Jason H. Moore - Publications

Affiliations: 
Program in Human Genetics, Bronxville, NY, United States 

352 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Freda PJ, Ye S, Zhang R, Moore JH, Urbanowicz RJ. Assessing the limitations of relief-based algorithms in detecting higher-order interactions. Biodata Mining. 17: 37. PMID 39354639 DOI: 10.1186/s13040-024-00390-0  0.688
2024 Quesnel-Vallières M, Schultz DC, Orlenko A, Lo Y, Moore J, Ritchie M, Roth D, Carroll M, Barash Y, Lynch KW, Cherry S. Trametinib Sensitivity is Defined by a Myeloid Differentiation Profile in Acute Myeloid Leukemia. Drugs in R&D. PMID 39316279 DOI: 10.1007/s40268-024-00491-5  0.527
2024 Freda PJ, Ye S, Zhang R, Moore JH, Urbanowicz RJ. Assessing the Limitations of Relief-Based Algorithms in Detecting Higher-Order Interactions. Research Square. PMID 39281873 DOI: 10.21203/rs.3.rs-4870116/v1  0.678
2024 Wong E, Urbanowicz RJ, Bright TJ, Tatonetti NP, Hsiao YW, Huang X, Moore JH, Peng PC. Advancing LGBTQ+ inclusion in STEM education and AI research. Patterns (New York, N.Y.). 5: 101010. PMID 39005486 DOI: 10.1016/j.patter.2024.101010  0.7
2024 Hou B, Wen Z, Bao J, Zhang R, Tong B, Yang S, Wen J, Cui Y, Moore JH, Saykin AJ, Huang H, Thompson PM, Ritchie MD, Davatzikos C, Shen L. Interpretable deep clustering survival machines for Alzheimer's disease subtype discovery. Medical Image Analysis. 97: 103231. PMID 38941858 DOI: 10.1016/j.media.2024.103231  0.558
2024 Hou B, Mondragón A, Tarzanagh DA, Zhou Z, Saykin AJ, Moore JH, Ritchie MD, Long Q, Shen L. PFERM: A Fair Empirical Risk Minimization Approach with Prior Knowledge. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2024: 211-220. PMID 38827072  0.54
2024 Li R, Romano JD, Chen Y, Moore JH. Centralized and Federated Models for the Analysis of Clinical Data. Annual Review of Biomedical Data Science. PMID 38723657 DOI: 10.1146/annurev-biodatasci-122220-115746  0.79
2024 Romano JD, Truong V, Kumar R, Venkatesan M, Graham BE, Hao Y, Matsumoto N, Li X, Wang Z, Ritchie MD, Shen L, Moore JH. The Alzheimer's Knowledge Base: A Knowledge Graph for Alzheimer Disease Research. Journal of Medical Internet Research. 26: e46777. PMID 38635981 DOI: 10.2196/46777  0.775
2024 Li R, Benz L, Duan R, Denny JC, Hakonarson H, Mosley JD, Smoller JW, Wei WQ, Ritchie MD, Moore JH, Chen Y. mixWAS: An efficient distributed algorithm for mixed-outcomes genome-wide association studies. Medrxiv : the Preprint Server For Health Sciences. PMID 38260403 DOI: 10.1101/2024.01.09.24301073  0.821
2024 Li R, Duan R, He L, Moore JH. Risk prediction: Methods, Challenges, and Opportunities. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 29: 650-653. PMID 38160314  0.769
2024 Moore JH, Li X, Chang JH, Tatonetti NP, Theodorescu D, Chen Y, Asselbergs FW, Venkatesan M, Wang ZP. SynTwin: A graph-based approach for predicting clinical outcomes using digital twins derived from synthetic patients. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 29: 96-107. PMID 38160272  0.536
2023 Tong B, Zhou Z, Tarzanagh DA, Hou B, Saykin AJ, Moore J, Ritchie M, Shen L. Class-Balanced Deep Learning with Adaptive Vector Scaling Loss for Dementia Stage Detection. Machine Learning in Medical Imaging. Mlmi (Workshop). 14349: 144-154. PMID 38463442 DOI: 10.1007/978-3-031-45676-3_15  0.545
2023 Tong J, Duan R, Li R, Luo C, Moore JH, Zhu J, Foster GD, Volpp KG, Yancy WS, Shaw PA, Chen Y. Publisher Correction: Quantifying and correcting bias due to outcome dependent self-reported weights in longitudinal study of weight loss interventions. Scientific Reports. 13: 22546. PMID 38110504 DOI: 10.1038/s41598-023-49737-3  0.755
2023 Tong J, Duan R, Li R, Luo C, Moore JH, Zhu J, Foster GD, Volpp KG, Yancy WS, Shaw PA, Chen Y. Quantifying and correcting bias due to outcome dependent self-reported weights in longitudinal study of weight loss interventions. Scientific Reports. 13: 19078. PMID 37925516 DOI: 10.1038/s41598-023-41853-4  0.776
2023 Romano JD, Mei L, Senn J, Moore JH, Mortensen HM. Exploring genetic influences on adverse outcome pathways using heuristic simulation and graph data science. Computational Toxicology (Amsterdam, Netherlands). 25. PMID 37829618 DOI: 10.1016/j.comtox.2023.100261  0.687
2023 Hao Y, Romano JD, Moore JH. Knowledge graph aids comprehensive explanation of drug and chemical toxicity. Cpt: Pharmacometrics & Systems Pharmacology. PMID 37475158 DOI: 10.1002/psp4.12975  0.767
2023 Meyer JG, Urbanowicz RJ, Martin PCN, O'Connor K, Li R, Peng PC, Bright TJ, Tatonetti N, Won KJ, Gonzalez-Hernandez G, Moore JH. ChatGPT and large language models in academia: opportunities and challenges. Biodata Mining. 16: 20. PMID 37443040 DOI: 10.1186/s13040-023-00339-9  0.771
2023 Wang X, Feng Y, Tong B, Bao J, Ritchie MD, Saykin AJ, Moore JH, Urbanowicz R, Shen L. Exploring Automated Machine Learning for Cognitive Outcome Prediction from Multimodal Brain Imaging using STREAMLINE. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2023: 544-553. PMID 37350896  0.729
2023 Tong B, Risacher SL, Bao J, Feng Y, Wang X, Ritchie MD, Moore JH, Urbanowicz R, Saykin AJ, Shen L. Comparing Amyloid Imaging Normalization Strategies for Alzheimer's Disease Classification using an Automated Machine Learning Pipeline. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2023: 525-533. PMID 37350880  0.725
2023 Freda PJ, Ghosh A, Zhang E, Luo T, Chitre AS, Polesskaya O, St Pierre CL, Gao J, Martin CD, Chen H, Garcia-Martinez AG, Wang T, Han W, Ishiwari K, Meyer P, ... ... Moore JH, et al. Automated quantitative trait locus analysis (AutoQTL). Biodata Mining. 16: 14. PMID 37038201 DOI: 10.1186/s13040-023-00331-3  0.809
2023 Singhal P, Veturi Y, Dudek SM, Lucas A, Frase A, van Steen K, Schrodi SJ, Fasel D, Weng C, Pendergrass R, Schaid DJ, Kullo IJ, Dikilitas O, Sleiman PMA, Hakonarson H, ... Moore JH, et al. Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets. American Journal of Human Genetics. 110: 575-591. PMID 37028392 DOI: 10.1016/j.ajhg.2023.03.007  0.761
2023 Freda PJ, Ghosh A, Zhang E, Luo T, Chitre A, Polesskaya O, St Pierre CL, Gao J, Martin CD, Chen H, Garcia-Martinez AG, Wang T, Han W, Ishiwari K, Meyer P, ... ... Moore JH, et al. Automated quantitative trait locus analysis (AutoQTL). Biorxiv : the Preprint Server For Biology. PMID 36711526 DOI: 10.1101/2023.01.12.523835  0.809
2022 Li R, Duan R, He L, Moore JH. Risk prediction: Methods, Challenges, and Opportunities. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 28: 546-548. PMID 36541009  0.777
2022 Hao Y, Romano JD, Moore JH. Knowledge-guided deep learning models of drug toxicity improve interpretation. Patterns (New York, N.Y.). 3: 100565. PMID 36124309 DOI: 10.1016/j.patter.2022.100565  0.752
2022 Woodward AA, Urbanowicz RJ, Naj AC, Moore JH. Genetic heterogeneity: Challenges, impacts, and methods through an associative lens. Genetic Epidemiology. PMID 35924480 DOI: 10.1002/gepi.22497  0.686
2022 Romano JD, Hao Y, Moore JH, Penning TM. Automating Predictive Toxicology Using ComptoxAI. Chemical Research in Toxicology. PMID 35819939 DOI: 10.1021/acs.chemrestox.2c00074  0.764
2022 Weber GM, Hong C, Xia Z, Palmer NP, Avillach P, L'Yi S, Keller MS, Murphy SN, Gutiérrez-Sacristán A, Bonzel CL, Serret-Larmande A, Neuraz A, Omenn GS, Visweswaran S, Klann JG, ... ... Moore JH, et al. International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality. Npj Digital Medicine. 5: 74. PMID 35697747 DOI: 10.1038/s41746-022-00601-0  0.772
2022 Woodward AA, Taylor DM, Goldmuntz E, Mitchell LE, Agopian AJ, Moore JH, Urbanowicz RJ. Gene-Interaction-Sensitive enrichment analysis in congenital heart disease. Biodata Mining. 15: 4. PMID 35151364 DOI: 10.1186/s13040-022-00287-w  0.688
2022 Penrod NM, Moore JH. Antihypertensive effects of yoga in a general patient population: real-world evidence from electronic health records, a retrospective case-control study. Bmc Public Health. 22: 186. PMID 35086500 DOI: 10.1186/s12889-022-12569-3  0.775
2022 Romano JD, Hao Y, Moore JH. Improving QSAR Modeling for Predictive Toxicology using Publicly Aggregated Semantic Graph Data and Graph Neural Networks. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 27: 187-198. PMID 34890148  0.755
2022 Bobak CA, Muse M, Giffin KA, Williamson DA, Greene CS, Moore JH, Wall DP. Human Intrigue: Meta-analysis approaches for big questions with big data while shaking up the peer review process. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 27: 156-162. PMID 34890145  0.626
2021 Hao Y, Moore JH. TargetTox: A Feature Selection Pipeline for Identifying Predictive Targets Associated with Drug Toxicity. Journal of Chemical Information and Modeling. 61: 5386-5394. PMID 34757743 DOI: 10.1021/acs.jcim.1c00733  0.593
2021 Manduchi E, Romano JD, Moore JH. The promise of automated machine learning for the genetic analysis of complex traits. Human Genetics. PMID 34713318 DOI: 10.1007/s00439-021-02393-x  0.675
2021 Romano JD, Le TT, La Cava W, Gregg JT, Goldberg DJ, Chakraborty P, Ray NL, Himmelstein D, Fu W, Moore JH. PMLB v1.0: An open-source dataset collection for benchmarking machine learning methods. Bioinformatics (Oxford, England). PMID 34677586 DOI: 10.1093/bioinformatics/btab727  0.783
2021 Le TT, Gutiérrez-Sacristán A, Son J, Hong C, South AM, Beaulieu-Jones BK, Loh NHW, Luo Y, Morris M, Ngiam KY, Patel LP, Samayamuthu MJ, Schriver E, Tan ALM, Moore J, et al. Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19. Scientific Reports. 11: 20238. PMID 34642371 DOI: 10.1038/s41598-021-99481-9  0.772
2021 Holmes JH, Beinlich J, Boland MR, Bowles KH, Chen Y, Cook TS, Demiris G, Draugelis M, Fluharty L, Gabriel PE, Grundmeier R, Hanson CW, Herman DS, Himes BE, Hubbard RA, ... ... Moore JH, et al. Why Is the Electronic Health Record So Challenging for Research and Clinical Care? Methods of Information in Medicine. PMID 34282602 DOI: 10.1055/s-0041-1731784  0.782
2021 Hall MA, Wallace J, Lucas AM, Bradford Y, Verma SS, Müller-Myhsok B, Passero K, Zhou J, McGuigan J, Jiang B, Pendergrass SA, Zhang Y, Peissig P, Brilliant M, Sleiman P, ... ... Moore JH, et al. Novel EDGE encoding method enhances ability to identify genetic interactions. Plos Genetics. 17: e1009534. PMID 34086673 DOI: 10.1371/journal.pgen.1009534  0.809
2021 Moore JH, Truong VQ, Robbins AB, Nicholson D, Williams-Devane CL. Ten important roles for academic leaders to promote equity, diversity, and inclusion in data science. Biodata Mining. 14: 22. PMID 33785024 DOI: 10.1186/s13040-021-00256-9  0.566
2021 Kim D, Kim JH, Moore JH. Translational Bioinformatics: Integrating Electronic Health Record and Omics Data. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 26: 356-359. PMID 33691034  0.52
