| Year |
Citation |
Score |
| 2024 |
Foster J, McPhee M, Yue L, Dellaire G, Pelech S, Ridgway ND. Lipid- and Phospho-Regulation of CTP:Phosphocholine Cytidylyltransferase α Association with Nuclear Lipid Droplets. Molecular Biology of the Cell. mbcE23090354. PMID 38170618 DOI: 10.1091/mbc.E23-09-0354 |
0.302 |
|
| 2023 |
Dorighello G, McPhee M, Halliday K, Dellaire G, Ridgway ND. Differential contributions of phosphotransferases CEPT1 and CHPT1 to phosphatidylcholine homeostasis and lipid droplet biogenesis. The Journal of Biological Chemistry. 299: 104578. PMID 36871755 DOI: 10.1016/j.jbc.2023.104578 |
0.395 |
|
| 2022 |
McPhee MJ, Salsman J, Foster J, Thompson J, Mathavarajah S, Dellaire G, Ridgway ND. Running 'LAPS' Around nLD: Nuclear Lipid Droplet Form and Function. Frontiers in Cell and Developmental Biology. 10: 837406. PMID 35178392 DOI: 10.3389/fcell.2022.837406 |
0.348 |
|
| 2020 |
Lee J, Salsman J, Foster J, Dellaire G, Ridgway ND. Lipid-associated PML structures assemble nuclear lipid droplets containing CCTα and Lipin1. Life Science Alliance. 3. PMID 32461215 DOI: 10.26508/lsa.202000751 |
0.362 |
|
| 2020 |
Zhao K, Foster J, Ridgway ND. Oxysterol binding protein-related protein 1 (ORP1) variants have opposing cholesterol transport activities from the endolysosomes. Molecular Biology of the Cell. mbcE19120697. PMID 32023146 DOI: 10.1091/mbc.E19-12-0697 |
0.427 |
|
| 2019 |
Pietrangelo A, Ridgway ND. Phosphorylation of a serine/proline-rich motif in oxysterol binding protein-related protein 4L (ORP4L) regulates cholesterol and vimentin binding. Plos One. 14: e0214768. PMID 30925160 DOI: 10.1371/journal.pone.0214768 |
0.359 |
|
| 2018 |
Lee J, Ridgway ND. Phosphatidylcholine synthesis regulates triglyceride storage and chylomicron secretion by Caco2 cells. Journal of Lipid Research. PMID 30115754 DOI: 10.1194/jlr.M087635 |
0.35 |
|
| 2018 |
Goto A, Charman M, Ridgway ND. Protein kinase D1 and oxysterol binding protein form a regulatory complex independent of phosphorylation. Traffic (Copenhagen, Denmark). PMID 30101477 DOI: 10.1111/tra.12609 |
0.337 |
|
| 2018 |
Pietrangelo A, Ridgway ND. Golgi- localization of oxysterol binding protein-related protein 4L (ORP4L) is regulated by ligand binding. Journal of Cell Science. PMID 29930082 DOI: 10.1242/jcs.215335 |
0.368 |
|
| 2018 |
Ridgway ND. How CCTα puts a leash on phospholipid synthesis. The Journal of Biological Chemistry. 293: 7085-7086. PMID 29728535 DOI: 10.1074/jbc.H118.002882 |
0.331 |
|
| 2018 |
Ridgway ND, Zhao K. Cholesterol transfer at endosomal-organelle membrane contact sites. Current Opinion in Lipidology. PMID 29629999 DOI: 10.1097/MOL.0000000000000506 |
0.316 |
|
| 2018 |
Pietrangelo A, Ridgway ND. Bridging the molecular and biological functions of the oxysterol-binding protein family. Cellular and Molecular Life Sciences : Cmls. PMID 29536114 DOI: 10.1007/s00018-018-2795-y |
0.366 |
|
| 2018 |
Huang J, Mousley CJ, Dacquay L, Maitra N, Drin G, He C, Ridgway ND, Tripathi A, Kennedy M, Kennedy BK, Liu W, Baetz K, Polymenis M, Bankaitis VA. A Lipid Transfer Protein Signaling Axis Exerts Dual Control of Cell-Cycle and Membrane Trafficking Systems. Developmental Cell. PMID 29396115 DOI: 10.1016/J.Devcel.2017.12.026 |
0.365 |
|
| 2017 |
Zhao K, Ridgway ND. Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System. Cell Reports. 19: 1807-1818. PMID 28564600 DOI: 10.1016/j.celrep.2017.05.028 |
0.429 |
|
| 2017 |
Charman M, Goto A, Ridgway ND. Oxysterol binding protein recruitment and activity at the ER-Golgi interface are independent of Sac1. Traffic (Copenhagen, Denmark). PMID 28471037 DOI: 10.1111/tra.12491 |
0.366 |
|
| 2015 |
