Alan K. Meeker, Ph.D. - Publications

Affiliations: 
2001 Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology, Cell Biology

174 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mori JO, Platz EA, Lu J, Brame A, Han M, Joshu CE, De Marzo AM, Meeker AK, Heaphy CM. Longer prostate stromal cell telomere length is associated with increased risk of death from other cancers. Frontiers in Medicine. 11: 1390769. PMID 38895181 DOI: 10.3389/fmed.2024.1390769  0.449
2024 Graham MK, Xu B, Davis C, Meeker AK, Heaphy CM, Yegnasubramanian S, Dyer MA, Zeineldin M. The TERT promoter is polycomb-repressed in neuroblastoma cells with long telomeres. Cancer Research Communications. PMID 38837897 DOI: 10.1158/2767-9764.CRC-22-0287  0.762
2024 Caramella-Pereira F, Zheng Q, Hicks JL, Roy S, Jones T, Pomper M, Antony L, Meeker AK, Yegnasubramanian S, De Marzo AM, Brennen WN. Overexpression of Fibroblast Activation Protein (FAP) in stroma of proliferative inflammatory atrophy (PIA) and primary adenocarcinoma of the prostate. Medrxiv : the Preprint Server For Health Sciences. PMID 38633791 DOI: 10.1101/2024.04.04.24305338  0.638
2023 Pinto LM, Pailas A, Bondarchenko M, Sharma AB, Neumann K, Rizzo AJ, Jeanty C, Nicot N, Racca C, Graham MK, Naughton C, Liu Y, Chen CL, Meakin PJ, Gilbert N, ... ... Meeker AK, et al. DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks. Nucleic Acids Research. PMID 38038252 DOI: 10.1093/nar/gkad1141  0.699
2023 Mori JO, Elhussin I, Brennen WN, Graham MK, Lotan TL, Yates CC, De Marzo AM, Denmeade SR, Yegnasubramanian S, Nelson WG, Denis GV, Platz EA, Meeker AK, Heaphy CM. Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer. Nature Reviews. Urology. PMID 37907729 DOI: 10.1038/s41585-023-00827-x  0.82
2022 Heaphy CM, Joshu CE, Barber JR, Davis C, Lu J, Zarinshenas R, Giovannucci E, Mucci LA, Stampfer MJ, Han M, De Marzo AM, Lotan TL, Platz EA, Meeker AK. The prostate tissue-based telomere biomarker as a prognostic tool for metastasis and death from prostate cancer after prostatectomy. The Journal of Pathology. Clinical Research. PMID 35836303 DOI: 10.1002/cjp2.288  0.441
2021 Li QK, Chen J, Hu Y, Höti N, Lih TM, Thomas SN, Chen L, Roy S, Meeker A, Shah P, Chen L, Bova GS, Zhang B, Zhang H. Proteomic characterization of primary and metastatic prostate cancer reveals reduced proteinase activity in aggressive tumors. Scientific Reports. 11: 18936. PMID 34556748 DOI: 10.1038/s41598-021-98410-0  0.335
2021 Zhan D, Ma D, Wei S, Lal B, Fu Y, Eberhart C, Laterra J, Ying M, Li Y, Meeker A, Lopez-Bertoni H, Xia S. Monoallelic IDH1 R132H mutation mediates glioma cell response to anti-cancer therapies via induction of senescence. Molecular Cancer Research : McR. PMID 34348994 DOI: 10.1158/1541-7786.MCR-21-0284  0.303
2021 Shrestha E, Coulter JB, Guzman W, Ozbek B, Hess MM, Mummert L, Ernst SE, Maynard JP, Meeker AK, Heaphy CM, Haffner MC, De Marzo AM, Sfanos KS. Oncogenic gene fusions in nonneoplastic precursors as evidence that bacterial infection can initiate prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34341114 DOI: 10.1073/pnas.2018976118  0.404
2021 Zhu Y, Dalrymple SL, Coleman I, Zheng SL, Xu J, Hooper JE, Antonarakis ES, De Marzo AM, Meeker AK, Nelson PS, Isaacs WB, Denmeade SR, Luo J, Brennen WN, Isaacs JT. Correction: Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors. Oncogene. PMID 33958727 DOI: 10.1038/s41388-021-01805-6  0.506
2021 Brennen WN, Zhu Y, Coleman IM, Dalrymple SL, Antony L, Patel RA, Hanratty B, Chikarmane R, Meeker AK, Zheng SL, Hooper JE, Luo J, De Marzo AM, Corey E, Xu J, et al. Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer. Jci Insight. PMID 33724955 DOI: 10.1172/jci.insight.146827  0.696
2021 Zhu Y, Dalrymple SL, Coleman I, Zheng SL, Xu J, Hooper JE, Antonarakis ES, De Marzo AM, Meeker AK, Nelson PS, Isaacs WB, Denmeade SR, Luo J, Brennen WN, Isaacs JT. Correction to: Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors. Oncogene. PMID 33564077 DOI: 10.1038/s41388-021-01640-9  0.506
2020 Joshu CE, Heaphy CM, Barber JR, Lu J, Zarinshenas R, Davis C, Han M, Lotan TL, Sfanos KS, De Marzo AM, Meeker AK, Platz EA. Obesity is associated with shorter telomere length in prostate stromal cells in men with aggressive prostate cancer. Cancer Prevention Research (Philadelphia, Pa.). PMID 33355185 DOI: 10.1158/1940-6207.CAPR-20-0250  0.323
2020 Zhu Y, Dalrymple SL, Coleman I, Zheng SL, Xu J, Hooper JE, Antonarakis ES, De Marzo AM, Meeker AK, Nelson PS, Isaacs WB, Denmeade SR, Luo J, Brennen WN, Isaacs JT. Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors. Oncogene. PMID 32989253 DOI: 10.1038/s41388-020-01479-6  0.473
2020 Low JY, Brennen WN, Meeker AK, Ikonen E, Simons BW, Laiho M. Stromal CAVIN1 controls prostate cancer microenvironment and metastasis by modulating lipid distribution and inflammatory signaling. Molecular Cancer Research : McR. PMID 32493699 DOI: 10.1158/1541-7786.Mcr-20-0364  0.472
2020 Esopi D, Graham MK, Brosnan-Cashman JA, Meyers J, Vaghasia A, Gupta A, Kumar B, Haffner MC, Heaphy CM, De Marzo AM, Meeker AK, Nelson WG, Wheelan SJ, Yegnasubramanian S. Pervasive promoter hypermethylation of silenced TERT alleles in human cancers. Cellular Oncology (Dordrecht). PMID 32468444 DOI: 10.1007/S13402-020-00531-7  0.789
2020 Heaphy CM, Haffner MC, Graham MK, Lim D, Davis C, Corey E, Epstein JI, Eisenberger MA, Wang H, De Marzo AM, Meeker AK, Lotan TL. Telomere lengths differ significantly between small cell neuroendocrine prostate carcinoma and adenocarcinoma of the prostate. Human Pathology. PMID 32389660 DOI: 10.1016/J.Humpath.2020.04.014  0.775
2020 Pichinuk E, Chalik M, Benhar I, Ginat-Koton R, Ziv R, Smorodinsky NI, Haran G, Garbar C, Bensussan A, Meeker A, Guillaume T, Rubinstein DB, Wreschner DH. In vivo anti-MUC1 tumor activity and sequences of high-affinity anti-MUC1-SEA antibodies. Cancer Immunology, Immunotherapy : Cii. 69: 1337-1352. PMID 32219500 DOI: 10.1007/S00262-020-02547-2  0.376
2020 Heaphy CM, Joshu CE, Barber JR, Davis C, Zarinshenas R, De Marzo AM, Lotan TL, Sfanos KS, Meeker AK, Platz EA. Racial difference in prostate cancer cell telomere lengths in men with higher-grade prostate cancer: a clue to the racial disparity in prostate cancer outcomes. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 31915143 DOI: 10.1158/1055-9965.Epi-19-1462  0.517
