| Year |
Citation |
Score |
| 2023 |
Bale S, Yang L, Alirezaei M, Wilson R, Ota T, Doyle ED, Cottrell CA, Guenaga J, Tran K, Li W, Stamatatos L, Nemazee D, Ward AB, Wyatt RT. Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response. Frontiers in Immunology. 14: 1180959. PMID 37283743 DOI: 10.3389/fimmu.2023.1180959 |
0.353 |
|
| 2021 |
Aljedani SS, Liban TJ, Tran K, Phad G, Singh S, Dubrovskaya V, Pushparaj P, Martinez-Murillo P, Rodarte J, Mileant A, Mangala Prasad V, Kinzelman R, O'Dell S, Mascola JR, Lee KK, ... ... Wyatt RT, et al. Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathogens. 17: e1009543. PMID 34559844 DOI: 10.1371/journal.ppat.1009543 |
0.351 |
|
| 2019 |
Parks KR, MacCamy AJ, Trichka J, Gray M, Weidle C, Borst AJ, Khechaduri A, Takushi B, Agrawal P, Guenaga J, Wyatt RT, Coler R, Seaman M, LaBranche C, Montefiori DC, et al. Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization. Cell Reports. 29: 3060-3072.e7. PMID 31801073 DOI: 10.1016/J.Celrep.2019.10.071 |
0.346 |
|
| 2019 |
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vázquez Bernat N, ... ... Wyatt RT, et al. Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity. PMID 31732167 DOI: 10.1016/J.Immuni.2019.10.008 |
0.348 |
|
| 2019 |
Phad GE, Pushparaj P, Tran K, Dubrovskaya V, Àdori M, Martinez-Murillo P, Vázquez Bernat N, Singh S, Dionne G, O'Dell S, Bhullar K, Narang S, Sorini C, Villablanca EJ, Sundling C, ... ... Wyatt RT, et al. Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. The Journal of Experimental Medicine. PMID 31704807 DOI: 10.1084/Jem.20191155 |
0.313 |
|
| 2019 |
Lei L, Yang YR, Tran K, Wang Y, Chiang CI, Ozorowski G, Xiao Y, Ward AB, Wyatt RT, Li Y. The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization. Cell Reports. 27: 586-598.e6. PMID 30970260 DOI: 10.1016/J.Celrep.2019.03.039 |
0.312 |
|
| 2018 |
Cao L, Pauthner M, Andrabi R, Rantalainen K, Berndsen Z, Diedrich JK, Menis S, Sok D, Bastidas R, Park SR, Delahunty CM, He L, Guenaga J, Wyatt RT, Schief WR, et al. Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer. Nature Communications. 9: 3693. PMID 30209313 DOI: 10.1038/s41467-018-06121-4 |
0.343 |
|
| 2018 |
Khan SN, Sok D, Tran K, Movsesyan A, Dubrovskaya V, Burton D, Wyatt RT. Targeting the HIV-1 spike and co-receptor with bi- and trispecific antibodies for single-component broad inhibition of entry. Journal of Virology. PMID 29976677 DOI: 10.1128/JVI.00384-18 |
0.326 |
|
| 2018 |
Bale S, Martiné A, Wilson R, Behrens AJ, Le Fourn V, de Val N, Sharma SK, Tran K, Torres JL, Girod PA, Ward AB, Crispin M, Wyatt RT. Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies. Frontiers in Immunology. 9: 1116. PMID 29881382 DOI: 10.3389/Fimmu.2018.01116 |
0.352 |
|
| 2018 |
Boliar S, Patil S, Shukla BN, Ghobbeh A, Deshpande S, Chen W, Guenaga J, Dimitrov DS, Wyatt RT, Chakrabarti BK. Ligand accessibility to the HIV-1 Env co-receptor binding site can occur prior to CD4 engagement and is independent of viral tier category. Virology. 519: 99-105. PMID 29684630 DOI: 10.1016/j.virol.2018.04.002 |
0.304 |
|
| 2017 |
Soldemo M, Àdori M, Stark JM, Feng Y, Tran K, Wilson R, Yang L, Guenaga J, Wyatt RT, Karlsson Hedestam GB. Glutaraldehyde Cross-linking of HIV-1 Env Trimers Skews the Antibody Subclass Response in Mice. Frontiers in Immunology. 8: 1654. PMID 29230223 DOI: 10.3389/Fimmu.2017.01654 |
