Leonard G Luyt - Publications

Affiliations: 
The University of Western Ontario (Canada) 
Area:
organic chemistry, medicinal chemistry, radiochemistry

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Year Citation  Score
2023 Campaña MB, Davis TR, Novak SX, Cleverdon ER, Bates M, Krishnan N, Curtis ER, Childs MD, Pierce MR, Morales-Rodriguez Y, Sieburg MA, Hehnly H, Luyt LG, Hougland JL. Cellular Uptake of a Fluorescent Ligand Reveals Ghrelin -Acyltransferase Interacts with Extracellular Peptides and Exhibits Unexpected Localization for a Secretory Pathway Enzyme. Acs Chemical Biology. PMID 37494676 DOI: 10.1021/acschembio.3c00334  0.321
2023 Childs MD, Chandrabalan A, Hodgson D, Ramachandran R, Luyt LG. Discovery of Ghrelin(1-8) Analogues with Improved Stability and Functional Activity for PET Imaging. Acs Pharmacology & Translational Science. 6: 1075-1086. PMID 37470019 DOI: 10.1021/acsptsci.3c00088  0.303
2022 Fittipaldi AS, Castrogiovanni D, Lufrano D, Saenz C, De Francesco PN, Lalonde T, Luyt LG, Cantel S, Fehrentz JA, Andreoli MF, Perello M. Ghrelin proteolysis increases in plasma of men, but not women, with obesity. Life Sciences. 313: 121305. PMID 36543283 DOI: 10.1016/j.lfs.2022.121305  0.685
2022 LeSarge JC, Thibeault P, Yu L, Childs MD, Mirka VM, Qi Q, Fox MS, Kovacs MS, Ramachandran R, Luyt LG. Protease-activated receptor 2 (PAR2)-targeting peptide derivatives for positron emission tomography (PET) imaging. European Journal of Medicinal Chemistry. 246: 114989. PMID 36527934 DOI: 10.1016/j.ejmech.2022.114989  0.346
2021 Childs MD, Yu L, Kovacs MS, Luyt LG. Radiofluorination of non-activated aromatic prosthetic groups for synthesis and evaluation of fluorine-18 labelled ghrelin(1-8) analogues. Organic & Biomolecular Chemistry. PMID 34590643 DOI: 10.1039/d1ob01023a  0.309
2021 von Spreckelsen N, Fadzen CM, Hartrampf N, Ghotmi Y, Wolfe JM, Dubey S, Yang BY, Kijewski MF, Wang S, Farquhar C, Bergmann S, Zdioruk M, Wasserburg JR, Scott B, Murrell E, ... ... Luyt LG, et al. Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican. Advanced Therapeutics. 4. PMID 33997269 DOI: 10.1002/adtp.202000244  0.705
2021 Sullivan R, Randhawa VK, Lalonde T, Yu T, Kiaii B, Luyt L, Wisenberg G, Dhanvantari S. Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease. Cjc Open. 3: 182-194. PMID 33644732 DOI: 10.1016/j.cjco.2020.10.015  0.743
2020 Sharma N, Barbon SM, Lalonde T, Maar RR, Milne M, Gilroy JB, Luyt LG. The development of peptide-boron difluoride formazanate conjugates as fluorescence imaging agents. Rsc Advances. 10: 18970-18977. PMID 35518290 DOI: 10.1039/d0ra02104k  0.807
2020 Childs MD, Luyt LG. A Decade's Progress in the Development of Molecular Imaging Agents Targeting the Growth Hormone Secretagogue Receptor. Molecular Imaging. 19: 1536012120952623. PMID 33104445 DOI: 10.1177/1536012120952623  0.312
2020 Hauser-Kawaguchi A, Tolg C, Peart T, Milne M, Turley EA, Luyt LG. Corrigendum to "A truncated RHAMM protein for discovering novel therapeutic peptides" [Bioorg. Med. Chem. 26 (2018) 5194-5203]. Bioorganic & Medicinal Chemistry. 115543. PMID 32423782 DOI: 10.1016/J.Bmc.2020.115543  0.363
2020 Murrell E, Luyt LG. Incorporation of Fluorine into an OBOC Peptide Library by Copper-Free Click Chemistry toward the Discovery of PET Imaging Agents. Acs Combinatorial Science. PMID 32011850 DOI: 10.1021/Acscombsci.9B00146  0.729
