| Year |
Citation |
Score |
| 2021 |
Li Q, Jiang B, Guo J, Shao H, Del Priore IS, Chang Q, Kudo R, Li Z, Razavi P, Liu B, Boghossian AS, Rees MG, Ronan MM, Roth JA, Donovan KA, ... ... Koff A, et al. INK4 tumor suppressor proteins mediate resistance to CDK4/6 kinase inhibitors. Cancer Discovery. PMID 34544752 DOI: 10.1158/2159-8290.CD-20-1726 |
0.303 |
|
| 2019 |
Dickson MA, Koff A, D'Angelo SP, Gounder MM, Keohan ML, Kelly CM, Chi P, Antonescu CR, Landa J, Qin L, Crago AM, Singer S, Tap WD. Phase 2 study of the CDK4 inhibitor abemaciclib in dedifferentiated liposarcoma. Journal of Clinical Oncology. 37: 11004-11004. DOI: 10.1200/Jco.2019.37.15_Suppl.11004 |
0.325 |
|
| 2018 |
Klein ME, Dickson MA, Antonescu C, Qin LX, Dooley SJ, Barlas A, Manova K, Schwartz GK, Crago AM, Singer S, Koff A, Tap WD. PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence. Oncogene. PMID 29789718 DOI: 10.1038/S41388-018-0332-Y |
0.447 |
|
| 2018 |
Klein ME, Kovatcheva M, Davis LE, Tap WD, Koff A. CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once Thought. Cancer Cell. PMID 29731395 DOI: 10.1016/J.Ccell.2018.03.023 |
0.354 |
|
| 2018 |
Kovatcheva M, Klein ME, Tap WD, Koff A. Mechanistic understanding of the role of ATRX in senescence provides new insight for combinatorial therapies with CDK4 inhibitors. Molecular & Cellular Oncology. 5: e1384882. PMID 29404388 DOI: 10.1080/23723556.2017.1384882 |
0.309 |
|
| 2017 |
Kovatcheva M, Liao W, Klein ME, Robine N, Geiger H, Crago AM, Dickson MA, Tap WD, Singer S, Koff A. ATRX is a regulator of therapy induced senescence in human cells. Nature Communications. 8: 386. PMID 28855512 DOI: 10.1038/S41467-017-00540-5 |
0.47 |
|
| 2016 |
Dickson MA, Schwartz GK, Keohan ML, D'Angelo SP, Gounder MM, Chi P, Antonescu CR, Landa J, Qin LX, Crago AM, Singer S, Koff A, Tap WD. Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial. Jama Oncology. PMID 27124835 DOI: 10.1001/Jamaoncol.2016.0264 |
0.34 |
|
| 2015 |
Kovatcheva M, Liu DD, Dickson MA, Klein ME, O'Connor R, Wilder FO, Socci ND, Tap WD, Schwartz GK, Singer S, Crago AM, Koff A. MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. Oncotarget. 6: 8226-43. PMID 25803170 DOI: 10.18632/Oncotarget.3364 |
0.545 |
|
| 2014 |
Raheja R, Liu Y, Hukkelhoven E, Yeh N, Koff A. The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activity. The Biochemical Journal. 458: 537-45. PMID 24393003 DOI: 10.1042/Bj20131288 |
0.4 |
|
| 2014 |
Liu Y, Raheja R, Yeh N, Ciznadija D, Pedraza AM, Ozawa T, Hukkelhoven E, Erdjument-Bromage H, Tempst P, Gauthier NP, Brennan C, Holland EC, Koff A. TRIM3, a tumor suppressor linked to regulation of p21 Waf1/Cip1 Oncogene. 33: 308-315. PMID 23318451 DOI: 10.1038/Onc.2012.596 |
0.417 |
|
| 2013 |
Pérez-Sanz J, Arluzea J, Matorras R, González-Santiago N, Bilbao J, Yeh N, Barlas A, Romin Y, Manova-Todorova K, Koff A, De La Hoz C. Increased number of multi-oocyte follicles (MOFs) in juvenile p27Kip1 mutant mice: Potential role of granulosa cells Human Reproduction. 28: 1023-1030. PMID 23300200 DOI: 10.1093/Humrep/Des436 |
