Kathleen M. Sakamoto, Ph.D. - Publications

Affiliations: 
2004 California Institute of Technology, Pasadena, CA 
Area:
Ubiquitin-Dependent Proteolysis and Cell Division

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez C, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, ... Sakamoto KM, et al. Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a. Experimental Hematology. PMID 32926965 DOI: 10.1016/J.Exphem.2020.09.187  0.313
2020 Chae HD, Dutta R, Tiu B, Hoff FW, Accordi B, Serafin V, Youn M, Huang M, Sumarsono N, Davis KL, Lacayo NJ, Pigazzi M, Horton TM, Kornblau SM, Sakamoto KM. RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit. Oncotarget. 11: 2387-2403. PMID 32637030 DOI: 10.18632/Oncotarget.27630  0.384
2020 Wilkes MC, Siva K, Chen J, Varetti G, Youn MY, Chae H, Ek F, Olsson R, Lundbäck T, Dever DP, Nishimura T, Narla A, Glader B, Nakauchi H, Porteus MH, ... ... Sakamoto KM, et al. Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase. Nature Communications. 11: 3344. PMID 32620751 DOI: 10.1038/S41467-020-17100-Z  0.382
2020 Wojcicki AV, Kasowski MM, Sakamoto KM, Lacayo N. Metabolomics in acute myeloid leukemia. Molecular Genetics and Metabolism. PMID 32457018 DOI: 10.1016/J.Ymgme.2020.05.005  0.314
2020 Huang M, Zeki J, Sumarsono N, Coles GL, Taylor JS, Danzer E, Bruzoni M, Hazard FK, Lacayo NJ, Sakamoto KM, Dunn JCY, Spunt SL, Chiu B. EPIGENETIC TARGETING OF TERT-ASSOCIATED GENE EXPRESSION SIGNATURE IN HUMAN NEUROBLASTOMA WITH TERT OVEREXPRESSION. Cancer Research. PMID 31900258 DOI: 10.1158/0008-5472.Can-19-2560  0.387
2019 Youn M, Huang H, Chen C, Kam S, Wilkes MC, Chae HD, Sridhar KJ, Greenberg PL, Glader B, Narla A, Lin S, Sakamoto KM. MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways. Blood Advances. 3: 2751-2763. PMID 31540902 DOI: 10.1182/Bloodadvances.2019000537  0.309
2019 Chae HD, Cox N, Capolicchio S, Lee JW, Horikoshi N, Kam S, Ng AA, Edwards J, Butler TL, Chan J, Lee Y, Potter G, Capece MC, Liu CW, Wakatsuki S, ... ... Sakamoto KM, et al. SAR optimization studies on modified salicylamides as a potential treatment for acute myeloid leukemia through inhibition of the CREB pathway. Bioorganic & Medicinal Chemistry Letters. PMID 31253529 DOI: 10.1016/J.Bmcl.2019.06.023  0.357
2019 Wilkes MC, Mercado JD, Saxena M, Chen J, Siva K, Chae H, Youn M, Wentworth EP, Jung K, Sathianathen R, Patel H, Glader B, Narla A, Repellin CE, Gazda HT, ... ... Sakamoto KM, et al. Pharmacological Inhibition of Nemo-like Kinase Rescues mTOR-Mediated Translation and Primes Progenitors for Leucine-Stimulated Erythroid Expansion in Pre-Clinical Models of Diamond Blackfan Anemia Blood. 134: 455-455. DOI: 10.1182/Blood-2019-129570  0.421
2019 Wilkes M, Mercado J, Saxena M, Chen J, Siva K, Varetti G, Chae H, Youn M, Gazda H, Serrano M, Flygare J, Sakamoto K. 3182 – PHARMACOLOGICAL INHIBITION OF NEMO-LIKE KINASE RESCUES MTOR-MEDIATED TRANSLATION AND ERYTHROPOIESIS IN PRE-CLINICAL MODELS OF DIAMOND BLACKFAN ANEMIA Experimental Hematology. 76: e5-e6. DOI: 10.1016/J.Exphem.2019.09.019  0.374
2018 Duque-Afonso J, Lin CH, Han K, Morgens DW, Jeng EE, Weng Z, Jeong J, Wong SHK, Zhu L, Wei MC, Chae HD, Schrappe M, Cario G, Duyster J, Sakamoto KM, et al. CBP modulates sensitivity to dasatinib in pre-BCR+ acute lymphoblastic leukemia. Cancer Research. PMID 30262461 DOI: 10.1158/0008-5472.Can-18-1703  0.346
2018 Danilova N, Wilkes M, Bibikova E, Youn MY, Sakamoto KM, Lin S. Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. Scientific Reports. 8: 5165. PMID 29581525 DOI: 10.1038/S41598-018-23561-6  0.352
2018 Chae HD, Cox N, Dahl GV, Lacayo NJ, Davis KL, Capolicchio S, Smith M, Sakamoto KM. Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways. Oncotarget. 9: 4301-4317. PMID 29435104 DOI: 10.18632/Oncotarget.23794  0.466
2018 Chae H, Murphy LC, Donato M, Lee AG, Sweet-Cordero EA, Abidi P, Bittencourt H, Lacayo NJ, Dahl GVH, Aftandilian C, Davis KL, Huang M, Sumarsono N, Redell M, Fu CH, ... ... Sakamoto KM, et al. Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells Blood. 132: 4246-4246. DOI: 10.1182/Blood-2018-99-119974  0.369
2018 Wilkes MC, Chen J, Siva K, Veretti G, Dever DP, Youn M, Chae H, Mercado JD, Saxena M, Narla A, Glader B, Porteus M, Repellin CE, Gazda HT, Serrano M, ... ... Sakamoto KM, et al. Pharmacological Inhibition of Nlk (Nemo-like Kinase) Rescues Erythropoietic Defects in Pre-Clinical Models of Diamond Blackfan Anemia Blood. 132: 754-754. DOI: 10.1182/Blood-2018-99-119954  0.407
2018 Wilkes MC, Takasaki K, Youn M, Chae H, Narla A, Sakamoto KM. Chromatin Organization By SATB1 Regulates HSP70 Induction in Early Erythropoiesis and Lost in Diamond Blackfan Anemia Blood. 132: 2591-2591. DOI: 10.1182/Blood-2018-99-119729  0.379
