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Malene Hansen - Publications

Affiliations: 
Sanford-Burnham Medical Research Institute, USA 
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lim SHY, Hansen M, Kumsta C. Molecular Mechanisms of Autophagy Decline during Aging. Cells. 13. PMID 39195254 DOI: 10.3390/cells13161364  0.758
2024 Sun LH, Lange CM, Hansen M, Kumsta C. Neuronal waste management: new roles for autophagy genes in the extrusion of protein aggregates and in longevity. Autophagy. 1-3. PMID 38411179 DOI: 10.1080/15548627.2024.2322420  0.735
2024 Yang Y, Arnold ML, Lange CM, Sun LH, Broussalian M, Doroodian S, Ebata H, Choy EH, Poon K, Moreno TM, Singh A, Driscoll M, Kumsta C, Hansen M. Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons. Nature Aging. PMID 38177330 DOI: 10.1038/s43587-023-00548-1  0.741
2023 Chamoli M, Rane A, Foulger A, Chinta SJ, Shahmirzadi AA, Kumsta C, Nambiar DK, Hall D, Holcom A, Angeli S, Schmidt M, Pitteri S, Hansen M, Lithgow GJ, Andersen JK. A drug-like molecule engages nuclear hormone receptor DAF-12/FXR to regulate mitophagy and extend lifespan. Nature Aging. PMID 37957360 DOI: 10.1038/s43587-023-00524-9  0.742
2022 Lim CY, Lin HT, Kumsta C, Lu TC, Wang FY, Kang YH, Hansen M, Ching TT, Hsu AL. SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity. Autophagy. 1-17. PMID 35503435 DOI: 10.1080/15548627.2022.2068267  0.781
2022 Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, et al. Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 35000205 DOI: 10.1111/nyas.14745  0.571
2021 Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF. Autophagy in healthy aging and disease. Nature Aging. 1: 634-650. PMID 34901876 DOI: 10.1038/s43587-021-00098-4  0.321
2021 Nieto-Torres JL, Hansen M. Macroautophagy and aging: The impact of cellular recycling on health and longevity. Molecular Aspects of Medicine. 101020. PMID 34507801 DOI: 10.1016/j.mam.2021.101020  0.323
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Hansen M, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.741
2020 Aragonès G, Dasuri K, Olukorede O, Francisco SG, Renneburg C, Kumsta C, Hansen M, Kageyama S, Komatsu M, Rowan S, Volkin J, Workman M, Yang W, Daza P, Ruano D, et al. Autophagic receptor p62 protects against glycation-derived toxicity and enhances viability. Aging Cell. e13257. PMID 33146912 DOI: 10.1111/acel.13257  0.727
2020 Chang JT, Hansen M, Kumsta C. Correction to: Assessing Tissue-Specific Autophagy Flux in Adult Caenorhabditis elegans. Methods in Molecular Biology (Clifton, N.J.). 2144: C1. PMID 32749659 DOI: 10.1007/978-1-0716-0592-9_24  0.701
2020 Chang JT, Hansen M, Kumsta C. Asessing Tissue-Specific Autophagy Flux in Adult Caenorhabditis elegans. Methods in Molecular Biology (Clifton, N.J.). 2144: 187-200. PMID 32410036 DOI: 10.1007/978-1-0716-0592-9_17  0.761
2020 Aparicio R, Hansen M, Walker DW, Kumsta C. The selective autophagy receptor SQSTM1/p62 improves lifespan and proteostasis in an evolutionarily conserved manner. Autophagy. 1-3. PMID 32041473 DOI: 10.1080/15548627.2020.1725404  0.758
2020 Hansen M. Regulation of Autophagy in Aging and Disease Innovation in Aging. 4: 744-744. DOI: 10.1093/geroni/igaa057.2673  0.364
2020 Hansen M. Regulation of Autophagy in Aging and Disease Innovation in Aging. 4: 743-744. DOI: 10.1093/geroni/igaa057.2672  0.364
2019 Kumsta C, Chang JT, Lee R, Tan EP, Yang Y, Loureiro R, Choy EH, Lim SHY, Saez I, Springhorn A, Hoppe T, Vilchez D, Hansen M. The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy. Nature Communications. 10: 5648. PMID 31827090 DOI: 10.1038/s41467-019-13540-4  0.759
2019 Kumsta C, Hansen M. Getting under the skin: Cuticle damage elicits systemic autophagy response in . The Journal of Cell Biology. 218: 3885-3887. PMID 31723005 DOI: 10.1083/jcb.201911020  0.689
