Year |
Citation |
Score |
2024 |
Liu D, Hsieh CL, Lieber MR. The RNA tether model for human chromosomal translocation fragile zones. Trends in Biochemical Sciences. PMID 38490833 DOI: 10.1016/j.tibs.2024.02.003 |
0.326 |
|
2021 |
Liu D, Loh YE, Hsieh CL, Lieber MR. Mechanistic basis for chromosomal translocations at the E2A gene and its broader relevance to human B cell malignancies. Cell Reports. 36: 109387. PMID 34260910 DOI: 10.1016/j.celrep.2021.109387 |
0.388 |
|
2020 |
Anne Esguerra Z, Watanabe G, Okitsu CY, Hsieh CL, Lieber MR. DNA-PKcs chemical inhibition versus genetic mutation: Impact on the junctional repair steps of V(D)J recombination. Molecular Immunology. 120: 93-100. PMID 32113132 DOI: 10.1016/J.Molimm.2020.01.018 |
0.393 |
|
2018 |
Hsieh CL. Novel Lines of Evidence for the Asymmetric Strand Displacement Model of Mitochondrial DNA Replication. Molecular and Cellular Biology. PMID 30397074 DOI: 10.1128/Mcb.00406-18 |
0.379 |
|
2015 |
Okitsu CY, Hsieh CL. Sensitivity and specificity of immunoprecipitation of DNA containing 5-Methylcytosine. Bmc Research Notes. 8: 102. PMID 25888776 DOI: 10.1186/S13104-015-1069-0 |
0.395 |
|
2015 |
Lu Z, Lieber MR, Tsai AG, Pardo CE, Müschen M, Kladde MP, Hsieh CL. Human lymphoid translocation fragile zones are hypomethylated and have accessible chromatin. Molecular and Cellular Biology. 35: 1209-22. PMID 25624348 DOI: 10.1128/Mcb.01085-14 |
0.488 |
|
2014 |
Han L, Masani S, Hsieh CL, Yu K. DNA ligase I is not essential for mammalian cell viability. Cell Reports. 7: 316-20. PMID 24726358 DOI: 10.1016/j.celrep.2014.03.024 |
0.354 |
|
2014 |
Hsieh CL. Dynamics of DNA Methylation Patterns in Human Cells Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00095-7 |
0.381 |
|
2013 |
Okitsu CY, Van Den Berg DJ, Lieber MR, Hsieh CL. Reproducibility and reliability of SNP analysis using human cellular DNA at or near nanogram levels. Bmc Research Notes. 6: 515. PMID 24314330 DOI: 10.1186/1756-0500-6-515 |
0.411 |
|
2013 |
Hong EE, Okitsu CY, Smith AD, Hsieh CL. Regionally specific and genome-wide analyses conclusively demonstrate the absence of CpG methylation in human mitochondrial DNA. Molecular and Cellular Biology. 33: 2683-90. PMID 23671186 DOI: 10.1128/Mcb.00220-13 |
0.445 |
|
2013 |
Hsieh JC, Van Den Berg D, Kang H, Hsieh CL, Lieber MR. Large chromosome deletions, duplications, and gene conversion events accumulate with age in normal human colon crypts. Aging Cell. 12: 269-79. PMID 23425690 DOI: 10.1111/Acel.12053 |
0.368 |
|
2013 |
Cui X, Lu Z, Kurosawa A, Klemm L, Bagshaw AT, Tsai AG, Gemmell N, Müschen M, Adachi N, Hsieh CL, Lieber MR. Both CpG methylation and activation-induced deaminase are required for the fragility of the human bcl-2 major breakpoint region: implications for the timing of the breaks in the t(14;18) translocation. Molecular and Cellular Biology. 33: 947-57. PMID 23263985 DOI: 10.1128/Mcb.01436-12 |
0.469 |
|
2012 |
Tsai AG, Chen DM, Lin M, Hsieh JC, Okitsu CY, Taghva A, Shibata D, Hsieh CL. Heterogeneity and randomness of DNA methylation patterns in human embryonic stem cells. Dna and Cell Biology. 31: 893-907. PMID 22277069 DOI: 10.1089/Dna.2011.1477 |
0.456 |
|
2011 |
Irvine RA, Okitsu C, Hsieh CL. Q-PCR in combination with ChIP assays to detect changes in chromatin acetylation. Methods in Molecular Biology (Clifton, N.J.). 791: 213-23. PMID 21913082 DOI: 10.1007/978-1-61779-316-5_16 |
0.382 |
|
2010 |
Okitsu CY, Hsieh JC, Hsieh CL. Transcriptional activity affects the H3K4me3 level and distribution in the coding region. Molecular and Cellular Biology. 30: 2933-46. PMID 20404096 DOI: 10.1128/Mcb.01478-09 |