2021 Le TT, Gutiérrez-Sacristán A, Son J, Hong C, South AM, Beaulieu-Jones BK, Loh NHW, Luo Y, Morris M, Ngiam KY, Patel LP, Samayamuthu MJ, Schriver E, Tan AL, Moore J, et al. Multinational Prevalence of Neurological Phenotypes in Patients Hospitalized with COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 33655281 DOI: 10.1101/2021.01.27.21249817  0.763
2021 Kohane IS, Aronow BJ, Avillach P, Beaulieu-Jones BK, Bellazzi R, Bradford RL, Brat GA, Cannataro M, Cimino JJ, García-Barrio N, Gehlenborg N, Ghassemi M, Gutiérrez-Sacristán A, Hanauer DA, Holmes JH, ... ... Moore JH, et al. What Every Reader Should Know About Studies Using Electronic Health Record Data but May be Afraid to Ask. Journal of Medical Internet Research. PMID 33600347 DOI: 10.2196/22219  0.793
2021 Klann JG, Weber GM, Estiri H, Moal B, Avillach P, Hong C, Castro V, Maulhardt T, Tan ALM, Geva A, Beaulieu-Jones BK, Malovini A, South AM, Visweswaran S, Omenn GS, ... ... Moore JH, et al. Validation of an Internationally Derived Patient Severity Phenotype to Support COVID-19 Analytics from Electronic Health Record Data. Journal of the American Medical Informatics Association : Jamia. PMID 33566082 DOI: 10.1093/jamia/ocab018  0.781
2021 Weber GM, Hong C, Palmer NP, Avillach P, Murphy SN, Gutiérrez-Sacristán A, Xia Z, Serret-Larmande A, Neuraz A, Omenn GS, Visweswaran S, Klann JG, South AM, Loh NHW, Cannataro M, ... ... Moore JH, et al. International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study. Medrxiv : the Preprint Server For Health Sciences. PMID 33564777 DOI: 10.1101/2020.12.16.20247684  0.766
2021 Li R, Duan R, Zhang X, Lumley T, Pendergrass S, Bauer C, Hakonarson H, Carrell DS, Smoller JW, Wei WQ, Carroll R, Velez Edwards DR, Wiesner G, Sleiman P, Denny JC, ... ... Moore JH, et al. Lossless integration of multiple electronic health records for identifying pleiotropy using summary statistics. Nature Communications. 12: 168. PMID 33420026 DOI: 10.1038/s41467-020-20211-2  0.798
2020 La Cava W, Moore JH. Learning feature spaces for regression with genetic programming. Genetic Programming and Evolvable Machines. 21: 433-467. PMID 33343224 DOI: 10.1007/S10710-020-09383-4  0.328
2020 Romano JD, Moore JH. Ten simple rules for writing a paper about scientific software. Plos Computational Biology. 16: e1008390. PMID 33180774 DOI: 10.1371/journal.pcbi.1008390  0.622
2020 Manduchi E, Fu W, Romano JD, Ruberto S, Moore JH. Embedding covariate adjustments in tree-based automated machine learning for biomedical big data analyses. Bmc Bioinformatics. 21: 430. PMID 32998684 DOI: 10.1186/s12859-020-03755-4  0.655
2020 Brito JJ, Li J, Moore JH, Greene CS, Nogoy NA, Garmire LX, Mangul S. Corrigendum to: Recommendations to enhance rigor and reproducibility in biomedical research. Gigascience. 9. PMID 32940333 DOI: 10.1093/Gigascience/Giaa103  0.637
2020 Brat GA, Weber GM, Gehlenborg N, Avillach P, Palmer NP, Chiovato L, Cimino J, Waitman LR, Omenn GS, Malovini A, Moore JH, Beaulieu-Jones BK, Tibollo V, Murphy SN, Yi SL, et al. International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium. Npj Digital Medicine. 3: 109. PMID 32864472 DOI: 10.1038/s41746-020-00308-0  0.793
2020 Gabryszewski SJ, Chang X, Dudley JW, Mentch F, March M, Holmes JH, Moore J, Grundmeier RW, Hakonarson H, Hill DA. Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories. The Journal of Allergy and Clinical Immunology. PMID 32650023 DOI: 10.1016/J.Jaci.2020.06.026  0.312
2020 Brito JJ, Li J, Moore JH, Greene CS, Nogoy NA, Garmire LX, Mangul S. Recommendations to enhance rigor and reproducibility in biomedical research. Gigascience. 9. PMID 32479592 DOI: 10.1093/Gigascience/Giaa056  0.661
2020 Moore JH, Barnett I, Boland MR, Chen Y, Demiris G, Gonzalez-Hernandez G, Herman DS, Himes BE, Hubbard RA, Kim D, Morris JS, Mowery DL, Ritchie MD, Shen L, Urbanowicz R, et al. Ideas for how informaticians can get involved with COVID-19 research. Biodata Mining. 13: 3. PMID 32419848 DOI: 10.1186/S13040-020-00213-Y  0.777
2020 Li R, Chen Y, Ritchie MD, Moore JH. Electronic health records and polygenic risk scores for predicting disease risk. Nature Reviews. Genetics. PMID 32235907 DOI: 10.1038/S41576-020-0224-1  0.802
2020 Moore JH, Olson RS, Schmitt P, Chen Y, Manduchi E. How Computational Experiments Can Improve Our Understanding of the Genetic Architecture of Common Human Diseases. Artificial Life. 1-15. PMID 32027528 DOI: 10.1162/Artl_A_00308  0.411
2020 Ritchie MD, Moore JH, Kim JH. Translational Bioinformatics: Biobanks in the Precision Medicine Era. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 25: 743-747. PMID 31797645  0.559
2020 Tong J, Duan R, Li R, Scheuemie MJ, Moore JH, Chen Y. Robust-ODAL: Learning from heterogeneous health systems without sharing patient-level data. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 25: 695-706. PMID 31797639  0.792
2020 Liu Y, Huang J, Urbanowicz RJ, Chen K, Manduchi E, Greene CS, Moore JH, Scheet P, Chen Y. Back Cover Image Genetic Epidemiology. 44. DOI: 10.1002/Gepi.22220  0.743
2019 Cava W, Bauer C, Moore JH, Pendergrass SA. Interpretation of machine learning predictions for patient outcomes in electronic health records. Amia ... Annual Symposium Proceedings. Amia Symposium. 2019: 572-581. PMID 32308851  0.766
2019 Yao X, Cong S, Yan J, Risacher SL, Saykin AJ, Moore JH, Shen L. Regional Imaging Genetic Enrichment Analysis. Bioinformatics (Oxford, England). PMID 31860065 DOI: 10.1093/Bioinformatics/Btz948  0.314
2019 Penrod NM, Lynch S, Thomas S, Seshadri N, Moore JH. Prevalence and Characterization of Yoga Mentions in the Electronic Health Record. Journal of the American Board of Family Medicine : Jabfm. 32: 790-800. PMID 31704747 DOI: 10.3122/Jabfm.2019.06.190115  0.766
2019 Orlenko A, Kofink D, Lyytikäinen LP, Nikus K, Mishra P, Kuukasjärvi P, Karhunen PJ, Kähönen M, Laurikka JO, Lehtimäki T, Asselberg FW, Moore JH. Model selection for metabolomics: predicting diagnosis of coronary artery disease using automated machine learning (AutoML). Bioinformatics (Oxford, England). PMID 31702773 DOI: 10.1093/Bioinformatics/Btz796  0.31
2019 Liu Y, Huang J, Urbanowicz RJ, Chen K, Manduchi E, Greene CS, Moore JH, Scheet P, Chen Y. Embracing study heterogeneity for finding genetic interactions in large-scale research consortia. Genetic Epidemiology. PMID 31583758 DOI: 10.1002/Gepi.22262  0.819
2019 Li R, Duan R, Kember RL, Rader DJ, Damrauer SM, Moore JH, Chen Y. A regression framework to uncover pleiotropy in large-scale electronic health record data. Journal of the American Medical Informatics Association : Jamia. 26: 1083-1090. PMID 31529123 DOI: 10.1093/Jamia/Ocz084  0.819
2019 Lo Y, Lynch SF, Urbanowicz RJ, Olson RS, Ritter AZ, Whitehouse CR, O'Connor M, Keim SK, McDonald M, Moore JH, Bowles KH. Using Machine Learning on Home Health Care Assessments to Predict Fall Risk. Studies in Health Technology and Informatics. 264: 684-688. PMID 31438011 DOI: 10.3233/Shti190310  0.656
2019 Huang J, Zhang X, Tong J, Du J, Duan R, Yang L, Moore JH, Tao C, Chen Y. Comparing drug safety of hepatitis C therapies using post-market data. Bmc Medical Informatics and Decision Making. 19: 147. PMID 31391106 DOI: 10.1186/S12911-019-0860-6  0.436
2019 Li R, Chen Y, Moore JH. Integration of genetic and clinical information to improve imputation of data missing from electronic health records. Journal of the American Medical Informatics Association : Jamia. PMID 31329892 DOI: 10.1093/Jamia/Ocz041  0.813
2019 Manduchi E, Orzechowski PR, Ritchie MD, Moore JH. Exploration of a diversity of computational and statistical measures of association for genome-wide genetic studies. Biodata Mining. 12: 14. PMID 31320928 DOI: 10.1186/S13040-019-0201-4  0.646
2019 Orzechowski P, Boryczko K, Moore JH. Scalable biclustering - the future of big data exploration? Gigascience. 8. PMID 31251324 DOI: 10.1093/Gigascience/Giz078  0.307
2019 Le TT, Fu W, Moore JH. Scaling tree-based automated machine learning to biomedical big data with a feature set selector. Bioinformatics (Oxford, England). PMID 31165141 DOI: 10.1093/Bioinformatics/Btz470  0.332
2019 Manduchi E, Hemerich D, van Setten J, Tragante V, Harakalova M, Pei J, Williams SM, van der Harst P, Asselbergs FW, Moore JH. A comparison of two workflows for regulome and transcriptome-based prioritization of genetic variants associated with myocardial mass. Genetic Epidemiology. PMID 31145509 DOI: 10.1002/Gepi.22215  0.38
2019 Penrod NM, Moore JH. Why mind-body medicine is poised to set a new standard for clinical research. Journal of Clinical Epidemiology. PMID 31112802 DOI: 10.1016/J.Jclinepi.2019.05.001  0.766
2019 Van Steen K, Moore JH. How to increase our belief in discovered statistical interactions via large-scale association studies? Human Genetics. PMID 30840129 DOI: 10.1007/S00439-019-01987-W  0.339
2019 Moore JH, Mackay TFC, Williams SM. Testing the assumptions of parametric linear models: the need for biological data mining in disciplines such as human genetics. Biodata Mining. 12: 6. PMID 30792817 DOI: 10.1186/S13040-019-0194-Z  0.343
2019 Moore JH, Boland MR, Camara PG, Chervitz H, Gonzalez G, Himes BE, Kim D, Mowery DL, Ritchie MD, Shen L, Urbanowicz RJ, Holmes JH. Preparing next-generation scientists for biomedical big data: artificial intelligence approaches. Personalized Medicine. PMID 30760118 DOI: 10.2217/Pme-2018-0145  0.795
2019 Orzechowski P, Moore JH. EBIC: an open source software for high-dimensional and big data analyses. Bioinformatics (Oxford, England). PMID 30649199 DOI: 10.1093/Bioinformatics/Btz027  0.315
2019 Wojcieszynski A, La Cava W, Baumann B, Lukens J, Ghiam AF, Urbanowicz R, Swisher-McClure S, Doucette A, Gabriel P, Lin A, Xiao Y, Moore J, Metz J. Machine Learning to Predict Toxicity in Head and Neck Cancer Patients Treated with Definitive Chemoradiation International Journal of Radiation Oncology*Biology*Physics. 105: E139-E140. DOI: 10.1016/J.Ijrobp.2019.06.2182  0.632
2018 Lotterhos KE, Moore JH, Stapleton AE. Analysis validation has been neglected in the Age of Reproducibility. Plos Biology. 16: e3000070. PMID 30532167 DOI: 10.1371/Journal.Pbio.3000070  0.306
2018 Sipper M, Urbanowicz RJ, Moore JH. To know the objective is not (necessarily) to know the objective function. Biodata Mining. 11: 21. PMID 30323861 DOI: 10.1186/S13040-018-0182-8  0.608
2018 Piette ER, Moore JH. Identification of epistatic interactions between the human RNA demethylases FTO and ALKBH5 with gene set enrichment analysis informed by differential methylation. Bmc Proceedings. 12: 59. PMID 30275901 DOI: 10.1186/S12919-018-0122-0  0.814
2018 Le TT, Urbanowicz RJ, Moore JH, McKinney BA. Statistical Inference Relief (STIR) feature selection. Bioinformatics (Oxford, England). PMID 30239600 DOI: 10.1093/Bioinformatics/Bty788  0.662
2018 Urbanowicz RJ, Meeker M, Cava W, Olson RS, Moore JH. Relief-Based Feature Selection: Introduction and Review. Journal of Biomedical Informatics. PMID 30031057 DOI: 10.1016/J.Jbi.2018.07.014  0.67
