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Idlir Liko, DPhil - Publications

Affiliations: 
2012-2018 Chemistry University of Oxford, Oxford, United Kingdom 
Area:
Native Mass Spectrometry, Membrane Proteins
Website:
https://omass.com/our-team/
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Lutomski CA, Bennett JL, El-Baba TJ, Wu D, Hinkle JD, Burnap SA, Liko I, Mullen C, Syka JEP, Struwe WB, Robinson CV. Defining proteoform-specific interactions for drug targeting in a native cell signalling environment. Nature Chemistry. PMID 39806141 DOI: 10.1038/s41557-024-01711-w  0.597
2024 Sokratous K, Cooper-Shepherd DA, Ujma J, Qu F, Giles K, Ben-Younis A, Hensen M, Langridge JI, Gault J, Jazayeri A, Liko I, Hopper JTS. Enhanced Declustering Enables Native Top-Down Analysis of Membrane Protein Complexes using Ion-Mobility Time-Aligned Fragmentation. Journal of the American Society For Mass Spectrometry. PMID 39007842 DOI: 10.1021/jasms.4c00190  0.461
2023 Lutomski CA, El-Baba TJ, Hinkle JD, Liko I, Bennett JL, Kalmankar NV, Dolan A, Kirschbaum C, Greis K, Urner LH, Kapoor P, Yen HY, Pagel K, Mullen C, Syka JEP, et al. Infrared Multiphoton Dissociation Enables Top-Down Characterization of Membrane Protein Complexes and G Protein-Coupled Receptors. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 135: e202305694. PMID 38516403 DOI: 10.1002/ange.202305694  0.651
2023 Lutomski CA, El-Baba TJ, Hinkle JD, Liko I, Bennett JL, Kalmankar NV, Dolan A, Kirschbaum C, Greis K, Urner L, Kapoor P, Yen HY, Pagel K, Mullen C, Syka JEP, et al. Infrared Multiphoton Dissociation Enables Top-Down Characterization of Membrane Protein Complexes and G Protein-Coupled Receptors. Angewandte Chemie (International Ed. in English). e202305694. PMID 37329506 DOI: 10.1002/anie.202305694  0.649
2022 Yen HY, Liko I, Song W, Kapoor P, Almeida F, Toporowska J, Gherbi K, Hopper JTS, Charlton SJ, Politis A, Sansom MSP, Jazayeri A, Robinson CV. Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor. Nature Chemistry. PMID 36357787 DOI: 10.1038/s41557-022-01041-9  0.476
2022 Urner LH, Liko I, Pagel K, Haag R, Robinson CV. Non-ionic hybrid detergents for protein delipidation. Biochimica Et Biophysica Acta. Biomembranes. 183958. PMID 35551920 DOI: 10.1016/j.bbamem.2022.183958  0.6
2022 Yen HY, Abramsson ML, Agasid MT, Lama D, Gault J, Liko I, Kaldmäe M, Saluri M, Qureshi AA, Suades A, Drew D, Degiacomi MT, Marklund EG, Allison TM, Robinson CV, et al. Electrospray ionization of native membrane proteins proceeds a charge equilibration step. Rsc Advances. 12: 9671-9680. PMID 35424940 DOI: 10.1039/d2ra01282k  0.6
2021 Quetschlich D, Esser TK, Newport TD, Fiorentino F, Shutin D, Chen S, Davis R, Lovera S, Liko I, Stansfeld PJ, Robinson CV. NaViA: A Program for the Visual Analysis of Complex Mass Spectra. Bioinformatics (Oxford, England). PMID 34145888 DOI: 10.1093/bioinformatics/btab436  0.463
2021 Chi G, Ebenhoch R, Man H, Tang H, Tremblay LE, Reggiano G, Qiu X, Bohstedt T, Liko I, Almeida FG, Garneau AP, Wang D, McKinley G, Moreau CP, Bountra KD, et al. Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. The Embo Journal. e107294. PMID 34031912 DOI: 10.15252/embj.2020107294  0.384
2020 Urner LH, Schulze M, Maier YB, Hoffmann W, Warnke S, Liko I, Folmert K, Manz C, Robinson CV, Haag R, Pagel K. A new azobenzene-based design strategy for detergents in membrane protein research. Chemical Science. 11: 3538-3546. PMID 34109026 DOI: 10.1039/d0sc01022g  0.609
