| Year |
Citation |
Score |
| 2023 |
Cheng N, Trejo J. An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses. The Journal of Biological Chemistry. 105370. PMID 37865315 DOI: 10.1016/j.jbc.2023.105370 |
0.477 |
|
| 2023 |
Birch CA, Wedegaertner H, Orduña-Castillo LB, Gonzalez Ramirez ML, Qin H, Trejo J. Endothelial APC/PAR1 distinctly regulates cytokine-induced pro-inflammatory VCAM-1 expression. Frontiers in Molecular Biosciences. 10: 1211597. PMID 37692066 DOI: 10.3389/fmolb.2023.1211597 |
0.495 |
|
| 2023 |
Wedegaertner H, Bosompra O, Kufareva I, Trejo J. Divergent regulation of α-arrestin ARRDC3 function by ubiquitination. Molecular Biology of the Cell. mbcE23020055. PMID 37223976 DOI: 10.1091/mbc.E23-02-0055 |
0.364 |
|
| 2022 |
Molinar-Inglis O, Wozniak JM, Grimsey NJ, Orduña-Castillo L, Cheng N, Lin Y, Gonzalez Ramirez ML, Birch CA, Lapek JD, Gonzalez DJ, Trejo J. Phosphoproteomic analysis of thrombin- and p38 MAPK-regulated signaling networks in endothelial cells. The Journal of Biological Chemistry. 101801. PMID 35257745 DOI: 10.1016/j.jbc.2022.101801 |
0.458 |
|
| 2021 |
Molinar-Inglis O, Birch CA, Nicholas D, Orduña-Castillo L, Cisneros-Aguirre M, Patwardhan A, Chen B, Grimsey NJ, Coronel LJ, Lin H, Gomez Menzies PK, Lawson MA, Patel HH, Trejo J. aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34873055 DOI: 10.1073/pnas.2106623118 |
0.439 |
|
| 2021 |
Wedegaertner H, Pan WA, Gonzalez CC, Gonzalez DJ, Trejo J. The α-arrestin ARRDC3 is an Emerging Multifunctional Adaptor Protein in Cancer. Antioxidants & Redox Signaling. PMID 34465145 DOI: 10.1089/ars.2021.0193 |
0.405 |
|
| 2021 |
Arakaki AKS, Pan WA, Wedegaertner H, Roca-Mercado I, Chinn L, Gujral TS, Trejo J. α-arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis. Journal of Cell Science. PMID 33722977 DOI: 10.1242/jcs.254888 |
0.416 |
|
| 2021 |
Patwardhan A, Cheng N, Trejo J. Post-Translational Modifications of G Protein-Coupled Receptors Control Cellular Signaling Dynamics in Space and Time. Pharmacological Reviews. 73: 120-151. PMID 33268549 DOI: 10.1124/pharmrev.120.000082 |
0.499 |
|
| 2021 |
Birch CA, Molinar-Inglis O, Trejo J. Subcellular hot spots of GPCR signaling promote vascular inflammation. Current Opinion in Endocrine and Metabolic Research. 16: 37-42. PMID 32838054 DOI: 10.1016/J.Coemr.2020.07.011 |
0.574 |
|
| 2020 |
Zhou X, Zhong Y, Molinar-Inglis O, Kunkel MT, Chen M, Sun T, Zhang J, Shyy JY, Trejo J, Newton AC, Zhang J. Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus. Nature Communications. 11: 6088. PMID 33257668 DOI: 10.1038/s41467-020-19937-w |
0.308 |
|
| 2020 |
Nicholas DA, Knight VS, Tonsfeldt KJ, Terasaka T, Molinar-Inglis O, Stephens SBZ, Trejo J, Kauffman AS, Mellon PL, Lawson MA. GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes. Scientific Reports. 10: 13063. PMID 32747664 DOI: 10.1038/S41598-020-69913-Z |
0.351 |
|
| 2020 |
Keyes J, Ganesan A, Molinar-Inglis O, Hamidzadeh A, Zhang J, Ling M, Trejo J, Levchenko A, Zhang J. Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics. Elife. 9. PMID 32452765 DOI: 10.7554/Elife.57410 |
0.498 |
|
| 2020 |
