John C. Guatelli - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Microbiology Biology

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Firrito C, Bertelli C, Rosa A, Chande A, Ananth S, van Dijk H, Fackler OT, Stoneham C, Singh R, Guatelli J, Pizzato M. A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation. Viruses. 15. PMID 36992361 DOI: 10.3390/v15030652  0.469
2022 Ramirez PW, Vollbrecht T, Acosta FM, Suarez M, Angerstein AO, Wallace J, O' Connell RM, Guatelli J. Nef enhances HIV-1 replication and infectivity independently of SERINC5 in CEM T cells. Virology. 578: 154-162. PMID 36577173 DOI: 10.1016/j.virol.2022.12.008  0.402
2022 Oom AL, Stoneham CA, Lewinski MK, Richards A, Wozniak JM, Shams-Ud-Doha K, Gonzalez DJ, Krogan NJ, Guatelli J. Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression. Molecular & Cellular Proteomics : McP. 100194. PMID 35017099 DOI: 10.1016/j.mcpro.2022.100194  0.362
2021 Stoneham CA, Langer S, De Jesus PD, Wozniak JM, Lapek J, Deerinck T, Thor A, Pache L, Chanda SK, Gonzalez DJ, Ellisman M, Guatelli J. A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor. Plos Pathogens. 17: e1009409. PMID 34843601 DOI: 10.1371/journal.ppat.1009409  0.418
2021 Park SH, Siddiqi H, Castro DV, De Angelis AA, Oom AL, Stoneham CA, Lewinski MK, Clark AE, Croker BA, Carlin AF, Guatelli J, Opella SJ. Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity. Plos Pathogens. 17: e1009519. PMID 34003853 DOI: 10.1371/journal.ppat.1009519  0.312
2021 Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Becker ME, Pratt D, Churas C, Rosenthal SB, Liu S, Weston S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, ... ... Guatelli J, et al. Functional landscape of SARS-CoV-2 cellular restriction. Molecular Cell. PMID 33930332 DOI: 10.1016/j.molcel.2021.04.008  0.309
2020 Vollbrecht T, Angerstein AO, Menke B, Kumar NM, de Oliveira MF, Richman DD, Guatelli JC. Inconsistent reversal of HIV-1 latency ex vivo by antigens of HIV-1, CMV, and other infectious agents. Retrovirology. 17: 36. PMID 33228686 DOI: 10.1186/s12977-020-00545-x  0.394
2020 Martin-Sancho L, Lewinski MK, Pache L, Stoneham CA, Yin X, Pratt D, Churas C, Rosenthal SB, Liu S, De Jesus PD, O'Neill AM, Gounder AP, Nguyen C, Pu Y, Oom AL, ... ... Guatelli J, et al. Functional Landscape of SARS-CoV-2 Cellular Restriction. Biorxiv : the Preprint Server For Biology. PMID 33024967 DOI: 10.1101/2020.09.29.319566  0.348
2020 Angerstein AO, Stoneham CA, Ramirez PW, Guatelli JC, Vollbrecht T. Sensitivity to monoclonal antibody 447-52D and an open env trimer conformation correlate poorly with inhibition of HIV-1 infectivity by SERINC5. Virology. 548: 73-81. PMID 32838948 DOI: 10.1016/J.Virol.2020.06.007  0.381
2020 Kwon Y, Kaake RM, Echeverria I, Suarez M, Karimian Shamsabadi M, Stoneham C, Ramirez PW, Kress J, Singh R, Sali A, Krogan N, Guatelli J, Jia X. Structural basis of CD4 downregulation by HIV-1 Nef. Nature Structural & Molecular Biology. PMID 32719457 DOI: 10.1038/S41594-020-0463-Z  0.541
2020 Stoneham CA, Ramirez PW, Singh R, Suarez M, Debray A, Lim C, Jia X, Xiong Y, Guatelli J. A conserved acidic cluster motif in SERINC5 confers partial resistance to antagonism by HIV-1 Nef. Journal of Virology. PMID 31941773 DOI: 10.1128/Jvi.01554-19  0.539
