David E. Clouthier - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Cell Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kanai SM, Clouthier DE. Endothelin signaling in development. Development (Cambridge, England). 150. PMID 38078652 DOI: 10.1242/dev.201786  0.377
2023 Baxi A, Jourdeuil K, Cox TC, Clouthier DE, Tavares ALP. Transcriptomic analysis reveals the role of SIX1 in mouse cranial neural crest patterning and bone development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 37183792 DOI: 10.1002/dvdy.597  0.345
2022 Prummel KD, Crowell HL, Nieuwenhuize S, Brombacher EC, Daetwyler S, Soneson C, Kresoja-Rakic J, Kocere A, Ronner M, Ernst A, Labbaf Z, Clouthier DE, Firulli AB, Sánchez-Iranzo H, Naganathan SR, et al. Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma. Nature Communications. 13: 1677. PMID 35354817 DOI: 10.1038/s41467-022-29311-7  0.407
2022 Kanai SM, Heffner C, Cox TC, Cunningham ML, Perez FA, Bauer A, Reigan P, Carter C, Murray SA, Clouthier DE. Auriculocondylar Syndrome 2 results from dominant negative action of PLCB4 variants. Disease Models & Mechanisms. PMID 35284927 DOI: 10.1242/dmm.049320  0.31
2021 Abe M, Cox TC, Firulli AB, Kanai SM, Dalhka J, Lim KC, Engel JD, Clouthier DE. GATA3 is essential for separating patterning domains during facial morphogenesis. Development (Cambridge, England). PMID 34383890 DOI: 10.1242/dev.199534  0.412
2020 Eisenhoffer GT, Clouthier D, Cox T, Saint-Jeannet JP, Taneyhill LA, Trainor PA, Moody SA. The Society for Craniofacial Genetics and Developmental Biology 42nd Annual Meeting. American Journal of Medical Genetics. Part A. PMID 32352199 DOI: 10.1002/Ajmg.A.61602  0.374
2020 Vincentz JW, Clouthier DE, Firulli AB. Mis-Expression of a Cranial Neural Crest Cell-Specific Gene Program in Cardiac Neural Crest Cells Modulates HAND Factor Expression, Causing Cardiac Outflow Tract Phenotypes. Journal of Cardiovascular Development and Disease. 7. PMID 32325975 DOI: 10.3390/Jcdd7020013  0.47
2020 Pritchard AB, Kanai SM, Krock B, Schindewolf E, Oliver-Krasinski J, Khalek N, Okashah N, Lambert NA, Tavares ALP, Zackai E, Clouthier DE. Loss-of-function of Endothelin receptor type A results in Oro-Oto-Cardiac syndrome. American Journal of Medical Genetics. Part A. PMID 32133772 DOI: 10.1002/Ajmg.A.61531  0.411
2019 Xu J, Liu H, Lan Y, Adam M, Clouthier DE, Potter S, Jiang R. Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. Elife. 8. PMID 30638444 DOI: 10.7554/Elife.40315  0.46
2018 Sharma PP, MacLean AL, Meinecke L, Clouthier DE, Nie Q, Schilling TF. Transcriptomics reveals complex kinetics of dorsal-ventral patterning gene expression in the mandibular arch. Genesis (New York, N.Y. : 2000). e23275. PMID 30561090 DOI: 10.1002/Dvg.23275  0.456
2018 Sottnik JL, Mallaredy V, Chauca-Diaz A, Ritterson Lew C, Owens C, Dancik GM, Pagliarani S, Lucchiari S, Moggio M, Ripolone M, Comi GP, Frierson HF, Clouthier D, Theodorescu D. Elucidating the role of Agl in bladder carcinogenesis by generation and characterization of genetically engineered mice. Carcinogenesis. PMID 30403777 DOI: 10.1093/Carcin/Bgy139  0.39
2018 Xu J, Liu H, Lan Y, Adam M, Clouthier DE, Potter S, Jiang R. Author response: Hedgehog signaling patterns the oral-aboral axis of the mandibular arch Elife. DOI: 10.7554/Elife.40315.038  0.328
2017 Tavares ALP, Cox TC, Maxson RM, Ford HL, Clouthier DE. Negative regulation of Endothelin signaling by SIX1 is required for proper maxillary development. Development (Cambridge, England). PMID 28455376 DOI: 10.1242/Dev.145144  0.497
2017 Iklé JM, Tavares AL, King M, Ding H, Colombo S, Firulli BA, Fiulli AB, Targoff KL, Yelon D, Clouthier DE. Nkx2.5 regulates Endothelin Converting Enzyme-1 during pharyngeal arch patterning. Genesis (New York, N.Y. : 2000). PMID 28109039 DOI: 10.1002/Dvg.23021  0.718