2018 Youn M, Huang H, Chen C, Kam S, Wilkes MC, Chae H, Narla A, Lin S, Sakamoto KM. MMP9 Inhibition Rescues the Erythroid Defect in RPS14-Deficient Del(5q) MDS Models Blood. 132: 756-756. DOI: 10.1182/Blood-2018-99-117508  0.337
2018 Aftandilian C, Sakamoto KM, Davis KL, Dahl GVH, Lacayo NJ. Chromatin Remodeling Therapy and Capizzi Methotrexate in Treatment-Related MDS/AML Blood. 132: 5222-5222. DOI: 10.1182/Blood-2018-99-110481  0.312
2017 Wilkes MC, Repellin CE, Sakamoto KM. Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis. Molecular Genetics and Metabolism. PMID 28757239 DOI: 10.1016/J.Ymgme.2017.07.008  0.302
2017 Sakamoto KM. Lost in translation: RP and GATA1 mutations in DBA. Blood. 129: 3048-3049. PMID 28596438 DOI: 10.1182/Blood-2017-04-778969  0.364
2017 Youn M, Wang N, LaVasseur C, Bibikova E, Kam S, Glader B, Sakamoto KM, Narla A. Loss of FOXM1 promotes erythropoiesis through increased proliferation of erythroid progenitors. Haematologica. PMID 28154085 DOI: 10.3324/Haematol.2016.156257  0.438
2017 Wilkes MC, Lee JW, Kudaravalli S, Narla A, Glader B, Sakamoto KM. Nemo-like Kinase Hyper-Activated in Erythroid Progenitors in Models of Diamond Blackfan Anemia Blood. 130: 78-78. DOI: 10.1182/Blood.V130.Suppl_1.78.78  0.422
2016 François S, Sen N, Mitton B, Xiao X, Sakamoto KM, Arvin A. Varicella-Zoster Virus Activates CREB and Inhibition of the pCREB-p300/CBP- Interaction Inhibits Viral Replication in vitro and Skin Pathogenesis in vivo. Journal of Virology. PMID 27440893 DOI: 10.1128/Jvi.00920-16  0.32
2016 Dutta R, Tiu B, Sakamoto KM. CBP/p300 acetyltransferase activity in hematologic malignancies. Molecular Genetics and Metabolism. PMID 27380996 DOI: 10.1016/J.Ymgme.2016.06.013  0.365
2016 Ear J, Hsueh J, Nguyen M, Zhang Q, Sung V, Chopra R, Sakamoto KM, Lin S. A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 27216296 DOI: 10.1016/J.Jgg.2016.03.007  0.325
2016 Mitton B, Chae HD, Hsu K, Dutta R, Aldana-Masangkay G, Ferrari R, Davis K, Tiu BC, Kaul A, Lacayo N, Dahl G, Xie F, Li BX, Breese MR, Landaw EM, ... ... Sakamoto KM, et al. Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. Leukemia. PMID 27211267 DOI: 10.1038/Leu.2016.139  0.477
2016 Huang W, Luan CH, Hjort EE, Bei L, Mishra R, Sakamoto KM, Platanias LC, Eklund EA. The role of Fas-associated phosphatase 1 in leukemia stem cell-persistence during tyrosine kinase inhibitor-treatment of chronic myeloid leukemia. Leukemia. PMID 26984787 DOI: 10.1038/Leu.2016.66  0.364
2016 Mitton B, Hsu K, Dutta R, Tiu BC, Cox N, McLure KG, Chae HD, Smith M, Eklund EA, Solow-Cordero DE, Sakamoto KM. Small molecule screen for inhibitors of expression from canonical CREB response element-containing promoters. Oncotarget. PMID 26840025 DOI: 10.18632/Oncotarget.7085  0.392
2016 Wilkes M, Bibikova E, Youn M, Lee AG, Eskin A, Nelson S, Glader B, Narla A, Sakamoto KM. Role of Mir-34 Upregulation in Disruption of c-Myc, c-Myb and NOTCH Signaling in Diamond-Blackfan Anemia Blood. 128: 3895-3895. DOI: 10.1182/Blood.V128.22.3895.3895  0.34
2016 Dutta R, Castellanos M, Tiu B, Chae H, Davis KL, Sakamoto KM. RSK Inhibition Suppresses AML Proliferation through Activation of DNA Damage Pathways and S Phase Arrest Blood. 128: 2894-2894. DOI: 10.1182/Blood.V128.22.2894.2894  0.45
2016 Chae H, Cox N, Zhang X, Lee JW, Morgens D, Bassik MC, Smith M, Sakamoto KM. The Salicylamide Derivative, Niclosamide, Inhibits CREB Function in Acute Myeloid Leukemia Cells In Vitro and In Vivo Blood. 128: 1647-1647. DOI: 10.1182/Blood.V128.22.1647.1647  0.476
2015 Rankin EB, Narla A, Park JK, Lin S, Sakamoto KM. Biology of the bone marrow microenvironment and myelodysplastic syndromes. Molecular Genetics and Metabolism. PMID 26210353 DOI: 10.1016/J.Ymgme.2015.07.004  0.341
2015 Kim PG, Nakano H, Das PP, Chen MJ, Rowe RG, Chou SS, Ross SJ, Sakamoto KM, Zon LI, Schlaeger TM, Orkin SH, Nakano A, Daley GQ. Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. The Journal of Experimental Medicine. 212: 633-48. PMID 25870201 DOI: 10.1084/Jem.20141514  0.388
2015 Chae HD, Mitton B, Lacayo NJ, Sakamoto KM. Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA. Leukemia. 29: 1379-89. PMID 25541153 DOI: 10.1038/Leu.2014.350  0.426
2015 Sakamoto KM, Grant S, Saleiro D, Crispino JD, Hijiya N, Giles F, Platanias L, Eklund EA. Targeting novel signaling pathways for resistant acute myeloid leukemia. Molecular Genetics and Metabolism. 114: 397-402. PMID 25533111 DOI: 10.1016/J.Ymgme.2014.11.017  0.336
2015 Youn M, Bibikova E, LaVasseur C, Glader B, Sakamoto K, Narla A. Loss of FoxM1 Promotes Erythroid Differentiation through Increased Proliferation of Erythroid Progenitors Blood. 126: 933-933. DOI: 10.1182/Blood.V126.23.933.933  0.412