0.328 |
|
| 2017 |
Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su CY, Sok D, Khan SN, Garces F, Pritchard LK, Wyatt RT, Ward AB, Crispin M, Wilson IA, et al. Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model. Cell Reports. 21: 222-235. PMID 28978475 DOI: 10.1016/J.Celrep.2017.09.024 |
0.355 |
|
| 2017 |
Dubrovskaya V, Guenaga J, de Val N, Wilson R, Feng Y, Movsesyan A, Karlsson Hedestam GB, Ward AB, Wyatt RT. Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response. Plos Pathogens. 13: e1006614. PMID 28902916 DOI: 10.1371/Journal.Ppat.1006614 |
0.33 |
|
| 2017 |
Wang Y, O'Dell S, Turner HL, Chiang CI, Lei L, Guenaga J, Wilson R, Martinez-Murillo P, Doria-Rose N, Ward AB, Mascola JR, Wyatt RT, Karlsson Hedestam GB, Li Y. HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate. Journal of Virology. PMID 28835491 DOI: 10.1128/Jvi.00910-17 |
0.324 |
|
| 2017 |
Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Wyatt RT, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007 |
0.306 |
|
| 2017 |
Bale S, Goebrecht G, Stano A, Wilson R, Ota T, Tran K, Ingale J, Zwick MB, Wyatt RT. Covalent linkage of HIV-1 trimers to synthetic liposomes elicits improved B cell and antibody responses. Journal of Virology. PMID 28592540 DOI: 10.1128/Jvi.00443-17 |
0.328 |
|
| 2017 |
Martinez-Murillo P, Tran K, Guenaga J, Lindgren G, Àdori M, Feng Y, Phad GE, Vázquez Bernat N, Bale S, Ingale J, Dubrovskaya V, O'Dell S, Pramanik L, Spångberg M, Corcoran M, ... ... Wyatt RT, et al. Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach. Immunity. 46: 804-817.e7. PMID 28514687 DOI: 10.1016/J.Immuni.2017.04.021 |
0.34 |
|
| 2017 |
Cale EM, Gorman J, Radakovich NA, Crooks ET, Osawa K, Tong T, Li J, Nagarajan R, Ozorowski G, Ambrozak DR, Asokan M, Bailer RT, Bennici AK, Chen X, Doria-Rose NA, ... ... Wyatt RT, et al. Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity. 46: 777-791.e10. PMID 28514685 DOI: 10.1016/J.Immuni.2017.04.011 |
0.356 |
|
| 2017 |
Cai H, Orwenyo J, Guenaga J, Giddens J, Toonstra C, Wyatt RT, Wang LX. Synthetic multivalent V3 glycopeptides display enhanced recognition by glycan-dependent HIV-1 broadly neutralizing antibodies. Chemical Communications (Cambridge, England). PMID 28466900 DOI: 10.1039/C7Cc02059G |
0.335 |
|
| 2017 |
Stano A, Leaman DP, Kim AS, Zhang L, Autin L, Ingale J, Gift SK, Truong J, Wyatt RT, Olson AJ, Zwick MB. Dense array of spikes on HIV-1 virion particles. Journal of Virology. PMID 28446665 DOI: 10.1128/Jvi.00415-17 |
0.331 |
|
| 2017 |
Karlsson Hedestam GB, Guenaga J, Corcoran M, Wyatt RT. Evolution of B cell analysis and Env trimer redesign. Immunological Reviews. 275: 183-202. PMID 28133805 DOI: 10.1111/imr.12515 |
0.355 |
|
| 2016 |
Chen Y, Wilson R, O'Dell S, Guenaga J, Feng Y, Tran K, Chiang CI, Arendt HE, DeStefano J, Mascola JR, Wyatt RT, Li Y. An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes. Journal of Immunology (Baltimore, Md. : 1950). 197: 3982-3998. PMID 27815444 DOI: 10.4049/Jimmunol.1601134 |
0.363 |
|
| 2016 |