2020 Sharma N, Barbon SM, Lalonde T, Maar RR, Milne M, Gilroy JB, Luyt LG. The development of peptide–boron difluoride formazanate conjugates as fluorescence imaging agents Rsc Advances. 10: 18970-18977. DOI: 10.1039/D0Ra02104K  0.799
2019 Thibeault PE, LeSarge JC, Arends D, Fernandes M, Chidiac P, Stathopulos PB, Luyt LG, Ramachandran R. Molecular basis for activation and biased signalling at the thrombin-activated GPCR Proteinase Activated Receptor-4 (PAR4). The Journal of Biological Chemistry. PMID 31892516 DOI: 10.1074/Jbc.Ra119.011461  0.365
2019 Turnbull WL, Murrell E, Bulcan-Gnirss M, Majeed M, Milne M, Luyt LG. A study of Tc/Re-tricarbonyl complexes of 4-amino-1,8-naphthalimides. Dalton Transactions (Cambridge, England : 2003). PMID 31490511 DOI: 10.1039/C9Dt01752F  0.67
2019 Lalonde T, Hou J, Thibeault PE, Milne M, Dhanvantari S, Ramachandran R, Luyt LG. Single Amino Acid Replacement in G-7039 Leads to a 70-Fold Increase in Binding Towards GHS-R1a. Chemmedchem. PMID 31469937 DOI: 10.1002/Cmdc.201900466  0.767
2019 LeSarge JC, Thibeault P, Milne M, Ramachandran R, Luyt LG. High Affinity Fluorescent Probe for Proteinase-Activated Receptor 2 (PAR2). Acs Medicinal Chemistry Letters. 10: 1045-1050. PMID 31312406 DOI: 10.1021/Acsmedchemlett.9B00094  0.444
2019 Sullivan R, Randhawa VK, Stokes A, Wu D, Lalonde T, Kiaii B, Luyt L, Wisenberg G, Dhanvantari S. Dynamics of the Ghrelin/Growth Hormone Secretagogue Receptor System in the Human Heart Before and After Cardiac Transplantation. Journal of the Endocrine Society. 3: 748-762. PMID 30937420 DOI: 10.1210/Js.2018-00393  0.748
2019 Yu L, Despotovic N, Kovacs MS, Pin CL, Luyt LG. F-Labeled PET Probe Targeting Enhancer of Zeste Homologue 2 (EZH2) for Cancer Imaging. Acs Medicinal Chemistry Letters. 10: 334-340. PMID 30891136 DOI: 10.1021/Acsmedchemlett.8B00613  0.351
2019 von Spreckelsen N, Ghotmi Y, Fadzen C, Wolfe J, Hartrampf N, Bergmann S, Qu Y, Murrell E, Bononi F, Luyt L, Lamfers M, Ligon K, Chiocca E, Viapiano M, Pentelute BL, et al. DDIS-36. BTP-7, A NOVEL PEPTIDE FOR THERAPEUTIC TARGETING OF MALIGNANT BRAIN TUMORS Neuro-Oncology. 21: vi71-vi71. DOI: 10.1093/neuonc/noz175.287  0.671
2019 Murrell E, Turnbull W, Bulcan-Gnirss M, Luyt L. Dual modal fluorescence/SPECT imaging probes: 4-Amino-1,8-naphthalimide 99mTc/Re-tricarbonyl complexes Nuclear Medicine and Biology. DOI: 10.1016/S0969-8051(19)30197-0  0.356
2019 Sullivan R, Randhawa V, Lalonde T, Luyt L, Wisenberg G, Dhanvantari S. THE GROWTH HORMONE SECRETAGOGUE RECEPTOR, GHRELIN, AND BNP IN HUMAN HEART DISEASE WITH PRESERVED EJECTION FRACTION Canadian Journal of Cardiology. 35: S112-S113. DOI: 10.1016/J.Cjca.2019.07.510  0.734
2019 Lalonde T, Fowkes MM, Hou J, Thibeault PE, Milne M, Dhanvantari S, Ramachandran R, Luyt LG. Front Cover: Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a (ChemMedChem 20/2019) Chemmedchem. 14: 1743-1743. DOI: 10.1002/Cmdc.201900563  0.743
2018 Turnbull WL, Yu L, Murrell E, Milne M, Charron CL, Luyt LG. A dual modality Tc/Re(i)-labelled T140 analogue for imaging of CXCR4 expression. Organic & Biomolecular Chemistry. PMID 30574973 DOI: 10.1039/C8Ob01947A  0.805
2018 Luyt LG. The Chimera That Curbs Appetite. Journal of Medicinal Chemistry. PMID 30507118 DOI: 10.1021/Acs.Jmedchem.8B01809  0.314
2018 Charron CL, McFarland MS, Dhanvantari S, Luyt LG. Development of a [Ga]-ghrelin analogue for PET imaging of the ghrelin receptor (GHS-R1a). Medchemcomm. 9: 1761-1767. PMID 30429981 DOI: 10.1039/C8Md00210J  0.811
