Maria Blasco - Publications

Programa de Oncología Molecular Spanish National Cancer Centre, Madrid, Spain, Madrid, Comunidad de Madrid, Spain 

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Foronda M, Morgado-Palacin L, Gómez-López G, Domínguez O, Pisano DG, Blasco MA. Profiling of Sox4-dependent transcriptome in skin links tumour suppression and adult stem cell activation. Genomics Data. 6: 21-4. PMID 26697322 DOI: 10.1016/j.gdata.2015.07.030  0.48
2015 Calvete O, Martinez P, Garcia-Pavia P, Benitez-Buelga C, Paumard-Hernández B, Fernandez V, Dominguez F, Salas C, Romero-Laorden N, Garcia-Donas J, Carrillo J, Perona R, Triviño JC, Andrés R, Cano JM, ... ... Blasco MA, et al. A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families. Nature Communications. 6: 8383. PMID 26403419 DOI: 10.1038/ncomms9383  0.48
2015 Bär C, Huber N, Beier F, Blasco MA. Therapeutic effect of androgen therapy in a mouse model of aplastic anemia produced by short telomeres. Haematologica. 100: 1267-74. PMID 26206796 DOI: 10.3324/haematol.2015.129239  0.48
2015 Martínez P, Blasco MA. Replicating through telomeres: a means to an end. Trends in Biochemical Sciences. 40: 504-15. PMID 26188776 DOI: 10.1016/j.tibs.2015.06.003  0.48
2015 Scarola M, Comisso E, Pascolo R, Chiaradia R, Maria Marion R, Schneider C, Blasco MA, Schoeftner S, Benetti R. Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA. Nature Communications. 6: 7631. PMID 26158551 DOI: 10.1038/ncomms8631  0.48
2015 Povedano JM, Martinez P, Flores JM, Mulero F, Blasco MA. Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction. Cell Reports. PMID 26146081 DOI: 10.1016/j.celrep.2015.06.028  0.48
2015 Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, Keller PJ, Glover E, Richardson AL, Cowan J, Toland AE, Ravichandran K, Riethman H, Naber SP, Näär AM, ... Blasco MA, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nature Communications. 6: 7505. PMID 26106036 DOI: 10.1038/ncomms8505  0.48
2015 García-Beccaria M, Martínez P, Méndez-Pertuz M, Martínez S, Blanco-Aparicio C, Cañamero M, Mulero F, Ambrogio C, Flores JM, Megias D, Barbacid M, Pastor J, Blasco MA. Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage. Embo Molecular Medicine. PMID 25971796 DOI: 10.15252/emmm.201404497  0.48
2015 González-García MP, Pavelescu I, Canela A, Sevillano X, Leehy KA, Nelson AD, Ibañes M, Shippen DE, Blasco MA, Caño-Delgado AI. Single-cell telomere-length quantification couples telomere length to meristem activity and stem cell development in Arabidopsis. Cell Reports. 11: 977-89. PMID 25937286 DOI: 10.1016/j.celrep.2015.04.013  0.48
2015 Beier F, Martinez P, Blasco MA. Chronic replicative stress induced by CCl4 in TRF1 knockout mice recapitulates the origin of large liver cell changes. Journal of Hepatology. 63: 446-55. PMID 25819337 DOI: 10.1016/j.jhep.2015.03.022  0.48
2015 Bürkle A, Moreno-Villanueva M, Bernhard J, Blasco M, Zondag G, Hoeijmakers JH, Toussaint O, Grubeck-Loebenstein B, Mocchegiani E, Collino S, Gonos ES, Sikora E, Gradinaru D, Dollé M, Salmon M, et al. MARK-AGE biomarkers of ageing. Mechanisms of Ageing and Development. PMID 25818235 DOI: 10.1016/j.mad.2015.03.006  0.48
2014 Bär C, Bernardes de Jesus B, Serrano R, Tejera A, Ayuso E, Jimenez V, Formentini I, Bobadilla M, Mizrahi J, de Martino A, Gomez G, Pisano D, Mulero F, Wollert KC, Bosch F, ... Blasco MA, et al. Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction. Nature Communications. 5: 5863. PMID 25519492 DOI: 10.1038/ncomms6863  0.48
