Ying Lai, Ph.D. - Publications

Affiliations: 
2013 Biochemistry, Biophysics, and Molecular Biology Iowa State University, Ames, IA, United States 
Area:
Biochemistry, General Biophysics

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Brunger AT, Choi UB, Lai Y, Leitz J, White KI, Zhou Q. The pre-synaptic fusion machinery. Current Opinion in Structural Biology. 54: 179-188. PMID 30986753 DOI: 10.1016/j.sbi.2019.03.007  0.48
2018 Brunger AT, Choi UB, Lai Y, Leitz J, Zhou Q. Molecular Mechanisms of Fast Neurotransmitter Release. Annual Review of Biophysics. 47: 469-497. PMID 29792815 DOI: 10.1146/annurev-biophys-070816-034117  0.48
2018 Brunger AT, Leitz J, Zhou Q, Choi UB, Lai Y. Ca-Triggered Synaptic Vesicle Fusion Initiated by Release of Inhibition. Trends in Cell Biology. PMID 29706534 DOI: 10.1016/j.tcb.2018.03.004  0.48
2017 Lai Y, Choi UB, Leitz J, Rhee HJ, Lee C, Altas B, Zhao M, Pfuetzner RA, Wang AL, Brose N, Rhee J, Brunger AT. Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18. Neuron. 95: 591-607.e10. PMID 28772123 DOI: 10.1016/j.neuron.2017.07.004  0.48
2017 Gipson P, Fukuda Y, Danev R, Lai Y, Chen DH, Baumeister W, Brunger AT. Morphologies of synaptic protein membrane fusion interfaces. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739947 DOI: 10.1073/pnas.1708492114  0.48
2016 Wang Y, Li L, Hou C, Lai Y, Long J, Liu J, Zhong Q, Diao J. SNARE-mediated membrane fusion in autophagy. Seminars in Cell & Developmental Biology. PMID 27422330 DOI: 10.1016/j.semcdb.2016.07.009  0.48
2016 Malmersjö S, Di Palma S, Diao J, Lai Y, Pfuetzner RA, Wang AL, McMahon MA, Hayer A, Porteus M, Bodenmiller B, Brunger AT, Meyer T. Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion. The Embo Journal. PMID 27402227 DOI: 10.15252/embj.201694071  0.48
2016 Wang C, Zhao C, Li D, Tian Z, Lai Y, Diao J, Liu C. Versatile Structures of α-Synuclein. Frontiers in Molecular Neuroscience. 9: 48. PMID 27378848 DOI: 10.3389/fnmol.2016.00048  0.48
2016 Li L, Hann HW, Wan S, Hann RS, Wang C, Lai Y, Ye X, Evans A, Myers RE, Ye Z, Li B, Xing J, Yang H. Cell-free circulating mitochondrial DNA content and risk of hepatocellular carcinoma in patients with chronic HBV infection. Scientific Reports. 6: 23992. PMID 27063412 DOI: 10.1038/srep23992  0.36
2016 Qiu X, Zhang Y, Liu T, Shen H, Xiao Y, Bourner M, Pratt J, Thompson D, Marathe P, Humphreys WG, Lai Y. Disruption of BSEP Function in HepaRG cells Alters Bile Acid Disposition and is a susceptive factor to Drug-Induced Cholestatic Injury. Molecular Pharmaceutics. PMID 26910619 DOI: 10.1021/acs.molpharmaceut.5b00659  0.48
2016 Shen H, Dai J, Liu T, Cheng Y, Chen W, Freeden C, Zhang Y, Humphreys WG, Marathe P, Lai Y. Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species. The Journal of Pharmacology and Experimental Therapeutics. PMID 26907622 DOI: 10.1124/jpet.116.232066  0.48
2016 Cheng Y, El-Kattan AF, Zhang Y, Ray AS, Lai Y. Involvement of drug transporters in organ toxicity: the fundamental basis to drug discovery and development. Chemical Research in Toxicology. PMID 26889774 DOI: 10.1021/acs.chemrestox.5b00511  0.48
2016 Lai Y, Wang C, Civan JM, Palazzo JP, Ye Z, Hyslop T, Lin J, Myers RE, Li B, Jiang B, Sama A, Xing J, Yang H. Effects of Cancer Stage and Treatment Differences on Racial Disparities in Survival from Colon Cancer: A United States Population-Based Study. Gastroenterology. PMID 26836586 DOI: 10.1053/j.gastro.2016.01.030  0.36
2016 Lai YB, Guo PY, Shao Y, Tang PJ, Zhang Y, Zhang JF. Formation and performances of spinel reaction layers on Co-40Mn coatings under an oxygen pressure of 105 Pa for solid oxide fuel cell interconnect application Vacuum. 130: 14-24. DOI: 10.1016/j.vacuum.2016.04.026  0.4
2016 Zhang Y, Guo P, Shao Y, Lai Y, Zhang J. Preparation and high-temperature performance of Co-10Mn and Co-40Mn alloy coatings for solid oxide fuel cell metal interconnects Journal of Alloys and Compounds. 680: 685-693. DOI: 10.1016/j.jallcom.2016.04.183  0.4
