Ayyappan K. Rajasekaran - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Cell Biology, Molecular Biology

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 David JM, Rajasekaran AK. Gramicidin A: A New Mission for an Old Antibiotic. Journal of Kidney Cancer and Vhl. 2: 15-24. PMID 28326255 DOI: 10.15586/jkcvhl.2015.21  0.44
2015 Patil PU, D'Ambrosio J, Inge LJ, Mason RW, Rajasekaran AK. Carcinoma cells induce lumen filling and EMT in epithelial cells through soluble E-cadherin-mediated activation of EGFR. Journal of Cell Science. 128: 4366-79. PMID 26483386 DOI: 10.1242/jcs.173518  0.44
2015 Krishnan V, Xu X, Kelly D, Snook A, Waldman SA, Mason RW, Jia X, Rajasekaran AK. CD19-Targeted Nanodelivery of Doxorubicin Enhances Therapeutic Efficacy in B-Cell Acute Lymphoblastic Leukemia. Molecular Pharmaceutics. 12: 2101-11. PMID 25898125 DOI: 10.1021/acs.molpharmaceut.5b00071  0.44
2015 Huynh TP, Barwe SP, Lee SJ, McSpadden R, Franco OE, Hayward SW, Damoiseaux R, Grubbs SS, Petrelli NJ, Rajasekaran AK. Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression. Plos One. 10: e0122442. PMID 25836370 DOI: 10.1371/journal.pone.0122442  0.44
2014 Sampson VB, David JM, Puig I, Patil PU, de Herreros AG, Thomas GV, Rajasekaran AK. Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinoma. Plos One. 9: e102041. PMID 25025131 DOI: 10.1371/journal.pone.0102041  0.44
2014 David JM, Owens TA, Inge LJ, Bremner RM, Rajasekaran AK. Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinoma. Molecular Cancer Therapeutics. 13: 788-99. PMID 24493697 DOI: 10.1158/1535-7163.MCT-13-0891  0.44
2014 Selvakumar P, Owens TA, David JM, Petrelli NJ, Christensen BC, Lakshmikuttyamma A, Rajasekaran AK. Epigenetic silencing of Na,K-ATPase β 1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma. Epigenetics. 9: 579-86. PMID 24452105 DOI: 10.4161/epi.27795  0.44
2014 Krishnan V, Rajasekaran AK. Clinical nanomedicine: a solution to the chemotherapy conundrum in pediatric leukemia therapy. Clinical Pharmacology and Therapeutics. 95: 168-78. PMID 24013811 DOI: 10.1038/clpt.2013.174  0.44
2013 David JM, Owens TA, Barwe SP, Rajasekaran AK. Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells. Molecular Cancer Therapeutics. 12: 2296-307. PMID 24006494 DOI: 10.1158/1535-7163.MCT-13-0445  0.44
2013 Krishnan V, Xu X, Barwe SP, Yang X, Czymmek K, Waldman SA, Mason RW, Jia X, Rajasekaran AK. Dexamethasone-loaded block copolymer nanoparticles induce leukemia cell death and enhance therapeutic efficacy: a novel application in pediatric nanomedicine. Molecular Pharmaceutics. 10: 2199-210. PMID 23194373 DOI: 10.1021/mp300350e  0.44
2012 Barwe SP, Skay A, McSpadden R, Huynh TP, Langhans SA, Inge LJ, Rajasekaran AK. Na,K-ATPase β-subunit cis homo-oligomerization is necessary for epithelial lumen formation in mammalian cells. Journal of Cell Science. 125: 5711-20. PMID 23077177 DOI: 10.1242/jcs.108795  0.44
2012 David JM, Rajasekaran AK. Dishonorable discharge: the oncogenic roles of cleaved E-cadherin fragments. Cancer Research. 72: 2917-23. PMID 22659456 DOI: 10.1158/0008-5472.CAN-11-3498  0.44
2012 Huynh TP, Mah V, Sampson VB, Chia D, Fishbein MC, Horvath S, Alavi M, Wu DC, Harper J, Sarafian T, Dubinett SM, Langhans SA, Goodglick L, Rajasekaran AK. Na,K-ATPase is a target of cigarette smoke and reduced expression predicts poor patient outcome of smokers with lung cancer. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L1150-8. PMID 22345575 DOI: 10.1152/ajplung.00384.2010  0.44
2011 Presson AP, Yoon NK, Bagryanova L, Mah V, Alavi M, Maresh EL, Rajasekaran AK, Goodglick L, Chia D, Horvath S. Protein expression based multimarker analysis of breast cancer samples. Bmc Cancer. 11: 230. PMID 21651811 DOI: 10.1186/1471-2407-11-230  0.44
