Paul T. Schumacker - Publications

University of Chicago, Chicago, IL 
Cell Biology, Pathology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Waypa GB, Schumacker PT. Roles of HIF1 and HIF2 in pulmonary hypertension: it all depends on the context. The European Respiratory Journal. 54. PMID 31831673 DOI: 10.1183/13993003.01929-2019  0.48
2019 Weinberg SE, Singer BD, Steinert EM, Martinez CA, Mehta MM, Martínez-Reyes I, Gao P, Helmin KA, Abdala-Valencia H, Sena LA, Schumacker PT, Turka LA, Chandel NS. Mitochondrial complex III is essential for suppressive function of regulatory T cells. Nature. PMID 30626970 DOI: 10.1038/s41586-018-0846-z  0.32
2018 Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen JM, Ben-Sahra I, Gius DR, Charvet LY, Chandel NS, Schumacker PT, Thorp EB. Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair. Cell Metabolism. PMID 30595481 DOI: 10.1016/j.cmet.2018.12.004  0.32
2017 Sala MA, Chen C, Zhang Q, Do-Umehara HC, Wu W, Misharin AV, Waypa GB, Fang D, Budinger GRS, Liu S, Chandel NS, Schumacker PT, Sznajder JI, Liu J. JNK2 Upregulates Hypoxia-Inducible Factors and Contributes to Hypoxia-Induced Erythropoiesis and Pulmonary Hypertension. The Journal of Biological Chemistry. PMID 29118187 DOI: 10.1074/jbc.RA117.000440  0.48
2017 Smith KA, Waypa GB, Schumacker PT. Redox signaling during hypoxia in mammalian cells. Redox Biology. 13: 228-234. PMID 28595160 DOI: 10.1016/j.redox.2017.05.020  0.48
2017 Ansó E, Weinberg SE, Diebold LP, Thompson BJ, Malinge S, Schumacker PT, Liu X, Zhang Y, Shao Z, Steadman M, Marsh KM, Xu J, Crispino JD, Chandel NS. The mitochondrial respiratory chain is essential for haematopoietic stem cell function. Nature Cell Biology. PMID 28504706 DOI: 10.1038/ncb3529  0.32
2016 Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, Julien JP, Goldman RD, Opal P. Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in Giant Axonal Neuropathy. Human Molecular Genetics. PMID 27000625 DOI: 10.1093/hmg/ddw081  0.32
2016 Waypa GB, Smith KA, Schumacker PT. O2 sensing, mitochondria and ROS signaling: The fog is lifting. Molecular Aspects of Medicine. PMID 26776678 DOI: 10.1016/j.mam.2016.01.002  0.48
2015 Smith KA, Yuan JX, Schumacker PT. MicroRNAs and PARP: co-conspirators with ROS in pulmonary hypertension. Focus on "miR-223 reverses experimental pulmonary arterial hypertension". American Journal of Physiology. Cell Physiology. 309: C361-2. PMID 26201953 DOI: 10.1152/ajpcell.00209.2015  0.44
2015 Datta A, Kim GA, Taylor JM, Gugino SF, Farrow KN, Schumacker PT, Berkelhamer SK. Mouse Lung Development and NOX1 Induction During Hyperoxia Are Developmentally Regulated and Mitochondrial ROS-Dependent. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00176.2014. PMID 26092998 DOI: 10.1152/ajplung.00176.2014  0.44
2015 Guzman JN, Sanchez-Padilla J, Wokosin D, Kondapalli J, Ilijic E, Schumacker PT, Surmeier DJ. Corrigendum: Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature. 521: 380. PMID 25993967 DOI: 10.1038/nature14487  0.44
2015 Takeuchi T, Schumacker PT, Kozmin SA. Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity. Journal of the American Chemical Society. 137: 564-7. PMID 25469852 DOI: 10.1021/ja5101257  0.44
2015 Cheresh P, Morales-Nebreda L, Kim SJ, Yeldandi A, Williams DB, Cheng Y, Mutlu GM, Budinger GR, Ridge K, Schumacker PT, Bohr VA, Kamp DW. Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice. American Journal of Respiratory Cell and Molecular Biology. 52: 25-36. PMID 24918270 DOI: 10.1165/rcmb.2014-0038OC  0.44
