| Year |
Citation |
Score |
| 2022 |
Macé K, Vadakkepat AK, Redzej A, Lukoyanova N, Oomen C, Braun N, Ukleja M, Lu F, Costa TRD, Orlova EV, Baker D, Cong Q, Waksman G. Cryo-EM structure of a type IV secretion system. Nature. PMID 35732732 DOI: 10.1038/s41586-022-04859-y |
0.307 |
|
| 2020 |
Meir A, Macé K, Lukoyanova N, Chetrit D, Hospenthal MK, Redzej A, Roy C, Waksman G. Mechanism of effector capture and delivery by the type IV secretion system from Legionella pneumophila. Nature Communications. 11: 2864. PMID 32513920 DOI: 10.1038/S41467-020-16681-Z |
0.411 |
|
| 2019 |
Williams AH, Redzej A, Rolhion N, Costa TRD, Rifflet A, Waksman G, Cossart P. The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation. Nature Communications. 10: 3005. PMID 31285450 DOI: 10.1038/S41467-019-10782-0 |
0.389 |
|
| 2019 |
Hospenthal MK, Waksman G. The Remarkable Biomechanical Properties of the Type 1 Chaperone-Usher Pilus: A Structural and Molecular Perspective. Microbiology Spectrum. 7. PMID 30681068 DOI: 10.1128/Microbiolspec.Psib-0010-2018 |
0.332 |
|
| 2018 |
Sgro GG, Costa TRD, Cenens W, Souza DP, Cassago A, Coutinho de Oliveira L, Salinas RK, Portugal RV, Farah CS, Waksman G. Cryo-EM structure of the bacteria-killing type IV secretion system core complex from Xanthomonas citri. Nature Microbiology. PMID 30349081 DOI: 10.2210/Pdb6Gyb/Pdb |
0.419 |
|
| 2018 |
Prevost MS, Waksman G. X-ray Crystal Structures of the Type IVb Secretion System DotB ATPases. Protein Science : a Publication of the Protein Society. PMID 29770512 DOI: 10.1002/Pro.3439 |
0.46 |
|
| 2018 |
Galán JE, Waksman G. Protein-Injection Machines in Bacteria. Cell. 172: 1306-1318. PMID 29522749 DOI: 10.1016/J.Cell.2018.01.034 |
0.354 |
|
| 2018 |
Meir A, Chetrit D, Liu L, Roy CR, Waksman G. Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system. Nature Communications. 9: 507. PMID 29410427 DOI: 10.1038/S41467-017-02578-X |
0.445 |
|
| 2018 |
Trokter M, Waksman G. Translocation through the conjugative Type 4 secretion system requires unfolding of its protein substrate. Journal of Bacteriology. PMID 29311273 DOI: 10.1128/Jb.00615-17 |
0.401 |
|
| 2017 |
Terradot L, Bergé C, Waksman G. Structural and Molecular Biology of Type IV Secretion Systems. Current Topics in Microbiology and Immunology. 413: 31-60. PMID 29536354 DOI: 10.1007/978-3-319-75241-9_2 |
0.426 |
|
| 2017 |
Grohmann E, Christie PJ, Waksman G, Backert S. Type IV secretion in Gram-negative and Gram-positive bacteria. Molecular Microbiology. PMID 29235173 DOI: 10.1111/Mmi.13896 |
0.402 |
|
| 2017 |
Hospenthal MK, Zyla D, Costa TRD, Redzej A, Giese C, Lillington J, Glockshuber R, Waksman G. The Cryoelectron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod. Structure (London, England : 1993). PMID 29129382 DOI: 10.1016/J.Str.2017.10.004 |
0.413 |
|
| 2017 |
Pinotsis N, Waksman G. Crystal structure of the Legionella pneumophila Lpg2936 in complex with the cofactor S-adenosyl-L-methionine reveals novel insights into the mechanism of RsmE family methyltransferases. Protein Science : a Publication of the Protein Society. PMID 28940762 DOI: 10.1002/Pro.3305 |
0.442 |
|
| 2017 |
Redzej A, Ukleja M, Connery S, Trokter M, Felisberto-Rodrigues C, Cryar A, Thalassinos K, Hayward RD, Orlova EV, Waksman G. Structure of a VirD4 coupling protein bound to a VirB type IV secretion machinery. The Embo Journal. PMID 28923826 DOI: 10.15252/Embj.201796629 |
0.437 |
|
| 2017 |
Prevost MS, Pinotsis N, Dumoux M, Hayward RD, Waksman G. The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery. Scientific Reports. 7: 9450. PMID 28842705 DOI: 10.1038/S41598-017-10249-6 |
0.441 |
|
| 2017 |
Goosens VJ, Busch A, Georgiadou M, Castagnini M, Forest KT, Waksman G, Pelicic V. Reconstitution of a minimal machinery capable of assembling periplasmic type IV pili. Proceedings of the National Academy of Sciences of the United States of America. PMID 28588140 DOI: 10.1073/Pnas.1618539114 |
0.391 |
|
| 2017 |
Waksman G. Structural and Molecular Biology of a Protein-Polymerising Nanomachine for Pilus Biogenesis. Journal of Molecular Biology. PMID 28551336 DOI: 10.1016/J.Jmb.2017.05.016 |
0.391 |
|
| 2017 |
Hospenthal MK, Costa TRD, Waksman G. A comprehensive guide to pilus biogenesis in Gram-negative bacteria. Nature Reviews. Microbiology. 15: 365-379. PMID 28496159 DOI: 10.1038/Nrmicro.2017.40 |
0.41 |
|
| 2017 |
Ilangovan A, Kay CWM, Roier S, El Mkami H, Salvadori E, Zechner EL, Zanetti G, Waksman G. Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation. Cell. PMID 28457609 DOI: 10.1016/J.Cell.2017.04.010 |
0.338 |
|
| 2017 |
Gordon JE, Costa TRD, Patel RS, Gonzalez-Rivera C, Sarkar MK, Orlova EV, Waksman G, Christie PJ. Use of Chimeric Type IV Secretion Systems to Define Contributions of Outer Membrane Subassemblies for Contact-Dependent Translocation. Molecular Microbiology. PMID 28452085 DOI: 10.1111/Mmi.13700 |
0.407 |
|
| 2017 |
Pinotsis N, Waksman G. Structure of the WipA protein reveals a novel tyrosine protein phosphatase effector from Legionella pneumophila. The Journal of Biological Chemistry. PMID 28389563 DOI: 10.1074/Jbc.M117.781948 |
0.478 |
|
| 2016 |
Farabella I, Pham T, Henderson NS, Geibel S, Phan G, Thanassi DG, Delcour AH, Waksman G, Topf M. Correction: Allosteric signalling in the outer membrane translocation domain of PapC usher. Elife. 5. PMID 27676114 DOI: 10.7554/Elife.21585 |
0.359 |
|
| 2016 |
Costa TR, Ilangovan A, Ukleja M, Redzej A, Santini JM, Smith TK, Egelman EH, Waksman G. Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex. Cell. 166: 1436-1444.e10. PMID 27610568 DOI: 10.1016/J.Cell.2016.08.025 |
0.338 |
|
| 2016 |
Stubenrauch C, Belousoff MJ, Hay ID, Shen HH, Lillington J, Tuck KL, Peters KM, Phan MD, Lo AW, Schembri MA, Strugnell RA, Waksman G, Lithgow T. Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine. Nature Microbiology. 1: 16064. PMID 27572967 DOI: 10.1038/Nmicrobiol.2016.64 |
0.368 |
|
| 2016 |