2015 Zhou Q, Lai Y, Bacaj T, Zhao M, Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Brewster AS, Sauter NK, Cohen AE, Soltis SM, Alonso-Mori R, Chollet M, Lemke HT, Pfuetzner RA, et al. Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature. 525: 62-7. PMID 26280336 DOI: 10.1038/nature14975  0.48
2015 Lai Y, Zhao L, Bu B, Lou X, Li D, Ji B, Liu J, Diao J, Shin YK. Lipid molecules influence early stages of yeast SNARE-mediated membrane fusion. Physical Biology. 12: 025003. PMID 25898400 DOI: 10.1088/1478-3975/12/2/025003  0.48
2015 Lai Y, Lou X, Diao J, Shin YK. Molecular origins of synaptotagmin 1 activities on vesicle docking and fusion pore opening. Scientific Reports. 5: 9267. PMID 25791821 DOI: 10.1038/srep09267  0.48
2015 Zhang Y, Diao J, Colbert KN, Lai Y, Pfuetzner RA, Padolina MS, Vivona S, Ressl S, Cipriano DJ, Choi UB, Shah N, Weis WI, Brunger AT. Munc18a does not alter fusion rates mediated by neuronal SNAREs, synaptotagmin, and complexin. The Journal of Biological Chemistry. 290: 10518-34. PMID 25716318 DOI: 10.1074/jbc.M114.630772  0.48
2015 Diao J, Liu R, Rong Y, Zhao M, Zhang J, Lai Y, Zhou Q, Wilz LM, Li J, Vivona S, Pfuetzner RA, Brunger AT, Zhong Q. ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes. Nature. 520: 563-6. PMID 25686604 DOI: 10.1038/nature14147  0.48
2014 Lai Y, Diao J, Cipriano DJ, Zhang Y, Pfuetzner RA, Padolina MS, Brunger AT. Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms. Elife. 3: e03756. PMID 25122624 DOI: 10.7554/eLife.03756  0.48
2014 Lai Y, Kim S, Varkey J, Lou X, Song JK, Diao J, Langen R, Shin YK. Nonaggregated α-synuclein influences SNARE-dependent vesicle docking via membrane binding. Biochemistry. 53: 3889-96. PMID 24884175 DOI: 10.1021/bi5002536  0.48
2014 Lai Y, Lou X, Wang C, Xia T, Tong J. Synaptotagmin 1 and Ca2+ drive trans SNARE zippering. Scientific Reports. 4: 4575. PMID 24694579 DOI: 10.1038/srep04575  0.48
2013 Lai Y, Lou X, Jho Y, Yoon TY, Shin YK. The synaptotagmin 1 linker may function as an electrostatic zipper that opens for docking but closes for fusion pore opening. The Biochemical Journal. 456: 25-33. PMID 24001110 DOI: 10.1042/BJ20130949  0.48
2013 Choi BK, Choi MG, Kim JY, Yang Y, Lai Y, Kweon DH, Lee NK, Shin YK. Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking. Proceedings of the National Academy of Sciences of the United States of America. 110: 4087-92. PMID 23431141 DOI: 10.1073/pnas.1218424110  0.92
2013 Lai Y, Diao J, Liu Y, Ishitsuka Y, Su Z, Schulten K, Ha T, Shin YK. Fusion pore formation and expansion induced by Ca2+ and synaptotagmin 1. Proceedings of the National Academy of Sciences of the United States of America. 110: 1333-8. PMID 23300284 DOI: 10.1073/pnas.1218818110  0.48
2012 Kim JY, Choi BK, Choi MG, Kim SA, Lai Y, Shin YK, Lee NK. Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs. The Embo Journal. 31: 2144-55. PMID 22407297 DOI: 10.1038/emboj.2012.57  0.92
2012 Lai Y, Shin YK. The importance of an asymmetric distribution of acidic lipids for synaptotagmin 1 function as a Ca2+ sensor. The Biochemical Journal. 443: 223-9. PMID 22229667 DOI: 10.1042/BJ20112044  0.92
2010 Diao J, Su Z, Ishitsuka Y, Lu B, Lee KS, Lai Y, Shin YK, Ha T. A single-vesicle content mixing assay for SNARE-mediated membrane fusion. Nature Communications. 1: 54. PMID 20975723 DOI: 10.1038/ncomms1054  0.92
2004 Lan L, Chen W, Lai Y, Suo J, Kong Z, Li C, Lu Y, Zhang Y, Zhao X, Zhang X, Zhang Y, Han B, Cheng J, Xue Y. Monitoring of gene expression profiles and isolation of candidate genes involved in pollination and fertilization in rice ( Oryza sativa L.) with a 10K cDNA microarray. Plant Molecular Biology. 54: 471-87. PMID 15316284 DOI: 10.1023/B:PLAN.0000038254.58491.c7  0.48
2002 Feng Q, Zhang Y, Hao P, Wang S, Fu G, Huang Y, Li Y, Zhu J, Liu Y, Hu X, Jia P, Zhang Y, Zhao Q, Ying K, Yu S, ... ... Lai Y, et al. Sequence and analysis of rice chromosome 4. Nature. 420: 316-20. PMID 12447439 DOI: 10.1038/nature01183  0.48
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