2019 Ramirez PW, Sharma S, Singh R, Stoneham CA, Vollbrecht T, Guatelli J. Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins. Cells. 8. PMID 31480747 DOI: 10.3390/Cells8091020  0.489
2019 Sharma S, Jafari M, Bangar A, William K, Guatelli J, Lewinski MK. The C-terminal end of HIV-1 viral protein U (Vpu) encodes a clade-specific determinant to antagonize BST-2 and facilitate virion release. Journal of Virology. PMID 30867310 DOI: 10.1128/Jvi.02315-18  0.495
2019 Tokarev A, Guatelli J. Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence. Cellular Logistics. 1: 90-102. PMID 21922073 DOI: 10.4161/Cl.1.3.16708  0.581
2018 Sharma S, Lewinski MK, Guatelli J. An N-glycosylated form of SERINC5 is specifically incorporated into HIV-1 virions. Journal of Virology. PMID 30158294 DOI: 10.1128/Jvi.00753-18  0.479
2018 Singh R, Stoneham C, Lim C, Jia X, Guenaga J, Wyatt R, Wertheim JO, Xiong Y, Guatelli J. Phosphoserine acidic cluster motifs bind distinct basic regions on the µ subunits of clathrin adaptor protein complexes. The Journal of Biological Chemistry. PMID 30135209 DOI: 10.1074/Jbc.Ra118.003080  0.547
2017 Rizk MG, Basler CF, Guatelli J. Cooperation of the Ebola proteins VP40 and GP1,2 with BST2 to activate NF-κβ independently of virus-like particle trapping. Journal of Virology. PMID 28878074 DOI: 10.1128/Jvi.01308-17  0.457
2017 Lapek JD, Lewinski MK, Wozniak JM, Guatelli J, Gonzalez DJ. Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Vpr. Molecular & Cellular Proteomics : McP. PMID 28606917 DOI: 10.1074/Mcp.M116.066019  0.52
2017 Stoneham CA, Singh R, Jia X, Xiong Y, Guatelli J. Endocytic Activity of HIV-1 Vpu: Phosphoserine-dependent Interactions with Clathrin Adaptors. Traffic (Copenhagen, Denmark). PMID 28504462 DOI: 10.1111/Tra.12495  0.537
2016 Murrell B, Vollbrecht T, Guatelli J, Wertheim JO. The Evolutionary Histories of Antiretroviral Proteins SERINC3 and SERINC5 Do Not Support an Evolutionary Arms Race in Primates. Journal of Virology. PMID 27356902 DOI: 10.1128/Jvi.00972-16  0.429
2016 Ball KA, Johnson JR, Lewinski MK, Guatelli J, Verschueren E, Krogan NJ, Jacobson MP. Non-degradative Ubiquitination of Protein Kinases. Plos Computational Biology. 12: e1004898. PMID 27253329 DOI: 10.1371/Journal.Pcbi.1004898  0.321
2015 Tokarev A, Stoneham C, Lewinski MK, Mukim A, Deshmukh S, Vollbrecht T, Spina CA, Guatelli J. Pharmacologic Inhibition of Nedd8 Activation Enzyme Exposes CD4-induced Epitopes within Env on Cells Expressing HIV-1. Journal of Virology. PMID 26676780 DOI: 10.1128/Jvi.02736-15  0.527
2015 Lewinski MK, Jafari M, Zhang H, Opella SJ, Guatelli J. Membrane Anchoring by a C-terminal Tryptophan Enables HIV-1 Vpu to Displace Bone Marrow Stromal Antigen 2 (BST2) from Sites of Viral Assembly. The Journal of Biological Chemistry. 290: 10919-33. PMID 25759385 DOI: 10.1074/Jbc.M114.630095  0.497
2014 Jia X, Weber E, Tokarev A, Lewinski M, Rizk M, Suarez M, Guatelli J, Xiong Y. Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1. Elife. 3: e02362. PMID 24843023 DOI: 10.7554/Elife.02362  0.567
2014 Jafari M, Guatelli J, Lewinski MK. Activities of transmitted/founder and chronic clade B HIV-1 Vpu and a C-terminal polymorphism specifically affecting virion release. Journal of Virology. 88: 5062-78. PMID 24574397 DOI: 10.1128/Jvi.03472-13  0.509
