| Year |
Citation |
Score |
| 2024 |
Liang F, Rai R, Sodeinde T, Chang S. TRF2-RAP1 represses RAD51-dependent homology-directed telomere repair by promoting BLM-mediated D-loop unwinding and inhibiting BLM-DNA2-dependent 5'-end resection. Nucleic Acids Research. PMID 39082275 DOI: 10.1093/nar/gkae642 |
0.418 |
|
| 2023 |
Rai R, Sodeinde T, Boston A, Chang S. Telomeres cooperate with the nuclear envelope to maintain genome stability. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300184. PMID 38047499 DOI: 10.1002/bies.202300184 |
0.386 |
|
| 2023 |
Takasugi T, Gu P, Liang F, Staco I, Chang S. Pot1b -/- tumors activate G-quadruplex-induced DNA damage to promote telomere hyper-elongation. Nucleic Acids Research. PMID 37560909 DOI: 10.1093/nar/gkad648 |
0.462 |
|
| 2023 |
Rai R, Biju K, Sun W, Sodeinde T, Al-Hiysat A, Morgan J, Ye X, Li X, Chen Y, Chang S. Homology directed telomere clustering, ultrabright telomere formation and nuclear envelope rupture in cells lacking TRF2 and RAP1. Nature Communications. 14: 2144. PMID 37059728 DOI: 10.1038/s41467-023-37761-w |
0.401 |
|
| 2021 |
Gu P, Jia S, Takasugi T, Tesmer VM, Nandakumar J, Chen Y, Chang S. Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres. Nature Communications. 12: 5514. PMID 34535663 DOI: 10.1038/s41467-021-25799-7 |
0.381 |
|
| 2020 |
Cicconi A, Rai R, Xiong X, Broton C, Al-Hiyasat A, Hu C, Dong S, Sun W, Garbarino J, Bindra RS, Schildkraut C, Chen Y, Chang S. Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly. Nature Communications. 11: 5861. PMID 33203878 DOI: 10.1038/s41467-020-19674-0 |
0.426 |
|
| 2020 |
Cicconi A, Chang S. Shelterin and the replisome: at the intersection of telomere repair and replication. Current Opinion in Genetics & Development. 60: 77-84. PMID 32171974 DOI: 10.1016/J.Gde.2020.02.016 |
0.477 |
|
| 2019 |
Rai R, Gu P, Broton C, Kumar-Sinha C, Chen Y, Chang S. The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function. Cell Reports. 29: 3708-3725.e5. PMID 31825846 DOI: 10.1016/J.Celrep.2019.11.012 |
0.496 |
|
| 2019 |
Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, ... ... Chang S, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. PMID 30971823 DOI: 10.1038/S41586-019-1102-X |
0.426 |
|
| 2018 |
Gu P, Jia S, Takasugi T, Smith E, Nandakumar J, Hendrickson E, Chang S. CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. Aging Cell. e12783. PMID 29774655 DOI: 10.1111/Acel.12783 |
0.426 |
|
| 2017 |
Hu C, Rai R, Huang C, Broton C, Long J, Xu Y, Xue J, Lei M, Chang S, Chen Y. Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex. Cell Research. PMID 29160297 DOI: 10.1038/Cr.2017.144 |
0.429 |
|
| 2017 |
Chen C, Gu P, Wu J, Chen X, Niu S, Sun H, Wu L, Li N, Peng J, Shi S, Fan C, Huang M, Wong CC, Gong Q, Kumar-Sinha C, ... ... Chang S, et al. Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer. Nature Communications. 8: 14929. PMID 28393832 DOI: 10.1038/Ncomms14929 |
0.416 |
|
| 2017 |
Rai R, Chang S. Probing the Telomere Damage Response. Methods in Molecular Biology (Clifton, N.J.). 1587: 133-138. PMID 28324505 DOI: 10.1007/978-1-4939-6892-3_13 |
0.353 |
|
| 2017 |