Longo NS, Sutton MS, Shiakolas AR, Guenaga J, Jarosinski MC, Georgiev IS, McKee K, Bailer RT, Louder MK, O'Dell S, Connors M, Wyatt RT, Mascola JR, Doria-Rose NA. Multiple antibody lineages in one donor target the glycan-V3 supersite of the HIV-1 envelope glycoprotein and display a preference for quaternary binding. Journal of Virology. PMID 27654288 DOI: 10.1128/Jvi.01012-16 |
0.342 |
|
| 2016 |
Feng Y, Tran K, Bale S, Kumar S, Guenaga J, Wilson R, de Val N, Arendt H, DeStefano J, Ward AB, Wyatt RT. Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies. Plos Pathogens. 12: e1005767. PMID 27487086 DOI: 10.1371/Journal.Ppat.1005767 |
0.321 |
|
| 2016 |
Ingale J, Stano A, Guenaga J, Sharma SK, Nemazee D, Zwick MB, Wyatt RT. High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells. Cell Reports. PMID 27210756 DOI: 10.1016/J.Celrep.2016.04.078 |
0.313 |
|
| 2016 |
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Chen Y, Deller MC, Hao Y, ... ... Wyatt RT, et al. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity. PMID 27067056 DOI: 10.1016/J.Immuni.2016.03.006 |
0.338 |
|
| 2016 |
Mason RD, Welles HC, Adams C, Chakrabarti BK, Gorman J, Zhou T, Nguyen R, O'Dell S, Lusvarghi S, Bewley CA, Li H, Shaw GM, Sheng Z, Shapiro L, Wyatt R, et al. Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability. Plos Pathogens. 12: e1005537. PMID 27064278 DOI: 10.1371/Journal.Ppat.1005537 |
0.384 |
|
| 2016 |
Wang Y, Sundling C, Wilson R, O'Dell S, Chen Y, Dai K, Phad GE, Zhu J, Xiao Y, Mascola JR, Karlsson Hedestam GB, Wyatt RT, Li Y. High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence. Journal of Immunology (Baltimore, Md. : 1950). PMID 27001953 DOI: 10.4049/Jimmunol.1502543 |
0.332 |
|
| 2016 |
Dai K, Khan SN, Wang Y, He L, Guenaga J, Ingale J, Sundling C, O'Dell S, McKee K, Phad G, Corcoran M, Wilson R, Mascola JR, Zhu J, Li Y, ... ... Wyatt RT, et al. HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation. Scientific Reports. 6: 20987. PMID 26879974 DOI: 10.1038/srep20987 |
0.37 |
|
| 2015 |
Ingale J, Wyatt RT. Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores. Bio-Protocol. 5. PMID 26855965 |
0.313 |
|
| 2015 |
Ingale J, Wyatt RT. Coupling of HIV-1 gp120-derived Core Protein to Paramagnetic Beads and Adsorption Assays. Bio-Protocol. 5. PMID 26855964 |
0.378 |
|
| 2015 |
Guenaga J, Dubrovskaya V, de Val N, Sharma SK, Carrette B, Ward AB, Wyatt RT. Structure-guided redesign increases the propensity of HIV Env to generate highly stable soluble trimers. Journal of Virology. PMID 26719252 DOI: 10.1128/JVI.02652-15 |
0.306 |
|
| 2015 |
Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J, Stewart-Jones G, Destefano J, O'Dell S, LaBranche C, Robinson JE, ... ... Wyatt RT, et al. Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site. Plos Pathogens. 11: e1004932. PMID 26023780 DOI: 10.1371/Journal.Ppat.1004932 |
0.36 |
|
| 2015 |
Phad GE, Vázquez Bernat N, Feng Y, Ingale J, Martinez Murillo PA, O'Dell S, Li Y, Mascola JR, Sundling C, Wyatt RT, Karlsson Hedestam GB. Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization. Journal of Immunology (Baltimore, Md. : 1950). 194: 5903-14. PMID 25964491 DOI: 10.4049/jimmunol.1500122 |
0.368 |
|
| 2015 |
Sharma SK, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT. Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design. Cell Reports. 11: 539-50. PMID 25892233 DOI: 10.1016/J.Celrep.2015.03.047 |
