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Theodore Jardetzky - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Website:
https://med.stanford.edu/profiles/theodore-jardetzky
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78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chin A, Liu J, Jardetzky T, Johnson DC, Vanarsdall A. Identification of functionally important domains of human cytomegalovirus gO that act after trimer binding to receptors. Plos Pathogens. 18: e1010452. PMID 35452493 DOI: 10.1371/journal.ppat.1010452  0.333
2021 Liu J, Vanarsdall A, Chen DH, Chin A, Johnson D, Jardetzky TS. Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha. Mbio. 12: e0262521. PMID 34700375 DOI: 10.1128/mBio.02625-21  0.353
2020 Connolly SA, Jardetzky TS, Longnecker R. The structural basis of herpesvirus entry. Nature Reviews. Microbiology. PMID 33087881 DOI: 10.1038/s41579-020-00448-w  0.379
2020 Chen J, Schaller S, Jardetzky TS, Longnecker R. EBV gH/gL and KSHV gH/gL bind to different sites on EphA2 to trigger fusion. Journal of Virology. PMID 32847853 DOI: 10.1128/Jvi.01454-20  0.367
2018 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Chi YI, Stauffacher C, Strominger JL, Wiley DC. Pillars Article: Three-Dimensional Structure of a Human Class II Histocompatibility Molecule Complexed with Superantigen. . 1994. 368: 711-718. Journal of Immunology (Baltimore, Md. : 1950). 201: 1819-1826. PMID 30224361  0.523
2017 Sathiyamoorthy K, Jiang J, Möhl BS, Chen J, Zhou ZH, Longnecker R, Jardetzky TS. Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies. Proceedings of the National Academy of Sciences of the United States of America. PMID 28939750 DOI: 10.1073/Pnas.1704661114  0.383
2017 Jardetzky T, Kuhn R, Lamb R. Editorial overview: Virus structure and functions. Current Opinion in Virology. 24: ix. PMID 28743434 DOI: 10.1016/J.Coviro.2017.07.006  0.331
2017 Sathiyamoorthy K, Chen J, Longnecker R, Jardetzky TS. The COMPLEXity in herpesvirus entry. Current Opinion in Virology. 24: 97-104. PMID 28538165 DOI: 10.1016/J.Coviro.2017.04.006  0.3
2016 Sathiyamoorthy K, Hu YX, Möhl BS, Chen J, Longnecker R, Jardetzky TS. Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins. Nature Communications. 7: 13557. PMID 27929061 DOI: 10.1038/Ncomms13557  0.375
2016 Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, et al. Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791117 DOI: 10.1073/Pnas.1609449113  0.315
2016 Adu-Gyamfi E, Kim LS, Jardetzky TS, Lamb RA. Mutagenesis of Paramyxovirus Hemagglutinin-Neuraminidase Membrane Proximal Stalk Region Influences Stability, Receptor Binding and Neuraminidase Activity. Journal of Virology. PMID 27334593 DOI: 10.1128/Jvi.00896-16  0.326
2016 Pennington LF, Tarchevskaya S, Brigger D, Sathiyamoorthy K, Graham MT, Nadeau KC, Eggel A, Jardetzky TS. Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange. Nature Communications. 7: 11610. PMID 27194387 DOI: 10.1038/Ncomms11610  0.323
2016 Möhl BS, Chen J, Sathiyamoorthy K, Jardetzky TS, Longnecker R. Structural and Mechanistic Insights into the Tropism of Epstein-Barr Virus. Molecules and Cells. PMID 27094060 DOI: 10.14348/Molcells.2016.0066  0.424
2015 Möhl BS, Schröter C, Klupp BG, Fuchs W, Mettenleiter TC, Jardetzky TS, Longnecker R. Comparative mutagenesis of Pseudorabies and Epstein-Barr virus gH identifies a structural determinant within domain III of gH required for surface expression and entry function. Journal of Virology. PMID 26656711 DOI: 10.1128/Jvi.03032-15  0.3