Rai R, Multani AS, Chang S. Cytogenetic Analysis of Telomere Dysfunction. Methods in Molecular Biology (Clifton, N.J.). 1587: 127-131. PMID 28324504 DOI: 10.1007/978-1-4939-6892-3_12 |
0.349 |
|
| 2017 |
Rai R, Hu C, Broton C, Chen Y, Lei M, Chang S. NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres. Molecular Cell. PMID 28216226 DOI: 10.1016/J.Molcel.2017.01.016 |
0.463 |
|
| 2016 |
Gu P, Wang Y, Bisht KK, Wu L, Kukova L, Smith EM, Xiao Y, Bailey SM, Lei M, Nandakumar J, Chang S. Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis. Oncogene. PMID 27869160 DOI: 10.1038/Onc.2016.405 |
0.54 |
|
| 2016 |
Wang Y, Wang X, Flores ER, Yu J, Chang S. Dysfunctional telomeres induce p53-dependent and independent apoptosis to compromise cellular proliferation and inhibit tumor formation. Aging Cell. PMID 27113195 DOI: 10.1111/Acel.12476 |
0.392 |
|
| 2016 |
Rai R, Chen Y, Lei M, Chang S. TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions. Nature Communications. 7: 10881. PMID 26941064 DOI: 10.1038/Ncomms10881 |
0.495 |
|
| 2015 |
Rai R, Chang S. Monitoring the DNA Damage Response at Dysfunctional Telomeres. Methods in Molecular Biology (Clifton, N.J.). 1343: 175-80. PMID 26420717 DOI: 10.1007/978-1-4939-2963-4_14 |
0.488 |
|
| 2014 |
Gupta R, Dong Y, Solomon PD, Wettersten HI, Cheng CJ, Min JN, Henson J, Dogra SK, Hwang SH, Hammock BD, Zhu LJ, Reddel RR, Saltzman WM, Weiss RH, Chang S, et al. Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A. Proceedings of the National Academy of Sciences of the United States of America. 111: E3062-71. PMID 25024194 DOI: 10.1073/Pnas.1411370111 |
0.343 |
|
| 2014 |
Lee Y, Brown EJ, Chang S, McKinnon PJ. Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7836-44. PMID 24899707 DOI: 10.1523/Jneurosci.4245-13.2014 |
0.421 |
|
| 2013 |
Wang Y, Sharpless N, Chang S. p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses. The Journal of Clinical Investigation. 123: 4489-501. PMID 24091330 DOI: 10.1172/Jci69574 |
0.414 |
|
| 2013 |
Wan B, Yin J, Horvath K, Sarkar J, Chen Y, Wu J, Wan K, Lu J, Gu P, Yu EY, Lue NF, Chang S, Liu Y, Lei M. SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres. Cell Reports. 4: 861-9. PMID 24012755 DOI: 10.1016/J.Celrep.2013.08.017 |
0.427 |
|
| 2013 |
Min JN, Tian Y, Xiao Y, Wu L, Li L, Chang S. The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability. Cell Research. 23: 1396-413. PMID 23979016 DOI: 10.1038/Cr.2013.113 |
0.516 |
|
| 2013 |
Gu P, Chang S. Functional characterization of human CTC1 mutations reveals novel mechanisms responsible for the pathogenesis of the telomere disease Coats plus. Aging Cell. 12: 1100-9. PMID 23869908 DOI: 10.1111/Acel.12139 |
0.421 |
|
| 2013 |
Chang S. Cancer chromosomes going to POT1. Nature Genetics. 45: 473-5. PMID 23619786 DOI: 10.1038/Ng.2617 |
0.468 |
|
| 2013 |
Gu P, Deng W, Lei M, Chang S. Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres. Cell Research. 23: 705-19. PMID 23459151 DOI: 10.1038/Cr.2013.31 |
0.508 |
|
| 2013 |
Akbay EA, Peña CG, Ruder D, Michel JA, Nakada Y, Pathak S, Multani AS, Chang S, Castrillon DH. Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis. Oncogene. 32: 2211-9. PMID 22689059 DOI: 10.1038/Onc.2012.232 |
0.445 |