0.411 |
|
2010 |
Roy D, Zhang Z, Lu Z, Hsieh CL, Lieber MR. Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site. Molecular and Cellular Biology. 30: 146-59. PMID 19841062 DOI: 10.1128/Mcb.00897-09 |
0.313 |
|
2008 |
Tsai AG, Lu H, Raghavan SC, Muschen M, Hsieh CL, Lieber MR. Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell. 135: 1130-42. PMID 19070581 DOI: 10.1016/J.Cell.2008.10.035 |
0.422 |
|
2007 |
Okitsu CY, Hsieh CL. DNA methylation dictates histone H3K4 methylation. Molecular and Cellular Biology. 27: 2746-57. PMID 17242185 DOI: 10.1128/Mcb.02291-06 |
0.454 |
|
2006 |
Raghavan SC, Tsai A, Hsieh CL, Lieber MR. Analysis of non-B DNA structure at chromosomal sites in the mammalian genome. Methods in Enzymology. 409: 301-16. PMID 16793408 DOI: 10.1016/S0076-6879(05)09017-8 |
0.476 |
|
2006 |
Higashimoto T, Panopoulos A, Hsieh CL, Zandi E. TNFalpha induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways. Cytokine. 34: 39-50. PMID 16723255 DOI: 10.1016/J.Cyto.2006.03.015 |
0.356 |
|
2006 |
Goll MG, Kirpekar F, Maggert KA, Yoder JA, Hsieh CL, Zhang X, Golic KG, Jacobsen SE, Bestor TH. Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science (New York, N.Y.). 311: 395-8. PMID 16424344 DOI: 10.1126/Science.1120976 |
0.349 |
|
2005 |
Raghavan SC, Hsieh CL, Lieber MR. Both V(D)J coding ends but neither signal end can recombine at the bcl-2 major breakpoint region, and the rejoining is ligase IV dependent. Molecular and Cellular Biology. 25: 6475-84. PMID 16024785 DOI: 10.1128/Mcb.25.15.6475-6484.2005 |
0.452 |
|
2005 |
Raghavan SC, Chastain P, Lee JS, Hegde BG, Houston S, Langen R, Hsieh CL, Haworth IS, Lieber MR. Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation. The Journal of Biological Chemistry. 280: 22749-60. PMID 15840562 DOI: 10.1074/Jbc.M502952200 |
0.421 |
|
2005 |
Hsieh CL. The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1. Bmc Biochemistry. 6: 6. PMID 15799776 DOI: 10.1186/1471-2091-6-6 |
0.436 |
|
2004 |
Ma Y, Lu H, Tippin B, Goodman MF, Shimazaki N, Koiwai O, Hsieh CL, Schwarz K, Lieber MR. A biochemically defined system for mammalian nonhomologous DNA end joining. Molecular Cell. 16: 701-13. PMID 15574326 DOI: 10.1016/J.Molcel.2004.11.017 |
0.424 |
|
2004 |
Raghavan SC, Swanson PC, Wu X, Hsieh CL, Lieber MR. A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex. Nature. 428: 88-93. PMID 14999286 DOI: 10.1038/Nature02355 |
0.396 |
|
2003 |
Hsieh CL, Jones PA. Meddling with methylation. Nature Cell Biology. 5: 502-4. PMID 12776125 DOI: 10.1038/Ncb0603-502 |
0.396 |
|
2003 |
Karanjawala ZE, Hsieh CL, Lieber MR. Overexpression of Cu/Zn superoxide dismutase is lethal for mice lacking double-strand break repair. Dna Repair. 2: 285-94. PMID 12547391 DOI: 10.1016/S1568-7864(02)00218-5 |
0.409 |
|
2002 |
Karanjawala ZE, Adachi N, Irvine RA, Oh EK, Shibata D, Schwarz K, Hsieh CL, Lieber MR. The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants. Dna Repair. 1: 1017-26. PMID 12531011 DOI: 10.1016/S1568-7864(02)00151-9 |
0.405 |
|
2002 |
Chedin F, Lieber MR, Hsieh CL. The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. Proceedings of the National Academy of Sciences of the United States of America. 99: 16916-21. PMID 12481029 DOI: 10.1073/Pnas.262443999 |
0.42 |
|
2002 |
Irvine RA, Lin IG, Hsieh CL. DNA methylation has a local effect on transcription and histone acetylation. Molecular and Cellular Biology. 22: 6689-96. PMID 12215526 DOI: 10.1128/Mcb.22.19.6689-6696.2002 |
0.443 |
|
2002 |
