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Laura B. Ramsey, Ph.D. - Publications

Affiliations: 
2009 Molecular, Cellular, Developmental Biology and Genetics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Immunology
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ibarra M, Combs R, Taylor ZL, Ramsey LB, Mikkelsen T, Buddington RK, Heldrup J, Barreto JN, Guscott M, Lowe J, Hurmiz C, Marada S, Howard SC, Schaiquevich P. Insights from a pharmacometric analysis of HDMTX in adults with cancer: clinically relevant covariates for application in precision dosing. British Journal of Clinical Pharmacology. PMID 35998099 DOI: 10.1111/bcp.15506  0.649
2021 Mehta RS, Taylor ZL, Martin LJ, Rosen MJ, Ramsey LB. SLCO1B1 *15 allele is associated with methotrexate-induced nausea in pediatric patients with inflammatory bowel disease. Clinical and Translational Science. PMID 34423897 DOI: 10.1111/cts.13130  0.66
2021 Taylor ZL, Vang J, Lopez-Lopez E, Oosterom N, Mikkelsen T, Ramsey LB. Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies. Cancers. 13. PMID 34200242 DOI: 10.3390/cancers13112837  0.676
2021 Taylor ZL, Thompson LE, Bear H, Mizuno T, Vinks AA, Ramsey LB. Toward pharmacogenetic SLCO1B1-guided dosing of methotrexate in arthritis using a murine Slco1b2 knockout model. Clinical and Translational Science. PMID 34121338 DOI: 10.1111/cts.13086  0.658
2020 Taylor ZL, Mizuno T, Punt NC, Baskaran B, Navarro Sainz A, Shuman W, Felicelli N, Vinks AA, Heldrup J, Ramsey LB. MTXPK.org: A clinical decision support tool evaluating high-dose methotrexate pharmacokinetics to inform post-infusion care and use of glucarpidase. Clinical Pharmacology and Therapeutics. PMID 32558929 DOI: 10.1002/Cpt.1957  0.677
2020 Mizuno T, Dong M, Taylor ZL, Ramsey LB, Vinks AA. Clinical implementation of pharmacogenetics and model-informed precision dosing to improve patient care. British Journal of Clinical Pharmacology. PMID 32529759 DOI: 10.1111/Bcp.14426  0.662
2020 Ambrosino N, Teusink-Cross A, Lane A, Ramsey L, Mehta PA. CYP2C19 Metabolizer Status Does Not Influence the Safety or Efficacy of Pentamidine Biology of Blood and Marrow Transplantation. 26: S94. DOI: 10.1016/J.Bbmt.2019.12.596  0.303
2019 Ramsey LB, Brown JT, Vear SI, Bishop JR, Van Driest SL. Gene-Based Dose Optimization in Children. Annual Review of Pharmacology and Toxicology. PMID 31283429 DOI: 10.1146/Annurev-Pharmtox-010919-023459  0.308
2019 Poweleit EA, Aldrich SL, Martin LJ, Hahn D, Strawn JR, Ramsey LB. Pharmacogenetics of Sertraline Tolerability and Response in Pediatric Anxiety and Depressive Disorders. Journal of Child and Adolescent Psychopharmacology. PMID 31066578 DOI: 10.1089/Cap.2019.0017  0.37
2019 Strawn JR, Poweleit EA, Ramsey LB. CYP2C19-Guided Escitalopram and Sertraline Dosing in Pediatric Patients: A Pharmacokinetic Modeling Study. Journal of Child and Adolescent Psychopharmacology. PMID 30817183 DOI: 10.1089/Cap.2018.0160  0.327
2019 Ramsey LB, Mizuno T, Vinks AA, O'Brien MM. Delayed methotrexate clearance in patients with acute lymphoblastic leukemia concurrently receiving dasatinib. Pediatric Blood & Cancer. e27618. PMID 30677213 DOI: 10.1002/Pbc.27618  0.32
