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Jenna L. Jewell, Ph.D. - Publications

Affiliations: 
2010 Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Biochemistry
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, Fu XD, Mills GB, Guan KL. Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling. Cell. 187: 1563-1564. PMID 38490182 DOI: 10.1016/j.cell.2024.02.007  0.553
2023 Jeong MH, Urquhart G, Lewis C, Chi Z, Jewell JL. Inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growth. Jci Insight. 8. PMID 37427586 DOI: 10.1172/jci.insight.158098  0.359
2023 Lama-Sherpa TD, Jeong MH, Jewell JL. Regulation of mTORC1 by the Rag GTPases. Biochemical Society Transactions. 51: 655-664. PMID 36929165 DOI: 10.1042/BST20210038  0.358
2021 Melick CH, Lama-Sherpa TD, Curukovic A, Jewell JL. G-Protein Coupled Receptor Signaling and Mammalian Target of Rapamycin Complex 1 Regulation. Molecular Pharmacology. 101: 181-190. PMID 34965982 DOI: 10.1124/molpharm.121.000302  0.344
2021 Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. AKAP13 couples GPCR signaling to mTORC1 inhibition. Plos Genetics. 17: e1009832. PMID 34673774 DOI: 10.1371/journal.pgen.1009832  0.466
2021 Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL. ArfGAP1 inhibits mTORC1 lysosomal localization and activation. The Embo Journal. e106412. PMID 33988249 DOI: 10.15252/embj.2020106412  0.386
2020 Melick CH, Jewell JL. Regulation of mTORC1 by Upstream Stimuli. Genes. 11. PMID 32854217 DOI: 10.3390/Genes11090989  0.558
2020 Melick CH, Jewell JL. Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors. The Biochemical Journal. 477: 1847-1863. PMID 32347294 DOI: 10.1042/Bcj20190958  0.458
2020 Melick CH, Meng D, Jewell JL. A-kinase anchoring protein 8L interacts with mTORC1 and promotes cell growth. The Journal of Biological Chemistry. PMID 32312749 DOI: 10.1074/Jbc.Ac120.012595  0.476
2020 Meng D, Yang Q, Wang H, Melick CH, Navlani R, Frank AR, Jewell JL. Glutamine and asparagine activate mTORC1 independently of Rag GTPases. The Journal of Biological Chemistry. PMID 32019866 DOI: 10.1074/Jbc.Ac119.011578  0.52
2020 Peng W, Jewell JL. Amino Acid Sensing: Architecture of mTORC1 on the Lysosome Surface. Current Biology : Cb. 30: R89-R91. PMID 31962086 DOI: 10.1016/J.Cub.2019.11.087  0.413
2019 Jewell JL, Fu V, Hong AW, Yu FX, Meng D, Melick CH, Wang H, Lam WM, Yuan HX, Taylor SS, Guan KL. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. Elife. 8. PMID 31112131 DOI: 10.7554/Elife.43038  0.668
2019 Jewell JL, Fu V, Hong AW, Yu F, Meng D, Melick CH, Wang H, Lam WM, Yuan H, Taylor SS, Guan K. Author response: GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor Elife. DOI: 10.7554/Elife.43038.019  0.583
2018 Meng D, Frank AR, Jewell JL. mTOR signaling in stem and progenitor cells. Development (Cambridge, England). 145. PMID 29311260 DOI: 10.1242/Dev.152595  0.354
2017 Nguyen TP, Frank AR, Jewell JL. Amino acid and small GTPase regulation of mTORC1. Cellular Logistics. 7: e1378794. PMID 29296509 DOI: 10.1080/21592799.2017.1378794  0.554
2015 Yuan HX, Wang Z, Yu FX, Li F, Russell RC, Jewell JL, Guan KL. NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition. Genes & Development. 29: 2362-76. PMID 26588989 DOI: 10.1101/Gad.265116.115  0.726
2015 Jewell JL, Flores F, Guan KL. Micro(RNA) managing by mTORC1. Molecular Cell. 57: 575-6. PMID 25699705 DOI: 10.1016/J.Molcel.2015.02.006  0.451
2015 Jewell JL, Kim YC, Russell RC, Yu FX, Park HW, Plouffe SW, Tagliabracci VS, Guan KL. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science (New York, N.Y.). 347: 194-8. PMID 25567907 DOI: 10.1126/Science.1259472  0.746
2014 Kim YC, Park HW, Sciarretta S, Mo JS, Jewell JL, Russell RC, Wu X, Sadoshima J, Guan KL. Rag GTPases are cardioprotective by regulating lysosomal function. Nature Communications. 5: 4241. PMID 24980141 DOI: 10.1038/Ncomms5241  0.705
2013 Yu FX, Zhang Y, Park HW, Jewell JL, Chen Q, Deng Y, Pan D, Taylor SS, Lai ZC, Guan KL. Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation. Genes & Development. 27: 1223-32. PMID 23752589 DOI: 10.1101/Gad.219402.113  0.648
2013 Jewell JL, Guan KL. Nutrient signaling to mTOR and cell growth. Trends in Biochemical Sciences. 38: 233-42. PMID 23465396 DOI: 10.1016/J.Tibs.2013.01.004  0.648
2013 Jewell JL, Russell RC, Guan KL. Amino acid signalling upstream of mTOR. Nature Reviews. Molecular Cell Biology. 14: 133-9. PMID 23361334 DOI: 10.1038/Nrm3522  0.725
2012 Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, Fu XD, Mills GB, Guan KL. Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell. 150: 780-91. PMID 22863277 DOI: 10.1016/J.Cell.2012.06.037  0.647
2011 Jewell JL, Oh E, Ramalingam L, Kalwat MA, Tagliabracci VS, Tackett L, Elmendorf JS, Thurmond DC. Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis. The Journal of Cell Biology. 193: 185-99. PMID 21444687 DOI: 10.1083/Jcb.201007176  0.687
2010 Jewell JL, Oh E, Thurmond DC. Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R517-31. PMID 20053958 DOI: 10.1152/Ajpregu.00597.2009  0.62
2008 Jewell JL, Oh E, Bennett SM, Meroueh SO, Thurmond DC. The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2beta. The Journal of Biological Chemistry. 283: 21734-46. PMID 18541526 DOI: 10.1074/Jbc.M710445200  0.646
2008 Jewell JL, Luo W, Oh E, Wang Z, Thurmond DC. Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4. The Journal of Biological Chemistry. 283: 10716-26. PMID 18285343 DOI: 10.1074/Jbc.M709876200  0.618
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