2014 Abdel-Mohsen M, Deng X, Liegler T, Guatelli JC, Salama MS, Ghanem Hel-D, Rauch A, Ledergerber B, Deeks SG, Günthard HF, Wong JK, Pillai SK. Effects of alpha interferon treatment on intrinsic anti-HIV-1 immunity in vivo. Journal of Virology. 88: 763-7. PMID 24155399 DOI: 10.1128/Jvi.02687-13  0.462
2014 Jia X, Weber E, Tokarev A, Lewinski M, Rizk M, Suarez M, Guatelli J, Xiong Y. Author response: Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1 Elife. DOI: 10.7554/Elife.02362.020  0.45
2013 Sherrill-Mix S, Lewinski MK, Famiglietti M, Bosque A, Malani N, Ocwieja KE, Berry CC, Looney D, Shan L, Agosto LM, Pace MJ, Siliciano RF, O'Doherty U, Guatelli J, Planelles V, et al. HIV latency and integration site placement in five cell-based models. Retrovirology. 10: 90. PMID 23953889 DOI: 10.1186/1742-4690-10-90  0.406
2013 Tokarev A, Suarez M, Kwan W, Fitzpatrick K, Singh R, Guatelli J. Stimulation of NF-κB activity by the HIV restriction factor BST2. Journal of Virology. 87: 2046-57. PMID 23221546 DOI: 10.1128/Jvi.02272-12  0.464
2013 Singh RK, Lau D, Noviello CM, Ghosh P, Guatelli JC. Surface expression in CEM T cells of CD8 chimeras containing the MHC-I CD, Nef, or the MHC-I CD-Nef chimeric sequence as cytoplasmic domains was measured by flow cytometry. Plos One. DOI: 10.1371/Journal.Pone.0008364.G003  0.366
2012 Miyakawa K, Sawasaki T, Matsunaga S, Tokarev A, Quinn G, Kimura H, Nomaguchi M, Adachi A, Yamamoto N, Guatelli J, Ryo A. Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu. Science Signaling. 5: ra73. PMID 23047923 DOI: 10.1126/Scisignal.2003212  0.537
2012 Jia X, Singh R, Homann S, Yang H, Guatelli J, Xiong Y. Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef. Nature Structural & Molecular Biology. 19: 701-6. PMID 22705789 DOI: 10.1038/Nsmb.2328  0.536
2012 Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, et al. Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: 3035-40. PMID 22315404 DOI: 10.1073/Pnas.1111573109  0.487
2012 Skasko M, Wang Y, Tian Y, Tokarev A, Munguia J, Ruiz A, Stephens EB, Opella SJ, Guatelli J. HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions. The Journal of Biological Chemistry. 287: 58-67. PMID 22072710 DOI: 10.1074/Jbc.M111.296772  0.459
2012 Homann S, Smith D, Little S, Richman D, Guatelli J. Upregulation of BST-2/Tetherin by HIV Infection In Vivo Journal of Virology. 86: 13889-13889. DOI: 10.1128/jvi.02451-12  0.336
2011 Homann S, Smith D, Little S, Richman D, Guatelli J. Upregulation of BST-2/Tetherin by HIV infection in vivo. Journal of Virology. 85: 10659-68. PMID 21849457 DOI: 10.1128/Jvi.05524-11  0.503
2011 Lau D, Kwan W, Guatelli J. Role of the endocytic pathway in the counteraction of BST-2 by human lentiviral pathogens Journal of Virology. 85: 9834-9846. PMID 21813615 DOI: 10.1128/Jvi.02633-10  0.517
2011 Skasko M, Tokarev A, Chen CC, Fischer WB, Pillai SK, Guatelli J. BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-action. Virology. 411: 65-77. PMID 21237475 DOI: 10.1016/J.Virol.2010.12.038  0.447
2011 Tokarev AA, Munguia J, Guatelli JC. Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu. Journal of Virology. 85: 51-63. PMID 20980512 DOI: 10.1128/Jvi.01795-10  0.474
2011 Hauser H, Lopez LA, Yang SJ, Oldenburg JE, Exline CM, Guatelli JC, Cannon PM. Correction: HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment Retrovirology. 85. DOI: 10.1186/1742-4690-8-85  0.345