2018 Abbas A, Yu L, Lalonde T, Wu D, Thiessen JD, Luyt LG, Dhanvantari S. Development and Characterization of an F-labeled Ghrelin Peptidomimetic for Imaging the Cardiac Growth Hormone Secretagogue Receptor. Molecular Imaging. 17: 1536012118809587. PMID 30394854 DOI: 10.1177/1536012118809587  0.769
2018 Fowkes MM, Lalonde T, Yu L, Dhanvantari S, Kovacs MS, Luyt LG. Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor. European Journal of Medicinal Chemistry. 157: 1500-1511. PMID 30282322 DOI: 10.1016/J.Ejmech.2018.08.062  0.788
2018 Uriarte M, De Francesco PN, Fernandez G, Cabral A, Castrogiovanni D, Lalonde T, Luyt LG, Trejo S, Perello M. Evidence Supporting a Role for the Blood-Cerebrospinal Fluid Barrier Transporting Circulating Ghrelin into the Brain. Molecular Neurobiology. PMID 30276663 DOI: 10.1007/S12035-018-1362-8  0.722
2018 Hauser-Kawaguchi A, Tolg C, Peart T, Milne M, Turley EA, Luyt LG. A truncated RHAMM protein for discovering novel therapeutic peptides. Bioorganic & Medicinal Chemistry. PMID 30249497 DOI: 10.1016/J.Bmc.2018.09.018  0.389
2018 Turnbull WL, Luyt LG. Amino-Substituted 2,2'-Bipyridine Ligands as Fluorescent Indicators for Zn(II) and Applications for Fluorescence Imaging of Prostate Cells. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30051526 DOI: 10.1002/Chem.201803051  0.315
2018 Murrell E, Kovacs MS, Luyt LG. A Compact and Synthetically Accessible Fluorine-18 Labelled Cyclooctyne Prosthetic Group for Labelling of Biomolecules by Copper-free Click Chemistry. Chemmedchem. PMID 29923326 DOI: 10.1002/Cmdc.201800334  0.722
2018 Sullivan R, McGirr R, Hu S, Tan A, Wu D, Charron C, Lalonde T, Arany E, Chakrabarti S, Luyt L, Dhanvantari S. Changes in the Cardiac GHSR1a-Ghrelin System Correlate With Myocardial Dysfunction in Diabetic Cardiomyopathy in Mice. Journal of the Endocrine Society. 2: 178-189. PMID 29450407 DOI: 10.1210/Js.2017-00433  0.76
2018 Hauser-Kawaguchi A, Luyt LG, Turley E. Design of peptide mimetics to block pro-inflammatory functions of HA fragments. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29408009 DOI: 10.1016/J.Matbio.2018.01.021  0.326
2018 Hou JQ, Kovacs MS, Dhanvantari S, Luyt LG. Development of Candidates for PET Imaging of Ghrelin Receptor in Disease: Design, Synthesis and Evaluation of Fluorine-bearing Quinazolinone Derivatives. Journal of Medicinal Chemistry. PMID 29327929 DOI: 10.1021/Acs.Jmedchem.7B01754  0.421
2018 Cho C, Ghotmi Y, Fadzan C, Wolfe J, Bergmann S, Qu Y, Murrell E, Bononi F, Luyt L, Chiocca EA, Viapiano M, Pentelute B, Lawler S. DDIS-26. BTP-7, A NOVEL PEPTIDE FOR THERAPEUTIC TARGETING OF MALIGNANT BRAIN TUMORS Neuro-Oncology. 20: vi74-vi74. DOI: 10.1093/Neuonc/Noz175.287  0.692
2018 Long W, Lu Y, Zhang K, Huang X, Hou J, Cai S, Li Y, Du X, Luyt LG, Wong W, Chow C. Boosting the turn-on fluorescent signaling ability of thiazole orange dyes: The effectiveness of structural modification site and its unusual interaction behavior with nucleic acids Dyes and Pigments. 159: 449-456. DOI: 10.1016/J.Dyepig.2018.07.008  0.328
2018 Naghibosadat M, Lalonde T, Luyt L, Hoffman L, Dhanvantari S. GHRELIN AND DES-ACYL GHRELIN BINDING IN CARDIAC TISSUE ARE ALTERED WITH CARDIOVASCULAR INFLAMMATION IN DUCHENNE MUSCULAR DYSTROPHY Canadian Journal of Cardiology. 34: S33. DOI: 10.1016/J.CJCA.2018.07.361  0.718
2018 Lalonde T, Shepherd TG, Dhanvantari S, Luyt LG. Stapled ghrelin peptides as fluorescent imaging probes Peptide Science. 111: e24055. DOI: 10.1002/Pep2.24055  0.774