2014 Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, ... ... Schumacker PT, et al. The 'mitoflash' probe cpYFP does not respond to superoxide. Nature. 514: E12-4. PMID 25341790 DOI: 10.1038/nature13858  0.44
2014 Sanchez-Padilla J, Guzman JN, Ilijic E, Kondapalli J, Galtieri DJ, Yang B, Schieber S, Oertel W, Wokosin D, Schumacker PT, Surmeier DJ. Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase. Nature Neuroscience. 17: 832-40. PMID 24816140 DOI: 10.1038/nn.3717  0.44
2014 Schumacker PT, Gillespie MN, Nakahira K, Choi AM, Crouser ED, Piantadosi CA, Bhattacharya J. Mitochondria in lung biology and pathology: more than just a powerhouse. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L962-74. PMID 24748601 DOI: 10.1152/ajplung.00073.2014  0.44
2014 Kim SJ, Cheresh P, Williams D, Cheng Y, Ridge K, Schumacker PT, Weitzman S, Bohr VA, Kamp DW. Mitochondria-targeted Ogg1 and aconitase-2 prevent oxidant-induced mitochondrial DNA damage in alveolar epithelial cells. The Journal of Biological Chemistry. 289: 6165-76. PMID 24429287 DOI: 10.1074/jbc.M113.515130  0.44
2014 Ball MK, Waypa GB, Mungai PT, Nielsen JM, Czech L, Dudley VJ, Beussink L, Dettman RW, Berkelhamer SK, Steinhorn RH, Shah SJ, Schumacker PT. Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α. American Journal of Respiratory and Critical Care Medicine. 189: 314-24. PMID 24251580 DOI: 10.1164/rccm.201302-0302OC  0.44
2013 Waypa GB, Osborne SW, Marks JD, Berkelhamer SK, Kondapalli J, Schumacker PT. Sirtuin 3 deficiency does not augment hypoxia-induced pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 49: 885-91. PMID 24047466 DOI: 10.1165/rcmb.2013-0191OC  0.44
2013 Sabharwal SS, Waypa GB, Marks JD, Schumacker PT. Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling. The Biochemical Journal. 456: 337-46. PMID 24044889 DOI: 10.1042/BJ20130740  0.44
2013 Hanna C, Hubchak SC, Liang X, Rozen-Zvi B, Schumacker PT, Hayashida T, Schnaper HW. Hypoxia-inducible factor-2α and TGF-β signaling interact to promote normoxic glomerular fibrogenesis. American Journal of Physiology. Renal Physiology. 305: F1323-31. PMID 23946285 DOI: 10.1152/ajprenal.00155.2013  0.44
2013 Dryanovski DI, Guzman JN, Xie Z, Galteri DJ, Volpicelli-Daley LA, Lee VM, Miller RJ, Schumacker PT, Surmeier DJ. Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10154-64. PMID 23761910 DOI: 10.1523/JNEUROSCI.5311-12.2013  0.44
2013 Schriewer JM, Peek CB, Bass J, Schumacker PT. ROS-mediated PARP activity undermines mitochondrial function after permeability transition pore opening during myocardial ischemia-reperfusion. Journal of the American Heart Association. 2: e000159. PMID 23598272 DOI: 10.1161/JAHA.113.000159  0.44
2013 Shah MR, Wedgwood S, Czech L, Kim GA, Lakshminrusimha S, Schumacker PT, Steinhorn RH, Farrow KN. Cyclic stretch induces inducible nitric oxide synthase and soluble guanylate cyclase in pulmonary artery smooth muscle cells. International Journal of Molecular Sciences. 14: 4334-48. PMID 23429274 DOI: 10.3390/ijms14024334  0.44
2013 Sena LA, Li S, Jairaman A, Prakriya M, Ezponda T, Hildeman DA, Wang CR, Schumacker PT, Licht JD, Perlman H, Bryce PJ, Chandel NS. Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. Immunity. 38: 225-36. PMID 23415911 DOI: 10.1016/j.immuni.2012.10.020  0.44
