Sandy Chang
Affiliations: | Cancer Genetics | University of Texas, Austin, Texas |
Website:
http://www3.mdanderson.org/public/genedev/public_html/chang.htmlGoogle:
"Sandy Chang"Parents
Sign in to add mentor| Ronald A. DePinho | post-doc | University of Texas | (podlevsky) Delete Edit |
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Publications
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| Rai R, Sodeinde T, Boston A, et al. (2023) Telomeres cooperate with the nuclear envelope to maintain genome stability. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300184 |
| Takasugi T, Gu P, Liang F, et al. (2023) Pot1b -/- tumors activate G-quadruplex-induced DNA damage to promote telomere hyper-elongation. Nucleic Acids Research |
| Rai R, Biju K, Sun W, et al. (2023) Homology directed telomere clustering, ultrabright telomere formation and nuclear envelope rupture in cells lacking TRF2 and RAP1. Nature Communications. 14: 2144 |
| Gu P, Jia S, Takasugi T, et al. (2021) Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres. Nature Communications. 12: 5514 |
| Cicconi A, Rai R, Xiong X, et al. (2020) Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly. Nature Communications. 11: 5861 |
| Cicconi A, Chang S. (2020) Shelterin and the replisome: at the intersection of telomere repair and replication. Current Opinion in Genetics & Development. 60: 77-84 |
| Rai R, Gu P, Broton C, et al. (2019) The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function. Cell Reports. 29: 3708-3725.e5 |
| Chan EM, Shibue T, McFarland JM, et al. (2019) WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature |
| Gu P, Jia S, Takasugi T, et al. (2018) CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. Aging Cell. e12783 |
| Hu C, Rai R, Huang C, et al. (2017) Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex. Cell Research |