2014 Garrobo I, Marión RM, Domínguez O, Pisano DG, Blasco MA. Genome-wide analysis of in vivo TRF1 binding to chromatin restricts its location exclusively to telomeric repeats. Cell Cycle (Georgetown, Tex.). 13: 3742-9. PMID 25483083 DOI: 10.4161/15384101.2014.965044  0.48
2014 López de Silanes I, Graña O, De Bonis ML, Dominguez O, Pisano DG, Blasco MA. Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes. Nature Communications. 5: 4723. PMID 25182072 DOI: 10.1038/ncomms5723  0.48
2014 Foronda M, Martínez P, Schoeftner S, Gómez-López G, Schneider R, Flores JM, Pisano DG, Blasco MA. Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation. Cell Reports. 8: 487-500. PMID 25043184 DOI: 10.1016/j.celrep.2014.06.031  0.48
2014 De Bonis ML, Ortega S, Blasco MA. SIRT1 is necessary for proficient telomere elongation and genomic stability of induced pluripotent stem cells. Stem Cell Reports. 2: 690-706. PMID 24936455 DOI: 10.1016/j.stemcr.2014.03.002  0.48
2014 García-Beccaria M, Martínez P, Flores JM, Blasco MA. In vivo role of checkpoint kinase 2 in signaling telomere dysfunction. Aging Cell. 13: 810-6. PMID 24920220 DOI: 10.1111/acel.12237  0.48
2014 Martínez P, Ferrara-Romeo I, Flores JM, Blasco MA. Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 13: 656-68. PMID 24725274 DOI: 10.1111/acel.12221  0.48
2014 d'Alcontres MS, Palacios JA, Mejias D, Blasco MA. TopoIIα prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres. Cell Cycle (Georgetown, Tex.). 13: 1463-81. PMID 24626180 DOI: 10.4161/cc.28419  0.48
2013 Mondal AM, Horikawa I, Pine SR, Fujita K, Morgan KM, Vera E, Mazur SJ, Appella E, Vojtesek B, Blasco MA, Lane DP, Harris CC. p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes. The Journal of Clinical Investigation. 123: 5247-57. PMID 24231352 DOI: 10.1172/JCI70355  0.48
2013 Blasco MA. Fighting disease from the chromosome end. Epigenomics. 5: 483-5. PMID 24059795 DOI: 10.2217/epi.13.50  0.48
2013 Martinez-Delgado B, Gallardo M, Tanic M, Yanowsky K, Inglada-Perez L, Barroso A, Rodriguez-Pinilla M, Cañamero M, Blasco MA, Benitez J. Short telomeres are frequent in hereditary breast tumors and are associated with high tumor grade. Breast Cancer Research and Treatment. 141: 231-42. PMID 24036693 DOI: 10.1007/s10549-013-2696-6  0.48
2013 Bernardes de Jesus B, Blasco MA. Telomerase at the intersection of cancer and aging. Trends in Genetics : Tig. 29: 513-20. PMID 23876621 DOI: 10.1016/j.tig.2013.06.007  0.48
2013 Martínez P, Gómez-López G, García F, Mercken E, Mitchell S, Flores JM, de Cabo R, Blasco MA. RAP1 protects from obesity through its extratelomeric role regulating gene expression. Cell Reports. 3: 2059-74. PMID 23791526 DOI: 10.1016/j.celrep.2013.05.030  0.48
2013 López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 153: 1194-217. PMID 23746838 DOI: 10.1016/j.cell.2013.05.039  0.48
2013 Schneider RP, Garrobo I, Foronda M, Palacios JA, Marión RM, Flores I, Ortega S, Blasco MA. TRF1 is a stem cell marker and is essential for the generation of induced pluripotent stem cells. Nature Communications. 4: 1946. PMID 23735977 DOI: 10.1038/ncomms2946  0.48
2013 Ramsay AJ, Quesada V, Foronda M, Conde L, Martínez-Trillos A, Villamor N, Rodríguez D, Kwarciak A, Garabaya C, Gallardo M, López-Guerra M, López-Guillermo A, Puente XS, Blasco MA, Campo E, et al. POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia. Nature Genetics. 45: 526-30. PMID 23502782 DOI: 10.1038/ng.2584  0.48