Lin Y, Wozniak JM, Grimsey NJ, Girada S, Patwardhan A, Molinar-Inglis O, Smith TH, Lapek JD, Gonzalez DJ, Trejo J. Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function. Proceedings of the National Academy of Sciences of the United States of America. PMID 32071217 DOI: 10.1073/Pnas.1917295117 |
0.592 |
|
| 2020 |
Keyes J, Ganesan A, Molinar-Inglis O, Hamidzadeh A, Zhang J, Ling M, Trejo J, Levchenko A, Zhang J. Author response: Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics Elife. DOI: 10.7554/Elife.57410.Sa2 |
0.37 |
|
| 2020 |
Arakaki AKS, Pan W, Wedegaertner H, Trejo J. Abstract A16: The α-arrestin ARRDC3 functions as a metastasis suppressor by regulating GPCR activation of the Hippo pathway Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-A16 |
0.491 |
|
| 2020 |
Birch CA, Molinar-Inglis O, Lin Y, Trejo J. Role of Protease‐activated receptors in Activated protein C‐mediated anti‐inflammatory responses in endothelial cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07469 |
0.544 |
|
| 2020 |
Ramirez MLG, Lin Y, Molinar-Inglis O, Birch C, Trejo J. G‐protein coupled receptor kinases’ (GRKs) role in APC/PAR1‐induced endothelial cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07442 |
0.492 |
|
| 2020 |
Molinar-Inglis O, Zhang L, Nicholas D, Chen B, Cisneros M, Grimsey NJ, Coronel LJ, Lin Y, Rada C, Chi N, Lawson MA, Trejo J. Integration of GPCR‐induced endothelial cytoprotection signaling by β‐arrestin‐2 The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04881 |
0.373 |
|
| 2020 |
Lin Y, Wozniak J, Grimsey N, Girada S, Patwardan A, Molinar-Inglis O, Smith T, Lapek J, Gonzalez D, Trejo J. Phospho‐proteomic Analysis of Protease‐activated Receptor‐1 Biased Signaling Reveals Novel Modulators of Endothelial Barrier Function The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04784 |
0.384 |
|
| 2020 |
Garcia A, Molinar-Inglis O, Nicholas D, Keyes J, Adame J, Cisneros M, Lawson M, Zhang J, Trejo J. Improved fractionation method demonstrates phosphorylated Akt is localized to the cytoplasm in LβT2 cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04608 |
0.314 |
|
| 2020 |
Arakaki AKS, Pan W, Trejo J. Regulation of GPCR activation of the Hippo pathway in metastatic breast cancer The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04285 |
0.365 |
|
| 2020 |
Wedegaertner H, Pan W, Trejo J. Regulation of alpha‐Arrestin Function in G Protein‐Coupled Receptor Signaling and Trafficking The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02800 |
0.583 |
|
| 2020 |
Patwardhan A, Cheng N, Trejo J. An siRNA screen for endothelial PAR1‐specific deubiquitinases regulating p38 inflammatory signaling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02608 |
0.356 |
|
| 2020 |
Pan W, Arakaki A, Wedegaertner H, Kufareva I, Trejo J. a‐arrestin ARRDC3 is a Multifunctional Adaptor That Regulates G Protein‐Coupled Receptor Signaling and Breast Cancer Invasion The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02390 |
0.479 |
|
| 2020 |
Keyes J, Ganesan A, Molinar-Inglis O, Hamidzadeh A, Ling M, Trejo J, Levchenko A, Zhang J. Signaling Diversity Enabled by Rap1 and cAMP/PKA‐Regulated Plasma Membrane ERK with Distinct Temporal Dynamics The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00680 |
