Kyle M. Schachtschneider, Ph.D. - Publications

Affiliations: 
2013 Animal Sciences University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Immunology, Genetics, Microbiology Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Segatto NV, Simões LD, Bender CB, Sousa FS, Oliveira TL, Paschoal JDF, Pacheco BS, Lopes I, Seixas FK, Qazi A, Thomas FM, Chaki S, Robertson N, Newsom J, Patel S, ... ... Schachtschneider KM, et al. Oncopig bladder cancer cells recapitulate human bladder cancer treatment responses . Frontiers in Oncology. 14: 1323422. PMID 38469237 DOI: 10.3389/fonc.2024.1323422  0.564
2023 Benjamin NR, Crooijmans RPMA, Jordan LR, Bolt CR, Schook LB, Schachtschneider KM, Groenen MAM, Roca AL. Swine global genomic resources: insights into wild and domesticated populations. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 37805667 DOI: 10.1007/s00335-023-10012-5  0.443
2023 Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, ... ... Schachtschneider KM, et al. DNA methylation networks underlying mammalian traits. Science (New York, N.Y.). 381: eabq5693. PMID 37561875 DOI: 10.1126/science.abq5693  0.462
2022 Elkhadragy L, Dasteh Goli K, Totura WM, Carlino MJ, Regan MR, Guzman G, Schook LB, Gaba RC, Schachtschneider KM. Effect of CRISPR Knockout of or on Proliferation and Migration of Porcine Hepatocellular Carcinoma. Frontiers in Oncology. 12: 904031. PMID 35669430 DOI: 10.3389/fonc.2022.904031  0.564
2022 Pirasteh A, Periyasamy S, Meudt JJ, Liu Y, Lee LM, Schachtschneider KM, Schook LB, Gaba RC, Mao L, Said A, McMillan AB, Laeseke PF, Shanmuganayagam D. Staging Liver Fibrosis by Fibroblast Activation Protein Inhibitor Positron Emission Tomography in a Human-sized Swine Model. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 35450958 DOI: 10.2967/jnumed.121.263736  0.442
2021 Schachtschneider KM, Schook LB, Meudt JJ, Shanmuganayagam D, Zoller JA, Haghani A, Li CZ, Zhang J, Yang A, Raj K, Horvath S. Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity. Geroscience. PMID 34523051 DOI: 10.1007/s11357-021-00439-6  0.478
2021 Boettcher AN, Schachtschneider KM, Schook LB, Tuggle CK. Swine models for translational oncological research: an evolving landscape and regulatory considerations. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 34476572 DOI: 10.1007/s00335-021-09907-y  0.532
2021 Segatto NV, Bender CB, Seixas FK, Schachtschneider K, Schook L, Robertson N, Qazi A, Carlino M, Jordan L, Bolt C, Collares T. Perspective: Humanized Pig Models of Bladder Cancer. Frontiers in Molecular Biosciences. 8: 681044. PMID 34079821 DOI: 10.3389/fmolb.2021.681044  0.556
2021 Patel SS, Sandur A, El-Kebir M, Gaba RC, Schook LB, Schachtschneider KM. Transcriptional Profiling of Porcine HCC Xenografts Provides Insights Into Tumor Cell Microenvironment Signaling. Frontiers in Genetics. 12: 657330. PMID 33995488 DOI: 10.3389/fgene.2021.657330  0.593
2021 Nurili F, Monette S, Michel AO, Bendet A, Basturk O, Askan G, Cheleuitte-Nieves C, Yarmohammadi H, Maxwell AWP, Ziv E, Schachtschneider KM, Gaba RC, Schook LB, Solomon SB, Boas FE. Transarterial Embolization of Liver Cancer in a Transgenic Pig Model. Journal of Vascular and Interventional Radiology : Jvir. PMID 33500185 DOI: 10.1016/j.jvir.2020.09.011  0.524
2021 Yasmin A, Regan DP, Schook LB, Gaba RC, Schachtschneider KM. Transcriptional regulation of alcohol induced liver fibrosis in a translational porcine hepatocellular carcinoma model. Biochimie. PMID 33444661 DOI: 10.1016/j.biochi.2020.12.022  0.561