2020 Yen HY, Liko I, Gault J, Wu D, Struwe WB, Robinson CV. Correlating Glycoforms of DC-SIGN with Stability Using a Combination of Enzymatic Digestion and Ion Mobility Mass Spectrometry. Angewandte Chemie (International Ed. in English). 59: 15560-15564. PMID 33462887 DOI: 10.1002/Anie.202005727  0.516
2020 Urner LH, Goltsche K, Selent M, Liko I, Schweder MP, Robinson CV, Pagel K, Haag R. Dendritic oligoglycerol regioisomer mixtures and their utility for membrane protein research. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33026114 DOI: 10.1002/chem.202003991  0.531
2020 Gault J, Liko I, Landreh M, Shutin D, Bolla JR, Jefferies D, Agasid M, Yen HY, Ladds MJGW, Lane DP, Khalid S, Mullen C, Remes PM, Huguet R, McAlister G, et al. Combining native and 'omics' mass spectrometry to identify endogenous ligands bound to membrane proteins. Nature Methods. 17: 505-508. PMID 32371966 DOI: 10.1038/S41592-020-0821-0  0.657
2020 Urner LH, Liko I, Yen HY, Hoi KK, Bolla JR, Gault J, Almeida FG, Schweder MP, Shutin D, Ehrmann S, Haag R, Robinson CV, Pagel K. Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors. Nature Communications. 11: 564. PMID 31992701 DOI: 10.1038/S41467-020-14424-8  0.677
2020 Pye VE, Rosa A, Bertelli C, Struwe WB, Maslen SL, Corey R, Liko I, Hassall M, Mattiuzzo G, Ballandras-Colas A, Nans A, Takeuchi Y, Stansfeld PJ, Skehel JM, Robinson CV, et al. A bipartite structural organization defines the SERINC family of HIV-1 restriction factors. Nature Structural & Molecular Biology. PMID 31907454 DOI: 10.1038/S41594-019-0357-0  0.467
2020 Urner LH, Schulze M, Maier YB, Hoffmann W, Warnke S, Liko I, Folmert K, Manz C, Robinson CV, Haag R, Pagel K. A new azobenzene-based design strategy for detergents in membrane protein research Chemical Science. 11: 3538-3546. DOI: 10.1039/D0Sc01022G  0.584
2020 Quetschlich D, Agasid MT, Davis RA, Sands ZA, Liko I, Sansom MS, Stansfeld PJ, Robinson CV. Investigating Protein-Lipid Interactions of MthK and Native Bacterial Membrane Lipids Biophysical Journal. 118: 554a. DOI: 10.1016/J.Bpj.2019.11.3031  0.609
2018 Yen HY, Hoi KK, Liko I, Hedger G, Horrell MR, Song W, Wu D, Heine P, Warne T, Lee Y, Carpenter B, Plückthun A, Tate CG, Sansom MSP, Robinson CV. PtdIns(4,5)P stabilizes active states of GPCRs and enhances selectivity of G-protein coupling. Nature. PMID 29995853 DOI: 10.1038/S41586-018-0325-6  0.554
2018 Liko I, Degiacomi MT, Lee S, Newport TD, Gault J, Reading E, Hopper JTS, Housden NG, White P, Colledge M, Sula A, Wallace BA, Kleanthous C, Stansfeld PJ, Bayley H, et al. Lipid binding attenuates channel closure of the outer membrane protein OmpF. Proceedings of the National Academy of Sciences of the United States of America. PMID 29891712 DOI: 10.1073/Pnas.1721152115  0.625
2018 Gupta K, Li J, Liko I, Gault J, Bechara C, Wu D, Hopper JTS, Giles K, Benesch JLP, Robinson CV. Identifying key membrane protein lipid interactions using mass spectrometry. Nature Protocols. 13: 1106-1120. PMID 29700483 DOI: 10.1038/Nprot.2018.014  0.682
2017 Yen HY, Hopper JTS, Liko I, Allison TM, Zhu Y, Wang D, Stegmann M, Mohammed S, Wu B, Robinson CV. Ligand binding to a G protein-coupled receptor captured in a mass spectrometer. Science Advances. 3: e1701016. PMID 28630934 DOI: 10.1126/Sciadv.1701016  0.603
2017 Landreh M, Marklund EG, Uzdavinys P, Degiacomi MT, Coincon M, Gault J, Gupta K, Liko I, Benesch JL, Drew D, Robinson CV. Integrating mass spectrometry with MD simulations reveals the role of lipids in Na(+)/H(+) antiporters. Nature Communications. 8: 13993. PMID 28071645 DOI: 10.1038/Ncomms13993  0.615
2017 Hedger G, Yen H, Liko I, Robinson CV, Siebold C, Sansom MS. Molecular Dynamics Simulations of G-Protein Coupled Receptor Lipid Interactions Biophysical Journal. 112: 386a. DOI: 10.1016/J.Bpj.2016.11.2097  0.565