2019 Graham MK, Kim J, Da J, Brosnan-Cashman JA, Rizzo A, Baena Del Valle JA, Chia L, Rubenstein M, Davis C, Zheng Q, Cope L, Considine M, Haffner MC, De Marzo AM, Meeker AK, et al. Functional loss of ATRX and TERC activates Alternative Lengthening of Telomeres (ALT) in LAPC4 prostate cancer cells. Molecular Cancer Research : McR. PMID 31611308 DOI: 10.1158/1541-7786.Mcr-19-0654  0.809
2019 Tomasetti C, Poling J, Roberts NJ, London NR, Pittman ME, Haffner MC, Rizzo A, Baras A, Karim B, Kim A, Heaphy CM, Meeker AK, Hruban RH, Iacobuzio-Donahue CA, Vogelstein B. Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence. Proceedings of the National Academy of Sciences of the United States of America. PMID 31548407 DOI: 10.1073/Pnas.1905722116  0.34
2019 Gorbounov M, Carleton NM, Asch-Kendrick RJ, Xian L, Rooper L, Chia L, Cimino-Mathews A, Cope L, Meeker A, Stearns V, Veltri RW, Bae YK, Resar LMS. High mobility group A1 (HMGA1) protein and gene expression correlate with ER-negativity and poor outcomes in breast cancer. Breast Cancer Research and Treatment. PMID 31531802 DOI: 10.1007/S10549-019-05419-1  0.358
2019 Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, ... ... Meeker A, et al. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Science Translational Medicine. 11. PMID 30760578 DOI: 10.1126/Scitranslmed.Aaq1427  0.331
2019 Mullan B, Qin T, Siada R, Ravindran R, Garcia T, Muruganand A, Harris M, Danussi C, Brosnan-Cashman J, Pratt D, Zhao X, Rehemtulla A, Sartor M, Venneti S, Meeker A, et al. GENE-17. ATRX LOSS IN GLIOMA RESULTS IN EPIGENETIC DYSREGULATION OF THE G2/M CHECKPOINT AND SENSITIVITY TO ATM INHIBITION Neuro-Oncology. 21: vi101-vi101. DOI: 10.1093/Neuonc/Noz175.419  0.377
2018 Marrone MT, Joshu CE, Peskoe SB, De Marzo AM, Heaphy CM, Lupold SE, Meeker AK, Platz EA. Adding the Team into T1 Translational Research: A Case Study of Multidisciplinary Team Science in the Evaluation of Biomarkers of Prostate Cancer Risk and Prognosis. Clinical Chemistry. PMID 30518666 DOI: 10.1373/Clinchem.2018.293365  0.691
2018 Krueger TE, Thorek DLJ, Meeker AK, Isaacs JT, Brennen WN. Tumor-infiltrating mesenchymal stem cells: Drivers of the immunosuppressive tumor microenvironment in prostate cancer? The Prostate. PMID 30488530 DOI: 10.1002/Pros.23738  0.53
2018 Brosnan-Cashman JA, Yuan M, Graham MK, Rizzo AJ, Myers KM, Davis C, Zhang R, Esopi DM, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner. Plos One. 13: e0204159. PMID 30226859 DOI: 10.1371/Journal.Pone.0204159  0.768
2018 Trabzonlu L, Kulac I, Zheng Q, Hicks JL, Haffner MC, Nelson WG, Sfanos KS, Ertunc O, Lotan TL, Heaphy CM, Meeker AK, Yegnasubramanian S, De Marzo AM. Molecular Pathology of High-Grade Prostatic Intraepithelial Neoplasia: Challenges and Opportunities. Cold Spring Harbor Perspectives in Medicine. PMID 30082453 DOI: 10.1101/Cshperspect.A030403  0.645
2018 Boudadi K, Suzman DL, Anagnostou V, Fu W, Luber B, Wang H, Niknafs N, White JR, Silberstein JL, Sullivan R, Dowling D, Harb R, Nirschl TR, Veeneman BA, Tomlins SA, ... ... Meeker AK, et al. Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer. Oncotarget. 9: 28561-28571. PMID 29983880 DOI: 10.18632/Oncotarget.25564  0.466
2018 Diplas BH, He X, Brosnan-Cashman JA, Liu H, Chen LH, Wang Z, Moure CJ, Killela PJ, Loriaux DB, Lipp ES, Greer PK, Yang R, Rizzo AJ, Rodriguez FJ, Friedman AH, ... ... Meeker AK, et al. The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma. Nature Communications. 9: 2087. PMID 29802247 DOI: 10.1038/S41467-018-04448-6  0.31
2018 Bell WR, Meeker AK, Rizzo A, Rajpara S, Rosenthal IM, Flores Bellver M, Aparicio Domingo S, Zhong X, Barber JR, Joshu CE, Canto-Soler MV, Eberhart CG, Heaphy CM. A UNIQUE TELOMERE DNA EXPANSION PHENOTYPE IN HUMAN RETINAL ROD PHOTORECEPTORS ASSOCIATED WITH AGING AND DISEASE. Brain Pathology (Zurich, Switzerland). PMID 29668072 DOI: 10.1111/Bpa.12618  0.345
2018 Meeker AK. Cancer telomeres and white crows. American Journal of Clinical and Experimental Urology. 6: 93-100. PMID 29666837  0.389
2018 Haffner MC, Guner G, Taheri D, Netto GJ, Palsgrove DN, Zheng Q, Guedes LB, Kim K, Tsai H, Esopi DM, Lotan T, Sharma R, Meeker AK, Chinnaiyan AM, Nelson WG, et al. Comprehensive evaluation of PD-L1 expression in primary and metastatic prostate cancer. The American Journal of Pathology. PMID 29577933 DOI: 10.1016/J.Ajpath.2018.02.014  0.598
2018 Brosnan-Cashman JA, Graham MK, Rizzo AJ, Myers K, Zhang R, Göger E, Zarinshenas R, Davis C, Yuan M, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract B14: Establishment and characterization of in vitro models of alternative lengthening of telomeres (ALT) in pediatric high-grade glioma Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-B14  0.769
2018 Duffield AS, Ascierto ML, Anders RA, Taube JM, McMiller TL, Engle EL, Meeker AK, Berger AE, Pardoll DM, Ambinder RF, Topalian SL. Abstract 4750: The immunosuppressive tumor microenvironment (TME) in nasopharyngeal carcinoma: implications for immunotherapy Cancer Research. 78: 4750-4750. DOI: 10.1158/1538-7445.Am2018-4750  0.334
2018 Brosnan-Cashman JA, Heaphy CM, Meeker AK. Abstract 1467: Isolation and characterization of cancer cells containing ultrabright telomere DNA foci associated with alternative lengthening of telomeres (ALT): A novel utility for combined telomere-specific FISH and flow cytometry (Flow FISH) Cancer Research. 78: 1467-1467. DOI: 10.1158/1538-7445.Am2018-1467  0.492
2017 Ojalvo LS, Thompson ED, Wang TL, Meeker AK, Shih IM, Fader AN, Cimino-Mathews AM, Emens LA. Tumor-Associated Macrophages and the Tumor Immune Microenvironment of Primary and Recurrent Epithelial Ovarian Cancer (EOC). Human Pathology. PMID 29288043 DOI: 10.1016/J.Humpath.2017.12.010  0.336
2017 Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Mucci LA, Giovannucci EL, Stampfer MJ, Yoon G, Lee TK, Hicks JL, De Marzo AM, Meeker AK, Platz EA. Current or recent smoking is associated with more variable telomere length in prostate stromal cells and prostate cancer cells. The Prostate. PMID 29164645 DOI: 10.1002/Pros.23462  0.482