2013 Waypa GB, Marks JD, Guzy RD, Mungai PT, Schriewer JM, Dokic D, Ball MK, Schumacker PT. Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation. American Journal of Respiratory and Critical Care Medicine. 187: 424-32. PMID 23328522 DOI: 10.1164/rccm.201207-1294OC  0.44
2013 Surmeier DJ, Schumacker PT. Calcium, bioenergetics, and neuronal vulnerability in Parkinson's disease. The Journal of Biological Chemistry. 288: 10736-41. PMID 23086948 DOI: 10.1074/jbc.R112.410530  0.44
2012 Surmeier DJ, Guzman JN, Sanchez J, Schumacker PT. Physiological phenotype and vulnerability in Parkinson's disease. Cold Spring Harbor Perspectives in Medicine. 2: a009290. PMID 22762023 DOI: 10.1101/cshperspect.a009290  0.44
2012 Farrow KN, Lee KJ, Perez M, Schriewer JM, Wedgwood S, Lakshminrusimha S, Smith CL, Steinhorn RH, Schumacker PT. Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells. Antioxidants & Redox Signaling. 17: 460-70. PMID 22229392 DOI: 10.1089/ars.2011.4184  0.44
2011 Mungai PT, Waypa GB, Jairaman A, Prakriya M, Dokic D, Ball MK, Schumacker PT. Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels. Molecular and Cellular Biology. 31: 3531-45. PMID 21670147 DOI: 10.1128/MCB.05124-11  0.44
2011 Murphy MP, Holmgren A, Larsson NG, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SG, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT, Winterbourn CC. Unraveling the biological roles of reactive oxygen species. Cell Metabolism. 13: 361-6. PMID 21459321 DOI: 10.1016/j.cmet.2011.03.010  0.44
2011 Loor G, Kondapalli J, Iwase H, Chandel NS, Waypa GB, Guzy RD, Vanden Hoek TL, Schumacker PT. Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. Biochimica Et Biophysica Acta. 1813: 1382-94. PMID 21185334 DOI: 10.1016/j.bbamcr.2010.12.008  1
2011 Budinger GR, Mutlu GM, Urich D, Soberanes S, Buccellato LJ, Hawkins K, Chiarella SE, Radigan KA, Eisenbart J, Agrawal H, Berkelhamer S, Hekimi S, Zhang J, Perlman H, Schumacker PT, et al. Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. American Journal of Respiratory and Critical Care Medicine. 183: 1043-54. PMID 20959557 DOI: 10.1164/rccm.201002-0181OC  0.32
2011 Wedgwood S, Lakshminrusimha S, Fukai T, Russell JA, Schumacker PT, Steinhorn RH. Hydrogen peroxide regulates extracellular superoxide dismutase activity and expression in neonatal pulmonary hypertension. Antioxidants & Redox Signaling. 15: 1497-506. PMID 20919937 DOI: 10.1089/ars.2010.3630  0.44
2010 Guzman JN, Sanchez-Padilla J, Wokosin D, Kondapalli J, Ilijic E, Schumacker PT, Surmeier DJ. Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature. 468: 696-700. PMID 21068725 DOI: 10.1038/nature09536  0.44
2010 Loor G, Kondapalli J, Schriewer JM, Chandel NS, Vanden Hoek TL, Schumacker PT. Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis. Free Radical Biology & Medicine. 49: 1925-36. PMID 20937380 DOI: 10.1016/j.freeradbiomed.2010.09.021  0.44
2010 Farrow KN, Wedgwood S, Lee KJ, Czech L, Gugino SF, Lakshminrusimha S, Schumacker PT, Steinhorn RH. Mitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn. Respiratory Physiology & Neurobiology. 174: 272-81. PMID 20804862 DOI: 10.1016/j.resp.2010.08.018  0.44
2010 Waypa GB, Schumacker PT. Hypoxia-induced changes in pulmonary and systemic vascular resistance: where is the O2 sensor? Respiratory Physiology & Neurobiology. 174: 201-11. PMID 20713189 DOI: 10.1016/j.resp.2010.08.007  0.48