0.354 |
|
| 2019 |
Grimsey NJ, Lin Y, Narala R, Rada CC, Mejia-Pena H, Trejo J. G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2 and TAB1-TAB3 dependent pathway in endothelial cells. The Journal of Biological Chemistry. PMID 30760523 DOI: 10.1074/Jbc.Ra119.007495 |
0.516 |
|
| 2019 |
Bunnett N, DeFea K, Hamilton J, Hollenberg MD, Ramachandran R, Trejo J. Proteinase-activated receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f59/2019.4 |
0.538 |
|
| 2018 |
Dores MR, Trejo J. Endo-lysosomal Sorting of G Protein-coupled Receptors by Ubiquitin: Diverse Pathways for GPCR Destruction and Beyond. Traffic (Copenhagen, Denmark). PMID 30353650 DOI: 10.1111/Tra.12619 |
0.641 |
|
| 2018 |
Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek J, Gonzalez DJ, Handel TM, Zhang J, Trejo J. A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling. Cell Reports. 24: 3312-3323.e5. PMID 30232011 DOI: 10.1016/J.Celrep.2018.08.061 |
0.619 |
|
| 2018 |
Arakaki AKS, Pan WA, Trejo J. GPCRs in Cancer: Protease-Activated Receptors, Endocytic Adaptors and Signaling. International Journal of Molecular Sciences. 19. PMID 29954076 DOI: 10.3390/Ijms19071886 |
0.558 |
|
| 2018 |
Kroeger H, Grimsey N, Paxman R, Chiang WC, Plate L, Jones Y, Shaw PX, Trejo J, Tsang SH, Powers E, Kelly JW, Wiseman RL, Lin JH. The unfolded protein response regulator ATF6 promotes mesodermal differentiation. Science Signaling. 11. PMID 29440509 DOI: 10.1126/Scisignal.Aan5785 |
0.359 |
|
| 2018 |
Arakaki AKS, Pan WA, Lin H, Trejo J. -The a-arrestin ARRDC3 suppresses breast carcinoma invasion by regulating G protein-coupled receptor lysosomal sorting and signaling. The Journal of Biological Chemistry. PMID 29348172 DOI: 10.1074/Jbc.Ra117.001516 |
0.516 |
|
| 2017 |
Smith TH, Li JG, Dores MR, Trejo J. Protease-activated receptor-4 and P2Y12 Dimerize, Co-Internalize and Activate Akt Signaling via Endosomal Recruitment of β-arrestin. The Journal of Biological Chemistry. PMID 28652403 DOI: 10.1074/Jbc.M117.782359 |
0.607 |
|
| 2016 |
Hamilton JR, Trejo J. Challenges and Opportunities in Protease-Activated Receptor Drug Development. Annual Review of Pharmacology and Toxicology. PMID 27618736 DOI: 10.1146/Annurev-Pharmtox-011613-140016 |
0.504 |
|
| 2016 |
Smith TH, Coronel LJ, Li JG, Dores MR, Nieman MT, Trejo J. Protease-activated Receptor-4 Signaling and Trafficking Is Regulated by the Clathrin Adaptor Protein Complex-2 Independent of β-arrestins. The Journal of Biological Chemistry. PMID 27402844 DOI: 10.1074/Jbc.M116.729285 |
0.672 |
|
| 2016 |
Dores MR, Grimsey NJ, Mendez F, Trejo J. ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif. Plos One. 11: e0157587. PMID 27301021 DOI: 10.1371/Journal.Pone.0157587 |
0.626 |
|
| 2016 |
Grimsey NJ, Trejo J. Integration of endothelial protease-activated receptor-1 inflammatory signaling by ubiquitin. Current Opinion in Hematology. PMID 26845544 DOI: 10.1097/Moh.0000000000000232 |
0.523 |
|
| 2016 |
Grimsey NJ, Coronel LJ, Cordova IC, Trejo J. Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins. The Journal of Biological Chemistry. 291: 2223-36. PMID 26635365 DOI: 10.1074/Jbc.M115.702993 |
0.681 |
|
| 2015 |