2017 Muroyama Y, Nirschl TR, Kochel CM, Lopez-Bujanda Z, Theodros D, Mao W, Carrera-Haro MA, Ghasemzadeh A, Marciscano AE, Velarde E, Tam AJ, Thoburn CJ, Uddin M, Meeker AK, Anders RA, et al. Stereotactic radiotherapy increases functionally suppressive regulatory T cells in the tumor microenvironment. Cancer Immunology Research. PMID 28970196 DOI: 10.1158/2326-6066.Cir-17-0040  0.302
2017 Baena-Del Valle JA, Zheng Q, Esopi DM, Rubenstein M, Hubbard GK, Moncaliano MC, Hruszkewycz A, Vaghasia A, Yegnasubramanian S, Wheelan SJ, Meeker AK, Heaphy CM, Graham MK, De Marzo AM. MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer. The Journal of Pathology. PMID 28888037 DOI: 10.1002/Path.4980  0.827
2017 Sharifi-Sanjani M, Meeker AK, Mourkioti F. Evaluation of telomere length in human cardiac tissues using cardiac quantitative FISH. Nature Protocols. 12: 1855-1870. PMID 28817123 DOI: 10.1038/Nprot.2017.082  0.32
2017 Graham MK, Meeker A. Telomeres and telomerase in prostate cancer development and therapy. Nature Reviews. Urology. PMID 28675175 DOI: 10.1038/Nrurol.2017.104  0.808
2017 Brennen WN, Zhang B, Kulac I, Kisteman LN, Antony L, Wang H, Meeker AK, De Marzo AM, Garraway IP, Denmeade SR, Isaacs JT. Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate. Oncotarget. PMID 28493842 DOI: 10.18632/Oncotarget.17362  0.487
2017 Jinawath N, Shiao MS, Norris A, Murphy K, Klein AP, Yonescu R, Iacobuzio-Donahue C, Meeker A, Jinawath A, Yeo CJ, Eshleman JR, Hruban RH, Brody JR, Griffin CA, Harada S. Alterations of type II classical cadherin Cadherin-10 (CDH10) is associated with pancreatic ductal adenocarcinomas. Genes, Chromosomes & Cancer. PMID 28124395 DOI: 10.1002/Gcc.22447  0.35
2017 Koschmann C, Nunez FJ, Mendez F, Brosnan-Cashman JA, Meeker AK, Lowenstein PR, Castro MG. Mutated Chromatin Regulatory Factors as Tumor Drivers in Cancer. Cancer Research. PMID 28062403 DOI: 10.1158/0008-5472.Can-16-2301  0.4
2017 Peskoe SB, Barber JR, Zheng Q, Meeker AK, De Marzo AM, Platz EA, Lupold SE. Differential long-term stability of microRNAs and RNU6B snRNA in 12-20 year old archived formalin-fixed paraffin-embedded specimens. Bmc Cancer. 17: 32. PMID 28061773 DOI: 10.1186/S12885-016-3008-4  0.613
2017 Boudadi K, Suzman DL, Luber B, Wang H, Silberstein J, Sullivan R, Dowling D, Harb R, Nirschl T, Dittamore RV, Carducci MA, Eisenberger MA, Haffner M, Meeker A, Eshleman JR, et al. Phase 2 biomarker-driven study of ipilimumab plus nivolumab (Ipi/Nivo) for ARV7-positive metastatic castrate-resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 35: 5035-5035. DOI: 10.1200/Jco.2017.35.15_Suppl.5035  0.401
2017 Ojalvo LS, Thompson ED, Wang T, Meeker AK, Shih I, Fader AN, Cimino-Mathews A, Emens LA. Abstract 3991: Profiling the immune tumor microenvironment in primary and recurrent epithelial ovarian cancer Cancer Research. 77: 3991-3991. DOI: 10.1158/1538-7445.Am2017-3991  0.374
2017 Barry W, Heaphy C, Meeker A. Abstract 3470: The promyelocytic leukemia (PML) protein modulates rate and localization of homologous recombination in human cell lines with the alternative lengthening of telomeres (ALT) pathway Cancer Research. 77: 3470-3470. DOI: 10.1158/1538-7445.Am2017-3470  0.414
2017 Brosnan-Cashman JA, Rizzo AJ, Goger E, Myers KM, Zarinshenas R, Davis C, Yuan M, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract 3466: ALT-positive pediatric high grade glioma cells display chemosensitivity to ATR pathway inhibition Cancer Research. 77: 3466-3466. DOI: 10.1158/1538-7445.Am2017-3466  0.463
2017 Brosnan-Cashman JA, Yuan M, Rizzo AJ, Myers KM, Barry WT, Davis C, Esopi DM, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract 3465: Context-dependent effects of ATRX loss on telomere biology in glioma cells Cancer Research. 77: 3465-3465. DOI: 10.1158/1538-7445.Am2017-3465  0.495
2017 Rizzo AJ, Brosnan-Cashman JA, Graham MK, Meeker AK, Heaphy CM. Abstract 3464: CRISPR-mediated inactivation of ATRX and DAXX in pancreatic neuroendocrine tumor cell lines Cancer Research. 77: 3464-3464. DOI: 10.1158/1538-7445.Am2017-3464  0.776
2016 Weber KA, Heaphy CM, Rohrmann S, Gonzalez B, Bienstock JL, Agurs-Collins T, Platz EA, Meeker AK. Influence of In Utero Maternal and Neonate Factors on Cord Blood Leukocyte Telomere Length: Clues to the Racial Disparity in Prostate Cancer? Prostate Cancer. 2016: 3691650. PMID 28070423 DOI: 10.1155/2016/3691650  0.375
2016 Graham MK, Principessa L, Antony L, Meeker AK, Isaacs JT. Low p16(INK4a) Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone. The Prostate. PMID 27859428 DOI: 10.1002/Pros.23276  0.75
2016 Chalick M, Jacobi O, Pichinuk E, Garbar C, Bensussan A, Meeker A, Ziv R, Zehavi T, Smorodinsky NI, Hilkens J, Hanisch FG, Rubinstein DB, Wreschner DH. MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA. Plos One. 11: e0165031. PMID 27768738 DOI: 10.1371/Journal.Pone.0165031  0.323
2016 Kim JY, Brosnan-Cashman JA, An S, Kim SJ, Song KB, Kim MS, Kim MJ, Hwang DW, Meeker AK, Yu E, Kim SC, Hruban RH, Heaphy CM, Hong SM. Alternative lengthening of telomeres in primary pancreatic neuroendocrine neoplasms is associated with aggressive clinical behavior and poor survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27663587 DOI: 10.1158/1078-0432.Ccr-16-1147  0.32
2016 Cocks M, Taheri D, Ball MW, Bezerra SM, Del Carmen Rodriguez M, Ricardo BF, Bivalacqua TJ, Sharma RB, Meeker A, Chaux A, Burnett AL, Netto GJ. Immune checkpoint status in penile squamous cell carcinoma: A North American Cohort. Human Pathology. PMID 27663086 DOI: 10.1016/J.Humpath.2016.09.003  0.318
2016 Mukherjee A, Kumar B, Hatano K, Russell LM, Trock BJ, Searson PC, Meeker AK, Pomper MG, Lupold SE. Development and application of a novel model system to study 'active' and 'passive' tumor targeting. Molecular Cancer Therapeutics. PMID 27486224 DOI: 10.1158/1535-7163.Mct-16-0051  0.619
2016 Baras AS, Drake C, Liu JJ, Gandhi N, Kates M, Hoque MO, Meeker A, Hahn N, Taube JM, Schoenberg MP, Netto G, Bivalacqua TJ. The ratio of CD8 to Treg tumor-infiltrating lymphocytes is associated with response to cisplatin-based neoadjuvant chemotherapy in patients with muscle invasive urothelial carcinoma of the bladder. Oncoimmunology. 5: e1134412. PMID 27467953 DOI: 10.1080/2162402X.2015.1134412  0.346
