| Year |
Citation |
Score |
| 2024 |
Olivieri C, Wang Y, Walker C, Subrahmanian MV, Ha KN, Bernlohr D, Gao J, Camilloni C, Vendruscolo M, Taylor SS, Veglia G. The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A. Elife. 12. PMID 38913408 DOI: 10.7554/eLife.91506 |
0.371 |
|
| 2024 |
Trilling CR, Weng JH, Sharma PK, Nolte V, Wu J, Ma W, Boassa D, Taylor SS, Herberg FW. RedOx regulation of LRRK2 kinase activity by active site cysteines. Npj Parkinson's Disease. 10: 75. PMID 38570484 DOI: 10.1038/s41531-024-00683-5 |
0.411 |
|
| 2024 |
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, et al. Molecular determinants and signaling effects of PKA RIα phase separation. Molecular Cell. PMID 38537638 DOI: 10.1016/j.molcel.2024.03.002 |
0.393 |
|
| 2024 |
Kaila Sharma P, Weng JH, Manschwetus JT, Wu J, Ma W, Herberg FW, Taylor S. Role of the LRRK2 C-terminal tail in domain crosstalk. The Biochemical Journal. PMID 38305364 DOI: 10.1042/BCJ20230477 |
0.403 |
|
| 2023 |
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, et al. Molecular Determinants and Signaling Effects of PKA RIα Phase Separation. Biorxiv : the Preprint Server For Biology. PMID 38168176 DOI: 10.1101/2023.12.10.570836 |
0.391 |
|
| 2023 |
Kornev AP, Weng JH, Maillard RA, Taylor SS. Gauging Dynamics-driven Allostery Using a New Computational Tool: A CAP Case Study. Journal of Molecular Biology. 436: 168395. PMID 38097109 DOI: 10.1016/j.jmb.2023.168395 |
0.317 |
|
| 2023 |
Olivieri C, Wang Y, Walker C, Subrahmanian MV, Ha KN, Bernlohr DA, Gao J, Camilloni C, Vendruscolo M, Taylor SS, Veglia G. The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A. Biorxiv : the Preprint Server For Biology. PMID 37745542 DOI: 10.1101/2023.09.12.557419 |
0.402 |
|
| 2023 |
Wu J, Jonniya NA, Hirakis SP, Olivieri C, Veglia G, Kornev AP, Taylor SS. Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop. Biorxiv : the Preprint Server For Biology. PMID 37693538 DOI: 10.1101/2023.08.31.555822 |
0.396 |
|
| 2023 |
Störmer E, Weng JH, Wu J, Bertinetti D, Kaila Sharma P, Ma W, Herberg FW, Taylor S. Capturing the domain crosstalk in full length LRRK2 and LRRK2RCKW. The Biochemical Journal. PMID 37212165 DOI: 10.1042/BCJ20230126 |
0.39 |
|
| 2023 |
Lev-Ram V, Lemieux SP, Deerinck TJ, Bushong EA, Toyama BH, Perez A, Pritchard DR, Park SKR, McClatchy DB, Savas JN, Taylor SS, Ellisman MH, Yates J, Tsien RY. Do perineuronal nets stabilize the engram of a synaptic circuit? Biorxiv : the Preprint Server For Biology. PMID 37066274 DOI: 10.1101/2023.04.09.536164 |
0.333 |
|
| 2023 |
Weng JH, Ma W, Wu J, Sharma PK, Silletti S, McCammon JA, Taylor S. Capturing Differences in the Regulation of LRRK2 Dynamics and Conformational States by Small Molecule Kinase Inhibitors. Acs Chemical Biology. PMID 37043829 DOI: 10.1021/acschembio.2c00868 |
0.43 |
|
| 2023 |
Olivieri C, Walker C, Veliparambil Subrahmanian M, Porcelli F, Taylor SS, Bernlohr DA, Veglia G. An NMR portrait of functional and dysfunctional allosteric cooperativity in cAMP-dependent protein kinase A. Febs Letters. PMID 36892429 DOI: 10.1002/1873-3468.14610 |
0.475 |
|
| 2023 |
Taylor SS, Herberg FW, Veglia G, Wu J. Edmond Fischer's kinase legacy: History of the protein kinase inhibitor and protein kinase A. Iubmb Life. PMID 36855225 DOI: 10.1002/iub.2714 |
0.5 |
|
| 2023 |
Weng JH, Trilling C, Kaila Sharma P, Störmer E, Wu J, Herberg FW, Taylor SS. Novel LRR-ROC motif that links the N- and C-terminal Domains in LRRK2 undergoes an order-disorder transition upon activation. Journal of Molecular Biology. 167999. PMID 36764356 DOI: 10.1016/j.jmb.2023.167999 |
0.397 |
|
| 2022 |
Kornev AP, Aoto PC, Taylor SS. Calculation of centralities in protein kinase A. Proceedings of the National Academy of Sciences of the United States of America. 119: e2215420119. PMID 36375071 DOI: 10.1073/pnas.2215420119 |
0.33 |
|
| 2022 |
Happ JT, Arveseth CD, Bruystens J, Bertinetti D, Nelson IB, Olivieri C, Zhang J, Hedeen DS, Zhu JF, Capener JL, Bröckel JW, Vu L, King CC, Ruiz-Perez VL, Ge X, ... ... Taylor SS, et al. A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction. Nature Structural & Molecular Biology. PMID 36202993 DOI: 10.1038/s41594-022-00838-z |
0.346 |
|
| 2022 |
Pilo CA, Baffi TR, Kornev AP, Kunkel MT, Malfavon M, Chen DH, Rossitto LA, Chen DX, Huang LC, Longman C, Kannan N, Raskind WH, Gonzalez DJ, Taylor SS, Gorrie G, et al. Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition. Science Signaling. 15: eabk1147. PMID 36166510 DOI: 10.1126/scisignal.abk1147 |
0.316 |
|
| 2022 |
Olivieri C, Li GC, Wang Y, V S M, Walker C, Kim J, Camilloni C, De Simone A, Vendruscolo M, Bernlohr DA, Taylor SS, Veglia G. ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy. Science Advances. 8: eabo0696. PMID 35905186 DOI: 10.1126/sciadv.abo0696 |
0.404 |
|
| 2022 |
Weng JH, Aoto PC, Lorenz R, Wu J, Schmidt SH, Manschwetus JT, Kaila-Sharma P, Silletti S, Mathea S, Chatterjee D, Knapp S, Herberg FW, Taylor SS. LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains. Plos Biology. 20: e3001427. PMID 35192607 DOI: 10.1371/journal.pbio.3001427 |
0.398 |
|
| 2022 |
Alexa A, Sok P, Gross F, Albert K, Kobori E, Póti ÁL, Gógl G, Bento I, Kuang E, Taylor SS, Zhu F, Ciliberto A, Reményi A. A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host. Nature Communications. 13: 472. PMID 35078976 DOI: 10.1038/s41467-022-28109-x |
0.42 |
|
| 2021 |
Roa JN, Ma Y, Mikulski Z, Xu Q, Ilouz R, Taylor SS, Skowronska-Krawczyk D. Protein Kinase A in Human Retina: Differential Localization of Cβ, Cα, RIIα, and RIIβ in Photoreceptors Highlights Non-redundancy of Protein Kinase A Subunits. Frontiers in Molecular Neuroscience. 14: 782041. PMID 34867193 DOI: 10.3389/fnmol.2021.782041 |
0.31 |
|
| 2021 |
Lorenz R, Wu J, Herberg FW, Taylor SS, Engh RA. Drugging the Undruggable: How Isoquinolines and PKA Initiated the Era of Designed Protein Kinase Inhibitor Therapeutics. Biochemistry. PMID 34370450 DOI: 10.1021/acs.biochem.1c00359 |
0.439 |
|
| 2021 |
Taylor SS, Søberg K, Kobori E, Wu J, Pautz S, Herberg FW, Skålhegg BS. The tails of PKA. Molecular Pharmacology. PMID 34330820 DOI: 10.1124/molpharm.121.000315 |
0.391 |
|
| 2021 |
Walker C, Wang Y, Olivieri C, V S M, Gao J, Bernlohr DA, Calebiro D, Taylor SS, Veglia G. Is disrupted nucleotide-substrate cooperativity a common trait for Cushing's syndrome driving mutations of protein kinase A? Journal of Molecular Biology. 167123. PMID 34224748 DOI: 10.1016/j.jmb.2021.167123 |
0.349 |
|
| 2021 |
Taylor SS, Wallbott M, Machal EMF, Søberg K, Ahmed F, Bruystens J, Vu L, Baker B, Wu J, Raimondi F, Ongeri EM, Herberg FW, Skålhegg BS. PKA Cβ: a forgotten catalytic subunit of cAMP-dependent protein kinase opens new windows for PKA signaling and disease pathologies. The Biochemical Journal. 478: 2101-2119. PMID 34115095 DOI: 10.1042/BCJ20200867 |
0.385 |
|
| 2021 |
Schmidt SH, Weng JH, Aoto PC, Boassa D, Mathea S, Silletti S, Hu J, Wallbott M, Komives EA, Knapp S, Herberg FW, Taylor SS. Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34088839 DOI: 10.1073/pnas.2100844118 |
0.396 |
|
| 2021 |
Jafari N, Del Rio J, Akimoto M, Byun JA, Boulton S, Moleschi K, Alsayyed Y, Swanson P, Huang J, Martinez Pomier K, Lee C, Wu J, Taylor SS, Melacini G. Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34006641 DOI: 10.1073/pnas.2024716118 |
0.357 |
|
| 2021 |
Taylor SS, Wu J, Bruystens JGH, Del Rio JC, Lu TW, Kornev AP, Ten Eyck LF. From structure to the dynamic regulation of a molecular switch: A journey over three decades. The Journal of Biological Chemistry. 100746. PMID 33957122 DOI: 10.1016/j.jbc.2021.100746 |
0.837 |
|
| 2021 |
Baffi TR, Lordén G, Wozniak JM, Feichtner A, Yeung W, Kornev AP, King CC, Del Rio JC, Limaye AJ, Bogomolovas J, Gould CM, Chen J, Kennedy EJ, Kannan N, Gonzalez DJ, ... ... Taylor SS, et al. mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. Science Signaling. 14. PMID 33850054 DOI: 10.1126/scisignal.abe4509 |
0.406 |
|
| 2021 |
Olivieri C, Walker C, Karamafrooz A, Wang Y, Manu VS, Porcelli F, Blumenthal DK, Thomas DD, Bernlohr DA, Simon SM, Taylor SS, Veglia G. Author Correction: Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A. Communications Biology. 4: 446. PMID 33824409 DOI: 10.1038/s42003-021-02006-3 |
0.369 |
|
| 2021 |
Olivieri C, Walker C, Karamafrooz A, Wang Y, Manu VS, Porcelli F, Blumenthal DK, Thomas DD, Bernlohr DA, Sandford SM, Taylor SS, Veglia G. Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A. Communications Biology. 4: 321. PMID 33692454 DOI: 10.1038/s42003-021-01819-6 |
0.486 |
|
| 2020 |
Lu TW, Aoto PC, Weng JH, Nielsen C, Cash JN, Hall J, Zhang P, Simon SM, Cianfrocco MA, Taylor SS. Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma. Plos Biology. 18: e3001018. PMID 33370777 DOI: 10.1371/journal.pbio.3001018 |
0.851 |
|
| 2020 |
Jones AC, Taylor SS, Newton AC, Kornev AP. Hypothesis: Unifying model of domain architecture for conventional and novel protein kinase C isozymes. Iubmb Life. PMID 33166426 DOI: 10.1002/iub.2401 |
0.406 |
|
| 2020 |
Taylor SS, Kaila-Sharma P, Weng JH, Aoto P, Schmidt SH, Knapp S, Mathea S, Herberg FW. Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery. Frontiers in Molecular Neuroscience. 13: 538219. PMID 33122997 DOI: 10.3389/fnmol.2020.538219 |
0.424 |
|
| 2020 |
Zhang JZ, Lu TW, Stolerman LM, Tenner B, Yang JR, Zhang JF, Falcke M, Rangamani P, Taylor SS, Mehta S, Zhang J. Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling. Cell. PMID 32846158 DOI: 10.1016/J.Cell.2020.07.043 |
0.816 |
|
| 2020 |
Watanabe R, Buschauer R, Böhning J, Audagnotto M, Lasker K, Lu TW, Boassa D, Taylor S, Villa E. The In Situ Structure of Parkinson's Disease-Linked LRRK2. Cell. PMID 32783917 DOI: 10.1016/J.Cell.2020.08.004 |
0.819 |
|
| 2020 |
Byun JA, Akimoto M, VanSchouwen B, Lazarou TS, Taylor SS, Melacini G. Allosteric pluripotency as revealed by protein kinase A. Science Advances. 6: eabb1250. PMID 32596469 DOI: 10.1126/Sciadv.Abb1250 |
0.515 |
|
| 2020 |
Olivieri C, Wang Y, Li GC, Subrahmanian MV, Kim J, Stultz BR, Neibergall M, Porcelli F, Muretta JM, T Thomas DD, Gao J, Blumenthal DK, Taylor SS, Veglia G. Multi-state recognition pathway of the intrinsically disordered protein kinase inhibitor by protein kinase A. Elife. 9. PMID 32338601 DOI: 10.7554/Elife.55607 |
0.563 |
|
| 2020 |
Gerlits O, Weiss KL, Blakeley MP, Veglia G, Taylor SS, Kovalevsky A. Protein kinase A in the neutron beam: Insights for catalysis from directly observing protons. Methods in Enzymology. 634: 311-331. PMID 32093838 DOI: 10.1016/Bs.Mie.2019.12.003 |
0.534 |
|
| 2020 |
Olivieri C, Wang Y, Li GC, S MV, Kim J, Stultz BR, Neibergall M, Porcelli F, Muretta JM, Thomas DD, Gao J, Blumenthal DK, Taylor SS, Veglia G. Author response: Multi-state recognition pathway of the intrinsically disordered protein kinase inhibitor by protein kinase A Elife. DOI: 10.7554/Elife.55607.Sa2 |
0.456 |
|
| 2020 |
Taylor SS, Kaila-Sharma P, Weng J, Aoto P, Schmidt SH, Knapp S, Mathea S, Herberg FW. Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery Frontiers in Molecular Neuroscience. 13. DOI: 10.3389/fnmol.2020.538219 |
0.338 |
|
| 2020 |
Aoto P, Baker B, Taylor S. Protein Kinase A isoform dynamics and disease. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06840 |
0.447 |
|
| 2020 |
Lu T, Wu J, Aoto P, Weng J, Ahuja LG, Sun N, Taylor S. PKA RIα Holoenzyme Structure Reveals ATP‐Dependent Dynamics and Allosteric Regulation in Isoform‐Specific Manner The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06626 |
0.738 |
|
| 2020 |
Weng J, Auto P, Lu T, Taylor S. The structure of LRRK2 and the conformational changes that are associated with LRRK2 activation and Parkinson’s disease pathogenesis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06015 |
0.708 |
|
| 2020 |
Del-rio J, Wu L, Lu T, Aoto P, Taylor SS. Functional and Structural Characterization of Acrodysostosis Mutations of PKA RIα Reveals Mechanism Causing resistant to cAMP activation The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05949 |
0.72 |
|
| 2020 |
Pilo CA, Kunkel MT, Van AN, Kobori EK, Kornev AP, Longman C, Gorrie G, Taylor SS, Newton AC. Impaired Autoinhibition of Protein Kinase Cγ in Spinocerebellar Ataxia Type 14 Biophysical Journal. 118: 535a. DOI: 10.1096/Fasebj.2020.34.S1.04177 |
0.462 |
|
| 2020 |
Pilo CA, Kunkel MT, Van AN, Kobori EK, Longman C, Gorrie G, Taylor SS, Newton AC. Impaired Autoinhibition of Protein Kinase Cγ in Spinocerebellar Ataxia Type 14 The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.04177 |
0.355 |
|
| 2020 |
Zhang JZ, Lu T, Tenner B, Yang J, Zhang J, Taylor S, Mehta S, Zhang J. PKA RIα phase separation drives cAMP compartmentation and suppresses tumorigenic signaling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03204 |
0.699 |
|
| 2020 |
Aoto PC, Taylor SS. Dynamic Disease Landscape of a Cancer Driving Fusion Kinase Biophysical Journal. 118: 522a. DOI: 10.1016/J.Bpj.2019.11.2869 |
0.346 |
|
| 2020 |
Vu L, Taylor SS, Aoto PC, Weng J. Structural and Dynamic Effects of Phosphorylation of Protein Kinase a Catalytic Subunit Biophysical Journal. 118: 354a. DOI: 10.1016/J.Bpj.2019.11.2041 |
0.534 |
|
| 2020 |
Lu T, Taylor SS. Two PKA RIA Holoenzyme Structural States Define ATP as an Isoform Specific Orthosteric Inhibitor that Competes with Allosteric Activator, ATP Biophysical Journal. 118: 354a. DOI: 10.1016/J.Bpj.2019.11.2039 |
0.753 |
|
| 2020 |
Kobori E, Alexa A, Remenyi A, Taylor SS. Conformations of P90 Ribosomal S6 Kinase Activation Biophysical Journal. 118: 336a. DOI: 10.1016/J.Bpj.2019.11.1873 |
0.399 |
|
| 2019 |
Haushalter KJ, Schilling JM, Song Y, Sastri M, Perkins GA, Strack S, Taylor SS, Patel HH. Cardiac ischemia/reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31674811 DOI: 10.1152/Ajpheart.00237.2019 |
0.382 |
|
| 2019 |
Walker C, Wang Y, Olivieri C, Karamafrooz A, Casby J, Bathon K, Calebiro D, Gao J, Bernlohr DA, Taylor SS, Veglia G. Cushing's syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity. Science Advances. 5: eaaw9298. PMID 31489371 DOI: 10.1126/Sciadv.Aaw9298 |
0.499 |
|
| 2019 |
Hao Y, England JP, Bellucci L, Paci E, Hodges HC, Taylor SS, Maillard RA. Activation of PKA via asymmetric allosteric coupling of structurally conserved cyclic nucleotide binding domains. Nature Communications. 10: 3984. PMID 31484930 DOI: 10.1038/S41467-019-11930-2 |
0.487 |
|
| 2019 |
Röck R, Mayrhofer JE, Torres-Quesada O, Enzler F, Raffeiner A, Raffeiner P, Feichtner A, Huber RG, Koide S, Taylor SS, Troppmair J, Stefan E. BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS. Science Advances. 5: eaav8463. PMID 31453322 DOI: 10.1126/Sciadv.Aav8463 |
0.381 |
|
| 2019 |
Lu TW, Wu J, Aoto PC, Weng JH, Ahuja LG, Sun N, Cheng CY, Zhang P, Taylor SS. Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP. Proceedings of the National Academy of Sciences of the United States of America. PMID 31363049 DOI: 10.1073/Pnas.1906036116 |