|
| 2012 |
Chang S. Chromosome ends teach unexpected lessons on DNA damage signalling. The Embo Journal. 31: 3380-1. PMID 22842787 DOI: 10.1038/Emboj.2012.199 |
0.454 |
|
| 2012 |
Gu P, Min JN, Wang Y, Huang C, Peng T, Chai W, Chang S. CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion. The Embo Journal. 31: 2309-21. PMID 22531781 DOI: 10.1038/Emboj.2012.96 |
0.53 |
|
| 2012 |
Flynn RL, Chang S, Zou L. RPA and POT1: friends or foes at telomeres? Cell Cycle (Georgetown, Tex.). 11: 652-7. PMID 22373525 DOI: 10.4161/Cc.11.4.19061 |
0.488 |
|
| 2011 |
Rai R, Li JM, Zheng H, Lok GT, Deng Y, Huen MS, Chen J, Jin J, Chang S. The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection. Nature Structural & Molecular Biology. 18: 1400-7. PMID 22101936 DOI: 10.1038/Nsmb.2172 |
0.487 |
|
| 2011 |
Wang Y, Shen MF, Chang S. Essential roles for Pot1b in HSC self-renewal and survival. Blood. 118: 6068-77. PMID 21948176 DOI: 10.1182/Blood-2011-06-361527 |
0.442 |
|
| 2011 |
Rai R, Chang S. Probing the telomere damage response. Methods in Molecular Biology (Clifton, N.J.). 735: 145-50. PMID 21461819 DOI: 10.1007/978-1-61779-092-8_14 |
0.456 |
|
| 2011 |
Multani AS, Chang S. Cytogenetic analysis of telomere dysfunction. Methods in Molecular Biology (Clifton, N.J.). 735: 139-43. PMID 21461818 DOI: 10.1007/978-1-61779-092-8_13 |
0.451 |
|
| 2011 |
Flynn RL, Centore RC, O'Sullivan RJ, Rai R, Tse A, Songyang Z, Chang S, Karlseder J, Zou L. TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA. Nature. 471: 532-6. PMID 21399625 DOI: 10.1038/Nature09772 |
0.471 |
|
| 2011 |
Deriano L, Chaumeil J, Coussens M, Multani A, Chou Y, Alekseyenko AV, Chang S, Skok JA, Roth DB. The RAG2 C terminus suppresses genomic instability and lymphomagenesis. Nature. 471: 119-23. PMID 21368836 DOI: 10.1038/Nature09755 |
0.431 |
|
| 2011 |
Chen Y, Rai R, Zhou ZR, Kanoh J, Ribeyre C, Yang Y, Zheng H, Damay P, Wang F, Tsujii H, Hiraoka Y, Shore D, Hu HY, Chang S, Lei M. A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms. Nature Structural & Molecular Biology. 18: 213-21. PMID 21217703 DOI: 10.1038/Nsmb.1974 |
0.421 |
|
| 2010 |
Chang S. The telomere protein tankyrase 1 regulates DNA damage responses at telomeres. Aging. 2: 639-42. PMID 21076181 |
0.388 |
|
| 2010 |
Akhter S, Lam YC, Chang S, Legerski RJ. The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development. Aging Cell. 9: 1047-56. PMID 20854421 DOI: 10.1111/J.1474-9726.2010.00631.X |
0.439 |
|
| 2010 |
Rai R, Zheng H, He H, Luo Y, Multani A, Carpenter PB, Chang S. The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. The Embo Journal. 29: 2598-610. PMID 20588252 DOI: 10.1038/Emboj.2010.142 |
0.5 |
|
| 2010 |
Chan SS, Chang S. Defending the end zone: studying the players involved in protecting chromosome ends. Febs Letters. 584: 3773-8. PMID 20579983 DOI: 10.1016/J.Febslet.2010.06.016 |
0.486 |
|
| 2010 |
Lam YC, Akhter S, Gu P, Ye J, Poulet A, Giraud-Panis MJ, Bailey SM, Gilson E, Legerski RJ, Chang S. SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair. The Embo Journal. 29: 2230-41. PMID 20551906 DOI: 10.1038/Emboj.2010.58 |
0.51 |
|
| 2010 |
