Year |
Citation |
Score |
2019 |
Mensa-Wilmot K, Hoffman B, Wiedeman J, Sullenberger C, Sharma A. Kinetoplast Division Factors in a Trypanosome. Trends in Parasitology. PMID 30638954 DOI: 10.1016/J.Pt.2018.11.002 |
0.34 |
|
2018 |
Bachovchin KA, Sharma A, Bag S, Klug DM, Schneider KM, Singh B, Jalani HB, Buskes M, Mehta N, Tanghe S, Momper JD, Sciotti RJ, Rodriguez A, Mensa-Wilmot K, Pollastri MP, et al. Improvement of Aqueous Solubility of Lapatinib-derived Analogs: Identification of a Quinolinimine as a Lead for Human African Trypanosomiasis Drug Development. Journal of Medicinal Chemistry. PMID 30565932 DOI: 10.1021/Acs.Jmedchem.8B01365 |
0.301 |
|
2017 |
Devine W, Thomas SM, Erath J, Bachovchin KA, Lee PJ, Leed SE, Rodriguez A, Sciotti RJ, Mensa-Wilmot K, Pollastri MP. Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites. Acs Medicinal Chemistry Letters. 8: 350-354. PMID 28337329 DOI: 10.1021/Acsmedchemlett.7B00011 |
0.314 |
|
2016 |
Guyett PJ, Behera R, Ogata Y, Pollastri M, Mensa-Wilmot K. Novel Effects of Lapatinib Revealed in the African Trypanosome using Hypothesis-Generating Proteomics and Chemical Biology Strategies. Antimicrobial Agents and Chemotherapy. PMID 27872081 DOI: 10.1128/Aac.01865-16 |
0.393 |
|
2015 |
Woodring JL, Patel G, Erath J, Behera R, Lee PJ, Leed SE, Rodriguez A, Sciotti RJ, Mensa-Wilmot K, Pollastri MP. EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA. Medchemcomm. 6: 339-346. PMID 25685309 DOI: 10.1039/C4Md00441H |
0.32 |
|
2013 |
Katiyar S, Kufareva I, Behera R, Thomas SM, Ogata Y, Pollastri M, Abagyan R, Mensa-Wilmot K. Lapatinib-binding protein kinases in the African trypanosome: identification of cellular targets for kinase-directed chemical scaffolds. Plos One. 8: e56150. PMID 23437089 DOI: 10.1371/Journal.Pone.0056150 |
0.313 |
|
2010 |
Subramanya S, Armah DA, Mensa-Wilmot K. Trypanosoma brucei: reduction of GPI-phospholipase C protein during differentiation is dependent on replication of newly transformed cells. Experimental Parasitology. 125: 222-9. PMID 20109448 DOI: 10.1016/J.Exppara.2010.01.014 |
0.317 |
|
2010 |
Subramanya S, Mensa-Wilmot K. Diacylglycerol-stimulated endocytosis of transferrin in trypanosomatids is dependent on tyrosine kinase activity. Plos One. 5: e8538. PMID 20049089 DOI: 10.1371/Journal.Pone.0008538 |
0.368 |
|
2010 |
Duffy J, Patham B, Mensa-Wilmot K. Discovery of functional motifs in h-regions of trypanosome signal sequences. The Biochemical Journal. 426: 135-45. PMID 20017734 DOI: 10.1042/Bj20091277 |
0.397 |
|
2009 |
Patham B, Duffy J, Lane A, Davis RC, Wipf P, Fewell SW, Brodsky JL, Mensa-Wilmot K. Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities. The Biochemical Journal. 419: 507-17. PMID 19196237 DOI: 10.1042/Bj20081787 |
0.373 |
|
2009 |
Subramanya S, Hardin CF, Steverding D, Mensa-Wilmot K. Glycosylphosphatidylinositol-specific phospholipase C regulates transferrin endocytosis in the African trypanosome. The Biochemical Journal. 417: 685-94. PMID 18785878 DOI: 10.1042/Bj20080167 |