0.842 |
|
| 2019 |
Schmidt SH, Knape MJ, Boassa D, Mumdey N, Kornev AP, Ellisman MH, Taylor SS, Herberg FW. The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31292254 DOI: 10.1073/Pnas.1900289116 |
0.639 |
|
| 2019 |
Ahuja LG, Aoto PC, Kornev AP, Veglia G, Taylor SS. Dynamic allostery-based molecular workings of kinase:peptide complexes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31285328 DOI: 10.1073/Pnas.1900163116 |
0.493 |
|
| 2019 |
Jewell JL, Fu V, Hong AW, Yu FX, Meng D, Melick CH, Wang H, Lam WM, Yuan HX, Taylor SS, Guan KL. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. Elife. 8. PMID 31112131 DOI: 10.7554/Elife.43038 |
0.434 |
|
| 2019 |
Ahuja LG, Taylor SS, Kornev AP. Tuning the "violin" of protein kinases: The role of dynamics-based allostery. Iubmb Life. PMID 31063633 DOI: 10.1002/Iub.2057 |
0.488 |
|
| 2019 |
Taylor SS, Meharena HS, Kornev AP. Evolution of a Dynamic Molecular Switch. Iubmb Life. PMID 31059206 DOI: 10.1002/Iub.2059 |
0.541 |
|
| 2019 |
Gerlits O, Weiss KL, Blakeley MP, Veglia G, Taylor SS, Kovalevsky A. Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex. Science Advances. 5: eaav0482. PMID 30906862 DOI: 10.1126/Sciadv.Aav0482 |
0.53 |
|
| 2019 |
Cao B, Lu TW, Martinez Fiesco JA, Tomasini M, Fan L, Simon SM, Taylor SS, Zhang P. Structures of the PKA RIα Holoenzyme with the FLHCC Driver J-PKAcα or Wild-Type PKAcα. Structure (London, England : 1993). PMID 30905674 DOI: 10.1016/J.Str.2019.03.001 |
0.846 |
|
| 2019 |
Wang Y, V S M, Kim J, Li G, Ahuja LG, Aoto P, Taylor SS, Veglia G. Globally correlated conformational entropy underlies positive and negative cooperativity in a kinase's enzymatic cycle. Nature Communications. 10: 799. PMID 30778078 DOI: 10.1038/S41467-019-08655-7 |
0.483 |
|
| 2019 |
Zhang P, Fan Y, Ru H, Wang L, Magupalli VG, Taylor SS, Alessi DR, Wu H. Crystal structure of the WD40 domain dimer of LRRK2. Proceedings of the National Academy of Sciences of the United States of America. PMID 30635421 DOI: 10.2210/Pdb6Dlo/Pdb |
0.497 |
|
| 2019 |
Gógl G, Kornev AP, Reményi A, Taylor SS. Disordered Protein Kinase Regions in Regulation of Kinase Domain Cores. Trends in Biochemical Sciences. PMID 30611608 DOI: 10.1016/J.Tibs.2018.12.002 |
0.515 |
|
| 2019 |
Jewell JL, Fu V, Hong AW, Yu F, Meng D, Melick CH, Wang H, Lam WM, Yuan H, Taylor SS, Guan K. Author response: GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor Elife. DOI: 10.7554/Elife.43038.019 |
0.365 |
|
| 2018 |
Adame-García SR, Cervantes-Villagrana RD, Orduña-Castillo LB, Del Rio JC, Gutkind JS, Reyes-Cruz G, Taylor SS, Vázquez-Prado J. cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunits. The Journal of Biological Chemistry. PMID 30530493 DOI: 10.1074/Jbc.Ra118.006691 |
0.424 |
|
| 2018 |
Meng Y, Ahuja LG, Kornev AP, Taylor SS, Roux B. Corrigendum to "A Catalytically-Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation." J. Mol. Biol. 430(6) (Mar 16 2018), 881-889. Journal of Molecular Biology. PMID 30220583 DOI: 10.1016/J.Jmb.2018.09.001 |
0.442 |
|
| 2018 |
Raju S, Whalen DM, Mengistu M, Swanson C, Quinn JG, Taylor SS, Webster JD, Newton K, Shaw AS. Kinase domain dimerization drives RIPK3-dependent necroptosis. Science Signaling. 11. PMID 30131368 DOI: 10.1126/Scisignal.Aar2188 |
0.498 |
|
| 2018 |
Flippo KH, Gnanasekaran A, Perkins GA, Ahmad A, Merrill RA, Dickey AS, Taylor SS, McKnight GS, Chauhan AK, Usachev YM, Strack S. AKAP1 protects from cerebral ischemic stroke by inhibiting Drp1-dependent mitochondrial fission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30093535 DOI: 10.1523/Jneurosci.0649-18.2018 |
0.322 |
|
| 2018 |
England JP, Hao Y, Bai L, Glick V, Hodges HC, Taylor SS, Maillard RA. Switching of the folding-energy landscape governs the allosteric activation of protein kinase A. Proceedings of the National Academy of Sciences of the United States of America. PMID 30038016 DOI: 10.1073/Pnas.1802510115 |
0.533 |
|
| 2018 |
Meng Y, Ahuja LG, Kornev AP, Taylor SS, Roux B. A Catalytically-Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation. Journal of Molecular Biology. PMID 29410316 DOI: 10.1016/J.Jmb.2018.01.019 |
0.507 |
|
| 2018 |
Haushalter KJ, Casteel DE, Raffeiner A, Stefan E, Patel HH, Taylor SS. Phosphorylation of Protein Kinase A (PKA) regulatory subunit RIα by Protein Kinase G (PKG) primes PKA for catalytic activity in cells. The Journal of Biological Chemistry. PMID 29378851 DOI: 10.1074/Jbc.M117.809988 |
0.554 |
|
| 2018 |
Tomasini MD, Wang Y, Karamafrooz A, Li G, Beuming T, Gao J, Taylor SS, Veglia G, Simon SM. Conformational Landscape of the PRKACA-DNAJB1 Chimeric Kinase, the Driver for Fibrolamellar Hepatocellular Carcinoma. Scientific Reports. 8: 720. PMID 29335433 DOI: 10.1038/S41598-017-18956-W |
0.522 |
|
| 2018 |
Tomasini MD, Wang Y, Karamafrooz A, Hall J, Taylor SS, Beuming T, Veglia G, Simon SM. Abstract 4142: Conformational dynamics of the chimeric kinase DNAJB1-PRKACA, the driver for fibrolamellar hepatocellular carcinoma Cancer Research. 78: 4142-4142. DOI: 10.1158/1538-7445.Am2018-4142 |
0.496 |
|
| 2018 |
Ahuja LG, Meng Y, Kornev AP, Roux B, Taylor S. An Allosteric Region of Src Tyrosine Kinase Allows for Stabilization of Its Active-Like Conformation Biophysical Journal. 114: 398a. DOI: 10.1016/J.Bpj.2017.11.2201 |
0.438 |
|
| 2017 |
Bubis J, Martínez JC, Calabokis M, Ferreira J, Sanz-Rodríguez CE, Navas V, Escalona JL, Guo Y, Taylor SS. The gene product of a Trypanosoma equiperdum ortholog of the cAMP-dependent protein kinase regulatory subunit is a monomeric protein that is not capable of binding cyclic nucleotides. Biochimie. PMID 29288679 DOI: 10.1016/J.Biochi.2017.12.010 |
0.693 |
|
| 2017 |
Hao Y, Canavan C, Taylor SS, Maillard RA. Integrated Method to Attach DNA Handles and Functionally Select Proteins to Study Folding and Protein-Ligand Interactions with Optical Tweezers. Scientific Reports. 7: 10843. PMID 28883488 DOI: 10.1038/S41598-017-11214-Z |
0.404 |
|
| 2017 |
Sastri M, Darshi M, Mackey M, Ramachandra R, Ju S, Phan S, Adams S, Stein K, Douglas CR, Kim JJ, Ellisman MH, Taylor SS, Perkins GA. Sub-mitochondrial localization of genetic-tagged MIB interacting partners: Mic19, Mic60 and Sam50. Journal of Cell Science. PMID 28808085 DOI: 10.1242/Jcs.201400 |
0.458 |
|
| 2017 |
Kim J, Ahuja LG, Chao FA, Xia Y, McClendon CL, Kornev AP, Taylor SS, Veglia G. A dynamic hydrophobic core orchestrates allostery in protein kinases. Science Advances. 3: e1600663. PMID 28435869 DOI: 10.1126/Sciadv.1600663 |
0.541 |
|
| 2017 |
Pecora de Barros E, Malmstrom RD, Nourbakhsh K, Del Rio JC, Kornev AP, Taylor SS, Amaro RE. Electrostatic interactions as mediators in the allosteric activation of PKA RIα. Biochemistry. PMID 28221775 DOI: 10.1021/Acs.Biochem.6B01152 |
0.487 |
|
| 2017 |
Ahuja LG, Kornev AP, McClendon CL, Veglia G, Taylor SS. Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115705 DOI: 10.1073/Pnas.1620667114 |
0.537 |
|
| 2017 |
Ilouz R, Lev-Ram V, Bushong EA, Stiles TL, Friedmann-Morvinski D, Douglas C, Goldberg G, Ellisman MH, Taylor SS. Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain. Elife. 6. PMID 28079521 DOI: 10.7554/Elife.17681 |
0.522 |
|
| 2017 |
Taylor SS, Kornev AP. PKA and the Structural Kinome Periodicum Biologorum. 118. DOI: 10.18054/Pb.V118I4.4846 |
0.382 |
|
| 2017 |
Lu T, Cianfrocco M, Zhang P, Taylor S. Fusion Protein, DNAJB1-PRKACA, as a Cancer Driver Biophysical Journal. 112: 489a. DOI: 10.1016/J.Bpj.2016.11.2646 |
0.7 |
|
| 2017 |
Kornev AP, Taylor SS. Fractal Nature of Protein Interior and its Implications for Protein Function Biophysical Journal. 112: 194a-195a. DOI: 10.1016/J.Bpj.2016.11.1079 |
0.358 |
|
| 2017 |
Taylor SS. PKA: Dynamic Assembly and Regulation of Macromolecular Signaling Complexes Biophysical Journal. 112: 11a. DOI: 10.1016/J.Bpj.2016.11.092 |
0.547 |
|
| 2016 |
Meharena HS, Fan X, Ahuja LG, Keshwani MM, McClendon CL, Chen AM, Adams JA, Taylor SS. Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases. Plos Biology. 14: e2000127. PMID 27902690 DOI: 10.1371/Journal.Pbio.2000127 |
0.502 |
|
| 2016 |
Bruystens JG, Wu J, Fortezzo A, Del Rio J, Nielsen C, Blumenthal DK, Rock R, Stefan E, Taylor SS. Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation. Journal of Molecular Biology. PMID 27825928 DOI: 10.1016/J.Jmb.2016.10.033 |
0.509 |
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| 2016 |
Bachmann VA, Mayrhofer JE, Ilouz R, Tschaikner P, Raffeiner P, Röck R, Courcelles M, Apelt F, Lu TW, Baillie GS, Thibault P, Aanstad P, Stelzl U, Taylor SS, Stefan E. Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 27357676 DOI: 10.1073/Pnas.1608061113 |
0.845 |
|
| 2016 |
Burgers PP, Bruystens J, Burnley RJ, Nikolaev VO, Keshwani M, Wu J, Janssen BJ, Taylor SS, Heck AJ, Scholten A. Structure of smAKAP and its regulation by PKA-mediated phosphorylation. The Febs Journal. PMID 27028580 DOI: 10.1111/Febs.13726 |
0.578 |
|
| 2016 |
Kim J, Li G, Walters MA, Taylor SS, Veglia G. Uncoupling Catalytic and Binding Functions in the Cyclic AMP-Dependent Protein Kinase A. Structure (London, England : 1993). PMID 26833386 DOI: 10.1016/J.Str.2015.11.016 |
0.531 |
|
| 2016 |
Chávez-Vargas L, Adame-García SR, Cervantes-Villagrana RD, Castillo-Kauil A, Bruystens JG, Fukuhara S, Taylor SS, Mochizuki N, Reyes-Cruz G, Vázquez-Prado J. Protein kinase A (PKA) Type I interacts with P-Rex1, a Rac guanine nucleotide exchange factor: Effect on PKA localization and P-Rex1 signaling. The Journal of Biological Chemistry. PMID 26797121 DOI: 10.1074/Jbc.M115.712216 |
0.434 |
|
| 2016 |
Malmstrom RD, Kornev AP, Taylor SS, Amaro RE. Protein-Ligand Interactions through the Computational Microscope: Allostery in a Canonical Signaling Domain Biophysical Journal. 110: 52a. DOI: 10.1016/J.Bpj.2015.11.346 |
0.453 |
|
| 2016 |
Wang Y, Cembran A, Gao J, Veglia G, Taylor SS, Simon SM. Molecular Dynamics Simulation and Markov State Model Reveal Irregular Metastable Conformation and Allostery In DNAJB-PKAc Biophysical Journal. 110: 51a-52a. DOI: 10.1016/J.Bpj.2015.11.343 |
0.446 |
|
| 2016 |
Karamafrooz AN, Kim J, Li G, Simon SM, Taylor SS, Veglia G. NMR Structural/Functional Characterization of an Oncogenic Mutant of cAMP-Dependent Protein Kinase A: PRKACA-DNAJB1 Biophysical Journal. 110: 47a. DOI: 10.1016/J.Bpj.2015.11.319 |
0.534 |
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| 2016 |
Li G, Olivieri C, Neibergall M, Kim J, Taylor S, Muretta J, Veglia G. Elucidating the Mechanism of Recognition and Binding of Protein Kinase Inhibitor by Protein Kinase a using NMR and Fluorescence Spectroscopy Biophysical Journal. 110: 558a. DOI: 10.1016/J.Bpj.2015.11.2984 |
0.584 |
|
| 2015 |
Akimoto M, McNicholl ET, Ramkissoon A, Moleschi K, Taylor SS, Melacini G. Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα. Plos Biology. 13: e1002305. PMID 26618408 DOI: 10.1371/Journal.Pbio.1002305 |
0.556 |
|
| 2015 |
Kornev AP, Taylor SS. Dynamics-Driven Allostery in Protein Kinases. Trends in Biochemical Sciences. 40: 628-47. PMID 26481499 DOI: 10.1016/J.Tibs.2015.09.002 |
0.471 |
|
| 2015 |
Keshwani MM, Kanter JR, Ma Y, Wilderman A, Darshi M, Insel PA, Taylor SS. Mechanisms of cyclic AMP/protein kinase A- and glucocorticoid-mediated apoptosis using S49 lymphoma cells as a model system. Proceedings of the National Academy of Sciences of the United States of America. PMID 26417071 DOI: 10.1073/Pnas.1516057112 |
0.354 |
|
| 2015 |
Antal CE, Callender JA, Kornev AP, Taylor SS, Newton AC. Intramolecular C2 Domain-Mediated Autoinhibition of Protein Kinase C βII. Cell Reports. 12: 1252-60. PMID 26279568 DOI: 10.1016/J.Celrep.2015.07.039 |
0.5 |
|
| 2015 |
Zhang P, Ye F, Bastidas AC, Kornev AP, Wu J, Ginsberg MH, Taylor SS. An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes. Structure (London, England : 1993). PMID 26278174 DOI: 10.1016/J.Str.2015.07.007 |
0.811 |
|
| 2015 |
Wilderman A, Guo Y, Divakaruni AS, Perkins G, Zhang L, Murphy AN, Taylor SS, Insel PA. Proteomic and Metabolic Analyses of S49 Lymphoma Cells Reveal Novel Regulation of Mitochondria by cAMP and Protein Kinase A. The Journal of Biological Chemistry. 290: 22274-86. PMID 26203188 DOI: 10.1074/Jbc.M115.658153 |
0.398 |
|
| 2015 |
Knape MJ, Ahuja LG, Bertinetti D, Burghardt NC, Zimmermann B, Taylor SS, Herberg FW. Divalent Metal Ions Mg(2+) and Ca(2+) Have Distinct Effects on Protein Kinase A Activity and Regulation. Acs Chemical Biology. 10: 2303-15. PMID 26200257 DOI: 10.1021/Acschembio.5B00271 |
0.393 |
|
| 2015 |
Zhang P, Knape MJ, Ahuja LG, Keshwani MM, King CC, Sastri M, Herberg FW, Taylor SS. Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme. Plos Biology. 13: e1002192. PMID 26158466 DOI: 10.1371/Journal.Pbio.1002192 |
0.499 |
|
| 2015 |
Malmstrom RD, Kornev AP, Taylor SS, Amaro RE. Allostery through the computational microscope: cAMP activation of a canonical signalling domain. Nature Communications. 6: 7588. PMID 26145448 DOI: 10.1038/Ncomms8588 |
0.479 |
|
| 2015 |
Zhang P, Kornev AP, Wu J, Taylor SS. Discovery of Allostery in PKA Signaling. Biophysical Reviews. 7: 227-238. PMID 26097522 DOI: 10.1007/S12551-015-0170-X |
0.559 |
|
| 2015 |
Li GC, Srivastava AK, Kim J, Taylor SS, Veglia G. Mapping the Hydrogen Bond Networks in the Catalytic Subunit of Protein Kinase A Using H/D Fractionation Factors. Biochemistry. 54: 4042-9. PMID 26030372 DOI: 10.1021/Acs.Biochem.5B00387 |
0.451 |
|
| 2015 |
Iglesias-Bartolome R, Torres D, Marone R, Feng X, Martin D, Simaan M, Chen M, Weinstein LS, Taylor SS, Molinolo AA, Gutkind JS. Inactivation of a Gαs-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nature Cell Biology. 17: 793-803. PMID 25961504 DOI: 10.1038/Ncb3164 |
0.326 |
|
| 2015 |
Taylor SS, Shaw AS, Kannan N, Kornev AP. Integration of signaling in the kinome: Architecture and regulation of the αC Helix. Biochimica Et Biophysica Acta. PMID 25891902 DOI: 10.1016/J.Bbapap.2015.04.007 |
0.526 |
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| 2015 |
Mohanty S, Kennedy EJ, Herberg FW, Hui R, Taylor SS, Langsley G, Kannan N. Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design. Biochimica Et Biophysica Acta. PMID 25847873 DOI: 10.1016/J.Bbapap.2015.03.012 |
0.44 |
|
| 2015 |
Kim J, Masterson LR, Cembran A, Verardi R, Shi L, Gao J, Taylor SS, Veglia G. Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 112: 3716-21. PMID 25775607 DOI: 10.1073/Pnas.1502299112 |
0.549 |
|
| 2015 |
McSkimming DI, Dastgheib S, Talevich E, Narayanan A, Katiyar S, Taylor SS, Kochut K, Kannan N. ProKinO: a unified resource for mining the cancer kinome. Human Mutation. 36: 175-86. PMID 25382819 DOI: 10.1002/Humu.22726 |
0.429 |
|
| 2015 |
