| Year |
Citation |
Score |
| 2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Jensen SE, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.34 |
|
| 2013 |
Kwong T, Tahlan K, Anders CL, Jensen SE. Carboxyethylarginine synthase genes show complex cross-regulation in Streptomyces clavuligerus. Applied and Environmental Microbiology. 79: 240-9. PMID 23104404 DOI: 10.1128/Aem.02600-12 |
0.612 |
|
| 2012 |
Jensen SE. Biosynthesis of clavam metabolites. Journal of Industrial Microbiology & Biotechnology. 39: 1407-19. PMID 22948564 DOI: 10.1007/s10295-012-1191-0 |
0.321 |
|
| 2012 |
Kwong T, Zelyas NJ, Cai H, Tahlan K, Wong A, Jensen SE. 5S clavam biosynthesis is controlled by an atypical two-component regulatory system in Streptomyces clavuligerus. Antimicrobial Agents and Chemotherapy. 56: 4845-55. PMID 22751548 DOI: 10.1128/Aac.01090-12 |
0.644 |
|
| 2012 |
Goomeshi Nobary S, Jensen SE. A comparison of the clavam biosynthetic gene clusters in Streptomyces antibioticus Tü1718 and Streptomyces clavuligerus. Canadian Journal of Microbiology. 58: 413-25. PMID 22435762 DOI: 10.1139/w2012-012 |
0.494 |
|
| 2011 |
Shaheen M, Li J, Ross AC, Vederas JC, Jensen SE. Paenibacillus polymyxa PKB1 produces variants of polymyxin B-type antibiotics. Chemistry & Biology. 18: 1640-8. PMID 22195566 DOI: 10.1016/J.Chembiol.2011.09.017 |
0.41 |
|
| 2010 |
Song JY, Jensen SE, Lee KJ. Clavulanic acid biosynthesis and genetic manipulation for its overproduction. Applied Microbiology and Biotechnology. 88: 659-69. PMID 20711575 DOI: 10.1007/s00253-010-2801-2 |
0.421 |
|
| 2009 |
Zelyas N, Tahlan K, Jensen SE. Use of the native flp gene to generate in-frame unmarked mutations in Streptomyces spp. Gene. 443: 48-54. PMID 19446014 DOI: 10.1016/j.gene.2009.03.022 |
0.392 |
|
| 2009 |
Song JY, Kim ES, Kim DW, Jensen SE, Lee KJ. A gene located downstream of the clavulanic acid gene cluster in Streptomyces clavuligerus ATCC 27064 encodes a putative response regulator that affects clavulanic acid production. Journal of Industrial Microbiology & Biotechnology. 36: 301-11. PMID 19011915 DOI: 10.1007/s10295-008-0499-2 |
0.504 |
|
| 2008 |
Zelyas NJ, Cai H, Kwong T, Jensen SE. Alanylclavam biosynthetic genes are clustered together with one group of clavulanic acid biosynthetic genes in Streptomyces clavuligerus. Journal of Bacteriology. 190: 7957-65. PMID 18931110 DOI: 10.1128/Jb.00698-08 |
0.692 |
|
| 2008 |
Song JY, Kim ES, Kim DW, Jensen SE, Lee KJ. Functional effects of increased copy number of the gene encoding proclavaminate amidino hydrolase on clavulanic acid production in Streptomyces clavuligerus ATCC 27064. Journal of Microbiology and Biotechnology. 18: 417-26. PMID 18388457 |
0.458 |
|
| 2008 |
Li J, Jensen SE. Nonribosomal biosynthesis of fusaricidins by Paenibacillus polymyxa PKB1 involves direct activation of a D-amino acid. Chemistry & Biology. 15: 118-27. PMID 18291316 DOI: 10.1016/j.chembiol.2007.12.014 |
0.401 |
|
| 2007 |
Alexander DC, Anders CL, Lee L, Jensen SE. pcd mutants of Streptomyces clavuligerus still produce cephamycin C. Journal of Bacteriology. 189: 5867-74. PMID 17573474 DOI: 10.1128/JB.00712-07 |
0.47 |
|
| 2007 |
Li J, Beatty PK, Shah S, Jensen SE. Use of PCR-targeted mutagenesis to disrupt production of fusaricidin-type antifungal antibiotics in Paenibacillus polymyxa. Applied and Environmental Microbiology. 73: 3480-9. PMID 17400768 DOI: 10.1128/AEM.02662-06 |