0.314 |
|
| 2015 |
Martinez P, Sundling C, O'Dell S, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation. Scientific Reports. 5: 8925. PMID 25762407 DOI: 10.1038/srep08925 |
0.31 |
|
| 2015 |
Guenaga J, de Val N, Tran K, Feng Y, Satchwell K, Ward AB, Wyatt RT. Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties. Plos Pathogens. 11: e1004570. PMID 25569572 DOI: 10.1371/journal.ppat.1004570 |
0.302 |
|
| 2014 |
Forsell MN, McKee K, Feng Y, Mascola JR, Wyatt RT. HIV-1 envelope glycoprotein trimer immunogenicity elicited in the presence of human CD4 alters the neutralization profile. Aids Research and Human Retroviruses. 30: 1089-98. PMID 25245278 DOI: 10.1089/AID.2014.0104 |
0.317 |
|
| 2014 |
Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Peña AT, ... ... Wyatt RT, et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature. 515: 138-42. PMID 25186731 DOI: 10.1038/Nature13601 |
0.359 |
|
| 2014 |
Navis M, Tran K, Bale S, Phad GE, Guenaga J, Wilson R, Soldemo M, McKee K, Sundling C, Mascola J, Li Y, Wyatt RT, Karlsson Hedestam GB. HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization. Plos Pathogens. 10: e1004337. PMID 25166308 DOI: 10.1371/Journal.Ppat.1004337 |
0.323 |
|
| 2014 |
Madani N, Princiotto AM, Schön A, LaLonde J, Feng Y, Freire E, Park J, Courter JR, Jones DM, Robinson J, Liao HX, Moody AA, Permar S, Haynes B, Smith AB, ... Wyatt R, et al. CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies Journal of Virology. 88: 6542-6555. PMID 24696475 DOI: 10.1128/Jvi.00540-14 |
0.383 |
|
| 2014 |
Tran K, Poulsen C, Guenaga J, de Val N, de Val Alda N, Wilson R, Sundling C, Li Y, Stanfield RL, Wilson IA, Ward AB, Karlsson Hedestam GB, Wyatt RT. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proceedings of the National Academy of Sciences of the United States of America. 111: E738-47. PMID 24550318 DOI: 10.1073/Pnas.1319512111 |
0.344 |
|
| 2013 |
Feng Y, Forsell MN, Flynn B, Adams W, Loré K, Seder R, Wyatt RT, Karlsson Hedestam GB. Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants. Virology. 446: 56-65. PMID 24074567 DOI: 10.1016/j.virol.2013.07.028 |
0.324 |
|
| 2013 |
Chakrabarti BK, Feng Y, Sharma SK, McKee K, Karlsson Hedestam GB, Labranche CC, Montefiori DC, Mascola JR, Wyatt RT. Robust neutralizing antibodies elicited by HIV-1 JRFL envelope glycoprotein trimers in nonhuman primates. Journal of Virology. 87: 13239-51. PMID 24067980 DOI: 10.1128/JVI.01247-13 |
0.363 |
|
| 2013 |
Forsell MN, Soldemo M, Dosenovic P, Wyatt RT, Karlsson MC, Karlsson Hedestam GB. Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization. Journal of Immunology (Baltimore, Md. : 1950). 191: 44-51. PMID 23740950 DOI: 10.4049/jimmunol.1203087 |
0.306 |
|
| 2012 |
Huang J, Ofek G, Laub L, Louder MK, Doria-Rose NA, Longo NS, Imamichi H, Bailer RT, Chakrabarti B, Sharma SK, Alam SM, Wang T, Yang Y, Zhang B, Migueles SA, ... Wyatt R, et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature. 491: 406-12. PMID 23151583 DOI: 10.1038/nature11544 |
0.368 |
|
| 2012 |
Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, ... ... Wyatt R, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008 |