2020 Elkhadragy L, Regan MR, M Totura W, Goli KD, Patel S, Garcia K, Stewart M, Schook LB, Gaba RC, Schachtschneider KM. Generation of genetically tailored porcine liver cancer cells by CRISPR/Cas9 editing. Biotechniques. PMID 33222517 DOI: 10.2144/btn-2020-0119  0.597
2020 Kim BS, Kim MK, Cho Y, Hamed EE, Gillette MU, Cha H, Miljkovic N, Aakalu VK, Kang K, Son KN, Schachtschneider KM, Schook LB, Hu C, Popescu G, Park Y, et al. Electrothermal soft manipulator enabling safe transport and handling of thin cell/tissue sheets and bioelectronic devices. Science Advances. 6. PMID 33067233 DOI: 10.1126/sciadv.abc5630  0.424
2020 Gaba RC, Elkhadragy L, Boas FE, Chaki S, Chen HH, El-Kebir M, Garcia KD, Giurini EF, Guzman G, LoBianco FV, Neto MF, Newson JL, Qazi A, Regan M, Rund LA, ... ... Schachtschneider KM, et al. Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation. Oncotarget. 11: 2686-2701. PMID 32733642 DOI: 10.18632/Oncotarget.27647  0.641
2020 Robertson N, Schook LB, Schachtschneider KM. Porcine cancer models: potential tools to enhance cancer drug trials. Expert Opinion On Drug Discovery. 1-10. PMID 32378979 DOI: 10.1080/17460441.2020.1757644  0.559
2020 Leitemberger A, Sonego MS, Garcia FD, Dos Santos ACF, Piccoli BC, da Silva FD, Oliveira CS, Seixas FK, Dornelles L, Rocha JBT, Nogara PA, Schachtschneider KM, Collares T, Rodrigues OED. Synthesis and biological evaluation of new antioxidant and antiproliferative chalcogenobiotin derivatives for bladder carcinoma treatment. Bioorganic & Medicinal Chemistry. 115423. PMID 32205047 DOI: 10.1016/J.Bmc.2020.115423  0.357
2020 Schachtschneider KM. The Promise of Improving Hepatocellular Carcinoma Treatment Responses through Translational Device Testing. Journal of Vascular and Interventional Radiology : Jvir. 31: 492-493. PMID 32085855 DOI: 10.1016/J.Jvir.2019.11.031  0.327
2020 Schachtschneider KM, Welge ME, Auvil LS, Chaki S, Rund LA, Madsen O, Elmore MRP, Johnson RW, Groenen MAM, Schook LB. Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults. Genes. 11. PMID 32033187 DOI: 10.3390/Genes11020162  0.535
2020 Elkhadragy L, Totura WM, Goli KD, Schook LB, Gaba RC, Schachtschneider KM. Abstract 6137: Development of ARID1A-deficient hepatocellular carcinoma in transgenic pigs Cancer Research. 80: 6137-6137. DOI: 10.1158/1538-7445.Am2020-6137  0.463
2020 Wang Y, Schachtschneider K, Huang Y, Gaba R, Nguyen P, Yen P, Sverdlov M, Guzman G, Lokken R. Abstract No. 707 Infiltration of T-cell subpopulations in hepatocellular carcinoma is associated with tumor size, Barcelona Clinic Liver Cancer stage, and transplant-free survival Journal of Vascular and Interventional Radiology. 31: S305. DOI: 10.1016/J.Jvir.2019.12.766  0.379
2020 Nurili F, Bendet A, Monette S, Michel A, Basturk O, Askan G, Cheleuitte-Nieves C, Yarmohammadi H, Schachtschneider K, Gaba R, Schook L, Solomon S, Boas F. 4:12 PM Abstract No. 198 Transarterial embolization of liver cancer in a transgenic pig model Journal of Vascular and Interventional Radiology. 31: S90-S91. DOI: 10.1016/J.Jvir.2019.12.237  0.567
2019 Sonego MS, Segatto NV, Damé L, Fronza M, Gomes CB, Oliveira TL, Seixas FK, Savegnago L, Schachtschneider KM, Alves D, Collares T. 7-Chloroquinoline-1,2,3-triazoyl carboxamides induce cell cycle arrest and apoptosis in human bladder carcinoma cells. Investigational New Drugs. PMID 31696365 DOI: 10.1007/S10637-019-00861-W  0.324
2019 Schachtschneider KM, Jungersen G, Schook LB, Shanmuganayagam D. Editorial: "Humanized" Large Animal Cancer Models: Accelerating Time and Effectiveness of Clinical Trials. Frontiers in Oncology. 9: 793. PMID 31508360 DOI: 10.3389/Fonc.2019.00793  0.563