0.346 |
|
| 2007 |
Tahlan K, Anders C, Wong A, Mosher RH, Beatty PH, Brumlik MJ, Griffin A, Hughes C, Griffin J, Barton B, Jensen SE. 5S clavam biosynthetic genes are located in both the clavam and paralog gene clusters in Streptomyces clavuligerus. Chemistry & Biology. 14: 131-42. PMID 17317567 DOI: 10.1016/J.Chembiol.2006.11.012 |
0.67 |
|
| 2005 |
Bignell DR, Tahlan K, Colvin KR, Jensen SE, Leskiw BK. Expression of ccaR, encoding the positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus, is dependent on bldG. Antimicrobial Agents and Chemotherapy. 49: 1529-41. PMID 15793135 DOI: 10.1128/AAC.49.4.1529-1541.2005 |
0.409 |
|
| 2004 |
Tahlan K, Park HU, Jensen SE. Three unlinked gene clusters are involved in clavam metabolite biosynthesis in Streptomyces clavuligerus. Canadian Journal of Microbiology. 50: 803-10. PMID 15644894 DOI: 10.1139/w04-070 |
0.407 |
|
| 2004 |
Wang L, Tahlan K, Kaziuk TL, Alexander DC, Jensen SE. Transcriptional and translational analysis of the ccaR gene from Streptomyces clavuligerus. Microbiology (Reading, England). 150: 4137-45. PMID 15583166 DOI: 10.1099/mic.0.27245-0 |
0.383 |
|
| 2004 |
Tahlan K, Anders C, Jensen SE. The paralogous pairs of genes involved in clavulanic acid and clavam metabolite biosynthesis are differently regulated in Streptomyces clavuligerus. Journal of Bacteriology. 186: 6286-97. PMID 15342599 DOI: 10.1128/JB.186.18.6286-6297.2004 |
0.478 |
|
| 2004 |
Tahlan K, Park HU, Wong A, Beatty PH, Jensen SE. Two sets of paralogous genes encode the enzymes involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus. Antimicrobial Agents and Chemotherapy. 48: 930-9. PMID 14982786 DOI: 10.1128/Aac.48.3.930-939.2004 |
0.688 |
|
| 2004 |
Jensen SE, Wong A, Griffin A, Barton B. Streptomyces clavuligerus has a second copy of the proclavaminate amidinohydrolase gene. Antimicrobial Agents and Chemotherapy. 48: 514-20. PMID 14742203 DOI: 10.1128/AAC.48.2.514-520.2004 |
0.484 |
|
| 2004 |
Jensen SE, Paradkar AS, Mosher RH, Anders C, Beatty PH, Brumlik MJ, Griffin A, Barton B. Five additional genes are involved in clavulanic acid biosynthesis in Streptomyces clavuligerus. Antimicrobial Agents and Chemotherapy. 48: 192-202. PMID 14693539 DOI: 10.1128/Aac.48.1.192-202.2004 |
0.676 |
|
| 2002 |
Beatty PH, Jensen SE. Paenibacillus polymyxa produces fusaricidin-type antifungal antibiotics active against Leptosphaeria maculans, the causative agent of blackleg disease of canola. Canadian Journal of Microbiology. 48: 159-69. PMID 11958569 DOI: 10.1139/W02-002 |
0.589 |
|
| 2002 |
Trepanier NK, Jensen SE, Alexander DC, Leskiw BK. The positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is mistranslated in a bldA mutant. Microbiology (Reading, England). 148: 643-56. PMID 11882698 |
0.46 |
|
| 2001 |
Paradkar AS, Mosher RH, Anders C, Griffin A, Griffin J, Hughes C, Greaves P, Barton B, Jensen SE. Applications of gene replacement technology to Streptomyces clavuligerus strain development for clavulanic acid production. Applied and Environmental Microbiology. 67: 2292-7. PMID 11319114 DOI: 10.1128/AEM.67.5.2292-2297.2001 |
0.423 |
|
| 2001 |
Thai W, Paradkar AS, Jensen SE. Construction and analysis of ss-lactamase-inhibitory protein (BLIP) non-producer mutants of Streptomyces clavuligerus. Microbiology (Reading, England). 147: 325-35. PMID 11158349 |