Goto A, Charman M, Ridgway ND. Oxysterol binding protein activation at endoplasmic reticulum-golgi contact sites reorganizes phosphatidylinositol 4-phosphate pools. The Journal of Biological Chemistry. PMID 26601944 DOI: 10.1074/jbc.M115.682997 |
0.311 |
|
| 2015 |
Aitchison AJ, Arsenault DJ, Ridgway ND. Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesis. Molecular Biology of the Cell. 26: 2927-38. PMID 26108622 DOI: 10.1091/mbc.E15-03-0159 |
0.335 |
|
| 2014 |
Liu X, Ridgway ND. Characterization of the sterol and phosphatidylinositol 4-phosphate binding properties of Golgi-associated OSBP-related protein 9 (ORP9). Plos One. 9: e108368. PMID 25255026 DOI: 10.1371/journal.pone.0108368 |
0.339 |
|
| 2014 |
Charman M, Colbourne TR, Pietrangelo A, Kreplak L, Ridgway ND. Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival. The Journal of Biological Chemistry. 289: 15705-17. PMID 24742681 DOI: 10.1074/jbc.M114.571216 |
0.455 |
|
| 2013 |
Morton CC, Aitchison AJ, Gehrig K, Ridgway ND. A mechanism for suppression of the CDP-choline pathway during apoptosis. Journal of Lipid Research. 54: 3373-84. PMID 24136823 DOI: 10.1194/jlr.M041434 |
0.314 |
|
| 2013 |
Lagace TA, Ridgway ND. The role of phospholipids in the biological activity and structure of the endoplasmic reticulum. Biochimica Et Biophysica Acta. 1833: 2499-510. PMID 23711956 DOI: 10.1016/J.Bbamcr.2013.05.018 |
0.706 |
|
| 2013 |
Ridgway ND. The role of phosphatidylcholine and choline metabolites to cell proliferation and survival. Critical Reviews in Biochemistry and Molecular Biology. 48: 20-38. PMID 23350810 DOI: 10.3109/10409238.2012.735643 |
0.338 |
|
| 2012 |
Goto A, Liu X, Robinson CA, Ridgway ND. Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis. Molecular Biology of the Cell. 23: 3624-35. PMID 22875984 DOI: 10.1091/mbc.E12-04-0283 |
0.381 |
|
| 2011 |
Gehrig K, Ridgway ND. CTP:phosphocholine cytidylyltransferase α (CCTα) and lamins alter nuclear membrane structure without affecting phosphatidylcholine synthesis. Biochimica Et Biophysica Acta. 1811: 377-85. PMID 21504799 DOI: 10.1016/j.bbalip.2011.04.001 |
0.379 |
|
| 2010 |
Banerji S, Ngo M, Lane CF, Robinson CA, Minogue S, Ridgway ND. Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIα. Molecular Biology of the Cell. 21: 4141-50. PMID 20881054 DOI: 10.1091/mbc.E10-05-0424 |
0.48 |
|
| 2010 |
Ngo MH, Colbourne TR, Ridgway ND. Functional implications of sterol transport by the oxysterol-binding protein gene family. The Biochemical Journal. 429: 13-24. PMID 20545625 DOI: 10.1042/BJ20100263 |
0.323 |
|
| 2010 |
Nhek S, Ngo M, Yang X, Ng MM, Field SJ, Asara JM, Ridgway ND, Toker A. Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation. Molecular Biology of the Cell. 21: 2327-37. PMID 20444975 DOI: 10.1091/Mbc.E10-02-0090 |
0.342 |
|
| 2010 |
Ridgway ND. Oxysterol-binding proteins. Sub-Cellular Biochemistry. 51: 159-82. PMID 20213544 DOI: 10.1007/978-90-481-8622-8_6 |
0.388 |
|
| 2009 |
Ngo M, Ridgway ND. Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function. Molecular Biology of the Cell. 20: 1388-99. PMID 19129476 DOI: 10.1091/mbc.E08-09-0905 |
0.432 |
|
| 2009 |
Gehrig K, Morton CC, Ridgway ND. Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain. Journal of Lipid Research. 50: 966-76. PMID 19098306 DOI: 10.1194/jlr.M800632-JLR200 |
0.445 |
|
| 2009 |
Gehrig K, Lagace TA, Ridgway ND. Oxysterol activation of phosphatidylcholine synthesis involves CTP:phosphocholine cytidylyltransferase alpha translocation to the nuclear envelope. The Biochemical Journal. 418: 209-17. PMID 18980580 DOI: 10.1042/Bj20081923 |
0.753 |
|
| 2008 |
Bowden K, Ridgway ND. OSBP negatively regulates ABCA1 protein stability. The Journal of Biological Chemistry. 283: 18210-7. PMID 18450749 DOI: 10.1074/jbc.M800918200 |
0.501 |
|
| 2008 |