2011 Inge LJ, Barwe SP, D'Ambrosio J, Gopal J, Lu K, Ryazantsev S, Rajasekaran SA, Rajasekaran AK. Soluble E-cadherin promotes cell survival by activating epidermal growth factor receptor. Experimental Cell Research. 317: 838-48. PMID 21211535 DOI: 10.1016/j.yexcr.2010.12.025  0.44
2010 Rajasekaran SA, Huynh TP, Wolle DG, Espineda CE, Inge LJ, Skay A, Lassman C, Nicholas SB, Harper JF, Reeves AE, Ahmed MM, Leatherman JM, Mullin JM, Rajasekaran AK. Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis. Molecular Cancer Therapeutics. 9: 1515-24. PMID 20501797 DOI: 10.1158/1535-7163.MCT-09-0832  0.44
2009 Barwe SP, Jordan MC, Skay A, Inge L, Rajasekaran SA, Wolle D, Johnson CL, Neco P, Fang K, Rozengurt N, Goldhaber JI, Roos KP, Rajasekaran AK. Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit. Journal of Molecular and Cellular Cardiology. 47: 552-60. PMID 19683723 DOI: 10.1016/j.yjmcc.2009.07.018  0.44
2009 Tummala R, Wolle D, Barwe SP, Sampson VB, Rajasekaran AK, Pendyala L. Expression of Na,K-ATPase-beta(1) subunit increases uptake and sensitizes carcinoma cells to oxaliplatin. Cancer Chemotherapy and Pharmacology. 64: 1187-94. PMID 19322565 DOI: 10.1007/s00280-009-0985-x  0.4
2009 Rajasekaran SA, Rajasekaran AK. Na,K-ATPase and epithelial tight junctions. Frontiers in Bioscience (Landmark Edition). 14: 2130-48. PMID 19273189 DOI: 10.2741/3367  0.44
2008 Rajasekaran SA, Christiansen JJ, Schmid I, Oshima E, Ryazantsev S, Sakamoto K, Weinstein J, Rao NP, Rajasekaran AK. Prostate-specific membrane antigen associates with anaphase-promoting complex and induces chromosomal instability. Molecular Cancer Therapeutics. 7: 2142-51. PMID 18645024 DOI: 10.1158/1535-7163.MCT-08-0005  0.44
2008 Inge LJ, Rajasekaran SA, Wolle D, Barwe SP, Ryazantsev S, Ewing CM, Isaacs WB, Rajasekaran AK. alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling. Molecular Cancer Therapeutics. 7: 1386-97. PMID 18566211 DOI: 10.1158/1535-7163.MCT-07-2029  0.44
2008 Inge LJ, Rajasekaran SA, Yoshimoto K, Mischel PS, McBride W, Landaw E, Rajasekaran AK. Evidence for a potential tumor suppressor role for the Na,K-ATPase beta1-subunit. Histology and Histopathology. 23: 459-67. PMID 18228203  0.44
2008 Rajasekaran SA, Beyenbach KW, Rajasekaran AK. Interactions of tight junctions with membrane channels and transporters. Biochimica Et Biophysica Acta. 1778: 757-69. PMID 18086552 DOI: 10.1016/j.bbamem.2007.11.007  0.44
2008 Seligson DB, Rajasekaran SA, Yu H, Liu X, Eeva M, Tze S, Ball W, Horvath S, deKernion JB, Rajasekaran AK. Na,K-adenosine triphosphatase alpha1-subunit predicts survival of renal clear cell carcinoma. The Journal of Urology. 179: 338-45. PMID 18006011 DOI: 10.1016/j.juro.2007.08.094  0.44
2007 Olson WC, Heston WDW, Rajasekaran AK. Clinical trials of cancer therapies targeting prostate-specific membrane antigen Reviews On Recent Clinical Trials. 2: 182-190. PMID 18474004 DOI: 10.2174/157488707781662724  0.44
2007 Goodman OB, Barwe SP, Ritter B, McPherson PS, Vasko AJ, Keen JH, Nanus DM, Bander NH, Rajasekaran AK. Interaction of prostate specific membrane antigen with clathrin and the adaptor protein complex-2. International Journal of Oncology. 31: 1199-203. PMID 17912448  0.4
2007 Barwe SP, Maul RS, Christiansen JJ, Anilkumar G, Cooper CR, Kohn DB, Rajasekaran AK. Preferential association of prostate cancer cells expressing prostate specific membrane antigen to bone marrow matrix. International Journal of Oncology. 30: 899-904. PMID 17332929  0.44
2007 Barwe SP, Kim S, Rajasekaran SA, Bowie JU, Rajasekaran AK. Janus Model of The Na,K-ATPase β-Subunit Transmembrane Domain: Distinct Faces Mediate α/β Assembly and β-β Homo-oligomerization Journal of Molecular Biology. 365: 706-714. PMID 17078968 DOI: 10.1016/j.jmb.2006.10.029  0.44
2007 Rajasekaran SA, Barwe SP, Gopal J, Ryazantsev S, Schneeberger EE, Rajasekaran AK. Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G124-33. PMID 16959951 DOI: 10.1152/ajpgi.00297.2006  0.44