2019 Benitez MLR, Bender CB, Oliveira TL, Schachtschneider KM, Collares T, Seixas FK. Mycobacterium bovis BCG in metastatic melanoma therapy. Applied Microbiology and Biotechnology. PMID 31402426 DOI: 10.1007/S00253-019-10057-0  0.301
2019 Couto GK, Segatto NV, Oliveira TL, Seixas FK, Schachtschneider KM, Collares T. The Melding of Drug Screening Platforms for Melanoma. Frontiers in Oncology. 9: 512. PMID 31293965 DOI: 10.3389/Fonc.2019.00512  0.312
2019 Singhal M, Khatibeghdami M, Principe DR, Mancinelli GE, Schachtschneider KM, Schook LB, Grippo PJ, Grimaldo SR. TM4SF18 is aberrantly expressed in pancreatic cancer and regulates cell growth. Plos One. 14: e0211711. PMID 30897168 DOI: 10.1371/Journal.Pone.0211711  0.57
2019 Xu C, Wu S, Schook LB, Schachtschneider KM. Translating Human Cancer Sequences Into Personalized Porcine Cancer Models. Frontiers in Oncology. 9: 105. PMID 30873383 DOI: 10.3389/Fonc.2019.00105  0.596
2019 Patel SS, Chaki S, Thomas FM, Qazi A, Schachtschneider KM, Stewart M, Pollack E, Gaba RC, Schook LB. Abstract 3711: Development, maintenance, and characterization of porcine hepatocellular carcinoma cell lines Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3711  0.578
2019 Qazi A, Thomas FM, Chaki S, Robertson N, Patel S, Schachtschneider KM, Schook LB. Abstract 3703: Development of oncopig urothelial carcinoma cell lines Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3703  0.557
2019 Schachtschneider KM, Lokken RP, Huang Y, Guzman G, Schook LB, Gaba RC. Abstract 4336: Epigenetic regulation of combined hepatocellular-cholangiocarcinoma subtypes Cancer Research. 79: 4336-4336. DOI: 10.1158/1538-7445.Am2019-4336  0.602
2019 Lobianco F, Giurini E, Neto M, Chen H, Chaki S, Newson J, Thomas F, Schook L, Schachtschneider K, Gaba R. 03:27 PM Abstract No. 221 Porcine and human hepatocellular carcinoma cell lines present similar drug-metabolizing enzyme expression levels and comparable sorafenib and doxorubicin cytotoxic responses Journal of Vascular and Interventional Radiology. 30: S99-S100. DOI: 10.1016/J.Jvir.2018.12.279  0.574
2018 Overgaard NH, Fan TM, Schachtschneider KM, Principe DR, Schook LB, Jungersen G. Of Mice, Dogs, Pigs, and Men: Choosing the Appropriate Model for Immuno-Oncology Research. Ilar Journal. PMID 30476148 DOI: 10.1093/Ilar/Ily014  0.585
2018 Overgaard NH, Principe DR, Schachtschneider KM, Jakobsen JT, Rund LA, Grippo PJ, Schook LB, Jungersen G. Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β T Cells and Differentiated γδ T Cells Alongside a Regulatory Response Mediated by FOXP3 T Cells and Immunoregulatory Molecules. Frontiers in Immunology. 9: 1301. PMID 29930558 DOI: 10.3389/Fimmu.2018.01301  0.546
2018 Gaba RC, Mendoza-Elias N, Regan DP, Garcia KD, Lokken RP, Schwind RM, Eichner M, Thomas FM, Rund LA, Schook LB, Schachtschneider KM. Characterization of an Inducible Alcoholic Liver Fibrosis Model for Hepatocellular Carcinoma Investigation in a Transgenic Porcine Tumorigenic Platform. Journal of Vascular and Interventional Radiology : Jvir. PMID 29887183 DOI: 10.1016/J.Jvir.2018.03.007  0.587
2018 Neto MF, Giurini EF, Chen HH, Newson JL, Schook LB, Schachtschneider KM, Gaba RC. Abstract 4094: Oncopig and human hepatocellular carcinoma cell lines exhibit similar response to liver cancer chemotherapy agents Tumor Biology. DOI: 10.1158/1538-7445.Am2018-4094  0.611