0.309 |
|
| 2012 |
Ota T, Doyle-Cooper C, Cooper AB, Huber M, Falkowska E, Doores KJ, Hangartner L, Le K, Sok D, Jardine J, Lifson J, Wu X, Mascola JR, Poignard P, Binley JM, ... ... Wyatt RT, et al. Anti-HIV B Cell lines as candidate vaccine biosensors. Journal of Immunology (Baltimore, Md. : 1950). 189: 4816-24. PMID 23066156 DOI: 10.4049/Jimmunol.1202165 |
0.304 |
|
| 2012 |
Li Y, O'Dell S, Wilson R, Wu X, Schmidt SD, Hogerkorp CM, Louder MK, Longo NS, Poulsen C, Guenaga J, Chakrabarti BK, Doria-Rose N, Roederer M, Connors M, Mascola JR, ... Wyatt RT, et al. HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins. Journal of Virology. 86: 11231-41. PMID 22875963 DOI: 10.1128/JVI.01543-12 |
0.356 |
|
| 2012 |
Sundling C, Li Y, Huynh N, Poulsen C, Wilson R, O'Dell S, Feng Y, Mascola JR, Wyatt RT, Karlsson Hedestam GB. High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site. Science Translational Medicine. 4: 142ra96. PMID 22786681 DOI: 10.1126/scitranslmed.3003752 |
0.365 |
|
| 2012 |
Dosenovic P, Soldemo M, Scholz JL, O'Dell S, Grasset EK, Pelletier N, Karlsson MC, Mascola JR, Wyatt RT, Cancro MP, Karlsson Hedestam GB. BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses. Journal of Immunology (Baltimore, Md. : 1950). 188: 6018-26. PMID 22561155 DOI: 10.4049/Jimmunol.1200466 |
0.319 |
|
| 2012 |
Wu X, Wang C, O'Dell S, Li Y, Keele BF, Yang Z, Imamichi H, Doria-Rose N, Hoxie JA, Connors M, Shaw GM, Wyatt RT, Mascola JR. Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site. Journal of Virology. 86: 5844-56. PMID 22419808 DOI: 10.1128/Jvi.07139-11 |
0.353 |
|
| 2012 |
Falkowska E, Ramos A, Feng Y, Zhou T, Moquin S, Walker LM, Wu X, Seaman MS, Wrin T, Kwong PD, Wyatt RT, Mascola JR, Poignard P, Burton DR. PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4. Journal of Virology. 86: 4394-403. PMID 22345481 DOI: 10.1128/JVI.06973-11 |
0.324 |
|
| 2012 |
Feng Y, McKee K, Tran K, O'Dell S, Schmidt SD, Phogat A, Forsell MN, Karlsson Hedestam GB, Mascola JR, Wyatt RT. Biochemically defined HIV-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the CD4-binding site. The Journal of Biological Chemistry. 287: 5673-86. PMID 22167180 DOI: 10.1074/jbc.M111.317776 |
0.373 |
|
| 2011 |
Li Y, O'Dell S, Walker LM, Wu X, Guenaga J, Feng Y, Schmidt SD, McKee K, Louder MK, Ledgerwood JE, Graham BS, Haynes BF, Burton DR, Wyatt RT, Mascola JR. Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01. Journal of Virology. 85: 8954-67. PMID 21715490 DOI: 10.1128/Jvi.00754-11 |
0.344 |
|
| 2011 |
Mörner A, Jansson M, Bunnik EM, Schøller J, Vaughan R, Wang Y, Montefiori DC, Otting N, Bontrop R, Bergmeier LA, Singh M, Wyatt RT, Schuitemaker H, Biberfeld G, Thorstensson R, et al. Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques. Journal of Virology. 85: 6442-52. PMID 21490092 DOI: 10.1128/JVI.00129-11 |
0.333 |
|
| 2011 |
Guenaga J, Dosenovic P, Ofek G, Baker D, Schief WR, Kwong PD, Karlsson Hedestam GB, Wyatt RT. Heterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant. Plos One. 6: e16074. PMID 21297864 DOI: 10.1371/Journal.Pone.0016074 |
0.332 |
|
| 2011 |