2015 Dutta R, Tiu B, Kaul A, Mitton B, Sakamoto KM. CREB Increases Chemotherapy Resistance through Regulation of the DNA Damage Repair Pathway in AML Cells Blood. 126: 1390-1390. DOI: 10.1182/Blood.V126.23.1390.1390  0.389
2014 Bibikova E, Youn MY, Danilova N, Ono-Uruga Y, Konto-Ghiorghi Y, Ochoa R, Narla A, Glader B, Lin S, Sakamoto KM. TNF-mediated inflammation represses GATA1 and activates p38 MAP kinase in RPS19-deficient hematopoietic progenitors. Blood. 124: 3791-8. PMID 25270909 DOI: 10.1182/Blood-2014-06-584656  0.351
2014 Danilova N, Bibikova E, Covey TM, Nathanson D, Dimitrova E, Konto Y, Lindgren A, Glader B, Radu CG, Sakamoto KM, Lin S. The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia. Disease Models & Mechanisms. 7: 895-905. PMID 24812435 DOI: 10.1242/Dmm.015495  0.344
2014 Chae H, Mitton B, Sakamoto K. CREB Regulates Cell Cycle Progression through RFC3-PCNA Axis in Acute Myeloid Leukemia Blood. 124: 881-881. DOI: 10.1182/Blood.V124.21.881.881  0.463
2014 Youn M, Bibikova E, Danilova N, Ono-Uruga Y, Konto-Ghiorghi Y, Ochoa R, Narla A, Glader B, Lin S, Sakamoto K. RPS19 Deficiency Leads to GATA1 Downregulation through TNF-Mediated p38 MAPK Activation Blood. 124: 2934-2934. DOI: 10.1182/Blood.V124.21.2934.2934  0.396
2014 Mitton B, Dutta R, Hsu Y, Sakamoto K. The Role of pp90rsk-Mediated CREB Phosphorylation in Acute Myelogenous Leukemia Blood. 124: 2229-2229. DOI: 10.1182/Blood.V124.21.2229.2229  0.449
2014 Mitra SS, Gholamin S, Volkmer J, Feroze A, Liu J, Achrol A, Wang L, Sayles L, Zhang M, Sakamoto K, Monje-Deisseroth M, Cho Y, Sweet-Cordero A, Majeti R, Cheshier S, et al. Abstract PR12: Overcoming immune evasion in pediatric hematologic and solid tumor malignancies: A preclinical study using a humanized anti-CD47 antibody Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-Pr12  0.325
2013 Wen AY, Landaw EM, Ochoa R, Cho M, Chao A, Lawson G, Sakamoto KM. Increased abscess formation and defective chemokine regulation in CREB transgenic mice. Plos One. 8: e55866. PMID 23405224 DOI: 10.1371/Journal.Pone.0055866  0.347
2013 Pigazzi M, Manara E, Bresolin S, Tregnago C, Beghin A, Baron E, Giarin E, Cho EC, Masetti R, Rao DS, Sakamoto KM, Basso G. MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation. Haematologica. 98: 602-10. PMID 23100280 DOI: 10.3324/Haematol.2012.070664  0.359
2013 Mitton B, Dutta R, Hsu Y, Ochoa R, Landaw E, Xiao X, Sakamoto K. The pp90rsk-CREB Signaling Pathway Regulates Apoptosis In Acute Myelogenous Leukemia Blood. 122: 3801-3801. DOI: 10.1182/Blood.V122.21.3801.3801  0.443
2013 Chae H, Sakamoto K. Replication Factor C3 Is a Direct Target Of CREB, Promotes G1/S Transition Of Acute Myeloid Leukemia Cells, and Increases Hematopoietic Stem/Progenitor Cell Self-Renewal Blood. 122: 3754-3754. DOI: 10.1182/Blood.V122.21.3754.3754  0.452
2013 Konto-Ghiorghi Y, Bibikova E, Glader B, Narla A, Sakamoto K. Transcriptional Profiling and Cytokine Signaling In The Pathogenesis Of Diamond-Blackfan Anemia Blood. 122: 2474-2474. DOI: 10.1182/Blood.V122.21.2474.2474  0.358
2013 Danilova N, Elena B, Covey T, Nathanson D, Dimitrova E, Anne L, Glader B, Radu C, Sakamoto K, Lin S. Defective Nucleotide Metabolism Contributes To p53 Activation In Diamond-Blackfan Anemia Blood. 122: 1225-1225. DOI: 10.1182/Blood.V122.21.1225.1225  0.389
2012 Sandoval S, Kraus C, Cho EC, Cho M, Bies J, Manara E, Accordi B, Landaw EM, Wolff L, Pigazzi M, Sakamoto KM. Sox4 cooperates with CREB in myeloid transformation. Blood. 120: 155-65. PMID 22627767 DOI: 10.1182/Blood-2011-05-357418  0.455
2011 Cho EC, Mitton B, Sakamoto KM. CREB and leukemogenesis. Critical Reviews in Oncogenesis. 16: 37-46. PMID 22150306 DOI: 10.1615/Critrevoncog.V16.I1-2.50  0.386
2011 Mitton B, Cho EC, Aldana-Masangkay GI, Sakamoto KM. The function of cyclic-adenosine monophosphate responsive element-binding protein in hematologic malignancies. Leukemia & Lymphoma. 52: 2057-63. PMID 22023600 DOI: 10.3109/10428194.2011.584994  0.428
2011 Sakamoto KM. Editorial: granulopoiesis versus monopoiesis: a consequence of transcription factors dancing with the right partners. Journal of Leukocyte Biology. 90: 637-8. PMID 21965310 DOI: 10.1189/Jlb.0411187  0.304
2011 Aldana-Masangkay GI, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Hsieh YT, Kim YM, Lomenick B, Okemoto K, Landaw EM, Wang D, Mazitschek R, Bradner JE, Sakamoto KM. Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells. Leukemia & Lymphoma. 52: 1544-55. PMID 21699378 DOI: 10.3109/10428194.2011.570821  0.411