0.351 |
|
| 2012 |
Hukkelhoven E, Liu Y, Yeh N, Ciznadija D, Blain SW, Koff A. Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma. The Journal of Biological Chemistry. 287: 38523-30. PMID 23007395 DOI: 10.1074/Jbc.M112.366542 |
0.458 |
|
| 2012 |
Miller JP, Yeh N, Hofstetter CP, Keskin D, Goldstein AS, Koff A. p27kip1 protein levels reflect a nexus of oncogenic signaling during cell transformation. The Journal of Biological Chemistry. 287: 19775-85. PMID 22511779 DOI: 10.1074/Jbc.M112.361972 |
0.404 |
|
| 2011 |
Ciznadija D, Liu Y, Pyonteck SM, Holland EC, Koff A. Cyclin D1 and cdk4 mediate development of neurologically destructive oligodendroglioma. Cancer Research. 71: 6174-83. PMID 21844184 DOI: 10.1158/0008-5472.Can-11-1031 |
0.39 |
|
| 2011 |
Ciznadija D, Zhu XH, Koff A. Hdm2- and proteasome-dependent turnover limits p21 accumulation during S phase. Cell Cycle (Georgetown, Tex.). 10: 2714-23. PMID 21768776 DOI: 10.4161/Cc.10.16.16725 |
0.54 |
|
| 2010 |
Brill E, Gobble R, Angeles C, Lagos-Quintana M, Crago A, Laxa B, Decarolis P, Zhang L, Antonescu C, Socci ND, Taylor BS, Sander C, Koff A, Singer S. ZIC1 overexpression is oncogenic in liposarcoma. Cancer Research. 70: 6891-901. PMID 20713527 DOI: 10.1158/0008-5472.Can-10-0745 |
0.409 |
|
| 2010 |
See WL, Miller JP, Squatrito M, Holland E, Resh MD, Koff A. Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas. Oncogene. 29: 1720-31. PMID 20062078 DOI: 10.1038/Onc.2009.465 |
0.545 |
|
| 2009 |
Liu Y, Elf SE, Asai T, Miyata Y, Liu Y, Sashida G, Huang G, Di Giandomenico S, Koff A, Nimer SD. The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior. Cell Cycle (Georgetown, Tex.). 8: 3120-4. PMID 19755852 DOI: 10.4161/Cc.8.19.9627 |
0.464 |
|
| 2009 |
Liu L, Lee S, Zhang J, Peters SB, Hannah J, Zhang Y, Yin Y, Koff A, Ma L, Zhou P. CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis. Molecular Cell. 34: 451-60. PMID 19481525 DOI: 10.1016/J.Molcel.2009.04.020 |
0.316 |
|
| 2009 |
Liu Y, Elf SE, Miyata Y, Sashida G, Liu Y, Huang G, Di Giandomenico S, Lee JM, Deblasio A, Menendez S, Antipin J, Reva B, Koff A, Nimer SD. p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell. 4: 37-48. PMID 19128791 DOI: 10.1016/J.Stem.2008.11.006 |
0.456 |
|
| 2007 |
Miller JP, Yeh N, Vidal A, Koff A. Interweaving the cell cycle machinery with cell differentiation. Cell Cycle (Georgetown, Tex.). 6: 2932-8. PMID 18000404 DOI: 10.4161/Cc.6.23.5042 |
0.487 |
|
| 2007 |
Liu Y, Yeh N, Zhu XH, Leversha M, Cordon-Cardo C, Ghossein R, Singh B, Holland E, Koff A. Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1). The Embo Journal. 26: 4683-93. PMID 17948060 DOI: 10.1038/Sj.Emboj.7601886 |
0.479 |
|
| 2007 |
Smartt HJ, Guilmeau S, Nasser SV, Nicholas C, Bancroft L, Simpson SA, Yeh N, Yang W, Mariadason JM, Koff A, Augenlicht LH. p27kip1 Regulates cdk2 activity in the proliferating zone of the mouse intestinal epithelium: potential role in neoplasia. Gastroenterology. 133: 232-43. PMID 17631145 DOI: 10.1053/J.Gastro.2007.04.043 |
0.438 |
|
| 2007 |
