| Year |
Citation |
Score |
| 2024 |
Thompson J, Boisvert FM, Salsman J, Lévesque D, Dellaire G, Ridgway ND. The proximity interactome of PML isoforms I and II under fatty acid stress. Febs Letters. PMID 39703998 DOI: 10.1002/1873-3468.15081 |
0.311 |
|
| 2024 |
McPhee M, Lee J, Salsman J, Pinelli M, Di Cara F, Rosen K, Dellaire G, Ridgway ND. NUCLEAR LIPID DROPLETS IN CACO2 CELLS ORIGINATE FROM NASCENT PRECURSORS AND IN SITU AT THE NUCLEAR ENVELOPE. Journal of Lipid Research. 100540. PMID 38570093 DOI: 10.1016/j.jlr.2024.100540 |
0.379 |
|
| 2024 |
Foster J, McPhee M, Yue L, Dellaire G, Pelech S, Ridgway ND. Lipid- and Phospho-Regulation of CTP:Phosphocholine Cytidylyltransferase α Association with Nuclear Lipid Droplets. Molecular Biology of the Cell. mbcE23090354. PMID 38170618 DOI: 10.1091/mbc.E23-09-0354 |
0.302 |
|
| 2023 |
Dorighello G, McPhee M, Halliday K, Dellaire G, Ridgway ND. Differential contributions of phosphotransferases CEPT1 and CHPT1 to phosphatidylcholine homeostasis and lipid droplet biogenesis. The Journal of Biological Chemistry. 299: 104578. PMID 36871755 DOI: 10.1016/j.jbc.2023.104578 |
0.395 |
|
| 2022 |
McPhee MJ, Salsman J, Foster J, Thompson J, Mathavarajah S, Dellaire G, Ridgway ND. Running 'LAPS' Around nLD: Nuclear Lipid Droplet Form and Function. Frontiers in Cell and Developmental Biology. 10: 837406. PMID 35178392 DOI: 10.3389/fcell.2022.837406 |
0.348 |
|
| 2020 |
Lee J, Salsman J, Foster J, Dellaire G, Ridgway ND. Lipid-associated PML structures assemble nuclear lipid droplets containing CCTα and Lipin1. Life Science Alliance. 3. PMID 32461215 DOI: 10.26508/lsa.202000751 |
0.362 |
|
| 2020 |
Zhao K, Foster J, Ridgway ND. Oxysterol binding protein-related protein 1 (ORP1) variants have opposing cholesterol transport activities from the endolysosomes. Molecular Biology of the Cell. mbcE19120697. PMID 32023146 DOI: 10.1091/mbc.E19-12-0697 |
0.427 |
|
| 2019 |
Pietrangelo A, Ridgway ND. Phosphorylation of a serine/proline-rich motif in oxysterol binding protein-related protein 4L (ORP4L) regulates cholesterol and vimentin binding. Plos One. 14: e0214768. PMID 30925160 DOI: 10.1371/journal.pone.0214768 |
0.359 |
|
| 2018 |
Lee J, Ridgway ND. Phosphatidylcholine synthesis regulates triglyceride storage and chylomicron secretion by Caco2 cells. Journal of Lipid Research. PMID 30115754 DOI: 10.1194/jlr.M087635 |
0.351 |
|
| 2018 |
Goto A, Charman M, Ridgway ND. Protein kinase D1 and oxysterol binding protein form a regulatory complex independent of phosphorylation. Traffic (Copenhagen, Denmark). PMID 30101477 DOI: 10.1111/tra.12609 |
0.337 |
|
| 2018 |
Pietrangelo A, Ridgway ND. Golgi- localization of oxysterol binding protein-related protein 4L (ORP4L) is regulated by ligand binding. Journal of Cell Science. PMID 29930082 DOI: 10.1242/jcs.215335 |
0.368 |
|
| 2018 |
Ridgway ND. How CCTα puts a leash on phospholipid synthesis. The Journal of Biological Chemistry. 293: 7085-7086. PMID 29728535 DOI: 10.1074/jbc.H118.002882 |
0.331 |
|
| 2018 |
