Christopher M. Hickey
Affiliations: | Yale University, New Haven, CT |
Area:
Cell Biology, BiochemistryWebsite:
http://medicine.yale.edu/lab/hochstrasser/people/christopher_hickey.profileGoogle:
"Christopher Hickey"Bio:
http://gradworks.umi.com/34/03/3403101.html
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| William Wickner | grad student | 2010 | Dartmouth | |
| (Mechanisms of Rab- and Rab effector-dependent membrane tethering, docking, and fusion.) | ||||
| Mark W. Hochstrasser | post-doc | 2010- | Yale | |
Children
Sign in to add trainee| Eric J Wright | research scientist | 2022- | (Chemistry Tree) |
| Huda Zahid | research scientist | 2022- | (Chemistry Tree) |
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Publications
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| Breckel CA, Johnson ZM, Hickey CM, et al. (2024) Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1. Scientific Reports. 14: 2048 |
| Hickey CM, Breckel C, Zhang M, et al. (2021) Protein quality control degron-containing substrates are differentially targeted in the cytoplasm and nucleus by ubiquitin ligases. Genetics. 217: 1-19 |
| Budenholzer L, Breckel C, Hickey CM, et al. (2020) The Sts1 nuclear import adaptor uses a noncanonical bipartite NLS and is directly degraded by the proteasome. Journal of Cell Science |
| Hickey CM, Xie Y, Hochstrasser M. (2018) DNA Binding by the MATα2 Transcription Factor Controls its Access to Alternative Ubiquitin-modification Pathways. Molecular Biology of the Cell |
| Hickey CM. (2016) Degradation elements coincide with cofactor binding sites in a short-lived transcription factor. Cellular Logistics. 6: e1157664 |
| Gillies J, Hickey CM, Su D, et al. (2016) SUMO Pathway Modulation of Regulatory Protein Binding at the Ribosomal DNA Locus in Saccharomyces cerevisiae. Genetics |
| Hickey CM, Hochstrasser M. (2015) STUbL-mediated degradation of the transcription factor MATα2 requires degradation elements that coincide with corepressor binding sites. Molecular Biology of the Cell. 26: 3401-12 |
| Hickey CM, Wilson NR, Hochstrasser M. (2012) Function and regulation of SUMO proteases. Nature Reviews. Molecular Cell Biology. 13: 755-66 |
| Hickey CM, Wickner W. (2010) HOPS initiates vacuole docking by tethering membranes before trans-SNARE complex assembly. Molecular Biology of the Cell. 21: 2297-305 |
| Stroupe C, Hickey CM, Mima J, et al. (2009) Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components. Proceedings of the National Academy of Sciences of the United States of America. 106: 17626-33 |