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Kai Deng - Publications

Affiliations: 
Biomaterials and Biomanufacturing Department Sandia National Laboratories 
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Liu Y, Zhao X, Gan F, Chen X, Deng K, Crowe SA, Hudson GA, Belcher MS, Schmidt M, Astolfi MCT, Kosina SM, Pang B, Shao M, Yin J, Sirirungruang S, et al. Complete biosynthesis of QS-21 in engineered yeast. Nature. PMID 38720067 DOI: 10.1038/s41586-024-07345-9  0.573
2024 Pham LTM, Deng K, Choudhary H, Northen TR, Singer SW, Adams PD, Simmons BA, Sale KL. An Engineered Laccase from Accelerates Lignocellulose Degradation. Biomolecules. 14. PMID 38540744 DOI: 10.3390/biom14030324  0.57
2023 Takasuka T, Kim H, Deng K, Bianchetti CM, Yamashita K, Beebe ET, Bergeman LF, Vander Meulen KA, Deutsch S, Ralph J, Adams PD, Northen TR, Fox BG. Quantitative analysis of The High Yield Hydrolysis of Kelp by Laminarinase and Alginate Lyase. Chembiochem : a European Journal of Chemical Biology. e202300357. PMID 37402642 DOI: 10.1002/cbic.202300357  0.618
2023 Ha NS, Onley JR, Deng K, Andeer P, Bowen BP, Gupta K, Kim PW, Kuch N, Kutschke M, Parker A, Song F, Fox B, Adams PD, de Raad M, Northen TR. A combinatorial droplet microfluidic device integrated with mass spectrometry for enzyme screening. Lab On a Chip. PMID 37401915 DOI: 10.1039/d2lc00980c  0.623
2023 Huang J, Quest A, Cruz-Morales P, Deng K, Pereira JH, Van Cura D, Kakumanu R, Baidoo EEK, Dan Q, Chen Y, Petzold CJ, Northen TR, Adams PD, Clark DS, Balskus EP, et al. Complete integration of carbene-transfer chemistry into biosynthesis. Nature. PMID 37138074 DOI: 10.1038/s41586-023-06027-2  0.56
2023 Englund E, Schmidt M, Nava AA, Lechner A, Deng K, Jocic R, Lin Y, Roberts J, Benites VT, Kakumanu R, Gin JW, Chen Y, Liu Y, Petzold CJ, Baidoo EEK, et al. Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase. Journal of the American Chemical Society. PMID 37057992 DOI: 10.1021/jacs.2c11027  0.581
2023 de Raad M, Koper K, Deng K, Bowen BP, Maeda HA, Northen TR. Mass spectrometry imaging-based assays for aminotransferase activity reveal a broad substrate spectrum for a previously uncharacterized enzyme. The Journal of Biological Chemistry. 299: 102939. PMID 36702250 DOI: 10.1016/j.jbc.2023.102939  0.649
2022 Deng K, Wang X, Ing N, Opgenorth P, de Raad M, Kim J, Simmons BA, Adams PD, Singh AK, Lee TS, Northen TR. Rapid quantification of alcohol production in microorganisms based on nanostructure-initiator mass spectrometry (NIMS). Analytical Biochemistry. 114997. PMID 36435200 DOI: 10.1016/j.ab.2022.114997  0.538
2022 Tom LM, Aulitto M, Wu YW, Deng K, Gao Y, Xiao N, Rodriguez BG, Louime C, Northen TR, Eudes A, Mortimer JC, Adams PD, Scheller HV, Simmons BA, Ceja-Navarro JA, et al. Low-abundance populations distinguish microbiome performance in plant cell wall deconstruction. Microbiome. 10: 183. PMID 36280858 DOI: 10.1186/s40168-022-01377-x  0.505
2021 Ing N, Deng K, Chen Y, Aulitto M, Gin JW, Pham TLM, Petzold CJ, Singer SW, Bowen B, Sale KL, Simmons BA, Singh AK, Adams PD, Northen TR. A multiplexed nanostructure-initiator mass spectrometry (NIMS) assay for simultaneously detecting glycosyl hydrolase and lignin modifying enzyme activities. Scientific Reports. 11: 11803. PMID 34083602 DOI: 10.1038/s41598-021-91181-8  0.655
