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Richard J Sove - Publications

Affiliations: 
Medical Biophysics University of Western Ontario, London, Ontario, Canada 
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sové RJ, Verma BK, Wang H, Ho WJ, Yarchoan M, Popel AS. Virtual clinical trials of anti-PD-1 and anti-CTLA-4 immunotherapy in advanced hepatocellular carcinoma using a quantitative systems pharmacology model. Journal For Immunotherapy of Cancer. 10. PMID 36323435 DOI: 10.1136/jitc-2022-005414  0.374
2022 Ruiz-Martinez A, Gong C, Wang H, Sové RJ, Mi H, Kimko H, Popel AS. Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model. Plos Computational Biology. 18: e1010254. PMID 35867773 DOI: 10.1371/journal.pcbi.1010254  0.44
2022 Kowalewska PM, Piazza JE, Milkovich SL, Sové RJ, Wang L, Whitehead SN, Ellis CG. Spectroscopy detects skeletal muscle microvascular dysfunction during onset of sepsis in a rat fecal peritonitis model. Scientific Reports. 12: 6339. PMID 35428849 DOI: 10.1038/s41598-022-10208-w  0.646
2022 Christie JR, Kong I, Mawdsley L, Milkovich S, Doornekamp A, Baek J, Fraser GM, Ellis CG, Sové RJ. Optical method to determine in vivo capillary hematocrit, hemoglobin concentration, and 3-D network geometry in skeletal muscle. Microcirculation (New York, N.Y. : 1994). e12751. PMID 35146836 DOI: 10.1111/micc.12751  0.679
2021 Sové RJ, Milkovich S, Nikolov HN, Holdsworth DW, Ellis CG, Fraser GM. Localized Oxygen Exchange Platform for Intravital Video Microscopy Investigations of Microvascular Oxygen Regulation. Frontiers in Physiology. 12: 654928. PMID 34168569 DOI: 10.3389/fphys.2021.654928  0.716
2021 Russell McEvoy GM, Shogan H, Sové RJ, Fraser GM. Development and validation of a novel microfluidic device for the manipulation of skeletal muscle microvascular blood flow in vivo. Microcirculation (New York, N.Y. : 1994). e12698. PMID 33817909 DOI: 10.1111/micc.12698  0.708
2021 Zhao C, Medeiros TX, Sové RJ, Annex BH, Popel AS. A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization. Iscience. 24: 102112. PMID 33659877 DOI: 10.1016/j.isci.2021.102112  0.435
2021 Wang H, Ma H, Sové RJ, Emens LA, Popel AS. Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer. Journal For Immunotherapy of Cancer. 9. PMID 33579739 DOI: 10.1136/jitc-2020-002100  0.394
2020 Ma H, Wang H, Sové RJ, Wang J, Giragossian C, Popel AS. Combination therapy with T cell engager and PD-L1 blockade enhances the antitumor potency of T cells as predicted by a QSP model. Journal For Immunotherapy of Cancer. 8. PMID 32859743 DOI: 10.1136/Jitc-2020-001141  0.409
2020 Sové RJ, Jafarnejad M, Zhao C, Wang H, Ma H, Popel AS. QSP-IO: A quantitative systems pharmacology toolbox for mechanistic multi-scale modeling for immuno-oncology applications. Cpt: Pharmacometrics & Systems Pharmacology. PMID 32618119 DOI: 10.1002/psp4.12546  0.424
2020 Ma H, Wang H, Sove RJ, Jafarnejad M, Tsai CH, Wang J, Giragossian C, Popel AS. A Quantitative Systems Pharmacology Model of T Cell Engager Applied to Solid Tumor. The Aaps Journal. 22: 85. PMID 32533270 DOI: 10.1208/S12248-020-00450-3  0.417
2020 Wang H, Sové RJ, Jafarnejad M, Rahmeh S, Jaffee EM, Stearns V, Torres ETR, Connolly RM, Popel AS. Conducting a Virtual Clinical Trial in HER2-Negative Breast Cancer Using a Quantitative Systems Pharmacology Model With an Epigenetic Modulator and Immune Checkpoint Inhibitors. Frontiers in Bioengineering and Biotechnology. 8: 141. PMID 32158754 DOI: 10.3389/Fbioe.2020.00141  0.416
2019 Zhao C, Mirando AC, Sové RJ, Medeiros TX, Annex BH, Popel AS. A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology. Plos Computational Biology. 15: e1007468. PMID 31738746 DOI: 10.1371/Journal.Pcbi.1007468  0.405
2019 Jafarnejad M, Sové RJ, Danilova L, Mirando AC, Zhang Y, Yarchoan M, Tran PT, Pandey NB, Fertig EJ, Popel AS. Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma. Npj Systems Biology and Applications. 5: 29. PMID 31452933 DOI: 10.1038/s41540-019-0107-2  0.393
2018 Sové RJ, Drakos NE, Fraser GM, Ellis CG. Using digital inpainting to estimate incident light intensity for the calculation of red blood cell oxygen saturation from microscopy images. Journal of Biophotonics. e201800103. PMID 29797788 DOI: 10.1002/Jbio.201800103  0.689
2016 Sové RJ, Goldman D, Fraser GM. A Computational Model of the Effect of Capillary Density Variability on Oxygen Transport, Glucose Uptake, and Insulin Sensitivity in Prediabetes. Microcirculation (New York, N.Y. : 1994). PMID 27991711 DOI: 10.1111/micc.12342  0.698
2016 Sové RJ, Fraser GM, Goldman D, Ellis CG. Finite Element Model of Oxygen Transport for the Design of Geometrically Complex Microfluidic Devices Used in Biological Studies. Plos One. 11: e0166289. PMID 27829071 DOI: 10.1371/journal.pone.0166289  0.709
2013 Sove RJ, Ghonaim N, Goldman D, Ellis CG. A computational model of a microfluidic device to measure the dynamics of oxygen-dependent ATP release from erythrocytes. Plos One. 8: e81537. PMID 24312316 DOI: 10.1371/journal.pone.0081537  0.68
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