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Sai Prasad Pydi - Publications

Affiliations: 
National Institutes of Health, Bethesda, MD 
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Barella LF, Jain S, Pydi SP. G protein-coupled receptors: Role in metabolic disorders. Frontiers in Endocrinology. 13: 984253. PMID 35992121 DOI: 10.3389/fendo.2022.984253  0.335
2021 Meister J, Wang L, Pydi SP, Wess J. Chemogenetic approaches to identify metabolically important GPCR signaling pathways: therapeutic implications. Journal of Neurochemistry. PMID 33540469 DOI: 10.1111/jnc.15314  0.343
2020 Kimura T, Pydi SP, Pham J, Tanaka N. Metabolic Functions of G Protein-Coupled Receptors in Hepatocytes-Potential Applications for Diabetes and NAFLD. Biomolecules. 10. PMID 33076386 DOI: 10.3390/biom10101445  0.314
2020 Wang L, Zhu L, Meister J, Bone DBJ, Pydi SP, Rossi M, Wess J. Use of DREADD Technology to Identify Novel Targets for Antidiabetic Drugs. Annual Review of Pharmacology and Toxicology. PMID 32746768 DOI: 10.1146/Annurev-Pharmtox-030220-121042  0.463
2020 Pydi SP, Jain S, Barella LF, Zhu L, Sakamoto W, Meister J, Wang L, Lu H, Cui Y, Gavrilova O, Wess J. β-arrestin-1 suppresses myogenic reprogramming of brown fat to maintain euglycemia. Science Advances. 6: eaba1733. PMID 32548266 DOI: 10.1126/Sciadv.Aba1733  0.303
2020 Wang L, Pydi SP, Zhu L, Barella LF, Cui Y, Gavrilova O, Bence KK, Vernochet C, Wess J. Adipocyte G signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity. Nature Communications. 11: 2995. PMID 32532984 DOI: 10.1038/S41467-020-16756-X  0.357
2020 Dattaroy D, Barella LF, Pydi SP, Cui Y, Kaestner KH, Wess J. 2129-P: Glucagon Secretion from Pancreatic Islets Is Regulated by Beta-Arrestin-1 Diabetes. 69. DOI: 10.2337/Db20-2129-P  0.351
2020 Pydi SP, Jain S, Barella LF, Meister J, Wang L, Cui Y, Gavrilova O, Wess J. 1694-P: Beta-Arrestin 1 Suppresses Myogenic Reprogramming of Brown Fat to Maintain Euglycemia Diabetes. 69. DOI: 10.2337/Db20-1694-P  0.366
2019 Wang L, Pydi SP, Cui Y, Zhu L, Meister J, Gavrilova O, Berdeaux R, Fortin JP, Bence KK, Vernochet C, Wess J. Selective activation of G signaling in adipocytes causes striking metabolic improvements in mice. Molecular Metabolism. PMID 31272886 DOI: 10.1016/J.Molmet.2019.06.018  0.313
2019 Pydi SP, Jain S, Tung W, Cui Y, Zhu L, Sakamoto W, Jain S, Abel BS, Skarulis MC, Liu J, Huynh T, Pacak K, Caron MG, Gavrilova O, Finkel T, et al. Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis. Nature Communications. 10: 2936. PMID 31270323 DOI: 10.1038/S41467-019-11003-4  0.342
2019 WANG L, PYDI SP, ZHU L, JAIN S, CUI Y, GAVRILOVA O, WESS J. 1781-P: Adipocyte GI Signaling Regulates Whole-Body Glucose Homeostasis and Insulin Sensitivity Diabetes. 68: 1781-P. DOI: 10.2337/Db19-1781-P  0.324
2018 Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, et al. Hepatic Gi signaling regulates whole-body glucose homeostasis. The Journal of Clinical Investigation. PMID 29337301 DOI: 10.1172/Jci94505  0.331
2018 PYDI SP, WESS J. Adipocyte-Selective Deletion of ß-Arrestin-1 in Mice Causes Adiposity, Impaired Glucose Tolerance, and Reduced Insulin Sensitivity Diabetes. 67: 2034-P. DOI: 10.2337/Db18-2034-P  0.33
2016 Bhagirath AY, Pydi SP, Li Y, Lin C, Kong W, Chelikani P, Duan K. Characterization of the Direct Interaction between Hybrid Sensor Kinases PA1611 and RetS That Controls Biofilm Formation and the Type III Secretion System in Pseudomonas aeruginosa. Acs Infectious Diseases. PMID 27957853 DOI: 10.1021/Acsinfecdis.6B00153  0.64