Chakrabarti BK, Pancera M, Phogat S, O'Dell S, McKee K, Guenaga J, Robinson J, Mascola J, Wyatt RT. HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies. Aids Research and Human Retroviruses. 27: 877-87. PMID 21158699 DOI: 10.1089/AID.2010.0281 |
0.312 |
|
| 2010 |
Sundling C, Forsell MN, O'Dell S, Feng Y, Chakrabarti B, Rao SS, Loré K, Mascola JR, Wyatt RT, Douagi I, Karlsson Hedestam GB. Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates. The Journal of Experimental Medicine. 207: 2003-17. PMID 20679401 DOI: 10.1084/jem.20100025 |
0.368 |
|
| 2010 |
Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, O'Dell S, Louder MK, Wycuff DL, ... ... Wyatt RT, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science (New York, N.Y.). 329: 856-61. PMID 20616233 DOI: 10.1126/Science.1187659 |
0.373 |
|
| 2010 |
Douagi I, Forsell MN, Sundling C, O'Dell S, Feng Y, Dosenovic P, Li Y, Seder R, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates. Journal of Virology. 84: 1683-95. PMID 19955308 DOI: 10.1128/JVI.01896-09 |
0.307 |
|
| 2010 |
Doria-Rose NA, Klein RM, Daniels MG, O'Dell S, Nason M, Lapedes A, Bhattacharya T, Migueles SA, Wyatt RT, Korber BT, Mascola JR, Connors M. Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables. Journal of Virology. 84: 1631-6. PMID 19923174 DOI: 10.1128/Jvi.01482-09 |
0.302 |
|
| 2009 |
Chen L, Kwon YD, Zhou T, Wu X, O'Dell S, Cavacini L, Hessell AJ, Pancera M, Tang M, Xu L, Yang ZY, Zhang MY, Arthos J, Burton DR, Dimitrov DS, ... ... Wyatt R, et al. Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science (New York, N.Y.). 326: 1123-7. PMID 19965434 DOI: 10.1126/Science.1175868 |
0.373 |
|
| 2009 |
Dosenovic P, Chakrabarti B, Soldemo M, Douagi I, Forsell MN, Li Y, Phogat A, Paulie S, Hoxie J, Wyatt RT, Karlsson Hedestam GB. Selective expansion of HIV-1 envelope glycoprotein-specific B cell subsets recognizing distinct structural elements following immunization. Journal of Immunology (Baltimore, Md. : 1950). 183: 3373-82. PMID 19696434 DOI: 10.4049/Jimmunol.0900407 |
0.316 |
|
| 2009 |
Dey B, Svehla K, Xu L, Wycuff D, Zhou T, Voss G, Phogat A, Chakrabarti BK, Li Y, Shaw G, Kwong PD, Nabel GJ, Mascola JR, Wyatt RT. Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site. Plos Pathogens. 5: e1000445. PMID 19478876 DOI: 10.1371/Journal.Ppat.1000445 |
0.302 |
|
| 2009 |
Scheid JF, Mouquet H, Feldhahn N, Seaman MS, Velinzon K, Pietzsch J, Ott RG, Anthony RM, Zebroski H, Hurley A, Phogat A, Chakrabarti B, Li Y, Connors M, Pereyra F, ... ... Wyatt RT, et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature. 458: 636-40. PMID 19287373 DOI: 10.1038/Nature07930 |
0.362 |
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| 2009 |
Scheid JF, Mouquet H, Feldhahn N, Walker BD, Pereyra F, Cutrell E, Seaman MS, Mascola JR, Wyatt RT, Wardemann H, Nussenzweig MC. A method for identification of HIV gp140 binding memory B cells in human blood. Journal of Immunological Methods. 343: 65-7. PMID 19100741 DOI: 10.1016/J.Jim.2008.11.012 |
0.307 |
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| 2009 |
Mörner A, Douagi I, Forsell MNE, Sundling C, Dosenovic P, O'Dell S, Dey B, Kwong PD, Voss G, Thorstensson R, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Human immunodeficiency virus type 1 Env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein Journal of Virology. 83: 540-551. PMID 19004960 DOI: 10.1128/JVI.01102-08 |