2017 Cho CF, Yu L, Nsiama TK, Kadam AN, Raturi A, Shukla S, Amadei GA, Steinmetz NF, Luyt LG, Lewis JD. Viral nanoparticles decorated with novel EGFL7 ligands enable intravital imaging of tumor neovasculature. Nanoscale. PMID 28799610 DOI: 10.1039/C7Nr02558K  0.415
2017 Charron CL, Hou JQ, McFarland MS, Dhanvantari S, Kovacs MS, Luyt LG. Structure-Activity Study of Ghrelin(1-8) Resulting in High Affinity Fluorine-bearing Ligands for the Ghrelin Receptor. Journal of Medicinal Chemistry. PMID 28719746 DOI: 10.1021/Acs.Jmedchem.7B00164  0.817
2017 Bahrami SB, Tolg C, Peart T, Symonette C, Veiseh M, Umoh JU, Holdsworth DW, McCarthy JB, Luyt LG, Bissell MJ, Yazdani A, Turley EA. Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 28217782 DOI: 10.1039/C7Ib00002B  0.373
2017 Charron CL, Hickey JL, Nsiama TK, Cruickshank DR, Turnbull WL, Luyt LG. Molecular imaging probes derived from natural peptides. Natural Product Reports. 33: 761-800. PMID 26911790 DOI: 10.1039/C5Np00083A  0.8
2017 Cho C, Ghotmi Y, Fazden C, Wolfe J, Bononi F, Murrell E, Luyt L, Viapiano M, Pentelute B, Chiocca EA, Lawler SE. DDIS-19. NOVEL PEPTIDE HOMING TO GLIOMA-SPECIFIC ISOFORM OF BREVICAN SELECTIVELY TARGETS MALIGNANT BRAIN TUMORS Neuro-Oncology. 19: vi62-vi63. DOI: 10.1093/Neuonc/Nox168.254  0.686
2017 Barbon SM, Novoa S, Bender D, Groom H, Luyt LG, Gilroy JB. Copper-assisted azide–alkyne cycloaddition chemistry as a tool for the production of emissive boron difluoride 3-cyanoformazanates Organic Chemistry Frontiers. 4: 178-190. DOI: 10.1039/C6Qo00640J  0.31
2017 Sun N, Wang C, Xu M, Lu Y, Zheng Y, Yan Y, Guo X, Hou J, Zhang K, Luyt LG, Wong W, Chow C. The interaction of a structural flexible small molecule with nucleic acid structures: Investigation of the origin of fluorescence signal discrimination in sensing and the utilization in live cell imaging Sensors and Actuators B: Chemical. 250: 543-551. DOI: 10.1016/J.Snb.2017.05.018  0.316
2017 Sullivan R, Randhawa V, Stokes A, Liu S, Wu D, Charron C, Lalonde T, Luyt L, Kiaii B, Wisenberg G, Dhanvantari S. EXPRESSION OF THE GROWTH HORMONE SECRETAGOGUE RECEPTOR AND GHRELIN IN HUMAN HEART FAILURE Canadian Journal of Cardiology. 33: S205-S206. DOI: 10.1016/J.Cjca.2017.07.403  0.763
2017 Simpson EJ, Gobbo P, Bononi FC, Murrell E, Workentin MS, Luyt LG. Bombesin-functionalized water-soluble gold nanoparticles for targeting prostate cancer Journal of Interdisciplinary Nanomedicine. 2: 174-187. DOI: 10.1002/jin2.33  0.747
2016 Hou J, Charron CL, Fowkes MM, Luyt LG. Bridging computational modeling with amino acid replacements to investigate GHS-R1a-peptidomimetic recognition. European Journal of Medicinal Chemistry. 123: 822-833. PMID 27541265 DOI: 10.1016/J.Ejmech.2016.07.078  0.77
2016 Lu YJ, Deng Q, Hou JQ, Hu DP, Wang ZY, Zhang K, Luyt LG, Wong WL, Chow CF. Molecular Engineering of Thiazole Orange Dye: Change of Fluorescent Signaling from Universal to Specific upon Binding with Nucleic Acids in Bioassay. Acs Chemical Biology. PMID 26752011 DOI: 10.1021/Acschembio.5B00987  0.318
2016 Cho C, Kasai K, Wolfe J, Hornburg K, Bononi F, Luyt L, Pentelute B, Viapiano M, Chiocca EA, Lawler SE. EXTH-51. BREVICAN-SPECIFIC PEPTIDES FOR THE DEVELOPMENT OF NEXT-GENERATION TARGETED THERANOSTICS FOR MALIGNANT GLIOMAS Neuro-Oncology. 18: vi70-vi70. DOI: 10.1093/Neuonc/Now212.293  0.364