Yeh N, Miller JP, Gaur T, Capellini TD, Nikolich-Zugich J, de la Hoz C, Selleri L, Bromage TG, van Wijnen AJ, Stein GS, Lian JB, Vidal A, Koff A. Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130. Molecular and Cellular Biology. 27: 5161-71. PMID 17502351 DOI: 10.1128/Mcb.02431-06 |
0.486 |
|
| 2007 |
Liu Y, Elf SE, Miyata Y, Sashida G, Deblasio AD, Liu Y, Koff A, Nimer SD. Regulation of Hematopoietic Stem Cell Quiescence - A Novel Role for p53. Blood. 110: 92-92. DOI: 10.1182/Blood.V110.11.92.92 |
0.442 |
|
| 2006 |
Hulit J, Lee RJ, Li Z, Wang C, Katiyar S, Yang J, Quong AA, Wu K, Albanese C, Russell R, Di Vizio D, Koff A, Thummala S, Zhang H, Harrell J, et al. p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling. Cancer Research. 66: 8529-41. PMID 16951165 DOI: 10.1158/0008-5472.Can-06-0149 |
0.409 |
|
| 2006 |
Refik-Rogers J, Manova K, Koff A. Misexpression of cyclin B3 leads to aberrant spermatogenesis. Cell Cycle (Georgetown, Tex.). 5: 1966-73. PMID 16929180 DOI: 10.4161/Cc.5.17.3137 |
0.726 |
|
| 2006 |
Guidi CJ, Mudhasani R, Hoover K, Koff A, Leav I, Imbalzano AN, Jones SN. Functional interaction of the retinoblastoma and Ini1/Snf5 tumor suppressors in cell growth and pituitary tumorigenesis. Cancer Research. 66: 8076-82. PMID 16912184 DOI: 10.1158/0008-5472.Can-06-1451 |
0.43 |
|
| 2006 |
Liu Y, Hedvat CV, Mao S, Zhu XH, Yao J, Nguyen H, Koff A, Nimer SD. The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2. Molecular and Cellular Biology. 26: 3114-23. PMID 16581786 DOI: 10.1128/Mcb.26.8.3114-3123.2006 |
0.531 |
|
| 2006 |
Koff A. How to decrease p27Kip1 levels during tumor development. Cancer Cell. 9: 75-6. PMID 16473274 DOI: 10.1016/J.Ccr.2006.01.020 |
0.358 |
|
| 2006 |
Liu Y, Miyata Y, Sashida G, Debalsio A, Liu Y, Koff A, Nimer SD. Genetic Uncoupling of the Regulation of Hematopoietic Stem Cell Quiescence and Self-Renewal. Blood. 108: 1347-1347. DOI: 10.1182/Blood.V108.11.1347.1347 |
0.421 |
|
| 2005 |
Sakakibara K, Kubota K, Worku B, Ryer EJ, Miller JP, Koff A, Kent KC, Liu B. PDGF-BB regulates p27 expression through ERK-dependent RNA turn-over in vascular smooth muscle cells. The Journal of Biological Chemistry. 280: 25470-7. PMID 15894805 DOI: 10.1074/Jbc.M502320200 |
0.504 |
|
| 2005 |
Vidal A, Zacharoulis S, Guo W, Shaffer D, Giancotti F, Bramley AH, de la Hoz C, Jensen KK, Kato D, MacDonald DD, Knowles J, Yeh N, Frohman LA, Rafii S, Lyden D, ... Koff A, et al. p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 102: 6890-5. PMID 15867156 DOI: 10.1073/Pnas.0405823102 |
0.405 |
|
| 2005 |
Shaffer DR, Viale A, Ishiwata R, Leversha M, Olgac S, Manova K, Satagopan J, Scher H, Koff A. Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate. Proceedings of the National Academy of Sciences of the United States of America. 102: 210-5. PMID 15615849 DOI: 10.1073/Pnas.0407362102 |
0.479 |
|
| 2004 |
Zhu XH, Nguyen H, Halicka HD, Traganos F, Koff A. Noncatalytic requirement for cyclin A-cdk2 in p27 turnover. Molecular and Cellular Biology. 24: 6058-66. PMID 15199159 DOI: 10.1128/Mcb.24.13.6058-6066.2004 |