Yang G, Chang B, Yang F, Guo X, Cai KQ, Xiao XS, Wang H, Sen S, Hung MC, Mills GB, Chang S, Multani AS, Mercado-Uribe I, Liu J. Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3171-81. PMID 20423983 DOI: 10.1158/1078-0432.Ccr-09-3171 |
0.406 |
|
| 2010 |
Liang Y, Gao H, Lin SY, Peng G, Huang X, Zhang P, Goss JA, Brunicardi FC, Multani AS, Chang S, Li K. BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice. Plos Genetics. 6: e1000826. PMID 20107607 DOI: 10.1371/Journal.Pgen.1000826 |
0.512 |
|
| 2009 |
Atanassov BS, Evrard YA, Multani AS, Zhang Z, Tora L, Devys D, Chang S, Dent SY. Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance. Molecular Cell. 35: 352-64. PMID 19683498 DOI: 10.1016/J.Molcel.2009.06.015 |
0.429 |
|
| 2009 |
Deng Y, Guo X, Ferguson DO, Chang S. Multiple roles for MRE11 at uncapped telomeres. Nature. 460: 914-8. PMID 19633651 DOI: 10.1038/Nature08196 |
0.54 |
|
| 2009 |
He H, Wang Y, Guo X, Ramchandani S, Ma J, Shen MF, Garcia DA, Deng Y, Multani AS, You MJ, Chang S. Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita. Molecular and Cellular Biology. 29: 229-40. PMID 18936156 DOI: 10.1128/Mcb.01400-08 |
0.508 |
|
| 2008 |
Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, Sekiguchi JM, Chang S, Ferguson DO. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell. 135: 85-96. PMID 18854157 DOI: 10.1016/J.Cell.2008.08.015 |
0.44 |
|
| 2008 |
Bhatia B, Jiang M, Suraneni M, Patrawala L, Badeaux M, Schneider-Broussard R, Multani AS, Jeter CR, Calhoun-Davis T, Hu L, Hu J, Tsavachidis S, Zhang W, Chang S, Hayward SW, et al. Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells. The Journal of Biological Chemistry. 283: 27957-72. PMID 18662989 DOI: 10.1074/Jbc.M803467200 |
0.328 |
|
| 2008 |
Deng Y, Chan SS, Chang S. Telomere dysfunction and tumour suppression: the senescence connection. Nature Reviews. Cancer. 8: 450-8. PMID 18500246 DOI: 10.1038/Nrc2393 |
0.505 |
|
| 2008 |
Cosme-Blanco W, Chang S. Dual roles of telomere dysfunction in initiation and suppression of tumorigenesis. Experimental Cell Research. 314: 1973-9. PMID 18448098 DOI: 10.1016/J.Yexcr.2008.03.011 |
0.524 |
|
| 2008 |
Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T, Lasorella A, Iavarone A, Chang S, Hernando E, Pagano M. Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature. 452: 365-9. PMID 18354482 DOI: 10.1038/Nature06641 |
0.354 |
|
| 2008 |
Bhatia B, Multani AS, Patrawala L, Chen X, Calhoun-Davis T, Zhou J, Schroeder L, Schneider-Broussard R, Shen J, Pathak S, Chang S, Tang DG. Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT. International Journal of Cancer. Journal International Du Cancer. 122: 1483-95. PMID 18059027 DOI: 10.1002/Ijc.23222 |
0.334 |
|
| 2007 |
Guo X, Deng Y, Lin Y, Cosme-Blanco W, Chan S, He H, Yuan G, Brown EJ, Chang S. Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. The Embo Journal. 26: 4709-19. PMID 17948054 DOI: 10.1038/Sj.Emboj.7601893 |
0.518 |
|
| 2007 |
Deng Y, Chang S. Role of telomeres and telomerase in genomic instability, senescence and cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 1071-6. PMID 17767195 DOI: 10.1038/Labinvest.3700673 |
0.548 |
|
| 2007 |