2016 Hackeng WM, Brosens LA, Poruk KE, Noë M, Hosoda W, Poling JS, Rizzo A, Campbell-Thompson M, Atkinson MA, Konukiewitz B, Klöppel G, Heaphy CM, Meeker AK, Wood LD. Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis. Human Pathology. PMID 27342911 DOI: 10.1016/J.Humpath.2016.06.006  0.331
2016 Shekhani MT, Barber JR, Bezerra SM, Heaphy CM, Roibon ND, Taheri D, Reis LO, Guner G, Joshu CE, Netto GJ, Meeker AK. Hi-res telomere FISH reveals intriguing anomalies in germ cell tumors. Human Pathology. PMID 27085557 DOI: 10.1016/J.Humpath.2016.03.015  0.422
2016 Suryo Rahmanto Y, Jung JG, Wu RC, Kobayashi Y, Heaphy CM, Meeker AK, Wang TL, Shih IM. Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells. The Journal of Biological Chemistry. PMID 26953344 DOI: 10.1074/Jbc.M115.707612  0.403
2016 Koschmann C, Calinescu AA, Nunez FJ, Mackay A, Fazal-Salom J, Thomas D, Mendez F, Kamran N, Dzaman M, Mulpuri L, Krasinkiewicz J, Doherty R, Lemons R, Brosnan-Cashman JA, Li Y, ... ... Meeker A, et al. ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma. Science Translational Medicine. 8: 328ra28. PMID 26936505 DOI: 10.1126/Scitranslmed.Aac8228  0.328
2016 Thompson E, Taube JM, Elwood H, Sharma R, Meeker A, Warzecha HN, Argani P, Cimino-Mathews A, Emens LA. The immune microenvironment of breast ductal carcinoma in situ. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 29: 249-58. PMID 26769139 DOI: 10.1038/Modpathol.2015.158  0.318
2016 Haffner MC, Chaux A, Meeker AK, Esopi DM, Gerber J, Pellakuru LG, Toubaji A, Argani P, Iacobuzio-Donahue C, Nelson WG, Netto GJ, Marzo AMD, Yegnasubramanian S. Global 5-hydroxymethylcytosine content is significantly reduced in human cancers F1000research. 5. DOI: 10.7490/F1000Research.1113177.1  0.592
2016 Boudadi K, Suzman DL, Luber B, Wang H, Silberstein JL, Taylor MN, Sullivan R, Dowling D, Harb R, Dittamore RV, Meeker A, Luo J, Drake CG, Antonarakis ES. STARVE-PC: Biomarker-driven phase 2 study of ipilimumab plus nivolumab for AR-V7-expressing metastatic castration-resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 34: TPS5089-TPS5089. DOI: 10.1200/Jco.2016.34.15_Suppl.Tps5089  0.437
2016 Valle JABD, Zheng Q, Rubenstein M, Meeker AK, Heaphy CM, Hubbard G, Bieberich CJ, Yegnasubramanian S, Esopi D, Wheelan SJ, Marzo AMD. Abstract LB-160: Human telomerase RNA component (hTR/TERC) is consistently overexpressed in prostate cancer, required for cell proliferation and is positively regulated by MYC Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-160  0.707
2016 Graham MK, Brosnan-Cashman J, Rizzo A, Haffner M, Meeker A, Heaphy C. Abstract 4767: Generating and characterizing novel prostate cancer cell lines that employ the alternative lengthening of telomeres (ALT) telomere maintenance mechanism Cancer Research. 76: 4767-4767. DOI: 10.1158/1538-7445.Am2016-4767  0.813
2015 Wong HY, Wang GM, Croessmann S, Zabransky DJ, Chu D, Garay JP, Cidado J, Cochran RL, Beaver JA, Aggarwal A, Liu ML, Argani P, Meeker A, Hurley PJ, Lauring J, et al. TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer. Oncotarget. PMID 26702755 DOI: 10.18632/Oncotarget.6743  0.35
2015 Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin AR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, ... ... Meeker AK, et al. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars in Cancer Biology. 35: S276-304. PMID 26590477 DOI: 10.1016/J.Semcancer.2015.09.007  0.352
2015 Bodelon C, Heaphy CM, Meeker AK, Geller B, Vacek PM, Weaver DL, Chicoine RE, Shepherd JA, Mahmoudzadeh AP, Patel DA, Brinton LA, Sherman ME, Gierach GL. Leukocyte telomere length and its association with mammographic density and proliferative diagnosis among women undergoing diagnostic image-guided breast biopsy. Bmc Cancer. 15: 823. PMID 26519084 DOI: 10.1186/S12885-015-1860-2  0.307
2015 Yang HP, Meeker A, Guido R, Gunter MJ, Huang GS, Luhn P, d'Ambrosio L, Wentzensen N, Sherman ME. PTEN expression in benign human endometrial tissue and cancer in relation to endometrial cancer risk factors. Cancer Causes & Control : Ccc. PMID 26376893 DOI: 10.1007/S10552-015-0666-5  0.396
2015 Martin AM, Nirschl TR, Nirschl CJ, Francica BJ, Kochel CM, van Bokhoven A, Meeker AK, Lucia MS, Anders RA, DeMarzo AM, Drake CG. Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance. Prostate Cancer and Prostatic Diseases. PMID 26260996 DOI: 10.1038/Pcan.2015.39  0.443
2015 Cochran RL, Cidado J, Kim M, Zabransky DJ, Croessmann S, Chu D, Wong HY, Beaver JA, Cravero K, Erlanger B, Parsons H, Heaphy CM, Meeker AK, Lauring J, Park BH. Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes. Oncotarget. PMID 26246475 DOI: 10.18632/Oncotarget.4595  0.332
2015 Heaphy CM, Asch-Kendrick R, Argani P, Meeker AK, Cimino-Mathews A. Telomere length alterations unique to invasive lobular carcinoma. Human Pathology. 46: 1197-203. PMID 26092192 DOI: 10.1016/J.Humpath.2015.05.001  0.38
2015 Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Van Blarigan EL, Mucci LA, Giovannucci EL, Stampfer MJ, Yoon G, Lee TK, Hicks JL, De Marzo AM, Meeker AK, Platz EA. Prediagnostic Obesity and Physical Inactivity Are Associated with Shorter Telomere Length in Prostate Stromal Cells. Cancer Prevention Research (Philadelphia, Pa.). 8: 737-42. PMID 25990087 DOI: 10.1158/1940-6207.Capr-15-0097  0.502
2015 Heaphy CM, Gaonkar G, Peskoe SB, Joshu CE, De Marzo AM, Lucia MS, Goodman PJ, Lippman SM, Thompson IM, Platz EA, Meeker AK. Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial. The Prostate. 75: 1160-6. PMID 25893825 DOI: 10.1002/Pros.22997  0.552
2015 Ferguson LR, Chen H, Collins AR, Connell M, Damia G, Dasgupta S, Malhotra M, Meeker AK, Amedei A, Amin A, Ashraf SS, Aquilano K, Azmi AS, Bhakta D, Bilsland A, et al. Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. Seminars in Cancer Biology. PMID 25869442 DOI: 10.1016/J.Semcancer.2015.03.005  0.374
2015 Julin B, Shui I, Heaphy CM, Joshu CE, Meeker AK, Giovannucci E, De Vivo I, Platz EA. Circulating leukocyte telomere length and risk of overall and aggressive prostate cancer British Journal of Cancer. 112: 769-776. PMID 25562437 DOI: 10.1038/Bjc.2014.640  0.498