2018 Urbanowicz RJ, Olson RS, Schmitt P, Meeker M, Moore JH. Benchmarking Relief-Based Feature Selection Methods for Bioinformatics Data Mining. Journal of Biomedical Informatics. PMID 30030120 DOI: 10.1016/J.Jbi.2018.07.015  0.693
2018 Manduchi E, Williams SM, Chesi A, Johnson ME, Wells AD, Grant SFA, Moore JH. Leveraging epigenomics and contactomics data to investigate SNP pairs in GWAS. Human Genetics. PMID 29797095 DOI: 10.1007/S00439-018-1893-0  0.39
2018 Chernikova DA, Madan JC, Housman ML, Zain-Ul-Abideen M, Lundgren SN, Morrison HG, Sogin ML, Williams SM, Moore JH, Karagas MR, Hoen AG. The premature infant gut microbiome during the first 6 weeks of life differs based on gestational maturity at birth. Pediatric Research. PMID 29795209 DOI: 10.1038/S41390-018-0022-Z  0.733
2018 Piette ER, Moore JH. Improving machine learning reproducibility in genetic association studies with proportional instance cross validation (PICV). Biodata Mining. 11: 6. PMID 29713384 DOI: 10.1186/S13040-018-0167-7  0.805
2018 Verma SS, Lucas A, Zhang X, Veturi Y, Dudek S, Li B, Li R, Urbanowicz R, Moore JH, Kim D, Ritchie MD. Collective feature selection to identify crucial epistatic variants. Biodata Mining. 11: 5. PMID 29713383 DOI: 10.1186/S13040-018-0168-6  0.783
2018 Zigon B, Li H, Yao X, Fang S, Hasan MA, Yan J, Moore JH, Saykin AJ, Shen L. GPU Accelerated Browser for Neuroimaging Genomics. Neuroinformatics. PMID 29691798 DOI: 10.1007/S12021-018-9376-Y  0.354
2018 Beaulieu-Jones BK, Lavage DR, Snyder JW, Moore JH, Pendergrass SA, Bauer CR. Characterizing and Managing Missing Structured Data in Electronic Health Records: Data Analysis. Jmir Medical Informatics. 6: e11. PMID 29475824 DOI: 10.2196/Medinform.8960  0.785
2018 Vajravelu RK, Scott FI, Mamtani R, Li H, Moore JH, Lewis JD. Medication class enrichment analysis: a novel algorithm to analyze multiple pharmacologic exposures simultaneously using electronic health record data. Journal of the American Medical Informatics Association : Jamia. PMID 29378062 DOI: 10.1093/Jamia/Ocx162  0.3
2018 Manduchi E, Chesi A, Hall MA, Grant SFA, Moore JH. Leveraging putative enhancer-promoter interactions to investigate two-way epistasis in Type 2 Diabetes GWAS. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 23: 548-558. PMID 29218913  0.687
2018 Beaulieu-Jones BK, Orzechowski P, Moore JH. Mapping Patient Trajectories using Longitudinal Extraction and Deep Learning in the MIMIC-III Critical Care Database. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 23: 123-132. PMID 29218875  0.777
2017 Huang J, Zhang X, Du J, Duan R, Yang L, Moore JH, Chen Y, Tao C. Comparing Different Adverse Effects Among Multiple Drugs Using FAERS Data. Studies in Health Technology and Informatics. 245: 1268. PMID 29295353  0.361
2017 Olson RS, La Cava W, Orzechowski P, Urbanowicz RJ, Moore JH. PMLB: a large benchmark suite for machine learning evaluation and comparison. Biodata Mining. 10: 36. PMID 29238404 DOI: 10.1186/S13040-017-0154-4  0.66
2017 Skarke C, Lahens NF, Rhoades SD, Campbell A, Bittinger K, Bailey A, Hoffmann C, Olson RS, Chen L, Yang G, Price TS, Moore JH, Bushman FD, Greene CS, Grant GR, et al. A Pilot Characterization of the Human Chronobiome. Scientific Reports. 7: 17141. PMID 29215023 DOI: 10.1038/S41598-017-17362-6  0.667
2017 Huang J, Liu Y, Vitale S, Penning TM, Whitehead AS, Blair IA, Vachani A, Clapper ML, Muscat JE, Lazarus P, Scheet P, Moore JH, Chen Y. On meta- and mega-analyses for gene-environment interactions. Genetic Epidemiology. PMID 29110346 DOI: 10.1002/Gepi.22085  0.373
2017 Hall MA, Wallace J, Lucas A, Kim D, Basile AO, Verma SS, McCarty CA, Brilliant MH, Peissig PL, Kitchner TE, Verma A, Pendergrass SA, Dudek SM, Moore JH, Ritchie MD. PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies. Nature Communications. 8: 1167. PMID 29079728 DOI: 10.1038/S41467-017-00802-2  0.807
2017 Cole BS, Hall MA, Urbanowicz RJ, Gilbert-Diamond D, Moore JH. Analysis of Gene-Gene Interactions. Current Protocols in Human Genetics. 95: 1.14.1-1.14.10. PMID 29044470 DOI: 10.1002/Cphg.45  0.817
2017 Wang L, Damrauer SM, Zhang H, Zhang AX, Xiao R, Moore JH, Chen J. Phenotype validation in electronic health records based genetic association studies. Genetic Epidemiology. PMID 29023970 DOI: 10.1002/Gepi.22080  0.396
2017 Ritchie MD, Davis JR, Aschard H, Battle A, Conti D, Du M, Eskin E, Fallin MD, Hsu L, Kraft P, Moore JH, Pierce BL, Bien SA, Thomas DC, Wei P, et al. Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions. American Journal of Epidemiology. 186: 771-777. PMID 28978191 DOI: 10.1093/Aje/Kwx229  0.657
2017 Mechanic LE, Lindström S, Daily KM, Sieberts SK, Amos CI, Chen HS, Cox NJ, Dathe M, Feuer EJ, Guertin MJ, Hoffman J, Liu Y, Moore JH, Myers CL, Ritchie MD, et al. Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology. Plos Genetics. 13: e1006945. PMID 28957327 DOI: 10.1371/Journal.Pgen.1006945  0.577
2017 Graham BE, Darabos C, Huang M, Muglia LJ, Moore JH, Williams SM. Evolutionarily derived networks to inform disease pathways. Genetic Epidemiology. PMID 28944497 DOI: 10.1002/Gepi.22078  0.737
2017 Denaxas S, Direk K, Gonzalez-Izquierdo A, Pikoula M, Cakiroglu A, Moore J, Hemingway H, Smeeth L. Methods for enhancing the reproducibility of biomedical research findings using electronic health records. Biodata Mining. 10: 31. PMID 28912836 DOI: 10.1186/S13040-017-0151-7  0.304
2017 Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, Dale C, Dudek S, Furlong CE, Gaunt TR, Kim DS, ... ... Moore JH, et al. Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals. Biodata Mining. 10: 25. PMID 28770004 DOI: 10.1186/S13040-017-0145-5  0.776
2017 Yao X, Yan J, Liu K, Kim S, Nho K, Risacher SL, Greene CS, Moore JH, Saykin AJ, Shen L. Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules. Bioinformatics (Oxford, England). PMID 28575147 DOI: 10.1093/Bioinformatics/Btx344  0.683
2017 Moore JH, Andrews PC, Olson RS, Carlson SE, Larock CR, Bulhoes MJ, O'Connor JP, Greytak EM, Armentrout SL. Grid-based stochastic search for hierarchical gene-gene interactions in population-based genetic studies of common human diseases. Biodata Mining. 10: 19. PMID 28572842 DOI: 10.1186/S13040-017-0139-3  0.453
2017 Tragante V, Gho JMIH, Felix JF, Vasan RS, Smith NL, Voight BF, Palmer C, van der Harst P, Moore JH, Asselbergs FW. Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype. Biodata Mining. 10: 18. PMID 28559929 DOI: 10.1186/S13040-017-0137-5  0.41
2017 Kodaman N, Sobota RS, Asselbergs FW, Oetjens MT, Moore JH, Brown NJ, Aldrich MC, Williams SM. Genetic Effects on the Correlation Structure of CVD Risk Factors: Exome-Wide Data From a Ghanaian Population. Global Heart. PMID 28408189 DOI: 10.1016/J.Gheart.2017.01.013  0.316
2017 Ahmed M, Sallari RC, Guo H, Moore JH, He HH, Lupien M. Variant Set Enrichment: an R package to identify disease-associated functional genomic regions. Biodata Mining. 10: 9. PMID 28239419 DOI: 10.1186/S13040-017-0129-5  0.345
2016 Cheng S, Andrew AS, Andrews PC, Moore JH. Complex systems analysis of bladder cancer susceptibility reveals a role for decarboxylase activity in two genome-wide association studies. Biodata Mining. 9: 40. PMID 27999618 DOI: 10.1186/S13040-016-0119-Z  0.404
2016 Moore JH, Jennings SF, Greene CS, Hunter LE, Perkins AD, Williams-Devane C, Wunsch DC, Zhao Z, Huang X. NO-BOUNDARY THINKING IN BIOINFORMATICS. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 22: 646-648. PMID 27897015  0.591
2016 Beaulieu-Jones BK, Moore JH. MISSING DATA IMPUTATION IN THE ELECTRONIC HEALTH RECORD USING DEEPLY LEARNED AUTOENCODERS. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 22: 207-218. PMID 27896976  0.796
2016 De R, Verma SS, Holzinger E, Hall M, Burt A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Lange LA, Lanktree MB, Larson EB, North KE, Reiner AP, ... ... Moore JH, et al. Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts. Human Genetics. PMID 27848076 DOI: 10.1007/S00439-016-1738-7  0.797
2016 Yao X, Yan J, Kim S, Nho K, Risacher SL, Inlow M, Moore JH, Saykin AJ, Shen L. Two-dimensional enrichment analysis for mining high-level imaging genetic associations. Brain Informatics. PMID 27747820 DOI: 10.1007/S40708-016-0052-4  0.403
2016 Denaxas SC, Asselbergs FW, Moore JH. The tip of the iceberg: challenges of accessing hospital electronic health record data for biological data mining. Biodata Mining. 9: 29. PMID 27688810 DOI: 10.1186/S13040-016-0109-1  0.324
2016 Frost HR, Shen L, Saykin AJ, Williams SM, Moore JH. Identifying significant gene-environment interactions using a combination of screening testing and hierarchical false discovery rate control. Genetic Epidemiology. PMID 27578615 DOI: 10.1002/Gepi.21997  0.737
2016 Li H, Achour I, Bastarache L, Berghout J, Gardeux V, Li J, Lee Y, Pesce L, Yang X, Ramos KS, Foster I, Denny JC, Moore JH, Lussier YA. Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions. Npj Genomic Medicine. 1. PMID 27482468 DOI: 10.1038/Npjgenmed.2016.6  0.386
2016 Wei R, De Vivo I, Huang S, Zhu X, Risch H, Moore JH, Yu H, Garmire LX. Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer. Oncotarget. PMID 27409342 DOI: 10.18632/Oncotarget.10509  0.327
2016 Hall MA, Moore JH, Ritchie MD. Embracing Complex Associations in Common Traits: Critical Considerations for Precision Medicine. Trends in Genetics : Tig. PMID 27392675 DOI: 10.1016/J.Tig.2016.06.001  0.807
2016 Frost HR, Amos CI, Moore JH. A global test for gene-gene interactions based on random matrix theory. Genetic Epidemiology. PMID 27386793 DOI: 10.1002/Gepi.21990  0.727
2016 Qiu J, Moore JH, Darabos C. Studying the Genetics of Complex Disease With Ancestry-Specific Human Phenotype Networks: The Case of Type 2 Diabetes in East Asian Populations. Genetic Epidemiology. PMID 27061195 DOI: 10.1002/Gepi.21964  0.757
2016 Li J, Malley JD, Andrew AS, Karagas MR, Moore JH. Detecting gene-gene interactions using a permutation-based random forest method. Biodata Mining. 9: 14. PMID 27053949 DOI: 10.1186/S13040-016-0093-5  0.416
2016 Huang M, Graham BE, Zhang G, Harder R, Kodaman N, Moore JH, Muglia L, Williams SM. Evolutionary triangulation: informing genetic association studies with evolutionary evidence. Biodata Mining. 9: 12. PMID 27042214 DOI: 10.1186/S13040-016-0091-7  0.357
2016 Himmelstein DS, Greene CS, Moore JH. Erratum to: Evolving hard problems: generating human genetics datasets with a complex etiology. Biodata Mining. 9: 9. PMID 26848312 DOI: 10.1186/S13040-016-0085-5  0.787
2016 Darabos C, Qiu J, Moore JH. AN INTEGRATED NETWORK APPROACH TO IDENTIFYING BIOLOGICAL PATHWAYS AND ENVIRONMENTAL EXPOSURE INTERACTIONS IN COMPLEX DISEASES. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 21: 9-20. PMID 26776169  0.723