Niyitegeka JM, Bastidas AC, Newman RH, Taylor SS, Ongeri EM. Isoform-specific interactions between meprin metalloproteases and the catalytic subunit of protein kinase A: significance in acute and chronic kidney injury. American Journal of Physiology. Renal Physiology. 308: F56-68. PMID 25354939 DOI: 10.1152/Ajprenal.00167.2014 |
0.814 |
|
| 2015 |
Hu J, Ahuja LG, Meharena HS, Kannan N, Kornev AP, Taylor SS, Shaw AS. Kinase regulation by hydrophobic spine assembly in cancer. Molecular and Cellular Biology. 35: 264-76. PMID 25348715 DOI: 10.1128/Mcb.00943-14 |
0.418 |
|
| 2015 |
Sarma GN, Moody IS, Ilouz R, Phan RH, Sankaran B, Hall RA, Taylor SS. D-AKAP2:PKA RII:PDZK1 ternary complex structure: insights from the nucleation of a polyvalent scaffold. Protein Science : a Publication of the Protein Society. 24: 105-16. PMID 25348485 DOI: 10.1002/Pro.2593 |
0.484 |
|
| 2015 |
Bastidas AC, Wu J, Taylor SS. Molecular features of product release for the PKA catalytic cycle. Biochemistry. 54: 2-10. PMID 25077557 DOI: 10.1021/Bi500684C |
0.818 |
|
| 2015 |
Zhang P, Knape MJ, Ahuja LG, Keshwani MM, King CC, Sastri M, Herberg FW, Taylor SS. Endogenous RIIβ is constitutionally phosphorylated in 3T3 and HeLa cells. Plos Biology. DOI: 10.1371/Journal.Pbio.1002192.G007 |
0.317 |
|
| 2015 |
Zhang P, Knape MJ, Ahuja LG, Keshwani MM, King CC, Sastri M, Herberg FW, Taylor SS. Single turnover and pre-steady-state kinetics for RIIβ holoenzyme phosphorylation in the presence of Mg 2+ versus Ca 2+ . Plos Biology. DOI: 10.1371/Journal.Pbio.1002192.G003 |
0.301 |
|
| 2015 |
Zhang P, Knape MJ, Ahuja LG, Keshwani MM, King CC, Sastri M, Herberg FW, Taylor SS. Crystal structures of the RIIβ holoenzyme showing active site phosphorylation in the presence of calcium. Plos Biology. DOI: 10.1371/Journal.Pbio.1002192.G001 |
0.375 |
|
| 2014 |
Srivastava AK, McDonald LR, Cembran A, Kim J, Masterson LR, McClendon CL, Taylor SS, Veglia G. Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling. Structure (London, England : 1993). 22: 1735-43. PMID 25458836 DOI: 10.1016/J.Str.2014.09.010 |
0.504 |
|
| 2014 |
McClendon CL, Kornev AP, Gilson MK, Taylor SS. Dynamic architecture of a protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 111: E4623-31. PMID 25319261 DOI: 10.1073/Pnas.1418402111 |
0.491 |
|
| 2014 |
Boras BW, Kornev A, Taylor SS, McCulloch AD. Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIα activation in response to cAMP binding. The Journal of Biological Chemistry. 289: 30040-51. PMID 25202018 DOI: 10.1074/Jbc.M114.568907 |
0.489 |
|
| 2014 |
Blumenthal DK, Copps J, Smith-Nguyen EV, Zhang P, Heller WT, Taylor SS. The roles of the RIIβ linker and N-terminal cyclic nucleotide-binding domain in determining the unique structures of the type IIβ protein kinase A: a small angle x-ray and neutron scattering study. The Journal of Biological Chemistry. 289: 28505-12. PMID 25112875 DOI: 10.1074/Jbc.M114.584177 |
0.541 |
|
| 2014 |
Gerlits O, Das A, Keshwani MM, Taylor S, Waltman MJ, Langan P, Heller WT, Kovalevsky A. Metal-free cAMP-dependent protein kinase can catalyze phosphoryl transfer. Biochemistry. 53: 3179-86. PMID 24786636 DOI: 10.1021/Bi5000965 |
0.425 |
|
| 2014 |
Shaw AS, Kornev AP, Hu J, Ahuja LG, Taylor SS. Kinases and pseudokinases: lessons from RAF. Molecular and Cellular Biology. 34: 1538-46. PMID 24567368 DOI: 10.1128/Mcb.00057-14 |
0.509 |
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| 2014 |
Akimoto M, Moleschi K, Boulton S, VanSchouwen B, Selvaratnam R, Taylor SS, Melacini G. Allosteric linkers in cAMP signalling. Biochemical Society Transactions. 42: 139-44. PMID 24450641 DOI: 10.1042/Bst20130257 |
0.496 |
|
| 2014 |
Bruystens JG, Wu J, Fortezzo A, Kornev AP, Blumenthal DK, Taylor SS. PKA RIα homodimer structure reveals an intermolecular interface with implications for cooperative cAMP binding and Carney complex disease. Structure (London, England : 1993). 22: 59-69. PMID 24316401 DOI: 10.1016/J.Str.2013.10.012 |
0.491 |
|
| 2014 |
Gerlits O, Das A, Tian J, Keshwani M, Taylor S, Waltman MJ, Langan P, Heller W, Kovalevsky A. Insights into the phosphoryl transfer catalyzed by cAMP-dependent protein kinase Acta Crystallographica Section a Foundations and Advances. 70: C449-C449. DOI: 10.1107/S2053273314095503 |
0.509 |
|
| 2014 |
Wilderman A, Guo Y, Taylor S, Insel P. cAMP/PKA-mediated regulation of amino acid metabolism in murine T-lymphoma cells (1095.16) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1095.16 |
0.379 |
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| 2014 |
Boras B, Taylor S, McCulloch A. Direct PKA-PDE interactions lead to localized cAMP signaling domains in adult cardiomyocytes (1013.7) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1013.7 |
0.403 |
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| 2014 |
Zhang P, Copps J, Blumenthal D, Taylor S. Assembly of Protein Kinase a RIIβ Macromolecular Complexes Biophysical Journal. 106: 464a. DOI: 10.1016/J.Bpj.2013.11.2629 |
0.506 |
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| 2013 |
Meharena HS, Chang P, Keshwani MM, Oruganty K, Nene AK, Kannan N, Taylor SS, Kornev AP. Deciphering the structural basis of eukaryotic protein kinase regulation. Plos Biology. 11: e1001680. PMID 24143133 DOI: 10.1371/Journal.Pbio.1001680 |
0.546 |
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| 2013 |
Guo Y, Darshi M, Ma Y, Perkins GA, Shen Z, Haushalter KJ, Saito R, Chen A, Lee YS, Patel HH, Briggs SP, Ellisman MH, Olefsky JM, Taylor SS. Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice. Molecular & Cellular Proteomics : McP. 12: 3744-58. PMID 24030101 DOI: 10.1074/Mcp.M113.027441 |
0.48 |
|
| 2013 |
Bastidas AC, Pierce LC, Walker RC, Johnson DA, Taylor SS. Influence of N-myristylation and ligand binding on the flexibility of the catalytic subunit of protein kinase A. Biochemistry. 52: 6368-79. PMID 24003983 DOI: 10.1021/Bi400575K |
0.827 |
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| 2013 |
Hu J, Stites EC, Yu H, Germino EA, Meharena HS, Stork PJ, Kornev AP, Taylor SS, Shaw AS. Allosteric activation of functionally asymmetric RAF kinase dimers. Cell. 154: 1036-46. PMID 23993095 DOI: 10.1016/J.Cell.2013.07.046 |
0.474 |
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| 2013 |
Brown SH, Cheng CY, Saldanha SA, Wu J, Cottam HB, Sankaran B, Taylor SS. Implementing fluorescence anisotropy screening and crystallographic analysis to define PKA isoform-selective activation by cAMP analogs. Acs Chemical Biology. 8: 2164-72. PMID 23978166 DOI: 10.1021/Cb400247T |
0.682 |
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| 2013 |
Akimoto M, Selvaratnam R, McNicholl ET, Verma G, Taylor SS, Melacini G. Signaling through dynamic linkers as revealed by PKA. Proceedings of the National Academy of Sciences of the United States of America. 110: 14231-6. PMID 23946424 DOI: 10.1073/Pnas.1312644110 |
0.454 |
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| 2013 |
Taylor SS, Shaw A, Hu J, Meharena HS, Kornev A. Pseudokinases from a structural perspective. Biochemical Society Transactions. 41: 981-6. PMID 23863167 DOI: 10.1042/Bst20130120 |
0.566 |
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| 2013 |
Yu FX, Zhang Y, Park HW, Jewell JL, Chen Q, Deng Y, Pan D, Taylor SS, Lai ZC, Guan KL. Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation. Genes & Development. 27: 1223-32. PMID 23752589 DOI: 10.1101/Gad.219402.113 |
0.466 |
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| 2013 |
Gerlits O, Waltman MJ, Taylor S, Langan P, Kovalevsky A. Insights into the phosphoryl transfer catalyzed by cAMP-dependent protein kinase: An X-ray crystallographic study of complexes with various metals and peptide substrate SP20 Biochemistry. 52: 3721-3727. PMID 23672593 DOI: 10.1021/Bi400066A |
0.458 |
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| 2013 |
Taylor SS, Zhang P, Steichen JM, Keshwani MM, Kornev AP. PKA: lessons learned after twenty years. Biochimica Et Biophysica Acta. 1834: 1271-8. PMID 23535202 DOI: 10.1016/J.Bbapap.2013.03.007 |
0.808 |
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| 2013 |
Bastidas AC, Deal MS, Steichen JM, Guo Y, Wu J, Taylor SS. Phosphoryl transfer by protein kinase A is captured in a crystal lattice. Journal of the American Chemical Society. 135: 4788-98. PMID 23458248 DOI: 10.1021/Ja312237Q |
0.834 |
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| 2013 |
Sastri M, Haushalter KJ, Panneerselvam M, Chang P, Fridolfsson H, Finley JC, Ng D, Schilling JM, Miyanohara A, Day ME, Hakozaki H, Petrosyan S, Koller A, King CC, Darshi M, ... ... Taylor SS, et al. A kinase interacting protein (AKIP1) is a key regulator of cardiac stress. Proceedings of the National Academy of Sciences of the United States of America. 110: E387-96. PMID 23319652 DOI: 10.1073/Pnas.1221670110 |
0.311 |
|
| 2012 |
Cembran A, Masterson LR, McClendon CL, Taylor SS, Gao J, Veglia G. Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations. Biochemistry. 51: 10186-96. PMID 23205665 DOI: 10.1021/Bi301279F |
0.491 |
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| 2012 |
Burgers PP, Ma Y, Margarucci L, Mackey M, van der Heyden MA, Ellisman M, Scholten A, Taylor SS, Heck AJ. A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane. The Journal of Biological Chemistry. 287: 43789-97. PMID 23115245 DOI: 10.1074/Jbc.M112.395970 |
0.623 |
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| 2012 |
Guo Y, Wilderman A, Zhang L, Taylor SS, Insel PA. Quantitative proteomics analysis of the cAMP/protein kinase A signaling pathway. Biochemistry. 51: 9323-32. PMID 23110364 DOI: 10.1021/Bi301282K |
0.4 |
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| 2012 |
Xu X, Keshwani M, Meyer K, Sarikas A, Taylor S, Pan ZQ. Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination. The Journal of Biological Chemistry. 287: 40758-66. PMID 23045529 DOI: 10.1074/Jbc.M112.405209 |
0.442 |
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| 2012 |
Darshi M, Trinh KN, Murphy AN, Taylor SS. Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. The Journal of Biological Chemistry. 287: 39480-91. PMID 23019327 DOI: 10.1074/Jbc.M112.387696 |
0.454 |
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| 2012 |
Taylor SS, Ilouz R, Zhang P, Kornev AP. Assembly of allosteric macromolecular switches: lessons from PKA. Nature Reviews. Molecular Cell Biology. 13: 646-58. PMID 22992589 DOI: 10.1038/Nrm3432 |
0.558 |
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| 2012 |
Taylor SS, Keshwani MM, Steichen JM, Kornev AP. Evolution of the eukaryotic protein kinases as dynamic molecular switches. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2517-28. PMID 22889904 DOI: 10.1098/Rstb.2012.0054 |
0.792 |
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| 2012 |
Kükrer B, Barbu IM, Copps J, Hogan P, Taylor SS, van Duijn E, Heck AJ. Conformational isomers of calcineurin follow distinct dissociation pathways. Journal of the American Society For Mass Spectrometry. 23: 1534-43. PMID 22811075 DOI: 10.1007/S13361-012-0441-8 |
0.329 |
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| 2012 |
Ilouz R, Bubis J, Wu J, Yim YY, Deal MS, Kornev AP, Ma Y, Blumenthal DK, Taylor SS. Localization and quaternary structure of the PKA RIβ holoenzyme. Proceedings of the National Academy of Sciences of the United States of America. 109: 12443-8. PMID 22797896 DOI: 10.1073/Pnas.1209538109 |
0.669 |
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| 2012 |
Kovalevsky AY, Johnson H, Hanson BL, Waltman MJ, Fisher SZ, Taylor S, Langan P. Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallographica. Section D, Biological Crystallography. 68: 854-60. PMID 22751671 DOI: 10.1107/S0907444912014886 |
0.465 |
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| 2012 |
Haste NM, Talabani H, Doo A, Merckx A, Langsley G, Taylor SS. Exploring the Plasmodium falciparum cyclic-adenosine monophosphate (cAMP)-dependent protein kinase (PfPKA) as a therapeutic target. Microbes and Infection / Institut Pasteur. 14: 838-50. PMID 22626931 DOI: 10.1016/J.Micinf.2012.05.004 |
0.501 |
|
| 2012 |
Bastidas AC, Deal MS, Steichen JM, Keshwani MM, Guo Y, Taylor SS. Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. Journal of Molecular Biology. 422: 215-29. PMID 22617327 DOI: 10.1016/J.Jmb.2012.05.021 |
0.841 |
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| 2012 |
Keshwani MM, Klammt C, von Daake S, Ma Y, Kornev AP, Choe S, Insel PA, Taylor SS. Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 109: E1221-9. PMID 22493239 DOI: 10.1073/Pnas.1202741109 |
0.543 |
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| 2012 |
Steichen JM, Kuchinskas M, Keshwani MM, Yang J, Adams JA, Taylor SS. Structural basis for the regulation of protein kinase A by activation loop phosphorylation. The Journal of Biological Chemistry. 287: 14672-80. PMID 22334660 DOI: 10.1074/Jbc.M111.335091 |
0.798 |
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| 2012 |
Zhang P, Smith-Nguyen EV, Keshwani MM, Deal MS, Kornev AP, Taylor SS. Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Science (New York, N.Y.). 335: 712-6. PMID 22323819 DOI: 10.1126/Science.1213979 |
0.512 |
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| 2012 |
Abrahamsen H, O'Neill AK, Kannan N, Kruse N, Taylor SS, Jennings PA, Newton AC. Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes. The Journal of Biological Chemistry. 287: 13262-78. PMID 22318721 DOI: 10.1074/Jbc.M112.349753 |
0.521 |
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| 2012 |
Yang J, Wu J, Steichen JM, Kornev AP, Deal MS, Li S, Sankaran B, Woods VL, Taylor SS. A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold. Journal of Molecular Biology. 415: 666-79. PMID 22138346 DOI: 10.1016/J.Jmb.2011.11.035 |
0.787 |
|
| 2012 |
Ilouz R, Bubis J, Wu J, Yim Y, Kornev A, Blumenthal D, Taylor S. Crystal Structure of Full-Length PKA Rib: Insights Into Novel Isoform Specificity of Tetrameric Holoenzyme Assembly Hormone and Metabolic Research. 44. DOI: 10.1055/s-0032-1304229 |
0.535 |
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| 2011 |
Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy AN, Ha T, Santana LF, Tasken K, Scott JD. An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 108: E1227-35. PMID 22084075 DOI: 10.1073/Pnas.1107182108 |
0.557 |
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| 2011 |
Osborne BW, Wu J, McFarland CJ, Nickl CK, Sankaran B, Casteel DE, Woods VL, Kornev AP, Taylor SS, Dostmann WR. Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication. Structure (London, England : 1993). 19: 1317-27. PMID 21893290 DOI: 10.1016/J.Str.2011.06.012 |
0.51 |
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| 2011 |
Keshwani MM, von Daake S, Newton AC, Harris TK, Taylor SS. Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1). The Journal of Biological Chemistry. 286: 23552-8. PMID 21561857 DOI: 10.1074/Jbc.M111.258004 |