Dores MR, Lin H, Grimsey N, Mendez F, Trejo J. The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein-coupled receptor lysosomal sorting. Molecular Biology of the Cell. PMID 26490116 DOI: 10.1091/Mbc.E15-05-0284 |
0.626 |
|
| 2015 |
Grimsey NJ, Aguilar B, Smith TH, Le P, Soohoo AL, Puthenveedu MA, Nizet V, Trejo J. Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes. The Journal of Cell Biology. PMID 26391660 DOI: 10.1083/Jcb.201504007 |
0.495 |
|
| 2015 |
Dores MR, Trejo J. GPCR sorting at multivesicular endosomes. Methods in Cell Biology. 130: 319-32. PMID 26360043 DOI: 10.1016/Bs.Mcb.2015.05.006 |
0.596 |
|
| 2015 |
Soto AG, Smith TH, Chen B, Bhattacharya S, Cordova IC, Kenakin T, Vaidehi N, Trejo J. N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias. Proceedings of the National Academy of Sciences of the United States of America. PMID 26100877 DOI: 10.1073/Pnas.1508838112 |
0.63 |
|
| 2015 |
Chen B, Soto AG, Coronel LJ, Goss A, van Ryn J, Trejo J. Characterization of thrombin-bound dabigatran effects on protease-activated receptor-1 expression and signaling in vitro. Molecular Pharmacology. 88: 95-105. PMID 25934730 DOI: 10.1124/Mol.114.096446 |
0.539 |
|
| 2015 |
Trejo J. Exploring GPCR Biased Signaling from inside and outside the Cell The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.101.1 |
0.651 |
|
| 2014 |
Dores MR, Trejo J. Atypical regulation of G protein-coupled receptor intracellular trafficking by ubiquitination. Current Opinion in Cell Biology. 27: 44-50. PMID 24680429 DOI: 10.1016/J.Ceb.2013.11.004 |
0.615 |
|
| 2014 |
Kawamura T, Stephens B, Qin L, Yin X, Dores MR, Smith TH, Grimsey N, Abagyan R, Trejo J, Kufareva I, Fuster MM, Salanga CL, Handel TM. A general method for site specific fluorescent labeling of recombinant chemokines. Plos One. 9: e81454. PMID 24489642 DOI: 10.1371/Journal.Pone.0081454 |
0.479 |
|
| 2014 |
Grimsey N, Lin H, Trejo J. Endosomal signaling by protease-activated receptors. Methods in Enzymology. 535: 389-401. PMID 24377935 DOI: 10.1016/B978-0-12-397925-4.00022-5 |
0.662 |
|
| 2014 |
Chen B, Siderovski DP, Neubig RR, Lawson MA, Trejo J. Regulation of protease-activated receptor 1 signaling by the adaptor protein complex 2 and R4 subfamily of regulator of G protein signaling proteins. The Journal of Biological Chemistry. 289: 1580-91. PMID 24297163 DOI: 10.1074/Jbc.M113.528273 |
0.639 |
|
| 2014 |
Canto I, Grimsey N, Trejo J. Palmitoylation is required for activated PAR1 ubiquitination and p38 MAPK signaling (1066.16) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1066.16 |
0.657 |
|
| 2014 |
Grimsey N, Smith T, Le P, Trejo J. Ubiquitination of PAR1 nucleates a non-canonical p38 signaling pathway to regulate thrombin-induced vascular leakage (1066.15) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1066.15 |
0.542 |
|
| 2013 |
Lin H, Liu AP, Smith TH, Trejo J. Cofactoring and dimerization of proteinase-activated receptors. Pharmacological Reviews. 65: 1198-213. PMID 24064459 DOI: 10.1124/Pr.111.004747 |
0.641 |
|
| 2013 |
Gilliland CT, Salanga CL, Kawamura T, Trejo J, Handel TM. The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, β-arrestin-mediated internalization. The Journal of Biological Chemistry. 288: 32194-210. PMID 24056371 DOI: 10.1074/Jbc.M113.503797 |