2010 Jung HJ, Shim JS, Lee J, Song YM, Park KC, Choi SH, Kim ND, Yoon JH, Mungai PT, Schumacker PT, Kwon HJ. Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing. The Journal of Biological Chemistry. 285: 11584-95. PMID 20145250 DOI: 10.1074/jbc.M109.087809  0.44
2010 Waypa GB, Marks JD, Guzy R, Mungai PT, Schriewer J, Dokic D, Schumacker PT. Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells. Circulation Research. 106: 526-35. PMID 20019331 DOI: 10.1161/CIRCRESAHA.109.206334  0.44
2010 Desireddi JR, Farrow KN, Marks JD, Waypa GB, Schumacker PT. Hypoxia increases ROS signaling and cytosolic Ca(2+) in pulmonary artery smooth muscle cells of mouse lungs slices. Antioxidants & Redox Signaling. 12: 595-602. PMID 19747064 DOI: 10.1089/ars.2009.2862  0.44
2010 Chi AY, Waypa GB, Mungai PT, Schumacker PT. Prolonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cells. Antioxidants & Redox Signaling. 12: 603-10. PMID 19747063 DOI: 10.1089/ars.2009.2861  0.48
2009 Soberanes S, Urich D, Baker CM, Burgess Z, Chiarella SE, Bell EL, Ghio AJ, De Vizcaya-Ruiz A, Liu J, Ridge KM, Kamp DW, Chandel NS, Schumacker PT, Mutlu GM, Budinger GR. Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution. The Journal of Biological Chemistry. 284: 2176-86. PMID 19033436 DOI: 10.1074/jbc.M808844200  0.44
2009 Klimova TA, Bell EL, Shroff EH, Weinberg FD, Snyder CM, Dimri GP, Schumacker PT, Budinger GR, Chandel NS. Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 783-94. PMID 18948382 DOI: 10.1096/fj.08-114256  0.32
2008 Ulanovskaya OA, Janjic J, Suzuki M, Sabharwal SS, Schumacker PT, Kron SJ, Kozmin SA. Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Nature Chemical Biology. 4: 418-24. PMID 18516048 DOI: 10.1038/nchembio.94  0.44
2008 Evens AM, Schumacker PT, Helenowski IB, Singh AT, Dokic D, Keswani A, Kordeluk E, Raji A, Winter JN, Jovanovic BD, Holmgren A, Nelson BP, Gordon LI. Hypoxia inducible factor-alpha activation in lymphoma and relationship to the thioredoxin family. British Journal of Haematology. 141: 676-80. PMID 18422776 DOI: 10.1111/j.1365-2141.2008.07093.x  0.44
2008 Vadász I, Dada LA, Briva A, Trejo HE, Welch LC, Chen J, Tóth PT, Lecuona E, Witters LA, Schumacker PT, Chandel NS, Seeger W, Sznajder JI. AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis. The Journal of Clinical Investigation. 118: 752-62. PMID 18188452 DOI: 10.1172/JCI29723  0.44
2008 Waypa GB, Schumacker PT. Oxygen sensing in hypoxic pulmonary vasoconstriction: using new tools to answer an age-old question. Experimental Physiology. 93: 133-8. PMID 17993507 DOI: 10.1113/expphysiol.2007.041236  0.48
2008 Farrow KN, Groh BS, Schumacker PT, Lakshminrusimha S, Czech L, Gugino SF, Russell JA, Steinhorn RH. Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cells. Circulation Research. 102: 226-33. PMID 17991881 DOI: 10.1161/CIRCRESAHA.107.161463  0.44
2008 Guzy RD, Sharma B, Bell E, Chandel NS, Schumacker PT. Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis. Molecular and Cellular Biology. 28: 718-31. PMID 17967865 DOI: 10.1128/MCB.01338-07  1
2007 Iwase H, Robin E, Guzy RD, Mungai PT, Vanden Hoek TL, Chandel NS, Levraut J, Schumacker PT. Nitric oxide during ischemia attenuates oxidant stress and cell death during ischemia and reperfusion in cardiomyocytes. Free Radical Biology & Medicine. 43: 590-9. PMID 17640569 DOI: 10.1016/j.freeradbiomed.2007.05.017  0.44