2018 Rahrmann EP, Wolf NK, Otto GM, Heltemes Harris L, Ramsey LB, Shu J, LaRue RS, Linden MA, Rathe SK, Starr TK, Farrar MA, Moriarity BS, Largaespada DA. Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma. Molecular Cancer Research : McR. PMID 30355676 DOI: 10.1158/1541-7786.Mcr-18-0582  0.644
2017 Ramsey LB, Balis FM, O'Brien MM, Schmiegelow K, Pauley JL, Bleyer A, Widemann BC, Askenazi D, Bergeron S, Shirali A, Schwartz S, Vinks AA, Heldrup J. Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance. The Oncologist. PMID 29079637 DOI: 10.1634/Theoncologist.2017-0243  0.307
2017 Maxwell WD, Ramsey LB, Johnson SG, Moore KG, Shtutman M, Schoonover JH, Kawaguchi-Suzuki M. Impact of Pharmacogenetics on Efficacy and Safety of Statin Therapy for Dyslipidemia. Pharmacotherapy. PMID 28672099 DOI: 10.1002/Phar.1981  0.307
2017 Ramsey LB, Pounds S, Cheng C, Cao X, Yang W, Smith C, Karol SE, Liu C, Panetta JC, Inaba H, Rubnitz JE, Metzger ML, Ribeiro RC, Sandlund JT, Jeha S, et al. Genetics of pleiotropic effects of dexamethasone. Pharmacogenetics and Genomics. PMID 28628558 DOI: 10.1097/Fpc.0000000000000293  0.31
2017 Katerndahl CD, Heltemes-Harris LM, Willette MJ, Henzler CM, Frietze S, Yang R, Schjerven H, Silverstein KA, Ramsey LB, Hubbard G, Wells AD, Kuiper RP, Scheijen B, van Leeuwen FN, Müschen M, et al. Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival. Nature Immunology. PMID 28369050 DOI: 10.1038/Ni.3716  0.694
2017 Karol SE, Larsen E, Cheng C, Cao X, Yang W, Ramsey LB, Fernandez CA, McCorkle JR, Paugh SW, Autry RJ, Lopez-Lopez E, Diouf B, Jeha S, Pui CH, Raetz EA, et al. Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia. Leukemia. PMID 28096535 DOI: 10.1038/Leu.2017.24  0.33
2017 Liu Y, Fernandez CA, Smith C, Yang W, Cheng C, Panetta JC, Kornegay N, Liu C, Ramsey LB, Karol SE, Janke LJ, Larsen EC, Winick N, Carroll WL, Loh ML, et al. Genome-wide study links PNPLA3 variant with elevated hepatic transaminase after acute lymphoblastic leukemia therapy. Clinical Pharmacology and Therapeutics. PMID 28090653 DOI: 10.1002/Cpt.629  0.306
2016 Liu C, Janke LJ, Kawedia JD, Ramsey LB, Cai X, Mattano LA, Boyd KL, Funk AJ, Relling MV. Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model. Plos One. 11: e0151433. PMID 26967741 DOI: 10.1371/Journal.Pone.0151433  0.332
2015 Karol SE, Mattano LA, Yang W, Maloney KW, Smith C, Liu C, Ramsey LB, Fernandez CA, Chang TY, Neale G, Cheng C, Mardis E, Fulton R, Scheet P, San Lucas FA, et al. Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia. Blood. PMID 26590194 DOI: 10.1182/Blood-2015-10-673848  0.328
2015 Ramsey LB, Janke LJ, Payton MA, Cai X, Paugh SW, Karol SE, Kamdem Kamdem L, Cheng C, Williams RT, Jeha S, Pui CH, Evans WE, Relling MV. Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia. Plos One. 10: e0135134. PMID 26252865 DOI: 10.1371/Journal.Pone.0135134  0.336
2015 Fernandez CA, Smith C, Yang W, Mullighan CG, Qu C, Larsen E, Bowman WP, Liu C, Ramsey LB, Chang T, Karol SE, Loh ML, Raetz EA, Winick NJ, Hunger SP, et al. Genome-wide analysis links NFATC2 with asparaginase hypersensitivity. Blood. PMID 25987655 DOI: 10.1182/Blood-2015-02-628800  0.332
2015 Paugh SW, Bonten EJ, Savic D, Ramsey LB, Thierfelder WE, Gurung P, Malireddi RK, Actis M, Mayasundari A, Min J, Coss DR, Laudermilk LT, Panetta JC, McCorkle JR, Fan Y, et al. NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells. Nature Genetics. 47: 607-14. PMID 25938942 DOI: 10.1038/Ng.3283  0.308
