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Ming Lei - Publications

Affiliations: 
Biological Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
Website:
http://www.biochem.med.umich.edu/?q=ming_lei
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77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen S, Lei M, Liu K, Min J. Structural basis for specific DNA sequence recognition by the transcription factor NFIL3. The Journal of Biological Chemistry. 105776. PMID 38382670 DOI: 10.1016/j.jbc.2024.105776  0.397
2023 Liu K, Li W, Xiao Y, Lei M, Zhang M, Min J. Molecular mechanism of specific DNA sequence recognition by NRF1. Nucleic Acids Research. PMID 38055835 DOI: 10.1093/nar/gkad1162  0.352
2022 Ma Y, Huang C, Tang T, Wu B, Xue H, Cao Y, Wu J, Wan B, Lei M. Structural and functional insights into CST tethering in Tetrahymena thermophila telomerase. Structure (London, England : 1993). 30: 1565-1572.e4. PMID 36459975 DOI: 10.1016/j.str.2022.10.004  0.686
2022 Sun H, Wu Z, Zhou Y, Lu Y, Lu H, Chen H, Shi S, Zeng Z, Wu J, Lei M. Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex. Plos Genetics. 18: e1010308. PMID 35849625 DOI: 10.1371/journal.pgen.1010308  0.47
2021 Shi S, Zhou Y, Lu Y, Sun H, Xue J, Wu Z, Lei M. Ccq1-Raf2 interaction mediates CLRC recruitment to establish heterochromatin at telomeres. Life Science Alliance. 4. PMID 34493579 DOI: 10.26508/lsa.202101106  0.308
2021 Chen Y, Wang Y, Chen J, Zuo W, Fan Y, Huang S, Liu Y, Chen G, Li Q, Li J, Wu J, Bian Q, Huang C, Lei M. The SUN1-SPDYA interaction plays an essential role in meiosis prophase I. Nature Communications. 12: 3176. PMID 34039995 DOI: 10.1038/s41467-021-23550-w  0.321
2021 Zhang M, Lei M, Qin S, Dong A, Yang A, Li Y, Loppnau P, Hughes TR, Min J, Liu Y. Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194688. PMID 33556623 DOI: 10.1016/j.bbagrm.2021.194688  0.318
2020 Ge Y, Wu Z, Chen H, Zhong Q, Shi S, Li G, Wu J, Lei M. Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nature Structural & Molecular Biology. PMID 32661422 DOI: 10.1038/S41594-020-0459-8  0.348
2019 Lei M, Tempel W, Chen S, Liu K, Min J. Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194409. PMID 31356990 DOI: 10.1016/j.bbagrm.2019.194409  0.346
2019 Wan B, Wu J, Meng X, Lei M, Zhao X. Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107. Molecular Cell. 75: 238-251.e5. PMID 31348879 DOI: 10.1016/J.Molcel.2019.05.035  0.751
2019 Liu K, Lei M, Wu Z, Gan B, Cheng H, Li Y, Min J. Structural analyses reveal that MBD3 is a methylated-CG binder. The Febs Journal. PMID 30980593 DOI: 10.1111/febs.14850  0.315
2019 Wang Y, Chen Y, Chen J, Wang L, Nie L, Long J, Chang H, Wu J, Huang C, Lei M. The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope. Nature Communications. 10: 564. PMID 30718482 DOI: 10.1038/S41467-019-08437-1  0.305
2019 Shultis D, Mitra P, Huang X, Johnson J, Khattak NA, Gray F, Piper C, Czajka J, Hansen L, Wan B, Chinnaswamy K, Liu L, Wang M, Pan J, Stuckey J, ... ... Lei M, et al. Changing the Apoptosis Pathway through Evolutionary Protein Design. Journal of Molecular Biology. PMID 30625288 DOI: 10.1016/J.Jmb.2018.12.016  0.713
2018 Li J, Yu Z, Xu J, Feng R, Gao Q, Boczek T, Liu J, Li Z, Wang Q, Lei M, Gong J, Hu H, Minobe E, Ji HL, Kameyama M, et al. The Effect of Ca, Lobe-Specificity, and CaMKII on CaM Binding to Na1.1. International Journal of Molecular Sciences. 19. PMID 30142967 DOI: 10.3390/ijms19092495  0.369
