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Ao-Lin Hsu, Ph.D. - Publications

Affiliations: 
2000 University of Kentucky, Lexington, KY 
Area:
Biochemistry
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen TY, Wang FY, Lee PJ, Hsu AL, Ching TT. Mitochondrial S-adenosylmethionine deficiency induces mitochondrial unfolded protein response and extends lifespan in Caenorhabditis elegans. Aging Cell. e14103. PMID 38361361 DOI: 10.1111/acel.14103  0.552
2022 Lim CY, Lin HT, Kumsta C, Lu TC, Wang FY, Kang YH, Hansen M, Ching TT, Hsu AL. SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity. Autophagy. 1-17. PMID 35503435 DOI: 10.1080/15548627.2022.2068267  0.702
2020 Chen CC, Lim CY, Lee PJ, Hsu AL, Ching TT. S-adenosyl methionine synthetase SAMS-5 mediates dietary restriction-induced longevity in Caenorhabditis elegans. Plos One. 15: e0241455. PMID 33175851 DOI: 10.1371/journal.pone.0241455  0.577
2020 Sural S, Liang CY, Wang FY, Ching TT, Hsu AL. HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity. Science Advances. 6. PMID 33087356 DOI: 10.1126/sciadv.aaz4452  0.741
2020 Lombard DB, Kohler WJ, Guo AH, Gendron C, Han M, Ding W, Lyu Y, Ching TT, Wang FY, Chakraborty TS, Nikolovska-Coleska Z, Duan Y, Girke T, Hsu AL, Pletcher SD, et al. High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Science Advances. 6. PMID 33008901 DOI: 10.1126/sciadv.aaz7628  0.658
2020 Ching TT, Chen YC, Li G, Liu J, Xu XS, Hsu AL. Short-term enhancement of motor neuron synaptic exocytosis during early aging extends lifespan in . Experimental Biology and Medicine (Maywood, N.J.). 1535370220950639. PMID 32854519 DOI: 10.1177/1535370220950639  0.552
2020 Kuo CT, You GT, Jian YJ, Chen TS, Siao YC, Hsu AL, Ching TT. AMPK-mediated formation of stress granules is required for dietary restriction-induced longevity in Caenorhabditis elegans. Aging Cell. e13157. PMID 32432401 DOI: 10.1111/Acel.13157  0.614
2019 Sural S, Lu TC, Jung SA, Hsu AL. HSB-1 Inhibition and HSF-1 Overexpression Trigger Overlapping Transcriptional Changes to Promote Longevity in . G3 (Bethesda, Md.). PMID 30894454 DOI: 10.1534/g3.119.400044  0.771
2019 Li ST, Zhao HQ, Zhang P, Liang CY, Zhang YP, Hsu AL, Dong MQ. DAF-16 stabilizes the aging transcriptome and is activated in mid-aged Caenorhabditis elegans to cope with internal stress. Aging Cell. e12896. PMID 30773782 DOI: 10.1111/acel.12896  0.346
2015 Yuan Y, Hakimi P, Kao C, Kao A, Liu R, Janocha A, Boyd-Tressler A, Hang X, Alhoraibi H, Slater E, Xia K, Cao P, Shue Q, Ching TT, Hsu AL, et al. Reciprocal changes in phosphoenolpyruvate carboxykinase and pyruvate kinase with age are a determinant of aging in C. elegans. The Journal of Biological Chemistry. PMID 26631730 DOI: 10.1074/Jbc.M115.691766  0.59
2015 Horikawa M, Sural S, Hsu AL, Antebi A. Co-chaperone p23 regulates C. elegans Lifespan in Response to Temperature. Plos Genetics. 11: e1005023. PMID 25830239 DOI: 10.1371/journal.pgen.1005023  0.751
2014 Kumsta C, Ching TT, Nishimura M, Davis AE, Gelino S, Catan HH, Yu X, Chu CC, Ong B, Panowski SH, Baird N, Bodmer R, Hsu AL, Hansen M. Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. Aging Cell. 13: 419-30. PMID 24314125 DOI: 10.1111/Acel.12189  0.726
2012 Chiang WC, Tishkoff DX, Yang B, Wilson-Grady J, Yu X, Mazer T, Eckersdorff M, Gygi SP, Lombard DB, Hsu AL. C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress. Plos Genetics. 8: e1002948. PMID 23028355 DOI: 10.1371/Journal.Pgen.1002948  0.333
2012 Yuan Y, Kadiyala CS, Ching TT, Hakimi P, Saha S, Xu H, Yuan C, Mullangi V, Wang L, Fivenson E, Hanson RW, Ewing R, Hsu AL, Miyagi M, Feng Z. Enhanced energy metabolism contributes to the extended life span of calorie-restricted Caenorhabditis elegans. The Journal of Biological Chemistry. 287: 31414-26. PMID 22810224 DOI: 10.1074/Jbc.M112.377275  0.535
