Alexey Glukhov - Publications

Affiliations: 
2012-2015 University of Wisconsin Madison Medical School, Madison, WI, United States 

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Medvedev RY, Afolabi SO, Turner DGP, Glukhov AV. Mechanisms of stretch-induced electro-anatomical remodeling and atrial arrhythmogenesis. Journal of Molecular and Cellular Cardiology. PMID 38797242 DOI: 10.1016/j.yjmcc.2024.05.011  0.807
2024 Lang D, Ni H, Medvedev RY, Liu F, Alvarez-Baron CP, Tyan L, Turner DGP, Warden A, Morotti S, Schrauth TA, Rickert C, Proenza C, Chanda B, Kamp TJ, Robertson GA, ... ... Glukhov AV, et al. Caveolar Compartmentalization is Required for Stable Rhythmicity of Sinus Nodal Cells and is Disrupted in Heart Failure. Biorxiv : the Preprint Server For Biology. PMID 38659841 DOI: 10.1101/2024.04.14.589457  0.816
2023 Glukhov AV, Gorelik J. Mind the Gap: Does Junctophilin 2 Gear the Coupled-Clock System in Pacemaker Cardiomyocytes? Jacc. Basic to Translational Science. 8: 1589-1591. PMID 38205355 DOI: 10.1016/j.jacbts.2023.09.015  0.654
2023 Turner DGP, De Lange WJ, Zhu Y, Coe CL, Simcox J, Ge Y, Kamp TJ, Ralphe JC, Glukhov AV. Neutral sphingomyelinase regulates mechanotransduction in human engineered cardiac tissues and mouse hearts. The Journal of Physiology. PMID 37889115 DOI: 10.1113/JP284807  0.313
2023 Medvedev RY, Turner DGP, DeGuire FC, Leonov V, Lang D, Gorelik J, Alvarado FJ, Bondarenko VE, Glukhov AV. Caveolae-associated cAMP/Ca-mediated mechano-chemical signal transduction in mouse atrial myocytes. Journal of Molecular and Cellular Cardiology. 184: 75-87. PMID 37805125 DOI: 10.1016/j.yjmcc.2023.10.004  0.815
2022 Ding Y, Lang D, Yan J, Bu H, Li H, Jiao K, Yang J, Ni H, Morotti S, Le T, Clark KJ, Port J, Ekker SC, Cao H, Zhang Y, ... ... Glukhov AV, et al. A phenotype-based forward genetic screen identifies as a sick sinus syndrome gene. Elife. 11. PMID 36255053 DOI: 10.7554/eLife.77327  0.673
2022 Turner DGP, Tyan L, DeGuire FC, Medvedev RY, Stroebel SJ, Lang D, Glukhov AV. Caveolin-3 prevents swelling-induced membrane damage via regulation of I activity. Biophysical Journal. PMID 35378081 DOI: 10.1016/j.bpj.2022.04.001  0.781
2021 Lang D, Medvedev RY, Ratajczyk L, Zheng J, Yuan X, Lim E, Han OY, Valdivia HH, Glukhov AV. Region-specific distribution of transversal-axial tubule system organization underlies heterogeneity of calcium dynamics in the right atrium. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34951544 DOI: 10.1152/ajpheart.00381.2021  0.804
2021 Turner D, Kang C, Mesirca P, Hong J, Mangoni ME, Glukhov AV, Sah R. Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity. Frontiers in Cardiovascular Medicine. 8: 662410. PMID 34434970 DOI: 10.3389/fcvm.2021.662410  0.364
2021 Morotti S, Ni H, Peters CH, Rickert C, Asgari-Targhi A, Sato D, Glukhov AV, Proenza C, Grandi E. Intracellular Na Modulates Pacemaking Activity in Murine Sinoatrial Node Myocytes: An Analysis. International Journal of Molecular Sciences. 22. PMID 34073281 DOI: 10.3390/ijms22115645  0.329
2021 Lang D, Glukhov AV. Cellular and Molecular Mechanisms of Functional Hierarchy of Pacemaker Clusters in the Sinoatrial Node: New Insights into Sick Sinus Syndrome. Journal of Cardiovascular Development and Disease. 8. PMID 33924321 DOI: 10.3390/jcdd8040043  0.714
2021 Medvedev RY, Sanchez-Alonso JL, Mansfield CA, Judina A, Francis AJ, Pagiatakis C, Trayanova N, Glukhov AV, Miragoli M, Faggian G, Gorelik J. Local hyperactivation of L-type Ca channels increases spontaneous Ca release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats. Scientific Reports. 11: 4840. PMID 33649357 DOI: 10.1038/s41598-021-84275-w  0.807