2015 Borodovsky A, Meeker AK, Kirkness EF, Zhao Q, Eberhart CG, Gallia GL, Riggins GJ. A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres. Journal of Neuro-Oncology. 121: 479-87. PMID 25471051 DOI: 10.1007/S11060-014-1672-2  0.303
2015 Weber KA, Heaphy CM, Giovannucci E, Platz EA, Meeker AK. Abstract 832: Midlife racial differences In leukocyte telomere length and in associations between modifiable factors and telomere length Cancer Research. 75: 832-832. DOI: 10.1158/1538-7445.Am2015-832  0.379
2015 Kim H, Wilsbach K, Marti A, Najafian A, Meeker AK, Eshleman JR, Bishop JA, Zeiger M, Umbricht CB. Abstract 4268: DNA copy number variation and driver mutation patterns of follicular thyroid tumors Cancer Research. 75: 4268-4268. DOI: 10.1158/1538-7445.Am2015-4268  0.359
2015 Shekhani MT, Barber J, Heaphy CM, Reis L, Guner G, Joshu C, Netto GJ, Meeker AK. Abstract 3783: High resolution telomere FISH analysis of testicular germ cell tumors reveals telomere anomalies specific to cancer subtypes and demonstrates telomere shortening as an early event in TGCT carcinogenesis Cancer Research. 75: 3783-3783. DOI: 10.1158/1538-7445.Am2015-3783  0.454
2015 Koschmann C, Calinescu A, Nunez F, Mckay A, Salom JF, Thomas D, Mulpuri L, Kamran N, Mendez F, Dzaman M, Krasinkiewicz J, Lemons R, Zhao L, Appelman H, Ferguson D, ... ... Meeker A, et al. PTPS-15ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS NON-HOMOLOGOUS END JOINING DNA REPAIR IN GLIOMA Neuro-Oncology. 17: v182.2-v182. DOI: 10.1093/Neuonc/Nov228.15  0.329
2015 Koschmann C, Calinescu A, Thomas D, Nunez FJ, Dzaman M, Krasinkiewicz J, Kamran N, Lemons R, Mendez F, Li Y, Ferguson D, Gorbunova V, Roh S, Zhao L, Meeker A, et al. HG-02 * ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS GENETIC STABILITY IN GLIOBLASTOMA Neuro-Oncology. 17: iii10-iii11. DOI: 10.1093/Neuonc/Nov061.39  0.332
2014 Zheng Q, Peskoe SB, Ribas J, Rafiqi F, Kudrolli T, Meeker AK, De Marzo AM, Platz EA, Lupold SE. Investigation of miR-21, miR-141, and miR-221 expression levels in prostate adenocarcinoma for associated risk of recurrence after radical prostatectomy. The Prostate. 74: 1655-62. PMID 25252191 DOI: 10.1002/Pros.22883  0.623
2014 Bhavsar NA, Bream JH, Meeker AK, Drake CG, Peskoe SB, Dabitao D, De Marzo AM, Isaacs WB, Platz EA. A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 2561-7. PMID 25150281 DOI: 10.1158/1055-9965.Epi-14-0010  0.524
2014 Mendonca J, Sharma A, Kim HS, Hammers H, Meeker A, De Marzo A, Carducci M, Kauffman M, Shacham S, Kachhap S. Selective inhibitors of nuclear export (SINE) as novel therapeutics for prostate cancer. Oncotarget. 5: 6102-12. PMID 25026284 DOI: 10.18632/Oncotarget.2174  0.519
2014 Zhang Y, Calado R, Rao M, Hong JA, Meeker AK, Dumitriu B, Atay S, McCormick PJ, Garfield SH, Wangsa D, Padilla-Nash HM, Burkett S, Zhang M, Kunst TF, Peterson NR, et al. Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas. Plos One. 9: e101010. PMID 24983628 DOI: 10.1371/Journal.Pone.0101010  0.446
2014 Capdevila J, Meeker A, García-Carbonero R, Pietras K, Astudillo A, Casanovas O, Scarpa A. Molecular biology of neuroendocrine tumors: from pathways to biomarkers and targets. Cancer Metastasis Reviews. 33: 345-51. PMID 24375391 DOI: 10.1007/S10555-013-9468-Y  0.31
2014 Hurwitz LM, Heaphy CM, Joshu CE, Isaacs WB, Konishi Y, De Marzo AM, Isaacs SD, Wiley KE, Platz EA, Meeker AK. Telomere length as a risk factor for hereditary prostate cancer. The Prostate. 74: 359-64. PMID 24285042 DOI: 10.1002/Pros.22755  0.643
2013 Haffner MC, Mosbruger T, Esopi DM, Fedor H, Heaphy CM, Walker DA, Adejola N, Gürel M, Hicks J, Meeker AK, Halushka MK, Simons JW, Isaacs WB, De Marzo AM, Nelson WG, et al. Tracking the clonal origin of lethal prostate cancer. The Journal of Clinical Investigation. 123: 4918-22. PMID 24135135 DOI: 10.1172/Jci70354  0.747
2013 Munari E, Fujita K, Faraj S, Chaux A, Gonzalez-Roibon N, Hicks J, Meeker A, Nonomura N, Netto GJ. Dysregulation of mammalian target of rapamycin pathway in upper tract urothelial carcinoma. Human Pathology. 44: 2668-76. PMID 24074531 DOI: 10.1016/J.Humpath.2013.07.008  0.332
2013 Heaphy CM, Schreck KC, Raabe E, Mao XG, An P, Chu Q, Poh W, Jiao Y, Rodriguez FJ, Odia Y, Meeker AK, Eberhart CG. A glioblastoma neurosphere line with alternative lengthening of telomeres. Acta Neuropathologica. 126: 607-8. PMID 24022427 DOI: 10.1007/S00401-013-1174-X  0.365
2013 Meeker A, Heaphy C. Gastroenteropancreatic endocrine tumors. Molecular and Cellular Endocrinology. 386: 101-20. PMID 23906538 DOI: 10.1016/J.Mce.2013.07.015  0.318
2013 Heaphy CM, Yoon GS, Peskoe SB, Joshu CE, Lee TK, Giovannucci E, Mucci LA, Kenfield SA, Stampfer MJ, Hicks JL, De Marzo AM, Platz EA, Meeker AK. Prostate cancer cell telomere length variability and stromal cell telomere length as prognostic markers for metastasis and death. Cancer Discovery. 3: 1130-41. PMID 23779129 DOI: 10.1158/2159-8290.Cd-13-0135  0.55
2013 Fahmy M, Mansure JJ, Brimo F, Yafi FA, Segal R, Althunayan A, Hicks J, Meeker A, Netto G, Kassouf W. Relevance of the mammalian target of rapamycin pathway in the prognosis of patients with high-risk non-muscle invasive bladder cancer. Human Pathology. 44: 1766-72. PMID 23623586 DOI: 10.1016/J.Humpath.2012.11.026  0.342
2013 Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA, Friedman AH, Friedman H, Gallia GL, Giovanella BC, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, ... ... Meeker AK, et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proceedings of the National Academy of Sciences of the United States of America. 110: 6021-6. PMID 23530248 DOI: 10.1093/Neuonc/Nou206.18  0.35
2013 Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ. Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathology (Zurich, Switzerland). 23: 237-43. PMID 22928601 DOI: 10.1111/J.1750-3639.2012.00630.X  0.317
2013 Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Mucci LA, Giovanucci E, Stampfer MJ, Yoon GS, Lee T, Hicks JL, Marzo AMD, Meeker AK, Platz EA. Abstract PR06: Prediagnostic obesity and inactivity are associated with shorter telomere length in prostate cancer-associated stromal cells Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Pr06  0.514