0.616 |
|
| 2013 |
Canto I, Trejo J. Palmitoylation of protease-activated receptor-1 regulates adaptor protein complex-2 and -3 interaction with tyrosine-based motifs and endocytic sorting. The Journal of Biological Chemistry. 288: 15900-12. PMID 23580642 DOI: 10.1074/Jbc.M113.469866 |
0.627 |
|
| 2013 |
Lin H, Trejo J. Transactivation of the PAR1-PAR2 heterodimer by thrombin elicits β-arrestin-mediated endosomal signaling. The Journal of Biological Chemistry. 288: 11203-15. PMID 23476015 DOI: 10.1074/Jbc.M112.439950 |
0.598 |
|
| 2013 |
Marchese A, Trejo J. Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling. Cellular Signalling. 25: 707-16. PMID 23201781 DOI: 10.1016/J.Cellsig.2012.11.024 |
0.611 |
|
| 2012 |
Dores MR, Paing MM, Lin H, Montagne WA, Marchese A, Trejo J. AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway. Molecular Biology of the Cell. 23: 3612-23. PMID 22833563 DOI: 10.1091/Mbc.E12-03-0251 |
0.838 |
|
| 2012 |
Dores MR, Trejo J. Ubiquitination of G protein-coupled receptors: functional implications and drug discovery. Molecular Pharmacology. 82: 563-70. PMID 22700696 DOI: 10.1124/Mol.112.079418 |
0.594 |
|
| 2012 |
Canto I, Soh UJK, Trejo J. Allosteric modulation of protease-activated receptor signaling Mini-Reviews in Medicinal Chemistry. 12: 804-811. PMID 22681248 DOI: 10.2174/138955712800959116 |
0.64 |
|
| 2012 |
Dores MR, Chen B, Lin H, Soh UJ, Paing MM, Montagne WA, Meerloo T, Trejo J. ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting. The Journal of Cell Biology. 197: 407-19. PMID 22547407 DOI: 10.1083/Jcb.201110031 |
0.832 |
|
| 2012 |
Malik R, Soh UJ, Trejo J, Marchese A. Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling. The Journal of Biological Chemistry. 287: 9013-27. PMID 22275353 DOI: 10.1074/Jbc.M111.336792 |
0.62 |
|
| 2011 |
Soh UJ, Trejo J. Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through β-arrestin and dishevelled-2 scaffolds. Proceedings of the National Academy of Sciences of the United States of America. 108: E1372-80. PMID 22106258 DOI: 10.1073/Pnas.1112482108 |
0.552 |
|
| 2011 |
Chen B, Dores MR, Grimsey N, Canto I, Barker BL, Trejo J. Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals. The Journal of Biological Chemistry. 286: 40760-70. PMID 21965661 DOI: 10.1074/Jbc.M111.299776 |
0.674 |
|
| 2011 |
Grimsey N, Soto AG, Trejo J. Regulation of protease-activated receptor signaling by post-translational modifications. Iubmb Life. 63: 403-11. PMID 21438117 DOI: 10.1002/Iub.442 |
0.643 |
|
| 2010 |
Laroche G, Giguère PM, Roth BL, Trejo J, Siderovski DP. RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling. American Journal of Physiology. Cell Physiology. 299: C654-64. PMID 20573995 DOI: 10.1152/Ajpcell.00441.2009 |
0.519 |
|
| 2010 |
Soh UJ, Dores MR, Chen B, Trejo J. Signal transduction by protease-activated receptors. British Journal of Pharmacology. 160: 191-203. PMID 20423334 DOI: 10.1111/J.1476-5381.2010.00705.X |
0.679 |
|
| 2010 |
Soto AG, Trejo J. N-linked glycosylation of protease-activated receptor-1 second extracellular loop: a critical determinant for ligand-induced receptor activation and internalization. The Journal of Biological Chemistry. 285: 18781-93. PMID 20368337 DOI: 10.1074/Jbc.M110.111088 |
