Ezra R. Lowe, Ph.D. - Publications

Affiliations: 
2004 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Pharmacology

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Zhang F, Lowe ER, Rick DL, Qiu X, Leibold E, Cruzan G, Bartels MJ. In vitro metabolism, glutathione conjugation, and CYP isoform specificity of epoxidation of 4-vinylphenol. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 41: 6-23. PMID 20925585 DOI: 10.3109/00498254.2010.523735  0.302
2007 Osawa Y, Lau M, Lowe ER. Plant-Derived Small Molecule Inhibitors of Neuronal NO-Synthase: Potential Effects on Protein Degradation. Plant Signaling & Behavior. 2: 129-30. PMID 19704759 DOI: 10.4161/Psb.2.2.4071  0.632
2007 Lowe ER, Everett AC, Lau M, Dunbar AY, Michener D, Osawa Y. Naturally occurring neuronal NO-synthase inactivators found in Nicotiana tabacum (Solanaceae) and other plants. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 14: 344-52. PMID 17084601 DOI: 10.1016/J.Phymed.2006.09.004  0.76
2006 Dunbar AY, Jenkins GJ, Jianmongkol S, Nakatsuka M, Lowe ER, Lau M, Osawa Y. Tetrahydrobiopterin protects against guanabenz-mediated inhibition of neuronal nitric-oxide synthase in vitro and in vivo. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1448-56. PMID 16738031 DOI: 10.1124/Dmd.106.009951  0.8
2005 Kamada Y, Jenkins GJ, Lau M, Dunbar AY, Lowe ER, Osawa Y. Tetrahydrobiopterin depletion and ubiquitylation of neuronal nitric oxide synthase. Brain Research. Molecular Brain Research. 142: 19-27. PMID 16216381 DOI: 10.1016/J.Molbrainres.2005.09.003  0.804
2005 Lowe ER, Everett AC, Lee AJ, Lau M, Dunbar AY, Berka V, Tsai AL, Osawa Y. Time-dependent inhibition and tetrahydrobiopterin depletion of endothelial nitric-oxide synthase caused by cigarettes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 131-8. PMID 15470159 DOI: 10.1124/Dmd.104.001891  0.811
2004 Dunbar AY, Kamada Y, Jenkins GJ, Lowe ER, Billecke SS, Osawa Y. Ubiquitination and degradation of neuronal nitric-oxide synthase in vitro: dimer stabilization protects the enzyme from proteolysis. Molecular Pharmacology. 66: 964-9. PMID 15235101 DOI: 10.1124/Mol.104.000125  0.762
2003 Morishima Y, Kanelakis KC, Murphy PJ, Lowe ER, Jenkins GJ, Osawa Y, Sunahara RK, Pratt WB. The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex. The Journal of Biological Chemistry. 278: 48754-63. PMID 14507910 DOI: 10.1074/Jbc.M309814200  0.547
2003 Demady DR, Lowe ER, Everett AC, Billecke SS, Kamada Y, Dunbar AY, Osawa Y. Metabolism-based inactivation of neuronal nitric-oxide synthase by components of cigarette and cigarette smoke. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 932-7. PMID 12814971 DOI: 10.1124/Dmd.31.7.932  0.69
2003 Osawa Y, Lowe ER, Everett AC, Dunbar AY, Billecke SS. Proteolytic degradation of nitric oxide synthase: effect of inhibitors and role of hsp90-based chaperones. The Journal of Pharmacology and Experimental Therapeutics. 304: 493-7. PMID 12538799 DOI: 10.1124/Jpet.102.035055  0.765
2002 Vuletich JL, Lowe ER, Jianmongkol S, Kamada Y, Kent UM, Bender AT, Demady DR, Hollenberg PF, Osawa Y. Alteration of the heme prosthetic group of neuronal nitric-oxide synthase during inactivation by N(G)-amino-L-arginine in vitro and in vivo. Molecular Pharmacology. 62: 110-8. PMID 12065761 DOI: 10.1124/Mol.62.1.110  0.732
2002 Billecke SS, Bender AT, Kanelakis KC, Murphy PJ, Lowe ER, Kamada Y, Pratt WB, Osawa Y. hsp90 is required for heme binding and activation of apo-neuronal nitric-oxide synthase: geldanamycin-mediated oxidant generation is unrelated to any action of hsp90. The Journal of Biological Chemistry. 277: 20504-9. PMID 11923316 DOI: 10.1074/Jbc.M201940200  0.797
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