2016 Lynch SM, Moore JH. A call for biological data mining approaches in epidemiology. Biodata Mining. 9: 1. PMID 26734074 DOI: 10.1186/S13040-015-0079-8  0.411
2015 De R, Hu T, Moore JH, Gilbert-Diamond D. Characterizing gene-gene interactions in a statistical epistasis network of twelve candidate genes for obesity. Biodata Mining. 8: 45. PMID 26715945 DOI: 10.1186/S13040-015-0077-X  0.752
2015 Fan R, Wang Y, Chiu CY, Chen W, Ren H, Li Y, Boehnke M, Amos CI, Moore JH, Xiong M. Meta-analysis of Complex Diseases at Gene Level by Generalized Functional Linear Models. Genetics. PMID 26715663 DOI: 10.1534/Genetics.115.180869  0.406
2015 Hu T, Andrew AS, Karagas MR, Moore JH. Functional dyadicity and heterophilicity of gene-gene interactions in statistical epistasis networks. Biodata Mining. 8: 43. PMID 26697115 DOI: 10.1186/S13040-015-0062-4  0.412
2015 De R, Verma SS, Drenos F, Holzinger ER, Holmes MV, Hall MA, Crosslin DR, Carrell DS, Hakonarson H, Jarvik G, Larson E, Pacheco JA, Rasmussen-Torvik LJ, Moore CB, Asselbergs FW, ... Moore JH, et al. Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR). Biodata Mining. 8: 41. PMID 26674805 DOI: 10.1186/S13040-015-0074-0  0.782
2015 Lishout FV, Gadaleta F, Moore JH, Wehenkel L, Steen KV. gammaMAXT: a fast multiple-testing correction algorithm. Biodata Mining. 8: 36. PMID 26594243 DOI: 10.1186/S13040-015-0069-X  0.33
2015 Keating BJ, Setten Jv, Jacobson PA, Holmes MV, Verma SS, Chandrupatla HR, Nair N, Gao H, Li YR, Chang B, Wong C, Phillips R, Cole BS, Mukhtar E, Zhang W, ... ... Moore JH, et al. Design and Implementation of the International Genetics and Translational Research in Transplantation Network Transplantation. 99: 2401-2412. PMID 26479416 DOI: 10.1097/Tp.0000000000000913  0.719
2015 Frost HR, Li Z, Asselbergs FW, Moore JH. An Independent Filter for Gene Set Testing Based on Spectral Enrichment. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 12: 1076-86. PMID 26451820 DOI: 10.1109/Tcbb.2015.2415815  0.71
2015 Urbanowicz RJ, Moore JH. ExSTraCS 2.0: Description and Evaluation of a Scalable Learning Classifier System. Evolutionary Intelligence. 8: 89-116. PMID 26417393 DOI: 10.1007/S12065-015-0128-8  0.679
2015 Mackay TF, Moore JH. Erratum to: Why epistasis is important for tackling complex human disease genetics. Genome Medicine. 7: 85. PMID 26343148 DOI: 10.1186/S13073-015-0205-8  0.332
2015 White MJ, Kodaman NM, Harder RH, Asselbergs FW, Vaughan DE, Brown NJ, Moore JH, Williams SM. Genetics of Plasminogen Activator Inhibitor-1 (PAI-1) in a Ghanaian Population. Plos One. 10: e0136379. PMID 26322636 DOI: 10.1371/Journal.Pone.0136379  0.391
2015 Siwo GH, Williams SM, Moore JH. Erratum to: The future of genomic medicine education in Africa. Genome Medicine. 7: 70. PMID 26321605 DOI: 10.1186/S13073-015-0193-8  0.714
2015 Frost HR, Li Z, Moore JH. Principal component gene set enrichment (PCGSE). Biodata Mining. 8: 25. PMID 26300978 DOI: 10.1186/S13040-015-0059-Z  0.719
2015 Siwo GH, Williams SM, Moore JH. The future of genomic medicine education in Africa. Genome Medicine. 7: 47. PMID 26246857 DOI: 10.1186/S13073-015-0175-X  0.742
2015 Weiss TL, Zieselman A, Hill DP, Diamond SG, Shen L, Saykin AJ, Moore JH. The role of visualization and 3-D printing in biological data mining. Biodata Mining. 8: 22. PMID 26246856 DOI: 10.1186/S13040-015-0056-2  0.329
2015 Gui J, Greene CS, Sullivan C, Taylor W, Moore JH, Kim C. Testing multiple hypotheses through IMP weighted FDR based on a genetic functional network with application to a new zebrafish transcriptome study. Biodata Mining. 8: 17. PMID 26097506 DOI: 10.1186/S13040-015-0050-8  0.691
2015 Williams SM, Moore JH. Lumping versus splitting: the need for biological data mining in precision medicine. Biodata Mining. 8: 16. PMID 26085842 DOI: 10.1186/S13040-015-0049-1  0.35
2015 Frost HR, Li Z, Moore JH. Spectral gene set enrichment (SGSE). Bmc Bioinformatics. 16: 70. PMID 25879888 DOI: 10.1186/S12859-015-0490-7  0.71
2015 Yan J, Kim S, Nho K, Chen R, Risacher SL, Moore JH, Saykin AJ, Shen L. Hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in Alzheimer's disease. Frontiers in Genetics. 6: 117. PMID 25859259 DOI: 10.3389/Fgene.2015.00117  0.319
2015 Greene AC, Giffin KA, Greene CS, Moore JH. Adapting bioinformatics curricula for big data. Briefings in Bioinformatics. PMID 25829469 DOI: 10.1093/Bib/Bbv018  0.682
2015 Beaulieu-Jones BR, O'Brien DM, Hopkins SE, Moore JH, Boyer BB, Gilbert-Diamond D. Sex, Adiposity, and Hypertension Status Modify the Inverse Effect of Marine Food Intake on Blood Pressure in Alaska Native (Yup'ik) People. The Journal of Nutrition. 145: 931-8. PMID 25788581 DOI: 10.3945/Jn.114.209619  0.554
2015 Ma S, Johnson D, Ashby C, Xiong D, Cramer CL, Moore JH, Zhang S, Huang X. SPARCoC: a new framework for molecular pattern discovery and cancer gene identification. Plos One. 10: e0117135. PMID 25768286 DOI: 10.1371/Journal.Pone.0117135  0.338
2015 White MJ, Eren F, A??rba?l? D, Chen J, Hu T, Moore JH, Williams SM, A??rba?l? M. A systems genetics approach to dyslipidemia in children and adolescents. Omics : a Journal of Integrative Biology. 19: 248-59. PMID 25671407 DOI: 10.1089/Omi.2014.0140  0.333
2015 Pattin KA, Greene AC, Altman RB, Cohen KB, Wethington E, Görg C, Hunter LE, Muse SV, Radivojac P, Moore JH. Training the next generation of quantitative biologists in the era of big data. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 488-92. PMID 25592609  0.766
2015 Hu T, Darabos C, Cricco ME, Kong E, Moore JH. Genome-wide genetic interaction analysis of glaucoma using expert knowledge derived from human phenotype networks. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 207-18. PMID 25592582  0.749
2015 Frost HR, Andrew AS, Karagas MR, Moore JH. A screening-testing approach for detecting gene-environment interactions using sequential penalized and unpenalized multiple logistic regression. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 183-94. PMID 25592580  0.692
2015 Darabos C, Grussing ED, Cricco ME, Clark KA, Moore JH. A bipartite network approach to inferring interactions between environmental exposures and human diseases. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 171-82. PMID 25592579  0.706
2015 Moore JH. The critical need for computational methods and software for simulating complex genetic and genomic data. Genetic Epidemiology. 39: 1. PMID 25476032 DOI: 10.1002/Gepi.21878  0.373
2015 Moore JH, Hill DP. Epistasis analysis using artificial intelligence. Methods in Molecular Biology (Clifton, N.J.). 1253: 327-46. PMID 25403541 DOI: 10.1007/978-1-4939-2155-3_18  0.38
2015 Moore JH. Epistasis analysis using ReliefF. Methods in Molecular Biology (Clifton, N.J.). 1253: 315-25. PMID 25403540 DOI: 10.1007/978-1-4939-2155-3_17  0.374
2015 Moore JH, Andrews PC. Epistasis analysis using multifactor dimensionality reduction. Methods in Molecular Biology (Clifton, N.J.). 1253: 301-14. PMID 25403539 DOI: 10.1007/978-1-4939-2155-3_16  0.334
2015 Darabos C, Moore JH. Genome-wide epistasis and pleiotropy characterized by the bipartite human phenotype network. Methods in Molecular Biology (Clifton, N.J.). 1253: 269-83. PMID 25403537 DOI: 10.1007/978-1-4939-2155-3_14  0.762
2015 Moore JH, Hu T. Epistasis analysis using information theory. Methods in Molecular Biology (Clifton, N.J.). 1253: 257-68. PMID 25403536 DOI: 10.1007/978-1-4939-2155-3_13  0.334
2015 Moore JH, Amos R, Kiralis J, Andrews PC. Heuristic identification of biological architectures for simulating complex hierarchical genetic interactions. Genetic Epidemiology. 39: 25-34. PMID 25395175 DOI: 10.1002/Gepi.21865  0.394
2015 Chen HS, Hutter CM, Mechanic LE, Amos CI, Bafna V, Hauser ER, Hernandez RD, Li C, Liberles DA, McAllister K, Moore JH, Paltoo DN, Papanicolaou GJ, Peng B, Ritchie MD, et al. Genetic simulation tools for post-genome wide association studies of complex diseases. Genetic Epidemiology. 39: 11-9. PMID 25371374 DOI: 10.1002/Gepi.21870  0.648
2015 Andrew AS, Gui J, Hu T, Wyszynski A, Marsit CJ, Kelsey KT, Schned AR, Tanyos SA, Pendleton EM, Ekstrom RM, Li Z, Zens MS, Borsuk M, Moore JH, Karagas MR. Genetic polymorphisms modify bladder cancer recurrence and survival in a USA population-based prognostic study. Bju International. 115: 238-47. PMID 24666523 DOI: 10.1111/Bju.12641  0.308
2014 Pouladi N, Cowper-Sallari R, Moore JH. Combining functional genomics strategies identifies modular heterogeneity of breast cancer intrinsic subtypes. Biodata Mining. 7: 27. PMID 25745517 DOI: 10.1186/1756-0381-7-27  0.739
2014 Chernikova DA, Koestler DC, Hoen AG, Housman ML, Hibberd PL, Moore JH, Morrison HG, Sogin ML, Zain-Ul-Abideen M, Madan JC. Fetal exposures and perinatal influences on the stool microbiota of premature infants. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 1-7. PMID 25394613 DOI: 10.3109/14767058.2014.987748  0.736
2014 Lekman M, Hössjer O, Andrews P, Källberg H, Uvehag D, Charney D, Manji H, Rush JA, McMahon FJ, Moore JH, Kockum I. The genetic interacting landscape of 63 candidate genes in Major Depressive Disorder: an explorative study. Biodata Mining. 7: 19. PMID 25279001 DOI: 10.1186/1756-0381-7-19  0.406
2014 Gorlov IP, Moore JH, Peng B, Jin JL, Gorlova OY, Amos CI. SNP characteristics predict replication success in association studies. Human Genetics. 133: 1477-86. PMID 25273843 DOI: 10.1007/S00439-014-1493-6  0.315
2014 Davis MA, Gilbert-Diamond D, Karagas MR, Li Z, Moore JH, Williams SM, Frost HR. A dietary-wide association study (DWAS) of environmental metal exposure in US children and adults. Plos One. 9: e104768. PMID 25198543 DOI: 10.1371/Journal.Pone.0104768  0.744
2014 Zieselman AL, Fisher JM, Hu T, Andrews PC, Greene CS, Shen L, Saykin AJ, Moore JH. Computational genetics analysis of grey matter density in Alzheimer's disease. Biodata Mining. 7: 17. PMID 25165488 DOI: 10.1186/1756-0381-7-17  0.71
2014 Yan J, Du L, Kim S, Risacher SL, Huang H, Moore JH, Saykin AJ, Shen L. Transcriptome-guided amyloid imaging genetic analysis via a novel structured sparse learning algorithm. Bioinformatics (Oxford, England). 30: i564-71. PMID 25161248 DOI: 10.1093/Bioinformatics/Btu465  0.384
2014 Hu T, Banzhaf W, Moore JH. The effects of recombination on phenotypic exploration and robustness in evolution. Artificial Life. 20: 457-70. PMID 25148550 DOI: 10.1162/Artl_A_00145  0.361
2014 Pechenick DA, Payne JL, Moore JH. Phenotypic robustness and the assortativity signature of human transcription factor networks. Plos Computational Biology. 10: e1003780. PMID 25121490 DOI: 10.1371/Journal.Pcbi.1003780  0.804
2014 Penrod NM, Moore JH. Data science approaches to pharmacogenetics. Current Molecular Medicine. 14: 805-13. PMID 25109795 DOI: 10.2174/1566524014666140811112438  0.81
2014 Malley JD, Moore JH. First complex, then simple. Biodata Mining. 7: 13. PMID 25076985 DOI: 10.1186/1756-0381-7-13  0.329