2013 Vera E, Bernardes de Jesus B, Foronda M, Flores JM, Blasco MA. Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity. Plos One. 8: e53760. PMID 23349740 DOI: 10.1371/journal.pone.0053760  0.48
2013 Stout GJ, Blasco MA. Telomere length and telomerase activity impact the UV sensitivity syndrome xeroderma pigmentosum C. Cancer Research. 73: 1844-54. PMID 23288511 DOI: 10.1158/0008-5472.CAN-12-3125  0.48
2013 Tomás-Loba A, Bernardes de Jesus B, Mato JM, Blasco MA. A metabolic signature predicts biological age in mice. Aging Cell. 12: 93-101. PMID 23107558 DOI: 10.1111/acel.12025  0.48
2012 Bernardes de Jesus B, Blasco MA. Potential of telomerase activation in extending health span and longevity. Current Opinion in Cell Biology. 24: 739-43. PMID 23085234 DOI: 10.1016/  0.48
2012 Vera E, Bernardes de Jesus B, Foronda M, Flores JM, Blasco MA. The rate of increase of short telomeres predicts longevity in mammals. Cell Reports. 2: 732-7. PMID 23022483 DOI: 10.1016/j.celrep.2012.08.023  0.48
2012 Beier F, Foronda M, Martinez P, Blasco MA. Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita. Blood. 120: 2990-3000. PMID 22932806 DOI: 10.1182/blood-2012-03-418038  0.48
2012 Bernardes de Jesus B, Blasco MA. Assessing cell and organ senescence biomarkers. Circulation Research. 111: 97-109. PMID 22723221 DOI: 10.1161/CIRCRESAHA.111.247866  0.48
2012 Vera E, Blasco MA. Beyond average: potential for measurement of short telomeres. Aging. 4: 379-92. PMID 22683684  0.48
2012 Bernardes de Jesus B, Vera E, Schneeberger K, Tejera AM, Ayuso E, Bosch F, Blasco MA. Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer. Embo Molecular Medicine. 4: 691-704. PMID 22585399 DOI: 10.1002/emmm.201200245  0.48
2012 Martínez P, Flores JM, Blasco MA. 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response. The Journal of Cell Biology. 197: 283-300. PMID 22508511 DOI: 10.1083/jcb.201110124  0.48
2012 Ganuza M, Sáiz-Ladera C, Cañamero M, Gómez G, Schneider R, Blasco MA, Pisano D, Paramio JM, Santamaría D, Barbacid M. Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion. The Embo Journal. 31: 2498-510. PMID 22505032 DOI: 10.1038/emboj.2012.94  0.48
2012 Martinez-Delgado B, Yanowsky K, Inglada-Perez L, de la Hoya M, Caldes T, Vega A, Blanco A, Martin T, Gonzalez-Sarmiento R, Blasco M, Robledo M, Urioste M, Song H, Pharoah P, Benitez J. Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases. Journal of Medical Genetics. 49: 341-4. PMID 22493152 DOI: 10.1136/jmedgenet-2012-100807  0.48
2012 Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, Miriami E, Karczewski KJ, Hariharan M, Dewey FE, Cheng Y, Clark MJ, Im H, Habegger L, Balasubramanian S, ... ... Blasco MA, et al. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell. 148: 1293-307. PMID 22424236 DOI: 10.1016/j.cell.2012.02.009  0.48
2012 Remeseiro S, Cuadrado A, Carretero M, Martínez P, Drosopoulos WC, Cañamero M, Schildkraut CL, Blasco MA, Losada A. Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres. The Embo Journal. 31: 2076-89. PMID 22415365 DOI: 10.1038/emboj.2012.11  0.48
2012 Andoniadou CL, Gaston-Massuet C, Reddy R, Schneider RP, Blasco MA, Le Tissier P, Jacques TS, Pevny LH, Dattani MT, Martinez-Barbera JP. Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma. Acta Neuropathologica. 124: 259-71. PMID 22349813 DOI: 10.1007/s00401-012-0957-9  0.48
2012 Rocheteau P, Gayraud-Morel B, Siegl-Cachedenier I, Blasco MA, Tajbakhsh S. A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division. Cell. 148: 112-25. PMID 22265406 DOI: 10.1016/j.cell.2011.11.049  0.48