2015 Esguerra KV, Tolg C, Akentieva N, Price M, Cho CF, Lewis JD, McCarthy JB, Turley EA, Luyt LG. Identification, design and synthesis of tubulin-derived peptides as novel hyaluronan mimetic ligands for the receptor for hyaluronan-mediated motility (RHAMM/HMMR). Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 26456171 DOI: 10.1039/C5Ib00222B  0.424
2015 Maar RR, Barbon SM, Sharma N, Groom H, Luyt LG, Gilroy JB. Evaluation of Anisole-Substituted Boron Difluoride Formazanate Complexes for Fluorescence Cell Imaging. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26397738 DOI: 10.1002/Chem.201502821  0.487
2015 Behnam Azad B, Rota V, Yu L, McGirr R, St Amant AH, Lee TY, Dhanvantari S, Luyt LG. Synthesis and evaluation of optical and PET GLP-1 peptide analogues for GLP-1R imaging. Molecular Imaging. 14. PMID 25762192 DOI: 10.2310/7290.2014.00057  0.388
2015 Bononi FC, Luyt LG. Synthesis and cell-based screening of one-bead-one-compound peptide libraries. Methods in Molecular Biology (Clifton, N.J.). 1248: 223-37. PMID 25616336 DOI: 10.1007/978-1-4939-2020-4_15  0.367
2015 Hickey JL, Simpson EJ, Hou J, Luyt LG. An integrated imaging probe design: the synthesis of (99m)Tc/Re-containing macrocyclic peptide scaffolds. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 568-78. PMID 25388204 DOI: 10.1002/Chem.201404774  0.798
2015 Cho C, Bononi F, Wolfe J, Pentelute B, Luyt L, Viapiano M, Chiocca EA, Lawler S. ATPS-08DISCOVERY OF NOVEL GLIOMA-TARGETING PEPTIDES USING A HIGH-THROUGHPUT MICROFLUIDIC MAGNETIC-ACTIVATED SORTER Neuro-Oncology. 17: v19.4-v19. DOI: 10.1093/Neuonc/Nov204.08  0.385
2015 Hickey JL, Simpson EJ, Hou J, Luyt LG. Frontispiece: An Integrated Imaging Probe Design: The Synthesis of99mTc/Re-Containing Macrocyclic Peptide Scaffolds Chemistry - a European Journal. 21: n/a-n/a. DOI: 10.1002/Chem.201580262  0.798
2014 Bruckman MA, Jiang K, Simpson EJ, Randolph LN, Luyt LG, Yu X, Steinmetz NF. Dual-modal magnetic resonance and fluorescence imaging of atherosclerotic plaques in vivo using VCAM-1 targeted tobacco mosaic virus. Nano Letters. 14: 1551-8. PMID 24499194 DOI: 10.1021/Nl404816M  0.681
2014 Douglas GA, McGirr R, Charlton CL, Kagan DB, Hoffman LM, Luyt LG, Dhanvantari S. Characterization of a far-red analog of ghrelin for imaging GHS-R in P19-derived cardiomyocytes. Peptides. 54: 81-8. PMID 24468548 DOI: 10.1016/J.Peptides.2014.01.011  0.38
2014 Cho CF, Shukla S, Simpson EJ, Steinmetz NF, Luyt LG, Lewis JD. Molecular targeted viral nanoparticles as tools for imaging cancer. Methods in Molecular Biology (Clifton, N.J.). 1108: 211-30. PMID 24243252 DOI: 10.1007/978-1-62703-751-8_16  0.699
2014 Cho C, Fung LA, Nsiama T, Yu L, Kadam A, Quail DF, Carmine-Simmen K, Pink D, Postovit L, Luyt LG, Lewis JD. Abstract 4812: A novel EGFL7-derived peptide, E7C13, is a potent anti-tumor agent that inhibits angiogenesis in a beta 1 integrin- and thrombospondin-dependent manner Cancer Research. 74: 4812-4812. DOI: 10.1158/1538-7445.Am2014-4812  0.324
2014 Sharma N, Behnam Azad B, Luyt LG. Development of Ga-PpIX peptides as fluorescence/PET imaging probes Nuclear Medicine and Biology. 41: 632. DOI: 10.1016/J.Nucmedbio.2014.05.124  0.561
2013 Cho CF, Behnam Azad B, Luyt LG, Lewis JD. High-throughput screening of one-bead-one-compound peptide libraries using intact cells. Acs Combinatorial Science. 15: 393-400. PMID 23819541 DOI: 10.1021/Co4000584  0.355
2012 Cho CF, Amadei GA, Breadner D, Luyt LG, Lewis JD. Discovery of novel integrin ligands from combinatorial libraries using a multiplex "beads on a bead" approach. Nano Letters. 12: 5957-65. PMID 23094984 DOI: 10.1021/Nl3034043  0.369