2007 Guzy RD, Mack MM, Schumacker PT. Mitochondrial complex III is required for hypoxia-induced ROS production and gene transcription in yeast. Antioxidants & Redox Signaling. 9: 1317-28. PMID 17627464 DOI: 10.1089/ars.2007.1708  0.44
2007 Bell EL, Klimova TA, Eisenbart J, Schumacker PT, Chandel NS. Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia. Molecular and Cellular Biology. 27: 5737-45. PMID 17562866 DOI: 10.1128/MCB.02265-06  0.32
2007 Robin E, Guzy RD, Loor G, Iwase H, Waypa GB, Marks JD, Hoek TL, Schumacker PT. Oxidant stress during simulated ischemia primes cardiomyocytes for cell death during reperfusion. The Journal of Biological Chemistry. 282: 19133-43. PMID 17488710 DOI: 10.1074/jbc.M701917200  0.44
2006 Waypa GB, Guzy R, Mungai PT, Mack MM, Marks JD, Roe MW, Schumacker PT. Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells. Circulation Research. 99: 970-8. PMID 17008601 DOI: 10.1161/01.RES.0000247068.75808.3f  0.44
2006 Guzy RD, Schumacker PT. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Experimental Physiology. 91: 807-19. PMID 16857720 DOI: 10.1113/expphysiol.2006.033506  1
2006 Waypa GB, Schumacker PT. Role for mitochondrial reactive oxygen species in hypoxic pulmonary vasoconstriction. Novartis Foundation Symposium. 272: 176-92; discussion 1. PMID 16686436  0.48
2006 Ali MH, Mungai PT, Schumacker PT. Stretch-induced phosphorylation of focal adhesion kinase in endothelial cells: role of mitochondrial oxidants. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L38-45. PMID 16510472 DOI: 10.1152/ajplung.00287.2004  0.44
2005 Li D, Marks JD, Schumacker PT, Young RM, Brorson JR. Physiological hypoxia promotes survival of cultured cortical neurons. The European Journal of Neuroscience. 22: 1319-26. PMID 16190887 DOI: 10.1111/j.1460-9568.2005.04335.x  0.44
2005 Guzy RD, Hoyos B, Robin E, Chen H, Liu L, Mansfield KD, Simon MC, Hammerling U, Schumacker PT. Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metabolism. 1: 401-8. PMID 16054089 DOI: 10.1016/j.cmet.2005.05.001  0.44
2005 Mansfield KD, Guzy RD, Pan Y, Young RM, Cash TP, Schumacker PT, Simon MC. Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation. Cell Metabolism. 1: 393-9. PMID 16054088 DOI: 10.1016/j.cmet.2005.05.003  0.44
2005 Waypa GB, Schumacker PT. Hypoxic pulmonary vasoconstriction: redox events in oxygen sensing. Journal of Applied Physiology (Bethesda, Md. : 1985). 98: 404-14. PMID 15591310 DOI: 10.1152/japplphysiol.00722.2004  0.48
2004 Kweon GR, Marks JD, Krencik R, Leung EH, Schumacker PT, Hyland K, Kang UJ. Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells. The Journal of Biological Chemistry. 279: 51783-92. PMID 15469939 DOI: 10.1074/jbc.M407336200  0.44
2004 Shao ZH, Vanden Hoek TL, Li CQ, Schumacker PT, Becker LB, Chan KC, Qin Y, Yin JJ, Yuan CS. Synergistic effect of Scutellaria baicalensis and grape seed proanthocyanidins on scavenging reactive oxygen species in vitro. The American Journal of Chinese Medicine. 32: 89-95. PMID 15154288 DOI: 10.1142/S0192415X04001722  0.44
2004 Ali MH, Pearlstein DP, Mathieu CE, Schumacker PT. Mitochondrial requirement for endothelial responses to cyclic strain: implications for mechanotransduction. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L486-96. PMID 15090367 DOI: 10.1152/ajplung.00389.2003  0.4