2013 Weber KA, Heaphy CM, Rohrmann S, Gonzalez B, Bienstock JL, Agurs-Collins T, Platz EA, Meeker AK. Abstract A63: Influence of in utero maternal and child factors on cord blood leukocyte telomere length and possible differences by race: Clues to the racial disparity in prostate cancer? Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-A63  0.427
2013 Heaphy CM, Haffner MC, Meeker AK. Abstract A06: A novel cell line model of the alternative lengthening of telomeres (ALT) telomere maintenance mechanism Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A06  0.481
2013 Bhavsar NA, Bream JJ, Meeker AK, Drake CG, Peskoe SB, Marzo AMD, Isaacs WB, Platz EA. Abstract 3618: Peripheral cytokine profiles and prostate cancer risk in CLUE II. Cancer Research. 73: 3618-3618. DOI: 10.1158/1538-7445.Am2013-3618  0.576
2013 Raval R, Ni X, Zhang Y, Zhou H, Meeker A, Lupold S, DeWeese T. Systemic Delivery of Synthesized Aptamer-siRNA Chimeras Results in Prostate-Targeted Radiosensitization International Journal of Radiation Oncology*Biology*Physics. 87: S139. DOI: 10.1016/J.Ijrobp.2013.06.358  0.681
2012 Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, ... ... Meeker AK, et al. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. Plos Genetics. 8: e1002772. PMID 22829774 DOI: 10.1371/Journal.Pgen.1002772  0.454
2012 de Wilde RF, Heaphy CM, Maitra A, Meeker AK, Edil BH, Wolfgang CL, Ellison TA, Schulick RD, Molenaar IQ, Valk GD, Vriens MR, Borel Rinkes IH, Offerhaus GJ, Hruban RH, Matsukuma KE. Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 25: 1033-9. PMID 22575867 DOI: 10.1038/Modpathol.2012.53  0.333
2012 Garay JP, Karakas B, Abukhdeir AM, Cosgrove DP, Gustin JP, Higgins MJ, Konishi H, Konishi Y, Lauring J, Mohseni M, Wang GM, Jelovac D, Weeraratna A, Sherman Baust CA, Morin PJ, ... ... Meeker A, et al. The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation. Breast Cancer Research : Bcr. 14: R27. PMID 22321971 DOI: 10.1186/Bcr3112  0.371
2012 Zhou X, Meeker AK, Makambi KH, Kosti O, Kallakury BV, Sidawy MK, Loffredo CA, Zheng YL. Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence. Carcinogenesis. 33: 113-8. PMID 22072619 DOI: 10.1093/Carcin/Bgr248  0.383
2012 Fahmy M, Mansure JJ, Brimo F, Yafi F, Segal R, Althunayan A, Netto G, Meeker A, Hicks J, Kassouf W. Abstract 1688: Relevance of mTOR pathway in prognosis of patients with urothelial carcinoma of the bladder Cancer Research. 72: 1688-1688. DOI: 10.1158/1538-7445.Am2012-1688  0.353
2012 Fahmy M, Mansure J, Brimo F, Yafi F, Althunayan A, Segal R, Netto G, Meeker A, Hicks J, Kassouf W. 1073 RELEVANCE OF MTOR PATHWAY IN PROGNOSIS OF PATIENTS WITH UROTHELIAL CARCINOMA OF THE BLADDER Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.1179  0.324
2011 Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, ... ... Meeker AK, et al. Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 17773-8. PMID 21987798 DOI: 10.1073/Pnas.1110969108  0.368
2011 Haffner MC, Chaux A, Meeker AK, Esopi DM, Gerber J, Pellakuru LG, Toubaji A, Argani P, Iacobuzio-Donahue C, Nelson WG, Netto GJ, De Marzo AM, Yegnasubramanian S. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget. 2: 627-37. PMID 21896958 DOI: 10.18632/Oncotarget.316  0.596
2011 Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih IeM, Iacobuzio-Donahue CA, Maitra A, Li QK, Eberhart CG, ... ... Meeker AK, et al. Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. The American Journal of Pathology. 179: 1608-15. PMID 21888887 DOI: 10.1016/J.Ajpath.2011.06.018  0.462
2011 Wang Y, Meeker AK, Kowalski J, Tsai HL, Somervell H, Heaphy C, Sangenario LE, Prasad N, Westra WH, Zeiger MA, Umbricht CB. Telomere length is related to alternative splice patterns of telomerase in thyroid tumors. The American Journal of Pathology. 179: 1415-24. PMID 21763260 DOI: 10.1016/J.Ajpath.2011.05.056  0.346
2011 Toubaji A, Albadine R, Meeker AK, Isaacs WB, Lotan T, Haffner MC, Chaux A, Epstein JI, Han M, Walsh PC, Partin AW, De Marzo AM, Platz EA, Netto GJ. Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 1511-20. PMID 21743434 DOI: 10.1038/Modpathol.2011.111  0.585
2011 Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, ... ... Meeker AK, et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science (New York, N.Y.). 333: 425. PMID 21719641 DOI: 10.1126/Science.1207313  0.34
2011 Chaux A, Albadine R, Toubaji A, Hicks J, Meeker A, Platz EA, De Marzo AM, Netto GJ. Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas. The American Journal of Surgical Pathology. 35: 1014-20. PMID 21677539 DOI: 10.1097/PAS.0b013e31821e8761  0.377
2011 Toivanen R, Berman DM, Wang H, Pedersen J, Frydenberg M, Meeker AK, Ellem SJ, Risbridger GP, Taylor RA. Brief report: a bioassay to identify primary human prostate cancer repopulating cells. Stem Cells (Dayton, Ohio). 29: 1310-4. PMID 21674698 DOI: 10.1002/Stem.668  0.507
2011 Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ, Eberhart CG. BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3590-9. PMID 21636552 DOI: 10.1158/1078-0432.Ccr-10-3349  0.357
2011 Kuhn E, Meeker AK, Visvanathan K, Gross AL, Wang TL, Kurman RJ, Shih IeM. Telomere length in different histologic types of ovarian carcinoma with emphasis on clear cell carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 1139-45. PMID 21499239 DOI: 10.1038/Modpathol.2011.67  0.326
2011 Haffner MC, De Marzo AM, Meeker AK, Nelson WG, Yegnasubramanian S. Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3858-64. PMID 21385925 DOI: 10.1158/1078-0432.Ccr-10-2044  0.645
2011 Heaphy CM, Meeker AK. The potential utility of telomere-related markers for cancer diagnosis. Journal of Cellular and Molecular Medicine. 15: 1227-38. PMID 21352473 DOI: 10.1111/J.1582-4934.2011.01284.X  0.483
2011 Lotan TL, Gupta NS, Wang W, Toubaji A, Haffner MC, Chaux A, Hicks JL, Meeker AK, Bieberich CJ, De Marzo AM, Epstein JI, Netto GJ. ERG gene rearrangements are common in prostatic small cell carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 820-8. PMID 21336263 DOI: 10.1038/Modpathol.2011.7  0.461
2011 Heaphy CM, Subhawong AP, Gross AL, Konishi Y, Kouprina N, Argani P, Visvanathan K, Meeker AK. Shorter telomeres in luminal B, HER-2 and triple-negative breast cancer subtypes. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 194-200. PMID 21057458 DOI: 10.1038/Modpathol.2010.198  0.374