2016 Ding HL, Hooper JE, Batzel P, Eames BF, Postlethwait JH, Artinger KB, Clouthier DE. MicroRNA Profiling during Craniofacial Development: Potential Roles for Mir23b and Mir133b. Frontiers in Physiology. 7: 281. PMID 27471470 DOI: 10.3389/Fphys.2016.00281  0.439
2016 Vincentz JW, Casasnovas JJ, Barnes RM, Que J, Clouthier DE, Wang J, Firulli AB. Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap. Proceedings of the National Academy of Sciences of the United States of America. PMID 27335460 DOI: 10.1073/Pnas.1603930113  0.471
2015 Van Otterloo E, Feng W, Jones KL, Hynes NE, Clouthier DE, Niswander L, Williams T. MEMO1 drives cranial endochondraL ossification and palatogenesis. Developmental Biology. PMID 26746790 DOI: 10.1016/J.Ydbio.2015.12.024  0.481
2015 Tavares AL, Artinger KB, Clouthier DE. Regulating Craniofacial Development at the 3' End: MicroRNAs and Their Function in Facial Morphogenesis. Current Topics in Developmental Biology. 115: 335-75. PMID 26589932 DOI: 10.1016/Bs.Ctdb.2015.08.001  0.332
2015 Van Laarhoven PM, Neitzel LR, Quintana AM, Geiger EA, Zackai EH, Clouthier DE, Artinger KB, Ming JE, Shaikh TH. Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development. Human Molecular Genetics. 24: 4443-53. PMID 25972376 DOI: 10.1093/Hmg/Ddv180  0.351
2015 Gordon CT, Weaver KN, Zechi-Ceide RM, Madsen EC, Tavares AL, Oufadem M, Kurihara Y, Adameyko I, Picard A, Breton S, Pierrot S, Biosse-Duplan M, Voisin N, Masson C, Bole-Feysot C, ... ... Clouthier DE, et al. Mutations in the endothelin receptor type A cause mandibulofacial dysostosis with alopecia. American Journal of Human Genetics. 96: 519-31. PMID 25772936 DOI: 10.1016/J.Ajhg.2015.01.015  0.388
2015 Tavares AL, Clouthier DE. Cre recombinase-regulated Endothelin1 transgenic mouse lines: novel tools for analysis of embryonic and adult disorders. Developmental Biology. 400: 191-201. PMID 25725491 DOI: 10.1016/J.Ydbio.2015.01.027  0.49
2014 Firulli BA, Fuchs RK, Vincentz JW, Clouthier DE, Firulli AB. Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis. Development (Cambridge, England). 141: 3050-61. PMID 25053435 DOI: 10.1242/Dev.107680  0.472
2013 Clouthier DE, Passos-Bueno MR, Tavares AL, Lyonnet S, Amiel J, Gordon CT. Understanding the basis of auriculocondylar syndrome: Insights from human, mouse and zebrafish genetic studies. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 163: 306-17. PMID 24123988 DOI: 10.1002/Ajmg.C.31376  0.443
2013 Feng W, Choi I, Clouthier DE, Niswander L, Williams T. The Ptch1(DL) mouse: a new model to study lambdoid craniosynostosis and basal cell nevus syndrome-associated skeletal defects. Genesis (New York, N.Y. : 2000). 51: 677-89. PMID 23897749 DOI: 10.1002/Dvg.22416  0.405
2013 Ding HL, Clouthier DE, Artinger KB. Redundant roles of PRDM family members in zebrafish craniofacial development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 67-79. PMID 23109401 DOI: 10.1002/Dvdy.23895  0.47
2012 Tavares AL, Garcia EL, Kuhn K, Woods CM, Williams T, Clouthier DE. Ectodermal-derived Endothelin1 is required for patterning the distal and intermediate domains of the mouse mandibular arch. Developmental Biology. 371: 47-56. PMID 22902530 DOI: 10.1016/J.Ydbio.2012.08.003  0.525
2012 Iklé JM, Artinger KB, Clouthier DE. Identification and characterization of the zebrafish pharyngeal arch-specific enhancer for the basic helix-loop-helix transcription factor Hand2. Developmental Biology. 368: 118-26. PMID 22595513 DOI: 10.1016/J.Ydbio.2012.05.003  0.703
