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Paul C. Norris, Ph.D. - Publications

Affiliations: 
2013 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Biochemistry: phospholipase A2, signal transduction in macrophages, lipid maps, prostaglandin regulation, mass spec of lipids and proteins
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kooij G, Derada Troletti C, Leuti A, Norris PC, Riley I, Albanese M, Ruggieri S, Libreros S, van der Pol SMA, van Het Hof B, Schell Y, Guerrera G, Buttari F, Mercuri NB, Centonze D, et al. Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction. Haematologica. PMID 31780628 DOI: 10.3324/Haematol.2019.219519  0.406
2019 Norris PC, Libreros S, Serhan CN. Resolution metabolomes activated by hypoxic environment. Science Advances. 5: eaax4895. PMID 31681846 DOI: 10.1126/Sciadv.Aax4895  0.432
2019 Chiang N, Libreros S, Norris PC, de la Rosa X, Serhan CN. Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions. The Journal of Clinical Investigation. PMID 31657786 DOI: 10.1172/Jci129448  0.374
2019 Levy BD, Abdulnour RE, Tavares A, Brüggemann TR, Norris PC, Bai Y, Ai X, Serhan CN. Cys-LTs' Pro-phlogistic Lung Actions Are Regulated by Cys-Maresins. The Journal of Allergy and Clinical Immunology. PMID 31622689 DOI: 10.1016/J.Jaci.2019.09.028  0.361
2019 Jouvene CC, Shay AE, Soens MA, Norris PC, Haeggström JZ, Serhan CN. Biosynthetic metabolomes of cysteinyl-containing immunoresolvents. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201902003R. PMID 31589826 DOI: 10.1096/Fj.201902003R  0.367
2019 Becker F, Romero E, Goetzmann J, Hasselschwert DL, Dray B, Vanchiere J, Fontenot J, Yun JW, Norris PC, White L, Musso M, Serhan CN, Alexander JS, Gavins FNE. Endogenous Specialized Proresolving Mediator Profiles in a Novel Experimental Model of Lymphatic Obstruction and Intestinal Inflammation in African Green Monkeys. The American Journal of Pathology. 189: 1953-1972. PMID 31547920 DOI: 10.1016/J.Ajpath.2019.05.013  0.381
2019 Cherpokova D, Jouvene CC, Libreros S, DeRoo E, Chu L, de la Rosa X, Norris P, Wagner DD, Serhan CN. Resolvin D4 attenuates the severity of pathological thrombosis in mice. Blood. PMID 31300403 DOI: 10.1182/Blood.2018886317  0.389
2019 Gilligan MM, Gartung A, Sulciner ML, Norris PC, Sukhatme VP, Bielenberg DR, Huang S, Kieran MW, Serhan CN, Panigrahy D. Aspirin-triggered proresolving mediators stimulate resolution in cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30862734 DOI: 10.1073/Pnas.1804000116  0.4
2019 Davis-Porada J, Serhan C, Norris P, Lipsky P, Salmon J. 3 Polyunsaturated fatty acids (PUFAs) and specialized pro-resolving mediators (SPMs) are decreased in plasma and serum from SLE patients compared to healthy controls Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.3  0.335
2019 Davis-Porada J, Serhan C, Norris P, Lipsky P, Salmon JE. Thu0279 Polyunsaturated Fatty Acids (Pufas) And Specialized Pro-Resolving Mediators (Spms) Are Decreased In Plasma And Serum From Sle Patients Compared To Healthy Controls Annals of the Rheumatic Diseases. 78: 417-418. DOI: 10.1136/Annrheumdis-2019-Eular.2126  0.333
2018 Norris PC, Skulas-Ray AC, Riley I, Richter CK, Kris-Etherton PM, Jensen GL, Serhan CN, Maddipati KR. Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation. Scientific Reports. 8: 18050. PMID 30575798 DOI: 10.1038/S41598-018-36679-4  0.364
