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Marsha Rich Rosner - Publications

Affiliations: 
Cancer Research University of Chicago, Chicago, IL 
Area:
Cell Biology, Molecular Biology, Oncology
Website:
https://benmay.uchicago.edu/faculty/rosner

148 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lee J, Olivieri C, Ong C, Masterson LR, Gomes S, Lee BS, Schaefer F, Lorenz K, Veglia G, Rosner MR. Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121867119. PMID 35696587 DOI: 10.1073/pnas.2121867119  0.362
2021 Rabe DC, Walker ND, Rustandy FD, Wallace J, Lee J, Stott SL, Rosner MR. Tumor Extracellular Vesicles Regulate Macrophage-Driven Metastasis through CCL5. Cancers. 13. PMID 34298673 DOI: 10.3390/cancers13143459  0.692
2020 Yesilkanal AE, Yang D, Tiwari P, Sabino AU, Lee J, Xie X, Sun S, Dann C, Steinberg E, Stuhlmiller T, Frankenberger C, Goldsmith E, Johnson GL, Ramos AF, Rosner M. Abstract 5038: Limited inhibition of multiple nodes in a driver network blocks metastasis Cancer Research. 80: 5038-5038. DOI: 10.1158/1538-7445.Am2020-5038  0.405
2020 Yang D, Dann C, Pott S, Rosner M. Abstract 2697: Single cell RNA sequencing and tumor cell heterogeneity in metastatic triple-negative breast cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2020-2697  0.368
2019 Tiwari P, Blank A, Cui C, Schoenfelt KQ, Zhou G, Xu Y, Khramtsova G, Olopade F, Shah AM, Khan SA, Rosner MR, Becker L. Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer. The Journal of Experimental Medicine. PMID 31053611 DOI: 10.1084/Jem.20181616  0.307
2019 Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, ... ... Rosner MR, et al. Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. Nature. PMID 30842661 DOI: 10.1038/S41586-019-1005-X  0.688
2019 Yang D, Pott S, Rosner M. Abstract 1128: Metastasis suppressor RKIP modulates gene expression variance in triple negative breast cancer Cancer Research. 79: 1128-1128. DOI: 10.1158/1538-7445.Am2019-1128  0.424
2018 Yesilkanal AE, Rosner MR. Targeting Raf Kinase Inhibitory Protein Regulation and Function. Cancers. 10. PMID 30181452 DOI: 10.3390/Cancers10090306  0.5
2018 Lee J, Yesilkanal A, Frankenberger C, Elbaz M, Rabe D, Yan J, Rustandy F, Hart P, Kang C, Grossman E, Locasale J, Nomura D, Bonini M, Rosner M. Abstract 5497: Effective combination therapy for breast cancer targeting BACH1 and mitochondrial metabolism Cancer Research. 78: 5497-5497. DOI: 10.1158/1538-7445.Am2018-5497  0.72
2018 Yesilkanal AE, Rabe DC, Tiwari P, Frankenberger C, Johnson GL, Rosner M. Abstract 4179: A novel approach for antimetastatic therapies against TNBC utilizing a physiologic suppressor Tumor Biology. DOI: 10.1158/1538-7445.Am2018-4179  0.638
2018 Rabe DC, Lee J, Rustandy F, Rosner MR. Abstract 1739: Tumor extracellular vesicles are required for tumor-associated macrophage programming Immunology. DOI: 10.1158/1538-7445.Am2018-1739  0.676
2017 Skinner JJ, Wang S, Lee J, Ong C, Sommese R, Sivaramakrishnan S, Koelmel W, Hirschbeck M, Schindelin H, Kisker C, Lorenz K, Sosnick TR, Rosner MR. Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome. Proceedings of the National Academy of Sciences of the United States of America. PMID 29208709 DOI: 10.1073/Pnas.1711543114  0.423
2017 Tiwari P, Schoenfelt K, Blank A, Cui C, Rosner MR, Becker L. Abstract 4229: Metabolically active macrophages: A novel link between obesity and TNBC Cancer Research. 77: 4229-4229. DOI: 10.1158/1538-7445.Am2017-4229  0.333
2017 Sosnick TR, Skinner JJ, Wang S, Lee J, Sommese R, Sivaramakrishnan S, Kölmel W, Hirschbeck M, Schindelin H, Kisker C, Lorenz K, Rosner MR. A Phospho-Induced Theft of a Salt Bridge in RKIP Links Map Kinase and G Protein-Mediated Signaling Biophysical Journal. 112: 63a-64a. DOI: 10.1016/J.Bpj.2016.11.382  0.42
2016 Bainer R, Frankenberger C, Rabe D, An G, Gilad Y, Rosner MR. Gene expression in local stroma reflects breast tumor states and predicts patient outcome. Scientific Reports. 6: 39240. PMID 27982086 DOI: 10.1038/Srep39240  0.705
2016 Wang X, Chow CR, Ebine K, Lee J, Rosner MR, Pan T, Munshi HG. Interaction of tRNA with MEK2 in pancreatic cancer cells. Scientific Reports. 6: 28260. PMID 27301426 DOI: 10.1038/Srep28260  0.384
2016 Lee J, Bainer R, Frankenberger C, Rabe D, Saleh s, Park M, An G, Gilad Y, Rosner MR. Abstract B15: Metastatic breast tumors regulate gene expression at distal mammary sites that predicts patient outcome Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-B15  0.717