2010 Ruiz A, Lau D, Mitchell RS, Hill MS, Schmitt K, Guatelli JC, Stephens EB. BST-2 mediated restriction of simian-human immunodeficiency virus. Virology. 406: 312-21. PMID 20708210 DOI: 10.1016/J.Virol.2010.07.021  0.513
2010 Evans DT, Serra-Moreno R, Singh RK, Guatelli JC. BST-2/tetherin: a new component of the innate immune response to enveloped viruses. Trends in Microbiology. 18: 388-96. PMID 20688520 DOI: 10.1016/J.Tim.2010.06.010  0.521
2010 Casartelli N, Sourisseau M, Feldmann J, Guivel-Benhassine F, Mallet A, Marcelin AG, Guatelli J, Schwartz O. Tetherin restricts productive HIV-1 cell-to-cell transmission. Plos Pathogens. 6: e1000955. PMID 20585562 DOI: 10.1371/Journal.Ppat.1000955  0.494
2010 Hauser H, Lopez LA, Yang SJ, Oldenburg JE, Exline CM, Guatelli JC, Cannon PM. HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment. Retrovirology. 7: 51. PMID 20529266 DOI: 10.1186/1742-4690-7-51  0.479
2010 Fitzpatrick K, Skasko M, Deerinck TJ, Crum J, Ellisman MH, Guatelli J. Direct restriction of virus release and incorporation of the interferon-induced protein BST-2 into HIV-1 particles. Plos Pathogens. 6: e1000701. PMID 20221443 DOI: 10.1371/Journal.Ppat.1000701  0.573
2010 Ruiz A, Guatelli JC, Stephens EB. The Vpu protein: new concepts in virus release and CD4 down-modulation. Current Hiv Research. 8: 240-52. PMID 20201792 DOI: 10.2174/157016210791111124  0.553
2010 Guatelli J. How innate immunity can inhibit the release of HIV-1 from infected cells. The New England Journal of Medicine. 362: 553-4. PMID 20147723 DOI: 10.1056/Nejmcibr0911557  0.506
2009 Singh RK, Lau D, Noviello CM, Ghosh P, Guatelli JC. An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex. Plos One. 4: e8364. PMID 20020046 DOI: 10.1371/Journal.Pone.0008364  0.757
2009 Miyakawa K, Ryo A, Murakami T, Ohba K, Yamaoka S, Fukuda M, Guatelli J, Yamamoto N. BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction. Plos Pathogens. 5: e1000700. PMID 20019814 DOI: 10.1371/Journal.Ppat.1000700  0.502
2009 Guatelli JC. Interactions of viral protein U (Vpu) with cellular factors. Current Topics in Microbiology and Immunology. 339: 27-45. PMID 20012522 DOI: 10.1007/978-3-642-02175-6_2  0.538
2009 Tokarev A, Skasko M, Fitzpatrick K, Guatelli J. Antiviral activity of the interferon-induced cellular protein BST-2/tetherin. Aids Research and Human Retroviruses. 25: 1197-210. PMID 19929170 DOI: 10.1089/Aid.2009.0253  0.556
2009 Mitchell RS, Katsura C, Skasko MA, Fitzpatrick K, Lau D, Ruiz A, Stephens EB, Margottin-Goguet F, Benarous R, Guatelli JC. Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking. Plos Pathogens. 5: e1000450. PMID 19478868 DOI: 10.1371/Journal.Ppat.1000450  0.475
2008 Ruiz A, Hill MS, Schmitt K, Guatelli J, Stephens EB. Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in virus release. Virology. 378: 58-68. PMID 18579178 DOI: 10.1016/J.Virol.2008.05.022  0.471
2008 Mitchell RS, Chaudhuri R, Lindwasser OW, Tanaka KA, Lau D, Murillo R, Bonifacino JS, Guatelli JC. Competition model for upregulation of the major histocompatibility complex class II-associated invariant chain by human immunodeficiency virus type 1 Nef. Journal of Virology. 82: 7758-67. PMID 18524831 DOI: 10.1128/Jvi.02668-07  0.415
2008 Van Damme N, Goff D, Katsura C, Jorgenson RL, Mitchell R, Johnson MC, Stephens EB, Guatelli J. The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host & Microbe. 3: 245-52. PMID 18342597 DOI: 10.1016/J.Chom.2008.03.001  0.572