2018 Chen HH, Chaki S, Newson JL, Obeid M, Khabbaz RC, Yasmin A, Rund LA, Neto MF, Schook LB, Schachtschneider KM, Gaba RC. Abstract 4085: Development of porcine hepatocellular carcinoma cell lines: Comprehensive in vitro and in vivo characterization Tumor Biology. DOI: 10.1158/1538-7445.Am2018-4085  0.588
2018 Rund LA, Schachtschneider KM, Gaba RC, Principe DR, Grippo P, Schwind RM, Ozer H, Schook LB. Abstract 3105: Oncopig carcinoma cell lines: A foundation for co-clinical trials Cancer Research. 78: 3105-3105. DOI: 10.1158/1538-7445.Am2018-3105  0.613
2018 Thomas FM, Sutton BP, Wszalek TM, Dailey MJ, Schachtschneider KM, Schook LB, Gaba RC. Abstract 3047: Development and initial application of a porcine-specific MRI and MRE protocol for liver imaging in a large animal cancer model Tumor Biology. DOI: 10.1158/1538-7445.Am2018-3047  0.549
2018 Schachtschneider KM, Mendoza-Elias N, Regan DP, Garcia KD, Rund LA, Schwind RM, Schook LB, Gaba RC. Abstract 2088: Characterization of an inducible alcoholic liver fibrosis model for hepatocellular carcinoma investigation in a transgenic porcine platform Tumor Biology. DOI: 10.1158/1538-7445.Am2018-2088  0.566
2017 Segatto NV, Remião MH, Schachtschneider KM, Seixas FK, Schook LB, Collares T. The Oncopig Cancer Model as a Complementary Tool for Phenotypic Drug Discovery. Frontiers in Pharmacology. 8: 894. PMID 29259556 DOI: 10.3389/Fphar.2017.00894  0.567
2017 Schachtschneider KM, Schwind RM, Darfour-Oduro KA, De AK, Rund LA, Singh K, Principe DR, Guzman G, Ray CE, Ozer H, Gaba RC, Schook LB. A validated, transitional and translational porcine model of hepatocellular carcinoma. Oncotarget. 8: 63620-63634. PMID 28969016 DOI: 10.18632/Oncotarget.18872  0.628
2017 Schachtschneider KM, Schwind RM, Newson J, Kinachtchouk N, Rizko M, Mendoza-Elias N, Grippo P, Principe DR, Park A, Overgaard NH, Jungersen G, Garcia KD, Maker AV, Rund LA, Ozer H, et al. The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform. Frontiers in Oncology. 7: 190. PMID 28879168 DOI: 10.3389/Fonc.2017.00190  0.606
2017 Schachtschneider KM, Schwind RM, Darfour-Oduro KA, De AK, Rund LA, Singh K, Principe DR, Guzman G, Ray CE, Ozer H, Gaba RC, Schook LB. A validated, transitional and translational porcine model of hepatocellular carcinoma. Oncotarget. PMID 28733541 DOI: 10.18632/oncotarget.18872  0.589
2017 Schachtschneider KM, Liu Y, Mäkeläinen S, Madsen O, Rund LA, Groenen MAM, Schook LB. Oncopig Soft-Tissue Sarcomas Recapitulate Key Transcriptional Features of Human Sarcomas. Scientific Reports. 7: 2624. PMID 28572589 DOI: 10.1038/S41598-017-02912-9  0.59
2017 Newson J, Kinachtchouk N, Schachtschneider K, Schwind R, Schook L. Characteristics and Unmet Clinical Needs Related to Hepatocellular Carcinoma Digestive Disease Interventions. 1: 074-082. DOI: 10.1055/S-0037-1603812  0.595
2017 Schachtschneider K, Gaba R, Schwind R, Rund L, Ozer H, Ray C, Schook L. Validation of the oncopig platform as a translational porcine model for human hepatocellular carcinoma Journal of Vascular and Interventional Radiology. 28: S60. DOI: 10.1016/J.Jvir.2016.12.731  0.6
2016 Schachtschneider KM, Liu Y, Rund LA, Madsen O, Johnson RW, Groenen MA, Schook LB. Impact of neonatal iron deficiency on hippocampal DNA methylation and gene transcription in a porcine biomedical model of cognitive development. Bmc Genomics. 17: 856. PMID 27809765 DOI: 10.1186/S12864-016-3216-Y  0.517
2016 Derks MF, Schachtschneider KM, Madsen O, Schijlen E, Verhoeven KJ, van Oers K. Gene and transposable element methylation in great tit (Parus major) brain and blood. Bmc Genomics. 17: 332. PMID 27146629 DOI: 10.1186/S12864-016-2653-Y  0.315