2015 Rowe CL, Chen J, Jardetzky TS, Longnecker R. Membrane anchoring of Epstein-Barr virus gp42 inhibits fusion with B cells even with increased flexibility allowed by engineered spacers. Mbio. 6. PMID 25564465 DOI: 10.1128/Mbio.02285-14  0.326
2015 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Pillars article: three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 1993. 364: 33-39. Journal of Immunology (Baltimore, Md. : 1950). 194: 5-11. PMID 25527791  0.523
2015 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 Journal of Immunology. 194: 5-11.  0.525
2014 Möhl BS, Sathiyamoorthy K, Jardetzky TS, Longnecker R. The conserved disulfide bond within domain II of Epstein-Barr virus gH has divergent roles in membrane fusion with epithelial cells and B cells. Journal of Virology. 88: 13570-9. PMID 25231307 DOI: 10.1128/Jvi.02272-14  0.309
2014 Sathiyamoorthy K, Jiang J, Hu YX, Rowe CL, Möhl BS, Chen J, Jiang W, Mellins ED, Longnecker R, Zhou ZH, Jardetzky TS. Assembly and architecture of the EBV B cell entry triggering complex. Plos Pathogens. 10: e1004309. PMID 25144748 DOI: 10.1371/Journal.Ppat.1004309  0.32
2013 Welch BD, Yuan P, Bose S, Kors CA, Lamb RA, Jardetzky TS. Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain. Plos Pathogens. 9: e1003534. PMID 23950713 DOI: 10.1371/Journal.Ppat.1003534  0.303
2013 Rowe CL, Connolly SA, Chen J, Jardetzky TS, Longnecker R. A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion Virology. 436: 118-126. PMID 23200314 DOI: 10.1016/J.Virol.2012.10.039  0.33
2012 Wurzburg BA, Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS. An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation Journal of Biological Chemistry. 287: 36251-36257. PMID 22948141 DOI: 10.1074/jbc.M112.407502  0.342
2011 Bose S, Welch BD, Kors CA, Yuan P, Jardetzky TS, Lamb RA. Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion. Journal of Virology. 85: 12855-66. PMID 21994464 DOI: 10.1128/Jvi.06350-11  0.315
2011 Rowe CL, Matsuura H, Jardetzky TS, Longnecker R. Investigation of the function of the putative self-association site of Epstein-Barr virus (EBV) glycoprotein 42 (gp42) Virology. 415: 122-131. PMID 21550622 DOI: 10.1016/J.Virol.2011.04.003  0.575
2011 Backovic M, Jardetzky TS. Class III viral membrane fusion proteins Advances in Experimental Medicine and Biology. 950: 91-101. PMID 21506008 DOI: 10.1007/978-94-007-0782-5_3  0.308
2011 Connolly SA, Jackson JO, Jardetzky TS, Longnecker R. Fusing structure and function: A structural view of the herpesvirus entry machinery Nature Reviews Microbiology. 9: 369-381. PMID 21478902 DOI: 10.1038/Nrmicro2548  0.305
2011 Park M, Matsuura H, Lamb RA, Barron AE, Jardetzky TS. A fluorescence polarization assay using an engineered human respiratory syncytial virus F protein as a direct screening platform. Analytical Biochemistry. 409: 195-201. PMID 20971054 DOI: 10.1016/J.Ab.2010.10.020  0.486
2010 Matsuura H, Kirschner AN, Longnecker R, Jardetzky TS. Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex Proceedings of the National Academy of Sciences of the United States of America. 107: 22641-22646. PMID 21149717 DOI: 10.1073/Pnas.1011806108  0.756
2010 Liu F, Marquardt G, Kirschner AN, Longnecker R, Jardetzky TS. Mapping the N-terminal residues of Epstein-Barr virus gp42 that bind gH/gL by using fluorescence polarization and cell-based fusion assays Journal of Virology. 84: 10375-10385. PMID 20668073 DOI: 10.1128/Jvi.00381-10  0.704
2010 Shaw PL, Kirschner AN, Jardetzky TS, Longnecker R. Characteristics of Epstein-Barr virus envelope protein gp42 Virus Genes. 40: 307-319. PMID 20162447 DOI: 10.1007/S11262-010-0455-X  0.711