2018 Chen X, Liu L, Chen Y, Yang Y, Yang CY, Guo T, Lei M, Sun H, Wang S. Cyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction. Acs Medicinal Chemistry Letters. 9: 507-511. PMID 29795768 DOI: 10.1021/Acsmedchemlett.8B00152  0.302
2018 Liu K, Xu C, Lei M, Yang A, Loppnau P, Hughes TR, Min J. Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. The Journal of Biological Chemistry. PMID 29567833 DOI: 10.1074/jbc.RA118.001785  0.304
2018 Lei M, Feng Y, Zhou M, Yang Y, Loppnau P, Li Y, Yang Y, Liu Y. Crystal structure of chromo barrel domain of RBBP1. Biochemical and Biophysical Research Communications. PMID 29408527 DOI: 10.1016/j.bbrc.2018.02.016  0.332
2018 Xu C, Liu K, Lei M, Yang A, Li Y, Hughes TR, Min J. DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure (London, England : 1993). 26: 85-95.e3. PMID 29276034 DOI: 10.1016/j.str.2017.11.022  0.321
2017 Chen H, Xue J, Churikov D, Hass EP, Shi S, Lemon LD, Luciano P, Bertuch AA, Zappulla DC, Géli V, Wu J, Lei M. Structural Insights into Yeast Telomerase Recruitment to Telomeres. Cell. PMID 29290466 DOI: 10.1016/J.Cell.2017.12.008  0.758
2017 Hu C, Rai R, Huang C, Broton C, Long J, Xu Y, Xue J, Lei M, Chang S, Chen Y. Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex. Cell Research. PMID 29160297 DOI: 10.1038/Cr.2017.144  0.408
2017 Xue J, Chen H, Wu J, Takeuchi M, Inoue H, Liu Y, Sun H, Chen Y, Kanoh J, Lei M. Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex. Cell Research. PMID 29160296 DOI: 10.1038/Cr.2017.145  0.416
2017 Long J, Huang C, Chen Y, Zhang Y, Shi S, Wu L, Liu Y, Liu C, Wu J, Lei M. Telomeric TERB1-TRF1 interaction is crucial for male meiosis. Nature Structural & Molecular Biology. PMID 29083416 DOI: 10.1038/Nsmb.3496  0.305
2017 Karatas H, Li Y, Liu L, Ji J, Lee S, Chen Y, Yang J, Huang L, Bernard D, Xu J, Townsend EC, Cao F, Ran X, Li X, Wen B, ... ... Lei M, et al. Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction. Journal of Medicinal Chemistry. PMID 28603984 DOI: 10.1021/Acs.Jmedchem.6B01796  0.392
2017 Chen C, Gu P, Wu J, Chen X, Niu S, Sun H, Wu L, Li N, Peng J, Shi S, Fan C, Huang M, Wong CC, Gong Q, Kumar-Sinha C, ... ... Lei M, et al. Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer. Nature Communications. 8: 14929. PMID 28393832 DOI: 10.1038/Ncomms14929  0.383
2017 Huang J, Bley CJ, Rand DP, Chen JJ, Lei M. In Vitro Preparation and Crystallization of Vertebrate Telomerase Subunits. Methods in Molecular Biology (Clifton, N.J.). 1587: 161-169. PMID 28324508 DOI: 10.1007/978-1-4939-6892-3_16  0.467
2017 Tan R, Nakajima S, Wang Q, Sun H, Xue J, Wu J, Hellwig S, Zeng X, Yates NA, Smithgall TE, Lei M, Jiang Y, Levine AS, Su B, Lan L. Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1. Molecular Cell. PMID 28216227 DOI: 10.1016/J.Molcel.2017.01.015  0.419
2016 Yin J, Wan B, Sarkar J, Horvath K, Wu J, Chen Y, Cheng G, Wan K, Chin P, Lei M, Liu Y. Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex. Nucleic Acids Research. PMID 27131364 DOI: 10.1093/Nar/Gkw354  0.732
2016 Rai R, Chen Y, Lei M, Chang S. TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions. Nature Communications. 7: 10881. PMID 26941064 DOI: 10.1038/Ncomms10881  0.426
2016 Li Y, Han J, Zhang Y, Cao F, Liu Z, Li S, Wu J, Hu C, Wang Y, Shuai J, Chen J, Cao L, Li D, Shi P, Tian C, ... Lei M, et al. Structural basis for activity regulation of MLL family methyltransferases. Nature. PMID 26886794 DOI: 10.1038/Nature16952  0.341