2012 Hickey JL, Luyt LG. Synthesis of rhenium-centric reverse turn mimics. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 12999-3007. PMID 22945687 DOI: 10.1002/Chem.201201766  0.735
2012 Simpson EJ, Hickey JL, Breadner D, Luyt LG. Investigation of isomer formation upon coordination of bifunctional histidine analogues with 99mTc/Re(CO)3. Dalton Transactions (Cambridge, England : 2003). 41: 2950-8. PMID 22266949 DOI: 10.1039/C2Dt11962E  0.775
2012 Azad BB, Cho CF, Lewis JD, Luyt LG. Synthesis, radiometal labeling and in vitro evaluation of a targeted PPIX derivative. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 70: 505-11. PMID 22178308 DOI: 10.1016/J.Apradiso.2011.11.054  0.754
2012 Lu C, McFarland MS, Nesbitt RL, Williams AK, Chan S, Gomez-Lemus J, Autran-Gomez AM, Al-Zahrani A, Chin JL, Izawa JI, Luyt LG, Lewis JD. Ghrelin receptor as a novel imaging target for prostatic neoplasms. The Prostate. 72: 825-33. PMID 21919027 DOI: 10.1002/Pros.21484  0.396
2011 McGirr R, McFarland MS, McTavish J, Luyt LG, Dhanvantari S. Design and characterization of a fluorescent ghrelin analog for imaging the growth hormone secretagogue receptor 1a Regulatory Peptides. 172: 69-76. PMID 21893106 DOI: 10.1016/J.Regpep.2011.08.011  0.45
2011 Steinmetz NF, Ablack AL, Hickey JL, Ablack J, Manocha B, Mymryk JS, Luyt LG, Lewis JD. Intravital imaging of human prostate cancer using viral nanoparticles targeted to gastrin-releasing Peptide receptors. Small (Weinheim An Der Bergstrasse, Germany). 7: 1664-72. PMID 21520408 DOI: 10.1002/Smll.201000435  0.734
2011 Cho C, Amadei G, Breadner D, Luyt L, Lewis J. Abstract 1763: The discovery of novel non-RGD-containing αvβ3 ligands for molecular imaging Cancer Research. 71: 1763-1763. DOI: 10.1158/1538-7445.Am2011-1763  0.393
2011 Lu C, Williams A, Chan S, McFarland M, Gomez-Lemus J, Chin J, Izawa J, Luyt L, Lewis J. 2317 GHRELIN RECEPTOR LABELING AS A NOVEL IMAGING MARKER FOR PROSTATIC NEOPLASMS Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.2563  0.357
2011 Steinmetz NF, Ablack AL, Hickey JL, Ablack J, Manocha B, Mymryk JS, Luyt LG, Lewis JD. Viral Nanoparticles: Intravital Imaging of Human Prostate Cancer Using Viral Nanoparticles Targeted to Gastrin-Releasing Peptide Receptors (Small 12/2011) Small. 7: 1602-1602. DOI: 10.1002/Smll.201190042  0.72
2010 Behnam Azad B, Rota VA, Breadner D, Dhanvantari S, Luyt LG. Design, synthesis and in vitro characterization of Glucagon-Like Peptide-1 derivatives for pancreatic beta cell imaging by SPECT. Bioorganic & Medicinal Chemistry. 18: 1265-72. PMID 20056547 DOI: 10.1016/J.Bmc.2009.12.032  0.439
2010 Amadei GA, Cho CF, Lewis JD, Luyt LG. A fast, reproducible and low-cost method for sequence deconvolution of 'on-bead' peptides via 'on-target' maldi-TOF/TOF mass spectrometry. Journal of Mass Spectrometry : Jms. 45: 241-51. PMID 20041400 DOI: 10.1002/Jms.1708  0.364
2010 Tichauer KM, Hickey JL, Hoffman L, Lawrence KS, Luyt LG, Lee T. Novel Near-Infrared Fluorescent Agent for Imaging Human Prostate Carcinoma in an Athymic Mouse Model Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2010.Btud5  0.339
2010 Simpson EJ, Breadner D, Hickey JL, Luyt LG. Isomers of the (NαHis)Ac chelator upon coordination of 99mTc/Re(CO)3 Nuclear Medicine and Biology. 37: 685. DOI: 10.1016/J.Nucmedbio.2010.04.069  0.747