2011 Martin D, Pantoja C, Fernández Miñán A, Valdes-Quezada C, Moltó E, Matesanz F, Bogdanović O, de la Calle-Mustienes E, Domínguez O, Taher L, Furlan-Magaril M, Alcina A, Cañón S, Fedetz M, Blasco MA, et al. Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes. Nature Structural & Molecular Biology. 18: 708-14. PMID 21602820 DOI: 10.1038/nsmb.2059  0.48
2011 Bernardes de Jesus B, Schneeberger K, Vera E, Tejera A, Harley CB, Blasco MA. The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell. 10: 604-21. PMID 21426483 DOI: 10.1111/j.1474-9726.2011.00700.x  0.48
2011 Blasco MA, Serrano M, Fernandez-Capetillo O. Genomic instability in iPS: time for a break. The Embo Journal. 30: 991-3. PMID 21407252 DOI: 10.1038/emboj.2011.50  0.48
2011 Martínez P, Blasco MA. Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins. Nature Reviews. Cancer. 11: 161-76. PMID 21346783 DOI: 10.1038/nrc3025  0.48
2011 Bernardes de Jesus B, Blasco MA. Aging by telomere loss can be reversed. Cell Stem Cell. 8: 3-4. PMID 21211774 DOI: 10.1016/j.stem.2010.12.013  0.48
2011 Donate LE, Blasco MA. Telomeres in cancer and ageing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 76-84. PMID 21115533 DOI: 10.1098/rstb.2010.0291  0.48
2011 Harley CB, Liu W, Blasco M, Vera E, Andrews WH, Briggs LA, Raffaele JM. A natural product telomerase activator as part of a health maintenance program. Rejuvenation Research. 14: 45-56. PMID 20822369 DOI: 10.1089/rej.2010.1085  0.48
2010 Palacios JA, Herranz D, De Bonis ML, Velasco S, Serrano M, Blasco MA. SIRT1 contributes to telomere maintenance and augments global homologous recombination. The Journal of Cell Biology. 191: 1299-313. PMID 21187328 DOI: 10.1083/jcb.201005160  0.48
2010 Badie S, Escandell JM, Bouwman P, Carlos AR, Thanasoula M, Gallardo MM, Suram A, Jaco I, Benitez J, Herbig U, Blasco MA, Jonkers J, Tarsounas M. BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping. Nature Structural & Molecular Biology. 17: 1461-9. PMID 21076401 DOI: 10.1038/nsmb.1943  0.48
2010 López de Silanes I, Stagno d'Alcontres M, Blasco MA. TERRA transcripts are bound by a complex array of RNA-binding proteins. Nature Communications. 1: 33. PMID 20975687 DOI: 10.1038/ncomms1032  0.48
2010 Flores I, Blasco MA. The role of telomeres and telomerase in stem cell aging. Febs Letters. 584: 3826-30. PMID 20674573 DOI: 10.1016/j.febslet.2010.07.042  0.48
2010 Martinez P, Thanasoula M, Carlos AR, Gómez-López G, Tejera AM, Schoeftner S, Dominguez O, Pisano DG, Tarsounas M, Blasco MA. Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites. Nature Cell Biology. 12: 768-80. PMID 20622869 DOI: 10.1038/ncb2081  0.48
2010 Martínez P, Blasco MA. Role of shelterin in cancer and aging. Aging Cell. 9: 653-66. PMID 20569239 DOI: 10.1111/j.1474-9726.2010.00596.x  0.48
2010 Tejera AM, Stagno d'Alcontres M, Thanasoula M, Marion RM, Martinez P, Liao C, Flores JM, Tarsounas M, Blasco MA. TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice. Developmental Cell. 18: 775-89. PMID 20493811 DOI: 10.1016/j.devcel.2010.03.011  0.48
2010 Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, et al. Impact papers on aging in 2009. Aging. 2: 111-21. PMID 20351400 DOI: v2/n3/full/100132.html  0.48
2010 Varela E, Blasco MA. 2009 Nobel Prize in Physiology or Medicine: Telomeres and telomerase Oncogene. 29: 1561-1565. PMID 20237481 DOI: 10.1038/onc.2010.15  0.48
2010 Thanasoula M, Escandell JM, Martinez P, Badie S, Muñoz P, Blasco MA, Tarsounas M. p53 prevents entry into mitosis with uncapped telomeres. Current Biology : Cb. 20: 521-6. PMID 20226664 DOI: 10.1016/j.cub.2010.01.046  0.48