2011 Hernandez-Davies JE, Zape JP, Landaw EM, Tan X, Presnell A, Griffith D, Heinrich MC, Glaser KB, Sakamoto KM. The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway. Molecular Cancer Therapeutics. 10: 949-59. PMID 21471285 DOI: 10.1158/1535-7163.Mct-10-0904  0.37
2011 Danilova N, Sakamoto KM, Lin S. Ribosomal protein L11 mutation in zebrafish leads to haematopoietic and metabolic defects. British Journal of Haematology. 152: 217-28. PMID 21114664 DOI: 10.1111/J.1365-2141.2010.08396.X  0.355
2011 Aldana-Masangkay GI, Sakamoto KM. The role of HDAC6 in cancer. Journal of Biomedicine & Biotechnology. 2011: 875824. PMID 21076528 DOI: 10.1155/2011/875824  0.366
2011 Aldana-Masangkay GI, Mitton B, Ikeda AK, Yamada K, Li B, Fan Q, Landaw E, Xiao X, Sakamoto KM. A Small Molecule Inhibitor Targeting CREB and CBP Inhibits Proliferation of AML Cells In Vitro and In Vivo, Blood. 118: 3607-3607. DOI: 10.1182/Blood.V118.21.3607.3607  0.445
2011 Sandoval S, Cho M, Kraus C, Cho E, Wolff L, Sakamoto KM. Sox4 and CREB Cooperate in Myeloid Transformation, Blood. 118: 3452-3452. DOI: 10.1182/Blood.V118.21.3452.3452  0.386
2011 Danilova N, Sakamoto KM, Lin S. Beneficial Effects of Nucleoside Treatment in Zebrafish Models of Diamond Blackfan Anemia Deficient in Ribosomal Proteins L11 or S19, Blood. 118: 3439-3439. DOI: 10.1182/Blood.V118.21.3439.3439  0.361
2011 Bibikova E, Lin S, Sakamoto KM. MiR34a Contributes to Defective Erythropoiesis in RPS19 Insufficient Hematopoietic Stem Cells Blood. 118: 2404-2404. DOI: 10.1182/Blood.V118.21.2404.2404  0.425
2010 Lin TL, Wang QH, Brown P, Peacock C, Merchant AA, Brennan S, Jones E, McGovern K, Watkins DN, Sakamoto KM, Matsui W. Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926. Plos One. 5: e15262. PMID 21203400 DOI: 10.1371/Journal.Pone.0015262  0.362
2010 Wen AY, Sakamoto KM, Miller LS. The role of the transcription factor CREB in immune function. Journal of Immunology (Baltimore, Md. : 1950). 185: 6413-9. PMID 21084670 DOI: 10.4049/Jimmunol.1001829  0.358
2010 Niemeyer CM, Kang MW, Shin DH, Furlan I, Erlacher M, Bunin NJ, Bunda S, Finklestein JZ, Sakamoto KM, Gorr TA, Mehta P, Schmid I, Kropshofer G, Corbacioglu S, Lang PJ, et al. Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. Nature Genetics. 42: 794-800. PMID 20694012 DOI: 10.1038/Ng.641  0.339
2010 Wu WK, Sakamoto KM, Milani M, Aldana-Masankgay G, Fan D, Wu K, Lee CW, Cho CH, Yu J, Sung JJ. Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 13: 87-92. PMID 20462785 DOI: 10.1016/J.Drup.2010.04.003  0.368
2010 Xiao X, Li BX, Mitton B, Ikeda A, Sakamoto KM. Targeting CREB for cancer therapy: friend or foe. Current Cancer Drug Targets. 10: 384-91. PMID 20370681 DOI: 10.2174/156800910791208535  0.413
2010 Ikeda AK, Judelson DR, Federman N, Glaser KB, Landaw EM, Denny CT, Sakamoto KM. ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways. Molecular Cancer Therapeutics. 9: 653-60. PMID 20197394 DOI: 10.1158/1535-7163.Mct-09-0812  0.389
2010 Sakamoto KM. Protacs for treatment of cancer. Pediatric Research. 67: 505-8. PMID 20075761 DOI: 10.1203/Pdr.0B013E3181D35017  0.347
2010 Manara E, Baron E, Beghin A, Tregnago C, Giarin E, Sakamoto KM, Pigazzi M, Basso G. MiR-34b Promoter Methylation and Regulation of CREB Expression In Myeloid Transformation Blood. 116: 538-538. DOI: 10.1182/Blood.V116.21.538.538  0.304
2010 Tasian SK, Doral MY, Wood BL, Borowitz MJ, Collins-Underwood JR, Harvey RC, Sakamoto KM, Willman CL, Hunger SP, Mullighan CG, Loh ML. Thymic Stromal Lymphopoietin Stimulation of Pediatric Acute Lymphoblastic Leukemias with CRLF2 Alterations Induces JAK/STAT and PI3K Phosphosignaling Blood. 116: 410-410. DOI: 10.1182/Blood.V116.21.410.410  0.39
2010 Mitton B, Ikeda A, Yamada K, Li B, Fan Q, Landaw E, Xiao X, Sakamoto KM. Inhibitor of the CREB Proto-Oncogene Suppresses AML Cell Proliferation and Induces Apoptosis In Vitro and In Vivo Blood. 116: 3270-3270. DOI: 10.1182/Blood.V116.21.3270.3270  0.452
2010 Danilova N, Sakamoto KM, Lin S. Characterization of p53-Dependent Pathways In RPL11 Mutant Zebrafish Blood. 116: 2227-2227. DOI: 10.1182/Blood.V116.21.2227.2227  0.424
2010 Simms-Waldrip T, Cho MY, Dorshkind K, Sakamoto KM. CREB Regulates Early Myelopoiesis and Myeloid Engraftment. Blood. 116: 1452-1452. DOI: 10.1182/Blood.V116.21.1452.1452  0.404
2009 Sandoval S, Pigazzi M, Sakamoto KM. CREB: A Key Regulator of Normal and Neoplastic Hematopoiesis. Advances in Hematology. 2009: 634292. PMID 19960054 DOI: 10.1155/2009/634292  0.436
2009 Sakamoto KM, Frank DA. CREB in the pathophysiology of cancer: implications for targeting transcription factors for cancer therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2583-7. PMID 19351775 DOI: 10.1158/1078-0432.Ccr-08-1137  0.423