2012 Chiang WC, Ching TT, Lee HC, Mousigian C, Hsu AL. HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity. Cell. 148: 322-34. PMID 22265419 DOI: 10.1016/j.cell.2011.12.019  0.628
2011 Ching TT, Hsu AL. Solid plate-based dietary restriction in Caenorhabditis elegans. Journal of Visualized Experiments : Jove. PMID 21654629 DOI: 10.3791/2701  0.56
2011 Ching TT, Chiang WC, Chen CS, Hsu AL. Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity. Aging Cell. 10: 506-19. PMID 21348927 DOI: 10.1111/j.1474-9726.2011.00688.x  0.667
2010 Ching TT, Paal AB, Mehta A, Zhong L, Hsu AL. drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans. Aging Cell. 9: 545-57. PMID 20456299 DOI: 10.1111/j.1474-9726.2010.00580.x  0.626
2005 Hansen M, Hsu AL, Dillin A, Kenyon C. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. Plos Genetics. 1: 119-28. PMID 16103914 DOI: 10.1371/Journal.Pgen.0010017  0.736
2003 Hsu AL, Murphy CT, Kenyon C. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science (New York, N.Y.). 300: 1142-5. PMID 12750521 DOI: 10.1126/Science.1083701  0.682
2002 Dillin A, Hsu AL, Arantes-Oliveira N, Lehrer-Graiwer J, Hsin H, Fraser AG, Kamath RS, Ahringer J, Kenyon C. Rates of behavior and aging specified by mitochondrial function during development. Science (New York, N.Y.). 298: 2398-401. PMID 12471266 DOI: 10.1126/Science.1077780  0.636
2002 Garigan D, Hsu AL, Fraser AG, Kamath RS, Ahringer J, Kenyon C. Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics. 161: 1101-12. PMID 12136014  0.715
2002 Johnson AJ, Hsu AL, Lin HP, Song X, Chen CS. The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks. The Biochemical Journal. 366: 831-7. PMID 12076251 DOI: 10.1042/Bj20020279  0.564
2001 Ching TT, Hsu AL, Johnson AJ, Chen CS. Phosphoinositide 3-kinase facilitates antigen-stimulated Ca(2+) influx in RBL-2H3 mast cells via a phosphatidylinositol 3,4,5-trisphosphate-sensitive Ca(2+) entry mechanism. The Journal of Biological Chemistry. 276: 14814-20. PMID 11278575 DOI: 10.1074/jbc.M009851200  0.63
2001 Wang DS, Hsu AL, Chen CS. A phosphatidylinositol 3,4,5-trisphosphate analogue with low serum protein-binding affinity. Bioorganic & Medicinal Chemistry. 9: 133-9. PMID 11197333  0.423
2000 Hsu AL, Ching TT, Wang DS, Song X, Rangnekar VM, Chen CS. The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. The Journal of Biological Chemistry. 275: 11397-403. PMID 10753955 DOI: 10.1074/Jbc.275.15.11397  0.678
2000 Hsu AL, Ching TT, Sen G, Wang DS, Bondada S, Authi KS, Chen CS. Novel function of phosphoinositide 3-kinase in T cell Ca2+ signaling. A phosphatidylinositol 3,4,5-trisphosphate-mediated Ca2+ entry mechanism. The Journal of Biological Chemistry. 275: 16242-50. PMID 10748064 DOI: 10.1074/Jbc.M002077200  0.623
1999 Ching TT, Wang DS, Hsu AL, Lu PJ, Chen CS. Identification of multiple phosphoinositide-specific phospholipases D as new regulatory enzymes for phosphatidylinositol 3,4, 5-trisphosphate. The Journal of Biological Chemistry. 274: 8611-7. PMID 10085097  0.605
1998 Lu PJ, Hsu AL, Wang DS, Chen CS. Phosphatidylinositol 3,4,5-trisphosphate triggers platelet aggregation by activating Ca2+ influx. Biochemistry. 37: 9776-83. PMID 9657691 DOI: 10.1021/bi980163o  0.432
1998 Lu PJ, Hsu AL, Wang DS, Yan HY, Yin HL, Chen CS. Phosphoinositide 3-kinase in rat liver nuclei. Biochemistry. 37: 5738-45. PMID 9548960 DOI: 10.1021/bi972551g  0.432
1998 Hsu AL, Lu PJ, Chen CS. Regulation of nuclear calcium uptake by inositol phosphates and external calcium. Biochemical and Biophysical Research Communications. 243: 653-6. PMID 9500990 DOI: 10.1006/bbrc.1998.8161  0.433
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