0.313 |
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| 2009 |
Li Y, Svehla K, Louder MK, Wycuff D, Phogat S, Tang M, Migueles SA, Wu X, Phogat A, Shaw GM, Connors M, Hoxie J, Mascola JR, Wyatt R. Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals. Journal of Virology. 83: 1045-59. PMID 19004942 DOI: 10.1128/Jvi.01992-08 |
0.39 |
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| 2009 |
Doria-Rose NA, Klein RM, Manion MM, O'Dell S, Phogat A, Chakrabarti B, Hallahan CW, Migueles SA, Wrammert J, Ahmed R, Nason M, Wyatt RT, Mascola JR, Connors M. Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. Journal of Virology. 83: 188-99. PMID 18922865 DOI: 10.1128/Jvi.01583-08 |
0.357 |
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| 2008 |
Sundling C, Schön K, Mörner A, Forsell MN, Wyatt RT, Thorstensson R, Karlsson Hedestam GB, Lycke NY. CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization. The Journal of General Virology. 89: 2954-64. PMID 19008380 DOI: 10.1099/vir.0.2008/005470-0 |
0.313 |
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| 2008 |
Forsell MN, Dey B, Mörner A, Svehla K, O'dell S, Högerkorp CM, Voss G, Thorstensson R, Shaw GM, Mascola JR, Karlsson Hedestam GB, Wyatt RT. B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4. Plos Pathogens. 4: e1000171. PMID 18833294 DOI: 10.1371/journal.ppat.1000171 |
0.329 |
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| 2008 |
Selvarajah S, Puffer BA, Lee FH, Zhu P, Li Y, Wyatt R, Roux KH, Doms RW, Burton DR. Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140. Aids Research and Human Retroviruses. 24: 301-14. PMID 18284327 DOI: 10.1089/Aid.2007.0158 |
0.304 |
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| 2007 |
Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science (New York, N.Y.). 317: 1930-4. PMID 17901336 DOI: 10.1126/Science.1145373 |
0.341 |
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| 2007 |
Li Y, Migueles SA, Welcher B, Svehla K, Phogat A, Louder MK, Wu X, Shaw GM, Connors M, Wyatt RT, Mascola JR. Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nature Medicine. 13: 1032-4. PMID 17721546 DOI: 10.1038/nm1624 |
0.331 |
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| 2007 |
Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, Yang X, Zhang MY, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, Nabel GJ, et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature. 445: 732-7. PMID 17301785 DOI: 10.1038/Nature05580 |
0.351 |
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| 2006 |
Bower JF, Li Y, Wyatt R, Ross TM. HIV-1 Envgp140 trimers elicit neutralizing antibodies without efficient induction of conformational antibodies. Vaccine. 24: 5442-51. PMID 16621193 DOI: 10.1016/J.Vaccine.2006.03.063 |
0.37 |
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| 2005 |
Huang CC, Tang M, Zhang MY, Majeed S, Montabana E, Stanfield RL, Dimitrov DS, Korber B, Sodroski J, Wilson IA, Wyatt R, Kwong PD. Structural biology: Structure of a V3-containing HIV-1 gp120 core Science. 310: 1025-1028. PMID 16284180 DOI: 10.1126/Science.1118398 |
0.333 |
|
| 2005 |