2008 Danilova N, Sakamoto KM, Lin S. p53 family in development. Mechanisms of Development. 125: 919-31. PMID 18835440 DOI: 10.1016/J.Mod.2008.09.003  0.309
2008 Pellegrini M, Cheng JC, Voutila J, Judelson D, Taylor J, Nelson SF, Sakamoto KM. Expression profile of CREB knockdown in myeloid leukemia cells. Bmc Cancer. 8: 264. PMID 18801183 DOI: 10.1186/1471-2407-8-264  0.443
2008 Rodriguez-Gonzalez A, Cyrus K, Salcius M, Kim K, Crews CM, Deshaies RJ, Sakamoto KM. Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer. Oncogene. 27: 7201-11. PMID 18794799 DOI: 10.1038/Onc.2008.320  0.59
2008 Rajasekaran SA, Christiansen JJ, Schmid I, Oshima E, Ryazantsev S, Sakamoto K, Weinstein J, Rao NP, Rajasekaran AK. Prostate-specific membrane antigen associates with anaphase-promoting complex and induces chromosomal instability. Molecular Cancer Therapeutics. 7: 2142-51. PMID 18645024 DOI: 10.1158/1535-7163.Mct-08-0005  0.314
2008 Danilova N, Sakamoto KM, Lin S. Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family. Blood. 112: 5228-37. PMID 18515656 DOI: 10.1182/Blood-2008-01-132290  0.358
2008 Simms-Waldrip T, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Fu C, Sakamoto KM. The aggresome pathway as a target for therapy in hematologic malignancies. Molecular Genetics and Metabolism. 94: 283-6. PMID 18472289 DOI: 10.1016/J.Ymgme.2008.03.012  0.356
2008 Rodriguez-Gonzalez A, Lin T, Ikeda AK, Simms-Waldrip T, Fu C, Sakamoto KM. Role of the aggresome pathway in cancer: targeting histone deacetylase 6-dependent protein degradation. Cancer Research. 68: 2557-60. PMID 18413721 DOI: 10.1158/0008-5472.Can-07-5989  0.372
2008 Cheng JC, Kinjo K, Judelson DR, Chang J, Wu WS, Schmid I, Shankar DB, Kasahara N, Stripecke R, Bhatia R, Landaw EM, Sakamoto KM. CREB is a critical regulator of normal hematopoiesis and leukemogenesis. Blood. 111: 1182-92. PMID 17975014 DOI: 10.1182/Blood-2007-04-083600  0.457
2008 Esparza SD, Chang J, Shankar DB, Zhang B, Nelson SF, Sakamoto KM. CREB regulates Meis1 expression in normal and malignant hematopoietic cells. Leukemia. 22: 665-7. PMID 17805329 DOI: 10.1038/Sj.Leu.2404933  0.389
2008 Sakamoto KM. The Role of GM-CSF Signaling and CREB in Myeloid Proliferation and Survival. Blood. 112: sci-33-sci-33. DOI: 10.1182/Blood.V112.11.Sci-33.Sci-33  0.473
2008 Danilova N, Morimoto K, Sakamoto KM, Lin S. Aberrant p53 Signaling Pathways in RPL11 Mutant Zebrafish Blood. 112: 37-37. DOI: 10.1182/Blood.V112.11.37.37  0.38
2008 Hernandez JE, Zape J, Glaser K, Landaw E, Fu C, Sakamoto KM. Multi-Targeted Receptor Tyrosine Kinase Inhibitor, ABT-869, Induces Apoptosis and Suppresses Proliferation of Ba/F3 FLT-3 ITD Mutant Cells in Vitro and in Vivo through Inhibition of FLT3 and AKT. Blood. 112: 1938-1938. DOI: 10.1182/Blood.V112.11.1938.1938  0.378
2008 Rodriguez-Gonzalez A, Simms-Waldrip T, Ikeda AK, Lin T, Lomenick B, Aldana-Masangkay G, Mazitschek R, Bradner J, Fu C, Sakamoto KM. Tubacin, An Inhibitor of HDAC6, Induces Apoptosis of Acute Lymphoblastic Leukemia Cells in Vitro and in Vivo through a Na+/K+ATPase-Dependent Pathway. Blood. 112: 1923-1923. DOI: 10.1182/Blood.V112.11.1923.1923  0.402
2008 Sakamoto K, Rodriguez-Gonzalez A, Cyrus K, Kim K, Crews C, Deshaies R. 39 INVITED Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer European Journal of Cancer Supplements. 6: 16. DOI: 10.1016/S1359-6349(08)71971-2  0.517
2007 Yang Z, Jiang H, Zhao F, Shankar DB, Sakamoto KM, Zhang MQ, Lin S. A highly conserved regulatory element controls hematopoietic expression of GATA-2 in zebrafish. Bmc Developmental Biology. 7: 97. PMID 17708765 DOI: 10.1186/1471-213X-7-97  0.369
2007 Cheng JC, Esparza S, Sandoval S, Shankar D, Fu C, Sakamoto KM. Potential role of CREB as a prognostic marker in acute myeloid leukemia. Future Oncology (London, England). 3: 475-80. PMID 17661722 DOI: 10.2217/14796694.3.4.475  0.417
2007 Shankar DB, Li J, Tapang P, Owen McCall J, Pease LJ, Dai Y, Wei RQ, Albert DH, Bouska JJ, Osterling DJ, Guo J, Marcotte PA, Johnson EF, Soni N, Hartandi K, ... ... Sakamoto KM, et al. ABT-869, a multitargeted receptor tyrosine kinase inhibitor: inhibition of FLT3 phosphorylation and signaling in acute myeloid leukemia. Blood. 109: 3400-8. PMID 17209055 DOI: 10.1182/Blood-2006-06-029579  0.381
2007 Ikeda AK, Judelson D, Li J, Wei RQ, Tapang P, Davidsen SK, Albert DH, Glaser KB, Fu C, Sakamoto KM. Targeting FLT3 Phosphorylation and Signaling in Acute Myeloid Leukemia. Blood. 110: 912-912. DOI: 10.1182/Blood.V110.11.912.912  0.404
2007 Danilova N, Sakamoto K, Lin S. Imbalance of p53 Family Members as a New Target of Therapeutics for Treatment of Diamond Blackfan Anemia. Blood. 110: 423-423. DOI: 10.1182/Blood.V110.11.423.423  0.387