0.545 |
|
| 2011 |
King CC, Sastri M, Chang P, Pennypacker J, Taylor SS. The rate of NF-κB nuclear translocation is regulated by PKA and A kinase interacting protein 1. Plos One. 6: e18713. PMID 21556136 DOI: 10.1371/Journal.Pone.0018713 |
0.396 |
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| 2011 |
Day ME, Gaietta GM, Sastri M, Koller A, Mackey MR, Scott JD, Perkins GA, Ellisman MH, Taylor SS. Isoform-specific targeting of PKA to multivesicular bodies. The Journal of Cell Biology. 193: 347-63. PMID 21502359 DOI: 10.1083/Jcb.201010034 |
0.645 |
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| 2011 |
Masterson LR, Shi L, Metcalfe E, Gao J, Taylor SS, Veglia G. Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 108: 6969-74. PMID 21471451 DOI: 10.1073/Pnas.1102701108 |
0.452 |
|
| 2011 |
Hu J, Yu H, Kornev AP, Zhao J, Filbert EL, Taylor SS, Shaw AS. Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF. Proceedings of the National Academy of Sciences of the United States of America. 108: 6067-72. PMID 21441104 DOI: 10.1073/Pnas.1102554108 |
0.442 |
|
| 2011 |
Boettcher AJ, Wu J, Kim C, Yang J, Bruystens J, Cheung N, Pennypacker JK, Blumenthal DA, Kornev AP, Taylor SS. Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme. Structure (London, England : 1993). 19: 265-76. PMID 21300294 DOI: 10.1016/J.Str.2010.12.005 |
0.495 |
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| 2011 |
McLaughlin WA, Hou T, Taylor SS, Wang W. The identification of novel cyclic AMP-dependent protein kinase anchoring proteins using bioinformatic filters and peptide arrays. Protein Engineering, Design & Selection : Peds. 24: 333-9. PMID 21115539 DOI: 10.1093/Protein/Gzq106 |
0.529 |
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| 2011 |
Badireddy S, Yunfeng G, Ritchie M, Akamine P, Wu J, Kim CW, Taylor SS, Qingsong L, Swaminathan K, Anand GS. Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design. Molecular & Cellular Proteomics : McP. 10: M110.004390. PMID 21081668 DOI: 10.1074/Mcp.M110.004390 |
0.822 |
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| 2011 |
Darshi M, Mendiola VL, Mackey MR, Murphy AN, Koller A, Perkins GA, Ellisman MH, Taylor SS. ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function. The Journal of Biological Chemistry. 286: 2918-32. PMID 21081504 DOI: 10.1074/Jbc.M110.171975 |
0.524 |
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| 2011 |
Taylor SS, Kornev AP. Protein kinases: evolution of dynamic regulatory proteins. Trends in Biochemical Sciences. 36: 65-77. PMID 20971646 DOI: 10.1016/J.Tibs.2010.09.006 |
0.481 |
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| 2011 |
Masterson LR, Cheng C, Yu T, Tonelli M, Kornev A, Taylor SS, Veglia G. Erratum: Corrigendum: Dynamics connect substrate recognition to catalysis in protein kinase A Nature Chemical Biology. 7: 319-319. DOI: 10.1038/Nchembio0511-319 |
0.653 |
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| 2010 |
Rinaldi J, Wu J, Yang J, Ralston CY, Sankaran B, Moreno S, Taylor SS. Structure of yeast regulatory subunit: a glimpse into the evolution of PKA signaling. Structure (London, England : 1993). 18: 1471-82. PMID 21070946 DOI: 10.1016/J.Str.2010.08.013 |
0.488 |
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| 2010 |
Masterson LR, Cheng C, Yu T, Tonelli M, Kornev A, Taylor SS, Veglia G. Dynamics connect substrate recognition to catalysis in protein kinase A. Nature Chemical Biology. 6: 821-8. PMID 20890288 DOI: 10.1038/Nchembio.452 |
0.646 |
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| 2010 |
Patel HH, Hamuro LL, Chun BJ, Kawaraguchi Y, Quick A, Rebolledo B, Pennypacker J, Thurston J, Rodriguez-Pinto N, Self C, Olson G, Insel PA, Giles WR, Taylor SS, Roth DM. Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function. The Journal of Biological Chemistry. 285: 27632-40. PMID 20581396 DOI: 10.1074/Jbc.M110.146589 |
0.388 |
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| 2010 |
Sjoberg TJ, Kornev AP, Taylor SS. Dissecting the cAMP-inducible allosteric switch in protein kinase A RIalpha. Protein Science : a Publication of the Protein Society. 19: 1213-21. PMID 20512974 DOI: 10.1002/Pro.400 |
0.831 |
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| 2010 |
Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, ... ... Taylor SS, et al. Climate change and the integrity of science. Science (New York, N.Y.). 328: 689-90. PMID 20448167 DOI: 10.1126/Science.328.5979.689 |
0.421 |
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| 2010 |
Taylor SS, Kornev AP. Yet another "active" pseudokinase, Erb3. Proceedings of the National Academy of Sciences of the United States of America. 107: 8047-8. PMID 20421461 DOI: 10.1073/Pnas.1003436107 |
0.529 |
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| 2010 |
McNicholl ET, Das R, SilDas S, Taylor SS, Melacini G. Communication between tandem cAMP binding domains in the regulatory subunit of protein kinase A-Ialpha as revealed by domain-silencing mutations. The Journal of Biological Chemistry. 285: 15523-37. PMID 20202931 DOI: 10.1074/Jbc.M110.105783 |
0.522 |
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| 2010 |
Anand GS, Krishnamurthy S, Bishnoi T, Kornev A, Taylor SS, Johnson DA. Cyclic AMP- and (Rp)-cAMPS-induced conformational changes in a complex of the catalytic and regulatory (RI{alpha}) subunits of cyclic AMP-dependent protein kinase. Molecular & Cellular Proteomics : McP. 9: 2225-37. PMID 20167947 DOI: 10.1074/Mcp.M900388-Mcp200 |
0.467 |
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| 2010 |
Sarma GN, Kinderman FS, Kim C, von Daake S, Chen L, Wang BC, Taylor SS. Structure of D-AKAP2:PKA RI complex: insights into AKAP specificity and selectivity. Structure (London, England : 1993). 18: 155-66. PMID 20159461 DOI: 10.1016/J.Str.2009.12.012 |
0.818 |
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| 2010 |
Steichen JM, Iyer GH, Li S, Saldanha SA, Deal MS, Woods VL, Taylor SS. Global consequences of activation loop phosphorylation on protein kinase A. The Journal of Biological Chemistry. 285: 3825-32. PMID 19965870 DOI: 10.1074/Jbc.M109.061820 |
0.807 |
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| 2010 |
Kornev AP, Taylor SS. Defining the conserved internal architecture of a protein kinase. Biochimica Et Biophysica Acta. 1804: 440-4. PMID 19879387 DOI: 10.1016/J.Bbapap.2009.10.017 |
0.499 |
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| 2010 |
Valiev M, Yang J, Adams JA, Taylor SS, Weare JH. Correction to “Phosphorylation Reaction in cAPK Protein Kinase-Free Energy Quantum Mechanical/Molecular Mechanics Simulations” Journal of Physical Chemistry B. 114: 6763-6763. DOI: 10.1021/Jp910239G |
0.347 |
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| 2010 |
Fajer M, Taylor S, McCammon JA. Dynamics of the PKA C-Subunit Major Conformational States Using REXAMD Biophysical Journal. 98: 444a. DOI: 10.1016/J.Bpj.2009.12.2410 |
0.459 |
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| 2010 |
Johnson DA, Akamine P, Radzio-Andzelm E, Madhusudan M, Taylor SS. ChemInform Abstract: Dynamics of cAMP-Dependent Protein Kinase Cheminform. 32: no-no. DOI: 10.1002/CHIN.200140285 |
0.385 |
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| 2009 |
Khavrutskii IV, Grant B, Taylor SS, McCammon JA. A transition path ensemble study reveals a linchpin role for Mg(2+) during rate-limiting ADP release from protein kinase A. Biochemistry. 48: 11532-45. PMID 19886670 DOI: 10.1021/Bi901475G |
0.769 |
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| 2009 |
Cheng CY, Yang J, Taylor SS, Blumenthal DK. Sensing domain dynamics in protein kinase A-I{alpha} complexes by solution X-ray scattering. The Journal of Biological Chemistry. 284: 35916-25. PMID 19837668 DOI: 10.1074/Jbc.M109.059493 |
0.659 |
|
| 2009 |
Eggers CT, Schafer JC, Goldenring JR, Taylor SS. D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling. The Journal of Biological Chemistry. 284: 32869-80. PMID 19797056 DOI: 10.1074/Jbc.M109.022582 |
0.463 |
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| 2009 |
Brown SH, Wu J, Kim C, Alberto K, Taylor SS. Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures. Journal of Molecular Biology. 393: 1070-82. PMID 19748511 DOI: 10.1016/J.Jmb.2009.09.014 |
0.587 |
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| 2009 |
Thompson EE, Kornev AP, Kannan N, Kim C, Ten Eyck LF, Taylor SS. Comparative surface geometry of the protein kinase family. Protein Science : a Publication of the Protein Society. 18: 2016-26. PMID 19610074 DOI: 10.1002/Pro.209 |
0.499 |
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| 2009 |
Romano RA, Kannan N, Kornev AP, Allison CJ, Taylor SS. A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1. Protein Science : a Publication of the Protein Society. 18: 1486-97. PMID 19530248 DOI: 10.1002/Pro.146 |
0.508 |
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| 2009 |
Kennedy EJ, Yang J, Pillus L, Taylor SS, Ghosh G. Identifying critical non-catalytic residues that modulate protein kinase A activity. Plos One. 4: e4746. PMID 19270744 DOI: 10.1371/Journal.Pone.0004746 |
0.516 |
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| 2009 |
Kornev AP, Taylor SS. Pseudokinases: functional insights gleaned from structure. Structure (London, England : 1993). 17: 5-7. PMID 19141276 DOI: 10.1016/J.Str.2008.12.005 |
0.337 |
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| 2009 |
Yang J, Kennedy EJ, Wu J, Deal MS, Pennypacker J, Ghosh G, Taylor SS. Contribution of non-catalytic core residues to activity and regulation in protein kinase A. The Journal of Biological Chemistry. 284: 6241-8. PMID 19122195 DOI: 10.1074/Jbc.M805862200 |
0.562 |
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| 2009 |
Gould CM, Kannan N, Taylor SS, Newton AC. The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail. The Journal of Biological Chemistry. 284: 4921-35. PMID 19091746 DOI: 10.1074/Jbc.M808436200 |
0.558 |
|
| 2009 |
Boettcher AJ, Wu J, Kim C, Yang J, Bruystens J, Cheung N, Pennypacker JK, Blumenthal DA, Kornev AP, Taylor SS. Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase Structure. 19: 265-276. DOI: 10.2210/Pdb3Pvb/Pdb |
0.491 |
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| 2009 |
Kornev AP, Taylor SS, Ten Eyck LF. Correction: A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains Plos Computational Biology. 5. DOI: 10.1371/Annotation/43Fd4Ca3-0996-462C-Ad89-395C369Cbaa2 |
0.32 |
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| 2009 |
Casteel DE, Smith-Nguyen EV, Sankaran B, Spraggon G, Hampton EN, Pilz RB, Taylor SS, Kim C. The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring Bmc Pharmacology. 9: P6. DOI: 10.1186/1471-2210-9-S1-P6 |
0.527 |
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| 2008 |
Kornev AP, Taylor SS, Ten Eyck LF. A helix scaffold for the assembly of active protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 105: 14377-82. PMID 18787129 DOI: 10.1073/Pnas.0807988105 |
0.509 |
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| 2008 |
Torkamani A, Kannan N, Taylor SS, Schork NJ. Congenital disease SNPs target lineage specific structural elements in protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 105: 9011-6. PMID 18579784 DOI: 10.1073/Pnas.0802403105 |
0.417 |
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| 2008 |
Kannan N, Taylor SS. Rethinking pseudokinases. Cell. 133: 204-5. PMID 18423189 DOI: 10.1016/j.cell.2008.04.005 |
0.338 |
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| 2008 |
Kornev AP, Taylor SS, Ten Eyck LF. A generalized allosteric mechanism for cis-regulated cyclic nucleotide binding domains. Plos Computational Biology. 4: e1000056. PMID 18404204 DOI: 10.1371/Journal.Pcbi.1000056 |
0.466 |
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| 2008 |
Masterson LR, Mascioni A, Traaseth NJ, Taylor SS, Veglia G. Allosteric cooperativity in protein kinase A. Proceedings of the National Academy of Sciences of the United States of America. 105: 506-11. PMID 18178622 DOI: 10.1073/Pnas.0709214104 |
0.534 |
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| 2008 |
Ten Eyck LF, Taylor SS, Kornev AP. Conserved spatial patterns across the protein kinase family. Biochimica Et Biophysica Acta. 1784: 238-43. PMID 18067871 DOI: 10.1016/J.Bbapap.2007.11.002 |
0.52 |
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| 2008 |
Taylor SS, Kim C, Cheng CY, Brown SH, Wu J, Kannan N. Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design. Biochimica Et Biophysica Acta. 1784: 16-26. PMID 17996741 DOI: 10.1016/J.Bbapap.2007.10.002 |
0.735 |
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| 2008 |
Kannan N, Neuwald AF, Taylor SS. Analogous regulatory sites within the alphaC-beta4 loop regions of ZAP-70 tyrosine kinase and AGC kinases. Biochimica Et Biophysica Acta. 1784: 27-32. PMID 17977811 DOI: 10.1016/J.Bbapap.2007.09.007 |
0.517 |
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| 2007 |
Kannan N, Wu J, Anand GS, Yooseph S, Neuwald AF, Venter JC, Taylor SS. Evolution of allostery in the cyclic nucleotide binding module. Genome Biology. 8: R264. PMID 18076763 DOI: 10.1186/Gb-2007-8-12-R264 |
0.627 |
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| 2007 |
Valiev M, Yang J, Adams JA, Taylor SS, Weare JH. Phosphorylation reaction in cAPK protein kinase-free energy quantum mechanical/molecular mechanics simulations. The Journal of Physical Chemistry. B. 111: 13455-64. PMID 17983217 DOI: 10.1021/Jp074853Q |
0.393 |
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| 2007 |
Anand GS, Hotchko M, Brown SH, Ten Eyck LF, Komives EA, Taylor SS. R-subunit isoform specificity in protein kinase A: distinct features of protein interfaces in PKA types I and II by amide H/2H exchange mass spectrometry. Journal of Molecular Biology. 374: 487-99. PMID 17942118 DOI: 10.1016/J.Jmb.2007.09.035 |
0.511 |
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| 2007 |
Wu J, Brown SH, von Daake S, Taylor SS. PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity. Science (New York, N.Y.). 318: 274-9. PMID 17932298 DOI: 10.1126/Science.1146447 |
0.565 |
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| 2007 |
Alto NM, Weflen AW, Rardin MJ, Yarar D, Lazar CS, Tonikian R, Koller A, Taylor SS, Boone C, Sidhu SS, Schmid SL, Hecht GA, Dixon JE. The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. The Journal of Cell Biology. 178: 1265-78. PMID 17893247 DOI: 10.1083/Jcb.200705021 |
0.538 |
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| 2007 |
Kim C, Cheng CY, Saldanha SA, Taylor SS. PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell. 130: 1032-43. PMID 17889648 DOI: 10.1016/J.Cell.2007.07.018 |
0.713 |
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| 2007 |