2006 Christiansen JJ, Weimbs T, Bander N, Rajasekaran AK. Differing effects of microtubule depolymerizing and stabilizing chemotherapeutic agents on t-SNARE-mediated apical targeting of prostate-specific membrane antigen. Molecular Cancer Therapeutics. 5: 2468-73. PMID 17041090 DOI: 10.1158/1535-7163.MCT-06-0253  0.44
2006 Christiansen JJ, Rajasekaran AK. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Research. 66: 8319-26. PMID 16951136 DOI: 10.1158/0008-5472.CAN-06-0410  0.92
2006 Anilkumar G, Barwe SP, Christiansen JJ, Rajasekaran SA, Kohn DB, Rajasekaran AK. Association of prostate-specific membrane antigen with caveolin-1 and its caveolae-dependent internalization in microvascular endothelial cells: implications for targeting to tumor vasculature. Microvascular Research. 72: 54-61. PMID 16713605 DOI: 10.1016/j.mvr.2006.03.004  0.44
2006 Liu W, Konduri SD, Bansal S, Nayak BK, Rajasekaran SA, Karuppayil SM, Rajasekaran AK, Das GM. Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its function. The Journal of Biological Chemistry. 281: 9837-40. PMID 16469747 DOI: 10.1074/jbc.C600001200  0.44
2005 Rajasekaran SA, Barwe SP, Rajasekaran AK. Multiple functions of Na,K-ATPase in epithelial cells. Seminars in Nephrology. 25: 328-34. PMID 16139688 DOI: 10.1016/j.semnephrol.2005.03.008  0.44
2005 Christiansen JJ, Rajasekaran SA, Inge L, Cheng L, Anilkumar G, Bander NH, Rajasekaran AK. N-glycosylation and microtubule integrity are involved in apical targeting of prostate-specific membrane antigen: implications for immunotherapy. Molecular Cancer Therapeutics. 4: 704-14. PMID 15897234 DOI: 10.1158/1535-7163.MCT-04-0171  0.44
2005 Rajasekaran AK, Anilkumar G, Christiansen JJ. Is prostate-specific membrane antigen a multifunctional protein? American Journal of Physiology. Cell Physiology. 288: C975-81. PMID 15840561 DOI: 10.1152/ajpcell.00506.2004  0.92
2005 Barwe SP, Anilkumar G, Moon SY, Zheng Y, Whitelegge JP, Rajasekaran SA, Rajasekaran AK. Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility. Molecular Biology of the Cell. 16: 1082-94. PMID 15616195 DOI: 10.1091/mbc.E04-05-0427  0.44
2005 Kim G, Rajasekaran SA, Thomas G, Rosen EA, Landaw EM, Shintaku P, Lassman C, Said J, Rajasekaran AK. Renal clear-cell carcinoma: an ultrastructural study on the junctional complexes. Histology and Histopathology. 20: 35-44. PMID 15578420  0.44
2004 Rajasekaran SA, Gopal J, Espineda C, Ryazantsev S, Schneeberger EE, Rajasekaran AK. HPAF-II, a cell culture model to study pancreatic epithelial cell structure and function. Pancreas. 29: e77-83. PMID 15367897  0.44
2004 Rajasekaran SA, Gopal J, Willis D, Espineda C, Twiss JL, Rajasekaran AK. Na,K-ATPase beta1-subunit increases the translation efficiency of the alpha1-subunit in MSV-MDCK cells. Molecular Biology of the Cell. 15: 3224-32. PMID 15133131 DOI: 10.1091/mbc.E04-03-0222  0.44
2004 Espineda CE, Chang JH, Twiss J, Rajasekaran SA, Rajasekaran AK. Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma. Molecular Biology of the Cell. 15: 1364-73. PMID 14699059 DOI: 10.1091/mbc.E03-09-0646  0.44
2004 Lu KV, Jong KA, Rajasekaran AK, Cloughesy TF, Mischel PS. Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 8-20. PMID 14631378 DOI: 10.1038/sj.labinvest.3700003  0.44
2003 Rajasekaran SA, Anilkumar G, Oshima E, Bowie JU, Liu H, Heston W, Bander NH, Rajasekaran AK. A Novel Cytoplasmic Tail MXXXL Motif Mediates the Internalization of Prostate-specific Membrane Antigen Molecular Biology of the Cell. 14: 4835-4845. PMID 14528023 DOI: 10.1091/mbc.E02-11-0731  0.44
2003 Rajasekaran AK, Rajasekaran SA. Role of Na-K-ATPase in the assembly of tight junctions. American Journal of Physiology. Renal Physiology. 285: F388-96. PMID 12890662 DOI: 10.1152/ajprenal.00439.2002  0.44