Ridgway ND, Zhao K. Cholesterol transfer at endosomal-organelle membrane contact sites. Current Opinion in Lipidology. PMID 29629999 DOI: 10.1097/MOL.0000000000000506 |
0.316 |
|
| 2018 |
Pietrangelo A, Ridgway ND. Bridging the molecular and biological functions of the oxysterol-binding protein family. Cellular and Molecular Life Sciences : Cmls. PMID 29536114 DOI: 10.1007/s00018-018-2795-y |
0.366 |
|
| 2018 |
Huang J, Mousley CJ, Dacquay L, Maitra N, Drin G, He C, Ridgway ND, Tripathi A, Kennedy M, Kennedy BK, Liu W, Baetz K, Polymenis M, Bankaitis VA. A Lipid Transfer Protein Signaling Axis Exerts Dual Control of Cell-Cycle and Membrane Trafficking Systems. Developmental Cell. PMID 29396115 DOI: 10.1016/J.Devcel.2017.12.026 |
0.365 |
|
| 2017 |
Zhao K, Ridgway ND. Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System. Cell Reports. 19: 1807-1818. PMID 28564600 DOI: 10.1016/j.celrep.2017.05.028 |
0.429 |
|
| 2017 |
Charman M, Goto A, Ridgway ND. Oxysterol binding protein recruitment and activity at the ER-Golgi interface are independent of Sac1. Traffic (Copenhagen, Denmark). PMID 28471037 DOI: 10.1111/tra.12491 |
0.366 |
|
| 2015 |
Goto A, Charman M, Ridgway ND. Oxysterol binding protein activation at endoplasmic reticulum-golgi contact sites reorganizes phosphatidylinositol 4-phosphate pools. The Journal of Biological Chemistry. PMID 26601944 DOI: 10.1074/jbc.M115.682997 |
0.311 |
|
| 2015 |
Aitchison AJ, Arsenault DJ, Ridgway ND. Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesis. Molecular Biology of the Cell. 26: 2927-38. PMID 26108622 DOI: 10.1091/mbc.E15-03-0159 |
0.335 |
|
| 2014 |
Liu X, Ridgway ND. Characterization of the sterol and phosphatidylinositol 4-phosphate binding properties of Golgi-associated OSBP-related protein 9 (ORP9). Plos One. 9: e108368. PMID 25255026 DOI: 10.1371/journal.pone.0108368 |
0.339 |
|
| 2014 |
Charman M, Colbourne TR, Pietrangelo A, Kreplak L, Ridgway ND. Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival. The Journal of Biological Chemistry. 289: 15705-17. PMID 24742681 DOI: 10.1074/jbc.M114.571216 |
0.455 |
|
| 2013 |
Morton CC, Aitchison AJ, Gehrig K, Ridgway ND. A mechanism for suppression of the CDP-choline pathway during apoptosis. Journal of Lipid Research. 54: 3373-84. PMID 24136823 DOI: 10.1194/jlr.M041434 |
0.314 |
|
| 2013 |
Lagace TA, Ridgway ND. The role of phospholipids in the biological activity and structure of the endoplasmic reticulum. Biochimica Et Biophysica Acta. 1833: 2499-510. PMID 23711956 DOI: 10.1016/J.Bbamcr.2013.05.018 |
0.706 |
|
| 2013 |
Ridgway ND. The role of phosphatidylcholine and choline metabolites to cell proliferation and survival. Critical Reviews in Biochemistry and Molecular Biology. 48: 20-38. PMID 23350810 DOI: 10.3109/10409238.2012.735643 |
0.338 |
|
| 2012 |
Goto A, Liu X, Robinson CA, Ridgway ND. Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis. Molecular Biology of the Cell. 23: 3624-35. PMID 22875984 DOI: 10.1091/mbc.E12-04-0283 |
0.381 |
|
| 2011 |
Gehrig K, Ridgway ND. CTP:phosphocholine cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure without affecting phosphatidylcholine synthesis. Biochimica Et Biophysica Acta. 1811: 377-85. PMID 21504799 DOI: 10.1016/j.bbalip.2011.04.001 |