2010 McNees CJ, Tejera AM, Martínez P, Murga M, Mulero F, Fernandez-Capetillo O, Blasco MA. ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase. The Journal of Cell Biology. 188: 639-52. PMID 20212315 DOI: 10.1083/jcb.200908136  0.48
2010 Marión RM, Blasco MA. Telomere rejuvenation during nuclear reprogramming. Current Opinion in Genetics & Development. 20: 190-6. PMID 20176474 DOI: 10.1016/j.gde.2010.01.005  0.48
2010 Schoeftner S, Blasco MA. Chromatin regulation and non-coding RNAs at mammalian telomeres. Seminars in Cell & Developmental Biology. 21: 186-93. PMID 19815087 DOI: 10.1016/j.semcdb.2009.09.015  0.48
2010 Blasco MA. The Ying and Yang of telomeres: Cancer and aging | El Ying y el Yang de los telómeros: Cáncer y envejecimiento Anales De La Real Academia Nacional De Farmacia. 76: 105-118.  0.48
2009 Ferrón SR, Marqués-Torrejón MA, Mira H, Flores I, Taylor K, Blasco MA, Fariñas I. Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14394-407. PMID 19923274 DOI: 10.1523/JNEUROSCI.3836-09.2009  0.48
2009 Schoeftner S, Blanco R, Lopez de Silanes I, Muñoz P, Gómez-López G, Flores JM, Blasco MA. Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations. Proceedings of the National Academy of Sciences of the United States of America. 106: 19393-8. PMID 19887628 DOI: 10.1073/pnas.0909265106  0.48
2009 Martínez P, Thanasoula M, Muñoz P, Liao C, Tejera A, McNees C, Flores JM, Fernández-Capetillo O, Tarsounas M, Blasco MA. Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes & Development. 23: 2060-75. PMID 19679647 DOI: 10.1101/gad.543509  0.48
2009 Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, Fernandez-Capetillo O, Serrano M, Blasco MA. A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature. 460: 1149-53. PMID 19668189 DOI: 10.1038/nature08287  0.48
2009 Li H, Collado M, Villasante A, Strati K, Ortega S, Cañamero M, Blasco MA, Serrano M. The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature. 460: 1136-9. PMID 19668188 DOI: 10.1038/nature08290  0.48
2009 Schoeftner S, Blasco MA. A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs. The Embo Journal. 28: 2323-36. PMID 19629032 DOI: 10.1038/emboj.2009.197  0.48
2009 Sebastián C, Herrero C, Serra M, Lloberas J, Blasco MA, Celada A. Telomere shortening and oxidative stress in aged macrophages results in impaired STAT5a phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 183: 2356-64. PMID 19605693 DOI: 10.4049/jimmunol.0901131  0.48
2009 Cipriano C, Tesei S, Malavolta M, Giacconi R, Muti E, Costarelli L, Piacenza F, Pierpaoli S, Galeazzi R, Blasco M, Vera E, Canela A, Lattanzio F, Mocchegiani E. Accumulation of cells with short telomeres is associated with impaired zinc homeostasis and inflammation in old hypertensive participants. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 745-51. PMID 19359441 DOI: 10.1093/gerona/glp048  0.48
2009 Flores I, Blasco MA. A p53-dependent response limits epidermal stem cell functionality and organismal size in mice with short telomeres Plos One. 4. PMID 19295915 DOI: 10.1371/journal.pone.0004934  0.48
2009 Garcia-Lavandeira M, Quereda V, Flores I, Saez C, Diaz-Rodriguez E, Japon MA, Ryan AK, Blasco MA, Dieguez C, Malumbres M, Alvarez CV. A GRFa2/Prop1/Stem (GPS) cell niche in the pituitary Plos One. 4. PMID 19283075 DOI: 10.1371/journal.pone.0004815  0.48