0.42 |
|
| 2000 |
Jensen SE, Elder KJ, Aidoo KA, Paradkar AS. Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus. Antimicrobial Agents and Chemotherapy. 44: 720-6. PMID 10681345 DOI: 10.1128/AAC.44.3.720-726.2000 |
0.39 |
|
| 1999 |
Mosher RH, Paradkar AS, Anders C, Barton B, Jensen SE. Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus. Antimicrobial Agents and Chemotherapy. 43: 1215-24. PMID 10223939 DOI: 10.1128/aac.43.5.1215 |
0.48 |
|
| 1998 |
Alexander DC, Jensen SE. Investigation of the Streptomyces clavuligerus cephamycin C gene cluster and its regulation by the CcaR protein. Journal of Bacteriology. 180: 4068-79. PMID 9696752 DOI: 10.1128/jb.180.16.4068-4079.1998 |
0.316 |
|
| 1996 |
Paradkar AS, Aidoo KA, Wong A, Jensen SE. Molecular analysis of a beta-lactam resistance gene encoded within the cephamycin gene cluster of Streptomyces clavuligerus. Journal of Bacteriology. 178: 6266-74. PMID 8892828 DOI: 10.1128/jb.178.21.6266-6274.1996 |
0.356 |
|
| 1995 |
Paradkar AS, Jensen SE. Functional analysis of the gene encoding the clavaminate synthase 2 isoenzyme involved in clavulanic acid biosynthesis in Streptomyces clavuligerus. Journal of Bacteriology. 177: 1307-14. PMID 7868606 DOI: 10.1128/jb.177.5.1307-1314.1995 |
0.452 |
|
| 1994 |
Petrich AK, Leskiw BK, Paradkar AS, Jensen SE. Transcriptional mapping of the genes encoding the early enzymes of the cephamycin biosynthetic pathway of Streptomyces clavuligerus Gene. 142: 41-48. PMID 8181755 DOI: 10.1016/0378-1119(94)90352-2 |
0.345 |
|
| 1994 |
Aidoo KA, Wong A, Alexander DC, Rittammer RA, Jensen SE. Cloning, sequencing and disruption of a gene from Streptomyces clavuligerus involved in clavulanic acid biosynthesis. Gene. 147: 41-6. PMID 8088547 DOI: 10.1016/0378-1119(94)90036-1 |
0.498 |
|
| 1993 |
Durairaj M, Doran JL, Jensen SE. High-level expression of the Streptomyces clavuligerus isopenicillin N synthase gene in Escherichia coli. Applied and Environmental Microbiology. 58: 4038-41. PMID 1476443 DOI: 10.1128/aem.58.12.4038-4041.1992 |
0.305 |
|
| 1992 |
Petrich AK, Wu X, Roy KL, Jensen SE. Transcriptional analysis of the isopenicillin N synthase-encoding gene of Streptomyces clavuligerus. Gene. 111: 77-84. PMID 1547956 DOI: 10.1016/0378-1119(92)90605-O |
0.312 |
|
| 1990 |
Doran JL, Leskiw BK, Aippersbach S, Jensen SE. Isolation and characterization of a β-lactamase-inhibitory protein from Streptomyces clavuligerus and cloning and analysis of the corresponding gene Journal of Bacteriology. 172: 4909-4918. PMID 2203736 |
0.308 |
|
| 1990 |
Doran JL, Leskiw BK, Petrich AK, Westlake DWS, Jensen SE. Production of Streptomyces clavuligerus isopenicillin N synthase in Escherichia coli using two-cistron expression systems Journal of Industrial Microbiology. 5: 197-206. PMID 1366605 DOI: 10.1007/BF01569677 |
0.311 |
|
| 1989 |
Shiffman D, Mevarech M, Jensen SE, Cohen G, Aharonowitz Y. Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces. Molecular & General Genetics : Mgg. 214: 562-9. PMID 3216857 DOI: 10.1007/Bf00330495 |
0.43 |
|
| 1988 |
Leskiw BK, Aharonowitz Y, Mevarech M, Wolfe S, Vining LC, Westlake DWS, Jensen SE. Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus Gene. 62: 187-196. PMID 3130293 DOI: 10.1016/0378-1119(88)90557-4 |
0.358 |
|
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