Karanjawala ZE, Murphy N, Hinton DR, Hsieh CL, Lieber MR. Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Current Biology : Cb. 12: 397-402. PMID 11882291 DOI: 10.1016/S0960-9822(02)00684-X |
0.305 |
|
2002 |
Lin IG, Han L, Taghva A, O'Brien LE, Hsieh CL. Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro. Molecular and Cellular Biology. 22: 704-23. PMID 11784849 DOI: 10.1128/Mcb.22.3.704-723.2002 |
0.48 |
|
2001 |
Han L, Lin IG, Hsieh C. Protein binding protects sites on stable episomes and in the chromosome from de novo methylation. Molecular and Cellular Biology. 21: 3416-3424. PMID 11313467 DOI: 10.1128/Mcb.21.10.3416-3424.2001 |
0.419 |
|
2001 |
Lin IG, Hsieh C. Chromosomal DNA demethylation specified by protein binding. Embo Reports. 2: 108-112. PMID 11258701 DOI: 10.1093/Embo-Reports/Kve023 |
0.418 |
|
2000 |
Karanjawala ZE, Shi X, Hsieh C, Lieber MR. The mammalian FEN-1 locus: structure and conserved sequence features. Microbial & Comparative Genomics. 5: 173-177. PMID 11252354 DOI: 10.1089/Omi.1.2000.5.173 |
0.433 |
|
2000 |
Hsieh C. Dynamics of DNA methylation pattern. Current Opinion in Genetics & Development. 10: 224-228. PMID 10753782 DOI: 10.1016/S0959-437X(00)00064-2 |
0.444 |
|
2000 |
Lin IG, Tomzynski TJ, Ou Q, Hsieh C. Modulation of DNA binding protein affinity directly affects target site demethylation. Molecular and Cellular Biology. 20: 2343-2349. PMID 10713158 DOI: 10.1128/Mcb.20.7.2343-2349.2000 |
0.408 |
|
2000 |
Xu GL, Bestor TH, Bourc'his D, Hsieh CL, Tommerup N, Bugge M, Hulten M, Qu X, Russo JJ, Viegas-Péquignot E. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature. 402: 187-91. PMID 10647011 DOI: 10.1038/46052 |
0.452 |
|
1999 |
Karanjawala ZE, Grawunder U, Hsieh C, Lieber MR. The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts Current Biology. 9: 1501-1506. PMID 10607596 DOI: 10.1016/S0960-9822(00)80123-2 |
0.436 |
|
1999 |
Hsieh C. In Vivo Activity of Murine De Novo Methyltransferases, Dnmt3a and Dnmt3b Molecular and Cellular Biology. 19: 8211-8218. PMID 10567546 DOI: 10.1128/Mcb.19.12.8211 |
0.444 |
|
1999 |
Hsieh C. Evidence that protein binding specifies sites of DNA demethylation. Molecular and Cellular Biology. 19: 46-56. PMID 9858530 DOI: 10.1128/Mcb.19.1.46 |
0.512 |
|
1998 |
Graubert TA, Hug BA, Wesselschmidt R, Hsieh CL, Ryan TM, Townes TM, Ley TJ. Stochastic, stage-specific mechanisms account for the variegation of a human globin transgene Nucleic Acids Research. 26: 2849-2858. PMID 9611227 DOI: 10.1093/Nar/26.12.2849 |
0.303 |
|
1998 |
Gauss GH, Domain I, Hsieh C, Lieber MR. V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability. European Journal of Immunology. 28: 351-358. PMID 9485214 DOI: 10.1002/(SICI)1521-4141(199801)28:01<351::AID-IMMU351>3.0.CO;2-# |
0.381 |
|
1997 |
Hsieh CL. Stability of patch methylation and its impact in regions of transcriptional initiation and elongation. Molecular and Cellular Biology. 17: 5897-904. PMID 9315647 DOI: 10.1128/MCB.17.10.5897 |
0.306 |
|
1996 |
Wu X, Li J, Li X, Hsieh CL, Burgers PM, Lieber MR. Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA. Nucleic Acids Research. 24: 2036-43. PMID 8668533 DOI: 10.1093/Nar/24.11.2036 |
0.44 |
|
1995 |
Hiraoka LR, Hsu L, Hsieh C. Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13 Genomics. 25: 323-325. PMID 7774944 DOI: 10.1016/0888-7543(95)80150-K |
0.326 |
|
1995 |
Hiraoka LR, Harrington JJ, Gerhard DS, Lieber MR, Hsieh C. Sequence of human FEN-1, a structure-specific endonuclease, and chromosomal localization of the gene (FEN1) in mouse and human. Genomics. 25: 220-225. PMID 7774922 DOI: 10.1016/0888-7543(95)80129-A |
0.472 |
|
1994 |