2016 Yesilkanal AE, Frankenberger C, Rabe DC, Johnson GL, Rosner MR. Abstract 1620: Elucidating metastatic signaling networks in TNBC by investigating RKIP-regulated kinome Cancer Research. 76: 1620-1620. DOI: 10.1158/1538-7445.Tummet15-B23  0.777
2015 Frankenberger C, Rabe D, Bainer R, Sankarasharma D, Chada K, Krausz T, Gilad Y, Becker L, Rosner MR. Metastasis suppressors regulate the tumor microenvironment by blocking recruitment of pro-metastatic tumor-associated macrophages. Cancer Research. PMID 26238785 DOI: 10.1158/0008-5472.Can-14-3394  0.733
2015 Rabe DC, Frankenberger CA, Bainer R, Sankarasharma D, Chada K, Krausz T, Gilad Y, Rosner MR. Abstract B35: The role of tumor associated macrophages (TAMs) in triple-negative breast cancer (TNBC) invasion revealed by species-specific RNA sequencing Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-B35  0.726
2015 Frankenberger CA, Bainer RO, Rabe DC, Saleh S, Park M, Gilad Y, Rosner MR. Abstract A43: Systemic tumor-stroma interactions are prognostic indicators of breast tumor invasiveness Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-A43  0.715
2015 Rabe DC, Frankenberger C, Bainer R, Sankarasharma D, Chada K, Krausz T, Gilad Y, Becker L, Rosner MR. Abstract 1557: Metastasis suppressors regulate the tumor microenvironment by blocking recruitment of prometastatic TAMs Cancer Research. 76: 1557-1557. DOI: 10.1158/1538-7445.Am2016-1557  0.741
2015 Yesilkanal AE, Frankenberger C, Rabe D, Johnson GL, Rosner MR. Abstract 3251: Regulation of TNBC kinome by the metastasis suppressor Raf kinase inhibitory protein (RKIP) Cancer Research. 75: 3251-3251. DOI: 10.1158/1538-7445.Am2015-3251  0.767
2015 Tiwari P, Schoenfelt K, Kulkarni S, Rosner M, Becker L. Abstract 2888: Metabolically activated macrophages in obesity associated TNBC Cancer Research. 75: 2888-2888. DOI: 10.1158/1538-7445.Am2015-2888  0.307
2014 Skinner JJ, Rosner MR. RKIP structure drives its function: a three-state model for regulation of RKIP. Critical Reviews in Oncogenesis. 19: 483-8. PMID 25597357 DOI: 10.1615/Critrevoncog.2014012001  0.354
2014 Yesilkanal AE, Rosner MR. Raf kinase inhibitory protein (RKIP) as a metastasis suppressor: regulation of signaling networks in cancer. Critical Reviews in Oncogenesis. 19: 447-54. PMID 25597354 DOI: 10.1615/Critrevoncog.2014012000  0.446
2014 Lee J, Lee J, Farquhar KS, Yun J, Frankenberger CA, Bevilacqua E, Yeung K, Kim EJ, Balázsi G, Rosner MR. Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions. Proceedings of the National Academy of Sciences of the United States of America. 111: E364-73. PMID 24395801 DOI: 10.1073/Pnas.1304840111  0.415
2014 Sun M, Gomes S, Chen P, Frankenberger CA, Sankarasharma D, Chung CH, Chada KK, Rosner MR. RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2. Oncogene. 33: 3528-37. PMID 23975428 DOI: 10.1038/Onc.2013.328  0.456
2014 Yesilkanal AE, Rosner MR. Raf Kinase inhibitory protein (RKIP) as a metastasis suppressor: Regulation of signaling networks in cancer Critical Reviews in Oncogenesis. 19: 447-454. DOI: 10.1615/CritRevOncog.2014012000  0.338
2014 Bainer R, Frankenberger C, Rabe D, Saleh S, Park M, Chada K, Gilad Y, Rosner M. Abstract LB-320: Systemic tumor-stroma interactions are prognostic indicators of breast tumor invasiveness Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2014-Lb-320  0.692
2014 Rabe DC, Frankenberger C, Bainer R, Gilad Y, Rosner MR. Abstract 1084: Triple-negative breast cancer displays a unique subset of macrophages dependent on CCL5 signaling Cancer Research. 74: 1084-1084. DOI: 10.1158/1538-7445.Am2014-1084  0.727
2013 Lee U, Frankenberger C, Yun J, Bevilacqua E, Caldas C, Chin SF, Rueda OM, Reinitz J, Rosner MR. A prognostic gene signature for metastasis-free survival of triple negative breast cancer patients. Plos One. 8: e82125. PMID 24349199 DOI: 10.1371/Journal.Pone.0082125  0.386
2013 Sun M, Song CX, Huang H, Frankenberger CA, Sankarasharma D, Gomes S, Chen P, Chen J, Chada KK, He C, Rosner MR. HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 110: 9920-5. PMID 23716660 DOI: 10.1073/Pnas.1305172110  0.411
2013 Martinho O, Pinto F, Granja S, Miranda-Gonçalves V, Moreira MA, Ribeiro LF, di Loreto C, Rosner MR, Longatto-Filho A, Reis RM. RKIP inhibition in cervical cancer is associated with higher tumor aggressive behavior and resistance to cisplatin therapy. Plos One. 8: e59104. PMID 23527098 DOI: 10.1371/Journal.Pone.0059104  0.383
2013 Pavon-Eternod M, Gomes S, Rosner MR, Pan T. Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells. Rna (New York, N.Y.). 19: 461-6. PMID 23431330 DOI: 10.1261/Rna.037507.112  0.378