2004 Shao ZH, Xie JT, Vanden Hoek TL, Mehendale S, Aung H, Li CQ, Qin Y, Schumacker PT, Becker LB, Yuan CS. Antioxidant effects of American ginseng berry extract in cardiomyocytes exposed to acute oxidant stress. Biochimica Et Biophysica Acta. 1670: 165-71. PMID 14980443 DOI: 10.1016/j.bbagen.2003.12.001  0.44
2003 Shao ZH, Vanden Hoek TL, Xie J, Wojcik K, Chan KC, Li CQ, Hamann K, Qin Y, Schumacker PT, Becker LB, Yuan CS. Grape seed proanthocyanidins induce pro-oxidant toxicity in cardiomyocytes. Cardiovascular Toxicology. 3: 331-9. PMID 14734830  0.44
2003 Shao ZH, Becker LB, Vanden Hoek TL, Schumacker PT, Li CQ, Zhao D, Wojcik K, Anderson T, Qin Y, Dey L, Yuan CS. Grape seed proanthocyanidin extract attenuates oxidant injury in cardiomyocytes. Pharmacological Research. 47: 463-9. PMID 12741998  0.44
2003 Levraut J, Iwase H, Shao ZH, Vanden Hoek TL, Schumacker PT. Cell death during ischemia: relationship to mitochondrial depolarization and ROS generation. American Journal of Physiology. Heart and Circulatory Physiology. 284: H549-58. PMID 12388276 DOI: 10.1152/ajpheart.00708.2002  0.44
2003 Lebuffe G, Schumacker PT, Shao ZH, Anderson T, Iwase H, Vanden Hoek TL. ROS and NO trigger early preconditioning: relationship to mitochondrial KATP channel. American Journal of Physiology. Heart and Circulatory Physiology. 284: H299-308. PMID 12388274 DOI: 10.1152/ajpheart.00706.2002  0.44
2002 Waypa GB, Marks JD, Mack MM, Boriboun C, Mungai PT, Schumacker PT. Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes. Circulation Research. 91: 719-26. PMID 12386149 DOI: 10.1161/01.RES.0000036751.04896.F1  0.44
2002 Waypa GB, Schumacker PT. O(2) sensing in hypoxic pulmonary vasoconstriction: the mitochondrial door re-opens. Respiratory Physiology & Neurobiology. 132: 81-91. PMID 12126697  0.48
2002 Ali MH, Schumacker PT. Endothelial responses to mechanical stress: where is the mechanosensor? Critical Care Medicine. 30: S198-206. PMID 12004236  0.4
2002 Kulisz A, Chen N, Chandel NS, Shao Z, Schumacker PT. Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1324-9. PMID 12003789 DOI: 10.1152/ajplung.00326.2001  0.32
2002 Pearlstein DP, Ali MH, Mungai PT, Hynes KL, Gewertz BL, Schumacker PT. Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 566-73. PMID 11950692 DOI: 10.1161/01.ATV.0000012262.76205.6A  0.44
2002 Shao ZH, Vanden Hoek TL, Qin Y, Becker LB, Schumacker PT, Li CQ, Dey L, Barth E, Halpern H, Rosen GM, Yuan CS. Baicalein attenuates oxidant stress in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 282: H999-H1006. PMID 11834498 DOI: 10.1152/ajpheart.00163.2001  0.44
1999 Ali MH, Schlidt SA, Chandel NS, Hynes KL, Schumacker PT, Gewertz BL. Endothelial permeability and IL-6 production during hypoxia: role of ROS in signal transduction. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L1057-L1065. PMID 29592305 DOI: 10.1152/ajplung.1999.277.5.L1057  0.4
1999 Yao Z, Tong J, Tan X, Li C, Shao Z, Kim WC, Vanden Hoek TL, Becker LB, Head CA, Schumacker PT. Role of reactive oxygen species in acetylcholine-induced preconditioning in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 277: H2504-H2509. PMID 29592292 DOI: 10.1152/ajpheart.1999.277.6.H2504  0.44
1999 Becker LB, Vanden Hoek TL, Shao ZH, Li CQ, Schumacker PT. Generation of superoxide in cardiomyocytes during ischemia before reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 277: H2240-H2246. PMID 29592283 DOI: 10.1152/ajpheart.1999.277.6.H2240  0.44
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