0.589 |
|
| 2010 |
Trejo J. Dysregulation of G protein-coupled receptor signaling in cancer Signal Transduction: Pathways, Mechanisms and Diseases. 83-98. DOI: 10.1007/978-3-642-02112-1_5 |
0.521 |
|
| 2009 |
Ricks TK, Trejo J. Phosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization. The Journal of Biological Chemistry. 284: 34444-57. PMID 19815543 DOI: 10.1074/Jbc.M109.048942 |
0.813 |
|
| 2009 |
Russo A, Soh UJ, Trejo J. Proteases display biased agonism at protease-activated receptors: location matters! Molecular Interventions. 9: 87-96. PMID 19401541 DOI: 10.1124/Mi.9.2.8 |
0.736 |
|
| 2009 |
Russo A, Soh UJ, Paing MM, Arora P, Trejo J. Caveolae are required for protease-selective signaling by protease-activated receptor-1. Proceedings of the National Academy of Sciences of the United States of America. 106: 6393-7. PMID 19332793 DOI: 10.1073/Pnas.0810687106 |
0.824 |
|
| 2009 |
Trejo J. Regulation of thrombin receptor signaling Thrombin: Physiology and Disease. 47-61. DOI: 10.1007/978-0-387-09637-7_3 |
0.622 |
|
| 2008 |
Arora P, Cuevas BD, Russo A, Johnson GL, Trejo J. Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion. Oncogene. 27: 4434-45. PMID 18372913 DOI: 10.1038/Onc.2008.84 |
0.644 |
|
| 2008 |
Alam MR, Dixit V, Kang H, Li ZB, Chen X, Trejo J, Fisher M, Juliano RL. Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis. Nucleic Acids Research. 36: 2764-76. PMID 18367474 DOI: 10.1093/Nar/Gkn115 |
0.394 |
|
| 2008 |
Marchese A, Paing MM, Temple BR, Trejo J. G protein-coupled receptor sorting to endosomes and lysosomes. Annual Review of Pharmacology and Toxicology. 48: 601-29. PMID 17995450 DOI: 10.1146/Annurev.Pharmtox.48.113006.094646 |
0.83 |
|
| 2007 |
Bhandari D, Trejo J, Benovic JL, Marchese A. Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4. The Journal of Biological Chemistry. 282: 36971-9. PMID 17947233 DOI: 10.1074/Jbc.M705085200 |
0.56 |
|
| 2007 |
Wolfe BL, Marchese A, Trejo J. Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1. The Journal of Cell Biology. 177: 905-16. PMID 17535965 DOI: 10.1083/Jcb.200610154 |
0.812 |
|
| 2007 |
Traynelis SF, Trejo J. Protease-activated receptor signaling: new roles and regulatory mechanisms. Current Opinion in Hematology. 14: 230-5. PMID 17414212 DOI: 10.1097/Moh.0B013E3280Dce568 |
0.66 |
|
| 2007 |
Wolfe BL, Trejo J. Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis. Traffic (Copenhagen, Denmark). 8: 462-70. PMID 17376169 DOI: 10.1111/J.1600-0854.2007.00551.X |
0.798 |
|
| 2007 |
Arora P, Ricks TK, Trejo J. Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer. Journal of Cell Science. 120: 921-8. PMID 17344429 DOI: 10.1242/Jcs.03409 |
0.812 |
|
| 2006 |
Camerer E, Trejo J. Cryptic messages: is noncoagulant tissue factor reserved for cell signaling? Proceedings of the National Academy of Sciences of the United States of America. 103: 14259-60. PMID 16985001 DOI: 10.1073/Pnas.0606888103 |
0.539 |
|
| 2006 |
Dho SE, Trejo J, Siderovski DP, McGlade CJ. Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of numb association with the cortical membrane. Molecular Biology of the Cell. 17: 4142-55. PMID 16837553 DOI: 10.1091/Mbc.E06-02-0097 |