Hospenthal MK, Redzej A, Dodson K, Ukleja M, Frenz B, Rodrigues C, Hultgren SJ, DiMaio F, Egelman EH, Waksman G. Structure of a Chaperone-Usher Pilus Reveals the Molecular Basis of Rod Uncoiling. Cell. 164: 269-78. PMID 26724865 DOI: 10.1016/J.Cell.2015.11.049 |
0.38 |
|
| 2016 |
Papaioannou D, Geibel S, Kunze MB, Kay CW, Waksman G. Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide. Protein Science : a Publication of the Protein Society. 25: 627-37. PMID 26645482 DOI: 10.1002/Pro.2856 |
0.475 |
|
| 2015 |
Chandran Darbari V, Waksman G. Structural Biology of Bacterial Type IV Secretion Systems. Annual Review of Biochemistry. 84: 603-29. PMID 26034891 DOI: 10.1146/Annurev-Biochem-062911-102821 |
0.406 |
|
| 2015 |
Kaplan M, Cukkemane A, van Zundert GC, Narasimhan S, Daniëls M, Mance D, Waksman G, Bonvin AM, Fronzes R, Folkers GE, Baldus M. Probing a cell-embedded megadalton protein complex by DNP-supported solid-state NMR. Nature Methods. PMID 25984698 DOI: 10.1038/Nmeth.3406 |
0.694 |
|
| 2015 |
Costa TR, Felisberto-Rodrigues C, Meir A, Prevost MS, Redzej A, Trokter M, Waksman G. Secretion systems in Gram-negative bacteria: structural and mechanistic insights. Nature Reviews. Microbiology. 13: 343-59. PMID 25978706 DOI: 10.1038/Nrmicro3456 |
0.433 |
|
| 2015 |
Ilangovan A, Connery S, Waksman G. Structural biology of the Gram-negative bacterial conjugation systems. Trends in Microbiology. 23: 301-10. PMID 25825348 DOI: 10.1016/J.Tim.2015.02.012 |
0.39 |
|
| 2015 |
Garnett JA, Muhl D, Douse CH, Hui K, Busch A, Omisore A, Yang Y, Simpson P, Marchant J, Waksman G, Matthews S, Filloux A. Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation. Protein Science : a Publication of the Protein Society. 24: 670-87. PMID 25641651 DOI: 10.1002/Pro.2640 |
0.45 |
|
| 2015 |
Busch A, Phan G, Waksman G. Molecular mechanism of bacterial type 1 and P pili assembly. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 373. PMID 25624519 DOI: 10.1098/Rsta.2013.0153 |
0.401 |
|
| 2014 |
Sayer JR, Walldén K, Pesnot T, Campbell F, Gane PJ, Simone M, Koss H, Buelens F, Boyle TP, Selwood DL, Waksman G, Tabor AB. 2- and 3-substituted imidazo[1,2-a]pyrazines as inhibitors of bacterial type IV secretion. Bioorganic & Medicinal Chemistry. 22: 6459-70. PMID 25438770 DOI: 10.1016/J.Bmc.2014.09.036 |
0.323 |
|
| 2014 |
Farabella I, Pham T, Henderson NS, Geibel S, Phan G, Thanassi DG, Delcour AH, Waksman G, Topf M. Allosteric signalling in the outer membrane translocation domain of PapC usher. Elife. 3. PMID 25271373 DOI: 10.7554/Elife.03532 |
0.381 |
|
| 2014 |
Gonen T, Waksman G. Editorial overview: Membranes: recent methods in the study of membrane protein structure. Current Opinion in Structural Biology. 27: iv-v. PMID 25242735 DOI: 10.1016/J.Sbi.2014.09.002 |
0.37 |
|
| 2014 |
Trokter M, Felisberto-Rodrigues C, Christie PJ, Waksman G. Recent advances in the structural and molecular biology of type IV secretion systems. Current Opinion in Structural Biology. 27: 16-23. PMID 24709394 DOI: 10.1016/J.Sbi.2014.02.006 |
0.371 |
|
| 2014 |
Low HH, Gubellini F, Rivera-Calzada A, Braun N, Connery S, Dujeancourt A, Lu F, Redzej A, Fronzes R, Orlova EV, Waksman G. Structure of a type IV secretion system Nature. 508: 550-553. PMID 24670658 DOI: 10.1038/Nature13081 |
0.721 |
|
| 2014 |
Waksman G, Orlova EV. Structural organisation of the type IV secretion systems. Current Opinion in Microbiology. 17: 24-31. PMID 24581689 DOI: 10.1016/J.Mib.2013.11.001 |
0.394 |
|
| 2014 |
Lo AW, Van de Water K, Gane PJ, Chan AW, Steadman D, Stevens K, Selwood DL, Waksman G, Remaut H. Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization. The Journal of Antimicrobial Chemotherapy. 69: 1017-26. PMID 24324225 DOI: 10.1093/Jac/Dkt467 |
0.326 |
|
| 2014 |
Geibel S, Waksman G. The molecular dissection of the chaperone-usher pathway. Biochimica Et Biophysica Acta. 1843: 1559-67. PMID 24140205 DOI: 10.1016/J.Bbamcr.2013.09.023 |
0.348 |
|
| 2014 |
Farabella I, Pham T, Henderson NS, Geibel S, Phan G, Thanassi DG, Delcour AH, Waksman G, Topf M. Author response: Allosteric signalling in the outer membrane translocation domain of PapC usher Elife. DOI: 10.7554/Elife.03532.020 |
0.344 |
|
| 2014 |
Waksman G. Pilus biogenesis at the outer membrane of bacterial pathogens Acta Crystallographica Section A. 70. DOI: 10.1107/S205327331409425X |
0.302 |
|
| 2014 |
Pham T, Henderson NS, Phan G, Volkan E, Hultgren S, Waksman G, Thanassi DG, Delcour AH. Electrophysiological Analysis of PapC Mutants Provides Insights into the Mechanism of Plug Displacement Biophysical Journal. 106: 557a. DOI: 10.1016/J.Bpj.2013.11.3098 |
0.376 |
|
| 2013 |
Lillington J, Waksman G. Ordered and ushered; the assembly and translocation of the adhesive type I and p pili. Biology. 2: 841-60. PMID 24833049 DOI: 10.3390/Biology2030841 |
0.389 |
|
| 2013 |
Volkan E, Kalas V, Pinkner JS, Dodson KW, Henderson NS, Pham T, Waksman G, Delcour AH, Thanassi DG, Hultgren SJ. Molecular basis of usher pore gating in Escherichia coli pilus biogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 20741-6. PMID 24297893 DOI: 10.1073/Pnas.1320528110 |
0.459 |
|
| 2013 |
Lithgow T, Waksman G. Seaside transportation--from structure to function of translocation machines. Embo Reports. 14: 585-7. PMID 23764920 DOI: 10.1038/Embor.2013.79 |
0.31 |
|
| 2013 |
Redzej A, Ilangovan A, Lang S, Gruber CJ, Topf M, Zangger K, Zechner EL, Waksman G. Structure of a translocation signal domain mediating conjugative transfer by type IV secretion systems. Molecular Microbiology. 89: 324-33. PMID 23710762 DOI: 10.1111/Mmi.12275 |
0.465 |
|
| 2013 |
Geibel S, Procko E, Hultgren SJ, Baker D, Waksman G. Structural and energetic basis of folded-protein transport by the FimD usher. Nature. 496: 243-6. PMID 23579681 DOI: 10.1038/Nature12007 |
0.452 |
|
| 2013 |
Rivera-Calzada A, Fronzes R, Savva CG, Chandran V, Lian PW, Laeremans T, Pardon E, Steyaert J, Remaut H, Waksman G, Orlova EV. Structure of a bacterial type IV secretion core complex at subnanometre resolution. The Embo Journal. 32: 1195-204. PMID 23511972 DOI: 10.1038/Emboj.2013.58 |