2014 Ciesielski TH, Pendergrass SA, White MJ, Kodaman N, Sobota RS, Huang M, Bartlett J, Li J, Pan Q, Gui J, Selleck SB, Amos CI, Ritchie MD, Moore JH, Williams SM. Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors. Biodata Mining. 7: 10. PMID 25071867 DOI: 10.1186/1756-0381-7-10  0.813
2014 Urbanowicz RJ, Granizo-Mackenzie AL, Kiralis J, Moore JH. A classification and characterization of two-locus, pure, strict, epistatic models for simulation and detection. Biodata Mining. 7: 8. PMID 25057293 DOI: 10.1186/1756-0381-7-8  0.697
2014 Mackay TF, Moore JH. Why epistasis is important for tackling complex human disease genetics. Genome Medicine. 6: 42. PMID 25031624 DOI: 10.1186/Gm561  0.336
2014 Penrod NM, Greene CS, Moore JH. Predicting targeted drug combinations based on Pareto optimal patterns of coexpression network connectivity. Genome Medicine. 6: 33. PMID 24944582 DOI: 10.1186/Gm550  0.771
2014 White MJ, Tacconelli A, Chen JS, Wejse C, Hill PC, Gomes VF, Velez-Edwards DR, Østergaard LJ, Hu T, Moore JH, Novelli G, Scott WK, Williams SM, Sirugo G. Epiregulin (EREG) and human V-ATPase (TCIRG1): genetic variation, ethnicity and pulmonary tuberculosis susceptibility in Guinea-Bissau and The Gambia. Genes and Immunity. 15: 370-7. PMID 24898387 DOI: 10.1038/Gene.2014.28  0.376
2014 De R, Bush WS, Moore JH. Bioinformatics challenges in genome-wide association studies (GWAS). Methods in Molecular Biology (Clifton, N.J.). 1168: 63-81. PMID 24870131 DOI: 10.1007/978-1-4939-0847-9_5  0.746
2014 Greene CS, Tan J, Ung M, Moore JH, Cheng C. Big data bioinformatics. Journal of Cellular Physiology. 229: 1896-900. PMID 24799088 DOI: 10.1002/Jcp.24662  0.726
2014 Hu T, Pan Q, Andrew AS, Langer JM, Cole MD, Tomlinson CR, Karagas MR, Moore JH. Functional genomics annotation of a statistical epistasis network associated with bladder cancer susceptibility. Biodata Mining. 7: 5. PMID 24725556 DOI: 10.1186/1756-0381-7-5  0.664
2014 Vimaleswaran KS, Cavadino A, Berry DJ, Mangino M, Andrews P, Moore JH, Spector TD, Power C, Järvelin MR, Hyppönen E. Interaction between allelic variations in vitamin D receptor and retinoid X receptor genes on metabolic traits. Bmc Genetics. 15: 37. PMID 24641809 DOI: 10.1186/1471-2156-15-37  0.34
2014 Frost HR, Moore JH. Optimization of gene set annotations via entropy minimization over variable clusters (EMVC). Bioinformatics (Oxford, England). 30: 1698-706. PMID 24574114 DOI: 10.1093/Bioinformatics/Btu110  0.709
2014 Pan Q, Hu T, Malley JD, Andrew AS, Karagas MR, Moore JH. A system-level pathway-phenotype association analysis using synthetic feature random forest. Genetic Epidemiology. 38: 209-19. PMID 24535726 DOI: 10.1002/Gepi.21794  0.663
2014 Penrod NM, Moore JH. Influence networks based on coexpression improve drug target discovery for the development of novel cancer therapeutics. Bmc Systems Biology. 8: 12. PMID 24495353 DOI: 10.1186/1752-0509-8-12  0.776
2014 Darabos C, White MJ, Graham BE, Leung DN, Williams SM, Moore JH. The multiscale backbone of the human phenotype network based on biological pathways. Biodata Mining. 7: 1. PMID 24460644 DOI: 10.1186/1756-0381-7-1  0.745
2014 Pattin KA, Greene AC, Altman RB, Hunter LE, Ross DA, Foster JA, Moore JH. Building the next generation of quantitative biologists. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 417-21. PMID 24297567  0.761
2014 Cheng C, Moore J, Greene C. Applications of bioinformatics to non-coding RNAs in the era of next-generation sequencing. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 412-6. PMID 24297566  0.592
2014 Darabos C, Harmon SH, Moore JH. Using the bipartite human phenotype network to reveal pleiotropy and epistasis beyond the gene. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 188-99. PMID 24297546  0.749
2014 Shen L, Thompson PM, Potkin SG, Bertram L, Farrer LA, Foroud TM, Green RC, Hu X, Huentelman MJ, Kim S, Kauwe JS, Li Q, Liu E, Macciardi F, Moore JH, et al. Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers. Brain Imaging and Behavior. 8: 183-207. PMID 24092460 DOI: 10.1007/S11682-013-9262-Z  0.403
2014 Payne JL, Moore JH, Wagner A. Robustness, evolvability, and the logic of genetic regulation. Artificial Life. 20: 111-26. PMID 23373974 DOI: 10.1162/Artl_A_00099  0.319
2014 Yao X, Chen R, Kim S, Yan J, Du L, Nho KT, Foroud T, Moore J, Weiner MW, Saykin AJ, Shen L. Genetic Findings Using Adni Multimodal Quantitative Phenotypes: A Review Of Papers Published In 2013 Alzheimers & Dementia. 10: 351. DOI: 10.1016/J.Jalz.2014.05.184  0.314
2014 Yan J, Kim S, Nho KT, Risacher SL, Moore J, Saykin AJ, Shen L. Effects Of Newly Identified Top Ad Candidate Genes On Memory Performance: Snp, Gene, And Epistasis Analyses In Adni Alzheimers & Dementia. 10: 388. DOI: 10.1016/J.Jalz.2014.05.180  0.306
2013 Rudd J, Moore JH, Urbanowicz RJ. A Multi-Core Parallelization Strategy for Statistical Significance Testing in Learning Classifier Systems. Evolutionary Intelligence. 6. PMID 24358057 DOI: 10.1007/S12065-013-0092-0  0.697
2013 Williams SM, Moore JH. Big Data analysis on autopilot? Biodata Mining. 6: 22. PMID 24314297 DOI: 10.1186/1756-0381-6-22  0.331
2013 Franceschini N, Fox E, Zhang Z, Edwards TL, Nalls MA, Sung YJ, Tayo BO, Sun YV, Gottesman O, Adeyemo A, Johnson AD, Young JH, Rice K, Duan Q, Chen F, ... ... Moore JH, et al. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. American Journal of Human Genetics. 93: 545-54. PMID 23972371 DOI: 10.1016/J.Ajhg.2013.07.010  0.542
2013 Moore JH, Ritchie MD. The central role of biological data mining in connecting diverse disciplines. Biodata Mining. 6: 14. PMID 23937773 DOI: 10.1186/1756-0381-6-14  0.574
2013 Malley JD, Moore JH. The disconnect between classical biostatistics and the biological data mining community. Biodata Mining. 6: 12. PMID 23880104 DOI: 10.1186/1756-0381-6-12  0.333
2013 Penrod NM, Moore JH. Key genes for modulating information flow play a temporal role as breast tumor coexpression networks are dynamically rewired by letrozole. Bmc Medical Genomics. 6: S2. PMID 23819860 DOI: 10.1186/1755-8794-6-S2-S2  0.777
2013 Gui J, Moore JH, Williams SM, Andrews P, Hillege HL, van der Harst P, Navis G, Van Gilst WH, Asselbergs FW, Gilbert-Diamond D. A Simple and Computationally Efficient Approach to Multifactor Dimensionality Reduction Analysis of Gene-Gene Interactions for Quantitative Traits. Plos One. 8: e66545. PMID 23805232 DOI: 10.1371/Journal.Pone.0066545  0.664
2013 Pan Q, Hu T, Moore JH. Epistasis, complexity, and multifactor dimensionality reduction. Methods in Molecular Biology (Clifton, N.J.). 1019: 465-77. PMID 23756906 DOI: 10.1007/978-1-62703-447-0_22  0.666
2013 Tsongalis GJ, Chao E, Hagenkord JM, Hambuch T, Moore JH. Bioinformatics: what the clinical laboratorian needs to know and prepare for. Clinical Chemistry. 59: 1301-5. PMID 23723312 DOI: 10.1373/Clinchem.2012.198226  0.358
2013 Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, ... ... Moore JH, et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nature Genetics. 45: 690-6. PMID 23583978 DOI: 10.1038/Ng.2608  0.524
2013 Pechenick DA, Moore JH, Payne JL. The influence of assortativity on the robustness and evolvability of gene regulatory networks upon gene birth. Journal of Theoretical Biology. 330: 26-36. PMID 23542384 DOI: 10.1016/J.Jtbi.2013.03.019  0.806
2013 Hu T, Chen Y, Kiralis JW, Moore JH. ViSEN: methodology and software for visualization of statistical epistasis networks. Genetic Epidemiology. 37: 283-5. PMID 23468157 DOI: 10.1002/Gepi.21718  0.382
2013 Urbanowicz RJ, Andrew AS, Karagas MR, Moore JH. Role of genetic heterogeneity and epistasis in bladder cancer susceptibility and outcome: a learning classifier system approach. Journal of the American Medical Informatics Association : Jamia. 20: 603-12. PMID 23444013 DOI: 10.1136/Amiajnl-2012-001574  0.705
2013 Molineros JE, Maiti AK, Sun C, Looger LL, Han S, Kim-Howard X, Glenn S, Adler A, Kelly JA, Niewold TB, Gilkeson GS, Brown EE, Alarcón GS, Edberg JC, Petri M, ... ... Moore JH, et al. Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. Plos Genetics. 9: e1003222. PMID 23441136 DOI: 10.1371/Journal.Pgen.1003222  0.346
2013 Collins RL, Hu T, Wejse C, Sirugo G, Williams SM, Moore JH. Multifactor dimensionality reduction reveals a three-locus epistatic interaction associated with susceptibility to pulmonary tuberculosis. Biodata Mining. 6: 4. PMID 23418869 DOI: 10.1186/1756-0381-6-4  0.351
2013 Hoen AG, Gardner SN, Moore JH. Identification of SNPs associated with variola virus virulence. Biodata Mining. 6: 3. PMID 23410064 DOI: 10.1186/1756-0381-6-3  0.337
2013 Hu T, Chen Y, Kiralis JW, Collins RL, Wejse C, Sirugo G, Williams SM, Moore JH. An information-gain approach to detecting three-way epistatic interactions in genetic association studies. Journal of the American Medical Informatics Association : Jamia. 20: 630-6. PMID 23396514 DOI: 10.1136/Amiajnl-2012-001525  0.431
2013 Fung E, Patsopoulos NA, Belknap SM, O'Rourke DJ, Robb JF, Anderson JL, Shworak NW, Moore JH. Erratum: Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin (Thrombosis and Hemostasis 38:8 (900)) Seminars in Thrombosis and Hemostasis. 39. DOI: 10.1055/S-0032-1333535  0.335
2013 Yan J, Kim S, Nho K, Chen R, Risacher S, Moore J, Saykin A, Shen L. Hippocampal transcriptome-guided gene-gene interaction of memory phenotype in MCI and Alzheimer’s disease Alzheimers & Dementia. 9: 4. DOI: 10.1016/J.Jalz.2013.04.018  0.309
2012 Urbanowicz RJ, Granizo-Mackenzie A, Moore JH. An Analysis Pipeline with Statistical and Visualization-Guided Knowledge Discovery for Michigan-Style Learning Classifier Systems. Ieee Computational Intelligence Magazine. 7: 35-45. PMID 25431544 DOI: 10.1109/Mci.2012.2215124  0.691
2012 Sloan CD, Andrew AS, Gruber JF, Mwenda KM, Moore JH, Onega T, Karagas MR, Shi X, Duell EJ. Indoor and Outdoor Air Pollution and Lung Cancer in New Hampshire and Vermont. Toxicological and Environmental Chemistry. 94. PMID 24273369 DOI: 10.1080/02772248.2012.659930  0.656
2012 Bush WS, Moore JH. Chapter 11: Genome-wide association studies. Plos Computational Biology. 8: e1002822. PMID 23300413 DOI: 10.1371/Journal.Pcbi.1002822  0.612
2012 Andrew AS, Hu T, Gu J, Gui J, Ye Y, Marsit CJ, Kelsey KT, Schned AR, Tanyos SA, Pendleton EM, Mason RA, Morlock EV, Zens MS, Li Z, Moore JH, et al. HSD3B and gene-gene interactions in a pathway-based analysis of genetic susceptibility to bladder cancer. Plos One. 7: e51301. PMID 23284679 DOI: 10.1371/Journal.Pone.0051301  0.349
2012 Fung E, Patsopoulos NA, Belknap SM, O'Rourke DJ, Robb JF, Anderson JL, Shworak NW, Moore JH. Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin. Seminars in Thrombosis and Hemostasis. 38: 893-904. PMID 23041981 DOI: 10.1055/S-0032-1328891  0.327