Martin BR, Deerinck TJ, Ellisman MH, Taylor SS, Tsien RY. Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells. Chemistry & Biology. 14: 1031-42. PMID 17884635 DOI: 10.1016/J.Chembiol.2007.07.017 |
0.562 |
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| 2007 |
Anand G, Taylor SS, Johnson DA. Cyclic-AMP and pseudosubstrate effects on type-I A-kinase regulatory and catalytic subunit binding kinetics. Biochemistry. 46: 9283-91. PMID 17658893 DOI: 10.1021/Bi700421H |
0.536 |
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| 2007 |
Humphries KM, Pennypacker JK, Taylor SS. Redox regulation of cAMP-dependent protein kinase signaling: kinase versus phosphatase inactivation. The Journal of Biological Chemistry. 282: 22072-9. PMID 17548350 DOI: 10.1074/Jbc.M702582200 |
0.4 |
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| 2007 |
Navarro L, Koller A, Nordfelth R, Wolf-Watz H, Taylor S, Dixon JE. Identification of a molecular target for the Yersinia protein kinase A. Molecular Cell. 26: 465-77. PMID 17531806 DOI: 10.1016/J.Molcel.2007.04.025 |
0.662 |
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| 2007 |
Lim CJ, Han J, Yousefi N, Ma Y, Amieux PS, McKnight GS, Taylor SS, Ginsberg MH. Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins. Nature Cell Biology. 9: 415-21. PMID 17369818 DOI: 10.1038/Ncb1561 |
0.519 |
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| 2007 |
Kannan N, Taylor SS, Zhai Y, Venter JC, Manning G. Structural and functional diversity of the microbial kinome. Plos Biology. 5: e17. PMID 17355172 DOI: 10.1371/Journal.Pbio.0050017 |
0.645 |
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| 2007 |
Yooseph S, Sutton G, Rusch DB, Halpern AL, Williamson SJ, Remington K, Eisen JA, Heidelberg KB, Manning G, Li W, Jaroszewski L, Cieplak P, Miller CS, Li H, Mashiyama ST, ... ... Taylor SS, et al. The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. Plos Biology. 5: e16. PMID 17355171 DOI: 10.1371/Journal.Pbio.0050016 |
0.659 |
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| 2007 |
Schauble S, King CC, Darshi M, Koller A, Shah K, Taylor SS. Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit. The Journal of Biological Chemistry. 282: 14952-9. PMID 17242405 DOI: 10.1074/Jbc.M609221200 |
0.835 |
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| 2007 |
Kannan N, Haste N, Taylor SS, Neuwald AF. The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module. Proceedings of the National Academy of Sciences of the United States of America. 104: 1272-7. PMID 17227859 DOI: 10.1073/Pnas.0610251104 |
0.488 |
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| 2007 |
Das R, Esposito V, Abu-Abed M, Anand GS, Taylor SS, Melacini G. cAMP activation of PKA defines an ancient signaling mechanism Proceedings of the National Academy of Sciences of the United States of America. 104: 93-98. PMID 17182741 DOI: 10.1073/Pnas.0609033103 |
0.501 |
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| 2006 |
Saldanha SA, Kaler G, Cottam HB, Abagyan R, Taylor SS. Assay principle for modulators of protein-protein interactions and its application to non-ATP-competitive ligands targeting protein kinase A. Analytical Chemistry. 78: 8265-72. PMID 17165815 DOI: 10.1021/Ac061104G |
0.456 |
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| 2006 |
Kornev AP, Haste NM, Taylor SS, Eyck LF. Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism. Proceedings of the National Academy of Sciences of the United States of America. 103: 17783-8. PMID 17095602 DOI: 10.1073/Pnas.0607656103 |
0.502 |
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| 2006 |
Kinderman FS, Kim C, von Daake S, Ma Y, Pham BQ, Spraggon G, Xuong NH, Jennings PA, Taylor SS. A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Molecular Cell. 24: 397-408. PMID 17081990 DOI: 10.1016/J.Molcel.2006.09.015 |
0.839 |
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| 2006 |
Cranston AN, Carniti C, Oakhill K, Radzio-Andzelm E, Stone EA, McCallion AS, Hodgson S, Clarke S, Mondellini P, Leyland J, Pierotti MA, Whittaker J, Taylor SS, Bongarzone I, Ponder BA. RET is constitutively activated by novel tandem mutations that alter the active site resulting in multiple endocrine neoplasia type 2B. Cancer Research. 66: 10179-87. PMID 17047083 DOI: 10.1158/0008-5472.Can-06-0884 |
0.392 |
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| 2006 |
Esposito V, Sjoberg T, Das R, Brown S, Taylor SS, Melacini G. NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit [62] Journal of Biomolecular Nmr. 36: 64. PMID 17016670 DOI: 10.1007/S10858-006-9050-9 |
0.818 |
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| 2006 |
Kim C, Vigil D, Anand G, Taylor SS. Structure and dynamics of PKA signaling proteins. European Journal of Cell Biology. 85: 651-4. PMID 16647784 DOI: 10.1016/J.Ejcb.2006.02.004 |
0.683 |
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| 2006 |
Vigil D, Blumenthal DK, Taylor SS, Trewhella J. Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms. Journal of Molecular Biology. 357: 880-9. PMID 16460759 DOI: 10.1016/J.Jmb.2006.01.006 |
0.737 |
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| 2006 |
Niedner RH, Buzko OV, Haste NM, Taylor A, Gribskov M, Taylor SS. Protein kinase resource: an integrated environment for phosphorylation research. Proteins. 63: 78-86. PMID 16435372 DOI: 10.1002/Prot.20825 |
0.445 |
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| 2006 |
Gullingsrud J, Kim C, Taylor SS, McCammon JA. Dynamic binding of PKA regulatory subunit RIα Structure. 14: 141-149. PMID 16407073 DOI: 10.1016/J.Str.2005.09.019 |
0.489 |
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| 2006 |
Vigil D, Lin JH, Sotriffer CA, Pennypacker JK, McCammon JA, Taylor SS. A simple electrostatic switch important in the activation of type I protein kinase A by cyclic AMP. Protein Science : a Publication of the Protein Society. 15: 113-21. PMID 16322564 DOI: 10.1110/Ps.051723606 |
0.783 |
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| 2006 |
Taylor SS, Ghosh G. Protein kinases: Catalysis and regulation Current Opinion in Structural Biology. 16: 665-667. DOI: 10.1016/J.Sbi.2006.11.001 |
0.498 |
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| 2005 |
Burns-Hamuro LL, Hamuro Y, Kim JS, Sigala P, Fayos R, Stranz DD, Jennings PA, Taylor SS, Woods VL. Distinct interaction modes of an AKAP bound to two regulatory subunit isoforms of protein kinase A revealed by amide hydrogen/deuterium exchange. Protein Science : a Publication of the Protein Society. 14: 2982-92. PMID 16260760 DOI: 10.1110/Ps.051687305 |
0.47 |
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| 2005 |
Wu J, Yang J, Kannan N, Madhusudan, Xuong NH, Ten Eyck LF, Taylor SS. Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix. Protein Science : a Publication of the Protein Society. 14: 2871-9. PMID 16253959 DOI: 10.1110/Ps.051715205 |
0.702 |
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| 2005 |
Taylor SS, Kim C, Vigil D, Haste NM, Yang J, Wu J, Anand GS. Dynamics of signaling by PKA. Biochimica Et Biophysica Acta. 1754: 25-37. PMID 16214430 DOI: 10.1016/J.Bbapap.2005.08.024 |
0.787 |
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| 2005 |
Taylor SS, Haste NM, Ghosh G. PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking. Cell. 122: 823-5. PMID 16179248 DOI: 10.1016/J.Cell.2005.09.007 |
0.505 |
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| 2005 |
Zhang J, Hupfeld CJ, Taylor SS, Olefsky JM, Tsien RY. Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes. Nature. 437: 569-73. PMID 16177793 DOI: 10.1038/Nature04140 |
0.389 |
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| 2005 |
Vigil D, Blumenthal DK, Taylor SS, Trewhella J. The conformationally dynamic C helix of the RIalpha subunit of protein kinase A mediates isoform-specific domain reorganization upon C subunit binding. The Journal of Biological Chemistry. 280: 35521-7. PMID 16109722 DOI: 10.1074/Jbc.M506769200 |
0.757 |
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| 2005 |
Iyer GH, Garrod S, Woods VL, Taylor SS. Catalytic independent functions of a protein kinase as revealed by a kinase-dead mutant: study of the Lys72His mutant of cAMP-dependent kinase. Journal of Molecular Biology. 351: 1110-22. PMID 16054648 DOI: 10.1016/J.Jmb.2005.06.011 |
0.573 |
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| 2005 |
Kim C, Xuong NH, Taylor SS. Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA. Science (New York, N.Y.). 307: 690-6. PMID 15692043 DOI: 10.1126/Science.1104607 |
0.725 |
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| 2005 |
Yang J, Garrod SM, Deal MS, Anand GS, Woods VL, Taylor S. Allosteric network of cAMP-dependent protein kinase revealed by mutation of Tyr204 in the P+1 loop. Journal of Molecular Biology. 346: 191-201. PMID 15663937 DOI: 10.1016/J.Jmb.2004.11.030 |
0.517 |
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| 2005 |
Sastri M, Barraclough DM, Carmichael PT, Taylor SS. A-kinase-interacting protein localizes protein kinase A in the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 102: 349-54. PMID 15630084 DOI: 10.1073/Pnas.0408608102 |
0.709 |
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| 2005 |
Berman HM, Ten Eyck LF, Goodsell DS, Haste NM, Kornev A, Taylor SS. The cAMP binding domain: An ancient signaling module Proceedings of the National Academy of Sciences of the United States of America. 102: 45-50. PMID 15618393 DOI: 10.1073/Pnas.0408579102 |
0.486 |
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| 2005 |
Iyer GH, Moore MJ, Taylor SS. Consequences of lysine 72 mutation on the phosphorylation and activation state of cAMP-dependent kinase. The Journal of Biological Chemistry. 280: 8800-7. PMID 15618230 DOI: 10.1074/Jbc.M407586200 |
0.556 |
|
| 2005 |
Humphries KM, Deal MS, Taylor SS. Enhanced dephosphorylation of cAMP-dependent protein kinase by oxidation and thiol modification. The Journal of Biological Chemistry. 280: 2750-8. PMID 15533936 DOI: 10.1074/Jbc.M410242200 |
0.533 |
|
| 2005 |
Zheng J, Trafny EA, Knighton DR, Xuong NH, Taylor SS, Ten Eyck LF, Sowadski JM. 2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor. Acta Crystallographica. Section D, Biological Crystallography. 49: 362-5. PMID 15299527 DOI: 10.1107/S0907444993000423 |
0.46 |
|
| 2005 |
Knighton DR, Bell SM, Zheng J, Ten Eyck LF, Xuong NH, Taylor SS, Sowadski JM. 2.0 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with a peptide inhibitor and detergent. Acta Crystallographica. Section D, Biological Crystallography. 49: 357-61. PMID 15299526 DOI: 10.1107/S0907444993000502 |
0.549 |
|
| 2005 |
Karlsson R, Zheng J, Xuong N, Taylor SS, Sowadski JM. Structure of the mammalian catalytic subunit of cAMP-dependent protein kinase and an inhibitor peptide displays an open conformation. Acta Crystallographica. Section D, Biological Crystallography. 49: 381-8. PMID 15299513 DOI: 10.1107/S0907444993002306 |
0.629 |
|
| 2004 |
Burns-Hamuro LL, Barraclough DM, Taylor SS. Identification and functional analysis of dual-specific A kinase-anchoring protein-2. Methods in Enzymology. 390: 354-374. PMID 15488188 DOI: 10.1016/S0076-6879(04)90022-5 |
0.478 |
|
| 2004 |
Nolen B, Taylor S, Ghosh G. Regulation of protein kinases; controlling activity through activation segment conformation. Molecular Cell. 15: 661-75. PMID 15350212 DOI: 10.1016/J.Molcel.2004.08.024 |
0.463 |
|
| 2004 |
Wu J, Brown S, Xuong NH, Taylor SS. RIalpha subunit of PKA: a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B. Structure (London, England : 1993). 12: 1057-65. PMID 15274925 DOI: 10.1016/J.Str.2004.03.022 |
0.696 |
|
| 2004 |
Hamuro Y, Anand GS, Kim JS, Juliano C, Stranz DD, Taylor SS, Woods VL. Mapping intersubunit interactions of the regulatory subunit (RIalpha) in the type I holoenzyme of protein kinase A by amide hydrogen/deuterium exchange mass spectrometry (DXMS). Journal of Molecular Biology. 340: 1185-96. PMID 15236976 DOI: 10.1016/J.Jmb.2004.05.042 |
0.506 |
|
| 2004 |
Wu J, Jones JM, Nguyen-Huu X, Ten Eyck LF, Taylor SS. Crystal structures of RIalpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP. Biochemistry. 43: 6620-9. PMID 15157095 DOI: 10.1021/Bi0302503 |
0.522 |
|
| 2004 |
Vigil D, Blumenthal DK, Brown S, Taylor SS, Trewhella J. Differential effects of substrate on type I and type II PKA holoenzyme dissociation. Biochemistry. 43: 5629-36. PMID 15134437 DOI: 10.1021/Bi0499157 |
0.72 |
|
| 2004 |
Vigil D, Blumenthal DK, Heller WT, Brown S, Canaves JM, Taylor SS, Trewhella J. Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions. Journal of Molecular Biology. 337: 1183-94. PMID 15046986 DOI: 10.1016/J.Jmb.2004.02.028 |
0.764 |
|
| 2004 |
Taylor SS, Yang J, Wu J, Haste NM, Radzio-Andzelm E, Anand G. PKA: a portrait of protein kinase dynamics. Biochimica Et Biophysica Acta. 1697: 259-69. PMID 15023366 DOI: 10.1016/J.Bbapap.2003.11.029 |
0.566 |
|
| 2004 |
Heller WT, Vigil D, Brown S, Blumenthal DK, Taylor SS, Trewhella J. C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change. The Journal of Biological Chemistry. 279: 19084-90. PMID 14985329 DOI: 10.1074/Jbc.M313405200 |
0.71 |
|
| 2004 |
Yang J, Ten Eyck LF, Xuong NH, Taylor SS. Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism. Journal of Molecular Biology. 336: 473-87. PMID 14757059 DOI: 10.1016/J.Jmb.2003.11.044 |
0.721 |
|
| 2004 |
Akamine P, Madhusudan, Brunton LL, Ou HD, Canaves JM, Xuong NH, Taylor SS. Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit. Biochemistry. 43: 85-96. PMID 14705934 DOI: 10.1021/Bi035042P |
0.863 |
|
| 2004 |
Zawadzki KM, Taylor SS. cAMP-dependent protein kinase regulatory subunit type IIbeta: active site mutations define an isoform-specific network for allosteric signaling by cAMP. The Journal of Biological Chemistry. 279: 7029-36. PMID 14625280 DOI: 10.1074/Jbc.M310804200 |
0.852 |
|
| 2003 |
Anand GS, Law D, Mandell JG, Snead AN, Tsigelny I, Taylor SS, Ten Eyck LF, Komives EA. Identification of the protein kinase A regulatory RIalpha-catalytic subunit interface by amide H/2H exchange and protein docking. Proceedings of the National Academy of Sciences of the United States of America. 100: 13264-9. PMID 14583592 DOI: 10.1073/Pnas.2232255100 |
0.465 |
|
| 2003 |
Gisler SM, Madjdpour C, Bacic D, Pribanic S, Taylor SS, Biber J, Murer H. PDZK1: II. an anchoring site for the PKA-binding protein D-AKAP2 in renal proximal tubular cells. Kidney International. 64: 1746-54. PMID 14531807 DOI: 10.1046/J.1523-1755.2003.00267.X |
0.398 |
|
| 2003 |
Zawadzki KM, Hamuro Y, Kim JS, Garrod S, Stranz DD, Taylor SS, Woods VL. Dissecting interdomain communication within cAPK regulatory subunit type IIβ using enhanced amide hydrogen/deuterium exchange mass spectrometry (DXMS) Protein Science. 12: 1980-1990. PMID 12930997 DOI: 10.1110/Ps.03166903 |