2013 Zeng L, Ehrenreiter K, Menon J, Menard R, Kern F, Nakazawa Y, Bevilacqua E, Imamoto A, Baccarini M, Rosner MR. RKIP regulates MAP kinase signaling in cells with defective B-Raf activity. Cellular Signalling. 25: 1156-65. PMID 23416466 DOI: 10.1016/J.Cellsig.2013.02.005  0.47
2013 Frankenberger CA, Bainer RO, Menon J, Chavarria C, Michelini K, Melsted P, Gilad Y, Rosner MR. Abstract B25: Using species-specific RNAseq reveals stromal reprogramming in triple-negative breast cancer xenografts Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-B25  0.452
2013 Lee J, Yun J, Yeung K, Bevilacqua E, Balázsi G, Rosner MR. Abstract A39: BACH1 and RKIP participate in a bistable network that affects progression to metastasis in breast Cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A39  0.392
2012 Menon J, Doebele RC, Gomes S, Bevilacqua E, Reindl KM, Rosner MR. A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer. Plos One. 7: e49893. PMID 23166790 DOI: 10.1371/Journal.Pone.0049893  0.381
2012 Zhou DH, Lee J, Frankenberger C, Geslain R, Rosner M, Pan T. Anti-tumor effects of an engineered "killer" transfer RNA. Biochemical and Biophysical Research Communications. 427: 148-53. PMID 22989754 DOI: 10.1016/J.Bbrc.2012.09.028  0.431
2012 Minn AJ, Bevilacqua E, Yun J, Rosner MR. Identification of novel metastasis suppressor signaling pathways for breast cancer. Cell Cycle (Georgetown, Tex.). 11: 2452-7. PMID 22659842 DOI: 10.4161/Cc.20624  0.454
2012 Bevilacqua E, Frankenberger CA, Rosner MR. RKIP Suppresses Breast Cancer Metastasis to the Bone by Regulating Stroma-Associated Genes. International Journal of Breast Cancer. 2012: 124704. PMID 22482058 DOI: 10.1155/2012/124704  0.461
2012 Martinho O, Granja S, Jaraquemada T, Caeiro C, Miranda-Gonçalves V, Honavar M, Costa P, Damasceno M, Rosner MR, Lopes JM, Reis RM. Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas. Plos One. 7: e30769. PMID 22292035 DOI: 10.1371/Journal.Pone.0030769  0.442
2012 Siu KT, Rosner MR, Minella AC. An integrated view of cyclin E function and regulation. Cell Cycle (Georgetown, Tex.). 11: 57-64. PMID 22186781 DOI: 10.4161/Cc.11.1.18775  0.386
2012 Gundacker C, Scheinast M, Damjanovic L, Fuchs C, Rosner M, Hengstschläger M. Proliferation potential of human amniotic fluid stem cells differently responds to mercury and lead exposure Amino Acids. 43: 937-949. PMID 22101983 DOI: 10.1007/S00726-011-1154-1  0.312
2012 Rosner M, Schipany K, Hengstschläger M. P70 S6K1 nuclear localization depends on its mTOR-mediated phosphorylation at T389, but not on its kinase activity towards S6 Amino Acids. 42: 2251-2256. PMID 21710263 DOI: 10.1007/S00726-011-0965-4  0.447
2012 Lee J, Yun J, Yeung KC, Rosner MR. Abstract 3433: Molecular regulation of RKIP, a tumor metastasis suppressor in breast cancer Cancer Research. 72: 3433-3433. DOI: 10.1158/1538-7445.Am2012-3433  0.427
2012 Frankenberger CA, Yun J, Eves EM, Diehn M, Minn AJ, Rosner MR. Abstract 3329: A let-7 signaling pathway targets metastatic genes enriched in tumor initiating cells Cancer Research. 72: 3329-3329. DOI: 10.1158/1538-7445.Am2012-3329  0.443
2011 Yun J, Frankenberger CA, Kuo WL, Boelens MC, Eves EM, Cheng N, Liang H, Li WH, Ishwaran H, Minn AJ, Rosner MR. Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. The Embo Journal. 30: 4500-14. PMID 21873975 DOI: 10.1038/Emboj.2011.312  0.416
2011 Rosner M, Hengstschläger M. Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR. Oncogene. 30: 4509-4522. PMID 21602892 DOI: 10.1038/Onc.2011.165  0.362
2011 Liu J, Kuo WL, Seiwert TY, Lingen M, Ciaccio MF, Jones RB, Rosner MR, Cohen EE. Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin. Head & Neck. 33: 1774-82. PMID 21438065 DOI: 10.1002/Hed.21701  0.44
2011 Rosner M, Fuchs C, Dolznig H, Hengstschläger M. Different cytoplasmic/nuclear distribution of S6 protein phosphorylated at S240/244 and S235/236 Amino Acids. 40: 595-600. PMID 20625781 DOI: 10.1007/S00726-010-0684-2  0.366
2011 Menon J, Doebele RS, Rosner MR. Abstract 3467: A novel interplay between Rap1, Epac and PKA regulates induction of angiogenesis Cancer Research. 71: 3467-3467. DOI: 10.1158/1538-7445.Am2011-3467  0.478
2011 Choi E, Eves E, Menon J, Rosner M. The Role Of Raf-1 Kinase Inhibitory Protein (RKIP) In Colorectal Cancer Liver Metastasis Journal of Surgical Research. 165: 291. DOI: 10.1016/J.Jss.2010.11.387  0.382
2010 Kuo WL, Liu J, Mauceri H, Vokes EE, Weichselbaum R, Rosner MR, Cohen EE. Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context. Molecular Cancer Therapeutics. 9: 2814-24. PMID 20876745 DOI: 10.1158/1535-7163.Mct-10-0352  0.485