2015 Ran X, Liu L, Yang C, Lu J, Chen Y, Lei M, Wang S. Design of High-affinity Stapled Peptides to Target the Repressor Activator Protein 1 (RAP1)/Telomeric Repeat-binding Factor 2 (TRF2) Protein-Protein Interaction in the Shelterin Complex. Journal of Medicinal Chemistry. PMID 26673461 DOI: 10.1021/Acs.Jmedchem.5B01465  0.407
2015 Wan B, Tang T, Upton H, Shuai J, Zhou Y, Li S, Chen J, Brunzelle JS, Zeng Z, Collins K, Wu J, Lei M. The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex. Nature Structural & Molecular Biology. PMID 26551074 DOI: 10.1038/Nsmb.3126  0.697
2015 Deng W, Wu J, Wang F, Kanoh J, Dehe PM, Inoue H, Chen J, Lei M. Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2. Cell Research. 25: 881-4. PMID 26088418 DOI: 10.1038/Cr.2015.76  0.492
2015 Sarkar J, Wan B, Yin J, Vallabhaneni H, Horvath K, Kulikowicz T, Bohr VA, Zhang Y, Lei M, Liu Y. SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates. Nucleic Acids Research. PMID 25990736 DOI: 10.1093/Nar/Gkv522  0.734
2015 Vallabhaneni H, Zhou F, Maul RW, Sarkar J, Yin J, Lei M, Harrington L, Gearhart PJ, Liu Y. Defective repair of uracil causes telomere defects in mouse hematopoietic cells. The Journal of Biological Chemistry. 290: 5502-11. PMID 25572391 DOI: 10.1074/Jbc.M114.607101  0.446
2014 Sommers JA, Banerjee T, Hinds T, Wan B, Wold MS, Lei M, Brosh RM. Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner. The Journal of Biological Chemistry. 289: 19928-41. PMID 24895130 DOI: 10.1074/Jbc.M113.542456  0.741
2014 Huang J, Brown AF, Wu J, Xue J, Bley CJ, Rand DP, Wu L, Zhang R, Chen JJ, Lei M. Structural basis for protein-RNA recognition in telomerase. Nature Structural & Molecular Biology. 21: 507-12. PMID 24793650 DOI: 10.1038/Nsmb.2819  0.421
2014 Yang YW, Flynn RA, Chen Y, Qu K, Wan B, Wang KC, Lei M, Chang HY. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife. 3: e02046. PMID 24521543 DOI: 10.7554/Elife.02046  0.695
2014 Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, et al. Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia. Molecular Cell. 53: 247-61. PMID 24389101 DOI: 10.1016/J.Molcel.2013.12.001  0.32
2013 Wan B, Yin J, Horvath K, Sarkar J, Chen Y, Wu J, Wan K, Lu J, Gu P, Yu EY, Lue NF, Chang S, Liu Y, Lei M. SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres. Cell Reports. 4: 861-9. PMID 24012755 DOI: 10.1016/J.Celrep.2013.08.017  0.771
2013 Gu P, Deng W, Lei M, Chang S. Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres. Cell Research. 23: 705-19. PMID 23459151 DOI: 10.1038/Cr.2013.31  0.435
2013 Lue NF, Yu EY, Lei M. A popular engagement at the ends. Nature Structural & Molecular Biology. 20: 10-2. PMID 23288360 DOI: 10.1038/Nsmb.2483  0.388
2013 Karatas H, Townsend EC, Cao F, Chen Y, Bernard D, Liu L, Lei M, Dou Y, Wang S. High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction. Journal of the American Chemical Society. 135: 669-82. PMID 23210835 DOI: 10.1021/Ja306028Q  0.41
2013 Yang YW, Flynn RA, Chen Y, Qu K, Wan B, Wang KC, Lei M, Chang HY. Author response: Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency Elife. DOI: 10.7554/Elife.02046.013  0.691
2012 Thiel AT, Huang J, Lei M, Hua X. Menin as a hub controlling mixed lineage leukemia Bioessays. 34: 771-780. PMID 22829075 DOI: 10.1002/Bies.201200007  0.348
2012 Huang J, Wan B, Wu L, Yang Y, Dou Y, Lei M. Structural insight into the regulation of MOF in the male-specific lethal complex and the non-specific lethal complex. Cell Research. 22: 1078-81. PMID 22547026 DOI: 10.1038/Cr.2012.72  0.68
2012 Huang J, Gurung B, Wan B, Matkar S, Veniaminova NA, Wan K, Merchant JL, Hua X, Lei M. The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature. 482: 542-6. PMID 22327296 DOI: 10.1038/Nature10806  0.728