0.705 |
|
| 2013 |
Allen WJ, Phan G, Hultgren SJ, Waksman G. Dissection of pilus tip assembly by the FimD usher monomer. Journal of Molecular Biology. 425: 958-67. PMID 23295826 DOI: 10.1016/J.Jmb.2012.12.024 |
0.386 |
|
| 2012 |
Ford B, Verger D, Dodson K, Volkan E, Kostakioti M, Elam J, Pinkner J, Waksman G, Hultgren S. The structure of the PapD-PapGII pilin complex reveals an open and flexible P5 pocket. Journal of Bacteriology. 194: 6390-7. PMID 23002225 DOI: 10.1128/Jb.06651-11 |
0.476 |
|
| 2012 |
Rêgo AT, Johnson JG, Gelbel S, Enguita FJ, Clegg S, Waksman G. Crystal structure of the MrkD1P receptor binding domain of Klebsiella pneumoniae and identification of the human collagen V binding interface. Molecular Microbiology. 86: 882-93. PMID 22988966 DOI: 10.1111/Mmi.12023 |
0.431 |
|
| 2012 |
Gonen T, Waksman G. Recent progress in membrane protein structures and investigation methods. Current Opinion in Structural Biology. 22: 467-8. PMID 22819667 DOI: 10.1016/J.Sbi.2012.07.002 |
0.325 |
|
| 2012 |
Walldén K, Williams R, Yan J, Lian PW, Wang L, Thalassinos K, Orlova EV, Waksman G. Structure of the VirB4 ATPase, alone and bound to the core complex of a type IV secretion system. Proceedings of the National Academy of Sciences of the United States of America. 109: 11348-53. PMID 22745169 DOI: 10.1073/Pnas.1201428109 |
0.486 |
|
| 2012 |
Volkan E, Ford BA, Pinkner JS, Dodson KW, Henderson NS, Thanassi DG, Waksman G, Hultgren SJ. Domain activities of PapC usher reveal the mechanism of action of an Escherichia coli molecular machine. Proceedings of the National Academy of Sciences of the United States of America. 109: 9563-8. PMID 22645361 DOI: 10.1073/Pnas.1207085109 |
0.458 |
|
| 2012 |
Busch A, Waksman G. Chaperone-usher pathways: diversity and pilus assembly mechanism. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 1112-22. PMID 22411982 DOI: 10.1098/Rstb.2011.0206 |
0.377 |
|
| 2012 |
Waksman G. Bacterial secretion comes of age. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 1014-5. PMID 22411974 DOI: 10.1098/Rstb.2011.0200 |
0.3 |
|
| 2012 |
Allen WJ, Phan G, Waksman G. Pilus biogenesis at the outer membrane of Gram-negative bacterial pathogens. Current Opinion in Structural Biology. 22: 500-6. PMID 22402496 DOI: 10.1016/J.Sbi.2012.02.001 |
0.381 |
|
| 2012 |
Morrissey B, Leney AC, Toste Rêgo A, Phan G, Allen WJ, Verger D, Waksman G, Ashcroft AE, Radford SE. The role of chaperone-subunit usher domain interactions in the mechanism of bacterial pilus biogenesis revealed by ESI-MS. Molecular & Cellular Proteomics : McP. 11: M111.015289. PMID 22371487 DOI: 10.1074/Mcp.M111.015289 |
0.479 |
|
| 2011 |
Van Gerven N, Waksman G, Remaut H. Pili and flagella biology, structure, and biotechnological applications. Progress in Molecular Biology and Translational Science. 103: 21-72. PMID 21999994 DOI: 10.1016/B978-0-12-415906-8.00005-4 |
0.401 |
|
| 2011 |
Leney AC, Phan G, Allen W, Verger D, Waksman G, Radford SE, Ashcroft AE. Second order rate constants of donor-strand exchange reveal individual amino acid residues important in determining the subunit specificity of pilus biogenesis. Journal of the American Society For Mass Spectrometry. 22: 1214-23. PMID 21953104 DOI: 10.1007/S13361-011-0146-4 |
0.35 |
|
| 2011 |
Meng G, Spahich N, Kenjale R, Waksman G, St Geme JW. Crystal structure of the Haemophilus influenzae Hap adhesin reveals an intercellular oligomerization mechanism for bacterial aggregation. The Embo Journal. 30: 3864-74. PMID 21841773 DOI: 10.1038/Emboj.2011.279 |
0.429 |
|
| 2011 |
Chudasama V, Smith ME, Schumacher FF, Papaioannou D, Waksman G, Baker JR, Caddick S. Bromopyridazinedione-mediated protein and peptide bioconjugation. Chemical Communications (Cambridge, England). 47: 8781-3. PMID 21738916 DOI: 10.1039/C1Cc12807H |
0.313 |
|
| 2011 |
Jia H, Korolev S, Niedziela-Majka A, Maluf NK, Gauss GH, Myong S, Ha T, Waksman G, Lohman TM. Rotations of the 2B sub-domain of E. coli UvrD helicase/translocase coupled to nucleotide and DNA binding. Journal of Molecular Biology. 411: 633-48. PMID 21704638 DOI: 10.1016/J.Jmb.2011.06.019 |
0.368 |
|
| 2011 |
Phan G, Remaut H, Wang T, Allen WJ, Pirker KF, Lebedev A, Henderson NS, Geibel S, Volkan E, Yan J, Kunze MB, Pinkner JS, Ford B, Kay CW, Li H, ... ... Waksman G, et al. Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature. 474: 49-53. PMID 21637253 DOI: 10.1038/Nature10109 |
0.511 |
|
| 2011 |
Geibel S, Waksman G. Crystallography and electron microscopy of chaperone/usher pilus systems. Advances in Experimental Medicine and Biology. 715: 159-74. PMID 21557063 DOI: 10.1007/978-94-007-0940-9_10 |
0.402 |
|
| 2011 |
Banta LM, Kerr JE, Cascales E, Giuliano ME, Bailey ME, McKay C, Chandran V, Waksman G, Christie PJ. An Agrobacterium VirB10 mutation conferring a type IV secretion system gating defect. Journal of Bacteriology. 193: 2566-74. PMID 21421757 DOI: 10.1128/Jb.00038-11 |
0.357 |
|
| 2011 |
Terradot L, Waksman G. Architecture of the Helicobacter pylori Cag-type IV secretion system. The Febs Journal. 278: 1213-22. PMID 21352491 DOI: 10.1111/J.1742-4658.2011.08037.X |
0.382 |
|
| 2011 |
Cai X, Wang R, Filloux A, Waksman G, Meng G. Structural and functional characterization of Pseudomonas aeruginosa CupB chaperones. Plos One. 6: e16583. PMID 21304995 DOI: 10.1371/Journal.Pone.0016583 |
0.391 |
|
| 2011 |
Durand E, Waksman G, Receveur-Brechot V. Structural insights into the membrane-extracted dimeric form of the ATPase TraB from the Escherichia coli pKM101 conjugation system. Bmc Structural Biology. 11: 4. PMID 21266026 DOI: 10.1186/1472-6807-11-4 |
0.405 |
|
| 2011 |
Phan G, Remaut H, Allen W, Geibel S, Lebedev A, Henderson N, Thanassi D, Waksman G. Crystal structure of the usher:chaperone:adhesin subunit complex – insights into pilus assembly mechanism Acta Crystallographica Section a Foundations of Crystallography. 67: C24-C24. DOI: 10.1107/S0108767311099533 |
0.377 |
|
| 2011 |