Forsell MN, Li Y, Sundbäck M, Svehla K, Liljeström P, Mascola JR, Wyatt R, Karlsson Hedestam GB. Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus. Journal of Virology. 79: 10902-14. PMID 16103142 DOI: 10.1128/JVI.79.17.10902-10914.2005 |
0.369 |
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| 2005 |
Pancera M, Wyatt R. Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage. Virology. 332: 145-56. PMID 15661147 DOI: 10.1016/j.virol.2004.10.042 |
0.37 |
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| 2005 |
Grundner C, Li Y, Louder M, Mascola J, Yang X, Sodroski J, Wyatt R. Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins. Virology. 331: 33-46. PMID 15582651 DOI: 10.1016/J.Virol.2004.09.022 |
0.37 |
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| 2004 |
Grundner C, Pancera M, Kang JM, Koch M, Sodroski J, Wyatt R. Factors limiting the immunogenicity of HIV-1 gp120 envelope glycoproteins. Virology. 330: 233-48. PMID 15527849 DOI: 10.1016/J.Virol.2004.08.037 |
0.371 |
|
| 2004 |
Ofek G, Tang M, Sambor A, Katinger H, Mascola JR, Wyatt R, Kwong PD. Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope. Journal of Virology. 78: 10724-37. PMID 15367639 DOI: 10.1128/JVI.78.19.10724-10737.2004 |
0.31 |
|
| 2004 |
Brainard DM, Tharp WG, Granado E, Miller N, Trocha AK, Ren XH, Conrad B, Terwilliger EF, Wyatt R, Walker BD, Poznansky MC. Migration of antigen-specific T cells away from CXCR4-binding human immunodeficiency virus type 1 gp120. Journal of Virology. 78: 5184-93. PMID 15113900 DOI: 10.1128/Jvi.78.10.5184-5193.2004 |
0.339 |
|
| 2004 |
Huang CC, Venturi M, Majeed S, Moore MJ, Phogat S, Zhang MY, Dimitrov DS, Hendrickson WA, Robinson J, Sodroski J, Wyatt R, Choe H, Farzan M, Kwong PD. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proceedings of the National Academy of Sciences of the United States of America. 101: 2706-2711. PMID 14981267 DOI: 10.1073/Pnas.0308527100 |
0.35 |
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| 2003 |
Labrijn AF, Poignard P, Raja A, Zwick MB, Delgado K, Franti M, Binley J, Vivona V, Grundner C, Huang CC, Venturi M, Petropoulos CJ, Wrin T, Dimitrov DS, Robinson J, ... ... Wyatt RT, et al. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1. Journal of Virology. 77: 10557-65. PMID 12970440 DOI: 10.1128/Jvi.77.19.10557-10565.2003 |
0.379 |
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| 2003 |
Koch M, Pancera M, Kwong PD, Kolchinsky P, Grundner C, Wang L, Hendrickson WA, Sodroski J, Wyatt R. Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition Virology. 313: 387-400. PMID 12954207 DOI: 10.1016/S0042-6822(03)00294-0 |
0.368 |
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| 2002 |
Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, Majeed S, Steenbeke TD, Venturi M, Chaiken I, Fung M, Katinger H, Parren PWIH, Robinson J, Van Ryk D, Wang L, ... ... Wyatt R, et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature. 420: 678-682. PMID 12478295 DOI: 10.1038/Nature01188 |
0.325 |
|
| 2002 |
Grundner C, Mirzabekov T, Sodroski J, Wyatt R. Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins. Journal of Virology. 76: 3511-21. PMID 11884575 DOI: 10.1128/Jvi.76.7.3511-3521.2002 |
0.39 |
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