0.836 |
|
| 2003 |
Banky P, Roy M, Newlon MG, Morikis D, Haste NM, Taylor SS, Jennings PA. Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. Journal of Molecular Biology. 330: 1117-29. PMID 12860132 DOI: 10.1016/S0022-2836(03)00552-7 |
0.811 |
|
| 2003 |
Zawadzki KM, Pan CP, Barkley MD, Johnson D, Taylor SS. Endogenous tryptophan residues of cAPK regulatory subunit type IIbeta reveal local variations in environments and dynamics. Proteins. 51: 552-61. PMID 12784214 DOI: 10.1002/Prot.10326 |
0.84 |
|
| 2003 |
Burns LL, Canaves JM, Pennypacker JK, Blumenthal DK, Taylor SS. Isoform specific differences in binding of a dual-specificity A-kinase anchoring protein to type I and type II regulatory subunits of PKA. Biochemistry. 42: 5754-63. PMID 12741833 DOI: 10.1021/Bi0265729 |
0.502 |
|
| 2003 |
Hamuro Y, Zawadzki KM, Kim JS, Stranz DD, Taylor SS, Woods VL. Dynamics of cAPK type IIbeta activation revealed by enhanced amide H/2H exchange mass spectrometry (DXMS). Journal of Molecular Biology. 327: 1065-76. PMID 12662931 DOI: 10.1016/S0022-2836(03)00234-1 |
0.848 |
|
| 2003 |
Kammerer S, Burns-Hamuro LL, Ma Y, Hamon SC, Canaves JM, Shi MM, Nelson MR, Sing CF, Cantor CR, Taylor SS, Braun A. Amino acid variant in the kinase binding domain of dual-specific A kinase-anchoring protein 2: a disease susceptibility polymorphism. Proceedings of the National Academy of Sciences of the United States of America. 100: 4066-71. PMID 12646697 DOI: 10.1073/Pnas.2628028100 |
0.393 |
|
| 2003 |
Burns-Hamuro LL, Ma Y, Kammerer S, Reineke U, Self C, Cook C, Olson GL, Cantor CR, Braun A, Taylor SS. Designing isoform-specific peptide disruptors of protein kinase A localization. Proceedings of the National Academy of Sciences of the United States of America. 100: 4072-7. PMID 12646696 DOI: 10.1073/Pnas.2628038100 |
0.436 |
|
| 2003 |
Akamine P, Madhusudan, Wu J, Xuong NH, Ten Eyck LF, Taylor SS. Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure. Journal of Molecular Biology. 327: 159-71. PMID 12614615 DOI: 10.1016/S0022-2836(02)01446-8 |
0.848 |
|
| 2003 |
Moore MJ, Adams JA, Taylor SS. Structural basis for peptide binding in protein kinase A. Role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop. The Journal of Biological Chemistry. 278: 10613-8. PMID 12499371 DOI: 10.1074/Jbc.M210807200 |
0.421 |
|
| 2002 |
Taylor SS, Kim CW, Cheng CY, Kannan N, Sastri M, Eggers CW, Wu J. Fifty Years Since the Discovery of PKA. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4123. PMID 29430987 DOI: 10.1096/Fasebj.22.1_Supplement.412.3 |
0.71 |
|
| 2002 |
Chatterji A, Burns LL, Taylor SS, Lomonossoff GP, Johnson JE, Lin T, Porta C. Cowpea mosaic virus: From the presentation of antigenic peptides to the display of active biomaterials Intervirology. 45: 362-370. PMID 12602357 DOI: 10.1159/000067929 |
0.301 |
|
| 2002 |
Anand GS, Hughes CA, Jones JM, Taylor SS, Komives EA. Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A. Journal of Molecular Biology. 323: 377-86. PMID 12381327 DOI: 10.1016/S0022-2836(02)00919-1 |
0.475 |
|
| 2002 |
Moore MJ, Kanter JR, Jones KC, Taylor SS. Phosphorylation of the catalytic subunit of protein kinase A. Autophosphorylation versus phosphorylation by phosphoinositide-dependent kinase-1. The Journal of Biological Chemistry. 277: 47878-84. PMID 12372837 DOI: 10.1074/Jbc.M204970200 |
0.548 |
|
| 2002 |
Kuhn P, Lesley SA, Mathews II, Canaves JM, Brinen LS, Dai X, Deacon AM, Elsliger MA, Eshaghi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Guda C, Hodgson KO, ... ... Taylor SS, et al. Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 A resolution. Proteins. 49: 142-5. PMID 12211025 DOI: 10.1002/Prot.10202 |
0.359 |
|
| 2002 |
Hamuro Y, Burns LL, Canaves JM, Hoffman RC, Taylor SS, Woods VL. Domain organization of D-AKAP2 revealed by enhanced deuterium exchange-mass spectrometry (DXMS) Journal of Molecular Biology. 321: 703-714. PMID 12206784 DOI: 10.1016/S0022-2836(02)00419-9 |
0.486 |
|
| 2002 |
Lesley SA, Kuhn P, Godzik A, Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, ... ... Taylor SS, et al. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proceedings of the National Academy of Sciences of the United States of America. 99: 11664-9. PMID 12193646 DOI: 10.1073/Pnas.142413399 |
0.312 |
|
| 2002 |
Humphries KM, Juliano C, Taylor SS. Regulation of cAMP-dependent protein kinase activity by glutathionylation. The Journal of Biological Chemistry. 277: 43505-11. PMID 12189155 DOI: 10.1074/Jbc.M207088200 |
0.475 |
|
| 2002 |
Ma Y, Taylor S. A 15-residue bifunctional element in D-AKAP1 is required for both endoplasmic reticulum and mitochondrial targeting. The Journal of Biological Chemistry. 277: 27328-36. PMID 11994283 DOI: 10.1074/Jbc.M201421200 |
0.338 |
|
| 2002 |
Madhusudan, Akamine P, Xuong NH, Taylor SS. Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase. Nature Structural Biology. 9: 273-7. PMID 11896404 DOI: 10.1038/Nsb780 |
0.84 |
|
| 2002 |
Li F, Gangal M, Juliano C, Gorfain E, Taylor SS, Johnson DA. Evidence for an internal entropy contribution to phosphoryl transfer: A study of domain closure, backbone flexibility, and the catalytic cycle of cAMP-dependent protein kinase Journal of Molecular Biology. 315: 459-469. PMID 11786025 DOI: 10.1006/Jmbi.2001.5256 |
0.543 |
|
| 2002 |
Johnson DA, Akamine P, Radzio-Andzelm E, Madhusudan M, Taylor SS. Dynamics of cAMP-dependent protein kinase. Chemical Reviews. 101: 2243-70. PMID 11749372 DOI: 10.1021/Cr000226K |
0.811 |
|
| 2002 |
Canaves JM, Taylor SS. Classification and phylogenetic analysis of the cAMP-dependent protein kinase regulatory subunit family Journal of Molecular Evolution. 54: 17-29. PMID 11734894 DOI: 10.1007/S00239-001-0013-1 |
0.416 |
|
| 2001 |
Zhang J, Ma Y, Taylor SS, Tsien RY. Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering. Proceedings of the National Academy of Sciences of the United States of America. 98: 14997-5002. PMID 11752448 DOI: 10.1073/Pnas.211566798 |
0.501 |
|
| 2001 |
Perkins GA, Wang L, Huang LJ, Humphries K, Yao VJ, Martone M, Deerinck TJ, Barraclough DM, Violin JD, Smith D, Newton A, Scott JD, Taylor SS, Ellisman MH. PKA, PKC, and AKAP localization in and around the neuromuscular junction. Bmc Neuroscience. 2: 17. PMID 11716788 DOI: 10.1186/1471-2202-2-17 |
0.566 |
|
| 2001 |
Diller TC, Madhusudan, Xuong NH, Taylor SS. Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit. Structure (London, England : 1993). 9: 73-82. PMID 11342137 DOI: 10.1016/S0969-2126(00)00556-6 |
0.858 |
|
| 2001 |
Wong CF, Hünenberger PH, Akamine P, Narayana N, Diller T, McCammon JA, Taylor S, Xuong NH. Computational analysis of PKA-balanol interactions Journal of Medicinal Chemistry. 44: 1530-1539. PMID 11334563 DOI: 10.1021/Jm000443D |
0.83 |
|
| 2001 |
Wang L, Sunahara RK, Krumins A, Perkins G, Crochiere ML, Mackey M, Bell S, Ellisman MH, Taylor SS. Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein. Proceedings of the National Academy of Sciences of the United States of America. 98: 3220-5. PMID 11248059 DOI: 10.1073/Pnas.051633398 |
0.593 |
|
| 2001 |
Herrgård S, Jambeck P, Taylor SS, Subramaniam S. Domain architecture of a Caenorhabditis elegans AKAP suggests a novel AKAP function. Febs Letters. 486: 107-11. PMID 11113448 DOI: 10.1016/S0014-5793(00)02201-8 |
0.476 |
|
| 2001 |
Li F, Gangal M, Jones JM, Deich J, Lovett KE, Taylor SS, Johnson DA. Consequences of cAMP and catalytic-subunit binding on the flexibility of the A-kinase regulatory subunit. Biochemistry. 39: 15626-32. PMID 11112551 DOI: 10.1021/Bi002196L |
0.538 |
|
| 2001 |
Cheng X, Phelps C, Taylor SS. Differential Binding of cAMP-dependent Protein Kinase Regulatory Subunit Isoforms Iα and IIβ to the Catalytic Subunit Journal of Biological Chemistry. 276: 4102-4108. PMID 11110787 DOI: 10.1074/Jbc.M006447200 |
0.519 |
|
| 2000 |
Cànaves JM, Leon DA, Taylor SS. Consequences of cAMP-binding site mutations on the structural stability of the type I regulatory subunit of cAMP-dependent protein kinase. Biochemistry. 39: 15022-31. PMID 11106480 DOI: 10.1021/Bi001563Q |
0.484 |
|
| 2000 |
Diller TC, Xuong NH, Taylor SS. Type II beta regulatory subunit of cAMP-dependent protein kinase: purification strategies to optimize crystallization. Protein Expression and Purification. 20: 357-64. PMID 11087674 DOI: 10.1006/Prep.2000.1312 |
0.815 |
|
| 2000 |
Banky P, Newlon MG, Roy M, Garrod S, Taylor SS, Jennings PA. Isoform-specific differences between the type Iα and IIα cyclic AMP-dependent protein kinase anchoring domains revealed by solution NMR Journal of Biological Chemistry. 275: 35146-35152. PMID 10899163 DOI: 10.1074/Jbc.M003961200 |
0.823 |
|
| 2000 |
Aimes RT, Hemmer W, Taylor SS. Serine-53 at the tip of the glycine-rich loop of cAMP-dependent protein kinase: Role in catalysis, P-site specificity, and interaction with inhibitors Biochemistry. 39: 8325-8332. PMID 10889042 DOI: 10.1021/Bi992800W |
0.522 |
|
| 2000 |
Leon DA, Canaves JM, Taylor SS. Probing the multidomain structure of the type I regulatory subunit of cAMP-dependent protein kinase using mutational analysis: Role and environment of endogenous tryptophans Biochemistry. 39: 5662-5671. PMID 10801316 DOI: 10.1021/Bi992819Z |
0.531 |
|
| 2000 |
Zaccolo M, De Giorgi F, Cho CY, Feng L, Knapp T, Negulescu PA, Taylor SS, Tsien RY, Pozzan T. A genetically encoded, fluorescent indicator for cyclic AMP in living cells. Nature Cell Biology. 2: 25-9. PMID 10620803 DOI: 10.1038/71345 |
0.368 |
|
| 1999 |
Gangal M, Clifford T, Deich J, Cheng X, Taylor SS, Johnson DA. Mobilization of the A-kinase N-myristate through an isoform-specific intermolecular switch. Proceedings of the National Academy of Sciences of the United States of America. 96: 12394-9. PMID 10535933 DOI: 10.1073/Pnas.96.22.12394 |
0.423 |
|
| 1999 |
Tsigelny I, Greenberg JP, Cox S, Nichols WL, Taylor SS, Ten Eyck LF. 600 ps molecular dynamics reveals stable substructures and flexible hinge points in cAMP dependent protein kinase. Biopolymers. 50: 513-24. PMID 10479734 DOI: 10.1002/(Sici)1097-0282(19991015)50:5<513::Aid-Bip5>3.0.Co;2-I |
0.45 |
|
| 1999 |
Taylor SS, Radzio-Andzelm E, Cheng X, Ten Eyck L, Narayana N. Catalytic subunit of cyclic AMP-dependent protein kinase: structure and dynamics of the active site cleft. Pharmacology & Therapeutics. 82: 133-41. PMID 10454192 DOI: 10.1016/S0163-7258(99)00007-8 |
0.536 |
|
| 1999 |
Setyawan J, Koide K, Diller TC, Bunnage ME, Taylor SS, Nicolaou KC, Brunton LL. Inhibition of protein kinases by balanol: specificity within the serine/threonine protein kinase subfamily. Molecular Pharmacology. 56: 370-6. PMID 10419556 DOI: 10.1124/Mol.56.2.370 |
0.83 |
|
| 1999 |
Smith CM, Radzio-Andzelm E, Akamine P, Taylor SS. The catalytic subunit of cAMP-dependent protein kinase: prototype for an extended network of communication. Progress in Biophysics and Molecular Biology. 71: 313-41. PMID 10354702 DOI: 10.1016/S0079-6107(98)00059-5 |
0.832 |
|
| 1999 |
Huang LJ, Wang L, Ma Y, Durick K, Perkins G, Deerinck TJ, Ellisman MH, Taylor SS. NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum. The Journal of Cell Biology. 145: 951-9. PMID 10352013 DOI: 10.1083/Jcb.145.5.951 |
0.55 |
|
| 1999 |
Hauer JA, Taylor SS, Johnson DA. Binding-dependent disorder-order transition in PKI alpha: a fluorescence anisotropy study. Biochemistry. 38: 6774-80. PMID 10346898 DOI: 10.1021/Bi983074K |
0.413 |
|
| 1999 |
Herberg FW, Doyle ML, Cox S, Taylor SS. Dissection of the nucleotide and metal-phosphate binding sites in cAMP-dependent protein kinase. Biochemistry. 38: 6352-60. PMID 10320366 DOI: 10.1021/Bi982672W |
0.432 |
|
| 1999 |
Harada H, Becknell B, Wilm M, Mann M, Huang LJ, Taylor SS, Scott JD, Korsmeyer SJ. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Molecular Cell. 3: 413-22. PMID 10230394 DOI: 10.1016/S1097-2765(00)80469-4 |
0.505 |
|
| 1999 |
Hauer JA, Barthe P, Taylor SS, Parello J, Padilla A. Two well-defined motifs in the cAMP-dependent protein kinase inhibitor (PKIalpha) correlate with inhibitory and nuclear export function. Protein Science : a Publication of the Protein Society. 8: 545-53. PMID 10091657 DOI: 10.1110/Ps.8.3.545 |
0.522 |
|
| 1999 |
Narayana N, Diller TC, Koide K, Bunnage ME, Nicolaou KC, Brunton LL, Xuong NH, Ten Eyck LF, Taylor SS. Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase. Biochemistry. 38: 2367-76. PMID 10029530 DOI: 10.2210/Pdb1Bx6/Pdb |
0.823 |
|
| 1999 |
Hünenberger PH, Helms V, Narayana N, Taylor SS, McCammon JA. Determinants of ligand binding to cAMP-dependent protein kinase. Biochemistry. 38: 2358-66. PMID 10029529 DOI: 10.1021/Bi982064G |
0.48 |
|
| 1999 |
Manoj N, Srinivas VR, Surolia A, Vijayan M, Suguna K, Ravishankar R, Schwarzenbacher R, Zeth K, Diederichs, Kostner GM, Gries A, Laggner P, Prassl R, Madhusudan, Akamine P, ... ... Taylor SS, et al. Contributory presentations/posters Journal of Biosciences. 24: 33-198. DOI: 10.1007/Bf02989373 |
0.746 |
|
| 1998 |
Narayana N, Akamine P, Xuong NH, Taylor SS. Crystallization and preliminary X-ray analysis of the unliganded recombinant catalytic subunit of cAMP-dependent protein kinase Acta Crystallographica Section D: Biological Crystallography. 54: 1401-1404. PMID 10089519 DOI: 10.1107/S0907444998005770 |
0.811 |
|
| 1998 |
Banky P, Huang LJ, Taylor SS. Dimerization/docking domain of the type Ialpha regulatory subunit of cAMP-dependent protein kinase. Requirements for dimerization and docking are distinct but overlapping. The Journal of Biological Chemistry. 273: 35048-55. PMID 9857038 DOI: 10.1074/Jbc.273.52.35048 |
0.826 |
|
| 1998 |
Struppe J, Komives EA, Taylor SS, Vold RR. 2H NMR studies of a myristoylated peptide in neutral and acidic phospholipid bicelles. Biochemistry. 37: 15523-7. PMID 9799515 DOI: 10.1021/Bi981326B |
0.36 |
|
| 1998 |
Cheng X, Shaltiel S, Taylor SS. Mapping substrate-induced conformational changes in cAMP-dependent protein kinase by protein footprinting Biochemistry. 37: 14005-14013. PMID 9760235 DOI: 10.1021/Bi981057P |
0.505 |
|
| 1998 |
Huang LJS, Taylor SS. Dissecting cAMP binding domain A in the R1α subunit of cAMP-dependent protein kinase: Distinct subsites for recognition of cAMP and the catalytic subunit Journal of Biological Chemistry. 273: 26739-26746. PMID 9756917 DOI: 10.1074/Jbc.273.41.26739 |
0.502 |
|
| 1998 |
Gangal M, Cox S, Lew J, Clifford T, Garrod SM, Aschbaher M, Taylor SS, Johnson DA. Backbone flexibility of five sites on the catalytic subunit of cAMP- dependent protein kinase in the open and closed conformations Biochemistry. 37: 13728-13735. PMID 9753461 DOI: 10.1021/Bi980560Z |
0.494 |
|
| 1998 |
Cheng X, Ma Y, Moore M, Hemmings BA, Taylor SS. Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 95: 9849-54. PMID 9707564 DOI: 10.1073/Pnas.95.17.9849 |
0.551 |
|
| 1998 |