2011 Barron F, Woods C, Kuhn K, Bishop J, Howard MJ, Clouthier DE. Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis. Development (Cambridge, England). 138: 2249-59. PMID 21558373 DOI: 10.1242/Dev.056929  0.555
2011 Ikle J, Artinger K, Clouthier D. Nkx2.5 regulates hand2 expression in the zebrafish pharyngeal arches via a conserved enhancer Developmental Biology. 356: 233. DOI: 10.1016/J.Ydbio.2011.05.394  0.465
2011 Tavares ALP, Garcia E, Kuhn K, Woods C, Williams T, Clouthier D. Ectodermal-specific inactivation of Endothelin-1 causes craniofacial developmental defects in mice Developmental Biology. 356: 232-233. DOI: 10.1016/J.Ydbio.2011.05.393  0.379
2010 Clouthier DE, Garcia E, Schilling TF. Regulation of facial morphogenesis by endothelin signaling: insights from mice and fish. American Journal of Medical Genetics. Part A. 152: 2962-73. PMID 20684004 DOI: 10.1002/Ajmg.A.33568  0.506
2010 Ikle J, Clouthier DE. Transcriptional regulation of hand2 in zebrafish neural crest cells and cardiomyocytes Developmental Biology. 344: 460. DOI: 10.1016/J.Ydbio.2010.05.192  0.438
2010 Clouthier D, Howard M, Hyndman F. Hand2 regulates both ectodermal and neural crest cell identity during lower jaw development Developmental Biology. 344: 460. DOI: 10.1016/J.Ydbio.2010.05.191  0.448
2010 Kwok L, Clouthier DE, Artinger KB. prdm genes in zebrafish craniofacial development Developmental Biology. 344: 459-460. DOI: 10.1016/J.Ydbio.2010.05.190  0.342
2009 Ruest LB, Clouthier DE. Elucidating timing and function of endothelin-A receptor signaling during craniofacial development using neural crest cell-specific gene deletion and receptor antagonism. Developmental Biology. 328: 94-108. PMID 19185569 DOI: 10.1016/J.Ydbio.2009.01.005  0.509
2008 Clouthier DE, Gray J, Artinger KB. Micromanaging Palate Development. Perspectives On Speech Science and Orofacial Disorders. 18: 62-72. PMID 20016765 DOI: 10.1044/Ssod18.2.62  0.309
2008 Hendershot TJ, Liu H, Clouthier DE, Shepherd IT, Coppola E, Studer M, Firulli AB, Pittman DL, Howard MJ. Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons. Developmental Biology. 319: 179-91. PMID 18501887 DOI: 10.1016/J.Ydbio.2008.03.036  0.462
2008 Clouthier DE. MicroRNAs in facial development. Nature Genetics. 40: 268-9. PMID 18305475 DOI: 10.1038/Ng0308-268  0.374
2007 Abe M, Ruest LB, Clouthier DE. Fate of cranial neural crest cells during craniofacial development in endothelin-A receptor-deficient mice. The International Journal of Developmental Biology. 51: 97-105. PMID 17294360 DOI: 10.1387/Ijdb.062237Ma  0.527
2007 Hendershot TJ, Liu H, Sarkar AA, Giovannucci DR, Clouthier DE, Abe M, Howard MJ. Expression of Hand2 is sufficient for neurogenesis and cell type-specific gene expression in the enteric nervous system. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 93-105. PMID 17075884 DOI: 10.1002/Dvdy.20989  0.417
2005 Kanzaki-Kato N, Tamakoshi T, Fu Y, Chandra A, Itakura T, Uezato T, Tanaka T, Clouthier DE, Sugiyama T, Yanagisawa M, Miura N. Roles of forkhead transcription factor Foxc2 (MFH-1) and endothelin receptor A in cardiovascular morphogenesis. Cardiovascular Research. 65: 711-8. PMID 15664398 DOI: 10.1016/J.Cardiores.2004.10.017  0.398
2005 Ruest LB, Kedzierski R, Yanagisawa M, Clouthier DE. Deletion of the endothelin-A receptor gene within the developing mandible. Cell and Tissue Research. 319: 447-53. PMID 15647918 DOI: 10.1007/S00441-004-0988-1  0.528
2004 Ruest LB, Xiang X, Lim KC, Levi G, Clouthier DE. Endothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identity. Development (Cambridge, England). 131: 4413-23. PMID 15306564 DOI: 10.1242/Dev.01291  0.575
2004 Clouthier DE, Schilling TF. Understanding endothelin-1 function during craniofacial development in the mouse and zebrafish. Birth Defects Research. Part C, Embryo Today : Reviews. 72: 190-9. PMID 15269892 DOI: 10.1002/Bdrc.20007  0.5