0.354 |
|
| 2006 |
Paing MM, Johnston CA, Siderovski DP, Trejo J. Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. Molecular and Cellular Biology. 26: 3231-42. PMID 16581796 DOI: 10.1128/Mcb.26.8.3231-3242.2006 |
0.842 |
|
| 2006 |
Gullapalli A, Wolfe BL, Griffin CT, Magnuson T, Trejo J. An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins. Molecular Biology of the Cell. 17: 1228-38. PMID 16407403 DOI: 10.1091/Mbc.E05-09-0899 |
0.776 |
|
| 2006 |
Morris DR, Ding Y, Ricks TK, Gullapalli A, Wolfe BL, Trejo J. Protease-activated receptor-2 is essential for factor VIIa and Xa-induced signaling, migration, and invasion of breast cancer cells. Cancer Research. 66: 307-14. PMID 16397244 DOI: 10.1158/0008-5472.Can-05-1735 |
0.814 |
|
| 2005 |
Urs NM, Jones KT, Salo PD, Severin JE, Trejo J, Radhakrishna H. A requirement for membrane cholesterol in the beta-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors. Journal of Cell Science. 118: 5291-304. PMID 16263766 DOI: 10.1242/Jcs.02634 |
0.42 |
|
| 2005 |
Trejo J. Internal PDZ ligands: novel endocytic recycling motifs for G protein-coupled receptors. Molecular Pharmacology. 67: 1388-90. PMID 15713849 DOI: 10.1124/Mol.105.011288 |
0.615 |
|
| 2005 |
Stalheim L, Ding Y, Gullapalli A, Paing MM, Wolfe BL, Morris DR, Trejo J. Multiple independent functions of arrestins in the regulation of protease-activated receptor-2 signaling and trafficking. Molecular Pharmacology. 67: 78-87. PMID 15475570 DOI: 10.1124/Mol.104.006072 |
0.834 |
|
| 2004 |
Paing MM, Temple BR, Trejo J. A tyrosine-based sorting signal regulates intracellular trafficking of protease-activated receptor-1: multiple regulatory mechanisms for agonist-induced G protein-coupled receptor internalization. The Journal of Biological Chemistry. 279: 21938-47. PMID 15023990 DOI: 10.1074/Jbc.M401672200 |
0.844 |
|
| 2004 |
Gullapalli A, Garrett TA, Paing MM, Griffin CT, Yang Y, Trejo J. A role for sorting nexin 2 in epidermal growth factor receptor down-regulation: evidence for distinct functions of sorting nexin 1 and 2 in protein trafficking. Molecular Biology of the Cell. 15: 2143-55. PMID 14978220 DOI: 10.1091/Mbc.E03-09-0711 |
0.802 |
|
| 2004 |
Booden MA, Eckert LB, Der CJ, Trejo J. Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion. Molecular and Cellular Biology. 24: 1990-9. PMID 14966279 DOI: 10.1128/Mcb.24.5.1990-1999.2004 |
0.477 |
|
| 2004 |
Chen CH, Paing MM, Trejo J. Termination of protease-activated receptor-1 signaling by beta-arrestins is independent of receptor phosphorylation. The Journal of Biological Chemistry. 279: 10020-31. PMID 14699102 DOI: 10.1074/Jbc.M310590200 |
0.833 |
|
| 2003 |
Trejo J. Protease-activated receptors: new concepts in regulation of G protein-coupled receptor signaling and trafficking. The Journal of Pharmacology and Experimental Therapeutics. 307: 437-42. PMID 12966163 DOI: 10.1124/Jpet.103.052100 |
0.674 |
|
| 2002 |
Wang Y, Zhou Y, Szabo K, Haft CR, Trejo J. Down-regulation of protease-activated receptor-1 is regulated by sorting nexin 1. Molecular Biology of the Cell. 13: 1965-76. PMID 12058063 DOI: 10.1091/Mbc.E01-11-0131 |