Rothwell PJ, Allen WJ, Sisamakis E, Janissen R, Kalinin S, Felekyan S, Widengren J, Waksman G, Seidel CA. dNTP-Dependent Conformational Transitions in the Fingers Subdomain of Klentaq1 Biophysical Journal. 100: 376a. DOI: 10.1016/J.Bpj.2010.12.2238 |
0.336 |
|
| 2010 |
Wallden K, Rivera-Calzada A, Waksman G. Type IV secretion systems: versatility and diversity in function. Cellular Microbiology. 12: 1203-12. PMID 20642798 DOI: 10.1111/J.1462-5822.2010.01499.X |
0.413 |
|
| 2010 |
Waksman G, Fronzes R. Molecular architecture of bacterial type IV secretion systems. Trends in Biochemical Sciences. 35: 691-8. PMID 20621482 DOI: 10.1016/J.Tibs.2010.06.002 |
0.722 |
|
| 2010 |
Chorell E, Pinkner JS, Phan G, Edvinsson S, Buelens F, Remaut H, Waksman G, Hultgren SJ, Almqvist F. Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity. Journal of Medicinal Chemistry. 53: 5690-5. PMID 20586493 DOI: 10.1021/Jm100470T |
0.321 |
|
| 2010 |
Virdee S, Macmillan D, Waksman G. Semisynthetic Src SH2 domains demonstrate altered phosphopeptide specificity induced by incorporation of unnatural lysine derivatives. Chemistry & Biology. 17: 274-84. PMID 20338519 DOI: 10.1016/J.Chembiol.2010.01.015 |
0.421 |
|
| 2010 |
Durand E, Oomen C, Waksman G. Biochemical dissection of the ATPase TraB, the VirB4 homologue of the Escherichia coli pKM101 conjugation machinery. Journal of Bacteriology. 192: 2315-23. PMID 20172994 DOI: 10.1128/Jb.01384-09 |
0.452 |
|
| 2010 |
Rego AT, Fronzes R, Waksman G. SnapShot: Bacterial appendages II. Cell. 140: 294-294.e1. PMID 20141842 DOI: 10.1016/J.Cell.2010.01.006 |
0.671 |
|
| 2010 |
Ford B, Rêgo AT, Ragan TJ, Pinkner J, Dodson K, Driscoll PC, Hultgren S, Waksman G. Structural homology between the C-terminal domain of the PapC usher and its plug. Journal of Bacteriology. 192: 1824-31. PMID 20118254 DOI: 10.1128/Jb.01677-09 |
0.467 |
|
| 2010 |
Smith ME, Schumacher FF, Ryan CP, Tedaldi LM, Papaioannou D, Waksman G, Caddick S, Baker JR. Protein modification, bioconjugation, and disulfide bridging using bromomaleimides. Journal of the American Chemical Society. 132: 1960-5. PMID 20092331 DOI: 10.1021/Ja908610S |
0.358 |
|
| 2010 |
Rego AT, Fronzes R, Waksman G. SnapShot: Bacterial Appendages I. Cell. 140: 162-162.e1. PMID 20085708 DOI: 10.1016/j.cell.2009.12.047 |
0.63 |
|
| 2010 |
Rêgo AT, Chandran V, Waksman G. Two-step and one-step secretion mechanisms in Gram-negative bacteria: contrasting the type IV secretion system and the chaperone-usher pathway of pilus biogenesis. The Biochemical Journal. 425: 475-88. PMID 20070257 DOI: 10.1042/Bj20091518 |
0.361 |
|
| 2009 |
Allen WJ, Phan G, Waksman G. Structural biology of periplasmic chaperones. Advances in Protein Chemistry and Structural Biology. 78: 51-97. PMID 20663484 DOI: 10.1016/S1876-1623(08)78003-9 |
0.396 |
|
| 2009 |
Chandran V, Fronzes R, Duquerroy S, Cronin N, Navaza J, Waksman G. Structure of the outer membrane complex of a type IV secretion system. Nature. 462: 1011-5. PMID 19946264 DOI: 10.1038/Nature08588 |
0.706 |
|
| 2009 |
Waksman G, Hultgren SJ. Structural biology of the chaperone-usher pathway of pilus biogenesis. Nature Reviews. Microbiology. 7: 765-74. PMID 19820722 DOI: 10.1038/Nrmicro2220 |
0.308 |
|
| 2009 |
Fronzes R, Christie PJ, Waksman G. The structural biology of type IV secretion systems. Nature Reviews. Microbiology. 7: 703-14. PMID 19756009 DOI: 10.1038/Nrmicro2218 |
0.74 |
|
| 2009 |
Kenjale R, Meng G, Fink DL, Juehne T, Ohashi T, Erickson HP, Waksman G, St Geme JW. Structural determinants of autoproteolysis of the Haemophilus influenzae Hap autotransporter. Infection and Immunity. 77: 4704-13. PMID 19687208 DOI: 10.1128/Iai.00598-09 |
0.379 |
|
| 2009 |
Durand E, Verger D, Rêgo AT, Chandran V, Meng G, Fronzes R, Waksman G. Structural biology of bacterial secretion systems in gram-negative pathogens--potential for new drug targets. Infectious Disorders Drug Targets. 9: 518-47. PMID 19594425 DOI: 10.2174/187152609789105722 |
0.7 |
|
| 2009 |
Radin JN, Grass SA, Meng G, Cotter SE, Waksman G, St Geme JW. Structural basis for the differential binding affinities of the HsfBD1 and HsfBD2 domains in the Haemophilus influenzae Hsf adhesin. Journal of Bacteriology. 191: 5068-75. PMID 19525352 DOI: 10.1128/Jb.00395-09 |
0.399 |
|
| 2009 |
Waksman G. Going round in circles: the structural biology of type III secretion systems. Nature Structural & Molecular Biology. 16: 459-60. PMID 19421157 DOI: 10.1038/Nsmb0509-459 |
0.394 |
|
| 2009 |
Meng G, Fronzes R, Chandran V, Remaut H, Waksman G. Protein oligomerization in the bacterial outer membrane (Review). Molecular Membrane Biology. 26: 136-45. PMID 19225986 DOI: 10.1080/09687680802712422 |
0.702 |
|
| 2009 |
Fronzes R, Schäfer E, Wang L, Saibil HR, Orlova EV, Waksman G. Structure of a type IV secretion system core complex. Science (New York, N.Y.). 323: 266-8. PMID 19131631 DOI: 10.1126/Science.1166101 |
0.72 |
|
| 2009 |
Jakubowski SJ, Kerr JE, Garza I, Krishnamoorthy V, Bayliss R, Waksman G, Christie PJ. Agrobacterium VirB10 domain requirements for type IV secretion and T pilus biogenesis. Molecular Microbiology. 71: 779-94. PMID 19054325 DOI: 10.1111/J.1365-2958.2008.06565.X |
0.39 |
|
| 2009 |
Fronzes R, Waksman G. Structure and assembly of a bacterial type IV secretion core complex Acta Crystallographica Section a Foundations of Crystallography. 65: s22-s22. DOI: 10.1107/S0108767309099620 |
0.71 |
|
| 2008 |
Verger D, Rose RJ, Paci E, Costakes G, Daviter T, Hultgren S, Remaut H, Ashcroft AE, Radford SE, Waksman G. Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF. Structure (London, England : 1993). 16: 1724-31. PMID 19000824 DOI: 10.1016/J.Str.2008.08.012 |
0.338 |
|
| 2008 |
Meng G, St Geme JW, Waksman G. Repetitive architecture of the Haemophilus influenzae Hia trimeric autotransporter. Journal of Molecular Biology. 384: 824-36. PMID 18948113 DOI: 10.1016/J.Jmb.2008.09.085 |
0.457 |
|
| 2008 |
Rose RJ, Verger D, Daviter T, Remaut H, Paci E, Waksman G, Ashcroft AE, Radford SE. Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 105: 12873-8. PMID 18728178 DOI: 10.1073/Pnas.0802177105 |
