Edwin Thrower

Affiliations: 
1999-2002 Pharmacology Yale University, New Haven, CT 
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"Edwin Thrower"
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Orabi AI, Luo Y, Ahmad MU, et al. (2012) IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules. Plos One. 7: e48465
Reed AM, Husain SZ, Thrower E, et al. (2011) Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling. The Journal of Biological Chemistry. 286: 1919-26
Gorelick FS, Thrower E. (2009) The acinar cell and early pancreatitis responses. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 7: S10-4
Husain S, Thrower E. (2009) Molecular and cellular regulation of pancreatic acinar cell function. Current Opinion in Gastroenterology. 25: 466-71
Grant W, Shah A, Thrower E, et al. (2006) Caerulein-Induced Intracellular Pancreatic Zymogen Activation Is Dependent Upon Calcineurin Pancreas. 33: 464
Thrower EC, Choe CU, So SH, et al. (2003) A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel. The Journal of Biological Chemistry. 278: 49699-706
Leite MF, Thrower EC, Echevarria W, et al. (2003) Nuclear and cytosolic calcium are regulated independently. Proceedings of the National Academy of Sciences of the United States of America. 100: 2975-80
Jiang QX, Thrower EC, Chester DW, et al. (2002) Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution. The Embo Journal. 21: 3575-81
Thrower EC, Park HY, So SH, et al. (2002) Activation of the inositol 1,4,5-trisphosphate receptor by the calcium storage protein chromogranin A. The Journal of Biological Chemistry. 277: 15801-6
Koulen P, Thrower EC. (2001) Pharmacological modulation of intracellular Ca(2+) channels at the single-channel level. Molecular Neurobiology. 24: 65-86
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