2008 Noviello CM, Benichou S, Guatelli JC. Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunit. Journal of Virology. 82: 1249-58. PMID 18057255 DOI: 10.1128/Jvi.00660-07  0.745
2007 Van Damme N, Guatelli J. HIV-1 Vpu inhibits accumulation of the envelope glycoprotein within clathrin-coated, Gag-containing endosomes. Cellular Microbiology. 10: 1040-57. PMID 18076669 DOI: 10.1111/J.1462-5822.2007.01101.X  0.556
2007 Noviello CM, Pond SL, Lewis MJ, Richman DD, Pillai SK, Yang OO, Little SJ, Smith DM, Guatelli JC. Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1. Journal of Virology. 81: 4776-86. PMID 17329339 DOI: 10.1128/Jvi.01793-06  0.729
2007 Dueck M, Guatelli J. Evidence against a direct antiviral activity of the proteasome during the early steps of HIV-1 replication. Virology. 361: 1-8. PMID 17316734 DOI: 10.1016/J.Virol.2007.01.018  0.416
2007 Burtey A, Rappoport JZ, Bouchet J, Basmaciogullari S, Guatelli J, Simon SM, Benichou S, Benmerah A. Dynamic interaction of HIV-1 Nef with the clathrin-mediated endocytic pathway at the plasma membrane. Traffic (Copenhagen, Denmark). 8: 61-76. PMID 17140399 DOI: 10.1111/J.1600-0854.2006.00512.X  0.521
2006 Day JR, Van Damme N, Guatelli JC. The effect of the membrane-proximal tyrosine-based sorting signal of HIV-1 gp41 on viral infectivity depends on sequences within gp120. Virology. 354: 316-27. PMID 16905171 DOI: 10.1016/J.Virol.2006.06.023  0.507
2006 Day JR, Martínez LE, Sásik R, Hitchin DL, Dueck ME, Richman DD, Guatelli JC. A computer-based, image-analysis method to quantify HIV-1 infection in a single-cycle infectious center assay. Journal of Virological Methods. 137: 125-33. PMID 16876264 DOI: 10.1016/J.Jviromet.2006.06.019  0.45
2006 Coleman SH, Madrid R, Van Damme N, Mitchell RS, Bouchet J, Servant C, Pillai S, Benichou S, Guatelli JC. Modulation of cellular protein trafficking by human immunodeficiency virus type 1 Nef: role of the acidic residue in the ExxxLL motif. Journal of Virology. 80: 1837-49. PMID 16439540 DOI: 10.1128/Jvi.80.4.1837-1849.2006  0.533
2006 Coleman SH, Hitchin D, Noviello CM, Guatelli JC. HIV-1 Nef stabilizes AP-1 on membranes without inducing ARF1-independent de novo attachment. Virology. 345: 148-55. PMID 16253302 DOI: 10.1016/J.Virol.2005.09.045  0.744
2005 Coleman SH, Van Damme N, Day JR, Noviello CM, Hitchin D, Madrid R, Benichou S, Guatelli JC. Leucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexes. Journal of Virology. 79: 2066-78. PMID 15681409 DOI: 10.1128/Jvi.79.4.2066-2078.2005  0.749
2005 Madrid R, Janvier K, Hitchin D, Day J, Coleman S, Noviello C, Bouchet J, Benmerah A, Guatelli J, Benichou S. Nef-induced alteration of the early/recycling endosomal compartment correlates with enhancement of HIV-1 infectivity. The Journal of Biological Chemistry. 280: 5032-44. PMID 15569681 DOI: 10.1074/Jbc.M401202200  0.771
2004 Day JR, Münk C, Guatelli JC. The membrane-proximal tyrosine-based sorting signal of human immunodeficiency virus type 1 gp41 is required for optimal viral infectivity. Journal of Virology. 78: 1069-79. PMID 14722262 DOI: 10.1128/Jvi.78.3.1069-1079.2004  0.505
2003 Ali A, Pillai S, Ng H, Lubong R, Richman DD, Jamieson BD, Ding Y, McElrath MJ, Guatelli JC, Yang OO. Broadly increased sensitivity to cytotoxic T lymphocytes resulting from Nef epitope escape mutations. Journal of Immunology (Baltimore, Md. : 1950). 171: 3999-4005. PMID 14530319 DOI: 10.4049/Jimmunol.171.8.3999  0.497