2007 Rodriguez-Gonzalez A, Ch’ng J, Ikeda AK, Lin T, Bahrami B, Mazitschek R, Bradner JE, Fu C, Sakamoto KM. Targeting Histone Deacetylase 6 and the Aggresome Pathway in Acute Lymphoblastic Leukemia Cells. Blood. 110: 1602-1602. DOI: 10.1182/Blood.V110.11.1602.1602  0.443
2007 Hernandez JE, Li J, Wei R, Tapang P, Davidsen SK, Albert DH, Marcotte PA, Glaser KB, Fu C, Sakamoto KM. Multi-Targeted Receptor Tyrosine Kinase Inhibitor, ABT-869, Induces Apoptosis and Inhibition of Proliferation of Ba/F3 FLT-3 ITD Mutant Cells. Blood. 110: 1589-1589. DOI: 10.1182/Blood.V110.11.1589.1589  0.381
2007 Cheng JC, Judelson D, Kinjo K, Chang J, Landaw E, Sakamoto KM. CREB Plays a Critical Role in the Regulation of Normal and Malignant Hematopoiesis. Blood. 110: 1224-1224. DOI: 10.1182/Blood.V110.11.1224.1224  0.465
2006 Morimoto K, Lin S, Sakamoto K. The functions of RPS19 and their relationship to Diamond-Blackfan anemia: a review. Molecular Genetics and Metabolism. 90: 358-62. PMID 17178250 DOI: 10.1016/J.Ymgme.2006.11.004  0.316
2006 Ikeda A, Shankar DB, Watanabe M, Tamanoi F, Moore TB, Sakamoto KM. Molecular targets and the treatment of myeloid leukemia. Molecular Genetics and Metabolism. 88: 216-24. PMID 16678459 DOI: 10.1016/J.Ymgme.2006.03.011  0.343
2006 Parcells BW, Ikeda AK, Simms-Waldrip T, Moore TB, Sakamoto KM. FMS-like tyrosine kinase 3 in normal hematopoiesis and acute myeloid leukemia. Stem Cells (Dayton, Ohio). 24: 1174-84. PMID 16410383 DOI: 10.1634/Stemcells.2005-0519  0.374
2006 Simms-Waldrip T, Hernandez J, Shankar D, Moore TB, Sakamoto KM. 145 TARGETING BCL-2 IN ACUTE MYELOID LEUKEMIA CELLS. Journal of Investigative Medicine. 54: S105.1-S105. DOI: 10.2310/6650.2005.X0004.144  0.381
2006 Parcells BW, Ikeda AK, Moore TB, Glaser KB, Sakamoto KM. 138 THE MULTITARGETED RECEPTOR TYROSINE KINASE INHIBITOR ABT-869 INDUCES APOPTOSIS IN BAF3 CELLS EXPRESSING THE FLT3 INTERNAL TANDEM DUPLICATION MUTATION. Journal of Investigative Medicine. 54: S103.5-S104. DOI: 10.2310/6650.2005.X0004.137  0.398
2006 Esparza SD, Shankar D, Nelson S, Sakamoto K. Identification of Meis1 as a Target of CREB in Myeloid Leukemogenesis. Blood. 108: 1945-1945. DOI: 10.1182/Blood.V108.11.1945.1945  0.448
2006 Cheng JC, Shankar D, Nelson SF, Sakamoto KM. Requirement of CREB in Normal and Malignant Hematopoiesis. Blood. 108: 1168-1168. DOI: 10.1182/Blood.V108.11.1168.1168  0.474
2006 Martinez-F F, Jimenez-O FA, Machuca-R C, Villegas-C H, Sakamoto K. 970. Transcriptional Activat ion of krox-1 Induced by Sexual Hormones in Osteosarcoma Cells Molecular Therapy. 13: S373-S374. DOI: 10.1016/J.Ymthe.2006.08.1062  0.386
2005 Sakamoto KM. Chimeric molecules to target proteins for ubiquitination and degradation. Methods in Enzymology. 399: 833-47. PMID 16338398 DOI: 10.1016/S0076-6879(05)99054-X  0.389
2005 Shankar DB, Cheng JC, Sakamoto KM. Role of cyclic AMP response element binding protein in human leukemias. Cancer. 104: 1819-24. PMID 16196046 DOI: 10.1002/cncr.21401  0.33
2005 Kinjo K, Sandoval S, Sakamoto KM, Shankar DB. The role of CREB as a proto-oncogene in hematopoiesis. Cell Cycle (Georgetown, Tex.). 4: 1134-5. PMID 16096372 DOI: 10.4161/Cc.4.9.1991  0.447
2005 Shankar DB, Cheng JC, Kinjo K, Federman N, Moore TB, Gill A, Rao NP, Landaw EM, Sakamoto KM. The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia. Cancer Cell. 7: 351-62. PMID 15837624 DOI: 10.1016/J.Ccr.2005.02.018  0.434
2005 Mora-Garcia P, Wei J, Sakamoto KM. G-CSF induces stabilization of ETS protein Fli-1 during myeloid cell development. Pediatric Research. 57: 63-6. PMID 15557108 DOI: 10.1203/01.Pdr.0000147729.55592.2C  0.433
2005 Menzel LP, Shankar DB, Shah NP, Hummerickhouse R, Hagey A, Sakamoto KM, Moore TB. 156 ANALYSIS OF A TARGETED RECEPTOR TYROSINE KINASE INHIBITOR IN THE TREATMENT OF ACUTE MYELOGENOUS LEUKEMIA Journal of Investigative Medicine. 53: S105.1-S105. DOI: 10.2310/6650.2005.00005.155  0.43
2005 Kinjo K, Shankar DB, Moore T, Sakamoto KM. 155 THE CYCLIC ADENOSINE MONOPHOSPHATE RESPONSE ELEMENT BINDING PROTEIN REGULATES HEMATOPOIETIC PROGENITOR CELL PROLIFERATION AND MYELOID ENGRAFTMENT Journal of Investigative Medicine. 53: S104.6-S105. DOI: 10.2310/6650.2005.00005.154  0.366
2005 Shankar DB, Chang JC, Parcells B, Sandoval S, Li J, Wei R, Tapang P, Davidsen SK, Albert DH, Glaser KB, Moore TB, Sakamoto KM. The Multi-Targeted Receptor Tyrosine Kinase Inhibitor, ABT-869, Induces Apoptosis of AML Cells Both In Vitro and In Vivo. Blood. 106: 616-616. DOI: 10.1182/Blood.V106.11.616.616  0.426
2005 Shankar DB, Kinjo K, Chang J, Sakamoto KM. CREB Transgenic Mice Develop Myeloproliferative Disease/Myelodysplastic Syndrome after a Prolonged Latency. Blood. 106: 367-367. DOI: 10.1182/Blood.V106.11.367.367  0.413