2010 Eves EM, Rosner MR. MAP kinase regulation of the mitotic spindle checkpoint. Methods in Molecular Biology (Clifton, N.J.). 661: 497-505. PMID 20812004 DOI: 10.1007/978-1-60761-795-2_31  0.45
2010 Rosner M, Hengstschläger M. Evidence for cell cycle-dependent, rapamycin-resistant phosphorylation of ribosomal protein S6 at S240/244 Amino Acids. 39: 1487-1492. PMID 20464435 DOI: 10.1007/S00726-010-0615-2  0.376
2010 Shemon AN, Heil GL, Granovsky AE, Clark MM, McElheny D, Chimon A, Rosner MR, Koide S. Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands. Plos One. 5: e10479. PMID 20463977 DOI: 10.1371/Journal.Pone.0010479  0.411
2010 Valli A, Rosner M, Fuchs C, Siegel N, Bishop CE, Dolznig H, Mädel U, Feichtinger W, Atala A, Hengstschläger M. Embryoid body formation of human amniotic fluid stem cells depends on mTOR Oncogene. 29: 966-977. PMID 19935716 DOI: 10.1038/Onc.2009.405  0.377
2010 Rosner M, Siegel N, Valli A, Fuchs C, Hengstschläger M. mTOR phosphorylated at S2448 binds to raptor and rictor. Amino Acids. 38: 223-228. PMID 19145465 DOI: 10.1007/S00726-008-0230-7  0.453
2010 Menon J, Doebele RS, Schulze-Hoepfner FT, Rosner MR. Abstract 2379: Rap1 regulates angiogenesis in prostate tumors Cancer Research. 70: 2379-2379. DOI: 10.1158/1538-7445.Am10-2379  0.402
2009 Netzer N, Goodenbour JM, David A, Dittmar KA, Jones RB, Schneider JR, Boone D, Eves EM, Rosner MR, Gibbs JS, Embry A, Dolan B, Das S, Hickman HD, Berglund P, et al. Innate immune and chemically triggered oxidative stress modifies translational fidelity. Nature. 462: 522-6. PMID 19940929 DOI: 10.1038/Nature08576  0.304
2009 Pavon-Eternod M, Gomes S, Geslain R, Dai Q, Rosner MR, Pan T. tRNA over-expression in breast cancer and functional consequences. Nucleic Acids Research. 37: 7268-80. PMID 19783824 DOI: 10.1093/Nar/Gkp787  0.378
2009 Rosner M, Dolznig H, Fuchs C, Siegel N, Valli A, Hengstschläger M. CDKs as therapeutic targets for the human genetic disease tuberous sclerosis European Journal of Clinical Investigation. 39: 1033-1035. PMID 19744185 DOI: 10.1111/J.1365-2362.2009.02213.X  0.397
2009 Doebele RC, Schulze-Hoepfner FT, Hong J, Chlenski A, Zeitlin BD, Goel K, Gomes S, Liu Y, Abe MK, Nor JE, Lingen MW, Rosner MR. A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis. Blood. 114: 4592-600. PMID 19710505 DOI: 10.1182/Blood-2009-04-217042  0.758
2009 Cohen EE, Rosner MR. MicroRNA-regulated feed forward loop network. Cell Cycle (Georgetown, Tex.). 8: 2477-8. PMID 19657226 DOI: 10.4161/Cc.8.16.9271  0.411
2009 Chou YH, Kuo WL, Rosner MR, Tang WJ, Goldman RD. Structural changes in intermediate filament networks alter the activity of insulin-degrading enzyme. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3734-42. PMID 19584300 DOI: 10.1096/Fj.09-137455  0.376
2009 Shemon AN, Eves EM, Clark MC, Heil G, Granovsky A, Zeng L, Imamoto A, Koide S, Rosner MR. Raf Kinase Inhibitory Protein protects cells against locostatin-mediated inhibition of migration. Plos One. 4: e6028. PMID 19551145 DOI: 10.1371/Journal.Pone.0006028  0.482
2009 Dangi-Garimella S, Yun J, Eves EM, Newman M, Erkeland SJ, Hammond SM, Minn AJ, Rosner MR. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. The Embo Journal. 28: 347-58. PMID 19153603 DOI: 10.1038/Emboj.2008.294  0.495
2009 Cohen EE, Zhu H, Lingen MW, Martin LE, Kuo WL, Choi EA, Kocherginsky M, Parker JS, Chung CH, Rosner MR. A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle. Cancer Research. 69: 65-74. PMID 19117988 DOI: 10.1158/0008-5472.Can-08-0377  0.483
2009 Granovsky AE, Clark MC, McElheny D, Heil G, Hong J, Liu X, Kim Y, Joachimiak G, Joachimiak A, Koide S, Rosner MR. Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism. Molecular and Cellular Biology. 29: 1306-20. PMID 19103740 DOI: 10.1128/Mcb.01271-08  0.727
2009 Rosner M, Hanneder M, Siegel N, Valli A, Fuchs C, Hengstschläger M. Skp2 inversely correlates with p27 and tuberin in transformed cells Amino Acids. 37: 257-262. PMID 18604603 DOI: 10.1007/S00726-008-0141-7  0.375
2009 Burgstaller S, Rosner M, Lindengrün C, Hanneder M, Siegel N, Valli A, Fuchs C, Hengstschläger M. Tuberin, p27 and mTOR in different cells. Amino Acids. 36: 297-302. PMID 18386114 DOI: 10.1007/S00726-008-0066-1  0.469
2008 Yfanti C, Mengele K, Gkazepis A, Weirich G, Giersig C, Kuo WL, Tang WJ, Rosner M, Schmitt M. Expression of metalloprotease insulin-degrading enzyme insulysin in normal and malignant human tissues. International Journal of Molecular Medicine. 22: 421-31. PMID 18813847 DOI: 10.3892/Ijmm_00000038  0.353