2003 Ruest LB, Hammer RE, Yanagisawa M, Clouthier DE. Dlx5/6-enhancer directed expression of Cre recombinase in the pharyngeal arches and brain. Genesis (New York, N.Y. : 2000). 37: 188-94. PMID 14666512 DOI: 10.1002/Gene.10247  0.485
2003 Clouthier DE, Williams SC, Hammer RE, Richardson JA, Yanagisawa M. Cell-autonomous and nonautonomous actions of endothelin-A receptor signaling in craniofacial and cardiovascular development. Developmental Biology. 261: 506-19. PMID 14499656 DOI: 10.1016/S0012-1606(03)00128-3  0.415
2003 Ruest LB, Dager M, Yanagisawa H, Charité J, Hammer RE, Olson EN, Yanagisawa M, Clouthier DE. dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. Developmental Biology. 257: 263-77. PMID 12729557 DOI: 10.1016/S0012-1606(03)00068-X  0.53
2003 Comerford SA, Clouthier DE, Hinnant EA, Hammer RE. Induction of hepatocyte proliferation and death by modulation of T-Antigen expression. Oncogene. 22: 2515-30. PMID 12717428 DOI: 10.1038/Sj.Onc.1206259  0.328
2003 Yanagisawa H, Clouthier DE, Richardson JA, Charité J, Olson EN. Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development. Development (Cambridge, England). 130: 1069-78. PMID 12571099 DOI: 10.1242/Dev.00337  0.542
2001 Charité J, McFadden DG, Merlo G, Levi G, Clouthier DE, Yanagisawa M, Richardson JA, Olson EN. Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer. Genes & Development. 15: 3039-49. PMID 11711438 DOI: 10.1101/Gad.931701  0.49
2000 Yanagisawa H, Hammer RE, Richardson JA, Emoto N, Williams SC, Takeda Si, Clouthier DE, Yanagisawa M. Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development. The Journal of Clinical Investigation. 105: 1373-82. PMID 10811845 DOI: 10.1172/Jci7447  0.394
2000 Clouthier DE, Williams SC, Yanagisawa H, Wieduwilt M, Richardson JA, Yanagisawa M. Signaling Pathways Crucial for Craniofacial Development Revealed by Endothelin-A Receptor-Deficient Mice Developmental Biology. 217: 10-24. PMID 10625532 DOI: 10.1006/Dbio.1999.9527  0.563
1999 Devine JH, Eubank DW, Clouthier DE, Tontonoz P, Spiegelman BM, Hammer RE, Beale EG. Adipose expression of the phosphoenolpyruvate carboxykinase promoter requires peroxisome proliferator-activated receptor gamma and 9-cis-retinoic acid receptor binding to an adipocyte-specific enhancer in vivo. The Journal of Biological Chemistry. 274: 13604-12. PMID 10224131 DOI: 10.1074/Jbc.274.19.13604  0.391
1998 Yanagisawa H, Hammer RE, Richardson JA, Williams SC, Clouthier DE, Yanagisawa M. Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice. The Journal of Clinical Investigation. 102: 22-33. PMID 9649553 DOI: 10.1172/Jci2698  0.473
1997 Clouthier DE, Comerford SA, Hammer RE. Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice. The Journal of Clinical Investigation. 100: 2697-713. PMID 9389733 DOI: 10.1172/Jci119815  0.345
1993 Beale EG, Clouthier DE, Hammer RE. Cell-specific expression of cytosolic phosphoenolpyruvate carboxykinase in transgenic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 3330-7. PMID 1281456 DOI: 10.1096/Fasebj.6.15.1281456  0.401
1992 Short MK, Clouthier DE, Schaefer IM, Hammer RE, Magnuson MA, Beale EG. Tissue-specific, developmental, hormonal, and dietary regulation of rat phosphoenolpyruvate carboxykinase-human growth hormone fusion genes in transgenic mice. Molecular and Cellular Biology. 12: 1007-20. PMID 1545785 DOI: 10.1128/Mcb.12.3.1007  0.418
1992 Herz J, Clouthier DE, Hammer RE. LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation. Cell. 71: 411-21. PMID 1423604 DOI: 10.1016/0092-8674(92)90511-A  0.35
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