0.38 |
|
2006 |
Stanton JD, Mensa-Wilmot K. AUG-proximal nucleotides regulate protein synthesis in Leishmania tropica. Molecular Microbiology. 61: 691-703. PMID 16787450 DOI: 10.1111/J.1365-2958.2006.05228.X |
0.42 |
|
2006 |
Subramanya S, Mensa-Wilmot K. Regulated cleavage of intracellular glycosylphosphatidylinositol in a trypanosome. Peroxisome-to-endoplasmic reticulum translocation of a phospholipase C. The Febs Journal. 273: 2110-26. PMID 16649989 DOI: 10.1111/J.1742-4658.2006.05225.X |
0.388 |
|
2005 |
Zheng Z, Tweten RK, Mensa-Wilmot K. Intracellular glycosylphosphatidylinositols accumulate on endosomes: toxicity of alpha-toxin to Leishmania major. Eukaryotic Cell. 4: 556-66. PMID 15755918 DOI: 10.1128/Ec.4.3.556-566.2005 |
0.304 |
|
2004 |
Zheng Z, Butler KD, Tweten RK, Mensa-Wilmot K. Endosomes, glycosomes, and glycosylphosphatidylinositol catabolism in Leishmania major. The Journal of Biological Chemistry. 279: 42106-13. PMID 15254033 DOI: 10.1074/Jbc.M403780200 |
0.412 |
|
2002 |
Stanton JD, Rashid MB, Mensa-Wilmot K. Cysteine-less glycosylphosphatidylinositol-specific phospholipase C is inhibited competitively by a thiol reagent: evidence for glyco-mimicry by p-chloromercuriphenylsulphonate. The Biochemical Journal. 366: 281-8. PMID 12010122 DOI: 10.1042/Bj20020367 |
0.344 |
|
2000 |
Armah DA, Mensa-Wilmot K. Tetramerization of glycosylphosphatidylinositol-specific phospholipase C from Trypanosoma brucei. Journal of Biological Chemistry. 275: 19334-19342. PMID 10764777 DOI: 10.1074/Jbc.M001798200 |
0.347 |
|
2000 |
Rashid MB, Mensa-Wilmot K. Novel kanamycin/neomycin phosphotransferase cassette increases transformation efficiency in E. coli. Biotechniques. 28: 90-94. PMID 10649776 DOI: 10.2144/00281St03 |
0.302 |
|
1999 |
Rashid MB, Russell M, Mensa-Wilmot K. Roles of Gln81 and Cys80 in catalysis by glycosylphosphatidylinositol-phospholipase C from Trypanosoma brucei Febs Journal. 264: 914-920. PMID 10491140 DOI: 10.1046/J.1432-1327.1999.00690.X |
0.346 |
|
1999 |
Mensa-Wilmot K, Garg N, McGwire BS, Lu HG, Zhong L, Armah DA, LeBowitz JH, Chang KP. Roles of free GPIs in amastigotes of Leishmania. Molecular and Biochemical Parasitology. 99: 103-16. PMID 10215028 DOI: 10.1016/S0166-6851(99)00003-1 |
0.334 |
|
1999 |
Armah DA, Mensa-Wilmot K. Protein S-Myristoylation inLeishmaniaRevealed with a Heterologous Reporter☆ Biochemical and Biophysical Research Communications. 256: 569-572. PMID 10080938 DOI: 10.1006/Bbrc.1999.0376 |
0.372 |
|
1999 |
Armah DA, Mensa-Wilmot K. S-myristoylation of a glycosylphosphatidylinositol-specific phospholipase C in Trypanosoma brucei. Journal of Biological Chemistry. 274: 5931-5938. PMID 10026218 DOI: 10.1074/Jbc.274.9.5931 |
0.364 |
|
1998 |
Teilhet M, Rashid MB, Hawk A, Al-Qahtani A, Mensa-Wilmot K. Effect of short 5' UTRs on protein synthesis in two biological kingdoms. Gene. 222: 91-97. PMID 9813258 DOI: 10.1016/S0378-1119(98)00470-3 |
0.581 |
|
1998 |
