU, Windass JD, Thornton JM, Winter G, Griffiths AD. Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage. Journal of Molecular Biology. 277: 317-32. PMID 9514763 DOI: 10.1006/Jmbi.1997.1621 |
0.301 |
|
| 1996 |
de Wildt RM, Finnern R, Ouwehand WH, Griffiths AD, van Venrooij WJ, Hoet RM. Characterization of human variable domain antibody fragments against the U1 RNA-associated A protein, selected from a synthetic and patient-derived combinatorial V gene library. European Journal of Immunology. 26: 629-39. PMID 8605931 DOI: 10.1002/Eji.1830260319 |
0.313 |
|
| 1993 |
Griffiths A, Malmqvist M, Marks J, Bye J, Embleton M, McCafferty J, Baier M, Holliger K, Gorick B, Hughes-Jones N. Human anti-self antibodies with high specificity from phage display libraries. The Embo Journal. 12: 725-734. DOI: 10.1002/J.1460-2075.1993.Tb05706.X |
0.305 |
|
| 1991 |
McCafferty J, Griffiths AD, Winter G, Chiswell DJ. Phage antibodies: filamentous phage displaying antibody variable domains. Nature. 348: 552-4. PMID 2247164 DOI: 10.1038/348552A0 |
0.315 |
|
| 1991 |
Marks JD, Hoogenboom HR, Bonnert TP, McCafferty J, Griffiths AD, Winter G. By-passing immunization. Human antibodies from V-gene libraries displayed on phage Journal of Molecular Biology. 222: 581-597. PMID 1748994 DOI: 10.1016/0022-2836(91)90498-U |
0.303 |
|
| 1987 |
Griffiths AD, Potter BV, Eperon IC. Stereospecificity of nucleases towards phosphorothioate-substituted RNA: stereochemistry of transcription by T7 RNA polymerase. Nucleic Acids Research. 15: 4145-62. PMID 2438652 DOI: 10.1093/Nar/15.10.4145 |
0.635 |
|
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