| Year |
Citation |
Score |
| 2022 |
Davidson RK, Weaver SA, Casey N, Kanojia S, Hogarth E, Schneider Aguirre R, Sims EK, Evans-Molina C, Spaeth JM. The Chd4 subunit of the NuRD complex regulates Pdx1-controlled genes involved in β-cell function. Journal of Molecular Endocrinology. PMID 35521759 DOI: 10.1530/JME-22-0011 |
0.348 |
|
| 2021 |
Simonett SP, Shin S, Herring JA, Bacher R, Smith LA, Dong C, Rabaglia ME, Stapleton DS, Schueler KL, Choi J, Bernstein MN, Turkewitz DR, Perez-Cervantes C, Spaeth J, Stein R, et al. Identification of direct transcriptional targets of NFATC2 that promote β-cell proliferation. The Journal of Clinical Investigation. PMID 34491912 DOI: 10.1172/JCI144833 |
0.37 |
|
| 2020 |
Davidson RK, Kanojia S, Spaeth JM. The Contribution of Transcriptional Coregulators in the Maintenance of β-cell Function and Identity. Endocrinology. PMID 33211800 DOI: 10.1210/endocr/bqaa213 |
0.333 |
|
| 2020 |
Davidson RK, Casey N, Spaeth J. 2049-P: The Chd4 Helicase of the Nucleosome Remodeling and Deacetylase Complex Modulates Pdx1 Target Gene Expression In Vitro Diabetes. 69. DOI: 10.2337/Db20-2049-P |
0.335 |
|
| 2019 |
Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R. The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function. Diabetes. PMID 31201281 DOI: 10.2337/Db19-0349 |
0.443 |
|
| 2019 |
Wilson CS, Spaeth JM, Karp J, Stocks BT, Hoopes EM, Stein RW, Moore DJ. B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib. Jci Insight. 5. PMID 30964447 DOI: 10.1172/Jci.Insight.125317 |
0.35 |
|
| 2019 |
Russell MA, Redick SD, Blodgett DM, Richardson SJ, Leete P, Krogvold L, Dahl-Jørgensen K, Bottino R, Brissova M, Spaeth JM, Babon JAB, Haliyur R, Powers AC, Yang C, Kent SC, et al. HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of islet β-Cells from Donors with Type 1 Diabetes. Diabetes. PMID 30833470 DOI: 10.2337/Db18-0686 |
0.348 |
|
| 2018 |
Park MJ, Shen H, Spaeth JM, Tolvanen JH, Failor C, Knudtson JF, McLaughlin J, Halder SK, Yang Q, Bulun SE, Al-Hendy A, Schenken RS, Aaltonen LA, Boyer TG. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of Cyclin C-CDK8/19. The Journal of Biological Chemistry. PMID 29440396 DOI: 10.1074/Jbc.Ra118.001725 |
0.632 |
|
| 2017 |
Spaeth JM, Gupte M, Perelis M, Yang YP, Cyphert H, Guo S, Liu JH, Guo M, Bass J, Magnuson MA, Wright C, Stein R. Defining a Novel Role for the PDX1 Transcription Factor in Islet β Cell Maturation and Proliferation During Weaning. Diabetes. PMID 28705881 DOI: 10.2337/Db16-1516 |
0.436 |
|
| 2017 |
Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, et al. Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation. Cell Metabolism. 25: 1362-1373.e5. PMID 28591638 DOI: 10.1016/J.Cmet.2017.05.011 |
0.336 |
|
| 2016 |
Spaeth JM, Walker EM, Stein R. Impact of Pdx1-associated chromatin modifiers on islet β-cells. Diabetes, Obesity & Metabolism. 18: 123-7. PMID 27615141 DOI: 10.1111/Dom.12730 |
0.414 |
|
| 2016 |
Clark A, Oldenbroek M, Wang Y, Spaeth J, Gao F, Jin VX, Boyer T. Abstract 4607: Mediator kinase module as a transducer of oncogenic Wnt/beta-catenin signaling Cancer Research. 76: 4607-4607. DOI: 10.1158/1538-7445.Am2016-4607 |
0.611 |
|
| 2015 |
Conrad E, Dai C, Spaeth J, Guo M, Cyphert HA, Scoville D, Carroll J, Yu WM, Goodrich LV, Harlan DM, Grove KL, Roberts CT, Powers AC, Gu G, Stein R. The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00285.2015. PMID 26554594 DOI: 10.1152/Ajpendo.00285.2015 |
0.37 |
|
| 2015 |
Spaeth JM, Hunter CS, Bonatakis L, Guo M, French CA, Slack I, Hara M, Fisher SE, Ferrer J, Morrisey EE, Stanger BZ, Stein R. The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice. Diabetologia. PMID 26021489 DOI: 10.1007/S00125-015-3635-3 |
0.342 |
|
| 2014 |
Turunen M, Spaeth JM, Keskitalo S, Park MJ, Kivioja T, Clark AD, Mäkinen N, Gao F, Palin K, Nurkkala H, Vähärautio A, Aavikko M, Kämpjärvi K, Vahteristo P, Kim CA, et al. Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity. Cell Reports. 7: 654-60. PMID 24746821 DOI: 10.1016/J.Celrep.2014.03.047 |
0.633 |
|
| 2012 |
Zhou H, Spaeth JM, Kim NH, Xu X, Friez MJ, Schwartz CE, Boyer TG. MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 19763-8. PMID 23091001 DOI: 10.1073/Pnas.1121120109 |
0.628 |
|
| 2011 |
Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, et al. Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proceedings of the National Academy of Sciences of the United States of America. 108: 19678-82. PMID 22106289 DOI: 10.1073/Pnas.1117835108 |
0.568 |
|
| 2011 |
Spaeth JM, Kim NH, Boyer TG. Mediator and human disease. Seminars in Cell & Developmental Biology. 22: 776-87. PMID 21840410 DOI: 10.1016/J.Semcdb.2011.07.024 |
0.589 |
|
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