0.343 |
|
| 2008 |
Backert S, Fronzes R, Waksman G. VirB2 and VirB5 proteins: specialized adhesins in bacterial type-IV secretion systems? Trends in Microbiology. 16: 409-13. PMID 18706815 DOI: 10.1016/J.Tim.2008.07.001 |
0.686 |
|
| 2008 |
Fronzes R, Remaut H, Waksman G. Architectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria. The Embo Journal. 27: 2271-80. PMID 18668121 DOI: 10.1038/Emboj.2008.155 |
0.713 |
|
| 2008 |
Bagnéris C, Ageichik AV, Cronin N, Wallace B, Collins M, Boshoff C, Waksman G, Barrett T. Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome. Molecular Cell. 30: 620-31. PMID 18538660 DOI: 10.1016/J.Molcel.2008.04.029 |
0.346 |
|
| 2008 |
Remaut H, Tang C, Henderson NS, Pinkner JS, Wang T, Hultgren SJ, Thanassi DG, Waksman G, Li H. Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell. 133: 640-52. PMID 18485872 DOI: 10.1016/J.Cell.2008.03.033 |
0.458 |
|
| 2008 |
Salih O, Remaut H, Waksman G, Orlova EV. Structural analysis of the Saf pilus by electron microscopy and image processing. Journal of Molecular Biology. 379: 174-87. PMID 18448124 DOI: 10.1016/J.Jmb.2008.03.056 |
0.387 |
|
| 2008 |
De Fabritiis G, Geroult S, Coveney PV, Waksman G. Insights from the energetics of water binding at the domain-ligand interface of the Src SH2 domain. Proteins. 72: 1290-7. PMID 18384045 DOI: 10.1002/Prot.22027 |
0.424 |
|
| 2008 |
Rose RJ, Welsh TS, Waksman G, Ashcroft AE, Radford SE, Paci E. Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics. Journal of Molecular Biology. 375: 908-19. PMID 18054959 DOI: 10.1016/J.Jmb.2007.10.077 |
0.377 |
|
| 2007 |
Fowler PW, Geroult S, Jha S, Waksman G, Coveney PV. Rapid, Accurate, and Precise Calculation of Relative Binding Affinities for the SH2 Domain Using a Computational Grid. Journal of Chemical Theory and Computation. 3: 1193-202. PMID 26627438 DOI: 10.1021/Ct6003017 |
0.337 |
|
| 2007 |
Hare S, Fischer W, Williams R, Terradot L, Bayliss R, Haas R, Waksman G. Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase. The Embo Journal. 26: 4926-34. PMID 17972918 DOI: 10.1038/Sj.Emboj.7601904 |
0.461 |
|
| 2007 |
Geroult S, Hooda M, Virdee S, Waksman G. Prediction of solvation sites at the interface of Src SH2 domain complexes using molecular dynamics simulations. Chemical Biology & Drug Design. 70: 87-99. PMID 17683370 DOI: 10.1111/J.1747-0285.2007.00545.X |
0.422 |
|
| 2007 |
Rothwell PJ, Waksman G. A pre-equilibrium before nucleotide binding limits fingers subdomain closure by Klentaq1. The Journal of Biological Chemistry. 282: 28884-92. PMID 17640877 DOI: 10.1074/Jbc.M704824200 |
0.324 |
|
| 2007 |
Verger D, Bullitt E, Hultgren SJ, Waksman G. Crystal structure of the P pilus rod subunit PapA. Plos Pathogens. 3: e73. PMID 17511517 DOI: 10.1371/Journal.Ppat.0030073 |
0.406 |
|
| 2007 |
Bayliss R, Harris R, Coutte L, Monier A, Fronzes R, Christie PJ, Driscoll PC, Waksman G. NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system. Proceedings of the National Academy of Sciences of the United States of America. 104: 1673-8. PMID 17244707 DOI: 10.1073/Pnas.0609535104 |
0.737 |
|
| 2006 |
Pinkner JS, Remaut H, Buelens F, Miller E, Aberg V, Pemberton N, Hedenström M, Larsson A, Seed P, Waksman G, Hultgren SJ, Almqvist F. Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 103: 17897-902. PMID 17098869 DOI: 10.1073/Pnas.0606795103 |
0.41 |
|
| 2006 |
Verger D, Miller E, Remaut H, Waksman G, Hultgren S. Molecular mechanism of P pilus termination in uropathogenic Escherichia coli. Embo Reports. 7: 1228-32. PMID 17082819 DOI: 10.1038/Sj.Embor.7400833 |
0.361 |
|
| 2006 |
Remaut H, Waksman G. Protein-protein interaction through beta-strand addition. Trends in Biochemical Sciences. 31: 436-44. PMID 16828554 DOI: 10.1016/J.Tibs.2006.06.007 |
0.344 |
|
| 2006 |
Remaut H, Rose RJ, Hannan TJ, Hultgren SJ, Radford SE, Ashcroft AE, Waksman G. Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Molecular Cell. 22: 831-42. PMID 16793551 DOI: 10.1016/J.Molcel.2006.05.033 |
0.35 |
|
| 2006 |
Hare S, Bayliss R, Baron C, Waksman G. A large domain swap in the VirB11 ATPase of Brucella suis leaves the hexameric assembly intact. Journal of Molecular Biology. 360: 56-66. PMID 16730027 DOI: 10.1016/J.Jmb.2006.04.060 |
0.452 |
|
| 2006 |
Meng G, Surana NK, St Geme JW, Waksman G. Structure of the outer membrane translocator domain of the Haemophilus influenzae Hia trimeric autotransporter. The Embo Journal. 25: 2297-304. PMID 16688217 DOI: 10.1038/Sj.Emboj.7601132 |
0.44 |
|
| 2006 |
Paschos A, Patey G, Sivanesan D, Gao C, Bayliss R, Waksman G, O'callaghan D, Baron C. Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity. Proceedings of the National Academy of Sciences of the United States of America. 103: 7252-7. PMID 16648257 DOI: 10.1073/Pnas.0600862103 |
0.414 |
|
| 2006 |
Harris R, Bayliss R, Waksman G, Driscoll PC. Resonance assignments of the complex between TraN and the C-terminal domain of TraO from the conjugative plasmid pKM101. Journal of Biomolecular Nmr. 36: 31. PMID 16601857 DOI: 10.1007/S10858-006-0015-9 |
0.354 |
|
| 2006 |
Geroult S, Virdee S, Waksman G. The role of water in computational and experimental derivation of binding thermodynamics in SH2 domains. Chemical Biology & Drug Design. 67: 38-45. PMID 16492147 DOI: 10.1111/J.1747-0285.2005.00315.X |
0.355 |
|
| 2005 |
Lubman OY, Kopan R, Waksman G, Korolev S. The crystal structure of a partial mouse Notch-1 ankyrin domain: repeats 4 through 7 preserve an ankyrin fold. Protein Science : a Publication of the Protein Society. 14: 1274-81. PMID 15802643 DOI: 10.1110/Ps.041184105 |
0.81 |
|
| 2005 |
Terradot L, Bayliss R, Oomen C, Leonard GA, Baron C, Waksman G. Structures of two core subunits of the bacterial type IV secretion system, VirB8 from Brucella suis and ComB10 from Helicobacter pylori. Proceedings of the National Academy of Sciences of the United States of America. 102: 4596-601. PMID 15764702 DOI: 10.1073/Pnas.0408927102 |