2019 Zhou B, Kreuzer J, Kumsta C, Wu L, Kamer KJ, Cedillo L, Zhang Y, Li S, Kacergis MC, Webster CM, Fejes-Toth G, Naray-Fejes-Toth A, Das S, Hansen M, Haas W, et al. Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension. Cell. PMID 30929899 DOI: 10.1016/J.Cell.2019.02.013  0.735
2018 Hansen M, Rubinsztein DC, Walker DW. Autophagy as a promoter of longevity: insights from model organisms. Nature Reviews. Molecular Cell Biology. PMID 30006559 DOI: 10.1038/s41580-018-0033-y  0.385
2018 Chang JT, Hansen M. Age-associated and tissue-specific decline in autophagic activity in the nematode C. elegans. Autophagy. 1-2. PMID 29806784 DOI: 10.1080/15548627.2018.1445914  0.314
2018 Lubas M, Harder LM, Kumsta C, Tiessen I, Hansen M, Andersen JS, Lund AH, Frankel LB. eIF5A is required for autophagy by mediating ATG3 translation. Embo Reports. PMID 29712776 DOI: 10.15252/embr.201846072  0.745
2017 Chang JT, Kumsta C, Hellman AB, Adams LM, Hansen M. Spatiotemporal regulation of autophagy during Caenorhabditis elegans aging. Elife. 6. PMID 28675140 DOI: 10.7554/eLife.18459  0.758
2017 Kumsta C, Hansen M. Hormetic heat shock and HSF-1 overexpression improve C. elegans survival and proteostasis by inducing autophagy. Autophagy. 13: 1076-1077. PMID 28333578 DOI: 10.1080/15548627.2017.1299313  0.733
2017 Kumsta C, Chang JT, Schmalz J, Hansen M. Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans. Nature Communications. 8: 14337. PMID 28198373 DOI: 10.1038/ncomms14337  0.73
2016 Gelino S, Chang JT, Kumsta C, She X, Davis A, Nguyen C, Panowski S, Hansen M. Correction: Intestinal Autophagy Improves Healthspan and Longevity in C. elegans During Dietary Restriction. Plos Genetics. 12: e1006271. PMID 27529578 DOI: 10.1371/Journal.Pgen.1006271  0.703
2016 Gelino S, Chang JT, Kumsta C, She X, Davis A, Nguyen C, Panowski S, Hansen M. Intestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary Restriction. Plos Genetics. 12: e1006135. PMID 27414651 DOI: 10.1371/Journal.Pgen.1006135  0.753
2016 McQuary PR, Liao CY, Chang JT, Kumsta C, She X, Davis A, Chu CC, Gelino S, Gomez-Amaro RL, Petrascheck M, Brill LM, Ladiges WC, Kennedy BK, Hansen M. C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension. Cell Reports. PMID 26923601 DOI: 10.1016/J.Celrep.2016.02.012  0.721
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Hansen M, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.651
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Hansen M, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.732
2015 Seah NE, de Magalhaes Filho CD, Petrashen AP, Henderson HR, Laguer J, Gonzalez J, Dillin A, Hansen M, Lapierre LR. Autophagy-mediated longevity is modulated by lipoprotein biogenesis. Autophagy. 0. PMID 26671266 DOI: 10.1080/15548627.2015.1127464  0.79
2015 Lapierre LR, Kumsta C, Sandri M, Ballabio A, Hansen M. Transcriptional and epigenetic regulation of autophagy in aging. Autophagy. 11: 867-80. PMID 25836756 DOI: 10.1080/15548627.2015.1034410  0.798
2015 Zhang H, Chang JT, Guo B, Hansen M, Jia K, Kovács AL, Kumsta C, Lapierre LR, Legouis R, Lin L, Lu Q, Meléndez A, O'Rourke EJ, Sato K, Sato M, et al. Guidelines for monitoring autophagy in Caenorhabditis elegans. Autophagy. 11: 9-27. PMID 25569839 DOI: 10.1080/15548627.2014.1003478  0.805
2015 Wilkinson DS, Jariwala JS, Anderson E, Mitra K, Meisenhelder J, Chang JT, Ideker T, Hunter T, Nizet V, Dillin A, Hansen M. Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy. Molecular Cell. 57: 55-68. PMID 25544559 DOI: 10.1016/J.Molcel.2014.11.019  0.589
2014 Nishimura M, Kumsta C, Kaushik G, Diop SB, Ding Y, Bisharat-Kernizan J, Catan H, Cammarato A, Ross RS, Engler AJ, Bodmer R, Hansen M, Ocorr K. A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. Aging Cell. 13: 431-40. PMID 24400780 DOI: 10.1111/Acel.12193  0.704