0.379 |
|
| 2010 |
Banerji S, Ngo M, Lane CF, Robinson CA, Minogue S, Ridgway ND. Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIα. Molecular Biology of the Cell. 21: 4141-50. PMID 20881054 DOI: 10.1091/mbc.E10-05-0424 |
0.479 |
|
| 2010 |
Ngo MH, Colbourne TR, Ridgway ND. Functional implications of sterol transport by the oxysterol-binding protein gene family. The Biochemical Journal. 429: 13-24. PMID 20545625 DOI: 10.1042/BJ20100263 |
0.323 |
|
| 2010 |
Nhek S, Ngo M, Yang X, Ng MM, Field SJ, Asara JM, Ridgway ND, Toker A. Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation. Molecular Biology of the Cell. 21: 2327-37. PMID 20444975 DOI: 10.1091/Mbc.E10-02-0090 |
0.342 |
|
| 2010 |
Ridgway ND. Oxysterol-binding proteins. Sub-Cellular Biochemistry. 51: 159-82. PMID 20213544 DOI: 10.1007/978-90-481-8622-8_6 |
0.388 |
|
| 2009 |
Ngo M, Ridgway ND. Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function. Molecular Biology of the Cell. 20: 1388-99. PMID 19129476 DOI: 10.1091/mbc.E08-09-0905 |
0.432 |
|
| 2009 |
Gehrig K, Morton CC, Ridgway ND. Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain. Journal of Lipid Research. 50: 966-76. PMID 19098306 DOI: 10.1194/jlr.M800632-JLR200 |
0.445 |
|
| 2009 |
Gehrig K, Lagace TA, Ridgway ND. Oxysterol activation of phosphatidylcholine synthesis involves CTP:phosphocholine cytidylyltransferase alpha translocation to the nuclear envelope. The Biochemical Journal. 418: 209-17. PMID 18980580 DOI: 10.1042/Bj20081923 |
0.753 |
|
| 2008 |
Bowden K, Ridgway ND. OSBP negatively regulates ABCA1 protein stability. The Journal of Biological Chemistry. 283: 18210-7. PMID 18450749 DOI: 10.1074/jbc.M800918200 |
0.501 |
|
| 2008 |
Gehrig K, Cornell RB, Ridgway ND. Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha. Molecular Biology of the Cell. 19: 237-47. PMID 17959832 DOI: 10.1091/mbc.E07-02-0179 |
0.337 |
|
| 2008 |
Banerji S, Ridgway ND. Activation of sphingomyelin synthesis by oxysterol binding protein involves phosphatidylinositol 4-kinase activation at the Golgi Chemistry and Physics of Lipids. 154: S9. DOI: 10.1016/j.chemphyslip.2008.05.025 |
0.335 |
|
| 2007 |
Wyles JP, Perry RJ, Ridgway ND. Characterization of the sterol-binding domain of oxysterol-binding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization. Experimental Cell Research. 313: 1426-37. PMID 17350617 DOI: 10.1016/J.Yexcr.2007.01.018 |
0.737 |
|
| 2006 |
Perry RJ, Ridgway ND. Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein. Molecular Biology of the Cell. 17: 2604-16. PMID 16571669 DOI: 10.1091/mbc.E06-01-0060 |
0.471 |
|
| 2005 |
Lagace TA, Ridgway ND. Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha). The Biochemical Journal. 392: 449-56. PMID 16097951 DOI: 10.1042/Bj20051021 |
0.693 |
|
| 2005 |
Perry RJ, Ridgway ND. Molecular mechanisms and regulation of ceramide transport. Biochimica Et Biophysica Acta. 1734: 220-34. PMID 15907394 DOI: 10.1016/j.bbalip.2005.04.001 |
0.407 |
|
| 2005 |