2016 Liko I, Allison TM, Hopper JT, Robinson CV. Mass spectrometry guided structural biology. Current Opinion in Structural Biology. 40: 136-144. PMID 27721169 DOI: 10.1016/J.Sbi.2016.09.008  0.564
2016 Liko I, Degiacomi MT, Mohammed S, Yoshikawa S, Schmidt C, Robinson CV. Dimer interface of bovine cytochrome c oxidase is influenced by local posttranslational modifications and lipid binding. Proceedings of the National Academy of Sciences of the United States of America. PMID 27364008 DOI: 10.1073/Pnas.1600354113  0.625
2016 Mikhailov VA, Liko I, Mize TH, Bush MF, Benesch JL, Robinson CV. Infrared Laser Activation of Soluble and Membrane Protein Assemblies in the Gas Phase. Analytical Chemistry. PMID 27328020 DOI: 10.1021/Acs.Analchem.6B00645  0.692
2016 Podobnik M, Savory P, Rojko N, Kisovec M, Wood N, Hambley R, Pugh J, Wallace EJ, McNeill L, Bruce M, Liko I, Allison TM, Mehmood S, Yilmaz N, Kobayashi T, et al. Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly. Nature Communications. 7: 11598. PMID 27176125 DOI: 10.1038/Ncomms11598  0.442
2016 Liko I, Hopper JT, Allison TM, Benesch JL, Robinson CV. Negative Ions Enhance Survival of Membrane Protein Complexes. Journal of the American Society For Mass Spectrometry. PMID 27106602 DOI: 10.1007/S13361-016-1381-5  0.644
2016 Gault J, Donlan JA, Liko I, Hopper JT, Gupta K, Housden NG, Struwe WB, Marty MT, Mize T, Bechara C, Zhu Y, Wu B, Kleanthous C, Belov M, Damoc E, et al. High-resolution mass spectrometry of small molecules bound to membrane proteins. Nature Methods. PMID 26901650 DOI: 10.1038/Nmeth.3771  0.668
2015 Allison TM, Reading E, Liko I, Baldwin AJ, Laganowsky A, Robinson CV. Quantifying the stabilizing effects of protein-ligand interactions in the gas phase. Nature Communications. 6: 8551. PMID 26440106 DOI: 10.1038/Ncomms9551  0.658
2015 Landreh M, Liko I, Uzdavinys P, Coincon M, Hopper JT, Drew D, Robinson CV. Controlling release, unfolding and dissociation of membrane protein complexes in the gas phase through collisional cooling. Chemical Communications (Cambridge, England). 51: 15582-4. PMID 26356172 DOI: 10.1039/C5Cc07045G  0.656
2015 Reading E, Walton TA, Liko I, Marty MT, Laganowsky A, Rees DC, Robinson CV. The Effect of Detergent, Temperature, and Lipid on the Oligomeric State of MscL Constructs: Insights from Mass Spectrometry. Chemistry & Biology. 22: 593-603. PMID 26000747 DOI: 10.1016/J.Chembiol.2015.04.016  0.64
2015 Reading E, Liko I, Allison TM, Benesch JL, Laganowsky A, Robinson CV. The role of the detergent micelle in preserving the structure of membrane proteins in the gas phase. Angewandte Chemie (International Ed. in English). 54: 4577-81. PMID 25693501 DOI: 10.1002/Anie.201411622  0.676
2014 Mehmood S, Marcoux J, Hopper JT, Allison TM, Liko I, Borysik AJ, Robinson CV. Charge reduction stabilizes intact membrane protein complexes for mass spectrometry. Journal of the American Chemical Society. 136: 17010-2. PMID 25402655 DOI: 10.1021/Ja510283G  0.696
2014 Zhou M, Politis A, Davies RB, Liko I, Wu KJ, Stewart AG, Stock D, Robinson CV. Ion mobility-mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility. Nature Chemistry. 6: 208-15. PMID 24557135 DOI: 10.1038/Nchem.1868  0.545
2013 Hopper JT, Yu YT, Li D, Raymond A, Bostock M, Liko I, Mikhailov V, Laganowsky A, Benesch JL, Caffrey M, Nietlispach D, Robinson CV. Detergent-free mass spectrometry of membrane protein complexes. Nature Methods. 10: 1206-8. PMID 24122040 DOI: 10.1038/Nmeth.2691  0.682
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