2021 de Lange WJ, Farrell ET, Kreitzer CR, Jacobs DR, Lang D, Glukhov AV, Ralphe JC. HUMAN iPSC ENGINEERED CARDIAC TISSUE PLATFORM FAITHFULLY MODELS IMPORTANT CARDIAC PHYSIOLOGY. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33606581 DOI: 10.1152/ajpheart.00941.2020  0.687
2021 Tyan L, Turner D, Komp KR, Medvedev RY, Lim E, Glukhov AV. Caveolin-3 is required for regulation of transient outward potassium current by angiotensin II in mouse atrial myocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33416459 DOI: 10.1152/ajpheart.00569.2020  0.807
2020 Reilly L, Alvarado FJ, Lang D, Abozeid S, Van Ert H, Spellman C, Warden J, Makielski JC, Glukhov AV, Eckhardt LL. Genetic Loss of Causes Adrenergic-Induced Phase 3 Early Afterdepolariz ations and Polymorphic and Bidirectional Ventricular Tachycardia. Circulation. Arrhythmia and Electrophysiology. 13: e008638. PMID 32931337 DOI: 10.1161/Circep.120.008638  0.677
2020 Lang D, Calaghan SC, Gorelik J, Glukhov AV. Editorial: Cardiomyocyte Microdomains: An Emerging Concept of Local Regulation and Remodeling. Frontiers in Physiology. 11: 512. PMID 32574239 DOI: 10.3389/Fphys.2020.00512  0.78
2020 Asfaw TN, Tyan L, Glukhov A, Bondarenko VE. A Compartmentalized Mathematical Model of Mouse Atrial Myocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31951471 DOI: 10.1152/Ajpheart.00460.2019  0.356
2020 Lang D, ratajczyk L, Tyan L, Turner D, Alvarado F, Kamp TJ, Glukhov A. Abstract 418: Caveolar Disruption of L-type Calcium Channel and Ryanodine Receptor Facilitates Atrial Ectopy and Arrhythmogenesis in Heart Failure Mice Circulation Research. 127. DOI: 10.1161/res.127.suppl_1.418  0.407
2020 Medvedev RY, Ratajczyk L, Deguire FC, Vasquez AR, Lang D, Glukhov A. Abstract 376: Functional Significance of Anatomically Heterogeneous Distribution of Transversal-axial Tubule System in Mouse and Human Atrial Myocardium Circulation Research. 127. DOI: 10.1161/res.127.suppl_1.376  0.805
2020 Ratajczyk LN, Irwin AK, Lang D, Glukhov AV. Whole-Atria Optical Analysis of Transverse-Axial Tubule System for Identification of Vulnerable "Hot Spots" for Arrhythmia Development Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.2559  0.595
2020 Yuan X, Ratajczyk LN, Alvarado F, Valdivia HH, Glukhov AV, Lang D. Hierarchical Pacemaker Clustering within the Rabbit Sinoatrial Node is Driven by Dynamic Interaction between the Components of the Coupled-Clock System Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1994  0.583
2019 Alexanian RA, Mahapatra K, Lang D, Vaidyanathan R, Markandeya YS, Gill RK, Zhai AJ, Dhillon A, Lea MR, Abozeid S, Schmuck EG, Raval AN, Eckhardt LL, Glukhov AV, Lalit PA, et al. Induced cardiac progenitor cells repopulate decellularized mouse heart scaffolds and differentiate to generate cardiac tissue. Biochimica Et Biophysica Acta. Molecular Cell Research. 118559. PMID 31634503 DOI: 10.1016/J.Bbamcr.2019.118559  0.711
2019 Egorov YV, Lang D, Tyan L, Turner D, Lim E, Piro ZD, Hernandez JJ, Lodin R, Wang R, Schmuck EG, Raval AN, Ralphe CJ, Kamp TJ, Rosenshtraukh LV, Glukhov AV. Caveolae-Mediated Activation of Mechanosensitive Chloride Channels in Pulmonary Veins Triggers Atrial Arrhythmogenesis. Journal of the American Heart Association. 8: e012748. PMID 31597508 DOI: 10.1161/Jaha.119.012748  0.709
2019 Biermann M, Cai W, Lang D, Hermsen J, Profio L, Zhou Y, Czirok A, Isai DG, Napiwocki BN, Rodriguez AM, Brown ME, Woon MT, Shao A, Han T, Park D, ... ... Glukhov AV, et al. Epigenetic Priming of Human Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation. Stem Cells (Dayton, Ohio). PMID 31087611 DOI: 10.1002/Stem.3021  0.667
2019 Piro ZD, Lodin R, Tyan L, Lim E, Lang D, Glukhov AV. Region-Specific Stretch-Induced Disruption of Caveolae Decreases Expression of Mechanosensitive Chloride Channels and Stimulates Fibrogenesis Promoting Arrhythmogenic Atrial Ectopy in Failing Mice Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2040  0.667