2012 Chen Y, Cao F, Wan B, Dou Y, Lei M. Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30. Cell Research. 22: 598-602. PMID 22231628 DOI: 10.1038/Cr.2012.9  0.695
2012 Yu EY, Sun J, Lei M, Lue NF. Analyses of Candida Cdc13 orthologues revealed a novel OB fold dimer arrangement, dimerization-assisted DNA binding, and substantial structural differences between Cdc13 and RPA70 Molecular and Cellular Biology. 32: 186-198. PMID 22025677 DOI: 10.1128/Mcb.05875-11  0.653
2011 Zeng Z, Min B, Huang J, Hong K, Yang Y, Collins K, Lei M. Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA. Proceedings of the National Academy of Sciences of the United States of America. 108: 20357-61. PMID 22143754 DOI: 10.1073/Pnas.1113624108  0.471
2011 Yen WF, Chico L, Lei M, Lue NF. Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA Proceedings of the National Academy of Sciences of the United States of America. 108: 20370-20375. PMID 21685334 DOI: 10.1073/Pnas.1017855108  0.496
2011 Chen Y, Wan B, Wang KC, Cao F, Yang Y, Protacio A, Dou Y, Chang HY, Lei M. Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Reports. 12: 797-803. PMID 21660059 DOI: 10.1038/Embor.2011.101  0.739
2011 Wang F, Lei M. Human telomere POT1-TPP1 complex and its role in telomerase activity regulation Methods in Molecular Biology (Clifton, N.J.). 735: 173-187. PMID 21461822 DOI: 10.1007/978-1-61779-092-8_17  0.36
2011 Wang KC, Yang YW, Liu B, Sanyal A, Corces-Zimmerman R, Chen Y, Lajoie BR, Protacio A, Flynn RA, Gupta RA, Wysocka J, Lei M, Dekker J, Helms JA, Chang HY. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature. 472: 120-4. PMID 21423168 DOI: 10.1038/Nature09819  0.309
2011 Chen Y, Rai R, Zhou ZR, Kanoh J, Ribeyre C, Yang Y, Zheng H, Damay P, Wang F, Tsujii H, Hiraoka Y, Shore D, Hu HY, Chang S, Lei M. A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms. Nature Structural & Molecular Biology. 18: 213-21. PMID 21217703 DOI: 10.1038/Nsmb.1974  0.465
2011 Sun J, Yang Y, Wan K, Mao N, Yu TY, Lin YC, Dezwaan DC, Freeman BC, Lin JJ, Lue NF, Lei M. Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α Cell Research. 21: 258-274. PMID 20877309 DOI: 10.1038/Cr.2010.138  0.63
2010 Cao F, Chen Y, Cierpicki T, Liu Y, Basrur V, Lei M, Dou Y. An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. Plos One. 5: e14102. PMID 21124902 DOI: 10.1371/Journal.Pone.0014102  0.332
2010 Wang F, Yang Y, Singh TR, Busygina V, Guo R, Wan K, Wang W, Sung P, Meetei AR, Lei M. Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex. Structure (London, England : 1993). 18: 1159-70. PMID 20826342 DOI: 10.1016/J.Str.2010.06.008  0.425
2010 Zeng Z, Wang W, Yang Y, Chen Y, Yang X, Diehl JA, Liu X, Lei M. Structural basis of selective ubiquitination of TRF1 by SCFFbx4. Developmental Cell. 18: 214-25. PMID 20159592 DOI: 10.1016/J.Devcel.2010.01.007  0.457
2009 Sun J, Yu EY, Yang Y, Confer LA, Sun SH, Wan K, Lue NF, Lei M. Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres Genes and Development. 23: 2900-2914. PMID 20008938 DOI: 10.1101/Gad.1851909  0.609
2009 Gardino AK, Villali J, Kivenson A, Lei M, Liu CF, Steindel P, Eisenmesser EZ, Labeikovsky W, Wolf-Watz M, Clarkson MW, Kern D. Transient non-native hydrogen bonds promote activation of a signaling protein. Cell. 139: 1109-18. PMID 20005804 DOI: 10.1016/J.Cell.2009.11.022  0.317
2009 Lei M, Velos J, Gardino A, Kivenson A, Karplus M, Kern D. Segmented transition pathway of the signaling protein nitrogen regulatory protein C. Journal of Molecular Biology. 392: 823-36. PMID 19576227 DOI: 10.1016/J.Jmb.2009.06.065  0.309