2015 Fernandez CA, Smith C, Karol SE, Ramsey LB, Liu C, Pui CH, Jeha S, Evans WE, Finkelman FD, Relling MV. Effect of premedications in a murine model of asparaginase hypersensitivity. The Journal of Pharmacology and Experimental Therapeutics. 352: 541-51. PMID 25573198 DOI: 10.1124/Jpet.114.220780  0.331
2015 Fernandez CA, Smith C, Yang W, Liu C, Ramsey LB, Karol SE, Pui C, Evans WE, Jeha S, Relling MV. Genome-Wide Association Study Identifies PNPLA3 I148M Variant Associated with Elevated Transaminase Levels after Induction Therapy in Pediatric ALL Patients Blood. 126: 3714-3714. DOI: 10.1182/Blood.V126.23.3714.3714  0.355
2014 Fernandez CA, Smith C, Yang W, Daté M, Bashford D, Larsen E, Bowman WP, Liu C, Ramsey LB, Chang T, Turner V, Loh ML, Raetz EA, Winick NJ, Hunger SP, et al. HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies. Blood. 124: 1266-76. PMID 24970932 DOI: 10.1182/Blood-2014-03-563742  0.309
2014 Fernandez CA, Smith C, Yang W, Mullighan CG, Qu C, Larsen EC, Bowman WP, Liu C, Ramsey LB, Chang T, Karol SE, Loh ML, Raetz EA, Winick NJ, Hunger S, et al. Genetic Variation in NFATC2 Is Associated with a Higher Risk of Asparaginase Allergy Blood. 124: 63-63. DOI: 10.1182/Blood.V124.21.63.63  0.366
2014 Ramsey LB, Janke L, Payton MA, Cai X, Jeha S, Pui C, Evans WE, Relling MV. Antileukemic Efficacy of Continuous Vs Discontinuous Dexamethasone in Murine Xenografts of Acute Lymphoblastic Leukemia Blood. 124: 3701-3701. DOI: 10.1182/Blood.V124.21.3701.3701  0.323
2014 Fernandez CA, Smith C, Karol SE, Ramsey LB, Liu C, Pui C, Jeha S, Evans WE, Finkelman FD, Relling MV. A Murine Model of Asparaginase Allergy Blood. 124: 2295-2295. DOI: 10.1182/Blood.V124.21.2295.2295  0.333
2013 Waibel M, Solomon VS, Knight DA, Ralli RA, Kim SK, Banks KM, Vidacs E, Virely C, Sia KC, Bracken LS, Collins-Underwood R, Drenberg C, Ramsey LB, Meyer SC, Takiguchi M, et al. Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors. Cell Reports. 5: 1047-59. PMID 24268771 DOI: 10.1016/J.Celrep.2013.10.038  0.343
2013 Fernandez CA, Relling MV, Smith C, Yang W, Larsen EC, Bowman WP, Liu C, Ramsey LB, Chang T, Turner V, Loh ML, Raetz EA, Winick NJ, Hunger SP, Carroll WL, et al. HLA-DRB1*07:01 Is Associated With Asparaginase Allergies In Children With Acute Lymphoblastic Leukemia Blood. 122: 60-60. DOI: 10.1182/Blood.V122.21.60.60  0.319
2012 Fernandez CA, Smith C, Yang W, Lorier R, Crews KR, Kornegay N, Hicks JK, Stewart CF, Kawedia JD, Ramsey LB, Liu C, Evans WE, Relling MV, Broeckel U. Concordance of DMET plus genotyping results with those of orthogonal genotyping methods. Clinical Pharmacology and Therapeutics. 92: 360-5. PMID 22871999 DOI: 10.1038/Clpt.2012.95  0.303
2012 Stocco G, Yang W, Crews KR, Thierfelder WE, Decorti G, Londero M, Franca R, Rabusin M, Valsecchi MG, Pei D, Cheng C, Paugh SW, Ramsey LB, Diouf B, McCorkle JR, et al. PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity. Human Molecular Genetics. 21: 4793-804. PMID 22846425 DOI: 10.1093/Hmg/Dds302  0.375
2012 Wilke RA, Ramsey LB, Johnson SG, Maxwell WD, McLeod HL, Voora D, Krauss RM, Roden DM, Feng Q, Cooper-Dehoff RM, Gong L, Klein TE, Wadelius M, Niemi M. The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy. Clinical Pharmacology and Therapeutics. 92: 112-7. PMID 22617227 DOI: 10.1038/Clpt.2012.57  0.322