2021 Pham LTM, Deng K, Northen TR, Singer SW, Adams PD, Simmons BA, Sale KL. Experimental and theoretical insights into the effects of pH on catalysis of bond-cleavage by the lignin peroxidase isozyme H8 from Phanerochaete chrysosporium. Biotechnology For Biofuels. 14: 108. PMID 33926536 DOI: 10.1186/s13068-021-01953-7  0.536
2020 Glasgow EM, Kemna EI, Bingman CA, Ing N, Deng K, Bianchetti CM, Takasuka TE, Northen TR, Fox BG. A structural and kinetic survey of GH5_4 endoglucanases reveals determinants of broad substrate specificity and opportunities for biomass hydrolysis. The Journal of Biological Chemistry. 295: 17752-17769. PMID 33454012 DOI: 10.1074/jbc.RA120.015328  0.643
2019 Doud DFR, Bowers RM, Schulz F, De Raad M, Deng K, Tarver A, Glasgow E, Vander Meulen K, Fox B, Deutsch S, Yoshikuni Y, Northen T, Hedlund BP, Singer SW, Ivanova N, et al. Function-driven single-cell genomics uncovers cellulose-degrading bacteria from the rare biosphere. The Isme Journal. PMID 31754206 DOI: 10.1038/S41396-019-0557-Y  0.509
2019 Opgenorth P, Costello Z, Okada T, Goyal G, Chen Y, Gin J, Benites VT, Raad M, Northen TR, Deng K, Deutsch S, Baidoo EEK, Petzold CJ, Hillson NJ, Garcia Martin H, et al. Lessons from two Design-Build-Test-Learn cycles of dodecanol production in Escherichia coli aided by machine learning. Acs Synthetic Biology. PMID 31072100 DOI: 10.1021/Acssynbio.9B00020  0.491
2018 Deng K, Zeng J, Cheng G, Gao J, Sale KL, Simmons BA, Singh AK, Adams PD, Northen TR. Rapid characterization of the activities of lignin-modifying enzymes based on nanostructure-initiator mass spectrometry (NIMS). Biotechnology For Biofuels. 11: 266. PMID 30275906 DOI: 10.1186/S13068-018-1261-2  0.659
2017 Eudes A, Dutta T, Deng K, Jacquet N, Sinha A, Benites VT, Baidoo EEK, Richel A, Sattler SE, Northen TR, Singh S, Simmons BA, Loqué D. SbCOMT (Bmr12) is involved in the biosynthesis of tricin-lignin in sorghum. Plos One. 12: e0178160. PMID 28594846 DOI: 10.1371/Journal.Pone.0178160  0.511
2017 Walker JA, Pattathil S, Bergeman LF, Beebe ET, Deng K, Mirzai M, Northen TR, Hahn MG, Fox BG. Determination of glycoside hydrolase specificities during hydrolysis of plant cell walls using glycome profiling. Biotechnology For Biofuels. 10: 31. PMID 28184246 DOI: 10.1186/S13068-017-0703-6  0.631
2016 Heinemann J, Deng K, Shih SC, Gao J, Adams PD, Singh AK, Northen TR. On-chip integration of droplet microfluidics and nanostructure-initiator mass spectrometry for enzyme screening. Lab On a Chip. PMID 27957569 DOI: 10.1039/C6Lc01182A  0.67
2016 Hiras J, Wu YW, Deng K, Nicora CD, Aldrich JT, Frey D, Kolinko S, Robinson EW, Jacobs JM, Adams PD, Northen TR, Simmons BA, Singer SW. Comparative Community Proteomics Demonstrates the Unexpected Importance of Actinobacterial Glycoside Hydrolase Family 12 Protein for Crystalline Cellulose Hydrolysis. Mbio. 7. PMID 27555310 DOI: 10.1128/Mbio.01106-16  0.57
2016 Yuzawa S, Deng K, Wang G, Baidoo EE, Northen TR, Adams PD, Katz L, Keasling JD. Comprehensive In Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production. Acs Synthetic Biology. PMID 27548700 DOI: 10.1021/Acssynbio.6B00176  0.535