0.646 |
|
| 2002 |
Paing MM, Stutts AB, Kohout TA, Lefkowitz RJ, Trejo J. beta -Arrestins regulate protease-activated receptor-1 desensitization but not internalization or Down-regulation. The Journal of Biological Chemistry. 277: 1292-300. PMID 11694535 DOI: 10.1074/Jbc.M109160200 |
0.8 |
|
| 2001 |
Pons S, Trejo JL, Martínez-Morales JR, Martí E. Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation Development. 128: 1481-1492. PMID 11290288 |
0.319 |
|
| 2001 |
Trejo JL, Pons S. Phosphatidylinositol 3-OH kinase regulatory subunits are differentially expressed during development of the rat cerebellum Journal of Neurobiology. 47: 39-50. PMID 11257612 DOI: 10.1002/neu.1014 |
0.338 |
|
| 2000 |
Trejo J, Altschuler Y, Fu HW, Mostov KE, Coughlin SR. Protease-activated receptor-1 down-regulation: a mutant HeLa cell line suggests novel requirements for PAR1 phosphorylation and recruitment to clathrin-coated pits. The Journal of Biological Chemistry. 275: 31255-65. PMID 10893235 DOI: 10.1074/Jbc.M003770200 |
0.66 |
|
| 1999 |
Kahn ML, Diacovo TG, Bainton DF, Lanza F, Trejo J, Coughlin SR. Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and Do not exhibit a Bernard-Soulier phenotype. Blood. 94: 4112-21. PMID 10590056 DOI: 10.1182/Blood.V94.12.4112 |
0.318 |
|
| 1999 |
Trejo J, Coughlin SR. The cytoplasmic tails of protease-activated receptor-1 and substance P receptor specify sorting to lysosomes versus recycling. The Journal of Biological Chemistry. 274: 2216-24. PMID 9890984 DOI: 10.1074/Jbc.274.4.2216 |
0.59 |
|
| 1998 |
Trejo J, Hammes SR, Coughlin SR. Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting. Proceedings of the National Academy of Sciences of the United States of America. 95: 13698-702. PMID 9811863 DOI: 10.1073/Pnas.95.23.13698 |
0.679 |
|
| 1996 |
Shapiro MJ, Trejo J, Zeng D, Coughlin SR. Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization. The Journal of Biological Chemistry. 271: 32874-80. PMID 8955127 DOI: 10.1074/Jbc.271.51.32874 |
0.637 |
|
| 1996 |
Brown JL, Stowers L, Baer M, Trejo J, Coughlin S, Chant J. Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway. Current Biology : Cb. 6: 598-605. PMID 8805275 DOI: 10.1016/S0960-9822(02)00546-8 |
0.498 |
|
| 1996 |
Trejo J, Connolly AJ, Coughlin SR. The cloned thrombin receptor is necessary and sufficient for activation of mitogen-activated protein kinase and mitogenesis in mouse lung fibroblasts. Loss of responses in fibroblasts from receptor knockout mice. The Journal of Biological Chemistry. 271: 21536-41. PMID 8702939 DOI: 10.1074/Jbc.271.35.21536 |
0.523 |
|
| 1992 |
Trejo J, Chambard JC, Karin M, Brown JH. Biphasic Increase in c-jun mRNA Is Required for Induction of AP-1-Mediated Gene Transcription: Differential Effects of Muscarinic and Thrombin Receptor Activation Molecular and Cellular Biology. 12: 4742-4750. PMID 1328861 DOI: 10.1128/Mcb.12.10.4742 |
0.354 |
|
| 1990 |
Brown JH, Trilivas I, Trejo J, Martinson E. Multiple pathways for signal transduction through the muscarinic cholinergic receptor Progress in Brain Research. 84: 21-29. PMID 2267298 DOI: 10.1016/S0079-6123(08)60885-7 |
0.522 |
|
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