2003 Rajasekaran SA, Gopal J, Rajasekaran AK. Expression of Na,K-ATPase beta-subunit in transformed MDCK cells increases the translation of the Na,K-ATPase alpha-subunit. Annals of the New York Academy of Sciences. 986: 652-4. PMID 12763913 DOI: 10.1111/j.1749-6632.2003.tb07277.x  0.44
2003 Rajasekaran AK, Gopal J, Rajasekaran SA. Na,K-ATPase in the regulation of epithelial cell structure. Annals of the New York Academy of Sciences. 986: 649-51. PMID 12763912  0.44
2003 Anilkumar G, Rajasekaran SA, Wang S, Hankinson O, Bander NH, Rajasekaran AK. Prostate-specific membrane antigen association with filamin A modulates its internalization and NAALADase activity. Cancer Research. 63: 2645-8. PMID 12750292  0.44
2003 Espineda C, Seligson DB, James Ball W, Rao J, Palotie A, Horvath S, Huang Y, Shi T, Rajasekaran AK. Analysis of the Na,K-ATPase alpha- and beta-subunit expression profiles of bladder cancer using tissue microarrays. Cancer. 97: 1859-68. PMID 12673711 DOI: 10.1002/cncr.11267  0.44
2003 Christiansen JJ, Rajasekaran SA, Moy P, Butch A, Goodglick L, Gu Z, Reiter RE, Bander NH, Rajasekaran AK. Polarity of prostate specific membrane antigen, prostate stem cell antigen, and prostate specific antigen in prostate tissue and in a cultured epithelial cell line. The Prostate. 55: 9-19. PMID 12640656 DOI: 10.1002/pros.10203  0.44
2003 Rajasekaran SA, Hu J, Gopal J, Gallemore R, Ryazantsev S, Bok D, Rajasekaran AK. Na,K-ATPase inhibition alters tight junction structure and permeability in human retinal pigment epithelial cells. American Journal of Physiology. Cell Physiology. 284: C1497-507. PMID 12570983 DOI: 10.1152/ajpcell.00355.2002  0.44
2001 Rajasekaran SA, Palmer LG, Moon SY, Peralta Soler A, Apodaca GL, Harper JF, Zheng Y, Rajasekaran AK. Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells. Molecular Biology of the Cell. 12: 3717-32. PMID 11739775 DOI: 10.1091/mbc.12.12.3717  0.44
2001 Zheng JQ, Kelly TK, Chang B, Ryazantsev S, Rajasekaran AK, Martin KC, Twiss JL. A functional role for intra-axonal protein synthesis during axonal regeneration from adult sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9291-303. PMID 11717363  0.44
2001 Rajasekaran SA, Palmer LG, Quan K, Harper JF, Ball WJ, Bander NH, Peralta Soler A, Rajasekaran AK. Na,K-ATPase beta-subunit is required for epithelial polarization, suppression of invasion, and cell motility. Molecular Biology of the Cell. 12: 279-95. PMID 11179415  0.44
1999 Rajasekaran SA, Ball WJ, Bander NH, Liu H, Pardee JD, Rajasekaran AK. Reduced expression of beta-subunit of Na,K-ATPase in human clear-cell renal cell carcinoma. The Journal of Urology. 162: 574-80. PMID 10411090 DOI: 10.1016/S0022-5347(05)68629-6  0.44
1996 Rajasekaran AK, Hojo M, Huima T, Rodriguez-Boulan E. Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions. The Journal of Cell Biology. 132: 451-63. PMID 8636221 DOI: 10.1083/jcb.132.3.451  0.44
1995 Rajasekaran AK, Zhou Z, Prakash K, Das G, Kreibich G. Functional characterization of the cis-regulatory elements of the rat ribophorin I gene. Nucleic Acids Research. 23: 313-9. PMID 7885824 DOI: 10.1093/nar/23.3.313  0.44
1995 Rajasekaran AK, Langhans-Rajasekaran SA, Gould RM, Rodriguez-Boulan E, Morimoto T. A simple biochemical approach to quantitate rough endoplasmic reticulum. The American Journal of Physiology. 268: C308-16. PMID 7864069  0.44
1994 Rajasekaran AK, Humphrey JS, Wagner M, Miesenböck G, Le Bivic A, Bonifacino JS, Rodriguez-Boulan E. TGN38 recycles basolaterally in polarized Madin-Darby canine kidney cells. Molecular Biology of the Cell. 5: 1093-103. PMID 7865877  0.44
1991 Sen I, Rajasekaran AK. Angiotensin II-binding protein in adult and neonatal rat heart Journal of Molecular and Cellular Cardiology. 23: 563-572. PMID 1886136 DOI: 10.1016/0022-2828(91)90048-Q  0.44
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