2009 Martin AL, Hickey JL, Ablack AL, Lewis JD, Luyt LG, Gillies ER. Synthesis of bombesin-functionalized iron oxide nanoparticles and their specific uptake in prostate cancer cells. Journal of Nanoparticle Research : An Interdisciplinary Forum For Nanoscale Science and Technology. 12: 1599-1608. PMID 22328862 DOI: 10.1007/S11051-009-9681-3  0.734
2009 Rosita D, Dewit MA, Luyt LG. Fluorine and rhenium substituted ghrelin analogues as potential imaging probes for the growth hormone secretagogue receptor. Journal of Medicinal Chemistry. 52: 2196-203. PMID 19323558 DOI: 10.1021/Jm8014519  0.427
2005 Bigott HM, Parent E, Luyt LG, Katzenellenbogen JA, Welch MJ. Design and synthesis of functionalized cyclopentadienyl tricarbonylmetal complexes for technetium-94m PET imaging of estrogen receptors. Bioconjugate Chemistry. 16: 255-64. PMID 15769078 DOI: 10.1021/Bc049770G  0.723
2003 Luyt LG, Bigott HM, Welch MJ, Katzenellenbogen JA. 7alpha- and 17alpha-substituted estrogens containing tridentate tricarbonyl rhenium/technetium complexes: synthesis of estrogen receptor imaging agents and evaluation using microPET with technetium-94m. Bioorganic & Medicinal Chemistry. 11: 4977-89. PMID 14604660 DOI: 10.1016/J.Bmc.2003.09.004  0.51
2003 Gorshkov NI, Lumpov AA, Miroslavov AE, Suglobov DN, Katzenellenbogen JA, Luyt LG. “Scorpion-like” dithiocarbamato-carboxylate ligands for linking M(CO)3 + (M=Tc, Re) Czechoslovak Journal of Physics. 53: A543-A548. DOI: 10.1007/S10582-003-0070-3  0.438
2002 Luyt LG, Katzenellenbogen JA. A trithiolate tripodal bifunctional ligand for the radiolabeling of peptides with gallium(III) Bioconjugate Chemistry. 13: 1140-1145. PMID 12236797 DOI: 10.1021/Bc025552G  0.535
2001 Luyt LG, Katzenellenbogen JA. Synthesis of a functionalized gallium(III) tripodyl complex Journal of Labelled Compounds and Radiopharmaceuticals. 44: S773-S774. DOI: 10.1002/Jlcr.25804401272  0.481
2001 Luyt LG, Mull ES, Katzenellenbogen JA, Bigott HM, Welch MJ. Preparation of cyclopentadienyl tricarbonyl technetium-94m complexes Journal of Labelled Compounds and Radiopharmaceuticals. 44: S489-S490. DOI: 10.1002/Jlcr.25804401173  0.42
2001 Gorshkov NI, Katzenellenbogen JA, Luyt LG, Lumpov AA, Miroslavov AE, Suglobov DN. New dithiocarbamato-carboxylate chelation units for linking M(CO)3+ (M = Tc, Re) species to other molecules Journal of Labelled Compounds and Radiopharmaceuticals. 44: S486-S488. DOI: 10.1002/Jlcr.25804401172  0.413
2000 Hunter DH, Luyt LG. Single isomer technetium-99m tamoxifen conjugates. Bioconjugate Chemistry. 11: 175-81. PMID 10725094 DOI: 10.1021/Bc990110Z  0.704
2000 Hunter DH, Luyt LG. Lysine conjugates for the labelling of peptides with technetium-99m and rhenium Journal of Labelled Compounds and Radiopharmaceuticals. 43: 403-412. DOI: 10.1002/(Sici)1099-1344(20000330)43:4<403::Aid-Jlcr330>3.0.Co;2-M  0.724
1999 Luyt LG, Jenkins HA, Hunter DH. An N2S2 bifunctional chelator for technetium-99m and rhenium: complexation, conjugation, and epimerization to a single isomer. Bioconjugate Chemistry. 10: 470-9. PMID 10346880 DOI: 10.1021/Bc980134Q  0.676
Low-probability matches (unlikely to be authored by this person)
2012 Veiseh M, Breadner D, Ma J, Akentieva N, Savani RC, Harrison R, Mikilus D, Collis L, Gustafson S, Lee TY, Koropatnick J, Luyt LG, Bissell MJ, Turley EA. Imaging of homeostatic, neoplastic, and injured tissues by HA-based probes. Biomacromolecules. 13: 12-22. PMID 22066590 DOI: 10.1021/Bm201143C  0.294