Gehrig K, Cornell RB, Ridgway ND. Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha. Molecular Biology of the Cell. 19: 237-47. PMID 17959832 DOI: 10.1091/mbc.E07-02-0179 |
0.337 |
|
| 2008 |
Banerji S, Ridgway ND. Activation of sphingomyelin synthesis by oxysterol binding protein involves phosphatidylinositol 4-kinase activation at the Golgi Chemistry and Physics of Lipids. 154: S9. DOI: 10.1016/j.chemphyslip.2008.05.025 |
0.335 |
|
| 2007 |
Wyles JP, Perry RJ, Ridgway ND. Characterization of the sterol-binding domain of oxysterol-binding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization. Experimental Cell Research. 313: 1426-37. PMID 17350617 DOI: 10.1016/J.Yexcr.2007.01.018 |
0.737 |
|
| 2006 |
Perry RJ, Ridgway ND. Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein. Molecular Biology of the Cell. 17: 2604-16. PMID 16571669 DOI: 10.1091/mbc.E06-01-0060 |
0.471 |
|
| 2005 |
Lagace TA, Ridgway ND. Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha). The Biochemical Journal. 392: 449-56. PMID 16097951 DOI: 10.1042/Bj20051021 |
0.693 |
|
| 2005 |
Perry RJ, Ridgway ND. Molecular mechanisms and regulation of ceramide transport. Biochimica Et Biophysica Acta. 1734: 220-34. PMID 15907394 DOI: 10.1016/j.bbalip.2005.04.001 |
0.407 |
|
| 2005 |
Lagace TA, Ridgway ND. The rate-limiting enzyme in phosphatidylcholine synthesis regulates proliferation of the nucleoplasmic reticulum. Molecular Biology of the Cell. 16: 1120-30. PMID 15635091 DOI: 10.1091/Mbc.E04-10-0874 |
0.735 |
|
| 2004 |
Wyles JP, Ridgway ND. VAMP-associated protein-A regulates partitioning of oxysterol-binding protein-related protein-9 between the endoplasmic reticulum and Golgi apparatus. Experimental Cell Research. 297: 533-47. PMID 15212954 DOI: 10.1016/J.Yexcr.2004.03.052 |
0.741 |
|
| 2004 |
Perry RJ, Ridgway ND. The role of de novo ceramide synthesis in the mechanism of action of the tricyclic xanthate D609. Journal of Lipid Research. 45: 164-73. PMID 13130125 DOI: 10.1194/jlr.M300300-JLR200 |
0.303 |
|
| 2003 |
Ridgway ND, Lagace TA. Regulation of the CDP-choline pathway by sterol regulatory element binding proteins involves transcriptional and post-transcriptional mechanisms. The Biochemical Journal. 372: 811-9. PMID 12659631 DOI: 10.1042/Bj20030252 |
0.742 |
|
| 2003 |
Yu A, McMaster CR, Byers DM, Ridgway ND, Cook HW. Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1. The Journal of Biological Chemistry. 278: 9706-14. PMID 12509439 DOI: 10.1074/Jbc.M204614200 |
0.326 |
|
| 2002 |
Lagace TA, Miller JR, Ridgway ND. Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis. Molecular and Cellular Biology. 22: 4851-62. PMID 12052891 DOI: 10.1128/Mcb.22.13.4851-4862.2002 |
0.683 |
|
| 2002 |
Wyles JP, McMaster CR, Ridgway ND. Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum. The Journal of Biological Chemistry. 277: 29908-18. PMID 12023275 DOI: 10.1074/Jbc.M201191200 |
0.748 |
|
| 2002 |
Wang C, JeBailey L, Ridgway ND. Oxysterol-binding-protein (OSBP)-related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments. The Biochemical Journal. 361: 461-72. PMID 11802775 DOI: 10.1042/0264-6021:3610461 |
0.448 |
|
| 2001 |
Wright MM, Henneberry AL, Lagace TA, Ridgway ND, McMaster CR. Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis. The Journal of Biological Chemistry. 276: 25254-61. PMID 11306571 DOI: 10.1074/Jbc.M011552200 |
0.696 |
|
| 2001 |
Xu Y, Liu Y, Ridgway ND, McMaster CR. Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport. The Journal of Biological Chemistry. 276: 18407-14. PMID 11279184 DOI: 10.1074/jbc.M101204200 |
0.395 |
|
| 2001 |
Henneberry AL, Lagace TA, Ridgway ND, McMaster CR. Phosphatidylcholine synthesis influences the diacylglycerol homeostasis required for SEC14p-dependent Golgi function and cell growth. Molecular Biology of the Cell. 12: 511-20. PMID 11251067 DOI: 10.1091/Mbc.12.3.511 |