0.458 |
|
| 2005 |
Terradot L, Bayliss R, Oomen C, Leonard G, Waksman G. Structural biology of Type IV secretion system Acta Crystallographica Section a Foundations of Crystallography. 61: c239-c240. DOI: 10.1107/S0108767305089798 |
0.356 |
|
| 2004 |
Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, Mathews FS, Di Cera E. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. The Journal of Biological Chemistry. 279: 39824-8. PMID 15252033 DOI: 10.1074/Jbc.M407272200 |
0.4 |
|
| 2004 |
Savvides SN, Raghunathan S, Fütterer K, Kozlov AG, Lohman TM, Waksman G. The C-terminal domain of full-length E. coli SSB is disordered even when bound to DNA. Protein Science : a Publication of the Protein Society. 13: 1942-7. PMID 15169953 DOI: 10.1110/Ps.04661904 |
0.452 |
|
| 2004 |
Terradot L, Durnell N, Li M, Li M, Ory J, Labigne A, Legrain P, Colland F, Waksman G. Biochemical characterization of protein complexes from the Helicobacter pylori protein interaction map: strategies for complex formation and evidence for novel interactions within type IV secretion systems. Molecular & Cellular Proteomics : McP. 3: 809-19. PMID 15133060 DOI: 10.1074/Mcp.M400048-Mcp200 |
0.36 |
|
| 2004 |
Remaut H, Waksman G. Structural biology of bacterial pathogenesis Current Opinion in Structural Biology. 14: 161-170. PMID 15093830 DOI: 10.1016/J.Sbi.2004.03.004 |
0.432 |
|
| 2004 |
Waksman G, Kuriyan J. Structure and specificity of the SH2 domain. Cell. 116: S45-48, 3 p followin. PMID 15055581 DOI: 10.1016/S0092-8674(04)00043-1 |
0.617 |
|
| 2004 |
Yeo HJ, Cotter SE, Laarmann S, Juehne T, St. Geme JW, Waksman G. Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter Embo Journal. 23: 1245-1256. PMID 15029242 DOI: 10.1038/Sj.Emboj.7600142 |
0.446 |
|
| 2004 |
Yeo HJ, Waksman G. Unveiling Molecular Scaffolds of the Type IV Secretion System Journal of Bacteriology. 186: 1919-1926. PMID 15028675 DOI: 10.1128/Jb.186.7.1919-1926.2004 |
0.354 |
|
| 2004 |
Waksman G, Kumaran S, Lubman O. SH2 domains: role, structure and implications for molecular medicine. Expert Reviews in Molecular Medicine. 6: 1-18. PMID 14987415 DOI: 10.1017/S1462399404007331 |
0.806 |
|
| 2004 |
Waksman G, Kumaran S, Lubman O. SH2 domains: role, structure and implications for molecular medicine. Expert Reviews in Molecular Medicine. 6: 1-18. PMID 14987415 DOI: 10.1017/S1462399404007331 |
0.806 |
|
| 2003 |
Yeo HJ, Yuan Q, Beck MR, Baron C, Waksman G. Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101. Proceedings of the National Academy of Sciences of the United States of America. 100: 15947-52. PMID 14673074 DOI: 10.1073/Pnas.2535211100 |
0.445 |
|
| 2003 |
Kumaran S, Grucza RA, Waksman G. The tandem Src homology 2 domain of the Syk kinase: a molecular device that adapts to interphosphotyrosine distances. Proceedings of the National Academy of Sciences of the United States of America. 100: 14828-33. PMID 14657388 DOI: 10.1073/Pnas.2432867100 |
0.617 |
|
| 2003 |
Savvides SN, Yeo HJ, Beck MR, Blaesing F, Lurz R, Lanka E, Buhrdorf R, Fischer W, Haas R, Waksman G. VirB11 ATPases are dynamic hexameric assemblies: new insights into bacterial type IV secretion. The Embo Journal. 22: 1969-80. PMID 12727865 DOI: 10.1093/Emboj/Cdg223 |
0.471 |
|
| 2003 |
Lubman OY, Waksman G. Structural and thermodynamic basis for the interaction of the Src SH2 domain with the activated form of the PDGF beta-receptor. Journal of Molecular Biology. 328: 655-68. PMID 12706723 DOI: 10.1016/S0022-2836(03)00344-9 |
0.8 |
|
| 2002 |
Bradshaw JM, Waksman G. Molecular recognition by SH2 domains. Advances in Protein Chemistry. 61: 161-210. PMID 12461824 DOI: 10.1016/S0065-3233(02)61005-8 |
0.332 |
|
| 2002 |
Cheng W, Brendza KM, Gauss GH, Korolev S, Waksman G, Lohman TM. The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity. Proceedings of the National Academy of Sciences of the United States of America. 99: 16006-11. PMID 12441398 DOI: 10.1073/Pnas.242479399 |
0.337 |
|
| 2002 |
Sauer FG, Pinkner JS, Waksman G, Hultgren SJ. Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell. 111: 543-51. PMID 12437927 DOI: 10.1016/S0092-8674(02)01050-4 |
0.326 |
|
| 2002 |
Pineda AO, Savvides SN, Waksman G, Di Cera E. Crystal structure of the anticoagulant slow form of thrombin. The Journal of Biological Chemistry. 277: 40177-80. PMID 12205081 DOI: 10.1074/Jbc.C200465200 |
0.386 |
|
| 2002 |
Hung CS, Bouckaert J, Hung D, Pinkner J, Widberg C, DeFusco A, Auguste CG, Strouse R, Langermann S, Waksman G, Hultgren SJ. Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Molecular Microbiology. 44: 903-15. PMID 12010488 DOI: 10.1046/J.1365-2958.2002.02915.X |
0.347 |
|
| 2002 |
Schröder G, Krause S, Zechner EL, Traxler B, Yeo HJ, Lurz R, Waksman G, Lanka E. TraG-like proteins of DNA transfer systems and of the Helicobacter pylori type IV secretion system: inner membrane gate for exported substrates? Journal of Bacteriology. 184: 2767-79. PMID 11976307 DOI: 10.1128/Jb.184.10.2767-2779.2002 |
0.418 |
|
| 2002 |
Yeo HJ, Ziegelin G, Korolev S, Calendar R, Lanka E, Waksman G. Phage P4 origin-binding domain structure reveals a mechanism for regulation of DNA-binding activity by homo- and heterodimerization of winged helix proteins. Molecular Microbiology. 43: 855-67. PMID 11929537 DOI: 10.1046/J.1365-2958.2002.02796.X |
0.449 |
|
| 2002 |
Lubman OY, Waksman G. Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface. Journal of Molecular Biology. 316: 291-304. PMID 11851339 DOI: 10.1006/Jmbi.2001.5362 |
0.79 |
|
| 2002 |
Davidson JP, Lubman O, Rose T, Waksman G, Martin SF. Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding. Journal of the American Chemical Society. 124: 205-15. PMID 11782172 DOI: 10.1021/Ja011746F |
0.795 |
|
| 2002 |
Yeo H, Savvides S, Lanka E, Waksman G. Crystal structure of the hexameric traffic ATPase of theHelicobacter pyloritype IV secretion system: insights into function and mode of action Acta Crystallographica Section a Foundations of Crystallography. 58: c303-c303. DOI: 10.1107/S0108767302097088 |