Al-Qahtani A, Teilhet M, Mensa-Wilmot K. Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania. Biochemical Journal. 331: 521-529. PMID 9531493 DOI: 10.1042/Bj3310521 |
0.572 |
|
1997 |
Morris JC, Mensa-Wilmot K. Role of 2,6-dideoxy-2,6-diaminoglucose in activation of a eukaryotic phospholipase C by aminoglycoside antibiotics Journal of Biological Chemistry. 272: 29554-29559. PMID 9368017 DOI: 10.1074/Jbc.272.47.29554 |
0.322 |
|
1997 |
Garg N, Tarleton RL, Mensa-Wilmot K. Proteins with glycosylphosphatidylinositol (GPI) signal sequences have divergent fates during a GPI deficiency. GPIs are essential for nuclear division in Trypanosoma cruzi. The Journal of Biological Chemistry. 272: 12482-91. PMID 9139697 DOI: 10.1074/Jbc.272.19.12482 |
0.421 |
|
1996 |
Morris JC, Ping-Sheng L, Zhai HX, Shen TY, Mensa-Wilmot K. Phosphatidylinositol phospholipase C is activated allosterically by the aminoglycoside G418. 2-deoxy-2-fluoro-scyllo-inositol-1-O-dodecylphosphonate and its analogs inhibit glycosylphosphatidylinositol phospholipase C. The Journal of Biological Chemistry. 271: 15468-77. PMID 8663028 DOI: 10.1074/Jbc.271.26.15468 |
0.307 |
|
1996 |
Al-Qahtani A, Mensa-Wilmot K. A 5′ Untranslated Region Which Directs Accurate and Robust Translation By Prokaryotic and Mammalian Ribosomes Nucleic Acids Research. 24: 1173-1174. PMID 8604355 DOI: 10.1093/Nar/24.6.1173 |
0.345 |
|
1995 |
Mensa-Wilmot K, Morris JC, al-Qahtani A, Englund PT. Purification and use of recombinant glycosylphosphatidylinositol-phospholipase C. Methods in Enzymology. 250: 641-55. PMID 7651183 DOI: 10.1016/0076-6879(95)50102-9 |
0.473 |
|
1995 |
Zhai H, Lei P, Morris JC, Mensa-Wilmot K, Shen TY. Synthesis of 2-deoxy-2-fluorinated inositol-1-0-dodecylphosphonates as inhibitors of glycosyl phosphatidylinositol phospholipase C Tetrahedron Letters. 36: 7403-7406. DOI: 10.1016/0040-4039(95)01579-5 |
0.309 |
|
1994 |
Mensa-Wilmot K, LeBowitz JH, Chang KP, Al-Qahtani A, McGwire BS, Tucker S, Morris JC. A glycosylphosphatidylinositol (GPI)-negative phenotype produced in Leishmania major by GPI phospholipase C from Trypanosoma brucei: Topography of two GPI pathways Journal of Cell Biology. 124: 935-947. PMID 8132715 DOI: 10.1083/Jcb.124.6.935 |
0.406 |
|
1992 |
Mensa-Wilmot K, Englund PT. Non-fusion proteins expressed in E. coli: detection by alpha-complementation (blue/white selection). Nucleic Acids Research. 20: 143. PMID 1738595 DOI: 10.1093/Nar/20.1.143 |
0.519 |
|
1992 |
Mensa-Wilmot K, Englund PT. Glycosyl phosphatidylinositol-specific phospholipase C of Trypanosoma brucei: expression in Escherichia coli. Molecular and Biochemical Parasitology. 56: 311-21. PMID 1362451 DOI: 10.1016/0166-6851(92)90180-R |
0.533 |
|
1990 |
Mensa-Wilmot K, Hereld D, Englund PT. Genomic organization, chromosomal localization, and developmentally regulated expression of the glycosyl-phosphatidylinositol-specific phospholipase C of Trypanosoma brucei. Molecular and Cellular Biology. 10: 720-6. PMID 1688997 DOI: 10.1128/Mcb.10.2.720 |
0.535 |
|
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