0.56 |
|
| 2003 |
Carneiro C, Jiao MS, Hu M, Shaffer D, Park M, Pandolfi PP, Cordon-Cardo C, Koff A. p27 deficiency desensitizes Rb-/- cells to signals that trigger apoptosis during pituitary tumor development. Oncogene. 22: 361-9. PMID 12545157 DOI: 10.1038/Sj.Onc.1206163 |
0.443 |
|
| 2002 |
Nguyen TB, Manova K, Capodieci P, Lindon C, Bottega S, Wang XY, Refik-Rogers J, Pines J, Wolgemuth DJ, Koff A. Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin. The Journal of Biological Chemistry. 277: 41960-9. PMID 12185076 DOI: 10.1074/Jbc.M203951200 |
0.708 |
|
| 2002 |
Vidal A, Millard SS, Miller JP, Koff A. Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status. The Journal of Biological Chemistry. 277: 16433-40. PMID 11875067 DOI: 10.1074/Jbc.M112090200 |
0.553 |
|
| 2002 |
Mahoney JA, Odin JA, White SM, Shaffer D, Koff A, Casciola-Rosen L, Rosen A. The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis. The Biochemical Journal. 361: 587-95. PMID 11802788 DOI: 10.1042/Bj3610587 |
0.335 |
|
| 2001 |
Park MS, Koff A. Overview of the cell cycle Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. PMID 18228386 DOI: 10.1002/0471143030.Cb0801S00 |
0.536 |
|
| 2001 |
Gitig DM, Koff A. Cdk pathway: cyclin-dependent kinases and cyclin-dependent kinase inhibitors. Molecular Biotechnology. 19: 179-88. PMID 11725487 DOI: 10.1385/Mb:19:2:179 |
0.804 |
|
| 2001 |
Cipriano SC, Chen L, Burns KH, Koff A, Matzuk MM. Inhibin and p27 interact to regulate gonadal tumorigenesis Molecular Endocrinology. 15: 985-996. PMID 11376116 DOI: 10.1210/Mend.15.6.0650 |
0.427 |
|
| 2001 |
Zezula J, Casaccia-Bonnefil P, Ezhevsky SA, Osterhout DJ, Levine JM, Dowdy SF, Chao MV, Koff A. p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal. Embo Reports. 2: 27-34. PMID 11252720 DOI: 10.1093/Embo-Reports/Kve008 |
0.499 |
|
| 2001 |
Di Cristofano A, De Acetis M, Koff A, Cordon-Cardo C, P Pandolfi P. Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse Nature Genetics. 27: 222-224. PMID 11175795 DOI: 10.1038/84879 |
0.349 |
|
| 2000 |
Millard SS, Vidal A, Markus M, Koff A. A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA. Molecular and Cellular Biology. 20: 5947-59. PMID 10913178 DOI: 10.1128/Mcb.20.16.5947-5959.2000 |
0.437 |
|
| 2000 |
Vairo G, Soos TJ, Upton TM, Zalvide J, DeCaprio JA, Ewen ME, Koff A, Adams JM. Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation. Molecular and Cellular Biology. 20: 4745-53. PMID 10848600 DOI: 10.1128/Mcb.20.13.4745-4753.2000 |
0.8 |
|
| 2000 |
Gitig DM, Koff A. Cdk pathway: cyclin-dependent kinases and cyclin-dependent kinase inhibitors. Methods in Molecular Biology (Clifton, N.J.). 142: 109-23. PMID 10806617 DOI: 10.1385/1-59259-053-5:109 |
0.804 |
|
| 2000 |
Vidal A, Koff A. Cell-cycle inhibitors: Three families united by a common cause Gene. 247: 1-15. PMID 10773440 DOI: 10.1016/S0378-1119(00)00092-5 |
0.51 |
|
| 2000 |
Tsutsui T, Hesabi B, Moons DS, Pandolfi PP, Hansel KS, Koff A, Kiyokawa H. Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Molecular and Cellular Biology. 19: 7011-9. PMID 10490638 DOI: 10.1128/Mcb.19.10.7011 |