2019 Lang D, Tyan L, Warden A, Piro ZD, Lodin R, Lim E, Irwin A, Glukhov AV. Disruption of Caveolar Microdomains Creates “Hot Spots” for Atrial Ectopy and Arrythmogenesis in Heart Failure Mice Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.1273  0.675
2018 Tyan L, Foell JD, Vincent KP, Woon MT, Mesquitta WT, Lang D, Best JM, Ackerman MJ, McCulloch AD, Glukhov AV, Balijepalli RC, Kamp TJ. Long QT syndrome caveolin-3 mutations differentially modulate K 4 and Ca 1.2 channels to contribute to action potential prolongation. The Journal of Physiology. PMID 30588629 DOI: 10.1113/Jp276014  0.685
2018 Lang D, Glukhov AV. Functional Microdomains in Heart's Pacemaker: A Step Beyond Classical Electrophysiology and Remodeling. Frontiers in Physiology. 9: 1686. PMID 30538641 DOI: 10.3389/Fphys.2018.01686  0.721
2018 Lang D, Egorov YV, Wang R, Rosenshtraukh LV, Glukhov AV. Caveolae-Mediated Activation of Mechanosensitive I CL,SWELL Channels Disrupts Conduction and Promotes Arrhythmogenesis in Pulmonary Veins and Superior Vena Cava Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1722  0.64
2017 Adeyemi O, Alvarez-Laviada A, Schultz F, Ibrahim E, Trauner M, Williamson C, Glukhov AV, Gorelik J. Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis. Plos One. 12: e0183167. PMID 28934223 DOI: 10.1371/Journal.Pone.0183167  0.773
2017 Schobesberger S, Wright P, Tokar S, Bhargava A, Mansfield C, Glukhov AV, Poulet C, Buzuk A, Monszpart A, Sikkel M, Harding SE, Nikolaev VO, Lyon AR, Gorelik J. T-tubule remodelling disturbs localised β2-adrenergic signalling in rat ventricular myocyte during the progression of heart failure. Cardiovascular Research. PMID 28505272 DOI: 10.1093/Cvr/Cvx074  0.763
2017 Lang D, Warden A, Kamp T, Glukhov A. Loss of Caveolin-3 Causes Heart Rhythm Abnormalities by Affecting Ca 2+ -Voltage Coupling in the Mouse Sinoatrial Node Biophysical Journal. 112: 402a. DOI: 10.1016/J.Bpj.2016.11.2180  0.696
2017 Balycheva M, Kamp TJ, Glukhov A. Angiotensin II Stimulates L-Type Calcium Current in Mouse Atrial Myocytes by Affecting Caveolae-Housed Channels Biophysical Journal. 112: 245a. DOI: 10.1016/J.Bpj.2016.11.1340  0.783
2016 Lang D, Glukhov AV. High-resolution Optical Mapping of the Mouse Sino-atrial Node. Journal of Visualized Experiments : Jove. PMID 28060289 DOI: 10.3791/54773  0.701
2016 Sanchez-Alonso JL, Bhargava A, O'Hara T, Glukhov AV, Schobesberger S, Bhogal NK, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J. Microdomain-Specific Modulation of L-type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure. Circulation Research. PMID 27572487 DOI: 10.1161/Circresaha.116.308698  0.81
2016 Holzem KM, Gomez JF, Glukhov AV, Madden EJ, Koppel AC, Ewald GA, Trenor B, Efimov IR. Reduced response to IKr blockade and altered hERG1a/1b stoichiometry in human heart failure. Journal of Molecular and Cellular Cardiology. 96: 82-92. PMID 26093152 DOI: 10.1016/J.Yjmcc.2015.06.008  0.307
2016 Glukhov AV, Balycheva M, Sanchez-Alonso JL, Bhogal N, Diakonov I, Mazzola M, Faggian G, Gorelik J. Microdomain-Specific Remodelling of Autonomic Regulation of L-Type Calcium Channels Revealed by Super-Resolution Scanning Patch Clamp in Rat Atrial Myocytes in Heart Failure Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2416  0.791
2015 Balycheva M, Faggian G, Glukhov AV, Gorelik J. Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling. Biophysical Reviews. 7: 43-62. PMID 28509981 DOI: 10.1007/S12551-014-0159-X  0.815
2015 Glukhov AV, Balycheva M, Sanchez-Alonso JL, Ilkan Z, Alvarez-Laviada A, Bhogal N, Diakonov I, Schobesberger S, Sikkel MB, Bhargava A, Faggian G, Punjabi PP, Houser SR, Gorelik J. Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes. Circulation. 132: 2372-84. PMID 26450916 DOI: 10.1161/Circulationaha.115.018131  0.759