2009 Stout GJ, Blasco MA. Genetic dissection of the mechanisms underlying telomere-associated diseases: Impact of the TRF2 telomeric protein on mouse epidermal stem cells Dmm Disease Models and Mechanisms. 2: 139-156. PMID 19259387 DOI: 10.1242/dmm.002121  0.48
2009 Marion RM, Strati K, Li H, Tejera A, Schoeftner S, Ortega S, Serrano M, Blasco MA. Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells Cell Stem Cell. 4: 141-154. PMID 19200803 DOI: 10.1016/j.stem.2008.12.010  0.48
2009 Bouffler SD, Finnon P, Blasco MA, Ainsbury E. A possible role for telomerase RNA and telomere length in global mitotic recombination Cytogenetic and Genome Research. 122: 292-296. PMID 19188698 DOI: 10.1159/000167815  0.48
2009 Muñoz P, Blanco R, De Carcer G, Schoeftner S, Benetti R, Flores JM, Malumbres M, Blasco MA. TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis Molecular and Cellular Biology. 29: 1608-1625. PMID 19124610 DOI: 10.1128/MCB.01339-08  0.48
2009 Martinez P, Siegl-Cachedenier I, Flores JM, Blasco MA. MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres Aging Cell. 8: 2-17. PMID 18986375 DOI: 10.1111/j.1474-9726.2008.00441.x  0.48
2009 Cipriano C, Tesei S, Malavolta M, Marcellini F, Giuli C, Papa R, Lattanzio F, Blasco M, Mocchegiani E. Possible relationship between cognitive impairment and telomere length | Possibile relazione tra decadimento cognitivo e lunghezza dei telomeri Giornale Di Gerontologia. 57: 184-188.  0.48
2008 Tomás-Loba A, Flores I, Fernández-Marcos PJ, Cayuela ML, Maraver A, Tejera A, Borrás C, Matheu A, Klatt P, Flores JM, Viña J, Serrano M, Blasco MA. Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice Cell. 135: 609-622. PMID 19013273 DOI: 10.1016/j.cell.2008.09.034  0.48
2008 Benetti R, Schoeftner S, Muñoz P, Blasco MA. Role of TRF2 in the assembly of telomeric chromatin Cell Cycle. 7: 3461-3468. PMID 18971622  0.48
2008 Benetti R, Gonzalo S, Jaco I, Muñoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA. A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nature Structural & Molecular Biology. 15: 998. PMID 18769471 DOI: 10.1038/nsmb0908-998b  0.48
2008 Vera E, Canela A, Fraga MF, Esteller M, Blasco MA. Epigenetic regulation of telomeres in human cancer Oncogene. 27: 6817-6833. PMID 18762811 DOI: 10.1038/onc.2008.289  0.48
2008 Pérez-Rivero G, Ruiz-Torres MP, Díez-Marqués ML, Canela A, López-Novoa JM, Rodríguez-Puyol M, Blasco MA, Rodríguez-Puyol D. Telomerase deficiency promotes oxidative stress by reducing catalase activity Free Radical Biology and Medicine. 45: 1243-1251. PMID 18718525 DOI: 10.1016/j.freeradbiomed.2008.07.017  0.48
2008 Jaco I, Canela A, Vera E, Blasco MA. Centromere mitotic recombination in mammalian cells Journal of Cell Biology. 181: 885-892. PMID 18541703 DOI: 10.1083/jcb.200803042  0.48
2008 Mocchegiani E, Malavolta M, Giacconi R, Cipriano C, Costarelli L, Muti E, Tesei S, Giuli C, Papa R, Marcellini F, Mariani E, Rink L, Herbein G, Fulop T, Monti D, ... ... Blasco M, et al. Zinc, metallothioneins, longevity: Effect of zinc supplementation on antioxidant response: A zincage study Rejuvenation Research. 11: 419-423. PMID 18442325 DOI: 10.1089/rej.2008.0686  0.48
2008 Espada J, Varela I, Flores I, Ugalde AP, Cadiñanos J, Pendás AM, Stewart CL, Tryggvason K, Blasco MA, Freije JMP, López-Otín C. Nuclear envelope defects cause stem cell dysfunction in premature-aging mice Journal of Cell Biology. 181: 27-35. PMID 18378773 DOI: 10.1083/jcb.200801096  0.48