Hsu LC, Chang W, Hiraoka L, Hsieh C. Molecular Cloning, Genomic Organization, and Chromosomal Localization of an Additional Human Aldehyde Dehydrogenase Gene, ALDH6 Genomics. 24: 333-341. PMID 7698756 DOI: 10.1006/Geno.1994.1624 |
0.344 |
|
1994 |
Hsieh CL. Dependence of transcriptional repression on CpG methylation density Molecular and Cellular Biology. 14: 5487-5494. PMID 7518564 DOI: 10.1128/Mcb.14.8.5487 |
0.372 |
|
1993 |
Hsieh CL, Gauss G, Lieber MR. Replication, transcription, CpG methylation and DNA topology in V(D)J recombination. Current Topics in Microbiology and Immunology. 182: 125-35. PMID 1490346 DOI: 10.1007/978-3-642-77633-5_15 |
0.337 |
|
1992 |
Harrington J, Hsieh C, Gerton J, Bosma G, Lieber MR. Analysis of the defect in DNA end joining in the murine scid mutation. Molecular and Cellular Biology. 12: 4758-4768. PMID 1406659 DOI: 10.1128/Mcb.12.10.4758 |
0.412 |
|
1992 |
Milatovich A, Hsieh CL, Bonaminio G, Tecott L, Julius D, Francke U. Serotonin receptor 1c gene assigned to X chromosome in human (band q24) and mouse (bands D-F4). Human Molecular Genetics. 1: 681-4. PMID 1302605 DOI: 10.1093/Hmg/1.9.681 |
0.323 |
|
1992 |
Hsieh C, Lieber MR. CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication. The Embo Journal. 11: 315-325. DOI: 10.1002/J.1460-2075.1992.Tb05054.X |
0.426 |
|
1991 |
Hsieh C, Mccloskey RP, Radany E, Lieber MR. V(D)J recombination: evidence that a replicative mechanism is not required. Molecular and Cellular Biology. 11: 3972-3977. PMID 2072902 DOI: 10.1128/Mcb.11.8.3972 |
0.425 |
|
1991 |
Hoegen Iv, Hsieh C, Scharting R, Francke U, Parnes JR. Identity of human Lyb-2 and CD72 and localization of the gene to chromosome 9. European Journal of Immunology. 21: 1425-1431. PMID 2044654 DOI: 10.1002/Eji.1830210615 |
0.339 |
|
1991 |
Hsieh C, Kumar NM, Gilula NB, Francke U. Distribution of genes for gap junction membrane channel proteins on human and mouse chromosomes. Somatic Cell and Molecular Genetics. 17: 191-200. PMID 1849321 DOI: 10.1007/Bf01232976 |
0.403 |
|
1991 |
Lomax MI, Hsieh CL, Darras BT, Francke U. Structure of the human cytochrome c oxidase subunit Vb gene and chromosomal mapping of the coding gene and of seven pseudogenes Genomics. 10: 1-9. PMID 1646156 DOI: 10.1016/0888-7543(91)90476-U |
0.323 |
|
1990 |
Hsieh CL, Sturm R, Herr W, Francke U. The gene for the ubiquitous octamer-binding protein Oct-1 is on human chromosome 1, region cen-q32, and near Ly-22 and Ltw-4 on mouse chromosome 1. Genomics. 6: 666-72. PMID 2341156 DOI: 10.1016/0888-7543(90)90502-L |
0.317 |
|
1990 |
Affholter JA, Hsieh C, Francke U, Roth RA. Insulin-degrading enzyme: stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes. Molecular Endocrinology. 4: 1125-1135. PMID 2293021 DOI: 10.1210/Mend-4-8-1125 |
0.345 |
|
1990 |
Kuo CJ, Conley PB, Hsieh CL, Francke U, Crabtree GR. Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1. Proceedings of the National Academy of Sciences of the United States of America. 87: 9838-42. PMID 2263635 DOI: 10.1073/Pnas.87.24.9838 |
0.312 |
|
1990 |
Seharaseyon J, Bober E, Hsieh C, Fodor WL, Francke U, Arnold H, Vanin EF. Human embryonic/atrial myosin alkali light chain gene: characterization, sequence, and chromosomal location. Genomics. 7: 289-293. PMID 2129532 DOI: 10.1016/0888-7543(90)90554-8 |
0.312 |
|
1990 |
Gerstein RM, Frankel WN, Hsieh CL, Durdik JM, Rath S, Coffin JM, Nisonoff A, Selsing E. Isotype switching of an immunoglobulin heavy chain transgene occurs by DNA recombination between different chromosomes. Cell. 63: 537-48. PMID 2121365 DOI: 10.1016/0092-8674(90)90450-S |
0.371 |
|
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