Lagace TA, Ridgway ND. The rate-limiting enzyme in phosphatidylcholine synthesis regulates proliferation of the nucleoplasmic reticulum. Molecular Biology of the Cell. 16: 1120-30. PMID 15635091 DOI: 10.1091/Mbc.E04-10-0874 |
0.735 |
|
| 2004 |
Wyles JP, Ridgway ND. VAMP-associated protein-A regulates partitioning of oxysterol-binding protein-related protein-9 between the endoplasmic reticulum and Golgi apparatus. Experimental Cell Research. 297: 533-47. PMID 15212954 DOI: 10.1016/J.Yexcr.2004.03.052 |
0.741 |
|
| 2004 |
Perry RJ, Ridgway ND. The role of de novo ceramide synthesis in the mechanism of action of the tricyclic xanthate D609. Journal of Lipid Research. 45: 164-73. PMID 13130125 DOI: 10.1194/jlr.M300300-JLR200 |
0.303 |
|
| 2003 |
Ridgway ND, Lagace TA. Regulation of the CDP-choline pathway by sterol regulatory element binding proteins involves transcriptional and post-transcriptional mechanisms. The Biochemical Journal. 372: 811-9. PMID 12659631 DOI: 10.1042/Bj20030252 |
0.742 |
|
| 2003 |
Yu A, McMaster CR, Byers DM, Ridgway ND, Cook HW. Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1. The Journal of Biological Chemistry. 278: 9706-14. PMID 12509439 DOI: 10.1074/Jbc.M204614200 |
0.326 |
|
| 2002 |
Lagace TA, Miller JR, Ridgway ND. Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis. Molecular and Cellular Biology. 22: 4851-62. PMID 12052891 DOI: 10.1128/Mcb.22.13.4851-4862.2002 |
0.683 |
|
| 2002 |
Wyles JP, McMaster CR, Ridgway ND. Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum. The Journal of Biological Chemistry. 277: 29908-18. PMID 12023275 DOI: 10.1074/Jbc.M201191200 |
0.748 |
|
| 2002 |
Wang C, JeBailey L, Ridgway ND. Oxysterol-binding-protein (OSBP)-related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments. The Biochemical Journal. 361: 461-72. PMID 11802775 DOI: 10.1042/0264-6021:3610461 |
0.448 |
|
| 2001 |
Wright MM, Henneberry AL, Lagace TA, Ridgway ND, McMaster CR. Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis. The Journal of Biological Chemistry. 276: 25254-61. PMID 11306571 DOI: 10.1074/Jbc.M011552200 |
0.696 |
|
| 2001 |
Xu Y, Liu Y, Ridgway ND, McMaster CR. Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport. The Journal of Biological Chemistry. 276: 18407-14. PMID 11279184 DOI: 10.1074/jbc.M101204200 |
0.394 |
|
| 2001 |
Henneberry AL, Lagace TA, Ridgway ND, McMaster CR. Phosphatidylcholine synthesis influences the diacylglycerol homeostasis required for SEC14p-dependent Golgi function and cell growth. Molecular Biology of the Cell. 12: 511-20. PMID 11251067 DOI: 10.1091/Mbc.12.3.511 |
0.721 |
|
| 2000 |
Yu A, Byers DM, Ridgway ND, McMaster CR, Cook HW. Preferential externalization of newly synthesized phosphatidylserine in apoptotic U937 cells is dependent on caspase-mediated pathways. Biochimica Et Biophysica Acta. 1487: 296-308. PMID 11018481 DOI: 10.1016/S1388-1981(00)00100-1 |
0.31 |
|
| 2000 |
Lagace TA, Storey MK, Ridgway ND. Regulation of phosphatidylcholine metabolism in Chinese hamster ovary cells by the sterol regulatory element-binding protein (SREBP)/SREBP cleavage-activating protein pathway. The Journal of Biological Chemistry. 275: 14367-74. PMID 10799518 DOI: 10.1074/Jbc.275.19.14367 |