2012 Urbanowicz RJ, Kiralis J, Sinnott-Armstrong NA, Heberling T, Fisher JM, Moore JH. GAMETES: a fast, direct algorithm for generating pure, strict, epistatic models with random architectures. Biodata Mining. 5: 16. PMID 23025260 DOI: 10.1186/1756-0381-5-16  0.685
2012 Urbanowicz RJ, Kiralis J, Fisher JM, Moore JH. Predicting the difficulty of pure, strict, epistatic models: metrics for simulated model selection. Biodata Mining. 5: 15. PMID 23014095 DOI: 10.1186/1756-0381-5-15  0.677
2012 Cowper-Sal lari R, Zhang X, Wright JB, Bailey SD, Cole MD, Eeckhoute J, Moore JH, Lupien M. Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nature Genetics. 44: 1191-8. PMID 23001124 DOI: 10.1038/Ng.2416  0.319
2012 Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, ... ... Moore JH, et al. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 120: 4873-81. PMID 22990020 DOI: 10.1182/Blood-2012-06-436188  0.322
2012 Urbach D, Lupien M, Karagas MR, Moore JH. Cancer heterogeneity: origins and implications for genetic association studies. Trends in Genetics : Tig. 28: 538-43. PMID 22858414 DOI: 10.1016/J.Tig.2012.07.001  0.373
2012 Kim NC, Andrews PC, Asselbergs FW, Frost HR, Williams SM, Harris BT, Read C, Askland KD, Moore JH. Gene ontology analysis of pairwise genetic associations in two genome-wide studies of sporadic ALS. Biodata Mining. 5: 9. PMID 22839596 DOI: 10.1186/1756-0381-5-9  0.738
2012 Zhang X, Cowper-Sal lari R, Bailey SD, Moore JH, Lupien M. Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus. Genome Research. 22: 1437-46. PMID 22665440 DOI: 10.1101/Gr.135665.111  0.345
2012 Lavender NA, Rogers EN, Yeyeodu S, Rudd J, Hu T, Zhang J, Brock GN, Kimbro KS, Moore JH, Hein DW, Kidd LC. Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer. Bmc Medical Genomics. 5: 11. PMID 22546513 DOI: 10.1186/1755-8794-5-11  0.335
2012 Ramanan VK, Shen L, Moore JH, Saykin AJ. Pathway analysis of genomic data: concepts, methods, and prospects for future development. Trends in Genetics : Tig. 28: 323-32. PMID 22480918 DOI: 10.1016/J.Tig.2012.03.004  0.361
2012 McAllister TW, Tyler AL, Flashman LA, Rhodes CH, McDonald BC, Saykin AJ, Tosteson TD, Tsongalis GJ, Moore JH. Polymorphisms in the brain-derived neurotrophic factor gene influence memory and processing speed one month after brain injury. Journal of Neurotrauma. 29: 1111-8. PMID 22188054 DOI: 10.1089/Neu.2011.1930  0.662
2012 Pechenick DA, Payne JL, Moore JH. The influence of assortativity on the robustness of signal-integration logic in gene regulatory networks. Journal of Theoretical Biology. 296: 21-32. PMID 22155134 DOI: 10.1016/J.Jtbi.2011.11.029  0.796
2012 Mechanic LE, Chen HS, Amos CI, Chatterjee N, Cox NJ, Divi RL, Fan R, Harris EL, Jacobs K, Kraft P, Leal SM, McAllister K, Moore JH, Paltoo DN, Province MA, et al. Next generation analytic tools for large scale genetic epidemiology studies of complex diseases. Genetic Epidemiology. 36: 22-35. PMID 22147673 DOI: 10.1002/Gepi.20652  0.672
2012 Fan R, Zhong M, Wang S, Zhang Y, Andrew A, Karagas M, Chen H, Amos CI, Xiong M, Moore JH. Entropy-based information gain approaches to detect and to characterize gene-gene and gene-environment interactions/correlations of complex diseases. Genetic Epidemiology. 35: 706-21. PMID 22009792 DOI: 10.1002/Gepi.20621  0.413
2012 Karagas MR, Andrew AS, Nelson HH, Li Z, Punshon T, Schned A, Marsit CJ, Morris JS, Moore JH, Tyler AL, Gilbert-Diamond D, Guerinot ML, Kelsey KT. SLC39A2 and FSIP1 polymorphisms as potential modifiers of arsenic-related bladder cancer. Human Genetics. 131: 453-61. PMID 21947419 DOI: 10.1007/S00439-011-1090-X  0.763
2012 Askland K, Read C, O'Connell C, Moore JH. Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing. Human Genetics. 131: 373-91. PMID 21866342 DOI: 10.1007/S00439-011-1082-X  0.343
2012 Hu T, Payne JL, Banzhaf W, Moore JH. Evolutionary dynamics on multiple scales: A quantitative analysis of the interplay between genotype, phenotype, and fitness in linear genetic programming Genetic Programming and Evolvable Machines. 13: 305-337. DOI: 10.1007/S10710-012-9159-4  0.318
2011 Darabos C, Di Cunto F, Tomassini M, Moore JH, Provero P, Giacobini M. Additive functions in boolean models of gene regulatory network modules Plos One. 6. PMID 22132067 DOI: 10.1371/Journal.Pone.0025110  0.799
2011 Hu T, Sinnott-Armstrong NA, Kiralis JW, Andrew AS, Karagas MR, Moore JH. Characterizing genetic interactions in human disease association studies using statistical epistasis networks. Bmc Bioinformatics. 12: 364. PMID 21910885 DOI: 10.1186/1471-2105-12-364  0.429
2011 Urbach D, Moore JH. Mining the diseasome. Biodata Mining. 4: 25. PMID 21906309 DOI: 10.1186/1756-0381-4-25  0.409
2011 Penrod NM, Cowper-Sal-lari R, Moore JH. Systems genetics for drug target discovery. Trends in Pharmacological Sciences. 32: 623-30. PMID 21862141 DOI: 10.1016/J.Tips.2011.07.002  0.808
2011 Himmelstein DS, Greene CS, Moore JH. Evolving hard problems: Generating human genetics datasets with a complex etiology. Biodata Mining. 4: 21. PMID 21736753 DOI: 10.1186/1756-0381-4-21  0.808
2011 Gilbert-Diamond D, Moore JH. Analysis of gene-gene interactions. Current Protocols in Human Genetics. Unit1.14. PMID 21735376 DOI: 10.1002/0471142905.Hg0114S70  0.643
2011 Urbach D, Moore JH. Mining beyond the exome. Biodata Mining. 4: 14. PMID 21668977 DOI: 10.1186/1756-0381-4-14  0.365
2011 Urbach D, Moore JH. Data mining and the evolution of biological complexity. Biodata Mining. 4: 7. PMID 21477342 DOI: 10.1186/1756-0381-4-7  0.365
2011 Urbach D, Moore JH. The spatial dimension in biological data mining. Biodata Mining. 4: 6. PMID 21477341 DOI: 10.1186/1756-0381-4-6  0.326
2011 Penrod NM, Poku KA, Vaughan DE, Vaughn DE, Asselbergs FW, Brown NJ, Moore JH, Williams SM. Epistatic interactions in genetic regulation of t-PA and PAI-1 levels in a Ghanaian population. Plos One. 6: e16639. PMID 21304999 DOI: 10.1371/Journal.Pone.0016639  0.789
2011 Cowper-Sal lari R, Cole MD, Karagas MR, Lupien M, Moore JH. Layers of epistasis: genome-wide regulatory networks and network approaches to genome-wide association studies. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 513-26. PMID 21197657 DOI: 10.1002/Wsbm.132  0.388
2011 Wishart HA, Roth RM, Saykin AJ, Rhodes CH, Tsongalis GJ, Pattin KA, Moore JH, McAllister TW. COMT Val158Met Genotype and Individual Differences in Executive Function in Healthy Adults. Journal of the International Neuropsychological Society : Jins. 17: 174-80. PMID 21144101 DOI: 10.1017/S1355617710001402  0.789
2011 Gui J, Andrew AS, Andrews P, Nelson HM, Kelsey KT, Karagas MR, Moore JH. A robust multifactor dimensionality reduction method for detecting gene-gene interactions with application to the genetic analysis of bladder cancer susceptibility. Annals of Human Genetics. 75: 20-8. PMID 21091664 DOI: 10.1111/J.1469-1809.2010.00624.X  0.424
2011 Gui J, Moore JH, Kelsey KT, Marsit CJ, Karagas MR, Andrew AS. A novel survival multifactor dimensionality reduction method for detecting gene-gene interactions with application to bladder cancer prognosis. Human Genetics. 129: 101-10. PMID 20981448 DOI: 10.1007/S00439-010-0905-5  0.4
2011 Darabos C, Tomassini M, Cunto FD, Provero P, Moore JH, Giacobini M. Toward robust network based complex systems: from evolutionary cellular automata to biological models Intelligenza Artificiale. 5: 37-47. DOI: 10.3233/Ia-2011-0003  0.792
2011 Penrod NM, Poku KA, Vaughn DE, Asselbergs FW, Brown NJ, Moore JH, Williams SM. Correction: Epistatic Interactions in Genetic Regulation of t-PA and PAI-1 Levels in a Ghanaian Population Plos One. 6. DOI: 10.1371/Annotation/2501Cac9-F313-406F-919B-314F12B43516  0.778
2010 Pattin KA, Moore JH. Genome-wide association studies for the identification of biomarkers in metabolic diseases. Expert Opinion On Medical Diagnostics. 4: 39-51. PMID 23496109 DOI: 10.1517/17530050903322245  0.787
2010 Moore JH. Detecting, characterizing, and interpreting nonlinear gene-gene interactions using multifactor dimensionality reduction. Advances in Genetics. 72: 101-16. PMID 21029850 DOI: 10.1016/B978-0-12-380862-2.00005-9  0.415
2010 Gui J, Andrew AS, Andrews P, Nelson HM, Kelsey KT, Karagas MR, Moore JH. A simple and computationally efficient sampling approach to covariate adjustment for multifactor dimensionality reduction analysis of epistasis. Human Heredity. 70: 219-25. PMID 20924193 DOI: 10.1159/000319175  0.395
2010 Bentley JP, Asselbergs FW, Coffey CS, Hebert PR, Moore JH, Hillege HL, van Gilst WH. Cardiovascular risk associated with interactions among polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems. Plos One. 5: e12757. PMID 20856803 DOI: 10.1371/Journal.Pone.0012757  0.338
2010 Eichler EE, Flint J, Gibson G, Kong A, Leal SM, Moore JH, Nadeau JH. Missing heritability and strategies for finding the underlying causes of complex disease. Nature Reviews. Genetics. 11: 446-50. PMID 20479774 DOI: 10.1038/Nrg2809  0.383
2010 Sloan CD, Shen L, West JD, Wishart HA, Flashman LA, Rabin LA, Santulli RB, Guerin SJ, Rhodes CH, Tsongalis GJ, McAllister TW, Ahles TA, Lee SL, Moore JH, Saykin AJ. Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1060-9. PMID 20468060 DOI: 10.1002/Ajmg.B.31078  0.691
2010 Saykin AJ, Shen L, Foroud TM, Potkin SG, Swaminathan S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craig DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, et al. Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 265-73. PMID 20451875 DOI: 10.1016/J.Jalz.2010.03.013  0.354
2010 Shen L, Kim S, Risacher SL, Nho K, Swaminathan S, West JD, Foroud T, Pankratz N, Moore JH, Sloan CD, Huentelman MJ, Craig DW, Dechairo BM, Potkin SG, Jack CR, et al. Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort. Neuroimage. 53: 1051-63. PMID 20100581 DOI: 10.1016/J.Neuroimage.2010.01.042  0.721
2010 Greene CS, Sinnott-Armstrong NA, Himmelstein DS, Park PJ, Moore JH, Harris BT. Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS. Bioinformatics (Oxford, England). 26: 694-5. PMID 20081222 DOI: 10.1093/Bioinformatics/Btq009  0.806
2010 Moore JH, Asselbergs FW, Williams SM. Bioinformatics challenges for genome-wide association studies. Bioinformatics (Oxford, England). 26: 445-55. PMID 20053841 DOI: 10.1093/Bioinformatics/Btp713  0.411
2010 Greene CS, Himmelstein DS, Nelson HH, Kelsey KT, Williams SM, Andrew AS, Karagas MR, Moore JH. Enabling personal genomics with an explicit test of epistasis. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 327-36. PMID 19908385  0.822
2010 Lavender NA, Komolafe OO, Benford M, Brock G, Moore JH, Vancleave TT, States JC, Kittles RA, Kidd LC. No association between variant DNA repair genes and prostate cancer risk among men of African descent. The Prostate. 70: 113-9. PMID 19760636 DOI: 10.1002/Pros.21048  0.323