2009 Wurzburg BA, Jardetzky TS. Conformational Flexibility in Immunoglobulin E-Fc3-4 Revealed in Multiple Crystal Forms Journal of Molecular Biology. 393: 176-190. PMID 19682998 DOI: 10.1016/j.jmb.2009.08.012  0.327
2009 Sorem J, Jardetzky TS, Longnecker R. Cleavage and secretion of Epstein-Barr virus glycoprotein 42 promote membrane fusion with B lymphocytes Journal of Virology. 83: 6664-6672. PMID 19369343 DOI: 10.1128/Jvi.00195-09  0.362
2009 Kirschner AN, Sorem J, Longnecker R, Jardetzky TS. Structure of Epstein-Barr Virus Glycoprotein 42 Suggests a Mechanism for Triggering Receptor-Activated Virus Entry Structure. 17: 223-233. PMID 19217393 DOI: 10.1016/J.Str.2008.12.010  0.749
2009 Backovic M, Longnecker R, Jardetzky TS. Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B Proceedings of the National Academy of Sciences of the United States of America. 106: 2880-2885. PMID 19196955 DOI: 10.1073/Pnas.0810530106  0.304
2009 Reimer JJ, Backovic M, Deshpande CG, Jardetzky T, Longnecker R. Analysis of Epstein-Barr virus glycoprotein B functional domains via linker insertion mutagenesis. Journal of Virology. 83: 734-47. PMID 18987135 DOI: 10.1128/Jvi.01817-08  0.383
2007 Backovic M, Leser GP, Lamb RA, Longnecker R, Jardetzky TS. Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins. Virology. 368: 102-13. PMID 17655906 DOI: 10.1016/J.Virol.2007.06.031  0.31
2007 Kirschner AN, Lowrey AS, Longnecker R, Jardetzky TS. Binding-site interactions between epstein-barr virus fusion proteins gp42 and gH/gL reveal a peptide that inhibits both epithelial and B-cell membrane fusion Journal of Virology. 81: 9216-9229. PMID 17581996 DOI: 10.1128/Jvi.00575-07  0.701
2007 Lerch TF, Shimasaki S, Woodruff TK, Jardetzky TS. Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions Journal of Biological Chemistry. 282: 15930-15939. PMID 17409095 DOI: 10.1074/Jbc.M700737200  0.748
2007 Lerch TF, Xu M, Jardetzky TS, Mayo KE, Radhakrishnan I, Kazer R, Shea LD, Woodruff TK. The structures that underlie normal reproductive function Molecular and Cellular Endocrinology. 267: 1-5. PMID 17140726 DOI: 10.1016/J.Mce.2006.10.018  0.702
2006 Kirschner AN, Omerovi? J, Popov B, Longnecker R, Jardetzky TS. Soluble Epstein-Barr virus glycoproteins gH, gL, and gp42 form a 1:1:1 stable complex that acts like soluble gp42 in B-cell fusion but not in epithelial cell fusion Journal of Virology. 80: 9444-9454. PMID 16973550 DOI: 10.1128/Jvi.00572-06  0.679
2006 Lin SJ, Lerch TF, Cook RW, Jardetzky TS, Woodruff TK. The structural basis of TGF-β, bone morphogenetic protein, and activin ligand binding Reproduction. 132: 179-190. PMID 16885528 DOI: 10.1530/Rep.1.01072  0.706
2005 Thompson TB, Lerch TF, Cook RW, Woodruff TK, Jardetzky TS. The structure of the follistatin: Activin complex reveals antagonism of both type I and type II receptor binding Developmental Cell. 9: 535-543. PMID 16198295 DOI: 10.1016/J.Devcel.2005.09.008  0.784
2005 Cook RW, Thompson TB, Kurup SP, Jardetzky TS, Woodruff TK. Structural basis for a functional antagonist in the transforming growth factor beta superfamily. The Journal of Biological Chemistry. 280: 40177-86. PMID 16186117 DOI: 10.1074/Jbc.M504591200  0.611
2005 Yuan P, Thompson TB, Wurzburg BA, Paterson RG, Lamb RA, Jardetzky TS. Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose. Structure (London, England : 1993). 13: 803-15. PMID 15893670 DOI: 10.1016/J.Str.2005.02.019  0.598
2005 Cook RW, Thompson TB, Kurup SP, Jardetzky TS, Woodruff TK. Structural basis for a functional antagonist in the transforming growth factor β superfamily Journal of Biological Chemistry. 280: 40177-40186. DOI: 10.1074/jbc.M504591200  0.533