0.753 |
|
| 2000 |
Ridgway ND. Interactions between metabolism and intracellular distribution of cholesterol and sphingomyelin. Biochimica Et Biophysica Acta. 1484: 129-41. PMID 10760463 DOI: 10.1016/S1388-1981(00)00006-8 |
0.356 |
|
| 1999 |
Ridgway ND, Byers DM, Cook HW, Storey MK. Integration of phospholipid and sterol metabolism in mammalian cells. Progress in Lipid Research. 38: 337-60. PMID 10793888 DOI: 10.1016/S0163-7827(99)00007-7 |
0.335 |
|
| 1999 |
Lagace TA, Byers DM, Cook HW, Ridgway ND. Chinese hamster ovary cells overexpressing the oxysterol binding protein (OSBP) display enhanced synthesis of sphingomyelin in response to 25-hydroxycholesterol. Journal of Lipid Research. 40: 109-16. PMID 9869656 |
0.74 |
|
| 1998 |
Ridgway ND, Lagace TA, Cook HW, Byers DM. Differential effects of sphingomyelin hydrolysis and cholesterol transport on oxysterol-binding protein phosphorylation and Golgi localization. The Journal of Biological Chemistry. 273: 31621-8. PMID 9813079 DOI: 10.1074/Jbc.273.47.31621 |
0.728 |
|
| 1998 |
Storey MK, Byers DM, Cook HW, Ridgway ND. Cholesterol regulates oxysterol binding protein (OSBP) phosphorylation and Golgi localization in Chinese hamster ovary cells: correlation with stimulation of sphingomyelin synthesis by 25-hydroxycholesterol. The Biochemical Journal. 336: 247-56. PMID 9806908 DOI: 10.1042/Bj3360247 |
0.394 |
|
| 1997 |
Lagace TA, Byers DM, Cook HW, Ridgway ND. Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain. The Biochemical Journal. 326: 205-13. PMID 9337870 DOI: 10.1042/Bj3260205 |
0.757 |
|
| 1995 |
Ridgway ND, Lagace TA. Brefeldin A renders Chinese hamster ovary cells insensitive to transcriptional suppression by 25-hydroxycholesterol. The Journal of Biological Chemistry. 270: 8023-31. PMID 7713903 DOI: 10.1074/Jbc.270.14.8023 |
0.715 |
|
| 1994 |
Byers DM, Douglas JA, Cook HW, Palmer FB, Ridgway ND. Regulation of intracellular cholesterol metabolism is defective in lymphoblasts from Niemann-Pick type C and type D patients. Biochimica Et Biophysica Acta. 1226: 173-80. PMID 8204665 DOI: 10.1016/0925-4439(94)90026-4 |
0.313 |
|
| 1994 |
Rosé SD, Cook HW, Palmer FB, Ridgway ND, Byers DM. Differential expression of MARCKS and other calmodulin-binding protein kinase C substrates in cultured neuroblastoma and glioma cells. Journal of Neurochemistry. 63: 2314-23. PMID 7964753 DOI: 10.1046/J.1471-4159.1994.63062314.X |
0.324 |
|
| 1992 |
Ridgway ND, Dawson PA, Ho YK, Brown MS, Goldstein JL. Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding. The Journal of Cell Biology. 116: 307-19. PMID 1730758 DOI: 10.1083/jcb.116.2.307 |
0.45 |
|
| 1984 |
Ridgway N, Dolphin PJ. Lipoprotein lipase-mediated sequestration of long-chain polyunsaturated triacylglycerols in serum LDL from normal and hypothyroid rats. Biochimica Et Biophysica Acta. 796: 64-71. PMID 6487646 DOI: 10.1016/0005-2760(84)90239-X |
0.319 |
|
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