2008 Weirich G, Mengele K, Yfanti C, Gkazepis A, Hellmann D, Welk A, Giersig C, Kuo WL, Rosner MR, Tang WJ, Schmitt M. Immunohistochemical evidence of ubiquitous distribution of the metalloendoprotease insulin-degrading enzyme (IDE; insulysin) in human non-malignant tissues and tumor cell lines. Biological Chemistry. 389: 1441-5. PMID 18783335 DOI: 10.1515/Bc.2008.157  0.36
2008 Zeng L, Imamoto A, Rosner MR. Raf kinase inhibitory protein (RKIP): a physiological regulator and future therapeutic target. Expert Opinion On Therapeutic Targets. 12: 1275-87. PMID 18781826 DOI: 10.1517/14728222.12.10.1275  0.422
2008 Granovsky AE, Rosner MR. Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor. Cell Research. 18: 452-7. PMID 18379591 DOI: 10.1615/Forumimmundisther.V2.I1.30  0.461
2008 Freilinger A, Rosner M, Hanneder M, Hengstschläger M. Ras mediates cell survival by regulating tuberin. Oncogene. 27: 2072-2083. PMID 17922028 DOI: 10.1038/Sj.Onc.1210844  0.319
2007 Hudelist G, Wagner T, Rosner M, Fink-Retter A, Gschwantler-Kaulich D, Czerwenka K, Kroiss R, Tea M, Pischinger K, Köstler WJ, Attems J, Mueller R, Blaukopf C, Kubista E, Hengstschläger M, et al. Intratumoral IGF-I protein expression is selectively upregulated in breast cancer patients with BRCA1/2 mutations. Endocrine-Related Cancer. 14: 1053-62. PMID 18045956 DOI: 10.1677/Erc-06-0075  0.377
2007 Hong J, Doebele RC, Lingen MW, Quilliam LA, Tang WJ, Rosner MR. Anthrax edema toxin inhibits endothelial cell chemotaxis via Epac and Rap1. The Journal of Biological Chemistry. 282: 19781-7. PMID 17491018 DOI: 10.1074/Jbc.M700128200  0.694
2007 Rosner M, Hengstschläger M. Cytoplasmic/nuclear localization of tuberin in different cell lines. Amino Acids. 33: 575-579. PMID 17458623 DOI: 10.1007/S00726-007-0541-0  0.42
2007 Rosner M, Hanneder M, Freilinger A, Hengstschläger M. Nuclear/cytoplasmic localization of Akt activity in the cell cycle. Amino Acids. 32: 341-345. PMID 17357828 DOI: 10.1007/S00726-007-0509-0  0.49
2007 Rosner MR. MAP kinase meets mitosis: a role for Raf Kinase Inhibitory Protein in spindle checkpoint regulation. Cell Division. 2: 1. PMID 17214889 DOI: 10.1186/1747-1028-2-1  0.491
2007 Radulescu RT, Hufnagel C, Luppa P, Hellebrand H, Kuo WL, Rosner MR, Harbeck N, Giersig C, Meindl A, Schmitt M, Weirich G. Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels. International Journal of Oncology. 30: 73-80. PMID 17143514 DOI: 10.3892/Ijo.30.1.73  0.346
2007 Rosner M, Freilinger A, Hengstschläger M. Akt regulates nuclear/cytoplasmic localization of tuberin. Oncogene. 26: 521-531. PMID 16862180 DOI: 10.1038/Sj.Onc.1209812  0.482
2006 Eves EM, Shapiro P, Naik K, Klein UR, Trakul N, Rosner MR. Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. Molecular Cell. 23: 561-74. PMID 16916643 DOI: 10.1016/J.Molcel.2006.07.015  0.782
2006 Cohen EE, Lingen MW, Zhu B, Zhu H, Straza MW, Pierce C, Martin LE, Rosner MR. Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase. Cancer Research. 66: 6296-303. PMID 16778206 DOI: 10.1158/0008-5472.Can-05-3139  0.525
2006 Freilinger A, Rosner M, Hengstschläger M. Tuberin negatively affects BCL-2’s cell survival function Amino Acids. 30: 391-396. PMID 16773241 DOI: 10.1007/S00726-006-0359-1  0.389
2006 Freilinger A, Rosner M, Krupitza G, Nishino M, Lubec G, Korsmeyer SJ, Hengstschläger M. Tuberin activates the proapoptotic molecule BAD. Oncogene. 25: 6467-6479. PMID 16702951 DOI: 10.1038/Sj.Onc.1209660  0.456
2006 Liu J, Yang D, Minemoto Y, Leitges M, Rosner MR, Lin A. NF-kappaB is required for UV-induced JNK activation via induction of PKCdelta. Molecular Cell. 21: 467-80. PMID 16483929 DOI: 10.1016/J.Molcel.2005.12.020  0.334
2006 Clark MC, McElheny D, Wojcik J, Kurutz J, Rosner MR, Koide S. NMR assignment of rat Raf kinase inhibitor protein. Journal of Biomolecular Nmr. 36: 4. PMID 16456706 DOI: 10.1007/S10858-005-4424-Y  0.374
2006 Rosner M, Hengstschläger M. 14-3-3 proteins are involved in the regulation of mammalian cell proliferation Amino Acids. 30: 105-109. PMID 16133763 DOI: 10.1007/S00726-005-0240-7  0.422
2005 Lin C, Franco B, Rosner MR. CDKL5/Stk9 kinase inactivation is associated with neuronal developmental disorders. Human Molecular Genetics. 14: 3775-86. PMID 16330482 DOI: 10.1093/Hmg/Ddi391  0.518
2005 Hong J, Beeler J, Zhukovskaya NL, He W, Tang WJ, Rosner MR. Anthrax edema factor potency depends on mode of cell entry. Biochemical and Biophysical Research Communications. 335: 850-7. PMID 16099427 DOI: 10.1016/J.Bbrc.2005.07.132  0.7
2005 Trakul N, Menard RE, Schade GR, Qian Z, Rosner MR. Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation. The Journal of Biological Chemistry. 280: 24931-40. PMID 15886202 DOI: 10.1074/Jbc.M413929200  0.788