0.596 |
|
| 1999 |
Chou JL, Fan Z, DeBlasio T, Koff A, Rosen N, Mendelsohn J. Constitutive overexpression of cyclin D1 in human breast epithelial cells does not prevent G1 arrest induced by deprivation of epidermal growth factor Breast Cancer Research and Treatment. 55: 267-283. PMID 10517171 DOI: 10.1023/A:1006217413089 |
0.528 |
|
| 1999 |
Kolluri SK, Weiss C, Koff A, Göttlicher M. p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells. Genes & Development. 13: 1742-53. PMID 10398686 DOI: 10.1101/Gad.13.13.1742 |
0.512 |
|
| 1999 |
Park MS, Rosai J, Nguyen HT, Capodieci P, Cordon-Cardo C, Koff A. p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 6382-7. PMID 10339596 DOI: 10.1073/Pnas.96.11.6382 |
0.435 |
|
| 1999 |
Beumer TL, Kiyokawa H, Roepers-Gajadien HL, van den Bos LA, Lock TM, Gademan IS, Rutgers DH, Koff A, de Rooij DG. Regulatory role of p27kip1 in the mouse and human testis. Endocrinology. 140: 1834-40. PMID 10098522 DOI: 10.1210/Endo.140.4.6638 |
0.535 |
|
| 1999 |
Nguyen H, Gitig DM, Koff A. Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome. Molecular and Cellular Biology. 19: 1190-201. PMID 9891053 DOI: 10.1128/Mcb.19.2.1190 |
0.794 |
|
| 1998 |
Millard SS, Koff A. Cyclin-dependent kinase inhibitors in restriction point control, genomic stability, and tumorigenesis. Journal of Cellular Biochemistry. Supplement. 30: 37-42. PMID 9893253 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<37::Aid-Jcb6>3.0.Co;2-W |
0.362 |
|
| 1998 |
Tong W, Kiyokawa H, Soos TJ, Park MS, Soares VC, Manova K, Pollard JW, Koff A. The absence of p27Kip1, an inhibitor of G1 cyclin-dependent kinases, uncouples differentiation and growth arrest during the granulosa->luteal transition. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 787-94. PMID 9751122 |
0.8 |
|
| 1998 |
Tikoo R, Osterhout DJ, Casaccia-Bonnefil P, Seth P, Koff A, Chao MV. Ectopic expression of p27Kip1 in oligodendrocyte progenitor cells results in cell-cycle growth arrest. Journal of Neurobiology. 36: 431-40. PMID 9733077 DOI: 10.1002/(Sici)1097-4695(19980905)36:3<431::Aid-Neu10>3.0.Co;2-E |
0.567 |
|
| 1998 |
Soos TJ, Park M, Kiyokawa H, Koff A. Regulation of the cell cycle by CDK inhibitors. Results and Problems in Cell Differentiation. 22: 111-31. PMID 9670321 DOI: 10.1007/978-3-540-69686-5_5 |
0.81 |
|
| 1997 |
Osman I, Scher H, Zhang ZF, Soos TJ, Hamza R, Eissa S, Khaled H, Koff A, Cordon-Cardo C. Expression of cyclin D1, but not cyclins E and A, is related to progression in bilharzial bladder cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 3: 2247-51. PMID 9815621 |
0.767 |
|
| 1997 |
Casaccia-Bonnefil P, Tikoo R, Kiyokawa H, Friedrich V, Chao MV, Koff A. Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1. Genes & Development. 11: 2335-46. PMID 9308962 DOI: 10.1101/Gad.11.18.2335 |
0.435 |
|
| 1997 |
Millard SS, Yan JS, Nguyen H, Pagano M, Kiyokawa H, Koff A. Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. The Journal of Biological Chemistry. 272: 7093-8. PMID 9054402 DOI: 10.1074/Jbc.272.11.7093 |