2004 Cheng JC, Sakamoto KM. The emerging role of RNA interference in the design of novel therapeutics in oncology. Cell Cycle (Georgetown, Tex.). 3: 1398-401. PMID 15492503 DOI: 10.4161/Cc.3.11.1240  0.321
2004 Verma R, Peters NR, D'Onofrio M, Tochtrop GP, Sakamoto KM, Varadan R, Zhang M, Coffino P, Fushman D, Deshaies RJ, King RW. Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain. Science (New York, N.Y.). 306: 117-20. PMID 15459393 DOI: 10.1126/Science.1100946  0.589
2004 Shankar DB, Sakamoto KM. The role of cyclic-AMP binding protein (CREB) in leukemia cell proliferation and acute leukemias. Leukemia & Lymphoma. 45: 265-70. PMID 15101710 DOI: 10.1080/1042819031000151095  0.415
2004 Schneekloth JS, Fonseca FN, Koldobskiy M, Mandal A, Deshaies R, Sakamoto K, Crews CM. Chemical genetic control of protein levels: selective in vivo targeted degradation. Journal of the American Chemical Society. 126: 3748-54. PMID 15038727 DOI: 10.1021/Ja039025Z  0.59
2004 Wang Q, Liu T, Fang Y, Xie S, Huang X, Mahmood R, Ramaswamy G, Sakamoto KM, Darzynkiewicz Z, Xu M, Dai W. BUBR1 deficiency results in abnormal megakaryopoiesis. Blood. 103: 1278-85. PMID 14576056 DOI: 10.1182/Blood-2003-06-2158  0.375
2004 Shankar DB, Landaw EM, Rao N, Moore TB, Sakamoto KM. CREB Is Amplified in AML Blasts and Is Associated with an Increased Risk of Relapse and Decreased Event-Free Survival. Blood. 104: 573-573. DOI: 10.1182/Blood.V104.11.573.573  0.401
2004 Kinjo K, Shankar DB, Cheng J, Esparza S, Federman N, Moore TB, Sakamoto KM. CREB Overexpression In Vivo Results in Increased Proliferation, Blast Transformation, and Earlier Engraftment of Myeloid Progenitor Cells. Blood. 104: 3548-3548. DOI: 10.1182/Blood.V104.11.3548.3548  0.392
2004 Shankar DB, Kinjo K, Cheng J, Esparza S, Federman N, Moore TB, Sakamoto KM. Cyclin A Is a Target Gene of Activated CREB Downstream of GM-CSF Signaling That Regulates Normal and Malignant Myelopoiesis. Blood. 104: 2181-2181. DOI: 10.1182/Blood.V104.11.2181.2181  0.502
2003 Cheng JC, Moore TB, Sakamoto KM. RNA interference and human disease. Molecular Genetics and Metabolism. 80: 121-8. PMID 14567961 DOI: 10.1016/J.Ymgme.2003.08.011  0.342
2003 Sakamoto KM, Kim KB, Verma R, Ransick A, Stein B, Crews CM, Deshaies RJ. Development of Protacs to target cancer-promoting proteins for ubiquitination and degradation. Molecular & Cellular Proteomics : McP. 2: 1350-8. PMID 14525958 DOI: 10.1074/Mcp.T300009-Mcp200  0.597
2003 Lin M, Chang JK, Shankar D, Sakamoto KM. The role of p55CDC in cell cycle control and mammalian cell proliferation, differentiation, and apoptosis. Experimental and Molecular Pathology. 74: 123-8. PMID 12710943 DOI: 10.1016/S0014-4800(02)00021-7  0.444
2003 Mora-Garcia P, Cheng J, Crans-Vargas HN, Countouriotis A, Shankar D, Sakamoto KM. Transcriptional regulators and myelopoiesis: the role of serum response factor and CREB as targets of cytokine signaling. Stem Cells (Dayton, Ohio). 21: 123-30. PMID 12634408 DOI: 10.1634/stemcells.21-2-123  0.336
2002 Mora-Garcia P, Pan R, Sakamoto KM. G-CSF regulation of SRE-binding proteins in myeloid cells. Leukemia. 16: 2332-3. PMID 12399981 DOI: 10.1038/Sj.Leu.2402686  0.376
2002 Sakamoto KM. Ubiquitin-dependent proteolysis: its role in human diseases and the design of therapeutic strategies. Molecular Genetics and Metabolism. 77: 44-56. PMID 12359129 DOI: 10.1016/S1096-7192(02)00146-4  0.359
2002 Crans-Vargas HN, Landaw EM, Bhatia S, Sandusky G, Moore TB, Sakamoto KM. Expression of cyclic adenosine monophosphate response-element binding protein in acute leukemia. Blood. 99: 2617-9. PMID 11895805 DOI: 10.1182/Blood.V99.7.2617  0.397
2001 Schmid I, Sakamoto KM. Analysis of DNA content and green fluorescent protein expression. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 7.16. PMID 18770728 DOI: 10.1002/0471142956.Cy0716S16  0.319
2001 Xu Z, Dziarski R, Wang Q, Swartz K, Sakamoto KM, Gupta D. Bacterial peptidoglycan-induced tnf-alpha transcription is mediated through the transcription factors Egr-1, Elk-1, and NF-kappaB. Journal of Immunology (Baltimore, Md. : 1950). 167: 6975-82. PMID 11739517 DOI: 10.4049/Jimmunol.167.12.6975  0.338
2001 Shou W, Sakamoto KM, Keener J, Morimoto KW, Traverso EE, Azzam R, Hoppe GJ, Feldman RM, DeModena J, Moazed D, Charbonneau H, Nomura M, Deshaies RJ. Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit. Molecular Cell. 8: 45-55. PMID 11511359 DOI: 10.1016/S1097-2765(01)00291-X  0.694
2001 Sakamoto KM, Kim KB, Kumagai A, Mercurio F, Crews CM, Deshaies RJ. Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation. Proceedings of the National Academy of Sciences of the United States of America. 98: 8554-9. PMID 11438690 DOI: 10.1073/Pnas.141230798  0.569