2016 Li F, Cho SJ, Yu L, Hudson RHE, Luyt LG, Pin CL, Kovacs MS, Koropatnick J, Lee T. Evaluation of 6-([18F] fluoroacetamido)-1-hexanoic-anilide (18F-FAHA) as imaging probe in tumor xenograft mice model Proceedings of Spie. 9788: 978814. DOI: 10.1117/12.2216905  0.293
2016 Cho C, Kasai K, Wolfe J, Hornburg K, Bononi F, Luyt L, Pentelute B, Viapiano M, Chiocca E, Lawler S. PS2 - 178 Brevican-Specific Peptides for the Development of Next-Generation Targeted Theranostics for High Grade Gliomas Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 43: S14-S14. DOI: 10.1017/cjn.2016.369  0.275
2016 Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE. Design of a microfluidic chip for magnetic-activated sorting of one-bead-one-compound libraries. Acs Combinatorial Science. PMID 27124678 DOI: 10.1021/Acscombsci.5B00180  0.263
2022 Liu W, Hopkins AM, Yan P, Du S, Luyt LG, Li Y, Hou J. Can machine learning 'transform' peptides/peptidomimetics into small molecules? A case study with ghrelin receptor ligands. Molecular Diversity. PMID 36331785 DOI: 10.1007/s11030-022-10555-w  0.255
2015 Hou JQ, Chen SB, Zan LP, Ou TM, Tan JH, Luyt LG, Huang ZS. Identification of a selective G-quadruplex DNA binder using a multistep virtual screening approach. Chemical Communications (Cambridge, England). 51: 198-201. PMID 25388435 DOI: 10.1039/C4Cc06951J  0.255
2020 Shortt C, Luyt LG, Turley EA, Cowman MK, Kirsch T. A Hyaluronan-binding Peptide (P15-1) Reduces Inflammatory and Catabolic Events in IL-1β-treated Human Articular Chondrocytes. Scientific Reports. 10: 1441. PMID 31996703 DOI: 10.1038/S41598-020-57586-7  0.248
2016 Gavin CT, Ali SN, Tailly T, Olvera-Posada D, Alenezi H, Power NE, Hou J, St Amant AH, Luyt LG, Wood S, Wu C, Razvi H, Leong HS. Novel Methods of Determining Urinary Calculi Composition: Petrographic Thin Sectioning of Calculi and Nanoscale Flow Cytometry Urinalysis. Scientific Reports. 6: 19328. PMID 26771074 DOI: 10.1038/Srep19328  0.247
2009 Hamilton SR, Veiseh M, Tölg C, Tirona R, Richardson J, Brown R, Gonzalez M, Vanzieleghem M, Anderson P, Asculai S, Winnik F, Savani R, Freeman D, Luyt L, Koropatnick J, et al. Pharmacokinetics and pharmacodynamics of hyaluronan infused into healthy human volunteers Open Drug Metabolism Journal. 3: 43-55. DOI: 10.2174/1874073100903010043  0.235
2018 Hauser-Kawaguchi A, Milne M, Li F, Lee TY, Luyt LG. The development of a near infrared inulin optical probe for measuring glomerular filtration rate. International Journal of Biological Macromolecules. PMID 30419331 DOI: 10.1016/J.Ijbiomac.2018.11.034  0.231
2014 Charlton CL, Dhanvantari S, Luyt LG. Evaluation of [68Ga]-DOTA ghrelin (1–19) in LNCaP prostate carcinoma Nuclear Medicine and Biology. 41: 638. DOI: 10.1016/J.Nucmedbio.2014.05.102  0.23
2019 Ghiassian S, Yu L, Gobbo P, Nazemi A, Romagnoli T, Luo W, Luyt LG, Workentin MS. Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential as F-Labeled Positron Emission Tomography Probes via I-SPANC. Acs Omega. 4: 19106-19115. PMID 31763533 DOI: 10.1021/acsomega.9b02322  0.131
1994 Dinescu L, Mezo A, Luyt LG, Lemieux RP. A convenient synthesis of 6,6′-dialkoxythioindigo dyes suitable for doping into a liquid crystal host Tetrahedron Letters. 35: 7549-7552. DOI: 10.1016/S0040-4039(00)78340-7  0.042
2010 DINESCU L, MEZO A, LUYT LG, LEMIEUX RP. ChemInform Abstract: A Convenient Synthesis of 6,6′-Dialkoxythioindigo Dyes (VII) Suitable for Doping into a Liquid Crystal Host. Cheminform. 26: no-no. DOI: 10.1002/CHIN.199511217  0.04
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