2015 Glukhov AV, Rosenshtraukh LV, Bhargava A, Miragoli M, Boukens BJ. Atrial Fibrillation: Biophysics, Molecular Mechanisms, and Novel Therapies. Biomed Research International. 2015: 780671. PMID 26240827 DOI: 10.1155/2015/780671  0.794
2015 Miragoli M, Glukhov AV. Atrial Fibrillation and Fibrosis: Beyond the Cardiomyocyte Centric View. Biomed Research International. 2015: 798768. PMID 26229964 DOI: 10.1155/2015/798768  0.665
2015 Mazzola M, Diakonov I, Miragoli M, Faggian G, Glukhov AV, Gorelik J. Inhibitory effects of adenosine and adenosine A1 receptors stimulation on catecholamine-induced increase in camp level and force of contraction in atrial and ventricular myocyte Vascular Pharmacology. 75: 62. DOI: 10.1016/J.Vph.2015.11.051  0.773
2014 Lou Q, Hansen BJ, Fedorenko O, Csepe TA, Kalyanasundaram A, Li N, Hage LT, Glukhov AV, Billman GE, Weiss R, Mohler PJ, Györke S, Biesiadecki BJ, Carnes CA, Fedorov VV. Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping. Circulation. 130: 315-24. PMID 24838362 DOI: 10.1161/Circulationaha.113.007086  0.341
2013 Glukhov AV, Uchida K, Efimov IR, Nichols CG. Functional roles of KATP channel subunits in metabolic inhibition. Journal of Molecular and Cellular Cardiology. 62: 90-8. PMID 23624089 DOI: 10.1016/J.Yjmcc.2013.04.016  0.338
2012 Fedorov VV, Glukhov AV, Chang R. Conduction barriers and pathways of the sinoatrial pacemaker complex: their role in normal rhythm and atrial arrhythmias. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1773-83. PMID 22268110 DOI: 10.1152/ajpheart.00892.2011  0.344
2012 Uchida K, Glukhov A, Xia Zhang H, Sulkin M, Laughner J, Kostecki G, Efimov I, Nichols C. Optical Mapping of Cardiac ATP Sensitive Potassium Channel Function under Metabolic Inhibition Biophysical Journal. 102: 339a. DOI: 10.1016/J.Bpj.2011.11.1858  0.418
2011 Lang D, Glukhov AV, Efimova T, Efimov IR. Role of Pyk2 in cardiac arrhythmogenesis. American Journal of Physiology. Heart and Circulatory Physiology. 301: H975-83. PMID 21666110 DOI: 10.1152/Ajpheart.00241.2011  0.734
2011 Fedorov VV, Glukhov AV, Ambrosi CM, Kostecki G, Chang R, Janks D, Schuessler RB, Moazami N, Nichols CG, Efimov IR. Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts. Journal of Molecular and Cellular Cardiology. 51: 215-25. PMID 21586291 DOI: 10.1016/J.Yjmcc.2011.04.016  0.324
2011 Lou Q, Fedorov VV, Glukhov AV, Moazami N, Fast VG, Efimov IR. Transmural heterogeneity and remodeling of ventricular excitation-contraction coupling in human heart failure. Circulation. 123: 1881-90. PMID 21502574 DOI: 10.1161/Circulationaha.110.989707  0.377
2010 Fedorov VV, Chang R, Glukhov AV, Kostecki G, Janks D, Schuessler RB, Efimov IR. Complex interactions between the sinoatrial node and atrium during reentrant arrhythmias in the canine heart. Circulation. 122: 782-9. PMID 20697021 DOI: 10.1161/Circulationaha.109.935288  0.301
2007 Sudharshan S, Fedorov V, Glukhov A, Egorov Y, Rosenshtraukh L, Efimov I. Overexpression of Cx43 and NF200 in the ground squirrel Citellus undulatus heart during the hibernation state The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A487  0.314
2005 Fedorov VV, Li L, Glukhov A, Shishkina I, Aliev RR, Mikheeva T, Nikolski VP, Rosenshtraukh LV, Efimov IR. Hibernator Citellus undulatus maintains safe cardiac conduction and is protected against tachyarrhythmias during extreme hypothermia: possible role of Cx43 and Cx45 up-regulation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 2: 966-75. PMID 16171752 DOI: 10.1016/J.Hrthm.2005.06.012  0.369
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