2011 Hong SM, Heaphy CM, Shi C, Eo SH, Cho H, Meeker AK, Eshleman JR, Hruban RH, Goggins M. Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias Modern Pathology. 24: 256-266. PMID 20871595 DOI: 10.1038/Modpathol.2010.181  0.313
2011 Raabe EH, Lim KS, Mao X, Bar E, Meeker A, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG. Abstract 3303: BRAF activation induces cellular transformation and senescence and down-regulates SOX2 in human neural stem cells: a model of pilocytic astrocytoma Cancer Research. 71: 3303-3303. DOI: 10.1158/1538-7445.Am2011-3303  0.412
2011 Zeng Y, Shirashi T, Kim J, Mooney S, Meeker A, Luo J, Getzenberg R, Kulkarni P. 139 THE STRESS RESPONSE PROTEIN, PROSTATE ASSOCIATED GENE 4, IS ASSOCIATED WITH LESS AGGRESSIVE PROSTATE CANCER Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.206  0.537
2011 Chaux A, Albadine R, Toubaji A, Haffner M, Hicks J, Meeker A, Demarzo A, Platz E, Netto GJ. 618 IMMUNOHISTOCHEMISTRY FOR ERG EXPRESSION AS A SURROGATE FOR TMPRSS2-ERG FUSION DETECTION IN PROSTATIC ADENOCARCINOMA Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1471  0.374
2010 Hector A, Montgomery EA, Karikari C, Canto M, Dunbar KB, Wang JS, Feldmann G, Hong SM, Haffner MC, Meeker AK, Holland SJ, Yu J, Heckrodt TJ, Zhang J, Ding P, et al. The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma. Cancer Biology & Therapy. 10: 1009-18. PMID 20818175 DOI: 10.4161/Cbt.10.10.13248  0.353
2010 Haffner MC, Aryee MJ, Toubaji A, Esopi DM, Albadine R, Gurel B, Isaacs WB, Bova GS, Liu W, Xu J, Meeker AK, Netto G, De Marzo AM, Nelson WG, Yegnasubramanian S. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nature Genetics. 42: 668-75. PMID 20601956 DOI: 10.1038/Ng.613  0.726
2010 Kuhn E, Meeker A, Wang TL, Sehdev AS, Kurman RJ, Shih IeM. Shortened telomeres in serous tubal intraepithelial carcinoma: an early event in ovarian high-grade serous carcinogenesis. The American Journal of Surgical Pathology. 34: 829-36. PMID 20431479 DOI: 10.1097/Pas.0B013E3181Dcede7  0.398
2010 Nelson WG, Haffner MC, Aryee MJ, Esopi DM, Isaacs WB, Bova GS, Meeker AK, Netto G, Marzo AMD, Yegnasubramanian S. Abstract CN05-04: Early molecular changes in prostate carcinogenesis Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn05-04  0.737
2010 Kuhn E, Meeker A, Wang T, Sehdev AS, Kurman RJ, Shih I. Abstract LB-343: Shortened telomeres in serous tubal intraepithelial carcinoma: An early event in ovarian high-grade serous carcinogenesis Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-343  0.423
2010 Heaphy CM, Haffner MC, Meeker AK. Abstract 3212: Development of a chemiluminescence-based single telomere length analysis (STELA) method Cancer Research. 70: 3212-3212. DOI: 10.1158/1538-7445.Am10-3212  0.412
2010 Zhou X, Meeker A, Kallakury B, Sidawy M, Loffredo C, Zheng Y. Abstract 2684: Telomere length of carcinoma-associated fibroblasts as a biomarker for breast cancer local recurrence Cancer Research. 70: 2684-2684. DOI: 10.1158/1538-7445.Am10-2684  0.355
2010 Schultz L, Platz E, Toubaji A, Albadine R, Hicks J, Isaacs W, McEvoy C, Meeker A, De Marzo A, Netto G. 2128 LOSS OF PTEN EXPRESSION IS AN INDEPENDENT PREDICTOR OF RECURRENCE IN PROSTATE CARCINOMA Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.2216  0.57
2009 Albadine R, Latour M, Toubaji A, Haffner M, Isaacs WB, A Platz E, Meeker AK, Demarzo AM, Epstein JI, Netto GJ. TMPRSS2-ERG gene fusion status in minute (minimal) prostatic adenocarcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 1415-22. PMID 19734849 DOI: 10.1038/Modpathol.2009.121  0.568
2009 Subhawong AP, Heaphy CM, Argani P, Konishi Y, Kouprina N, Nassar H, Vang R, Meeker AK. The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 1423-31. PMID 19734843 DOI: 10.1038/Modpathol.2009.125  0.401
2009 Sfanos KS, Bruno TC, Meeker AK, De Marzo AM, Isaacs WB, Drake CG. Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+. The Prostate. 69: 1694-703. PMID 19670224 DOI: 10.1002/Pros.21020  0.558
2009 Koorstra JB, Hong SM, Shi C, Meeker AK, Ryu JK, Offerhaus GJ, Goggins MG, Hruban RH, Maitra A. Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 1439-45. PMID 19668150 DOI: 10.1038/Modpathol.2009.114  0.332
2009 Vander Griend DJ, Konishi Y, De Marzo AM, Isaacs JT, Meeker AK. Dual-label centromere and telomere FISH identifies human, rat, and mouse cell contribution to Multispecies recombinant urogenital sinus xenografts. The Prostate. 69: 1557-64. PMID 19562732 DOI: 10.1002/Pros.21001  0.399
2009 Fujita K, Pavlovich CP, Netto GJ, Konishi Y, Isaacs WB, Ali S, De Marzo A, Meeker AK. Specific detection of prostate cancer cells in urine by multiplex immunofluorescence cytology. Human Pathology. 40: 924-33. PMID 19368959 DOI: 10.1016/J.Humpath.2009.01.004  0.64
2009 Lotan TL, Toubaji A, Albadine R, Latour M, Herawi M, Meeker AK, DeMarzo AM, Platz EA, Epstein JI, Netto GJ. TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 359-65. PMID 19151660 DOI: 10.1038/Modpathol.2008.236  0.403
2009 Albadine R, Latour M, Platz E, Meeker A, Demazo A, Netto GJ. TMPRSS2-ERG GENE FUSIONS IN MINIMAL PROSTATIC CARCINOMA Journal of Urology. 181: 814-814. DOI: 10.1016/S0022-5347(09)62269-2  0.411
2008 Vander Griend DJ, Karthaus WL, Dalrymple S, Meeker A, DeMarzo AM, Isaacs JT. The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells. Cancer Research. 68: 9703-11. PMID 19047148 DOI: 10.1158/0008-5472.Can-08-3084  0.471
2008 Wang Y, Kowalski J, Tsai HL, Marik R, Prasad N, Somervell H, Lo PK, Sangenario LE, Dyrskjot L, Orntoft TF, Westra WH, Meeker AK, Eshleman JR, Umbricht CB, Zeiger MA. Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms. Thyroid : Official Journal of the American Thyroid Association. 18: 1055-63. PMID 18816183 DOI: 10.1089/Thy.2008.0101  0.304
2008 Sfanos KS, Bruno TC, Maris CH, Xu L, Thoburn CJ, DeMarzo AM, Meeker AK, Isaacs WB, Drake CG. Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3254-61. PMID 18519750 DOI: 10.1158/1078-0432.Ccr-07-5164  0.619
2008 Murray-Stewart T, Wang Y, Goodwin A, Hacker A, Meeker A, Casero RA. Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology. The Febs Journal. 275: 2795-806. PMID 18422650 DOI: 10.1111/J.1742-4658.2008.06419.X  0.313