2005 Trakul N, Rosner MR. Modulation of the MAP kinase signaling cascade by Raf kinase inhibitory protein. Cell Research. 15: 19-23. PMID 15686621 DOI: 10.1038/Sj.Cr.7290258  0.78
2004 Kuo WL, Duke CJ, Abe MK, Kaplan EL, Gomes S, Rosner MR. ERK7 expression and kinase activity is regulated by the ubiquitin-proteosome pathway. The Journal of Biological Chemistry. 279: 23073-81. PMID 15033983 DOI: 10.1074/Jbc.M313696200  0.463
2004 Zhou L, Li J, Goldsmith AM, Newcomb DC, Giannola DM, Vosk RG, Eves EM, Rosner MR, Solway J, Hershenson MB. Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma. American Journal of Respiratory and Critical Care Medicine. 169: 703-11. PMID 14693670 DOI: 10.1164/Rccm.200307-964Oc  0.389
2003 Pugazhenthi S, Nesterova A, Jambal P, Audesirk G, Kern M, Cabell L, Eves E, Rosner MR, Boxer LM, Reusch JE. Oxidative stress-mediated down-regulation of bcl-2 promoter in hippocampal neurons. Journal of Neurochemistry. 84: 982-96. PMID 12603823 DOI: 10.1046/J.1471-4159.2003.01606.X  0.339
2003 Corbit KC, Trakul N, Eves EM, Diaz B, Marshall M, Rosner MR. Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. The Journal of Biological Chemistry. 278: 13061-8. PMID 12551925 DOI: 10.1074/Jbc.M210015200  0.796
2002 Tang F, Tang G, Xiang J, Dai Q, Rosner MR, Lin A. The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Molecular and Cellular Biology. 22: 8571-9. PMID 12446776 DOI: 10.1128/Mcb.22.24.8571-8579.2002  0.328
2002 Page K, Li J, Corbit KC, Rumilla KM, Soh JW, Weinstein IB, Albanese C, Pestell RG, Rosner MR, Hershenson MB. Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-delta. American Journal of Respiratory Cell and Molecular Biology. 27: 204-13. PMID 12151312 DOI: 10.1165/Ajrcmb.27.2.20010016Oc  0.77
2002 Hong J, Yoshida K, Rosner MR. Characterization of a cysteine proteinase inhibitor induced during neuronal cell differentiation. Journal of Neurochemistry. 81: 922-34. PMID 12065604 DOI: 10.1046/J.1471-4159.2002.00882.X  0.671
2002 Abe MK, Saelzler MP, Espinosa R, Kahle KT, Hershenson MB, Le Beau MM, Rosner MR. ERK8, a new member of the mitogen-activated protein kinase family. The Journal of Biological Chemistry. 277: 16733-43. PMID 11875070 DOI: 10.1074/Jbc.M112483200  0.437
2001 Qian Z, Lin C, Espinosa R, LeBeau M, Rosner MR. Cloning and characterization of MST4, a novel Ste20-like kinase. The Journal of Biological Chemistry. 276: 22439-45. PMID 11306563 DOI: 10.1074/Jbc.M009323200  0.556
2001 Abe MK, Kahle KT, Saelzler MP, Orth K, Dixon JE, Rosner MR. ERK7 is an autoactivated member of the MAPK family. The Journal of Biological Chemistry. 276: 21272-9. PMID 11287416 DOI: 10.1074/Jbc.M100026200  0.454
2001 Janulis M, Trakul N, Greene G, Schaefer EM, Lee JD, Rosner MR. A novel mitogen-activated protein kinase is responsive to Raf and mediates growth factor specificity. Molecular and Cellular Biology. 21: 2235-47. PMID 11238956 DOI: 10.1128/Mcb.21.6.2235-2247.2001  0.782
2001 Eves EM, Skoczylas C, Yoshida K, Alnemri ES, Rosner MR. FGF Induces a Switch in Death Receptor Pathways in Neuronal Cells The Journal of Neuroscience. 21: 4996-5006. DOI: 10.1523/Jneurosci.21-14-04996.2001  0.353
2000 Corbit KC, Soh JW, Yoshida K, Eves EM, Weinstein IB, Rosner MR. Different protein kinase C isoforms determine growth factor specificity in neuronal cells. Molecular and Cellular Biology. 20: 5392-403. PMID 10891480 DOI: 10.1128/Mcb.20.15.5392-5403.2000  0.8
2000 Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ. Neurons Regulate Extracellular Levels of Amyloid β-Protein via Proteolysis by Insulin-Degrading Enzyme The Journal of Neuroscience. 20: 1657-1665. DOI: 10.1523/Jneurosci.20-05-01657.2000  0.308
1999 Chao KS, Hsu JS, Xu J, Ezekiel UR, Eves E, Rosner M, Hsu CY. Differential effect of cycloheximide on neuronal and glioma cells treated with chemotherapy and radiation. Journal of Neuro-Oncology. 45: 19-26. PMID 10728906 DOI: 10.1023/A:1006342006836  0.317
1999 Gomes I, Xiong W, Miki T, Rosner MR. A proline- and glutamine-rich protein promotes apoptosis in neuronal cells. Journal of Neurochemistry. 73: 612-22. PMID 10428057 DOI: 10.1046/J.1471-4159.1999.0730612.X  0.357
1999 Page K, Li J, Hodge JA, Liu PT, Vanden Hoek TL, Becker LB, Pestell RG, Rosner MR, Hershenson MB. Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells. The Journal of Biological Chemistry. 274: 22065-71. PMID 10419534 DOI: 10.1074/Jbc.274.31.22065  0.433
1999 Corbit KC, Foster DA, Rosner MR. Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells. Molecular and Cellular Biology. 19: 4209-18. PMID 10330161 DOI: 10.1128/Mcb.19.6.4209  0.796