0.561 |
|
| 1997 |
Tikoo R, Casaccia-Bonnefil P, Chao MV, Koff A. Changes in cyclin-dependent kinase 2 and p27kip1 accompany glial cell differentiation of central glia-4 cells. The Journal of Biological Chemistry. 272: 442-7. PMID 8995281 DOI: 10.1074/Jbc.272.1.442 |
0.539 |
|
| 1997 |
Luo Y, Marx SO, Kiyokawa H, Koff A, Massagué J, Marks AR. Rapamycin resistance tied to defective regulation of p27Kip1. Molecular and Cellular Biology. 16: 6744-51. PMID 8943329 DOI: 10.1128/Mcb.16.12.6744 |
0.465 |
|
| 1996 |
Missero C, Di Cunto F, Kiyokawa H, Koff A, Dotto GP. The absence of p21(Cip1/WAF1) alters keratinocyte growth and differentiation and promotes ras-tumor progression Genes and Development. 10: 3065-3075. PMID 8957006 |
0.344 |
|
| 1996 |
Soos TJ, Kiyokawa H, Yan JS, Rubin MS, Giordano A, DeBlasio A, Bottega S, Wong B, Mendelsohn J, Koff A. Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 7: 135-46. PMID 8822197 |
0.815 |
|
| 1996 |
Onel K, Koff A, Bennett RL, Unrau P, Holloman WK. The REC1 gene of Ustilago maydis, which encodes a 3'-->5' exonuclease, couples DNA repair and completion of DNA synthesis to a mitotic checkpoint. Genetics. 143: 165-74. PMID 8722772 |
0.301 |
|
| 1996 |
Kiyokawa H, Kineman RD, Manova-Todorova KO, Soares VC, Hoffman ES, Ono M, Khanam D, Hayday AC, Frohman LA, Koff A. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell. 85: 721-32. PMID 8646780 DOI: 10.1016/S0092-8674(00)81238-6 |
0.474 |
|
| 1996 |
Hoffman ES, Passoni L, Crompton T, Leu TM, Schatz DG, Koff A, Owen MJ, Hayday AC. Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo. Genes & Development. 10: 948-62. PMID 8608942 DOI: 10.1101/Gad.10.8.948 |
0.376 |
|
| 1995 |
Koff A, Polyak K. p27KIP1, an inhibitor of cyclin-dependent kinases Progress in Cell Cycle Research. 1: 141-147. PMID 9552359 DOI: 10.1007/978-1-4615-1809-9_11 |
0.533 |
|
| 1995 |
Fan Z, Lu Y, Wu X, DeBlasio A, Koff A, Mendelsohn J. Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition Journal of Cell Biology. 131: 235-242. PMID 7559780 DOI: 10.1083/Jcb.131.1.235 |
0.402 |
|
| 1994 |
Polyak K, Kato JY, Solomon MJ, Sherr CJ, Massague J, Roberts JM, Koff A. P27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest Genes and Development. 8: 9-22. PMID 8288131 DOI: 10.1101/Gad.8.1.9 |
0.532 |
|
| 1994 |
Firpo EJ, Koff A, Solomon MJ, Roberts JM. Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes Molecular and Cellular Biology. 14: 4889-4901. PMID 7516474 |
0.436 |
|
| 1993 |
Koff A, Ohtsuki M, Polyak K, Roberts JM, Massagué J. Negative regulation of G1 in mammalian cells: Inhibition of cyclin E-dependent kinase by TGF-β Science. 260. PMID 8475385 DOI: 10.1126/Science.8475385 |
0.354 |
|
| 1992 |
Koff A, Giordano A, Desai D, Yamashita K, Harper JW, Elledge S, Nishimoto T, Morgan DO, Franza BR, Roberts JM. Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science (New York, N.Y.). 257: 1689-94. PMID 1388288 DOI: 10.1126/Science.1388288 |
0.452 |
|
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