2016 Pereira JH, Heins RA, Gall DL, McAndrew RP, Deng K, Holland KC, Donohue TJ, Noguera DR, Simmons BA, Sale KL, Ralph J, Adams PD. Structural and Biochemical Characterization of the Early and Late Enzymes in the Lignin β-aryl Ether Cleavage Pathway from Sphingobium sp SYK-6. The Journal of Biological Chemistry. PMID 26940872 DOI: 10.1074/Jbc.M115.700427  0.331
2015 Walker JA, Takasuka TE, Deng K, Bianchetti CM, Udell HS, Prom BM, Kim H, Adams PD, Northen TR, Fox BG. Multifunctional cellulase catalysis targeted by fusion to different carbohydrate-binding modules. Biotechnology For Biofuels. 8: 220. PMID 26697109 DOI: 10.1186/S13068-015-0402-0  0.592
2015 Deng K, Takasuka TE, Bianchetti CM, Bergeman LF, Adams PD, Northen TR, Fox BG. Use of Nanostructure-Initiator Mass Spectrometry to Deduce Selectivity of Reaction in Glycoside Hydrolases. Frontiers in Bioengineering and Biotechnology. 3: 165. PMID 26579511 DOI: 10.3389/Fbioe.2015.00165  0.649
2015 Deng K, Guenther JM, Gao J, Bowen BP, Tran H, Reyes-Ortiz V, Cheng X, Sathitsuksanoh N, Heins R, Takasuka TE, Bergeman LF, Geertz-Hansen H, Deutsch S, Loqué D, Sale KL, et al. Development of a High Throughput Platform for Screening Glycoside Hydrolases Based on Oxime-NIMS. Frontiers in Bioengineering and Biotechnology. 3: 153. PMID 26528471 DOI: 10.3389/Fbioe.2015.00153  0.665
2014 Heins RA, Cheng X, Nath S, Deng K, Bowen BP, Chivian DC, Datta S, Friedland GD, D'Haeseleer P, Wu D, Tran-Gyamfi M, Scullin CS, Singh S, Shi W, Hamilton MG, et al. Phylogenomically guided identification of industrially relevant GH1 β-glucosidases through DNA synthesis and nanostructure-initiator mass spectrometry. Acs Chemical Biology. 9: 2082-91. PMID 24984213 DOI: 10.1021/Cb500244V  0.639
2014 Deng K, Takasuka TE, Heins R, Cheng X, Bergeman LF, Shi J, Aschenbrener R, Deutsch S, Singh S, Sale KL, Simmons BA, Adams PD, Singh AK, Fox BG, Northen TR. Rapid kinetic characterization of glycosyl hydrolases based on oxime derivatization and nanostructure-initiator mass spectrometry (NIMS). Acs Chemical Biology. 9: 1470-9. PMID 24819174 DOI: 10.1021/Cb5000289  0.664
2013 Cheng X, Hiras J, Deng K, Bowen B, Simmons BA, Adams PD, Singer SW, Northen TR. High throughput nanostructure-initiator mass spectrometry screening of microbial growth conditions for maximal β-glucosidase production. Frontiers in Microbiology. 4: 365. PMID 24367356 DOI: 10.3389/Fmicb.2013.00365  0.613
2013 Chandrasekaran A, Deng K, Koh CY, Takasuka T, Bergeman LF, Fox BG, Adams PD, Singh AK. A universal flow cytometry assay for screening carbohydrate-active enzymes using glycan microspheres Chemical Communications. 49: 5441-5443. PMID 23536035 DOI: 10.1039/C3Cc39155H  0.301
2012 Greving M, Cheng X, Reindl W, Bowen B, Deng K, Louie K, Nyman M, Cohen J, Singh A, Simmons B, Adams P, Siuzdak G, Northen T. Acoustic deposition with NIMS as a high-throughput enzyme activity assay. Analytical and Bioanalytical Chemistry. 403: 707-11. PMID 22407334 DOI: 10.1007/S00216-012-5908-8  0.677
2012 Deng K, George KW, Reindl W, Keasling JD, Adams PD, Lee TS, Singh AK, Northen TR. Encoding substrates with mass tags to resolve stereospecific reactions using Nimzyme. Rapid Communications in Mass Spectrometry : Rcm. 26: 611-5. PMID 22328213 DOI: 10.1002/Rcm.6134  0.673
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