2004 Thompson TB, Cook RW, Chapman SC, Jardetzky TS, Woodruff TK. Beta A versus beta B: Is it merely a matter of expression? Molecular and Cellular Endocrinology. 225: 9-17. PMID 15451562 DOI: 10.1016/J.Mce.2004.02.007  0.581
2004 Cook RW, Thompson TB, Jardetzky TS, Woodruff TK. Molecular biology of inhibin action Seminars in Reproductive Medicine. 22: 269-276. PMID 15319829 DOI: 10.1055/S-2004-831902  0.607
2004 Silva AL, Omerovi? J, Jardetzky TS, Longnecker R. Mutational analyses of Epstein-Barr virus glycoprotein 42 reveal functional domains not involved in receptor binding but required for membrane fusion Journal of Virology. 78: 5946-5956. PMID 15140992 DOI: 10.1128/Jvi.78.11.5946-5956.2004  0.417
2003 Ressing ME, Van Leeuwen D, Verreck FAW, Gomez R, Heemskerk B, Toebes M, Mullen MM, Jardetzky TS, Longnecker R, Schilham MW, Ottenhoff THM, Neefjes J, Schumacher TN, Hutt-Fletcher LM, Wiertz EJHJ. Interference with T cell receptor-HLA-DR interactions by Epstein-Barr virus gp42 results in reduced T helper cell recognition Proceedings of the National Academy of Sciences of the United States of America. 100: 11583-11588. PMID 14504389 DOI: 10.1073/Pnas.2034960100  0.688
2003 McShane MP, Mullen MM, Haan KM, Jardetzky TS, Longnecker R. Mutational analysis of the HLA class II interaction with Epstein-Barr virus glycoprotein 42 Journal of Virology. 77: 7655-7662. PMID 12805465 DOI: 10.1128/Jvi.77.13.7655-7662.2003  0.691
2003 Thompson TB, Woodruff TK, Jardetzky TS. Structures of an ActRIIB:activin a complex reveal a novel binding mode for TGF-β ligand:receptor interactions Embo Journal. 22: 1555-1566. PMID 12660162 DOI: 10.1093/Emboj/Cdg156  0.639
2002 Jardetzky T. HIV: Conformational camouflage Nature. 420: 623-624. PMID 12478278 DOI: 10.1038/420623A  0.305
2002 Wurzburg BA, Jardetzky TS. Structural insights into the interactions between human IgE and its high affinity receptor FcεRI Molecular Immunology. 38: 1063-1072. PMID 11955598 DOI: 10.1016/S0161-5890(02)00035-4  0.332
2002 Mullen MM, Haan KM, Longnecker R, Jardetzky TS. Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1 Molecular Cell. 9: 375-385. PMID 11864610 DOI: 10.1016/S1097-2765(02)00465-3  0.73
2001 Garman SC, Sechi S, Kinet JP, Jardetzky TS. The analysis of the human high affinity IgE receptor FcεRIα from multiple crystal forms Journal of Molecular Biology. 311: 1049-1062. PMID 11531339 DOI: 10.1006/Jmbi.2001.4929  0.68
2000 Wurzburg BA, Garman SC, Jardetzky TS. Structure of the human IgE-Fc Cε3-Cε4 reveals conformational flexibility in the antibody effector domains Immunity. 13: 375-385. PMID 11021535 DOI: 10.1016/S1074-7613(00)00037-6  0.671
2000 Garman SC, Wurzburg BA, Tarchevskaya SS, Klnet JP, Jardetzky TS. Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα Nature. 406: 259-266. PMID 10917520 DOI: 10.1038/35018500  0.696
1999 Garman SC, Kinet JP, Jardetzky TS. The crystal structure of the human high-affinity IgE receptor (FcεRIα) Annual Review of Immunology. 17: 973-976. PMID 10358779 DOI: 10.1146/Annurev.Immunol.17.1.973  0.686
1999 Baker KA, Dutch RE, Lamb RA, Jardetzky TS. Structural basis for paramyxovirus-mediated membrane fusion. Molecular Cell. 3: 309-19. PMID 10198633 DOI: 10.1016/S1097-2765(00)80458-X  0.584
1999 Sundberg E, Jardetzky TS. Structural basis for HLA-DQ binding by the streptococcal superantigen SSA Nature Structural Biology. 6: 123-129. PMID 10048922 DOI: 10.1038/5809  0.349
1998 Garman SC, Kinet JP, Jardetzky TS. Crystal structure of the human high-affinity IgE receptor Cell. 95: 951-961. PMID 9875849 DOI: 10.1016/S0092-8674(00)81719-5  0.682