0.322 |
|
| 2001 |
Ricard CS, Jakubowski JM, Verbsky JW, Barbieri MA, Lewis WM, Fernandez GE, Vogel M, Tsou C, Prasad V, Stahl PD, Waksman G, Cheney CM. Drosophila rab GDI mutants disrupt development but have normal Rab membrane extraction. Genesis (New York, N.Y. : 2000). 31: 17-29. PMID 11668674 DOI: 10.1002/Gene.10000 |
0.393 |
|
| 2001 |
Farazi TA, Manchester JK, Waksman G, Gordon JI. Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis. Biochemistry. 40: 9177-86. PMID 11478885 DOI: 10.1021/Bi0107997 |
0.368 |
|
| 2001 |
Dodson KW, Pinkner JS, Rose T, Magnusson G, Hultgren SJ, Waksman G. Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor. Cell. 105: 733-43. PMID 11440716 DOI: 10.1016/S0092-8674(01)00388-9 |
0.399 |
|
| 2001 |
Farazi TA, Waksman G, Gordon JI. Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. Biochemistry. 40: 6335-43. PMID 11371195 DOI: 10.1021/Bi0101401 |
0.407 |
|
| 2001 |
Li Y, Waksman G. Crystal structures of a ddATP-, ddTTP-, ddCTP-, and ddGTP-trapped ternary complex of Klentaq1: Insights into nucleotide incorporation and selectivity Protein Science. 10: 1225-1233. PMID 11369861 DOI: 10.1110/Ps.250101 |
0.384 |
|
| 2001 |
Fütterer K, Murray CL, Bhatnagar RS, Gokel GW, Gordon JI, Waksman G. Crystallographic phasing of myristoyl-CoA-protein N-myristoyltransferase using an iodinated analog of myristoyl-CoA. Acta Crystallographica. Section D, Biological Crystallography. 57: 393-400. PMID 11223516 DOI: 10.1107/S090744490100052X |
0.365 |
|
| 2001 |
Bhatnagar RS, Ashrafi K, Fütterer K, Waksman G, Gordon JI. 9 Biology and enzymology of protein N-myristoylation Enzymes. 21: 241-290. DOI: 10.1016/S1874-6047(01)80022-6 |
0.35 |
|
| 2000 |
Yeo HJ, Savvides SN, Herr AB, Lanka E, Waksman G. Crystal structure of the hexameric traffic ATPase of the Helicobacter pylori type IV secretion system Molecular Cell. 6: 1461-1472. PMID 11163218 DOI: 10.1016/S1097-2765(00)00142-8 |
0.695 |
|
| 2000 |
Yu K, Herr AB, Waksman G, Ornitz DM. Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome Proceedings of the National Academy of Sciences of the United States of America. 97: 14536-14541. PMID 11121055 DOI: 10.1073/Pnas.97.26.14536 |
0.603 |
|
| 2000 |
Sauer FG, Barnhart M, Choudhury D, Knight SD, Waksman G, Hultgren SJ. Chaperone-assisted pilus assembly and bacterial attachment. Current Opinion in Structural Biology. 10: 548-56. PMID 11042452 DOI: 10.1016/S0959-440X(00)00129-9 |
0.381 |
|
| 2000 |
Grucza RA, Bradshaw JM, Mitaxov V, Waksman G. Role of electrostatic interactions in SH2 domain recognition: salt-dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the Src kinase. Biochemistry. 39: 10072-81. PMID 10955995 DOI: 10.1021/Bi000891N |
0.63 |
|
| 2000 |
Raghunathan S, Kozlov AG, Lohman TM, Waksman G. Structure of the DNA binding domain of E. coli SSB bound to ssDNA. Nature Structural Biology. 7: 648-52. PMID 10932248 DOI: 10.1038/77943 |
0.386 |
|
| 2000 |
Bradshaw JM, Mitaxov V, Waksman G. Mutational investigation of the specificity determining region of the Src SH2 domain. Journal of Molecular Biology. 299: 521-35. PMID 10860756 DOI: 10.1006/Jmbi.2000.3765 |
0.423 |
|
| 2000 |
Barnhart MM, Pinkner JS, Soto GE, Sauer FG, Langermann S, Waksman G, Frieden C, Hultgren SJ. PapD-like chaperones provide the missing information for folding of pilin proteins. Proceedings of the National Academy of Sciences of the United States of America. 97: 7709-14. PMID 10859353 DOI: 10.1073/Pnas.130183897 |
0.416 |
|
| 1999 |
Bhatnagar RS, Fütterer K, Waksman G, Gordon JI. The structure of myristoyl-CoA:protein N-myristoyltransferase. Biochimica Et Biophysica Acta. 1441: 162-72. PMID 10570244 DOI: 10.1016/S1388-1981(99)00155-9 |
0.361 |
|
| 1999 |
Bradshaw JM, Mitaxov V, Waksman G. Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase. Journal of Molecular Biology. 293: 971-85. PMID 10543978 DOI: 10.1006/Jmbi.1999.3190 |
0.426 |
|
| 1999 |
Lu D, Fütterer K, Korolev S, Zheng X, Tan K, Waksman G, Sadler JE. Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide Journal of Molecular Biology. 292: 361-373. PMID 10493881 DOI: 10.1006/Jmbi.1999.3089 |
0.401 |
|
| 1999 |
Li Y, Mitaxov V, Waksman G. Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation Proceedings of the National Academy of Sciences of the United States of America. 96: 9491-9496. PMID 10449720 DOI: 10.1073/Pnas.96.17.9491 |
0.31 |
|
| 1999 |
Sauer FG, Fütterer K, Pinkner JS, Dodson KW, Hultgren SJ, Waksman G. Structural basis of chaperone function and pilus biogenesis. Science (New York, N.Y.). 285: 1058-61. PMID 10446050 DOI: 10.1126/Science.285.5430.1058 |
0.433 |
|
| 1999 |
Grucza RA, Bradshaw JM, Fütterer K, Waksman G. SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships. Medicinal Research Reviews. 19: 273-93. PMID 10398925 DOI: 10.1002/(Sici)1098-1128(199907)19:4<273::Aid-Med2>3.0.Co;2-G |
0.625 |
|
| 1999 |
Grucza RA, Fütterer K, Chan AC, Waksman G. Thermodynamic study of the binding of the tandem-SH2 domain of the Syk kinase to a dually phosphorylated ITAM peptide: evidence for two conformers. Biochemistry. 38: 5024-33. PMID 10213605 DOI: 10.1021/Bi9829938 |
0.61 |
|
| 1999 |
Guinto ER, Caccia S, Rose T, Fütterer K, Waksman G, Di Cera E. Unexpected crucial role of residue 225 in serine proteases. Proceedings of the National Academy of Sciences of the United States of America. 96: 1852-7. PMID 10051558 DOI: 10.1073/Pnas.96.5.1852 |
0.385 |
|
| 1998 |
Li Y, Korolev S, Waksman G. Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: Structural basis for nucleotide incorporation Embo Journal. 17: 7514-7525. PMID 9857206 DOI: 10.1093/Emboj/17.24.7514 |
0.412 |
|
| 1998 |
Bhatnagar RS, Fütterer K, Farazi TA, Korolev S, Murray CL, Jackson-Machelski E, Gokel GW, Gordon JI, Waksman G. Structure of N-myristoyltransferase with bound myristoylCoA and peptide substrate analogs. Nature Structural Biology. 5: 1091-7. PMID 9846880 DOI: 10.1038/4202 |
0.369 |
|
| 1998 |