2009 Greene CS, White BC, Moore JH. Sensible Initialization Using Expert Knowledge for Genome-Wide Analysis of Epistasis Using Genetic Programming. Genetic and Evolutionary Computation Conference : [Proceedings] / Sponsored by Acm Sigevo. Genetic and Evolutionary Computation Conference. 2009: 1289-1296. PMID 21197156 DOI: 10.1109/CEC.2009.4983093  0.686
2009 Pattin KA, Moore JH. Role for protein-protein interaction databases in human genetics. Expert Review of Proteomics. 6: 647-59. PMID 19929610 DOI: 10.1586/Epr.09.86  0.794
2009 Dervieux T, Wessels JA, van der Straaten T, Penrod N, Moore JH, Guchelaar HJ, Kremer JM. Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis. Pharmacogenetics and Genomics. 19: 935-44. PMID 19858780 DOI: 10.1097/Fpc.0B013E32833315D1  0.79
2009 Greene CS, Penrod NM, Kiralis J, Moore JH. Spatially uniform relieff (SURF) for computationally-efficient filtering of gene-gene interactions. Biodata Mining. 2: 5. PMID 19772641 DOI: 10.1186/1756-0381-2-5  0.811
2009 Sloan CD, Andrew AD, Duell EJ, Williams SM, Karagas MR, Moore JH. Genetic population structure analysis in New Hampshire reveals Eastern European ancestry. Plos One. 4: e6928. PMID 19738909 DOI: 10.1371/Journal.Pone.0006928  0.709
2009 Moore JH, Williams SM. Epistasis and its implications for personal genetics. American Journal of Human Genetics. 85: 309-20. PMID 19733727 DOI: 10.1016/J.Ajhg.2009.08.006  0.402
2009 Norris PR, Canter JA, Jenkins JM, Moore JH, Williams AE, Morris JA. Personalized medicine: genetic variation and loss of physiologic complexity are associated with mortality in 644 trauma patients. Annals of Surgery. 250: 524-30. PMID 19730237 DOI: 10.1097/Sla.0B013E3181B8Fb1F  0.312
2009 Sinnott-Armstrong NA, Greene CS, Cancare F, Moore JH. Accelerating epistasis analysis in human genetics with consumer graphics hardware. Bmc Research Notes. 2: 149. PMID 19630950 DOI: 10.1186/1756-0500-2-149  0.701
2009 Greene CS, Penrod NM, Williams SM, Moore JH. Failure to replicate a genetic association may provide important clues about genetic architecture. Plos One. 4: e5639. PMID 19503614 DOI: 10.1371/Journal.Pone.0005639  0.803
2009 Morris JA, Francois C, Olson PK, Cotton BA, Summar M, Jenkins JM, Norris PR, Moore JH, Williams AE, McNew BS, Canter JA. Genetic variation in complement component 2 of the classical complement pathway is associated with increased mortality and infection: a study of 627 patients with trauma. The Journal of Trauma. 66: 1265-70; discussion . PMID 19430225 DOI: 10.1097/Ta.0B013E31819Ea61A  0.306
2009 Arehart E, Gleim S, White BC, Hwa J, Moore JH. Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms Biodata Mining. 2: 2-2. PMID 19331672 DOI: 10.1186/1756-0381-2-2  0.35
2009 Andrew AS, Gui J, Sanderson AC, Mason RA, Morlock EV, Schned AR, Kelsey KT, Marsit CJ, Moore JH, Karagas MR. Bladder cancer SNP panel predicts susceptibility and survival. Human Genetics. 125: 527-39. PMID 19252927 DOI: 10.1007/S00439-009-0645-6  0.336
2009 Tyler AL, Asselbergs FW, Williams SM, Moore JH. Shadows of complexity: what biological networks reveal about epistasis and pleiotropy. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 31: 220-7. PMID 19204994 DOI: 10.1002/Bies.200800022  0.717
2009 Askland K, Read C, Moore J. Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission. Human Genetics. 125: 63-79. PMID 19052778 DOI: 10.1007/S00439-008-0600-Y  0.356
2009 Sloan CD, Duell EJ, Shi X, Irwin R, Andrew AS, Williams SM, Moore JH. Ecogeographic genetic epidemiology. Genetic Epidemiology. 33: 281-9. PMID 19025788 DOI: 10.1002/Gepi.20386  0.721
2009 Reif DM, Motsinger-Reif AA, McKinney BA, Rock MT, Crowe JE, Moore JH. Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination. Genes and Immunity. 10: 112-9. PMID 18923431 DOI: 10.1038/Gene.2008.80  0.715
2009 Pattin KA, White BC, Barney N, Gui J, Nelson HH, Kelsey KT, Andrew AS, Karagas MR, Moore JH. A computationally efficient hypothesis testing method for epistasis analysis using multifactor dimensionality reduction. Genetic Epidemiology. 33: 87-94. PMID 18671250 DOI: 10.1002/Gepi.20360  0.795
2009 Moore JH, Clegg J, Marchiori E, Ritchie M, Smith S. Editorial: artificial evolution methods in the biological and biomedical sciences Journal of Artificial Evolution and Applications. 2009: 1-1. DOI: 10.1155/2009/956380  0.569
2009 Urbanowicz RJ, Moore JH. Learning Classifier Systems: A Complete Introduction, Review, and Roadmap Journal of Artificial Evolution and Applications. 2009: 1-25. DOI: 10.1155/2009/736398  0.665
2008 Sloan CD, Sayarath V, Moore JH. Systems genetics of alcoholism Alcohol Research and Health. 31: 14-25. PMID 23584748  0.703
2008 Urbanowicz RJ, White BC, Moore JH. Mask Functions for the Symbolic Modeling of Epistasis Using Genetic Programming. Genetic and Evolutionary Computation Conference : [Proceedings] / Sponsored by Acm Sigevo. Genetic and Evolutionary Computation Conference. 2008: 339-346. PMID 23019565  0.685
2008 Wilke RA, Mareedu RK, Moore JH. The Pathway Less Traveled: Moving from Candidate Genes to Candidate Pathways in the Analysis of Genome-Wide Data from Large Scale Pharmacogenetic Association Studies. Current Pharmacogenomics and Personalized Medicine. 6: 150-159. PMID 19421424 DOI: 10.2174/1875692110806030150  0.368
2008 Asselbergs FW, Pattin K, Snieder H, Hillege HL, van Gilst WH, Moore JH. Genetic architecture of tissue-type plasminogen activator and plasminogen activator inhibitor-1. Seminars in Thrombosis and Hemostasis. 34: 562-8. PMID 19085655 DOI: 10.1055/S-0028-1103367  0.796
2008 Aguilar-Ruiz JS, Moore JH, Ritchie MD. Filling the gap between biology and computer science. Biodata Mining. 1: 1. PMID 18822148 DOI: 10.1186/1756-0381-1-1  0.591
2008 Lee JH, Moore JH, Park SW, Jang AS, Uh ST, Kim YH, Park CS, Park BL, Shin HD. Genetic interactions model among Eotaxin gene polymorphisms in asthma. Journal of Human Genetics. 53: 867-875. PMID 18712274 DOI: 10.1007/S10038-008-0314-Y  0.341
2008 McAllister TW, Flashman LA, Harker Rhodes C, Tyler AL, Moore JH, Saykin AJ, McDonald BC, Tosteson TD, Tsongalis GJ. Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: a replication and extension study. Brain Injury. 22: 705-14. PMID 18698520 DOI: 10.1080/02699050802263019  0.676
2008 Beretta L, Cappiello F, Moore JH, Barili M, Greene CS, Scorza R. Ability of epistatic interactions of cytokine single-nucleotide polymorphisms to predict susceptibility to disease subsets in systemic sclerosis patients. Arthritis and Rheumatism. 59: 974-83. PMID 18576303 DOI: 10.1002/Art.23836  0.701
2008 Duell EJ, Bracci PM, Moore JH, Burk RD, Kelsey KT, Holly EA. Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 1470-9. PMID 18559563 DOI: 10.1158/1055-9965.Epi-07-2797  0.322
2008 Pattin KA, Moore JH. Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases. Human Genetics. 124: 19-29. PMID 18551320 DOI: 10.1007/S00439-008-0522-8  0.82
2008 Reif DM, McKinney BA, Motsinger AA, Chanock SJ, Edwards KM, Rock MT, Moore JH, Crowe JE. Genetic basis for adverse events after smallpox vaccination. The Journal of Infectious Diseases. 198: 16-22. PMID 18454680 DOI: 10.1086/588670  0.6
2008 Beretta L, Cappiello F, Moore JH, Scorza R. Interleukin-1 gene complex single nucleotide polymorphisms in systemic sclerosis: a further step ahead. Human Immunology. 69: 187-192. PMID 18396211 DOI: 10.1016/J.Humimm.2007.12.006  0.341
2008 Thornton-Wells TA, Moore JH, Martin ER, Pericak-Vance MA, Haines JL. Confronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasis. Genetic Epidemiology. 32: 187-203. PMID 18076107 DOI: 10.1002/Gepi.20294  0.393
2008 Greene CS, Moore JH. Solving complex problems in human genetics using GP Acm Sigevolution. 3: 2-8. DOI: 10.1145/1527063.1527064  0.724
2007 Ritchie MD, Motsinger AA, Bush WS, Coffey CS, Moore JH. Genetic Programming Neural Networks: A Powerful Bioinformatics Tool for Human Genetics. Applied Soft Computing. 7: 471-479. PMID 20948988 DOI: 10.1016/J.Asoc.2006.01.013  0.746
2007 Reif DM, Israel MA, Moore JH. Exploratory Visual Analysis of statistical results from microarray experiments comparing high and low grade glioma. Cancer Informatics. 5: 19-24. PMID 19390666 DOI: 10.4137/Cin.S0  0.617
2007 Williams SM, Canter JA, Crawford DC, Moore JH, Ritchie MD, Haines JL. Problems with genome-wide association studies. Science (New York, N.Y.). 316: 1840-2. PMID 17605173  0.543
2007 Asselbergs FW, Williams SM, Hebert PR, Coffey CS, Hillege HL, Snieder H, Navis G, Vaughan DE, van Gilst WH, Moore JH. The effects of polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems on plasma t-PA and PAI-1 levels are dependent on environmental context. Human Genetics. 122: 275-81. PMID 17593394 DOI: 10.1007/S00439-007-0400-9  0.339
2007 McKinney BA, Reif DM, White BC, Crowe JE, Moore JH. Evaporative cooling feature selection for genotypic data involving interactions. Bioinformatics (Oxford, England). 23: 2113-20. PMID 17586549 DOI: 10.1093/Bioinformatics/Btm317  0.631
2007 Julià A, Moore J, Miquel L, Alegre C, Barceló P, Ritchie M, Marsal S. Identification of a two-loci epistatic interaction associated with susceptibility to rheumatoid arthritis through reverse engineering and multifactor dimensionality reduction. Genomics. 90: 6-13. PMID 17482423 DOI: 10.1016/J.Ygeno.2007.03.011  0.596
2007 Garcia-Barcelo M, King SK, Miao X, So Mt, Holden WT, Moore JH, Sutcliffe JR, Hutson JM, Tam PKH. Application of HapMap data to the evaluation of 8 candidate genes for pediatric slow transit constipation Journal of Pediatric Surgery. 42: 666-671. PMID 17448763 DOI: 10.1016/J.Jpedsurg.2006.12.014  0.314
2007 Velez DR, White BC, Motsinger AA, Bush WS, Ritchie MD, Williams SM, Moore JH. A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction. Genetic Epidemiology. 31: 306-15. PMID 17323372 DOI: 10.1002/Gepi.20211  0.709
2007 Nordgard SH, Ritchie MD, Jensrud SD, Motsinger AA, Alnaes GI, Lemmon G, Berg M, Geisler S, Moore JH, Lønning PE, Børresen-Dale AL, Kristensen VN. ABCB1 and GST polymorphisms associated with TP53 status in breast cancer. Pharmacogenetics and Genomics. 17: 127-36. PMID 17301692 DOI: 10.1097/Fpc.0B013E328011Abaa  0.636
2007 Garcia-Barceló MM, Miao X, Lui VC, So MT, Ngan ES, Leon TY, Lau DK, Liu TT, Lao X, Guo W, Holden WT, Moore J, Tam PK. Correlation between genetic variations in Hox clusters and Hirschsprung's disease. Annals of Human Genetics. 71: 526-36. PMID 17274802 DOI: 10.1111/J.1469-1809.2007.00347.X  0.38
2007 Coutinho AM, Sousa I, Martins M, Correia C, Morgadinho T, Bento C, Marques C, Ataíde A, Miguel TS, Moore JH, Oliveira G, Vicente AM. Evidence for epistasis between SLC6A4 and ITGB3 in autism etiology and in the determination of platelet serotonin levels. Human Genetics. 121: 243-256. PMID 17203304 DOI: 10.1007/S00439-006-0301-3  0.36
2007 Tsai CT, Hwang JJ, Ritchie MD, Moore JH, Chiang FT, Lai LP, Hsu KL, Tseng CD, Lin JL, Tseng YZ. Renin-angiotensin system gene polymorphisms and coronary artery disease in a large angiographic cohort: detection of high order gene-gene interaction. Atherosclerosis. 195: 172-80. PMID 17118372 DOI: 10.1016/J.Atherosclerosis.2006.09.014  0.626