2003 Janvier K, Craig H, Hitchin D, Madrid R, Sol-Foulon N, Renault L, Cherfils J, Cassel D, Benichou S, Guatelli J. HIV-1 Nef stabilizes the association of adaptor protein complexes with membranes. The Journal of Biological Chemistry. 278: 8725-32. PMID 12486136 DOI: 10.1074/Jbc.M210115200  0.503
2001 Janvier K, Craig H, Le Gall S, Benarous R, Guatelli J, Schwartz O, Benichou S. Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP. Journal of Virology. 75: 3971-6. PMID 11264386 DOI: 10.1128/Jvi.75.8.3971-3976.2001  0.505
2001 Coleman SH, Day JR, Guatelli JC. The HIV-1 Nef protein as a target for antiretroviral therapy Expert Opinion On Therapeutic Targets. 5: 1-22. DOI: 10.1517/14728222.5.1.1  0.547
2000 Erdtmann L, Janvier K, Raposo G, Craig HM, Benaroch P, Berlioz-Torrent C, Guatelli JC, Benarous R, Benichou S. Two independent regions of HIV-1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex. Traffic (Copenhagen, Denmark). 1: 871-83. PMID 11208076 DOI: 10.1034/J.1600-0854.2000.011106.X  0.549
2000 Craig HM, Reddy TR, Riggs NL, Dao PP, Guatelli JC. Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif. Virology. 271: 9-17. PMID 10814565 DOI: 10.1006/Viro.2000.0277  0.477
1999 Craig HM, Pandori MW, Riggs NL, Richman DD, Guatelli JC. Analysis of the SH3-binding region of HIV-1 nef: partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket. Virology. 262: 55-63. PMID 10489340 DOI: 10.1006/Viro.1999.9897  0.412
1999 Riggs NL, Craig HM, Pandori MW, Guatelli JC. The dileucine-based sorting motif in HIV-1 Nef is not required for down-regulation of class I MHC. Virology. 258: 203-7. PMID 10366557 DOI: 10.1006/Viro.1999.9736  0.511
1998 Pandori M, Craig H, Moutouh L, Corbeil J, Guatelli J. Virological importance of the protease-cleavage site in human immunodeficiency virus type 1 Nef is independent of both intravirion processing and CD4 down-regulation. Virology. 251: 302-16. PMID 9837795 DOI: 10.1006/Viro.1998.9407  0.504
1998 Riggs NL, Little SJ, Richman DD, Guatelli JC. Cell-associated viral rNA expression during acute infection with HIV type 1 Aids Research and Human Retroviruses. 14: 1141-1149. PMID 9737585 DOI: 10.1089/Aid.1998.14.1141  0.425
1998 Craig HM, Pandori MW, Guatelli JC. Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. Proceedings of the National Academy of Sciences of the United States of America. 95: 11229-34. PMID 9736718 DOI: 10.1073/Pnas.95.19.11229  0.58
1998 Günthard HF, Wong JK, Ignacio CC, Guatelli JC, Riggs NL, Havlir DV, Richman DD. Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy Journal of Virology. 72: 2422-2428. PMID 9499103 DOI: 10.1128/Jvi.72.3.2422-2428.1998  0.374
1997 Guatelli JC. The positive influence of Nef on viral infectivity Research in Virology. 148: 34-37. PMID 9017831 DOI: 10.1016/S0923-2516(97)81910-3  0.367
1996 Pandori MW, Fitch NJ, Craig HM, Richman DD, Spina CA, Guatelli JC. Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein. Journal of Virology. 70: 4283-90. PMID 8676450 DOI: 10.1128/Jvi.70.7.4283-4290.1996  0.508
1996 Riggs NL, Guatelli JC. Production and characterization of high-titer stocks of rev-defective HIV-1 Virology. 217: 602-606. PMID 8610453 DOI: 10.1006/Viro.1996.0156  0.501