Chung E, Henriques D, Renzoni D, Zvelebil M, Bradshaw JM, Waksman G, Robinson CV, Ladbury JE. Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides. Structure (London, England : 1993). 6: 1141-51. PMID 9753693 DOI: 10.1016/S0969-2126(98)00115-4 |
0.409 |
|
| 1998 |
Wang K, Gross A, Waksman G, Korsmeyer SJ. Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing Molecular and Cellular Biology. 18: 6083-6089. PMID 9742125 DOI: 10.1128/Mcb.18.10.6083 |
0.352 |
|
| 1998 |
Fütterer K, Wong J, Grucza RA, Chan AC, Waksman G. Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide. Journal of Molecular Biology. 281: 523-37. PMID 9698567 DOI: 10.1006/Jmbi.1998.1964 |
0.662 |
|
| 1998 |
Waksman G, Herr AB. New insights into heparin-induced FGF oligomerization Nature Structural Biology. 5: 527-530. PMID 9665161 DOI: 10.1038/778 |
0.629 |
|
| 1998 |
Bradshaw JM, Grucza RA, Ladbury JE, Waksman G. Probing the "two-pronged plug two-holed socket" model for the mechanism of binding of the Src SH2 domain to phosphotyrosyl peptides: a thermodynamic study. Biochemistry. 37: 9083-90. PMID 9636054 DOI: 10.1021/Bi973147K |
0.62 |
|
| 1998 |
Li Y, Kong Y, Korolev S, Waksman G. Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates Protein Science. 7: 1116-1123. PMID 9605316 DOI: 10.1002/Pro.5560070505 |
0.394 |
|
| 1998 |
Korolev S, Yao N, Lohman TM, Weber PC, Waksman G. Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Science : a Publication of the Protein Society. 7: 605-10. PMID 9541392 DOI: 10.1002/Pro.5560070309 |
0.306 |
|
| 1997 |
Zha J, Harada H, Osipov K, Jockel J, Waksman G, Korsmeyer SJ. BH3 domain of BAD is required for heterodimerization with BCL-X(L) and pro-apoptotic activity Journal of Biological Chemistry. 272: 24101-24104. PMID 9305851 DOI: 10.1074/Jbc.272.39.24101 |
0.333 |
|
| 1997 |
Korolev S, Hsieh J, Gauss GH, Lohman TM, Waksman G. Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP. Cell. 90: 635-47. PMID 9288744 DOI: 10.1016/S0092-8674(00)80525-5 |
0.413 |
|
| 1997 |
Herr AB, Ornitz DM, Sasisekharan R, Venkataraman G, Waksman G. Heparin-induced self-association of fibroblast growth factor-2: Evidence for two oligomerization processes Journal of Biological Chemistry. 272: 16382-16389. PMID 9195945 DOI: 10.1074/Jbc.272.26.16382 |
0.609 |
|
| 1997 |
Raghunathan S, Ricard CS, Lohman TM, Waksman G. Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 94: 6652-7. PMID 9192620 DOI: 10.1073/Pnas.94.13.6652 |
0.404 |
|
| 1996 |
Réty S, Fütterer K, Grucza RA, Munoz CM, Frazier WA, Waksman G. pH-Dependent self-association of the Src homology 2 (SH2) domain of the Src homologous and collagen-like (SHC) protein. Protein Science : a Publication of the Protein Society. 5: 405-13. PMID 8868476 DOI: 10.1002/Pro.5560050301 |
0.669 |
|
| 1996 |
Venkataraman G, Sasisekharan V, Herr AB, Ornitz DM, Waksman G, Cooney CL, Langer R, Sasisekharan R. Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation Proceedings of the National Academy of Sciences of the United States of America. 93: 845-850. PMID 8570646 DOI: 10.1073/Pnas.93.2.845 |
0.613 |
|
| 1996 |
Korolev S, Nayal M, Barnes WM, Di Cera E, Waksman G. Crystal structure of Klenow-analogous fragment ofThermus aquaticusDNA polymerase I at 2.5 Å resolution Acta Crystallographica Section a Foundations of Crystallography. 52: C156-C156. DOI: 10.1107/S0108767396092987 |
0.322 |
|
| 1996 |
Fütterer K, Réty S, Grucza RA, Waksman G. Crystal structure of the SH2 domain of the protein SHC: pH-dependent self-association Acta Crystallographica Section a Foundations of Crystallography. 52: C187-C187. DOI: 10.1107/S0108767396091830 |
0.617 |
|
| 1996 |
Herr AB, Ornitz DM, Waksman G. Co-crystal structures of basic fibroblast growth factor complexed with di- and trisaccharide heparin analogs Acta Crystallographica Section a Foundations of Crystallography. 52: C197-C198. DOI: 10.1107/S0108767396091441 |
0.618 |
|
| 1995 |
Korolev S, Nayal M, Barnes WM, Di Cera E, Waksman G. Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-Å resolution: Structural basis for thermostability Proceedings of the National Academy of Sciences of the United States of America. 92: 9264-9268. PMID 7568114 DOI: 10.1073/Pnas.92.20.9264 |
0.443 |
|
| 1995 |
Ornitz DM, Herr AB, Nilsson M, Westman J, Svahn CM, Waksman G. FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides Science. 268: 432-436. PMID 7536345 DOI: 10.1126/Science.7536345 |
0.611 |
|
| 1994 |
Waksman G, Krishna TSR, Williams CH, Kuriyan J. Crystal structure of Escherichia coli thioredoxin reductase refined at 2 Å resolution: Implications for a large conformational change during catalysis Journal of Molecular Biology. 236: 800-816. PMID 8114095 DOI: 10.2210/Pdb1Tde/Pdb |
0.55 |
|
| 1994 |
Waksman G. Crystal structure of the phosphotyrosine recognition domain SH2 of the Src oncogene product complexed with tyrosine-phosphorylated peptides Cellular and Molecular Biology. 40: 611-618. PMID 7526915 |
0.316 |
|
| 1994 |
Waksman G, Krishna TSR, Williams CH, Kuriyan J. Crystal Structure of Escherichia coli Thioredoxin Reductase Refined at 2 Å Resolution Journal of Molecular Biology. 236: 800-816. DOI: 10.1006/Jmbi.1994.1190 |
0.548 |
|
| 1994 |
Waksman G. Structural basis for peptide-binding specificity of SH2 domains Bulletin De L'Institut Pasteur. 92: 19-25. |
0.31 |
|
| 1993 |
Martin JL, Waksman G, Bardwell JCA, Beckwith J, Kuriyan J. Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo Journal of Molecular Biology. 230: 1097-1100. PMID 8478925 DOI: 10.1006/Jmbi.1993.1226 |
0.487 |
|
| 1993 |
Waksman G, Shoelson SE, Pant N, Cowburn D, Kuriyan J. Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell. 72: 779-90. PMID 7680960 DOI: 10.1016/0092-8674(93)90405-F |
0.727 |
|
| 1992 |
Waksman G, Kominos D, Robertson SC, Pant N, Baltimore D, Birge RB, Cowburn D, Hanafusa H, Mayer BJ, Overduin M, Resh MD, Rios CB, Silverman L, Kuriyan J. Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides Nature. 358: 646-653. PMID 1379696 DOI: 10.1038/358646A0 |
0.71 |
|
| Show low-probability matches. |