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Alexey E. Granovsky, Ph.D. - Publications

Affiliations: 
2002 University of Iowa, Iowa City, IA 
Area:
Molecular Biology, Biochemistry
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Shemon AN, Heil GL, Granovsky AE, Clark MM, McElheny D, Chimon A, Rosner MR, Koide S. Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands. Plos One. 5: e10479. PMID 20463977 DOI: 10.1371/Journal.Pone.0010479  0.337
2009 Granovsky AE, Clark MC, McElheny D, Heil G, Hong J, Liu X, Kim Y, Joachimiak G, Joachimiak A, Koide S, Rosner MR. Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism. Molecular and Cellular Biology. 29: 1306-20. PMID 19103740 DOI: 10.1128/Mcb.01271-08  0.312
2003 Muradov KG, Granovsky AE, Artemyev NO. Mutation in rod PDE6 linked to congenital stationary night blindness impairs the enzyme inhibition by its gamma-subunit. Biochemistry. 42: 3305-10. PMID 12641462 DOI: 10.1021/Bi027095X  0.672
2002 Muradov KG, Granovsky AE, Schey KL, Artemyev NO. Direct interaction of the inhibitory gamma-subunit of Rod cGMP phosphodiesterase (PDE6) with the PDE6 GAFa domains. Biochemistry. 41: 3884-90. PMID 11900530 DOI: 10.1021/Bi015935M  0.699
2002 Granovsky AE, Artemyev NO. Assays of G protein/cGMP-phosphodiesterase interactions. Methods in Enzymology. 345: 27-37. PMID 11665611 DOI: 10.1016/S0076-6879(02)45004-5  0.641
2001 Granovsky AE, Artemyev NO. A conformational switch in the inhibitory gamma-subunit of PDE6 upon enzyme activation by transducin. Biochemistry. 40: 13209-15. PMID 11683629 DOI: 10.1021/Bi011127J  0.728
2001 Granovsky AE, Artemyev NO. Partial reconstitution of photoreceptor cGMP phosphodiesterase characteristics in cGMP phosphodiesterase-5. The Journal of Biological Chemistry. 276: 21698-703. PMID 11285263 DOI: 10.1074/Jbc.M100626200  0.732
2000 Granovsky AE, Artemyev NO. Identification of the gamma subunit-interacting residues on photoreceptor cGMP phosphodiesterase, PDE6alpha '. The Journal of Biological Chemistry. 275: 41258-62. PMID 11024033 DOI: 10.1074/Jbc.M008094200  0.745
2000 Granovsky AE, Muradov KG, Artemyev NO. Inhibition of photoreceptor cGMP phosphodiesterase by its gamma subunit. Methods in Enzymology. 315: 635-46. PMID 10736731 DOI: 10.1016/S0076-6879(00)15872-0  0.637
1999 Natochin M, Granovsky AE, Muradov KG, Artemyev NO. Roles of the transducin alpha-subunit alpha4-helix/alpha4-beta6 loop in the receptor and effector interactions. The Journal of Biological Chemistry. 274: 7865-9. PMID 10075679 DOI: 10.1074/Jbc.274.12.7865  0.644
1999 D'Amours MR, Granovsky AE, Artemyev NO, Cote RH. Potency and mechanism of action of E4021, a type 5 phosphodiesterase isozyme-selective inhibitor, on the photoreceptor phosphodiesterase depend on the state of activation of the enzyme. Molecular Pharmacology. 55: 508-14. PMID 10051534  0.67
1998 Granovsky AE, Natochin M, McEntaffer RL, Haik TL, Francis SH, Corbin JD, Artemyev NO. Probing domain functions of chimeric PDE6alpha'/PDE5 cGMP-phosphodiesterase. The Journal of Biological Chemistry. 273: 24485-90. PMID 9733741 DOI: 10.1074/Jbc.273.38.24485  0.696
1998 Natochin M, Granovsky AE, Artemyev NO. Identification of effector residues on photoreceptor G protein, transducin. The Journal of Biological Chemistry. 273: 21808-15. PMID 9705319 DOI: 10.1074/Jbc.273.34.21808  0.712
1998 Granovsky AE, McEntaffer R, Artemyev NO. Probing functional interfaces of rod PDE gamma-subunit using scanning fluorescent labeling. Cell Biochemistry and Biophysics. 28: 115-33. PMID 9515163 DOI: 10.1007/Bf02737808  0.63
1998 Granovsky AE, Artemyev NO. Chimeric Pα'/PDE5 cGMP-phosphodiesterase Faseb Journal. 12.  0.692
1997 Natochin M, Granovsky AE, Artemyev NO. Regulation of transducin GTPase activity by human retinal RGS. The Journal of Biological Chemistry. 272: 17444-9. PMID 9211888 DOI: 10.1074/Jbc.272.28.17444  0.681
1997 Granovsky AE, Natochin M, Artemyev NO. The gamma subunit of rod cGMP-phosphodiesterase blocks the enzyme catalytic site. The Journal of Biological Chemistry. 272: 11686-9. PMID 9115217 DOI: 10.1074/Jbc.272.18.11686  0.72
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