2018 Matte A, Recchiuti A, Federti E, Koehl B, Mintz T, El Nemer W, Tharaux PL, Brousse V, Andolfo I, Lamolinara A, Weinberg O, Siciliano A, Norris PC, Riley IR, Iolascon A, et al. Resolution of sickle cell disease associated inflammation and tissue damage with 17R-Resolvin D1. Blood. PMID 30404812 DOI: 10.1182/Blood-2018-07-865378  0.441
2018 Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proceedings of the National Academy of Sciences of the United States of America. PMID 30139917 DOI: 10.1073/Pnas.1806077115  0.379
2018 Gregus AM, Buczynski MW, Dumlao DS, Norris PC, Rai G, Simeonov A, Maloney DJ, Jadhav A, Xu Q, Wei SC, Fitzsimmons BL, Dennis EA, Yaksh TL. Inhibition of Spinal 15-LOX-1 Attenuates TLR4-Dependent, NSAID-Unresponsive Hyperalgesia in Male Rats. Pain. PMID 30130298 DOI: 10.1097/J.Pain.0000000000001373  0.505
2018 Sorokin AV, Norris PC, English JT, Dey AK, Chaturvedi A, Baumer Y, Silverman J, Playford MP, Serhan CN, Mehta NN. Identification of proresolving and inflammatory lipid mediators in human psoriasis. Journal of Clinical Lipidology. PMID 29730187 DOI: 10.1016/J.Jacl.2018.03.091  0.436
2018 de la Rosa X, Norris PC, Chiang N, Rodriguez AR, Spur BW, Serhan CN. Identification and Complete Stereochemical Assignments of the New Resolvin Conjugates in Tissue Regeneration in Human Tissues that Stimulate Proresolving Phagocyte Functions and Tissue Regeneration. The American Journal of Pathology. 188: 950-966. PMID 29571326 DOI: 10.1016/J.Ajpath.2018.01.004  0.371
2018 Norris PC, Serhan CN. Metabololipidomic profiling of functional immunoresolvent clusters and eicosanoids in mammalian tissues. Biochemical and Biophysical Research Communications. PMID 29524409 DOI: 10.1016/J.Bbrc.2018.03.037  0.379
2018 Sham HP, Walker KH, Abdulnour RE, Krishnamoorthy N, Douda DN, Norris PC, Barkas I, Benito-Figueroa S, Colby JK, Serhan CN, Levy BD. 15-epi-Lipoxin A, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia. Journal of Immunology (Baltimore, Md. : 1950). PMID 29523657 DOI: 10.4049/Jimmunol.1602090  0.361
2018 Winkler JW, Libreros S, De La Rosa X, Sansbury BE, Norris PC, Chiang N, Fichtner D, Keyes GS, Wourms N, Spite M, Serhan CN. Structural insights into Resolvin D4 actions and further metabolites via a new total organic synthesis and validation. Journal of Leukocyte Biology. PMID 29377345 DOI: 10.1002/Jlb.3Mi0617-254R  0.344
2018 Werz O, Gerstmeier J, Libreros S, De la Rosa X, Werner M, Norris PC, Chiang N, Serhan CN. Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity. Nature Communications. 9: 59. PMID 29302056 DOI: 10.1038/S41467-017-02538-5  0.377
2017 Motwani MP, Bennett F, Norris PC, Maini AA, George MJ, Newson J, Henderson A, Hobbs AJ, Tepper M, White B, Serhan CN, MacAllister R, Gilroy DW. Potent anti-inflammatory and pro-resolving effects of anabasum in a human model of self-resolving acute inflammation. Clinical Pharmacology and Therapeutics. PMID 29238967 DOI: 10.1002/Cpt.980  0.415
2017 Sima C, Montero E, Nguyen D, Freire M, Norris P, Serhan CN, Van Dyke TE. ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance. Scientific Reports. 7: 12848. PMID 28993702 DOI: 10.1038/S41598-017-13185-7  0.334
2017 Norris PC, Libreros S, Chiang N, Serhan CN. A cluster of immunoresolvents links coagulation to innate host defense in human blood. Science Signaling. 10. PMID 28765512 DOI: 10.1126/Scisignal.Aan1471  0.327