2007 Eppstein MJ, Payne JL, White BC, Moore JH. Genomic mining for complex disease traits with "random chemistry" Genetic Programming and Evolvable Machines. 8: 395-411. DOI: 10.1007/S10710-007-9039-5  0.423
2006 McKinney BA, Reif DM, Rock MT, Edwards KM, Kingsmore SF, Moore JH, Crowe JE. Cytokine expression patterns associated with systemic adverse events following smallpox immunization. The Journal of Infectious Diseases. 194: 444-53. PMID 16845627 DOI: 10.1086/505503  0.547
2006 McKinney BA, Reif DM, Ritchie MD, Moore JH. Machine learning for detecting gene-gene interactions: a review. Applied Bioinformatics. 5: 77-88. PMID 16722772 DOI: 10.2165/00822942-200605020-00002  0.756
2006 Asselbergs FW, Moore JH, Berg MPvd, Rimm EB, Boer RAd, Dullaart RP, Navis G, Gilst WHv. A role for CETP TaqIB polymorphism in determining susceptibility to atrial fibrillation: a nested case control study Bmc Medical Genetics. 7: 39-39. PMID 16623947 DOI: 10.1186/1471-2350-7-39  0.343
2006 Thornton-Wells TA, Moore JH, Haines JL. Dissecting trait heterogeneity: a comparison of three clustering methods applied to genotypic data. Bmc Bioinformatics. 7: 204. PMID 16611359 DOI: 10.1186/1471-2105-7-204  0.38
2006 Reif DM, Moore JH. Visual analysis of statistical results from microarray studies of human breast cancer. Oncology Reports. 15: 1043-7. PMID 16525698  0.56
2006 Moore JH, Gilbert JC, Tsai CT, Chiang FT, Holden T, Barney N, White BC. A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility. Journal of Theoretical Biology. 241: 252-61. PMID 16457852 DOI: 10.1016/J.Jtbi.2005.11.036  0.402
2006 Sanada H, Yatabe J, Midorikawa S, Hashimoto S, Watanabe T, Moore JH, Ritchie MD, Williams SM, Pezzullo JC, Sasaki M, Eisner GM, Jose PA, Felder RA. Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension. Clinical Chemistry. 52: 352-60. PMID 16439609 DOI: 10.1373/Clinchem.2005.059139  0.579
2006 Martin ER, Ritchie MD, Hahn L, Kang S, Moore JH. A novel method to identify gene-gene effects in nuclear families: The MDR-PDT Genetic Epidemiology. 30: 111-123. PMID 16374833 DOI: 10.1002/Gepi.20128  0.657
2006 Andrew AS, Nelson HH, Kelsey KT, Moore JH, Meng AC, Casella DP, Tosteson TD, Schned AR, Karagas MR. Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility. Carcinogenesis. 27: 1030-7. PMID 16311243 DOI: 10.1093/Carcin/Bgi284  0.336
2005 Xu J, Lowey J, Wiklund F, Sun J, Lindmark F, Hsu FC, Dimitrov L, Chang B, Turner AR, Liu W, Adami HO, Suh E, Moore JH, Zheng SL, Isaacs WB, et al. The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 2563-8. PMID 16284379 DOI: 10.1158/1055-9965.Epi-05-0356  0.33
2005 Wilke RA, Reif DM, Moore JH. Combinatorial pharmacogenetics. Nature Reviews. Drug Discovery. 4: 911-8. PMID 16264434 DOI: 10.1038/nrd1874  0.571
2005 Moore JH, Williams SM. Traversing the conceptual divide between biological and statistical epistasis: Systems biology and a more modern synthesis Bioessays. 27: 637-646. PMID 15892116 DOI: 10.1002/Bies.20236  0.409
2005 Reif DM, Dudek SM, Shaffer CM, Wang J, Moore JH. Exploratory visual analysis of pharmacogenomic results. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 296-307. PMID 15759635  0.536
2005 Moore JH, Boczko EM, Summar ML. Connecting the dots between genes, biochemistry, and disease susceptibility: systems biology modeling in human genetics. Molecular Genetics and Metabolism. 84: 104-11. PMID 15670716 DOI: 10.1016/J.Ymgme.2004.10.006  0.371
2005 Moore JH. A global view of epistasis. Nature Genetics. 37: 13-14. PMID 15624016 DOI: 10.1038/Ng0105-13  0.351
2005 Skaar DA, Shao Y, Haines JL, Stenger JE, Jaworski J, Martin ER, DeLong GR, Moore JH, McCauley JL, Sutcliffe JS, Ashley-Koch AE, Cuccaro ML, Folstein SE, Gilbert JR, Pericak-Vance MA. Analysis of the RELN gene as a genetic risk factor for autism. Molecular Psychiatry. 10: 563-71. PMID 15558079 DOI: 10.1038/Sj.Mp.4001614  0.364
2004 Moore JH, Hahn LW, Ritchie MD, Thornton TA, White BC. Routine Discovery of Complex Genetic Models using Genetic Algorithms. Applied Soft Computing. 4: 79-86. PMID 20948983 DOI: 10.1016/J.Asoc.2003.08.003  0.673
2004 Reif DM, White BC, Moore JH. Integrated analysis of genetic, genomic and proteomic data. Expert Review of Proteomics. 1: 67-75. PMID 15966800 DOI: 10.1586/14789450.1.1.67  0.625
2004 Moore JH. Computational analysis of gene-gene interactions using multifactor dimensionality reduction. Expert Review of Molecular Diagnostics. 4: 795-803. PMID 15525222 DOI: 10.1586/14737159.4.6.795  0.405
2004 Thornton-Wells TA, Moore JH, Haines JL. Genetics, statistics and human disease: analytical retooling for complexity. Trends in Genetics : Tig. 20: 640-7. PMID 15522460 DOI: 10.1016/J.Tig.2004.09.007  0.385
2004 Aune TM, Parker JS, Maas K, Liu Z, Olsen NJ, Moore JH. Co-localization of differentially expressed genes and shared susceptibility loci in human autoimmunity. Genetic Epidemiology. 27: 162-72. PMID 15305332 DOI: 10.1002/Gepi.20013  0.376
2004 Olsen NJ, Moore JH, Aune TM. Gene expression signatures for autoimmune disease in peripheral blood mononuclear cells. Arthritis Research & Therapy. 6: 120-8. PMID 15142262 DOI: 10.1186/Ar1190  0.332
2004 Williams SM, Ritchie MD, Phillips JA, Dawson E, Prince M, Dzhura E, Willis A, Semenya A, Summar M, White BC, Addy JH, Kpodonu J, Wong LJ, Felder RA, Jose PA, ... Moore JH, et al. Multilocus analysis of hypertension: a hierarchical approach. Human Heredity. 57: 28-38. PMID 15133310 DOI: 10.1159/000077387  0.637
2004 Coffey CS, Hebert PR, Ritchie MD, Krumholz HM, Gaziano JM, Ridker PM, Brown NJ, Vaughan DE, Moore JH. An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation. Bmc Bioinformatics. 5: 49. PMID 15119966 DOI: 10.1186/1471-2105-5-49  0.617
2004 Moore JH, Ritchie MD. STUDENTJAMA. The challenges of whole-genome approaches to common diseases. Jama. 291: 1642-3. PMID 15069055 DOI: 10.1001/Jama.291.13.1642  0.688
2004 Aune TM, Maas K, Parker J, Moore JH, Olsen NJ. Profiles of gene expression in human autoimmune disease. Cell Biochemistry and Biophysics. 40: 81-96. PMID 15054216 DOI: 10.1385/Cbb:40:2:081  0.34
2004 Tsai CT, Lai LP, Lin JL, Chiang FT, Hwang JJ, Ritchie MD, Moore JH, Hsu KL, Tseng CD, Liau CS, Tseng YZ. Renin-angiotensin system gene polymorphisms and atrial fibrillation. Circulation. 109: 1640-6. PMID 15023884 DOI: 10.1161/01.Cir.0000124487.36586.26  0.586
2004 Williams SM, Haines JL, Moore JH. The use of animal models in the study of complex disease: all else is never equal or why do so many human studies fail to replicate animal findings? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 26: 170-9. PMID 14745835 DOI: 10.1002/Bies.10401  0.389
2004 Cho YM, Ritchie MD, Moore JH, Park JY, Lee KU, Shin HD, Lee HK, Park KS. Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus Diabetologia. 47: 549-554. PMID 14730379 DOI: 10.1007/S00125-003-1321-3  0.612
2004 Moore JH, Hahn LW. An Improved Grammatical Evolution Strategy for Hierarchical Petri Net Modeling of Complex Genetic Systems Lecture Notes in Computer Science. 63-72. DOI: 10.1007/978-3-540-24653-4_7  0.354
2003 Moore JH, Thornton TA, Ritchie MD. Basic statistics. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Appendix 3M. PMID 18428338 DOI: 10.1002/0471142905.Hga03Ms37  0.595
2003 Moore JH, Hahn LW. Petri net modeling of high-order genetic systems using grammatical evolution. Biosystems. 72: 177-186. PMID 14642666 DOI: 10.1016/S0303-2647(03)00142-4  0.353
2003 Moore JH. The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases Human Heredity. 56: 73-82. PMID 14614241 DOI: 10.1159/000073735  0.41
2003 Aune TM, Maas K, Moore JH, Olsen NJ. Gene expression profiles in human autoimmune disease. Current Pharmaceutical Design. 9: 1905-17. PMID 12871194 DOI: 10.2174/1381612033454360  0.3
2003 Ritchie MD, White BC, Parker JS, Hahn LW, Moore JH. Optimization of neural network architecture using genetic programming improves detection and modeling of gene-gene interactions in studies of human diseases. Bmc Bioinformatics. 4: 28. PMID 12846935 DOI: 10.1186/1471-2105-4-28  0.639
2003 Hahn LW, Ritchie MD, Moore JH. Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics (Oxford, England). 19: 376-82. PMID 12584123 DOI: 10.1093/Bioinformatics/Btf869  0.663
2003 Ritchie MD, Hahn LW, Moore JH. Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity. Genetic Epidemiology. 24: 150-7. PMID 12548676 DOI: 10.1002/Gepi.10218  0.667
2003 Moore JH, Hahn LW. Evaluation of a discrete dynamic systems approach for modeling the hierarchical relationship between genes, biochemistry, and disease susceptibility Discrete and Continuous Dynamical Systems-Series B. 4: 275-287. DOI: 10.3934/Dcdsb.2004.4.275  0.393
2003 Moore JH. Cross validation consistency for the assessment of genetic programming results in microarray studies Lecture Notes in Computer Science. 99-106. DOI: 10.1007/3-540-36605-9_10  0.342
2002 Moore JH, Hahn LW, Ritchie MD, Thornton TA, White BC. Application of Genetic Algorithms to the Discovery of Complex Models for Simulation Studies in Human Genetics. Proceedings of the Genetic and Evolutionary Computation Conference / Gecco. Genetic and Evolutionary Computation Conference. 2002: 1150-1155. PMID 23413413  0.614
2002 Moore JH, Parker JS, Olsen NJ, Aune TM. Symbolic discriminant analysis of microarray data in autoimmune disease. Genetic Epidemiology. 23: 57-69. PMID 12112248 DOI: 10.1002/Gepi.1117  0.358
2002 Moore JH, Williams SM. New strategies for identifying gene-gene interactions in hypertension Annals of Medicine. 34: 88-95. PMID 12108579 DOI: 10.1080/07853890252953473  0.395
2001 Moore JH. Improved power of sib-pair linkage analysis using measures of complex trait dynamics. Human Heredity. 52: 113-115. PMID 11474213 DOI: 10.1159/000053363  0.34
2001 Ritchie MD, Hahn LW, Roodi N, Bailey LR, Dupont WD, Parl FF, Moore JH. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer American Journal of Human Genetics. 69: 138-147. PMID 11404819 DOI: 10.1086/321276  0.658
2000 Schwartz GL, Turner ST, Moore JH, Sing CF. Effect of time of day on intraindividual variability in ambulatory blood pressure. American Journal of Hypertension. 13: 1203-9. PMID 11078181 DOI: 10.1016/S0895-7061(00)01198-5  0.535
2000 Schwartz GL, Turner ST, Moore JH, Sing CF. Predictors of interindividual variation in ambulatory blood pressure and their time or activity dependence. American Journal of Hypertension. 13: 52-60. PMID 10678271 DOI: 10.1016/S0895-7061(99)00127-2  0.563
1997 Moore JH, Reilly SL, Ferrell RE, Sing CF. The role of the apolipoprotein E polymorphism in the prediction of coronary artery disease age of onset. Clinical Genetics. 51: 22-5. PMID 9084929 DOI: 10.1111/J.1399-0004.1997.Tb02408.X  0.554
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