de Lecea L, Criado JR, Rivera S, Wen W, Soriano E, Henriksen SJ, Taylor SS, Gall CM, Sutcliffe JG. Endogenous protein kinase A inhibitor (PKIalpha) modulates synaptic activity. Journal of Neuroscience Research. 53: 269-78. PMID 9698155 DOI: 10.1002/(Sici)1097-4547(19980801)53:3<269::Aid-Jnr1>3.0.Co;2-8 |
0.366 |
|
| 1998 |
Grant BD, Hemmer W, Tsigelny I, Adams JA, Taylor SS. Kinetic analyses of mutations in the glycine-rich loop of cAMP-dependent protein kinase. Biochemistry. 37: 7708-15. PMID 9601030 DOI: 10.1021/Bi972987W |
0.452 |
|
| 1998 |
Durick K, Gill GN, Taylor SS. Shc and enigma are both required for mitogenic signaling by Ret/ptc2 Molecular and Cellular Biology. 18: 2298-2308. PMID 9528800 DOI: 10.1128/Mcb.18.4.2298 |
0.472 |
|
| 1998 |
Shaltiel S, Cox S, Taylor SS. Conserved water molecules contribute to the extensive network of interactions at the active site of protein kinase A Proceedings of the National Academy of Sciences of the United States of America. 95: 484-491. PMID 9435218 DOI: 10.1073/Pnas.95.2.484 |
0.504 |
|
| 1998 |
Smith CM, Shindyalov IN, Veretnik S, Gribskov M, Taylor SS, Ten Eyck LF, Bourne PE. The protein kinase resource. Trends in Biochemical Sciences. 22: 444-6. PMID 9397688 DOI: 10.1016/S0968-0004(97)01131-6 |
0.47 |
|
| 1997 |
Taylor SS, Radzio-Andzelm E. Protein kinase inhibition: Natural and synthetic variations on a theme Current Opinion in Chemical Biology. 1: 219-226. PMID 9667861 DOI: 10.1016/S1367-5931(97)80013-0 |
0.527 |
|
| 1997 |
Yonemoto W, McGlone ML, Grant B, Taylor SS. Autophosphorylation of the catalytic subunit of cAMP-dependent protein kinase in Escherichia coli. Protein Engineering. 10: 915-25. PMID 9415441 DOI: 10.1093/Protein/10.8.915 |
0.532 |
|
| 1997 |
Gibson RM, Taylor SS. Dissecting the cooperative reassociation of the regulatory and catalytic subunits of cAMP-dependent protein kinase. Role of Trp-196 in the catalytic subunit Journal of Biological Chemistry. 272: 31998-32005. PMID 9405392 DOI: 10.1074/Jbc.272.51.31998 |
0.514 |
|
| 1997 |
León DA, Herberg FW, Banky P, Taylor SS. A stable alpha-helical domain at the N terminus of the RIalpha subunits of cAMP-dependent protein kinase is a novel dimerization/docking motif. The Journal of Biological Chemistry. 272: 28431-7. PMID 9353302 DOI: 10.1074/Jbc.272.45.28431 |
0.824 |
|
| 1997 |
Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS. D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain. Proceedings of the National Academy of Sciences of the United States of America. 94: 11184-9. PMID 9326583 DOI: 10.1073/Pnas.94.21.11184 |
0.49 |
|
| 1997 |
Gibson RM, Ji-Buechler Y, Taylor SS. Identification of electrostatic interaction sites between the regulatory and catalytic subunits of cyclic AMP-dependent protein kinase Protein Science. 6: 1825-1834. PMID 9300482 DOI: 10.1002/Pro.5560060903 |
0.504 |
|
| 1997 |
Narayana N, Cox S, Xuong NH, Ten Eyck LF, Taylor SS. A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility Structure. 5: 921-935. PMID 9261084 DOI: 10.1016/S0969-2126(97)00246-3 |
0.703 |
|
| 1997 |
Hemmer W, McGlone M, Tsigelny I, Taylor SS. Role of the glycine triad in the ATP-binding site of cAMP-dependent protein kinase. The Journal of Biological Chemistry. 272: 16946-54. PMID 9202006 DOI: 10.1074/Jbc.272.27.16946 |
0.559 |
|
| 1997 |
Gibson RM, Ji-Buechler Y, Taylor SS. Interaction of the regulatory and catalytic subunits of cAMP-dependent protein kinase: Electrostatic sites on the type Iα regulatory subunit Journal of Biological Chemistry. 272: 16343-16350. PMID 9195940 DOI: 10.1074/Jbc.272.26.16343 |
0.505 |
|
| 1997 |
Lew J, Taylor SS, Adams JA. Identification of a partially rate-determining step in the catalytic mechanism of cAMP-dependent protein kinase: a transient kinetic study using stopped-flow fluorescence spectroscopy. Biochemistry. 36: 6717-24. PMID 9184152 DOI: 10.1021/Bi963164U |
0.441 |
|
| 1997 |
Padilla A, Hauer JA, Tsigelny I, Parello J, Taylor SS. Solution structure of synthetic peptide inhibitor and substrate of cAMP-dependent protein kinase. A study by 2D H NMR and molecular dynamics. The Journal of Peptide Research : Official Journal of the American Peptide Society. 49: 210-20. PMID 9151254 DOI: 10.1111/J.1399-3011.1997.Tb00880.X |
0.49 |
|
| 1997 |
Narayana N, Cox S, Shaltiel S, Taylor SS, Xuong NH. Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of camp-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine Biochemistry. 36: 4438-4448. PMID 9109651 DOI: 10.1021/Bi961947+ |
0.685 |
|
| 1997 |
Herberg FW, Zimmermann B, McGlone M, Taylor SS. Importance of the A-helix of the catalytic subunit of cAMP-dependent protein kinase for stability and for orienting subdomains at the cleft interface. Protein Science : a Publication of the Protein Society. 6: 569-79. PMID 9070439 DOI: 10.1002/Pro.5560060306 |
0.563 |
|
| 1997 |
Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS. Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits. The Journal of Biological Chemistry. 272: 8057-64. PMID 9065479 DOI: 10.1074/Jbc.272.12.8057 |
0.5 |
|
| 1997 |
Hemmer W, McGlone M, Taylor SS. Recombinant strategies for rapid purification of catalytic subunits of cAMP-dependent protein kinase Analytical Biochemistry. 245: 115-122. PMID 9056191 DOI: 10.1006/Abio.1996.9952 |
0.509 |
|
| 1997 |
Lew J, Coruh N, Tsigelny I, Garrod S, Taylor SS. Synergistic binding of nucleotides and inhibitors to cAMP-dependent protein kinase examined by acrylodan fluorescence spectroscopy Journal of Biological Chemistry. 272: 1507-1513. PMID 8999821 DOI: 10.1074/Jbc.272.3.1507 |
0.495 |
|
| 1996 |
Grant BD, Tsigelny I, Adams JA, Taylor SS. Examination of an active-site electrostatic node in the cAMP-dependent protein kinase catalytic subunit. Protein Science : a Publication of the Protein Society. 5: 1316-24. PMID 8819164 DOI: 10.1002/Pro.5560050710 |
0.54 |
|
| 1996 |
Tsigelny I, Grant BD, Taylor SS, Ten Eyck LF. Catalytic subunit of cAMP-dependent protein kinase: Electrostatic features and peptide recognition Biopolymers. 39: 353-365. PMID 8756515 DOI: 10.1002/(Sici)1097-0282(199609)39:3<353::Aid-Bip7>3.0.Co;2-N |
0.491 |
|
| 1996 |
Wu R, Durick K, Songyang Z, Cantley LC, Taylor SS, Gill GN. Specificity of LIM domain interactions with receptor tyrosine kinases. The Journal of Biological Chemistry. 271: 15934-41. PMID 8663233 DOI: 10.1074/Jbc.271.27.15934 |
0.459 |
|
| 1996 |
Durick K, Wu RY, Gill GN, Taylor SS. Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain. The Journal of Biological Chemistry. 271: 12691-4. PMID 8662982 DOI: 10.1074/Jbc.271.22.12691 |
0.531 |
|
| 1996 |
Chestukhin A, Litovchick L, Schourov D, Cox S, Taylor SS, Shaltiel S. Functional malleability of the carboxyl-terminal tail in protein kinase A. The Journal of Biological Chemistry. 271: 10175-82. PMID 8626579 DOI: 10.1074/Jbc.271.17.10175 |
0.55 |
|
| 1996 |
Herberg FW, Taylor SS, Dostmann WRG. Active site mutations define the pathway for the cooperative activation of cAMP-dependent protein kinase Biochemistry. 35: 2934-2942. PMID 8608131 DOI: 10.1021/Bi951647C |
0.445 |
|
| 1995 |
Koide K, Bunnage ME, Gomez Paloma L, Kanter JR, Taylor SS, Brunton LL, Nicolaou KC. Molecular design and biological activity of potent and selective protein kinase inhibitors related to balanol. Chemistry & Biology. 2: 601-8. PMID 9383464 DOI: 10.1016/1074-5521(95)90124-8 |
0.475 |
|
| 1995 |
Andzelm ER, Lew J, Taylor S. Bound to activate: conformational consequences of cyclin binding to CDK2 Structure. 3: 1135-1141. PMID 8591024 DOI: 10.1016/S0969-2126(01)00249-0 |
0.463 |
|
| 1995 |
Cox S, Taylor SS. Kinetic analysis of cAMP-dependent protein kinase: Mutations at histidine 87 affect peptide binding and pH dependence Biochemistry. 34: 16203-16209. PMID 8519778 DOI: 10.1021/Bi00049A036 |
0.438 |
|
| 1995 |
Adams JA, McGlone ML, Gibson R, Taylor SS. Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase. Biochemistry. 34: 2447-54. PMID 7873523 DOI: 10.1021/Bi00008A007 |
0.553 |
|
| 1995 |
Armstrong R, Wen W, Meinkoth J, Taylor S, Montminy M. A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A. Molecular and Cellular Biology. 15: 1826-32. PMID 7862172 DOI: 10.1128/Mcb.15.3.1826 |
0.423 |
|
| 1995 |
Wen W, Taylor SS, Meinkoth JL. The expression and intracellular distribution of the heat-stable protein kinase inhibitor is cell cycle regulated Journal of Biological Chemistry. 270: 2041-2046. PMID 7836431 DOI: 10.1074/Jbc.270.5.2041 |
0.373 |
|
| 1995 |
Su Y, Dostmann WR, Herberg FW, Durick K, Xuong NH, Ten Eyck L, Taylor SS, Varughese KI. Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains. Science (New York, N.Y.). 269: 807-13. PMID 7638597 DOI: 10.1126/Science.7638597 |
0.552 |
|
| 1995 |
Wen W, Meinkotht JL, Tsien RY, Taylor SS. Identification of a signal for rapid export of proteins from the nucleus Cell. 82: 463-473. PMID 7634336 DOI: 10.1016/0092-8674(95)90435-2 |
0.441 |
|
| 1995 |
Durick K, Yao VJ, Borrello MG, Bongarzone I, Pierotti MA, Taylor SS. Tyrosines outside the kinase core and dimerization are required for the mitogenic activity of RET/ptc2. The Journal of Biological Chemistry. 270: 24642-5. PMID 7559572 DOI: 10.1074/Jbc.270.42.24642 |
0.5 |
|
| 1995 |
Taylor SS, Radzio-Andzelm E, Hunter T. How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein-tyrosine kinase Faseb Journal. 9: 1255-1266. PMID 7557015 DOI: 10.1096/Fasebj.9.13.7557015 |
0.541 |
|
| 1994 |
Taylor SS, Radzio-Andzelm E. Three protein kinase structures define a common motif Structure. 2: 345-355. PMID 8081750 DOI: 10.1016/S0969-2126(00)00036-8 |
0.519 |
|
| 1994 |
Madhusudan, Trafny EA, Xuong NH, Adams JA, Ten Eyck LF, Taylor SS, Sowadski JM. cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer. Protein Science : a Publication of the Protein Society. 3: 176-87. PMID 8003955 DOI: 10.1002/Pro.5560030203 |
0.664 |
|
| 1994 |
Herberg FW, Dostmann WR, Zorn M, Davis SJ, Taylor SS. Crosstalk between domains in the regulatory subunit of cAMP-dependent protein kinase: influence of amino terminus on cAMP binding and holoenzyme formation. Biochemistry. 33: 7485-94. PMID 8003514 DOI: 10.1021/Bi00189A057 |
0.525 |
|
| 1994 |
Solberg R, Taskén K, Wen W, Coghlan VM, Meinkoth JL, Scott JD, Jahnsen T, Taylor SS. Human regulatory subunit RI beta of cAMP-dependent protein kinases: expression, holoenzyme formation and microinjection into living cells. Experimental Cell Research. 214: 595-605. PMID 7925653 DOI: 10.1006/Excr.1994.1297 |
0.367 |
|
| 1994 |
Cox S, Radzio-Andzelm E, Taylor SS. Domain movements in protein kinases Current Opinion in Structural Biology. 4: 893-901. PMID 7712293 DOI: 10.1016/0959-440X(94)90272-0 |
0.552 |
|
| 1993 |
Taylor SS, Knighton DR, Zheng J, Sowadski JM, Gibbs CS, Zoller MJ. A template for the protein kinase family. Trends in Biochemical Sciences. 18: 84-9. PMID 8480367 DOI: 10.1016/0968-0004(93)80001-R |
0.53 |
|
| 1993 |
Su Y, Taylor SS, Dostmann WRG, Xuong NH, Varughese KI. Crystallization of a deletion mutant of the R-subunit of cAMP dependent protein kinase Journal of Molecular Biology. 230: 1091-1093. PMID 8478923 DOI: 10.1006/Jmbi.1993.1224 |
0.634 |
|
| 1993 |
Zheng J, Knighton DR, ten Eyck LF, Karlsson R, Xuong N, Taylor SS, Sowadski JM. Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor. Biochemistry. 32: 2154-61. PMID 8443157 DOI: 10.1021/Bi00060A005 |
0.701 |
|
| 1993 |
Knighton DR, Cadena DL, Zheng J, Ten Eyck LF, Taylor SS, Sowadski JM, Gill GN. Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 5001-5. PMID 8389462 DOI: 10.1073/Pnas.90.11.5001 |
0.536 |
|
| 1993 |
Marcote MJ, Knighton DR, Basi G, Sowadski JM, Brambilla P, Draetta G, Taylor SS. A three-dimensional model of the Cdc2 protein kinase: localization of cyclin- and Suc1-binding regions and phosphorylation sites. Molecular and Cellular Biology. 13: 5122-31. PMID 8336738 DOI: 10.1128/Mcb.13.8.5122 |
0.492 |
|
| 1993 |
Adams JA, Taylor SS. Divalent metal ions influence catalysis and active-site accessibility in the cAMP-dependent protein kinase. Protein Science : a Publication of the Protein Society. 2: 2177-86. PMID 8298463 DOI: 10.1002/Pro.5560021217 |
0.413 |
|
| 1993 |
Harootunian AT, Adams SR, Wen W, Meinkoth JL, Taylor SS, Tsien RY. Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusion Molecular Biology of the Cell. 4: 993-1002. PMID 8298196 DOI: 10.1091/Mbc.4.10.993 |
0.429 |
|
| 1993 |
Herberg FW, Taylor SS. Physiological inhibitors of the catalytic subunit of cAMP-dependent protein kinase: Effect of MgATP on protein-protein interactions Biochemistry. 32: 14015-14022. PMID 8268180 DOI: 10.1021/Bi00213A035 |
0.487 |
|
| 1993 |
Zheng J, Knighton DR, Xuong NH, Taylor SS, Sowadski JM, Eyck LFT. Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations Protein Science. 2: 1559-1573. PMID 8251932 DOI: 10.1002/Pro.5560021003 |
0.695 |
|
| 1993 |
Herberg FW, Bell SM, Taylor SS. Expression of the catalytic subunit of camp-dependent protein kinase in Escherichia coli: Multiple isozymes reflect different phosphorylation states Protein Engineering, Design and Selection. 6: 771-777. PMID 8248101 DOI: 10.1093/Protein/6.7.771 |
0.504 |
|
| 1993 |
Taylor SS, Zheng J, Radzio-Andzelm E, Knighton DR, Ten Eyck LF, Sowadski JM, Herberg FW, Yonemoto WM. cAMP-dependent protein kinase defines a family of enzymes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 340: 315-24. PMID 8103934 DOI: 10.1098/Rstb.1993.0073 |
0.571 |
|
| 1993 |
Meinkoth JL, Alberts AS, Went W, Fantozzi D, Taylor SS, Hagiwara M, Montminy M, Feramisco JR. Signal transduction through the cAMP-dependent protein kinase. Molecular and Cellular Biochemistry. 127: 179-86. PMID 7935349 DOI: 10.1007/Bf01076769 |
0.459 |
|
| 1993 |
Veron M, Radzio-Andzelm E, Tsigelny I, Ten Eyck LF, Taylor SS. A conserved helix motif complements the protein kinase core. Proceedings of the National Academy of Sciences of the United States of America. 90: 10618-22. PMID 7504272 DOI: 10.1073/Pnas.90.22.10618 |
0.569 |
|
| 1993 |
Taylor SS, Knighton DR, Zheng J, Ten Eyck LF, Sowadski JM. Structural framework for the protein kinase family. Annual Review of Cell Biology. 8: 429-62. PMID 1335745 DOI: 10.1146/Annurev.Cb.08.110192.002241 |
0.562 |
|
| 1993 |
Taylor SS, Knighton DR, Zheng J, Ten Eyck LF, Sowadski JM. cAMP-dependent protein kinase and the protein kinase family. Faraday Discussions. 143-52. PMID 1290929 DOI: 10.1039/Fd9929300143 |
0.568 |
|
| 1992 |
Zheng JH, Knighton DR, Xuong NH, Parello J, Taylor SS, Sowadski JM. Crystallization studies of the catalytic subunit of cAMP-dependent protein kinase: crystals of murine recombinant catalytic subunit and a mutant, Cys 343----Ser, diffract to 2.7 A resolution Acta Crystallographica. Section B, Structural Science. 48. PMID 1515113 DOI: 10.1107/S0108768192000909 |
0.64 |
|
| 1992 |
Knighton DR, Pearson RB, Sowadski JM, Means AR, Ten Eyck LF, Taylor SS, Kemp BE. Structural basis of the intrasteric regulation of myosin light chain kinases. Science (New York, N.Y.). 258: 130-5. PMID 1439761 DOI: 10.1126/Science.1439761 |