2017 Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon JS, Shinohara M, Hisata S, Howrylak JA, Suh GY, Ryter SW, Serhan CN, Choi AM. NLRP3 Inflammasome Deficiency Protects Against Microbial Sepsis via Increased Lipoxin B4 Synthesis. American Journal of Respiratory and Critical Care Medicine. PMID 28245134 DOI: 10.1164/Rccm.201604-0892Oc  0.358
2017 English JT, Norris PC, Hodges RR, Dartt DA, Serhan CN. Identification and Profiling of Specialized Pro-Resolving Mediators in Human Tears by Lipid Mediator Metabolomics. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 117: 17-27. PMID 28237084 DOI: 10.1016/J.Plefa.2017.01.004  0.392
2016 Gupta S, Kihara Y, Maurya MR, Norris PC, Dennis EA, Subramaniam S. Computational Modeling of Competitive Metabolism Between ω3- and ω6 Polyunsaturated Fatty Acids in Inflammatory Macrophages. The Journal of Physical Chemistry. B. PMID 27063350 DOI: 10.1021/Acs.Jpcb.6B02036  0.55
2016 Norris PC, Arnardottir H, Sanger JM, Fichtner D, Keyes GS, Serhan CN. Resolvin D3 multi-level proresolving actions are host protective during infection. Prostaglandins, Leukotrienes, and Essential Fatty Acids. PMID 26858146 DOI: 10.1016/J.Plefa.2016.01.001  0.395
2015 Dennis EA, Norris PC. Eicosanoid storm in infection and inflammation. Nature Reviews. Immunology. PMID 26139350 DOI: 10.1038/Nri3859  0.572
2015 Dalli J, Ramon S, Norris PC, Colas RA, Serhan CN. Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2120-36. PMID 25713027 DOI: 10.1096/Fj.14-268441  0.36
2015 Dennis EA, Norris PC. Erratum: Eicosanoid storm in infection and inflammation Nature Reviews Immunology. 15: 724-724. DOI: 10.1038/Nri3928  0.467
2014 Norris PC, Gosselin D, Reichart D, Glass CK, Dennis EA. Phospholipase A2 regulates eicosanoid class switching during inflammasome activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 12746-51. PMID 25139986 DOI: 10.1073/Pnas.1404372111  0.591
2014 Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular Cancer Research : McR. 12: 1677-88. PMID 25063587 DOI: 10.1158/1541-7786.Mcr-14-0397-T  0.477
2014 Norris PC, Dennis EA. A lipidomic perspective on inflammatory macrophage eicosanoid signaling. Advances in Biological Regulation. 54: 99-110. PMID 24113376 DOI: 10.1016/J.Jbior.2013.09.009  0.594
2013 Gregus AM, Dumlao DS, Wei SC, Norris PC, Catella LC, Meyerstein FG, Buczynski MW, Steinauer JJ, Fitzsimmons BL, Yaksh TL, Dennis EA. Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1939-49. PMID 23382512 DOI: 10.1096/Fj.12-217414  0.543
2012 Dumlao DS, Cunningham AM, Wax LE, Norris PC, Hanks JH, Halpin R, Lett KM, Blaho VA, Mitchell WJ, Fritsche KL, Dennis EA, Brown CR. Dietary fish oil substitution alters the eicosanoid profile in ankle joints of mice during Lyme infection. The Journal of Nutrition. 142: 1582-9. PMID 22695969 DOI: 10.3945/Jn.112.157883  0.526
2012 Norris PC, Dennis EA. Omega-3 fatty acids cause dramatic changes in TLR4 and purinergic eicosanoid signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 8517-22. PMID 22586114 DOI: 10.1073/Pnas.1200189109  0.578
2011 Dumlao DS, Buczynski MW, Norris PC, Harkewicz R, Dennis EA. High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines. Biochimica Et Biophysica Acta. 1811: 724-36. PMID 21689782 DOI: 10.1016/J.Bbalip.2011.06.005  0.535
2011 Norris PC, Reichart D, Dumlao DS, Glass CK, Dennis EA. Specificity of eicosanoid production depends on the TLR-4-stimulated macrophage phenotype. Journal of Leukocyte Biology. 90: 563-74. PMID 21653236 DOI: 10.1189/Jlb.0311153  0.549
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