2008 Cummings SD, Ryu B, Samuels MA, Yu X, Meeker AK, Healey MA, Alani RM. Id1 delays senescence of primary human melanocytes. Molecular Carcinogenesis. 47: 653-9. PMID 18240291 DOI: 10.1002/Mc.20422  0.346
2008 Joshua AM, Evans A, Van der Kwast T, Zielenska M, Meeker AK, Chinnaiyan A, Squire JA. Prostatic preneoplasia and beyond. Biochimica Et Biophysica Acta. 1785: 156-81. PMID 18166163 DOI: 10.1016/J.Bbcan.2007.12.001  0.495
2008 Bechan GI, Meeker AK, De Marzo AM, Racke F, Jaffe R, Sugar E, Arceci RJ. Telomere length shortening in Langerhans cell histiocytosis. British Journal of Haematology. 140: 420-8. PMID 18162125 DOI: 10.1182/Blood.V110.11.2411.2411  0.344
2007 Kawai T, Hiroi S, Nakanishi K, Meeker AK. Telomere length and telomerase expression in atypical adenomatous hyperplasia and small bronchioloalveolar carcinoma of the lung. American Journal of Clinical Pathology. 127: 254-62. PMID 17210516 DOI: 10.1309/91Py0Rbd9W8Y5Gnx  0.35
2007 De Marzo AM, Smearman E, Meeker A, Iwata T. 1131: Telomere Shortening in Prostate Atrophy Lesions Journal of Urology. 177: 373-373. DOI: 10.1016/S0022-5347(18)31345-4  0.406
2006 Palapattu GS, Meeker A, Harris T, Collector MI, Sharkis SJ, DeMarzo AM, Warlick C, Drake CG, Nelson WG. Epithelial architectural destruction is necessary for bone marrow derived cell contribution to regenerating prostate epithelium. The Journal of Urology. 176: 813-8. PMID 16813953 DOI: 10.1016/J.Juro.2006.03.077  0.383
2006 Hansel DE, Meeker AK, Hicks J, De Marzo AM, Lillemoe KD, Schulick R, Hruban RH, Maitra A, Argani P. Telomere length variation in biliary tract metaplasia, dysplasia, and carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 772-9. PMID 16557277 DOI: 10.1038/Modpathol.3800591  0.336
2006 Meeker AK. Telomeres and telomerase in prostatic intraepithelial neoplasia and prostate cancer biology. Urologic Oncology. 24: 122-30. PMID 16520276 DOI: 10.1016/J.Urolonc.2005.11.002  0.558
2006 Matsui W, Wang Q, Vala M, Barber JP, Meeker A, Tressler R, Harley C, Huff CA, Smith BD, Jones RJ. Cancer Stem Cell Targeting in Multiple Myeloma by GRN163L, a Novel and Potent Telomerase Inhibitor. Blood. 108: 2540-2540. DOI: 10.1182/Blood.V108.11.2540.2540  0.389
2004 Meeker AK, Argani P. Telomere shortening occurs early during breast tumorigenesis: a cause of chromosome destabilization underlying malignant transformation? Journal of Mammary Gland Biology and Neoplasia. 9: 285-96. PMID 15557801 DOI: 10.1023/B:Jomg.0000048775.04140.92  0.336
2004 Meeker AK, Hicks JL, Iacobuzio-Donahue CA, Montgomery EA, Westra WH, Chan TY, Ronnett BM, De Marzo AM. Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3317-26. PMID 15161685 DOI: 10.1158/1078-0432.Ccr-0984-03  0.466
2004 Montgomery E, Argani P, Hicks JL, DeMarzo AM, Meeker AK. Telomere lengths of translocation-associated and nontranslocation-associated sarcomas differ dramatically. The American Journal of Pathology. 164: 1523-9. PMID 15111298 DOI: 10.1016/S0002-9440(10)63710-8  0.354
2004 Meeker AK, Hicks JL, Gabrielson E, Strauss WM, De Marzo AM, Argani P. Telomere shortening occurs in subsets of normal breast epithelium as well as in situ and invasive carcinoma. The American Journal of Pathology. 164: 925-35. PMID 14982846 DOI: 10.1016/S0002-9440(10)63180-X  0.336
2004 De Marzo AM, DeWeese TL, Platz EA, Meeker AK, Nakayama M, Epstein JI, Isaacs WB, Nelson WG. Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment. Journal of Cellular Biochemistry. 91: 459-77. PMID 14755677 DOI: 10.1002/Jcb.10747  0.703
2004 Meeker AK, De Marzo AM. Recent advances in telomere biology: implications for human cancer. Current Opinion in Oncology. 16: 32-8. PMID 14685090 DOI: 10.1097/00001622-200401000-00007  0.472
2004 Marzo AMD, Nakayama M, Hicks JL, Meeker AK, Nelson WG. IL-11 Chronic inflammation, atrophy, and telomere length abnormalities in the pathogenesis of prostate cancer The Japanese Journal of Urology. 95: 276. DOI: 10.5980/Jpnjurol.95.276  0.439
2003 De Marzo AM, Meeker AK, Zha S, Luo J, Nakayama M, Platz EA, Isaacs WB, Nelson WG. Human prostate cancer precursors and pathobiology. Urology. 62: 55-62. PMID 14607218 DOI: 10.1016/J.Urology.2003.09.053  0.651
2002 Meeker AK, Hicks JL, Platz EA, March GE, Bennett CJ, Delannoy MJ, De Marzo AM. Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis. Cancer Research. 62: 6405-9. PMID 12438224  0.403
2002 van Heek NT, Meeker AK, Kern SE, Yeo CJ, Lillemoe KD, Cameron JL, Offerhaus GJ, Hicks JL, Wilentz RE, Goggins MG, De Marzo AM, Hruban RH, Maitra A. Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia. The American Journal of Pathology. 161: 1541-7. PMID 12414502 DOI: 10.1016/S0002-9440(10)64432-X  0.348
2002 Meeker AK, Gage WR, Hicks JL, Simon I, Coffman JR, Platz EA, March GE, De Marzo AM. Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining. The American Journal of Pathology. 160: 1259-68. PMID 11943711 DOI: 10.1016/S0002-9440(10)62553-9  0.375
1998 De Marzo AM, Nelson WG, Meeker AK, Coffey DS. Stem cell features of benign and malignant prostate epithelial cells. The Journal of Urology. 160: 2381-92. PMID 9817389 DOI: 10.1016/S0022-5347(01)62196-7  0.663
1998 De Marzo AM, Meeker AK, Epstein JI, Coffey DS. Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells. The American Journal of Pathology. 153: 911-9. PMID 9736039 DOI: 10.1016/S0002-9440(10)65632-5  0.664
1997 Meeker AK, Coffey DS. Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review. Biochemistry. Biokhimii︠a︡. 62: 1323-31. PMID 9467857  0.526
1996 Meeker AK, Sommerfeld HJ, Coffey DS. Telomerase is activated in the prostate and seminal vesicles of the castrated rat. Endocrinology. 137: 5743-6. PMID 8940411 DOI: 10.1210/Endo.137.12.8940411  0.641
1996 Sommerfeld HJ, Meeker AK, Piatyszek MA, Bova GS, Shay JW, Coffey DS. Telomerase activity: a prevalent marker of malignant human prostate tissue. Cancer Research. 56: 218-22. PMID 8548767  0.645
1995 Sommerfeld HJ, Meeker AK, Posadas EM, Coffey DS. Frontiers in prostate cancer: Telomeres and chaos Cancer. 75: 2027-2035. DOI: 10.1002/1097-0142(19950401)75:7+<2027::Aid-Cncr2820751645>3.0.Co;2-6  0.681
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