2001 Lin ML, Sakamoto KM. p55Cdc/cdc20 overexpression promotes early g1/s transition in myeloid cells. Stem Cells (Dayton, Ohio). 19: 205-11. PMID 11359945 DOI: 10.1634/Stemcells.19-3-205  0.39
2001 Crans HN, Sakamoto KM. Transcription factors and translocations in lymphoid and myeloid leukemia. Leukemia. 15: 313-31. PMID 11237053 DOI: 10.1038/Sj.Leu.2402033  0.373
2001 Sakamoto K, Deshaies R, Crews C. Protechials: A novel approach to pharmacological inhibition of protein function Nature Genetics. 27: 83-83. DOI: 10.1038/87274  0.556
2000 Wu H, Lan Z, Li W, Wu S, Weinstein J, Sakamoto KM, Dai W. p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase. Oncogene. 19: 4557-62. PMID 11030144 DOI: 10.1038/Sj.Onc.1203803  0.421
2000 Mora-Garcia P, Sakamoto KM. Granulocyte colony-stimulating factor induces Egr-1 up-regulation through interaction of serum response element-binding proteins. The Journal of Biological Chemistry. 275: 22418-26. PMID 10806199 DOI: 10.1074/Jbc.M001731200  0.389
2000 Kwon EM, Raines MA, Blenis J, Sakamoto KM. Granulocyte-macrophage colony-stimulating factor stimulation results in phosphorylation of cAMP response element-binding protein through activation of pp90RSK. Blood. 95: 2552-8. PMID 10753834 DOI: 10.1182/Blood.V95.8.2552.008K30_2552_2558  0.379
1999 Chu YW, Wang R, Schmid I, Sakamoto KM. Analysis with flow cytometry of green fluorescent protein expression in leukemic cells. Cytometry. 36: 333-9. PMID 10404149 DOI: 10.1002/(Sici)1097-0320(19990801)36:4<333::Aid-Cyto8>3.0.Co;2-F  0.358
1999 Aicher WK, Sakamoto KM, Hack A, Eibel H. Analysis of functional elements in the human Egr-1 gene promoter. Rheumatology International. 18: 207-14. PMID 10399797 DOI: 10.1007/S002960050086  0.357
1999 Rolli M, Kotlyarov A, Sakamoto KM, Gaestel M, Neininger A. Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner. The Journal of Biological Chemistry. 274: 19559-64. PMID 10391889 DOI: 10.1074/Jbc.274.28.19559  0.377
1999 Mora-Garcia P, Sakamoto KM. Cell signaling defects and human disease. Molecular Genetics and Metabolism. 66: 143-71. PMID 10066384 DOI: 10.1006/Mgme.1998.2798  0.301
1998 Lin M, Mendoza M, Kane L, Weinstein J, Sakamoto KM. Analysis of cell death in myeloid cells inducibly expressing the cell cycle protein p55Cdc. Experimental Hematology. 26: 1000-6. PMID 9728936  0.32
1998 Weinstein J, Karim J, Geschwind DH, Nelson SF, Krumm J, Sakamoto KM. Genomic organization, 5' flanking enhancer region, and chromosomal assignment of the cell cycle gene, p55Cdc. Molecular Genetics and Metabolism. 64: 52-7. PMID 9682218 DOI: 10.1006/Mgme.1998.2698  0.402
1997 Watanabe S, Kubota H, Sakamoto KM, Arai K. Characterization of cis-acting sequences and trans-acting signals regulating early growth response 1 and c-fos promoters through the granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells. Blood. 89: 1197-206. PMID 9028942 DOI: 10.1182/Blood.V89.4.1197  0.319
1997 Kwon EM, Raines MA, Sakamoto KM. GM-CSF Induces Phosphorylation of CREB Through Activation of pp90rsk in Myeloid Cells. • 664 Pediatric Research. 41: 113-113. DOI: 10.1203/00006450-199704001-00684  0.424
1996 Horie M, Sakamoto KM, Broxmeyer HE. Regulation of egr-1 gene expression by retinoic acid in a human growth factor-dependent cell line International Journal of Hematology. 63: 303-309. PMID 8762813 DOI: 10.1016/0925-5710(96)00451-3  0.323
1996 Mignacca R, Lee H, Kwon E, Sakamoto K. Mechanism of transcriptional activation of the immediate early gene Egr- 1 in response to PIXY321 Blood. 88: 848-854. DOI: 10.1182/Blood.V88.3.848.Bloodjournal883848  0.4
1995 Wong A, Sakamoto KM. Granulocyte-Macrophage Colony-stimulating Factor Induces the Transcriptional Activation of egr-1 through a Protein Kinase A-independent Signaling Pathway Journal of Biological Chemistry. 270: 30271-30273. PMID 8530445 DOI: 10.1074/Jbc.270.51.30271  0.395
1995 Lee HJ, Mignacca RC, Sakamoto KM. Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133. The Journal of Biological Chemistry. 270: 15979-83. PMID 7608156 DOI: 10.1074/Jbc.270.27.15979  0.356
1994 Sakamoto KM, Fraser JK, Lee HJ, Lehman E, Gasson JC. Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter. Molecular and Cellular Biology. 14: 5975-85. PMID 8065330 DOI: 10.1128/Mcb.14.9.5975  0.373
1991 Sakamoto KM, Golde DW, Gasson JC. The biology and clinical applications of granulocyte-macrophage colony-stimulating factor. The Journal of Pediatrics. 118: S17-20. PMID 1999769 DOI: 10.1016/S0022-3476(05)82185-7  0.338
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