1997 Jardetzky T. Not just another Fab: The crystal structure of a TcR-MHC-peptide complex Structure. 5: 159-163. PMID 9032079 DOI: 10.1016/S0969-2126(97)00175-5  0.394
1996 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides. Proceedings of the National Academy of Sciences of the United States of America. 93: 734-8. PMID 8570625 DOI: 10.1073/Pnas.93.2.734  0.557
1995 Brown JH, Jardetzky TS, Stern LJ, Gorga JC, Strominger JL, Wiley DC. Human class II MHC molecule HLA-DR1: X-ray structure determined from three crystal forms. Acta Crystallographica. Section D, Biological Crystallography. 51: 946-61. PMID 15299764 DOI: 10.1107/S0907444995002289  0.532
1995 Schafer PH, Pierce SK, Jardetzky TS. The structure of MHC class II: A role for dimer of dimers Seminars in Immunology. 7: 389-398. PMID 8775464 DOI: 10.1006/Smim.1995.0043  0.311
1994 Jardetzky TS, Brown JH, Gorga JC, Stern LJ, Urban RG, Chi YI, Stauffacher C, Strominger JL, Wiley DC. Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. Nature. 368: 711-8. PMID 8152483 DOI: 10.1038/368711A0  0.586
1994 Stern LJ, Brown JH, Jardetzky TS, Gorga JC, Urban RG, Strominger JL, Wiley DC. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature. 368: 215-21. PMID 8145819 DOI: 10.1038/368215A0  0.566
1994 Thibodeau J, Cloutier I, Lavoie PM, Labrecque N, Mourad W, Jardetzky T, Sékaly RP. Subsets of HLA-DR1 molecules defined by SEB and TSST-1 binding Science. 266: 1874-1878. PMID 7997881 DOI: 10.1126/Science.7997881  0.461
1993 Guo HC, Madden DR, Silver ML, Jardetzky TS, Gorga JC, Strominger JL, Wiley DC. Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, HLA-A*0201, and HLA-B*2705. Proceedings of the National Academy of Sciences of the United States of America. 90: 8053-7. PMID 8367462 DOI: 10.1073/Pnas.90.17.8053  0.566
1993 Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 364: 33-9. PMID 8316295 DOI: 10.1038/364033A0  0.59
1992 Guo HC, Jardetzky TS, Garrett TP, Lane WS, Strominger JL, Wiley DC. Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle. Nature. 360: 364-6. PMID 1448153 DOI: 10.1038/360364A0  0.533
1991 Jardetzky TS, Lane WS, Robinson RA, Madden DR, Wiley DC. Identification of self peptides bound to purified HLA-B27. Nature. 353: 326-9. PMID 1922338 DOI: 10.1038/353326A0  0.513
1991 Gorga JC, Brown JH, Jardetzky T, Wiley DC, Strominger JL. Crystallization of HLA-DR antigens. Research in Immunology. 142: 401-7. PMID 1754711 DOI: 10.1016/0923-2494(91)90038-K  0.544
1990 Jardetzky TS, Gorga JC, Busch R, Rothbard J, Strominger JL, Wiley DC. Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding. The Embo Journal. 9: 1797-803. PMID 2189723  0.565
1990 Jardetzky T, Gorga J, Busch R, Rothbard J, Strominger J, Wiley D. Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding. The Embo Journal. 9: 1797-1803. DOI: 10.1002/J.1460-2075.1990.Tb08304.X  0.565
1988 Brown JH, Jardetzky T, Saper MA, Samraoui B, Bjorkman PJ, Wiley DC. A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules. Nature. 332: 845-50. PMID 3258651 DOI: 10.1038/332845A0  0.646
1987 Priestle JP, Grütter MG, White JL, Vincent MG, Kania M, Wilson E, Jardetzky TS, Kirschner K, Jansonius JN. Three-dimensional structure of the bifunctional enzyme N-(5'-phosphoribosyl)anthranilate isomerase-indole-3-glycerol-phosphate synthase from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 84: 5690-4. PMID 3303031 DOI: 10.1073/Pnas.84.16.5690  0.527
1987 Kirschner K, Szadkowski H, Jardetzky TS, Hager V. Phosphoribosylanthranilate isomerase-indoleglycerol-phosphate synthase from Escherichia coli. Methods in Enzymology. 142: 386-97. PMID 3298981 DOI: 10.1016/S0076-6879(87)42050-8  0.415
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