0.493 |
|
| 1992 |
Adams JA, Taylor SS. Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments. Biochemistry. 31: 8516-22. PMID 1390637 DOI: 10.1021/Bi00151A019 |
0.46 |
|
| 1992 |
Mann SKO, Yonemoto WM, Taylor SS, Firtel RA. DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase Proceedings of the National Academy of Sciences of the United States of America. 89: 10701-10705. PMID 1332055 DOI: 10.1073/Pnas.89.22.10701 |
0.52 |
|
| 1992 |
Taylor SS, Adams JA. Protein kinases: coming of age Current Opinion in Structural Biology. 2: 743-748. DOI: 10.1016/0959-440X(92)90210-X |
0.55 |
|
| 1991 |
Zoller MJ, Yonemoto W, Taylor SS, Johnson KE. Mammalian cAMP-dependent protein kinase functionally replaces its homolog in yeast Gene. 99: 171-179. PMID 2022331 DOI: 10.1016/0378-1119(91)90124-T |
0.473 |
|
| 1991 |
Yonemoto WM, McGlone ML, Slice LW, Taylor SS. Prokaryotic expression of catalytic subunit of adenosine cyclic monophosphate-dependent protein kinase. Methods in Enzymology. 200: 581-96. PMID 1956337 DOI: 10.1016/0076-6879(91)00173-T |
0.52 |
|
| 1991 |
Zheng JH, Knighton DR, Parello J, Taylor SS, Sowadski JM. Crystallization of catalytic subunit of adenosine cyclic monophosphate-dependent protein kinase. Methods in Enzymology. 200: 508-21. PMID 1956335 DOI: 10.1016/0076-6879(91)00167-U |
0.399 |
|
| 1991 |
Buechler JA, Toner-Webb JA, Taylor SS. Carbodiimides as probes for protein kinase structure and function Methods in Enzymology. 200: 487-500. PMID 1956333 DOI: 10.1016/0076-6879(91)00165-S |
0.558 |
|
| 1991 |
Knighton DR, Zheng J, Ten Eyck LF, Xuong N, Taylor SS, Sowadski JM. Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase Science. 253: 414-420. PMID 1862343 DOI: 10.1126/Science.1862343 |
0.679 |
|
| 1991 |
Knighton DR, Zheng JH, Ten Eyck LF, Ashford VA, Xuong NH, Taylor SS, Sowadski JM. Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science (New York, N.Y.). 253: 407-14. PMID 1862342 DOI: 10.1126/Science.1862342 |
0.544 |
|
| 1991 |
Knighton DR, Xuong NH, Taylor SS, Sowadski JM. Crystallization studies of cAMP-dependent protein kinase. Cocrystals of the catalytic subunit with a 20 amino acid residue peptide inhibitor and MgATP diffract to 3.0 Å resolution Journal of Molecular Biology. 220: 217-220. PMID 1856856 DOI: 10.1016/0022-2836(91)90005-Q |
0.62 |
|
| 1991 |
León DA, Dostmann WR, Taylor SS. Unfolding of the regulatory subunit of cAMP-dependent protein kinase I. Biochemistry. 30: 3035-40. PMID 1848784 DOI: 10.1021/Bi00226A008 |
0.465 |
|
| 1991 |
Adams SR, Harootunian AT, Buechler YJ, Taylor SS, Tsien RY. Fluorescence ratio imaging of cyclic AMP in single cells Nature. 349: 694-697. PMID 1847505 DOI: 10.1038/349694A0 |
0.353 |
|
| 1991 |
Neitzel JJ, Dostmann WR, Taylor SS. Role of MgATP in the activation and reassociation of cAMP-dependent protein kinase I: consequences of replacing the essential arginine in cAMP binding site A. Biochemistry. 30: 733-9. PMID 1846304 DOI: 10.1021/Bi00217A023 |
0.502 |
|
| 1991 |
Dostmann WR, Taylor SS. Identifying the molecular switches that determine whether (Rp)-cAMPS functions as an antagonist or an agonist in the activation of cAMP-dependent protein kinase I. Biochemistry. 30: 8710-6. PMID 1653606 DOI: 10.1021/Bi00099A032 |
0.538 |
|
| 1990 |
Duronio RJ, Jackson-Machelski E, Heuckeroth RO, Olins PO, Devine CS, Yonemoto W, Slice LW, Taylor SS, Gordon JI. Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria. Proceedings of the National Academy of Sciences of the United States of America. 87: 1506-10. PMID 2406721 DOI: 10.1073/Pnas.87.4.1506 |
0.34 |
|
| 1990 |
Meinkoth JL, Ji Y, Taylor SS, Feramisco JR. Dynamics of the distribution of cyclic AMP-dependent protein kinase in living cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 9595-9. PMID 2263615 DOI: 10.1073/Pnas.87.24.9595 |
0.497 |
|
| 1990 |
Taylor SS, Buechler JA, Yonemoto W. cAMP-dependent protein kinase: Framework for a diverse family of regulatory enzymes Annual Review of Biochemistry. 59: 971-1105. PMID 2165385 DOI: 10.1146/Annurev.Bi.59.070190.004543 |
0.559 |
|
| 1989 |
First EA, Johnson DA, Taylor SS. Fluorescence energy transfer between cysteine 199 and cysteine 343: evidence for MgATP-dependent conformational change in the catalytic subunit of cAMP-dependent protein kinase. Biochemistry. 28: 3606-13. PMID 2787168 DOI: 10.1021/Bi00434A068 |
0.432 |
|
| 1989 |
First EA, Taylor SS. Selective modification of the catalytic subunit of cAMP-dependent protein kinase with sulfhydryl-specific fluorescent probes Biochemistry. 28: 3598-3605. PMID 2742857 DOI: 10.1021/Bi00434A067 |
0.445 |
|
| 1989 |
Taylor SS. cAMP-dependent protein kinase. Model for an enzyme family Journal of Biological Chemistry. 264: 8443-8446. PMID 2656679 DOI: 10.1016/B978-012124546-7/50560-X |
0.334 |
|
| 1989 |
Buechler JA, Vedvick TA, Taylor SS. Differential labeling of the catalytic subunit of cAMP-dependent protein kinase with acetic anhydride: Substrate-induced conformational changes Biochemistry. 28: 3018-3024. PMID 2500968 DOI: 10.1021/Bi00433A042 |
0.502 |
|
| 1989 |
Buechler JA, Taylor SS. Dicyclohexylcarbodiimide cross-links two conserved residues, Asp-184 and Lys-72, at the active site of the catalytic subunit of cAMP-dependent protein kinase Biochemistry. 28: 2065-2070. PMID 2497773 DOI: 10.1021/Bi00431A015 |
0.455 |
|
| 1988 |
First EA, Bubis J, Taylor SS. Subunit interaction sites between the regulatory and catalytic subunits of cAMP-dependent protein kinase. Identification of a specific interchain disulfide bond. The Journal of Biological Chemistry. 263: 5176-82. PMID 3356685 |
0.631 |
|
| 1988 |
Taylor SS, Bubis J, Toner-Webb J, Saraswat LD, First EA, Buechler JA, Knighton DR, Sowadski J. CAMP-dependent protein kinase: prototype for a family of enzymes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 2677-85. PMID 3294077 DOI: 10.1096/Fasebj.2.11.3294077 |
0.74 |
|
| 1988 |
Taylor SS, Buechler JA, Slice LW, Knighton DK, Durgerian S, Ringheim GE, Neitzel JJ, Yonemoto WM, Sowadski JM, Dospmann W. cAMP-dependent protein kinase: A framework for a diverse family of enzymes Cold Spring Harbor Symposia On Quantitative Biology. 53: 121-130. PMID 3076077 DOI: 10.1101/Sqb.1988.053.01.018 |
0.451 |
|
| 1988 |
Saraswat LD, Filutowics M, Taylor S. Expression and mutagenesis of the regulatory subunit of cAMP-dependent protein kinase in Escherichia coli. Methods in Enzymology. 159: 325-36. PMID 3045499 DOI: 10.1016/0076-6879(88)59033-X |
0.414 |
|
| 1988 |
Buechler JA, Taylor SS. Identification of aspartate-184 as an essential residue in the catalytic subunit of cAMP-dependent protein kinase Biochemistry. 27: 7356-7361. PMID 2905166 DOI: 10.1021/Bi00419A027 |
0.474 |
|
| 1988 |
Bubis J, Neitzel JJ, Saraswat LD, Taylor SS. A point mutation abolishes binding of cAMP to site A in the regulatory subunit of cAMP-dependent protein kinase. The Journal of Biological Chemistry. 263: 9668-73. PMID 2898473 |
0.653 |
|
| 1988 |
Ringheim GE, Saraswat LD, Bubis J, Taylor SS. Deletion of cAMP-binding site B in the regulatory subunit of cAMP-dependent protein kinase alters the photoaffinity labeling of site A. The Journal of Biological Chemistry. 263: 18247-52. PMID 2848031 |
0.65 |
|
| 1988 |
Saraswat LD, Ringheim GE, Bubis J, Taylor SS. Deletion mutants as probes for localizing regions of subunit interaction in cAMP-dependent protein kinase. The Journal of Biological Chemistry. 263: 18241-6. PMID 2848030 |
0.697 |
|
| 1988 |
Bubis J, Saraswat LD, Taylor SS. Tyrosine-371 contributes to the positive cooperativity between the two cAMP binding sites in the regulatory subunit of cAMP-dependent protein kinase I. Biochemistry. 27: 1570-6. PMID 2835094 DOI: 10.1021/Bi00405A026 |
0.707 |
|
| 1988 |
Taylor SS, Bubis J, Sowadski J, Toner JA, Saraswat LD. Relation Between Structure and Function in cAMP-Dependent Protein Kinases Annals of the New York Academy of Sciences. 478: 327-341. DOI: 10.1007/978-1-4612-3744-0_38 |
0.74 |
|
| 1987 |
Bubis J, Taylor SS. Limited proteolysis alters the photoaffinity labeling of adenosine 3',5'-monophosphate dependent protein kinase II with 8-azidoadenosine 3',5'-monophosphate. Biochemistry. 26: 5997-6004. PMID 3689756 DOI: 10.1021/Bi00393A008 |
0.685 |
|
| 1987 |
Bubis J, Vedvick TS, Taylor SS. Antiparallel alignment of the two protomers of the regulatory subunit dimer of cAMP-dependent protein kinase I. The Journal of Biological Chemistry. 262: 14961-6. PMID 3667618 |
0.658 |
|
| 1987 |
Toner-Webb J, Taylor SS. Inhibition of the catalytic subunit of cAMP-dependent protein kinase by dicyclohexylcarbodiimide Biochemistry. 26: 7371-7378. PMID 3501317 DOI: 10.1021/Bi00397A026 |
0.474 |
|
| 1987 |
Weber IT, Steitz TA, Bubis J, Taylor SS. Predicted structures of cAMP binding domains of type I and II regulatory subunits of cAMP-dependent protein kinase. Biochemistry. 26: 343-51. PMID 3030405 DOI: 10.1021/Bi00376A003 |
0.717 |
|
| 1987 |
Bubis J, Taylor SS. Correlation of photolabeling with occupancy of cAMP binding sites in the regulatory subunit of cAMP-dependent protein kinase I. Biochemistry. 26: 3478-86. PMID 2820470 DOI: 10.1021/Bi00386A035 |
0.665 |
|
| 1987 |
Taylor SS. Protein kinases: A diverse family of related proteins Bioessays. 7: 24-29. PMID 2820389 DOI: 10.1002/Bies.950070106 |
0.524 |
|
| 1987 |
Taylor P, Schumacher M, MacPhee-Quigley K, Friedmann T, Taylor S. The structure of acetylcholinesterase: relationship to its function and cellular disposition Trends in Neurosciences. 10: 93-95. DOI: 10.1016/0166-2236(87)90033-6 |
0.356 |
|
| 1986 |
Schumacher M, Camp S, Maulet Y, Newton M, MacPhee-Quigley K, Taylor SS, Friedmann T, Taylor P. Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence. Nature. 319: 407-9. PMID 3753747 DOI: 10.1038/319407A0 |
0.361 |
|
| 1986 |
Taylor SS, Saraswat LD, Toner JA, Bubis J. The relationship between structure and function in cAMP-dependent protein kinases. Annals of the New York Academy of Sciences. 478: 191-202. PMID 3026223 DOI: 10.1111/J.1749-6632.1986.Tb15531.X |
0.681 |
|
| 1985 |
Sowadski JM, Xuong Nh, Anderson D, Taylor SS. Crystallization studies of cAMP-dependent protein kinase. Crystals of catalytic subunit diffract to 3.5 Å resolution Journal of Molecular Biology. 182: 617-620. PMID 4009717 DOI: 10.1016/0022-2836(85)90249-9 |
0.621 |
|
| 1985 |
Dothie JM, Giglio JR, Moore CB, Taylor SS, Hartley BS. Ribitol dehydrogenase of Klebsiella aerogenes. Sequence and properties of wild-type and mutant strains. The Biochemical Journal. 230: 569-78. PMID 3904726 DOI: 10.1042/Bj2300569 |
0.54 |
|
| 1985 |
Jurgensen SR, Chock PB, Taylor S, Vandenheede JR, Merlevede W. Inhibition of the Mg(II).ATP-dependent phosphoprotein phosphatase by the regulatory subunit of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 82: 7565-9. PMID 2999770 DOI: 10.1073/Pnas.82.22.7565 |
0.507 |
|
| 1985 |
Bubis J, Taylor SS. Covalent modification of both cAMP binding sites in cAMP-dependent protein kinase I by 8-azidoadenosine 3',5'-monophosphate. Biochemistry. 24: 2163-70. PMID 2986689 DOI: 10.1021/Bi00330A009 |
0.71 |
|
| 1985 |
Mumby MC, Weldon SL, Scott CW, Taylor SS. Monoclonal antibodies as probes of structure, function and isoenzyme forms of the type II regulatory subunit of cyclic AMP-dependent protein kinase. Pharmacology & Therapeutics. 28: 367-87. PMID 2418450 DOI: 10.1016/0163-7258(85)90059-2 |
0.395 |
|
| 1984 |
Kamps MP, Taylor SS, Sefton BM. Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites. Nature. 310: 589-92. PMID 6431300 DOI: 10.1038/310589A0 |
0.56 |
|
| 1984 |
Taylor SS, Kerlavage AR, Zoller MJ. Affinity labeling of cAMP-dependent protein kinases. Methods in Enzymology. 99: 140-53. PMID 6316084 DOI: 10.1016/0076-6879(83)99047-X |
0.464 |
|
| 1983 |
Siebenaller JF, Orr TL, Olwin BB, Taylor SS. Comparison of the D-lactate stereospecific dehydrogenase of Limulus polyphemus with active-site regions of L-lactate dehydrogenases. Biochimica Et Biophysica Acta. 749: 153-62. PMID 6652095 DOI: 10.1016/0167-4838(83)90247-9 |
0.322 |
|
| 1983 |
Doctor BP, Camp S, Gentry MK, Taylor SS, Taylor P. Antigenic and structural differences in the catalytic subunits of the molecular forms of acetylcholinesterase. Proceedings of the National Academy of Sciences of the United States of America. 80: 5767-71. PMID 6193524 DOI: 10.1073/Pnas.80.18.5767 |
0.322 |
|
| 1978 |
Potter RL, Stafford PH, Taylor S. Regulatory subunit of cyclic AMP-dependent protein kinase I from porcine skeletal muscle: purification and proteolysis. Archives of Biochemistry and Biophysics. 190: 174-80. PMID 213029 DOI: 10.1016/0003-9861(78)90265-5 |
0.438 |
|
| 1978 |
Taylor SS, Dixon JE. Affinity chromatography of lactate dehydrogenase. A biochemistry experiment Journal of Chemical Education. 55: 675. DOI: 10.1021/Ed055P675 |
0.466 |
|
| 1976 |
Taylor SS, Oxley SS. Homologies in the active site regions of lactate dehydrogenases Archives of Biochemistry and Biophysics. 175: 373-383. PMID 962329 DOI: 10.1016/0003-9861(76)90524-5 |
0.351 |
|
| 1976 |
Taylor SS, Lee CY, Swain L, Stafford PH. Cyclic AMP-dependent protein kinase: Purification of the holoenzyme by affinity chromatography Analytical Biochemistry. 76: 45-52. PMID 187080 DOI: 10.1016/0003-2697(76)90262-1 |
0.455 |
|
| 1975 |
Taylor SS, Allison WS, Kaplan NO. The amino acid sequence of the tryptic peptides isolated from dogfish M4 lactate dehydrogenase. The Journal of Biological Chemistry. 250: 8740-7. PMID 1184589 |
0.62 |
|
| 1974 |
Taylor SS, Rigby PW, Hartley BS. Ribitol dehydrogenase from Klebsiella aerogenes. Purification and subunit structure. The Biochemical Journal. 141: 693-700. PMID 4618776 DOI: 10.1042/Bj1410693 |
0.566 |
|
| 1974 |
Kaplan NO, Everse J, Dixon JE, Stolzenbach FE, Lee CY, Lee CL, Taylor SS, Mosbach K. Purification and separation of pyridine nucleotide-linked dehydrogenases by affinity chromatography techniques. Proceedings of the National Academy of Sciences of the United States of America. 71: 3450-4. PMID 4372619 DOI: 10.1073/Pnas.71.9.3450 |
0.618 |
|
| 1973 |
Taylor SS, Oxley SS, Allison WS, Kaplan NO. Aminoacid sequence of dogfish M4 lactate dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America. 70: 1790-3. PMID 4515938 DOI: 10.1073/Pnas.70.6.1790 |
0.658 |
|
| 1973 |
Adams MJ, Buehner M, Chandrasekhar K, Ford GC, Hackert ML, Liljas A, Rossmann MG, Smiley IE, Allison WS, Everse J, Kaplan NO, Taylor SS. Structure-function relationships in lactate dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America. 70: 1968-72. PMID 4146647 DOI: 10.1073/Pnas.70.7.1968 |
0.717 |
|
| 1969 |
Taylor SS, Heath EC. The incorporation of beta-hydroxy fatty acids into a phospholipid of Escherichia coli B. The Journal of Biological Chemistry. 244: 6605-16. PMID 4902888 |
0.519 |
|
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