1999 Abe MK, Kuo WL, Hershenson MB, Rosner MR. Extracellular signal-regulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth. Molecular and Cellular Biology. 19: 1301-12. PMID 9891064 DOI: 10.1128/Mcb.19.2.1301  0.473
1999 Qian Z, Okuhara D, Abe MK, Rosner MR. Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel. The Journal of Biological Chemistry. 274: 1621-7. PMID 9880541 DOI: 10.1074/Jbc.274.3.1621  0.437
1999 Czyzewski E, Gomes I, Corbit K, Rosner M, Mehta M. 27 The role of the MAPK signaling pathway in expression of the pro-apoptotic protein, PQR/TDAG51, in differentiating neuronal cells vs irradiated primitive neuroectodermal tumor cells International Journal of Radiation Oncology*Biology*Physics. 45: 160-161. DOI: 10.1016/S0360-3016(99)90045-7  0.771
1998 Chung KC, Gomes I, Wang D, Lau LF, Rosner MR. Raf and fibroblast growth factor phosphorylate Elk1 and activate the serum response element of the immediate early gene pip92 by mitogen-activated protein kinase-independent as well as -dependent signaling pathways. Molecular and Cellular Biology. 18: 2272-81. PMID 9528798 DOI: 10.1128/Mcb.18.4.2272  0.496
1998 Eves EM, Xiong W, Bellacosa A, Kennedy SG, Tsichlis PN, Rosner MR, Hay N. Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line Molecular and Cellular Biology. 18: 2143-2152. PMID 9528786 DOI: 10.1128/Mcb.18.4.2143  0.47
1997 Xiong W, Pestell R, Rosner MR. Role of cyclins in neuronal differentiation of immortalized hippocampal cells Molecular and Cellular Biology. 17: 6585-6597. PMID 9343422 DOI: 10.1128/Mcb.17.11.6585  0.365
1997 Kuo WL, Chung KC, Rosner MR. Differentiation of central nervous system neuronal cells by fibroblast-derived growth factor requires at least two signaling pathways: roles for Ras and Src. Molecular and Cellular Biology. 17: 4633-43. PMID 9234720 DOI: 10.1128/Mcb.17.8.4633  0.442
1997 Xiong W, Pestell RG, Watanabe G, Li J, Rosner MR, Hershenson MB. Cyclin D1 is required for S phase traversal in bovine tracheal myocytes. The American Journal of Physiology. 272: L1205-10. PMID 9227524 DOI: 10.1152/Ajplung.1997.272.6.L1205  0.366
1997 Morrison P, Chung KC, Rosner MR. Mutation of Di-leucine residues in the juxtamembrane region alters EGF receptor expression. Biochemistry. 35: 14618-24. PMID 8931560 DOI: 10.1021/Bi961630+  0.364
1996 Eves EM, Boise LH, Thompson CB, Wagner AJ, Hay N, Rosner MR. Apoptosis induced by differentiation or serum deprivation in an immortalized central nervous system neuronal cell line Journal of Neurochemistry. 67: 1908-1920. PMID 8863495 DOI: 10.1046/J.1471-4159.1996.67051908.X  0.336
1996 Morrison P, Saltiel AR, Rosner MR. Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C Journal of Biological Chemistry. 271: 12891-12896. PMID 8662819 DOI: 10.1074/Jbc.271.22.12891  0.463
1996 Kuo WL, Abe M, Rhee J, Eves EM, McCarthy SA, Yan M, Templeton DJ, McMahon M, Rosner MR. Raf, but not MEK or ERK, is sufficient for differentiation of hippocampal neuronal cells. Molecular and Cellular Biology. 16: 1458-70. PMID 8657119 DOI: 10.1128/Mcb.16.4.1458  0.417
1995 Hershenson MB, Chao TS, Abe MK, Gomes I, Kelleher MD, Solway J, Rosner MR. Histamine antagonizes serotonin and growth factor-induced mitogen-activated protein kinase activation in bovine tracheal smooth muscle cells. The Journal of Biological Chemistry. 270: 19908-13. PMID 7650005 DOI: 10.1074/Jbc.270.34.19908  0.424
1995 Kelleher MD, Abe MK, Chao TS, Jain M, Green JM, Solway J, Rosner MR, Hershenson MB. Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis. The American Journal of Physiology. 268: L894-901. PMID 7611431 DOI: 10.1152/Ajplung.1995.268.6.L894  0.422
1995 Eves EM, Wainer BH, Rosner MR. Generation of neuronal cell lines from mitotic and postmitotic rat hippocampal cultures Methods: a Companion to Methods in Enzymology. 7: 297-302. DOI: 10.1006/Meth.1995.1035  0.302
1995 Englert C, Hou X, Maheswaran S, Bennett P, Ngwu C, Re GG, Garvin AJ, Rosner MR, Haber DA. WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis. The Embo Journal. 14: 4662-4675. DOI: 10.1002/J.1460-2075.1995.Tb00148.X  0.404
1994 Abe MK, Chao TS, Solway J, Rosner MR, Hershenson MB. Hydrogen peroxide stimulates mitogen-activated protein kinase in bovine tracheal myocytes: implications for human airway disease. American Journal of Respiratory Cell and Molecular Biology. 11: 577-85. PMID 7946386 DOI: 10.1165/Ajrcmb.11.5.7946386  0.453