2009 Wang W, Yang Y, Gao Y, Xu Q, Wang F, Zhu S, Old W, Resing K, Ahn N, Lei M, Liu X. Structural and mechanistic insights into Mps1 kinase activation. Journal of Cellular and Molecular Medicine. 13: 1679-94. PMID 19120698 DOI: 10.1111/J.1582-4934.2008.00605.X  0.311
2008 Young Yu E, Wang F, Lei M, Lue NF. A proposed OB-fold with a protein-interaction surface in Candida albicans telomerase protein Est3 Nature Structural and Molecular Biology. 15: 985-989. PMID 19172753 DOI: 10.1038/Nsmb.1471  0.439
2008 Sowd G, Lei M, Opresko PL. Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase Nucleic Acids Research. 36: 4242-4256. PMID 18583366 DOI: 10.1093/Nar/Gkn385  0.452
2008 Chen Y, Yang Y, van Overbeek M, Donigian JR, Baciu P, de Lange T, Lei M. A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science (New York, N.Y.). 319: 1092-6. PMID 18202258 DOI: 10.1126/Science.1151804  0.456
2007 Wang F, Podell ER, Zaug AJ, Yang Y, Baciu P, Cech TR, Lei M. The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature. 445: 506-10. PMID 17237768 DOI: 10.1038/Nature05454  0.656
2006 Chen Y, Yang Y, Wang F, Wan K, Yamane K, Zhang Y, Lei M. Crystal structure of human histone lysine-specific demethylase 1 (LSD1). Proceedings of the National Academy of Sciences of the United States of America. 103: 13956-61. PMID 16956976 DOI: 10.1073/Pnas.0606381103  0.433
2005 Opresko PL, Mason PA, Podell ER, Lei M, Hickson ID, Cech TR, Bohr VA. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates. The Journal of Biological Chemistry. 280: 32069-80. PMID 16030011 DOI: 10.1074/Jbc.M505211200  0.618
2005 Lei M, Robinson MA, Harrison SC. The active conformation of the PAK1 kinase domain. Structure (London, England : 1993). 13: 769-78. PMID 15893667 DOI: 10.1016/J.Str.2005.03.007  0.328
2005 Lei M, Zaug AJ, Podell ER, Cech TR. Switching human telomerase on and off with hPOT1 protein in vitro. The Journal of Biological Chemistry. 280: 20449-56. PMID 15792951 DOI: 10.1074/Jbc.M502212200  0.65
2004 Lei M, Podell ER, Cech TR. Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection. Nature Structural & Molecular Biology. 11: 1223-9. PMID 15558049 DOI: 10.1038/Nsmb867  0.653
2003 Lei M, Podell ER, Baumann P, Cech TR. DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA. Nature. 426: 198-203. PMID 14614509 DOI: 10.1038/Nature02092  0.73
2002 Lei M, Baumann P, Cech TR. Cooperative binding of single-stranded telomeric DNA by the Pot1 protein of Schizosaccharomyces pombe. Biochemistry. 41: 14560-8. PMID 12463756 DOI: 10.1021/Bi026674Z  0.713
2002 Parrini MC, Lei M, Harrison SC, Mayer BJ. Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1. Molecular Cell. 9: 73-83. PMID 11804587 DOI: 10.1016/S1097-2765(01)00428-2  0.388
2001 Lowry WE, Huang J, Lei M, Rawlings D, Huang XY. Role of the PHTH Module in Protein Substrate Recognition by Bruton's Agammaglobulinemia Tyrosine Kinase Journal of Biological Chemistry. 276: 45276-45281. PMID 11577078 DOI: 10.1074/Jbc.M104449200  0.361
2000 Lei M, Lu W, Meng W, Parrini MC, Eck MJ, Mayer BJ, Harrison SC. Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell. 102: 387-97. PMID 10975528 DOI: 10.1016/S0092-8674(00)00043-X  0.394
1997 Merchant AM, Kawasaki Y, Chen Y, Lei M, Tye BK. A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae Molecular and Cellular Biology. 17: 3261-3271. PMID 9154825 DOI: 10.1128/Mcb.17.6.3261  0.376
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