2012 Johnson K, Chaumeil J, Micsinai M, Wang JM, Ramsey LB, Baracho GV, Rickert RC, Strino F, Kluger Y, Farrar MA, Skok JA. IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle. Journal of Immunology (Baltimore, Md. : 1950). 188: 6084-92. PMID 22581861 DOI: 10.4049/Jimmunol.1200368  0.626
2012 Ramsey LB, Bruun GH, Yang W, Treviño LR, Vattathil S, Scheet P, Cheng C, Rosner GL, Giacomini KM, Fan Y, Sparreboom A, Mikkelsen TS, Corydon TJ, Pui CH, Evans WE, et al. Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition. Genome Research. 22: 1-8. PMID 22147369 DOI: 10.1101/Gr.129668.111  0.32
2012 Yang JJ, E S, Shen S, Bhojwani D, Kang H, Ma Y, Chen J, Tang J, Seibel NL, Xu H, Cheng J, Ramsey LB, Crews K, Bowman WP, Borowitz MJ, et al. PDE4B Modulates Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia Blood. 120: 530-530. DOI: 10.1182/Blood.V120.21.530.530  0.361
2012 Ramsey LB, Janke L, Edick M, Cheng C, Williams RT, Sherr CJ, Evans WE, Relling MV. Host Thiopurine Methyltransferase Status Affects Mercaptopurine Antileukemic Effectiveness Blood. 120: 3560-3560. DOI: 10.1182/Blood.V120.21.3560.3560  0.347
2012 Ramsey LB, Panetta JC, Smith C, Yang W, Fan Y, Winick N, Martin PL, Cheng C, Devidas M, Pui C, Evans WE, Hunger SP, Loh ML, Relling MV. A Genome-Wide Analysis of Variants Influencing Methotrexate Clearance Replicates SLCO1B1. Blood. 120: 2466-2466. DOI: 10.1182/Blood.V120.21.2466.2466  0.35
2011 Heltemes-Harris LM, Willette MJ, Ramsey LB, Qiu YH, Neeley ES, Zhang N, Thomas DA, Koeuth T, Baechler EC, Kornblau SM, Farrar MA. Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia. The Journal of Experimental Medicine. 208: 1135-49. PMID 21606506 DOI: 10.1084/Jem.20101947  0.699
2011 Ramsey LB, Vegoe AL, Miller AT, Cooke MP, Farrar MA. Tonic BCR signaling represses receptor editing via Raf- and calcium-dependent signaling pathways. Immunology Letters. 135: 74-7. PMID 20933008 DOI: 10.1016/J.Imlet.2010.09.018  0.632
2011 Ramsey LB, Bruun GH, Yang W, Trevino LR, Vattathil S, Scheet P, Cheng C, Rosner G, Giacomini K, Fan Y, Sparreboom A, Mikkelsen T, Corydon TJ, Pui C, Evans WE, et al. SLCO1B1 Variation and Methotrexate Disposition in Children with Acute Lymphoblastic Leukemia: The Importance of Rare Variants in Pharmacogenetics Blood. 118: 571-571. DOI: 10.1182/Blood.V118.21.571.571  0.339
2010 Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, et al. Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci Nature Immunology. 11: 356-356. DOI: 10.1038/ni0410-356  0.552
2010 Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, et al. Addendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci Nature Immunology. 11: 355-356. DOI: 10.1038/Ni0410-355  0.585
2009 Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, et al. RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nature Immunology. 10: 655-64. PMID 19448632 DOI: 10.1038/Ni.1735  0.616
2008 Schram BR, Tze LE, Ramsey LB, Liu J, Najera L, Vegoe AL, Hardy RR, Hippen KL, Farrar MA, Behrens TW. B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements. Journal of Immunology (Baltimore, Md. : 1950). 180: 4728-41. PMID 18354197 DOI: 10.4049/Jimmunol.180.7.4728  0.649
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