0.721 |
|
| 2000 |
Yu A, Byers DM, Ridgway ND, McMaster CR, Cook HW. Preferential externalization of newly synthesized phosphatidylserine in apoptotic U937 cells is dependent on caspase-mediated pathways. Biochimica Et Biophysica Acta. 1487: 296-308. PMID 11018481 DOI: 10.1016/S1388-1981(00)00100-1 |
0.31 |
|
| 2000 |
Lagace TA, Storey MK, Ridgway ND. Regulation of phosphatidylcholine metabolism in Chinese hamster ovary cells by the sterol regulatory element-binding protein (SREBP)/SREBP cleavage-activating protein pathway. The Journal of Biological Chemistry. 275: 14367-74. PMID 10799518 DOI: 10.1074/Jbc.275.19.14367 |
0.753 |
|
| 2000 |
Ridgway ND. Interactions between metabolism and intracellular distribution of cholesterol and sphingomyelin. Biochimica Et Biophysica Acta. 1484: 129-41. PMID 10760463 DOI: 10.1016/S1388-1981(00)00006-8 |
0.356 |
|
| 1999 |
Ridgway ND, Byers DM, Cook HW, Storey MK. Integration of phospholipid and sterol metabolism in mammalian cells. Progress in Lipid Research. 38: 337-60. PMID 10793888 DOI: 10.1016/S0163-7827(99)00007-7 |
0.335 |
|
| 1999 |
Lagace TA, Byers DM, Cook HW, Ridgway ND. Chinese hamster ovary cells overexpressing the oxysterol binding protein (OSBP) display enhanced synthesis of sphingomyelin in response to 25-hydroxycholesterol. Journal of Lipid Research. 40: 109-16. PMID 9869656 |
0.74 |
|
| 1998 |
Ridgway ND, Lagace TA, Cook HW, Byers DM. Differential effects of sphingomyelin hydrolysis and cholesterol transport on oxysterol-binding protein phosphorylation and Golgi localization. The Journal of Biological Chemistry. 273: 31621-8. PMID 9813079 DOI: 10.1074/Jbc.273.47.31621 |
0.728 |
|
| 1998 |
Storey MK, Byers DM, Cook HW, Ridgway ND. Cholesterol regulates oxysterol binding protein (OSBP) phosphorylation and Golgi localization in Chinese hamster ovary cells: correlation with stimulation of sphingomyelin synthesis by 25-hydroxycholesterol. The Biochemical Journal. 336: 247-56. PMID 9806908 DOI: 10.1042/Bj3360247 |
0.394 |
|
| 1997 |
Lagace TA, Byers DM, Cook HW, Ridgway ND. Altered regulation of cholesterol and cholesteryl ester synthesis in Chinese-hamster ovary cells overexpressing the oxysterol-binding protein is dependent on the pleckstrin homology domain. The Biochemical Journal. 326: 205-13. PMID 9337870 DOI: 10.1042/Bj3260205 |
0.757 |
|
| 1995 |
Ridgway ND, Lagace TA. Brefeldin A renders Chinese hamster ovary cells insensitive to transcriptional suppression by 25-hydroxycholesterol. The Journal of Biological Chemistry. 270: 8023-31. PMID 7713903 DOI: 10.1074/Jbc.270.14.8023 |
0.715 |
|
| 1994 |
Byers DM, Douglas JA, Cook HW, Palmer FB, Ridgway ND. Regulation of intracellular cholesterol metabolism is defective in lymphoblasts from Niemann-Pick type C and type D patients. Biochimica Et Biophysica Acta. 1226: 173-80. PMID 8204665 DOI: 10.1016/0925-4439(94)90026-4 |
0.313 |
|
| 1994 |
Rosé SD, Cook HW, Palmer FB, Ridgway ND, Byers DM. Differential expression of MARCKS and other calmodulin-binding protein kinase C substrates in cultured neuroblastoma and glioma cells. Journal of Neurochemistry. 63: 2314-23. PMID 7964753 DOI: 10.1046/J.1471-4159.1994.63062314.X |
0.324 |
|
| 1992 |
Ridgway ND, Dawson PA, Ho YK, Brown MS, Goldstein JL. Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding. The Journal of Cell Biology. 116: 307-19. PMID 1730758 DOI: 10.1083/jcb.116.2.307 |
0.45 |
|
| 1984 |
Ridgway N, Dolphin PJ. Lipoprotein lipase-mediated sequestration of long-chain polyunsaturated triacylglycerols in serum LDL from normal and hypothyroid rats. Biochimica Et Biophysica Acta. 796: 64-71. PMID 6487646 DOI: 10.1016/0005-2760(84)90239-X |
0.319 |
|
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