1996 Pandori MW, Fitch NJ, Craig HM, Richman DD, Spina CA, Guatelli JC. Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein. Journal of Virology. 70: 4283-4290. DOI: 10.1128/jvi.70.7.4283-4290.1996  0.323
1995 Luznik L, Kraus G, Guatelli J, Richman D, Wong-Staal F. Tat-independent replication of human immunodeficiency viruses Journal of Clinical Investigation. 95: 328-332. PMID 7814633 DOI: 10.1172/Jci117660  0.488
1995 Spina CA, Guatelli JC, Richman DD. Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro Journal of Virology. 69: 2977-2988. PMID 7707524 DOI: 10.1128/Jvi.69.5.2977-2988.1995  0.506
1995 Chowers MY, Pandori MW, Spina CA, Richman DD, Guatelli JC. The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation. Virology. 212: 451-7. PMID 7571414 DOI: 10.1006/Viro.1995.1502  0.487
1994 Chowers MY, Spina CA, Kwoh TJ, Fitch NJ, Richman DD, Guatelli JC. Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. Journal of Virology. 68: 2906-14. PMID 8151761 DOI: 10.1128/Jvi.68.5.2906-2914.1994  0.443
1994 Riggs NL, Little SJ, Richman DD, Guatelli JC. Biological importance and cooperativity of HIV-1 regulatory gene splice acceptors Virology. 202: 264-271. PMID 8009838 DOI: 10.1006/Viro.1994.1342  0.343
1994 Little SJ, Riggs NL, Chowers MY, Fitch NJ, Richman DD, Spina CA, Guatelli JC. Cell surface CD4 downregulation and resistance to superinfection induced by a defective provirus of HIV-1. Virology. 205: 578-82. PMID 7975260 DOI: 10.1006/Viro.1994.1683  0.502
1994 Spina CA, Kwoh TJ, Chowers MY, Guatelli JC, Richman DD. The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes Journal of Experimental Medicine. 179: 115-123. PMID 7903679 DOI: 10.1084/Jem.179.1.115  0.52
1993 Bahner I, Zhou C, Yu XJ, Hao QL, Guatelli JC, Kohn DB. Comparison of trans-dominant inhibitory mutant human immunodeficiency virus type 1 genes expressed by retroviral vectors in human T lymphocytes Journal of Virology. 67: 3199-3207. PMID 8388497 DOI: 10.1128/Jvi.67.6.3199-3207.1993  0.456
1993 Meylan PRA, Guatelli JC, Munis JR, Richman DD, Kornbluth RS. Mechanisms for the inhibition of HIV replication by interferons-α, -β, and -γ in primary human macrophages Virology. 193: 138-148. PMID 7679856 DOI: 10.1006/Viro.1993.1110  0.492
1992 Munis JR, Kornbluth RS, Guatelli JC, Richman DD. Ordered appearance of human immunodeficiency virus type 1 nucleic acids following high multiplicity infection of macrophages Journal of General Virology. 73: 1899-1906. PMID 1645135 DOI: 10.1099/0022-1317-73-8-1899  0.46
1991 Gingeras TR, Prodanovich P, Latimer T, Guatelli JC, Richman DD, Barringer KJ. Use of self-sustained sequence replication amplification reaction to analyze and detect mutations in zidovudine-resistant human immunodeficiency virus Journal of Infectious Diseases. 164: 1066-1074. PMID 1955709 DOI: 10.1093/Infdis/164.6.1066  0.41
1990 Guatelli JC, Gingeras TR, Richman DD. Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells Journal of Virology. 64: 4093-4098. PMID 2384914 DOI: 10.1128/Jvi.64.9.4093-4098.1990  0.4
1989 Guatelli JC, Gingeras TR, Richman DD. Nucleic acid amplification in vitro: Detection of sequences with low copy numbers and application to diagnosis of human immunodeficiency virus type 1 infection Clinical Microbiology Reviews. 2: 217-226. PMID 2650862 DOI: 10.1128/Cmr.2.2.217  0.357
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