2016 Pydi SP, Jafurulla M, Wai L, Bhullar RP, Chelikani P, Chattopadhyay A. Cholesterol modulates bitter taste receptor function. Biochimica Et Biophysica Acta. PMID 27288892 DOI: 10.1016/J.Bbamem.2016.06.005  0.721
2015 Pydi SP, Jaggupilli A, Nelson KM, Abrams SR, Bhullar RP, Loewen MC, Chelikani P. Abscisic Acid Acts as a Blocker of the Bitter Taste G Protein-Coupled Receptor T2R4. Biochemistry. 54: 2622-31. PMID 25844797 DOI: 10.1021/Acs.Biochem.5B00265  0.787
2014 Upadhyaya JD, Singh N, Sikarwar AS, Chakraborty R, Pydi SP, Bhullar RP, Dakshinamurti S, Chelikani P. Dextromethorphan mediated bitter taste receptor activation in the pulmonary circuit causes vasoconstriction. Plos One. 9: e110373. PMID 25340739 DOI: 10.1371/Journal.Pone.0110373  0.705
2014 Pydi SP, Sobotkiewicz T, Billakanti R, Bhullar RP, Loewen MC, Chelikani P. Amino acid derivatives as bitter taste receptor (T2R) blockers Journal of Biological Chemistry. 289: 25054-25066. PMID 25059668 DOI: 10.1074/Jbc.M114.576975  0.73
2014 Pydi SP, Bhullar RP, Chelikani P. Constitutive activity of bitter taste receptors (T2Rs). Advances in Pharmacology (San Diego, Calif.). 70: 303-26. PMID 24931200 DOI: 10.1016/B978-0-12-417197-8.00010-9  0.766
2014 Pydi SP, Singh N, Upadhyaya J, Bhullar RP, Chelikani P. The third intracellular loop plays a critical role in bitter taste receptor activation. Biochimica Et Biophysica Acta. 1838: 231-6. PMID 23994601 DOI: 10.1016/J.Bbamem.2013.08.009  0.806
2013 Pydi SP, Chakraborty R, Bhullar RP, Chelikani P. Role of rhodopsin N-terminus in structure and function of rhodopsin-bitter taste receptor chimeras. Biochemical and Biophysical Research Communications. 430: 179-82. PMID 23159609 DOI: 10.1016/J.Bbrc.2012.11.029  0.791
2013 Chakraborty R, Pydi SP, Gleim S, Bhullar RP, Hwa J, Dakshinamurti S, Chelikani P. New insights into structural determinants for prostanoid thromboxane A2 receptor- and prostacyclin receptor-G protein coupling. Molecular and Cellular Biology. 33: 184-93. PMID 23109431 DOI: 10.1128/Mcb.00725-12  0.782
2012 Pydi SP, Upadhyaya J, Singh N, Pal Bhullar R, Chelikani P. Recent advances in structure and function studies on human bitter taste receptors. Current Protein & Peptide Science. 13: 501-8. PMID 23061795 DOI: 10.2174/138920312803582942  0.801
2012 Pydi SP, Bhullar RP, Chelikani P. Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation. Journal of Neurochemistry. 122: 537-44. PMID 22639948 DOI: 10.1111/J.1471-4159.2012.07808.X  0.751
2012 Chakraborty R, Pydi SP, Gleim S, Dakshinamurti S, Hwa J, Chelikani P. Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4. Plos One. 7: e29996. PMID 22272267 DOI: 10.1371/Journal.Pone.0029996  0.78
2011 Singh N, Pydi SP, Upadhyaya J, Chelikani P. Structural basis of activation of bitter taste receptor T2R1 and comparison with Class A G-protein-coupled receptors (GPCRs). The Journal of Biological Chemistry. 286: 36032-36041. PMID 21852241 DOI: 10.1074/Jbc.M111.246983  0.81
2010 Upadhyaya J, Pydi SP, Singh N, Aluko RE, Chelikani P. Bitter taste receptor T2R1 is activated by dipeptides and tripeptides. Biochemical and Biophysical Research Communications. 398: 331-5. PMID 20599705 DOI: 10.1016/J.Bbrc.2010.06.097  0.769
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