2016 Ji P, Schachtschneider KM, Schook LB, Walker FR, Johnson RW. Peripheral Viral Infection Induced Microglial Sensome Genes and Enhanced Microglial Cell Activity in the Hippocampus of Neonatal Piglets. Brain, Behavior, and Immunity. PMID 26872419 DOI: 10.1016/J.Bbi.2016.02.010  0.511
2016 Schachtschneider KM, Rund LA, Madsen O, Johnson RW, Groenen MA, Schook LB. P2003 Altered hippocampal DNA methylation, gene transcription, and RNA editing in response to early life environmental insults in 2 independent studies of cognitive development Journal of Animal Science. 94: 39-39. DOI: 10.2527/Jas2016.94Supplement439X  0.51
2016 Schachtschneider KM, Derks MF, Madsen O, Laine VN, Schook LB, Groenen MA, Verhoeven KJ, van Oers K. P2002 The conserved functional role of non-CpG methylation in mammalian and avian brain Journal of Animal Science. 94: 38-38. DOI: 10.2527/Jas2016.94Supplement438A  0.479
2016 Darfour-Oduro KA, De AK, Rund LA, Gaba RC, Ray CE, Schwind RM, Schachtschneider KM, Singh KB, Schook LB. Abstract 4173: The oncopig cancer model as a validated model for human hepatocellular carcinoma Cancer Research. 76: 4173-4173. DOI: 10.1158/1538-7445.Am2016-4173  0.663
2016 De AK, Darfour-Oduro KA, Rund L, Schachtschneider KM, Singh K, Schook LB. Abstract 2050: Porcine drug metabolism and toxicityin vitromodel utilizing transformed hepatocyte cell lines (HepCre) Cancer Research. 76: 2050-2050. DOI: 10.1158/1538-7445.Am2016-2050  0.557
2015 Schachtschneider KM, Madsen O, Park C, Rund LA, Groenen MA, Schook LB. Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model. Bmc Genomics. 16: 743. PMID 26438392 DOI: 10.1186/S12864-015-1938-X  0.543
2015 Choi M, Lee J, Le MT, Nguyen DT, Park S, Soundrarajan N, Schachtschneider KM, Kim J, Park JK, Kim JH, Park C. Genome-wide analysis of DNA methylation in pigs using reduced representation bisulfite sequencing. Dna Research : An International Journal For Rapid Publication of Reports On Genes and Genomes. PMID 26358297 DOI: 10.1093/Dnares/Dsv017  0.336
2015 Schook LB, Collares TV, Hu W, Liang Y, Rodrigues FM, Rund LA, Schachtschneider KM, Seixas FK, Singh K, Wells KD, Walters EM, Prather RS, Counter CM. A Genetic Porcine Model of Cancer. Plos One. 10: e0128864. PMID 26132737 DOI: 10.1371/Journal.Pone.0128864  0.603
2015 Schook LB, Collares TV, Darfour-Oduro KA, De AK, Rund LA, Schachtschneider KM, Seixas FK. Unraveling the swine genome: implications for human health. Annual Review of Animal Biosciences. 3: 219-44. PMID 25689318 DOI: 10.1146/Annurev-Animal-022114-110815  0.567
2015 Ji P, Schachtschneider K, Schook L, Johnson R. Respiratory viral infection in neonatal piglets is associated with up regulation of microglial sensome transcripts in the hippocampus and increased microglial cell activity Brain, Behavior, and Immunity. 49: e21-e22. DOI: 10.1016/J.Bbi.2015.06.092  0.509
2013 Schachtschneider KM, Yeoman CJ, Isaacson RE, White BA, Schook LB, Pieters M. Modulation of systemic immune responses through commensal gastrointestinal microbiota. Plos One. 8: e53969. PMID 23326551 DOI: 10.1371/Journal.Pone.0053969  0.481
2012 Groenen MA, Archibald AL, Uenishi H, Tuggle CK, Takeuchi Y, Rothschild MF, Rogel-Gaillard C, Park C, Milan D, Megens HJ, Li S, Larkin DM, Kim H, Frantz LA, Caccamo M, ... ... Schachtschneider K, et al. Analyses of pig genomes provide insight into porcine demography and evolution. Nature. 491: 393-8. PMID 23151582 DOI: 10.1038/Nature11622  0.53
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