1993 Hoffman BL, Takishima K, Rosner MR, Carlin C. Adenovirus and protein kinase C have distinct molecular requirements for regulating epidermal growth factor receptor trafficking. Journal of Cellular Physiology. 157: 535-43. PMID 8253865 DOI: 10.1002/Jcp.1041570313  0.437
1993 Tucker MS, Eves EM, Wainer BH, Rosner MR. Activation of mitogen-activated protein kinase by epidermal growth factor in hippocampal neurons and neuronal cell lines. Journal of Neurochemistry. 61: 1376-87. PMID 7690847 DOI: 10.1111/J.1471-4159.1993.Tb13631.X  0.41
1992 Suganuma M, Fujiki H, Okabe S, Nishiwaki S, Brautigan D, Ingebritsen TS, Rosner MR. Structurally different members of the okadaic acid class selectively inhibit protein serine/threonine but not tyrosine phosphatase activity. Toxicon : Official Journal of the International Society On Toxinology. 30: 873-8. PMID 1326138 DOI: 10.1016/0041-0101(92)90385-I  0.308
1991 Kuo WL, Gehm BD, Rosner MR. Cloning and expression of the cDNA for a Drosophila insulin-degrading enzyme. Molecular Endocrinology (Baltimore, Md.). 4: 1580-91. PMID 2126597 DOI: 10.1210/Mend-4-10-1580  0.319
1991 Takishima K, Griswold-Prenner I, Ingebritsen T, Rosner MR. Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase. Proceedings of the National Academy of Sciences of the United States of America. 88: 2520-4. PMID 1848706 DOI: 10.1073/Pnas.88.6.2520  0.404
1991 Gehm BD, Rosner MR. Regulation of insulin, epidermal growth factor, and transforming growth factor-alpha levels by growth factor-degrading enzymes. Endocrinology. 128: 1603-10. PMID 1847863 DOI: 10.1210/Endo-128-3-1603  0.302
1989 Takishima K, Friedman B, Fujiki H, Rosner MR. Thapsigargin, a novel promoter, phosphorylates the epidermal growth factor receptor at threonine 669. Biochemical and Biophysical Research Communications. 157: 740-6. PMID 3202876 DOI: 10.1016/S0006-291X(88)80312-7  0.45
1989 Hicks K, Friedman B, Rosner MR. Basic and acidic fibroblast growth factors modulate the epidermal growth factor receptor by a protein kinase C-independent pathway. Biochemical and Biophysical Research Communications. 164: 796-803. PMID 2818588 DOI: 10.1016/0006-291X(89)91529-5  0.412
1989 Hicks K, Friedman B, Rosner MR. Basic fibroblast-like growth factor is present in the conditioned medium of simian sarcoma virus transformed NRK cells. Biochemical and Biophysical Research Communications. 164: 1323-30. PMID 2556126 DOI: 10.1016/0006-291X(89)91814-7  0.359
1989 Friedman BA, van Amsterdam J, Fujiki H, Rosner MR. Phosphorylation at threonine-654 is not required for negative regulation of the epidermal growth factor receptor by non-phorbol tumor promoters. Proceedings of the National Academy of Sciences of the United States of America. 86: 812-6. PMID 2492663 DOI: 10.1073/Pnas.86.3.812  0.452
1988 Stoppelli MP, Garcia JV, Decker SJ, Rosner MR. Developmental regulation of an insulin-degrading enzyme from Drosophila melanogaster Proceedings of the National Academy of Sciences of the United States of America. 85: 3469-3473. PMID 3130628 DOI: 10.1073/Pnas.85.10.3469  0.316
1987 Friedman BA, Rosner MR. Growth factors modify the epidermal growth factor receptor through multiple pathways. Journal of Cellular Biochemistry. 34: 1-11. PMID 3584259 DOI: 10.1002/Jcb.240340102  0.462
1987 McCaffrey PG, Rosner MR, Kikkawa U, Sekiguchi K, Ogita K, Ase K, Nishizuka Y. Characterization of protein kinase C from normal and transformed cultured murine fibroblasts Biochemical and Biophysical Research Communications. 146: 140-146. PMID 3300649 DOI: 10.1016/0006-291X(87)90702-9  0.364
1987 Garcia JV, Stoppelli MP, Thompson KL, Decker SJ, Rosner MR. Characterization of a Drosophila protein that binds both epidermal growth factor and insulin-related growth factors. The Journal of Cell Biology. 105: 449-56. PMID 3112166 DOI: 10.1083/Jcb.105.1.449  0.306
1986 Hung MC, Thompson KL, Chiu IM, Rosner MR. Characterization of rodent epidermal growth factor receptor transcripts using a mouse genomic probe. Biochemical and Biophysical Research Communications. 141: 1109-15. PMID 2434080 DOI: 10.1016/S0006-291X(86)80158-9  0.327
1985 Thompson KL, Decker SJ, Rosner MR. Identification of a novel receptor in Drosophila for both epidermal growth factor and insulin. Proceedings of the National Academy of Sciences of the United States of America. 82: 8443-7. PMID 3001704 DOI: 10.1073/Pnas.82.24.8443  0.31
1984 Friedman B, Frackelton AR, Ross AH, Connors JM, Fujiki H, Sugimura T, Rosner MR. Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor. Proceedings of the National Academy of Sciences of the United States of America. 81: 3034-8. PMID 6328489 DOI: 10.1073/Pnas.81.10.3034  0.637
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