2014 Kumsta C, Ching TT, Nishimura M, Davis AE, Gelino S, Catan HH, Yu X, Chu CC, Ong B, Panowski SH, Baird N, Bodmer R, Hsu AL, Hansen M. Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. Aging Cell. 13: 419-30. PMID 24314125 DOI: 10.1111/Acel.12189  0.787
2013 Lapierre LR, De Magalhaes Filho CD, McQuary PR, Chu CC, Visvikis O, Chang JT, Gelino S, Ong B, Davis AE, Irazoqui JE, Dillin A, Hansen M. The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans. Nature Communications. 4: 2267. PMID 23925298 DOI: 10.1038/Ncomms3267  0.797
2013 Lapierre LR, Silvestrini MJ, Nuñez L, Ames K, Wong S, Le TT, Hansen M, Meléndez A. Autophagy genes are required for normal lipid levels in C. elegans. Autophagy. 9: 278-86. PMID 23321914 DOI: 10.4161/Auto.22930  0.743
2013 Schiavi A, Torgovnick A, Kell A, Megalou E, Castelein N, Guccini I, Marzocchella L, Gelino S, Hansen M, Malisan F, Condò I, Bei R, Rea SL, Braeckman BP, Tavernarakis N, et al. Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans. Experimental Gerontology. 48: 191-201. PMID 23247094 DOI: 10.1016/J.Exger.2012.12.002  0.341
2012 Gelino S, Hansen M. Autophagy - An Emerging Anti-Aging Mechanism. Journal of Clinical & Experimental Pathology. PMID 23750326 DOI: 10.4172/2161-0681.s4-006  0.381
2012 Lapierre LR, Hansen M. Lessons from C. elegans: signaling pathways for longevity. Trends in Endocrinology and Metabolism: Tem. 23: 637-44. PMID 22939742 DOI: 10.1016/J.Tem.2012.07.007  0.726
2012 Kumsta C, Hansen M. C. elegans rrf-1 mutations maintain RNAi efficiency in the soma in addition to the germline. Plos One. 7: e35428. PMID 22574120 DOI: 10.1371/journal.pone.0035428  0.731
2012 Lapierre LR, Meléndez A, Hansen M. Autophagy links lipid metabolism to longevity in C. elegans. Autophagy. 8: 144-6. PMID 22186228 DOI: 10.4161/Auto.8.1.18722  0.762
2011 Lapierre LR, Gelino S, Meléndez A, Hansen M. Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Current Biology : Cb. 21: 1507-14. PMID 21906946 DOI: 10.1016/J.Cub.2011.07.042  0.778
2011 Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, ... Hansen M, et al. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science (New York, N.Y.). 331: 456-61. PMID 21205641 DOI: 10.1126/Science.1196371  0.568
2010 Henis-Korenblit S, Zhang P, Hansen M, McCormick M, Lee SJ, Cary M, Kenyon C. Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity. Proceedings of the National Academy of Sciences of the United States of America. 107: 9730-5. PMID 20460307 DOI: 10.1073/Pnas.1002575107  0.655
2010 Hansen M, Kapahi P. TOR signaling and aging Enzymes. 28: 279-299. DOI: 10.1016/S1874-6047(10)28014-9  0.321
2008 Meléndez A, Hall DH, Hansen M. Monitoring the role of autophagy in C. elegans aging Methods in Enzymology. 451: 493-520. PMID 19185737  0.404
2008 Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C. A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. Plos Genetics. 4: e24. PMID 18282106 DOI: 10.1371/Journal.Pgen.0040024  0.572
2007 Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, Kenyon C. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell. 6: 95-110. PMID 17266679 DOI: 10.1111/J.1474-9726.2006.00267.X  0.782
2006 Pinkston JM, Garigan D, Hansen M, Kenyon C. Mutations that increase the life span of C. elegans inhibit tumor growth. Science (New York, N.Y.). 313: 971-5. PMID 16917064 DOI: 10.1126/Science.1121908  0.655
2005 Hansen M, Hsu AL, Dillin A, Kenyon C. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. Plos Genetics. 1: 119-28. PMID 16103914 DOI: 10.1371/Journal.Pgen.0010017  0.747
2005 Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C. A Role for Autophagy Genes in the Extension of Lifespan by Dietary Restriction in C. elegans Plos Genetics. DOI: 10.1371/Journal.Pgen.0040024.Eor  0.505
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