2008 Blasco M, Domeño C, Nerín C. Lichens biomonitoring as feasible methodology to assess air pollution in natural ecosystems: Combined study of quantitative PAHs analyses and lichen biodiversity in the Pyrenees Mountains Analytical and Bioanalytical Chemistry. 391: 759-771. PMID 18335215 DOI: 10.1007/s00216-008-1890-6  0.48
2008 Benetti R, Gonzalo S, Jaco I, Muñoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA. A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nature Structural & Molecular Biology. 15: 268-79. PMID 18311151 DOI: 10.1038/nsmb.1399  0.48
2008 Flores I, Canela A, Vera E, Tejera A, Cotsarelis G, Blasco MA. The longest telomeres: A general signature of adult stem cell compartments Genes and Development. 22: 654-667. PMID 18283121 DOI: 10.1101/gad.451008  0.48
2008 Schoeftner S, Blasco MA. Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II Nature Cell Biology. 10: 228-236. PMID 18157120 DOI: 10.1038/ncb1685  0.48
2008 Blasco MAC. Differential diagnosis of joint disease of the distal interphalangeal joints of hand | Diagnóstico diferencial de la artropatía de las articulaciones interfalángicas distales de las manos Seminarios De La Fundacion Espanola De Reumatologia. 9: 43-58. DOI: 10.1016/S1577-3566(08)73629-7  0.48
2008 Blasco MA. Telomere binding proteins and disease Telomeres and Telomerase in Ageing, Disease, and Cancer: Molecular Mechanisms of Adult Stem Cell Ageing. 229-244. DOI: 10.1007/978-3-540-73709-4_12  0.48
2007 Liu L, Bailey SM, Okuka M, Muñoz P, Li C, Zhou L, Wu C, Czerwiec E, Sandler L, Seyfang A, Blasco MA, Keefe DL. Telomere lengthening early in development. Nature Cell Biology. 9: 1436-41. PMID 17982445 DOI: 10.1038/ncb1664  0.48
2007 Siegl-Cachedenier I, Flores I, Klatt P, Blasco MA. Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres Journal of Cell Biology. 179: 277-290. PMID 17954610 DOI: 10.1083/jcb.200704141  0.48
2007 Salvati E, Leonetti C, Rizzo A, Scarsella M, Mottolese M, Galati R, Sperduti I, Stevens MFG, D'Incalci M, Blasco M, Chiorino G, Bauwens S, Horard B, Gilson E, Stoppacciaro A, et al. Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect Journal of Clinical Investigation. 117: 3236-3247. PMID 17932567 DOI: 10.1172/JCI32461  0.48
2007 Blasco MA. Telomere length, stem cells and aging Nature Chemical Biology. 3: 640-649. PMID 17876321 DOI: 10.1038/nchembio.2007.38  0.48
2000 Chen JL, Blasco MA, Greider CW. Secondary structure of vertebrate telomerase RNA. Cell. 100: 503-14. PMID 10721988  0.48
1998 Lee HW, Blasco MA, Gottlieb GJ, Horner JW, Greider CW, DePinho RA. Essential role of mouse telomerase in highly proliferative organs. Nature. 392: 569-74. PMID 9560153 DOI: 10.1038/33345  0.48
1998 Hinkley CS, Blasco MA, Funk WD, Feng J, Villeponteau B, Greider CW, Herr W. The mouse telomerase RNA 5"-end lies just upstream of the telomerase template sequence. Nucleic Acids Research. 26: 532-6. PMID 9421511 DOI: 10.1093/nar/26.2.532  0.48
1997 Blasco MA, Lee HW, Rizen M, Hanahan D, DePinho R, Greider CW. Mouse models for the study of telomerase. Ciba Foundation Symposium. 211: 160-70; discussion 1. PMID 9524757  0.48
1997 Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell. 91: 25-34. PMID 9335332 DOI: 10.1016/S0092-8674(01)80006-4  0.48
1996 Blasco MA, Rizen M, Greider CW, Hanahan D. Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis. Nature Genetics. 12: 200-4. PMID 8563761 DOI: 10.1038/ng0296-200  0.48
1995 Blasco MA, Funk W, Villeponteau B, Greider CW. Functional characterization and developmental regulation of mouse telomerase RNA. Science (New York, N.Y.). 269: 1267-70. PMID 7544492  0.48
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