Akli S, Van Pelt CS, Bui T, Multani AS, Chang S, Johnson D, Tucker S, Keyomarsi K. Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway. Cancer Research. 67: 7212-22. PMID 17671189 DOI: 10.1158/0008-5472.Can-07-0599 |
0.33 |
|
| 2007 |
Cosme-Blanco W, Shen MF, Lazar AJ, Pathak S, Lozano G, Multani AS, Chang S. Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence. Embo Reports. 8: 497-503. PMID 17396137 DOI: 10.1038/Sj.Embor.7400937 |
0.374 |
|
| 2007 |
Multani AS, Chang S. WRN at telomeres: implications for aging and cancer. Journal of Cell Science. 120: 713-21. PMID 17314245 DOI: 10.1242/Jcs.03397 |
0.454 |
|
| 2006 |
He H, Multani AS, Cosme-Blanco W, Tahara H, Ma J, Pathak S, Deng Y, Chang S. POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination. The Embo Journal. 25: 5180-90. PMID 17053789 DOI: 10.1038/Sj.Emboj.7601294 |
0.517 |
|
| 2006 |
Wu L, Multani AS, He H, Cosme-Blanco W, Deng Y, Deng JM, Bachilo O, Pathak S, Tahara H, Bailey SM, Deng Y, Behringer RR, Chang S. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell. 126: 49-62. PMID 16839876 DOI: 10.1016/J.Cell.2006.05.037 |
0.539 |
|
| 2006 |
Haines BB, Ryu CJ, Chang S, Protopopov A, Luch A, Kang YH, Draganov DD, Fragoso MF, Paik SG, Hong HJ, DePinho RA, Chen J. Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations. Cancer Cell. 9: 109-20. PMID 16473278 DOI: 10.1016/J.Ccr.2006.01.004 |
0.552 |
|
| 2006 |
Wong K, Chang S, Depinho RA. 5 Modeling Cancer and Aging in the Telomerase-deficient Mouse Cold Spring Harbor Monograph Archive. 45: 109-138. DOI: 10.1101/087969810.45.109 |
0.56 |
|
| 2005 |
Laud PR, Multani AS, Bailey SM, Wu L, Ma J, Kingsley C, Lebel M, Pathak S, DePinho RA, Chang S. Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway. Genes & Development. 19: 2560-70. PMID 16264192 DOI: 10.1101/Gad.1321305 |
0.638 |
|
| 2005 |
Chang S. Modeling premature aging syndromes with the telomerase knockout mouse. Current Molecular Medicine. 5: 153-8. PMID 15974868 DOI: 10.2174/1566524053586662 |
0.395 |
|
| 2005 |
Chang S. Modeling aging and cancer in the telomerase knockout mouse. Mutation Research. 576: 39-53. PMID 15927211 DOI: 10.1016/J.Mrfmmm.2004.08.020 |
0.463 |
|
| 2005 |
Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, Hruban RH, Rustgi AK, Chang S, Tuveson DA. Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell. 7: 469-83. PMID 15894267 DOI: 10.1016/J.Ccr.2005.04.023 |
0.399 |
|
| 2005 |
Chang S. A mouse model of Werner Syndrome: what can it tell us about aging and cancer? The International Journal of Biochemistry & Cell Biology. 37: 991-9. PMID 15743673 DOI: 10.1016/J.Biocel.2004.11.007 |
0.427 |
|
| 2004 |
Chang S, Multani AS, Cabrera NG, Naylor ML, Laud P, Lombard D, Pathak S, Guarente L, DePinho RA. Essential role of limiting telomeres in the pathogenesis of Werner syndrome. Nature Genetics. 36: 877-82. PMID 15235603 DOI: 10.1038/Ng1389 |
0.6 |
|
| 2004 |
Akli S, Zheng PJ, Multani AS, Wingate HF, Pathak S, Zhang N, Tucker SL, Chang S, Keyomarsi K. Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer. Cancer Research. 64: 3198-208. PMID 15126360 DOI: 10.1158/0008-5472.Can-03-3672 |
0.321 |
|
| 2004 |
Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, et al. Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects. Cancer Cell. 5: 375-87. PMID 15093544 DOI: 10.1016/S1535-6108(04)00085-6 |
0.436 |
|
| 2004 |
Liu G, Parant JM, Lang G, Chau P, Chavez-Reyes A, El-Naggar AK, Multani A, Chang S, Lozano G. Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nature Genetics. 36: 63-8. PMID 14702042 DOI: 10.1038/Ng1282 |
0.418 |
|
| 2004 |
Miyahara Y, Kazimi N, Multani AS, Pathak S, Chang S, Angkasekwinai Y, Qin X, Ullrich SE. UV-Induced B-Cell Lymphomas in p53 Heterozygous Mice. Blood. 104: 1370-1370. DOI: 10.1182/Blood.V104.11.1370.1370 |
0.325 |
|
| 2003 |
Chang S, Khoo CM, Naylor ML, Maser RS, DePinho RA. Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression. Genes & Development. 17: 88-100. PMID 12514102 DOI: 10.1101/Gad.1029903 |
0.604 |
|
| 2002 |
Chang S, DePinho RA. Telomerase extracurricular activities. Proceedings of the National Academy of Sciences of the United States of America. 99: 12520-2. PMID 12271146 DOI: 10.1073/Pnas.212514699 |
0.617 |
|
| 2002 |
O'Hagan RC, Chang S, Maser RS, Mohan R, Artandi SE, Chin L, DePinho RA. Telomere dysfunction provokes regional amplification and deletion in cancer genomes. Cancer Cell. 2: 149-55. PMID 12204535 DOI: 10.1016/S1535-6108(02)00094-6 |
0.717 |
|
| 2001 |
Ranganathan V, Heine WF, Ciccone DN, Rudolph KL, Wu X, Chang S, Hai H, Ahearn IM, Livingston DM, Resnick I, Rosen F, Seemanova E, Jarolim P, DePinho RA, Weaver DT. Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit. Current Biology : Cb. 11: 962-6. PMID 11448772 DOI: 10.1016/S0960-9822(01)00267-6 |
0.627 |
|
| 2001 |
Chang S, Khoo C, DePinho RA. Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse. Seminars in Cancer Biology. 11: 227-39. PMID 11407947 DOI: 10.1006/Scbi.2000.0374 |
0.612 |
|
| 2000 |
Wong KK, Chang S, Weiler SR, Ganesan S, Chaudhuri J, Zhu C, Artandi SE, Rudolph KL, Gottlieb GJ, Chin L, Alt FW, DePinho RA. Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation. Nature Genetics. 26: 85-8. PMID 10973255 DOI: 10.1038/79232 |
0.756 |
|
| 2000 |
Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature. 406: 641-5. PMID 10949306 DOI: 10.1038/35020592 |
0.733 |
|
| 2000 |
Ferguson DO, Sekiguchi JM, Chang S, Frank KM, Gao Y, DePinho RA, Alt FW. The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. Proceedings of the National Academy of Sciences of the United States of America. 97: 6630-3. PMID 10823907 DOI: 10.1073/Pnas.110152897 |
0.68 |
|
| 2000 |
Rudolph KL, Chang S, Millard M, Schreiber-Agus N, DePinho RA. Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. Science (New York, N.Y.). 287: 1253-8. PMID 10678830 DOI: 10.1126/Science.287.5456.1253 |
0.491 |
|
| 1999 |
Rudolph KL, Chang S, Lee HW, Blasco M, Gottlieb GJ, Greider C, DePinho RA. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell. 96: 701-12. PMID 10089885 DOI: 10.1016/S0092-8674(00)80580-2 |
0.644 |
|
| 1990 |
Aksoy S, Williams S, Chang S, Richards FF. SLACS retrotransposon from Trypanosoma brucei gambiense is similar to mammalian LINEs. Nucleic Acids Research. 18: 785-92. PMID 2156231 DOI: 10.1093/Nar/18.4.785 |
0.308 |
|
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